Works about DUAL specificity phosphatase 1

Results: 138

Activation of the ERK1/2 Mitogen-Activated Protein Kinase Cascade by Dentin Matrix Protein 1 Promotes Osteoblast Differentiation.

Published in:

Cells Tissues Organs, 2011, v. 194, n. 2-4, p. 255, doi. 10.1159/000324258

By:

Eapen, Asha;
Ramachandran, Amsaveni;
Pratap, Jitesh;
George, Anne

Publication type:

Article

COMPUTATIONAL IDENTIFICATION OF NOVEL TARGETS FOR DRUG CANDIDATE COMPOUNDS.

Published in:

Journal of Research in Pharmacy, 2023, v. 27, p. 9, doi. 10.29228/jrp.455

By:

SUCULARLI, Ceren;
TOZKOPARAN, Birsen;
AYTAC, Sevim Peri

Publication type:

Article

Nr1d1 inhibition mitigates intermittent hypoxia-induced pulmonary hypertension via Dusp1-mediated Erk1/2 deactivation and mitochondrial fission attenuation.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-02219-5

By:

Pan, Zhou;
Yao, Yan;
Liu, Xu;
Wang, Yixuan;
Zhang, Xinyue;
Zha, Shiqian;
Hu, Ke

Publication type:

Article

Personalised medical management of patients with melanoma (part 2).

Published in:

Nowotwory, 2021, v. 71, n. 4, p. 251, doi. 10.5603/NJO.2021.0045

By:

Gil, Justyna;
Łaczmańska, Izabela;
Sąsiadek, Maria M.;
Ziętek, Marcin

Publication type:

Article

Nutritional plane of twin-bearing ewes alters fetal mammary gland biochemical composition and mTOR/MAPK pathway signaling.

Published in:

Journal of Animal Science, 2015, v. 93, n. 2, p. 699, doi. 10.2527/jas.2014-8394

By:

Sciascia, Q.;
Sales, F.;
van der Linden, D.;
Wards, N.;
Oliver, M.;
Blair, H;
McCoard, S.

Publication type:

Article

Interferon β protects against lethal endotoxic and septic shock through SIRT1 upregulation.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep04220

By:

Chae-Hwa Yoo;
Ji-Hyun Yeom;
Jin-Ju Heo;
Eun-Kyung Song;
Sang-Il Lee;
Myung-Kwan Han

Publication type:

Article

The reduced SCFA-producing gut microbes are involved in the inflammatory activation in Kawasaki disease.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1124118

By:

Fangyan Wang;
Fanyu Qian;
Qihao Zhang;
Jian Zhao;
Jianke Cen;
Jiamin Zhang;
Jinhui Zhou;
Ming Luo;
Chang Jia;
Xing Rong;
Maoping Chu

Publication type:

Article

Inhibitors of heat shock protein 90 augment endothelin‑1‑induced heat shock protein 27 through the SAPK/JNK signaling pathway in osteoblasts.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 6, p. 8542, doi. 10.3892/mmr.2018.8878

By:

Fujita, Kazuhiko;
Otsuka, Takanobu;
Kawabata, Tetsu;
Sakai, Go;
Matsushima-Nishiwaki, Rie;
Kozawa, Osamu;
Tokuda, Haruhiko

Publication type:

Article

Angiotensin‑(1‑7) prevents lipopolysaccharide‑induced hepatocellular inflammatory response by inhibiting the p38MAPK/AP‑1 signaling pathway.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 4, p. 5492, doi. 10.3892/mmr.2018.8527

By:

Xiao, Hongli;
Liu, Xiaoya;
Wang, Yan;
Wang, Guoxing;
Yin, Chenghong

Publication type:

Article

Myricetin against ischemic cerebral injury in rat middle cerebral artery occlusion model.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 2, p. 3274, doi. 10.3892/mmr.2017.8212

By:

Sun, Long;
Xu, Peng;
Fu, Tinggang;
Huang, Xin;
Song, Jie;
Chen, Meng;
Tian, Xinghan;
Yin, Hongli;
Han, Jichun

Publication type:

Article

Effects of miR-590 on oxLDL-induced endothelial cell apoptosis: Roles of p53 and NF-κB.

Published in:

Molecular Medicine Reports, 2016, v. 13, n. 1, p. 867, doi. 10.3892/mmr.2015.4606

By:

MEI-HUA BAO;
JIAN-MING LI;
QI-LIANG ZHOU;
GUANG-YI LI;
JIE ZENG;
JUAN ZHAO;
YI-WEN ZHANG

Publication type:

Article

Orally administered betaine reduces photodamage caused by UVB irradiation through the regulation of matrix metalloproteinase-9 activity in hairless mice.

Published in:

Molecular Medicine Reports, 2016, v. 13, n. 1, p. 823, doi. 10.3892/mmr.2015.4613

By:

A-RANG IM;
HEE JEONG LEE;
UI JOUNG YOUN;
JIN WON HYUN;
SUNGWOOK CHAE

Publication type:

Article

B-Raf and the inhibitors: from bench to bedside.

Published in:

Journal of Hematology & Oncology, 2013, v. 6, n. 1, p. 1, doi. 10.1186/1756-8722-6-30

By:

Tiangui Huang;
Karsy, Michael;
Jian Zhuge;
Minghao Zhong;
Delong Liu

Publication type:

Article

Cyclin-dependent kinases as therapeutic targets in melanoma.

Published in:

Pigment Cell & Melanoma Research, 2014, v. 27, n. 3, p. 351, doi. 10.1111/pcmr.12211

By:

Miller, David M.;
Flaherty, Keith T.

Publication type:

Article

Pharmacological Inhibition of ERK Signaling Rescues Pathophysiology and Behavioral Phenotype Associated with 16p11.2 Chromosomal Deletion in Mice.

Published in:

Journal of Neuroscience, 2018, v. 38, n. 30, p. 6640, doi. 10.1523/JNEUROSCI.0515-17.2018

By:

Pucilowska, Joanna;
Vithayathil, Joseph;
Pagani, Marco;
Kelly, Caitlin;
Karlo, J. Colleen;
Robol, Camilla;
Morelia, Ilaria;
Gozzi, Alessandro;
Brambilla, Riccardo;
Landreth, Gary E.

Publication type:

Article

Inhibition of glioblastoma dispersal by the MEK inhibitor PD0325901.

Published in:

2017

By:

Shannon, Stephen;
Dongxuan Jia;
Entersz, Ildiko;
Beelen, Paul;
Miao Yu;
Carcione, Christian;
Carcione, Jonathan;
Mahtabfar, Aria;
Vaca, Connan;
Weaver, Michael;
Shreiber, David;
Zahn, Jeffrey D.;
Liping Liu;
Hao Lin;
Foty, Ramsey A.;
Jia, Dongxuan;
Yu, Miao;
Liu, Liping;
Lin, Hao

Publication type:

journal article

Calpain-2 promotes MKP-1 expression protecting cardiomyocytes in both in vitro and in vivo mouse models of doxorubicin-induced cardiotoxicity.

Published in:

Archives of Toxicology, 2019, v. 93, n. 4, p. 1051, doi. 10.1007/s00204-019-02405-w

By:

Zhang, Yi;
Zheng, Dong;
Ni, Rui;
Peng, Tianqing;
Su, Zhaoliang;
Fan, Guo-Chang;
Robbins, Jeffrey;
Song, Long-Sheng;
Li, Jianmin

Publication type:

Article

Comparative Action of Cardiotonic Steroids on Intracellular Processes in Rat Cortical Neurons.

Published in:

Biochemistry (00062979), 2018, v. 83, n. 2, p. 140, doi. 10.1134/S0006297918020062

By:

Lopachev, A. V.;
Lopacheva, O. M.;
Nikiforova, K. A.;
Filimonov, I. S.;
Fedorova, T. N.;
Akkuratov, E. E.

Publication type:

Article

M1 macrophage‐derived exosomes aggravate bone loss in postmenopausal osteoporosis via a microRNA‐98/DUSP1/JNK axis.

Published in:

Cell Biology International, 2021, v. 45, n. 12, p. 2452, doi. 10.1002/cbin.11690

By:

Yu, Long;
Hu, Ming;
Cui, Xu;
Bao, Da;
Luo, Zhanpeng;
Li, Dawei;
Li, Litao;
Liu, Ning;
Wu, Yunfeng;
Luo, Xiaobo;
Ma, Yuanzheng

Publication type:

Article

VEGFR2 mediated RAS/MAPK signaling pathway to explore the mechanism of Bushen Antai Granule in the treatment of recurrent abortion.

Published in:

Journal of Hainan Medical University, 2021, v. 27, n. 9, p. 30

By:

Wei Chang;
Wei-Li Li;
Sha-Sha Lu

Publication type:

Article

Renal tubular gene biomarkers identification based on immune infiltrates in focal segmental glomerulosclerosis.

Published in:

Renal Failure, 2022, v. 44, n. 1, p. 966, doi. 10.1080/0886022X.2022.2081579

By:

Bai, JunYuan;
Pu, XiaoWei;
Zhang, YunXia;
Dai, Enlai

Publication type:

Article

mRNA Metabolism in Health and Disease.

Published in:

Biomedicines, 2022, v. 10, n. 9, p. 2262, doi. 10.3390/biomedicines10092262

By:

Romão, Luísa

Publication type:

Article

UPF1 Inhibits Hepatocellular Carcinoma Growth through DUSP1/p53 Signal Pathway.

Published in:

Biomedicines, 2022, v. 10, n. 4, p. 793, doi. 10.3390/biomedicines10040793

By:

Lee, Suman;
Hwang, Yukyung;
Kim, Tae Hun;
Jeong, Jaemin;
Choi, Dongho;
Hwang, Jungwook

Publication type:

Article

Ulinastatin attenuates diabetes-induced cardiac dysfunction by the inhibition of inflammation and apoptosis.

Published in:

Experimental & Therapeutic Medicine, 2017, v. 14, n. 3, p. 2497, doi. 10.3892/etm.2017.4824

By:

WEN-KE WANG;
QING-HUA LU;
XIN WANG;
BEN WANG;
JUAN WANG;
HUI-PING GONG;
LIN WANG;
HAO LI;
YI-MENG DU

Publication type:

Article

Astrocyte ERK phosphorylation precedes K.

Published in:

Neuropathology, 2011, v. 31, n. 3, p. 250, doi. 10.1111/j.1440-1789.2010.01172.x

By:

Liping Cai;
Ting Du;
Dan Song;
Baoman Li;
Hertz, Leif;
Liang Peng

Publication type:

Article

Trophoblast cell-derived extracellular vesicles regulate the polarization of decidual macrophages by carrying miR-141-3p in the pathogenesis of preeclampsia.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-76563-y

By:

Wu, Dongcai;
Zhou, Bo;
Hong, Lan;
Cen, Hui;
Wang, Ling;
Ma, Yanlin;
Gong, Humin

Publication type:

Article

IPF-Fibroblast Erk1/2 Activity Is Independent from microRNA Cluster 17-92 but Can Be Inhibited by Treprostinil through DUSP1.

Published in:

Cells (2073-4409), 2021, v. 10, n. 11, p. 2836, doi. 10.3390/cells10112836

By:

Blumer, Sabrina;
Fang, Lei;
Chen, Wei-Chih;
Khan, Petra;
Hostettler, Katrin;
Tamm, Michael;
Roth, Michael;
Lambers, Christopher

Publication type:

Article

Arabidopsis MAP kinase phosphatase 1 and its target MAP kinases 3 and 6 antagonistically determine UV-B stress tolerance, independent of the UVR8 photoreceptor pathway.

Published in:

Plant Journal, 2011, v. 68, n. 4, p. 727, doi. 10.1111/j.1365-313X.2011.04725.x

By:

Besteiro, Marina A. González;
Bartels, Sebastian;
Albert, Andreas;
Ulm, Roman

Publication type:

Article

A structural exposé of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-29673-y

By:

Wang, Huanchen;
Perera, Lalith;
Jork, Nikolaus;
Zong, Guangning;
Riley, Andrew M.;
Potter, Barry V. L.;
Jessen, Henning J.;
Shears, Stephen B.

Publication type:

Article

Ten new cases further delineate the syndromic intellectual disability phenotype caused by mutations in DYRK1A.

Published in:

European Journal of Human Genetics, 2015, v. 23, n. 11, p. 1482, doi. 10.1038/ejhg.2015.29

By:

Bronicki, Lucas M;
Redin, Claire;
Drunat, Severine;
Piton, Amélie;
Lyons, Michael;
Passemard, Sandrine;
Baumann, Clarisse;
Faivre, Laurence;
Thevenon, Julien;
Rivière, Jean-Baptiste;
Isidor, Bertrand;
Gan, Grace;
Francannet, Christine;
Willems, Marjolaine;
Gunel, Murat;
Jones, Julie R;
Gleeson, Joseph G;
Mandel, Jean-Louis;
Stevenson, Roger E;
Friez, Michael J

Publication type:

Article

Highlights on the osteoclast.

Published in:

IBMS BoneKEy, 2012, v. 9, n. 2, p. 22, doi. 10.1038/ibmsbonekey.2012.13

By:

Faccio, Roberta;
Novack, Deborah V

Publication type:

Article

Single-nucleus RNA sequencing identifies cell-type–specific effects of sodium-glucose co-transporter 2 inhibitors in human myocardial slices.

Published in:

European Heart Journal, 2024, v. 45, n. 35, p. 3292, doi. 10.1093/eurheartj/ehae472

By:

Schmidt, Kevin;
Fuchs, Maximilian;
Weber, Natalie;
Werlein, Christopher;
Schmitto, Jan D;
Ius, Fabio;
Ruhparwar, Arjang;
Bär, Christian;
Fiedler, Jan;
Thum, Thomas

Publication type:

Article

Differential regulation of anti-inflammatory genes by p38 MAP kinase and MAP kinase kinase 6.

Published in:

Journal of Inflammation, 2014, v. 11, n. 1, p. 1, doi. 10.1186/1476-9255-11-14

By:

Hammaker, Deepa;
Boyle, David L.;
Topolewski, Katharyn;
Firestein, Gary S.

Publication type:

Article

Glucocorticoid receptor dimerization induces MKP1 to protect against TNF-induced inflammation.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 6, p. 2130, doi. 10.1172/JCI60006

By:

Vandevyver, Sofie;
Dejager, Lien;
Bogaert, Tom Van;
Kleyman, Anna;
Liu, Yusen;
Tuckermann, Jan;
Libert, Claude

Publication type:

Article

Regulation of tristetraprolin expression by mitogen-activated protein kinase phosphatase-1.

Published in:

APMIS, 2012, v. 120, n. 12, p. 988, doi. 10.1111/j.1600-0463.2012.02927.x

By:

Huotari, Noora;
Hömmö, Tuija;
Taimi, Ville;
Nieminen, Riina;
Moilanen, Eeva;
Korhonen, Riku

Publication type:

Article

Retinoic acid ameliorates rheumatoid arthritis by attenuating inflammation and modulating macrophage polarization through MKP-1/MAPK signaling pathway.

Published in:

Korean Journal of Physiology & Pharmacology, 2025, v. 29, n. 1, p. 45, doi. 10.4196/kjpp.24.079

By:

Mengyuan Xin;
Hangyu Jin;
Xiangyu Guo;
Liang Zhao;
Xiangdan Li;
Dongyuan Xu;
Long Zheng;
Lan Liu

Publication type:

Article

Impact of insulin-like growth factor 1 and insulin-like growth factor binding proteins on outcomes in acute myeloid leukemia.

Published in:

Leukemia & Lymphoma, 2015, v. 56, n. 11, p. 3135, doi. 10.3109/10428194.2015.1022767

By:

Karmali, Reem;
Larson, Melissa L.;
Shammo, Jamile M.;
Basu, Sanjib;
Christopherson, Kent;
Borgia, Jeffrey A.;
Venugopal, Parameswaran

Publication type:

Article

miRNA limits MAP kinase-mediated immunity: optimization of plant fitness.

Published in:

Journal of Experimental Botany, 2017, v. 68, n. 21/22, p. 5685, doi. 10.1093/jxb/erx385

By:

Shengjun Li;
Bin Yu

Publication type:

Article

M2 macrophage‐derived exosomal miR‐25‐3p improves high glucose‐induced podocytes injury through activation autophagy via inhibiting DUSP1 expression.

Published in:

IUBMB Life, 2020, v. 72, n. 12, p. 2651, doi. 10.1002/iub.2393

By:

Huang, Haihua;
Liu, Huiyun;
Tang, Jiazhen;
Xu, Wenqiong;
Gan, Huaxia;
Fan, Qiwei;
Zhang, Wei

Publication type:

Article

Effect of miR-101 on the Proliferation and Apoptosis of Goat Hair Follicle Stem Cells.

Published in:

Genes, 2022, v. 13, n. 6, p. 1035, doi. 10.3390/genes13061035

By:

Qu, Jingwen;
Wu, Xi;
Wang, Qiang;
Wang, Jian;
Sun, Xiaomei;
Ji, Dejun;
Li, Yongjun

Publication type:

Article

Cardiac resynchronization therapy reduces expression of inflammation-promoting genes related to interleukin-1β in heart failure.

Published in:

Cardiovascular Research, 2020, v. 116, n. 7, p. 1311, doi. 10.1093/cvr/cvz232

By:

Bilchick, Kenneth;
Kothari, Hema;
Narayan, Aditya;
Garmey, James;
Omar, Abdullah;
Capaldo, Brian;
McNamara, Coleen

Publication type:

Article

Coexpression of human somatostatin receptor-2 (SSTR2) and SSTR3 modulates antiproliferative signaling and apoptosis.

Published in:: Journal of Molecular Signaling, 2012, v. 7, n. 1, p. 5, doi. 10.1186/1750-2187-7-5
Publication type:: Article

Dynamics of Dual Specificity Phosphatases and Their Interplay with Protein Kinases in Immune Signaling.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 9, p. 2086, doi. 10.3390/ijms20092086

By:

Subbannayya, Yashwanth;
Pinto, Sneha M.;
Bösl, Korbinian;
Prasad, T. S. Keshava;
Kandasamy, Richard K.

Publication type:

Article

Differential Responses of OsMPKs in IR56 Rice to Two BPH Populations of Different Virulence Levels.

Published in:

International Journal of Molecular Sciences, 2018, v. 19, n. 12, p. 4030, doi. 10.3390/ijms19124030

By:

Nanda, Satyabrata;
Wan, Pin-Jun;
Yuan, San-Yue;
Lai, Feng-Xiang;
Wang, Wei-Xia;
Fu, Qiang

Publication type:

Article

Epigallocatechin-3-Gallate Suppresses Human Herpesvirus 8 Replication and Induces ROS Leading to Apoptosis and Autophagy in Primary Effusion Lymphoma Cells.

Published in:

International Journal of Molecular Sciences, 2018, v. 19, n. 1, p. 16, doi. 10.3390/ijms19010016

By:

Tsai, Ching-Yi;
Chen, Chang-Yu;
Chiou, Yee-Hsuan;
Shyu, Huey-Wen;
Lin, Kuan-Hua;
Chou, Miao-Chen;
Huang, Mei-Han;
Wang, Yi-Fen

Publication type:

Article

Moracin C, A Phenolic Compound Isolated from Artocarpus heterophyllus, Suppresses Lipopolysaccharide-Activated Inflammatory Responses in Murine Raw264.7 Macrophages.

Published in:

International Journal of Molecular Sciences, 2016, v. 17, n. 8, p. 1199, doi. 10.3390/ijms17081199

By:

Xue Yao;
Dang Wu;
Ningning Dong;
Ping Ouyang;
Jiaqian Pu;
Qian Hu;
Jingyuan Wang;
Weiqiang Lu;
Jin Huang

Publication type:

Article

BDMC33, A Curcumin Derivative Suppresses Inflammatory Responses in Macrophage-Like Cellular System: Role of Inhibition in NF-κB and MAPK Signaling Pathways.

Published in:

International Journal of Molecular Sciences, 2012, v. 13, n. 3, p. 2985, doi. 10.3390/ijms13032985

By:

Ka-Heng Lee;
Yuh-Lit Chow;
Sharmili, Vidyadaran;
Abas, Faridah;
Alitheen, Noorjahan Banu Mohamed;
Shaari, Khozirah;
Israf, Daud Ahmad;
Lajis, Nordin Haji;
Syahida, Ahmad

Publication type:

Article

Identification of novel inhibitors of mitogen-activated protein kinase phosphatase-1 with structure-based virtual screening.

Published in:

Journal of Computer-Aided Molecular Design, 2011, v. 25, n. 5, p. 469, doi. 10.1007/s10822-011-9432-2

By:

Park, Hwangseo;
Jeon, Jeong-Yi;
Kim, Song;
Jeong, Dae;
Ryu, Seong

Publication type:

Article

Prediction of Mechanosensitive Genes in Vascular Endothelial Cells Under High Wall Shear Stress.

Published in:

Frontiers in Genetics, 2022, v. 12, p. 1, doi. 10.3389/fgene.2021.796812

By:

Shen, Lei;
Zhou, Kaige;
Liu, Hong;
Yang, Jie;
Huang, Shuqi;
Yu, Fei;
Huang, Dongya

Publication type:

Article

Prediction of Mechanosensitive Genes in Vascular Endothelial Cells Under High Wall Shear Stress.

Published in:

Frontiers in Genetics, 2022, v. 12, p. 1, doi. 10.3389/fgene.2021.796812

By:

Shen, Lei;
Zhou, Kaige;
Liu, Hong;
Yang, Jie;
Huang, Shuqi;
Yu, Fei;
Huang, Dongya

Publication type:

Article