Works matching DE "DUAL specificity phosphatase 1"

Results: 138

The pseudokinase domain of JAK2 is a dual-specificity protein kinase that negatively regulates cytokine signaling.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 9, p. 971, doi. 10.1038/nsmb.2099

By:

Ungureanu, Daniela;
Jinhua Wu;
Pekkala, Tuija;
Niranjan, Yashavanthi;
Young, Clifford;
Jensen, Ole N.;
Chong-Feng Xu;
Neubert, Thomas A.;
Skoda, Radek C.;
Hubbard, Stevan R.;
Silvennoinen, Olli

Publication type:

Article

Retinoic acid ameliorates rheumatoid arthritis by attenuating inflammation and modulating macrophage polarization through MKP-1/MAPK signaling pathway.

Published in:

Korean Journal of Physiology & Pharmacology, 2025, v. 29, n. 1, p. 45, doi. 10.4196/kjpp.24.079

By:

Mengyuan Xin;
Hangyu Jin;
Xiangyu Guo;
Liang Zhao;
Xiangdan Li;
Dongyuan Xu;
Long Zheng;
Lan Liu

Publication type:

Article

MKP-1 overexpression is associated with chemoresistance in bladder cancer via the MAPK pathway.

Published in:

Oncology Letters, 2020, v. 20, n. 2, p. 1743, doi. 10.3892/ol.2020.11741

By:

Lei, Siyu;
Xu, Hong;
Chen, Naiwen;
Pan, Huan;
Xie, Wenhua;
He, Yi;
Jin, Jing

Publication type:

Article

Tumor necrosis factor α-induced protein 8-like 1 promotes apoptosis by regulating B-cell leukemia/lymphoma-2 family proteins in RAW264.7 cells.

Published in:

Oncology Letters, 2016, v. 12, n. 5, p. 3506, doi. 10.3892/ol.2016.5090

By:

YINAN WANG;
YAO LIU;
CHUNFANG HU;
XIAOYAN NI;
XIAOBO HUANG

Publication type:

Article

Eupatilin induces human renal cancer cell apoptosis via ROS-mediated MAPK and PI3K/AKT signaling pathways.

Published in:

Oncology Letters, 2016, v. 12, n. 4, p. 2894, doi. 10.3892/ol.2016.4989

By:

WEI-FENG ZHONG;
XIAO-HONG WANG;
BIN PAN;
FENG LI;
LU KUANG;
ZE-XUAN SU

Publication type:

Article

miRNA limits MAP kinase-mediated immunity: optimization of plant fitness.

Published in:

Journal of Experimental Botany, 2017, v. 68, n. 21/22, p. 5685, doi. 10.1093/jxb/erx385

By:

Shengjun Li;
Bin Yu

Publication type:

Article

Effect of miR-101 on the Proliferation and Apoptosis of Goat Hair Follicle Stem Cells.

Published in:

Genes, 2022, v. 13, n. 6, p. 1035, doi. 10.3390/genes13061035

By:

Qu, Jingwen;
Wu, Xi;
Wang, Qiang;
Wang, Jian;
Sun, Xiaomei;
Ji, Dejun;
Li, Yongjun

Publication type:

Article

Interaction between the transmembrane domains of Sho1 and Opy2 enhances the signaling efficiency of the Hog1 MAP kinase cascade in Saccharomyces cerevisiae.

Published in:

PLoS ONE, 2019, v. 14, n. 1, p. 1, doi. 10.1371/journal.pone.0211380

By:

Takayama, Tomomi;
Yamamoto, Katsuyoshi;
Saito, Haruo;
Tatebayashi, Kazuo

Publication type:

Article

The p38 mitogen activated protein kinase inhibitor losmapimod in chronic obstructive pulmonary disease patients with systemic inflammation, stratified by fibrinogen: A randomised double-blind placebo-controlled trial.

Published in:

PLoS ONE, 2018, v. 13, n. 3, p. 1, doi. 10.1371/journal.pone.0194197

By:

Fisk, Marie;
Cheriyan, Joseph;
Mohan, Divya;
Forman, Julia;
Mäki-Petäjä, Kaisa M.;
McEniery, Carmel M.;
Fuld, Jonathan;
Rudd, James H. F.;
Hopkinson, Nicholas S.;
Lomas, David A.;
Cockcroft, John R.;
Tal-Singer, Ruth;
Polkey, Michael I.;
Wilkinson, Ian B.

Publication type:

Article

Activation of AMPKα2 in adipocytes is essential for nicotine-induced insulin resistance in vivo.

Published in:

Nature Medicine, 2015, v. 21, n. 4, p. 373, doi. 10.1038/nm.3826

By:

Wu, Yue;
Song, Ping;
Zhang, Wencheng;
Liu, Junhui;
Dai, Xiaoyan;
Liu, Zhaoyu;
Lu, Qiulun;
Ouyang, Changhan;
Xie, Zhonglin;
Zhao, Zhengxing;
Zhuo, Xiaozhen;
Viollet, Benoit;
Foretz, Marc;
Wu, Jiliang;
Yuan, Zuyi;
Zou, Ming-Hui

Publication type:

Article

HSPA1A inhibits pyroptosis and neuroinflammation after spinal cord injury via DUSP1 inhibition of the MAPK signaling pathway.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01086-9

By:

He, Xuegang;
Deng, Bo;
Zhang, Cangyu;
Zhang, Guangzhi;
Yang, Fengguang;
Zhu, Daxue;
Yang, Yong;
Ma, Bing;
Hu, Xuchang;
Wang, Yonggang;
Kang, Xuewen

Publication type:

Article

Canagliflozin protects against sepsis capillary leak syndrome by activating endothelial α1AMPK.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-93156-1

By:

Angé, Marine;
De Poortere, Julien;
Ginion, Audrey;
Battault, Sylvain;
Dechamps, Mélanie;
Muccioli, Giulio G.;
Roumain, Martin;
Morelle, Johann;
Druart, Sébastien;
Mathivet, Thomas;
Bertrand, Luc;
Castanares-Zapatero, Diego;
Horman, Sandrine;
Beauloye, Christophe

Publication type:

Article

Molecular docking and dynamic studies of human growth factor receptor-bound protein (Grb) 2 insights to identify novel inhibitors.

Published in:

Journal of Clinical & Scientific Research, 2016, v. 5, n. 4, p. 252, doi. 10.15380/2277-5706.JCSR.16.07.006

By:

Swargam, Sandeep;
Kanipakam, Hema;
Pradeep, Natrajan;
Suchitra, M. M.;
Rajeswari, J.;
Umamaheswari, A.

Publication type:

Article

Bioinformatic analysis reveals novel hub genes and pathways associated with hypertensive nephropathy.

Published in:

Nephrology, 2019, v. 24, n. 11, p. 1103, doi. 10.1111/nep.13508

By:

Chen, Xiaolei;
Cao, Yiling;
Wang, Zheng;
Zhang, Dongmei;
Tang, Wanxin

Publication type:

Article

MKP1 phosphatase is recruited by CXCL12 in glioblastoma cells and plays a role in DNA strand breaks repair.

Published in:

Carcinogenesis, 2020, v. 41, n. 4, p. 417, doi. 10.1093/carcin/bgz151

By:

Dedobbeleer, Matthias;
Willems, Estelle;
Lambert, Jeremy;
Lombard, Arnaud;
Digregorio, Marina;
Lumapat, Paul Noel;
Valentin, Emmanuel Di;
Freeman, Stephen;
Goffart, Nicolas;
Scholtes, Felix;
Rogister, Bernard

Publication type:

Article

A structural exposé of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-29673-y

By:

Wang, Huanchen;
Perera, Lalith;
Jork, Nikolaus;
Zong, Guangning;
Riley, Andrew M.;
Potter, Barry V. L.;
Jessen, Henning J.;
Shears, Stephen B.

Publication type:

Article

Osmotic-Adaptation Response of sakA/hogA Gene to Aflatoxin Biosynthesis, Morphology Development and Pathogenicity in Aspergillus flavus.

Published in:

Toxins, 2019, v. 11, n. 1, p. 41, doi. 10.3390/toxins11010041

By:

Tumukunde, Elisabeth;
Li, Ding;
Qin, Ling;
Li, Yu;
Shen, Jiaojiao;
Wang, Shihua;
Yuan, Jun

Publication type:

Article

The Pore-Forming α-Toxin from Clostridium septicum Activates the MAPK Pathway in a Ras-c-Raf-Dependent and Independent Manner.

Published in:

Toxins, 2015, v. 7, n. 2, p. 516, doi. 10.3390/toxins7020516

By:

Chakravorty, Anjana;
Awad, Milena M.;
Cheung, Jackie K.;
Hiscox, Thomas J.;
Lyras, Dena;
Rood, Julian I.

Publication type:

Article

p38δ MAPK: Emerging Roles of a Neglected Isoform.

Published in:

International Journal of Cell Biology, 2014, p. 1, doi. 10.1155/2014/272689

By:

O'Callaghan, Carol;
Fanning, Liam J.;
Barry, Orla P.

Publication type:

Article

Zinc-Finger Nuclease Knockout of Dual-Specificity Protein Phosphatase-5 Enhances the Myogenic Response and Autoregulation of Cerebral Blood Flow in FHH.1BN Rats.

Published in:

PLoS ONE, 2014, v. 9, n. 11, p. 1, doi. 10.1371/journal.pone.0112878

By:

Fan, Fan;
Geurts, Aron M.;
Pabbidi, Mallikarjuna R.;
Smith, Stanley V.;
Harder, David R.;
Jacob, Howard;
Roman, Richard J.

Publication type:

Article

Cholesterol Selectively Regulates IL-5 Induced Mitogen Activated Protein Kinase Signaling in Human Eosinophils.

Published in:

PLoS ONE, 2014, v. 9, n. 8, p. 1, doi. 10.1371/journal.pone.0103122

By:

Burnham, Mandy E.;
Esnault, Stephane;
Roti Roti, Elon C.;
Bates, Mary E.;
Bertics, Paul J.;
Denlinger, Loren C.

Publication type:

Article

Nitric Oxide Affects ERK Signaling through Down-Regulation of MAP Kinase Phosphatase Levels during Larval Development of the Ascidian Ciona intestinalis.

Published in:

PLoS ONE, 2014, v. 9, n. 7, p. 1, doi. 10.1371/journal.pone.0102907

By:

Castellano, Immacolata;
Ercolesi, Elena;
Palumbo, Anna

Publication type:

Article

Rice Mitogen Activated Protein Kinase Kinase and Mitogen Activated Protein Kinase Interaction Network Revealed by In-Silico Docking and Yeast Two-Hybrid Approaches

Published in:

PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0065011

By:

Wankhede, Dhammaprakash Pandhari;
Misra, Mohit;
Singh, Pallavi;
Sinha, Alok Krishna

Publication type:

Article

Transcriptional Regulation of Human Dual Specificity Protein Phosphatase 1 (DUSP1) Gene by Glucocorticoids.

Published in:

PLoS ONE, 2010, v. 5, n. 10, p. 1, doi. 10.1371/journal.pone.0013754

By:

Shipp, Lauren E.;
Lee, Joyce V.;
Chi-Yi Yu;
Pufall, Miles;
Pili Zhang;
Scott, Donald K.;
Jen-Chywan Wang

Publication type:

Article

Coexpression of human somatostatin receptor-2 (SSTR2) and SSTR3 modulates antiproliferative signaling and apoptosis.

Published in:: Journal of Molecular Signaling, 2012, v. 7, n. 1, p. 5, doi. 10.1186/1750-2187-7-5
Publication type:: Article

MicroRNA-708 regulates CD38 expression through signaling pathways JNK MAP kinase and PTEN/ AKT in human airway smooth muscle cells.

Published in:

Respiratory Research, 2014, v. 15, n. 8, p. 1, doi. 10.1186/s12931-014-0107-0

By:

Dileepan, Mythili;
Jude, Joseph A.;
Rao, Savita P.;
Walseth, Timothy F.;
Panettieri Jr., Reynold A.;
Subramanian, Subbaya;
Kannan, Mathur S.

Publication type:

Article

Calpain-2 promotes MKP-1 expression protecting cardiomyocytes in both in vitro and in vivo mouse models of doxorubicin-induced cardiotoxicity.

Published in:

Archives of Toxicology, 2019, v. 93, n. 4, p. 1051, doi. 10.1007/s00204-019-02405-w

By:

Zhang, Yi;
Zheng, Dong;
Ni, Rui;
Peng, Tianqing;
Su, Zhaoliang;
Fan, Guo-Chang;
Robbins, Jeffrey;
Song, Long-Sheng;
Li, Jianmin

Publication type:

Article

Activation of the ERK1/2 Mitogen-Activated Protein Kinase Cascade by Dentin Matrix Protein 1 Promotes Osteoblast Differentiation.

Published in:

Cells Tissues Organs, 2011, v. 194, n. 2-4, p. 255, doi. 10.1159/000324258

By:

Eapen, Asha;
Ramachandran, Amsaveni;
Pratap, Jitesh;
George, Anne

Publication type:

Article

Ulinastatin attenuates diabetes-induced cardiac dysfunction by the inhibition of inflammation and apoptosis.

Published in:

Experimental & Therapeutic Medicine, 2017, v. 14, n. 3, p. 2497, doi. 10.3892/etm.2017.4824

By:

WEN-KE WANG;
QING-HUA LU;
XIN WANG;
BEN WANG;
JUAN WANG;
HUI-PING GONG;
LIN WANG;
HAO LI;
YI-MENG DU

Publication type:

Article

Astrocyte ERK phosphorylation precedes K.

Published in:

Neuropathology, 2011, v. 31, n. 3, p. 250, doi. 10.1111/j.1440-1789.2010.01172.x

By:

Liping Cai;
Ting Du;
Dan Song;
Baoman Li;
Hertz, Leif;
Liang Peng

Publication type:

Article

Construction of a novel circRNA-miRNA-ferroptosis related mRNA network in ischemic stroke.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-41028-1

By:

Xie, Huirong;
Huang, Yijie;
Zhan, Yanli

Publication type:

Article

Role of MKP-1 (DUSP1) in clozapine-induced effects on the ERK1/2 signaling pathway in the rat frontal cortex.

Published in:

Psychopharmacology, 2013, v. 230, n. 3, p. 425, doi. 10.1007/s00213-013-3165-y

By:

Kim, Se Hyun;
Yu, Hyun Sook;
Park, Hong Geun;
Park, Soyoung;
Seo, Myoung Suk;
Jeon, Won Je;
Ahn, Yong Min;
Ha, Kyooseob;
Shin, Soon Young;
Kim, Yong Sik

Publication type:

Article

Rosiglitazone Improves Glucocorticoid Resistance in a Sudden Sensorineural Hearing Loss by Promoting MAP Kinase Phosphatase-1 Expression.

Published in:

Mediators of Inflammation, 2019, p. 1, doi. 10.1155/2019/7915730

By:

Xia, Liang;
Liu, Jingjing;
Sun, Yuanyuan;
Shi, Haibo;
Yang, Guang;
Feng, Yanmei;
Yin, Shankai

Publication type:

Article

Association of oligodendrocytes differentiation regulator gene DUSP15 with autism.

Published in:

World Journal of Biological Psychiatry, 2017, v. 18, n. 2, p. 143, doi. 10.1080/15622975.2016.1178395

By:

Tian, Ye;
Wang, Lifang;
Jia, Meixiang;
Lu, Tianlan;
Ruan, Yanyan;
Wu, Zhiliu;
Wang, Linyan;
Liu, Jing;
Zhang, Dai

Publication type:

Article

MAP Kinase Phosphatase 1 (MKP-1/DUSP1) Is Neuroprotective in Huntington's Disease via Additive Effects of JNK and p38 Inhibition.

Published in:

Journal of Neuroscience, 2013, v. 33, n. 6, p. 2213, doi. 10.1523/JNEUROSCI.4965-11.2013

By:

Taylor, David M.;
Moser, Roger;
Régulier, Etienne;
Breuillaud, Lionel;
Dixon, Meredith;
Beesen, Ayshe Ana;
Elliston, Linda;
de Fatima Silva Santos, Mariana;
Kim, Jinho;
Jones, Lesley;
Goldstein, Darlene R.;
Ferrante, Robert J.;
Luthi-Carter, Ruth

Publication type:

Article

The whole genome sequence of Coxsackievirus B3 MKP strain leading to myocarditis and its molecular phylogenetic analysis.

Published in:

Virology Journal, 2014, v. 11, n. 1, p. 1, doi. 10.1186/1743-422X-11-33

By:

Bin Liu;
Zhe Li;
Fengyang Xiang;
Fan Li;
Yang Zheng;
Guoqing Wang

Publication type:

Article

Glucocorticoid receptor dimerization induces MKP1 to protect against TNF-induced inflammation.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 6, p. 2130, doi. 10.1172/JCI60006

By:

Vandevyver, Sofie;
Dejager, Lien;
Bogaert, Tom Van;
Kleyman, Anna;
Liu, Yusen;
Tuckermann, Jan;
Libert, Claude

Publication type:

Article

ANGPTL2 aggravates doxorubicin-induced cardiotoxicity via inhibiting DUSP1 pathway.

Published in:

Bioscience, Biotechnology & Biochemistry, 2022, v. 86, n. 12, p. 1631, doi. 10.1093/bbb/zbac156

By:

Cheng Liu;
Qiuling Chen;
Huadong Liu

Publication type:

Article

Renal tubular gene biomarkers identification based on immune infiltrates in focal segmental glomerulosclerosis.

Published in:

Renal Failure, 2022, v. 44, n. 1, p. 966, doi. 10.1080/0886022X.2022.2081579

By:

Bai, JunYuan;
Pu, XiaoWei;
Zhang, YunXia;
Dai, Enlai

Publication type:

Article

The role of deubiquitinases in cardiac disease.

Published in:: Expert Reviews in Molecular Medicine, 2024, v. 26, p. 1, doi. 10.1017/erm.2024.2
Publication type:: Article

Regulation of tristetraprolin expression by mitogen-activated protein kinase phosphatase-1.

Published in:

APMIS, 2012, v. 120, n. 12, p. 988, doi. 10.1111/j.1600-0463.2012.02927.x

By:

Huotari, Noora;
Hömmö, Tuija;
Taimi, Ville;
Nieminen, Riina;
Moilanen, Eeva;
Korhonen, Riku

Publication type:

Article

Structural and Dynamic Features of F-recruitment Site Driven Substrate Phosphorylation by ERK2.

Published in:

Scientific Reports, 2015, p. 11127, doi. 10.1038/srep11127

By:

Piserchio, Andrea;
Ramakrishan, Venkatesh;
Wang, Hsin;
Kaoud, Tamer S.;
Arshava, Boris;
Dutta, Kaushik;
Dalby, Kevin N.;
Ghose, Ranajeet

Publication type:

Article

Prediction of Mechanosensitive Genes in Vascular Endothelial Cells Under High Wall Shear Stress.

Published in:

Frontiers in Genetics, 2022, v. 12, p. 1, doi. 10.3389/fgene.2021.796812

By:

Shen, Lei;
Zhou, Kaige;
Liu, Hong;
Yang, Jie;
Huang, Shuqi;
Yu, Fei;
Huang, Dongya

Publication type:

Article

Prediction of Mechanosensitive Genes in Vascular Endothelial Cells Under High Wall Shear Stress.

Published in:

Frontiers in Genetics, 2022, v. 12, p. 1, doi. 10.3389/fgene.2021.796812

By:

Shen, Lei;
Zhou, Kaige;
Liu, Hong;
Yang, Jie;
Huang, Shuqi;
Yu, Fei;
Huang, Dongya

Publication type:

Article

Arabidopsis MAP kinase phosphatase 1 and its target MAP kinases 3 and 6 antagonistically determine UV-B stress tolerance, independent of the UVR8 photoreceptor pathway.

Published in:

Plant Journal, 2011, v. 68, n. 4, p. 727, doi. 10.1111/j.1365-313X.2011.04725.x

By:

Besteiro, Marina A. González;
Bartels, Sebastian;
Albert, Andreas;
Ulm, Roman

Publication type:

Article

The MAP kinase phosphatase MKP-1 regulates BDNF-induced axon branching.

Published in:

Nature Neuroscience, 2010, v. 13, n. 11, p. 1373, doi. 10.1038/nn.2655

By:

Jeanneteau, Freddy;
Deinhardt, Katrin;
Miyoshi, Goichi;
Bennett, Anton M;
Chao, Moses V

Publication type:

Article

Identification of single nucleotide polymorphisms of PIK3R1 and DUSP1 genes and their genetic associations with milk production traits in dairy cows.

Published in:

Journal of Animal Science & Biotechnology, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1186/s40104-019-0392-z

By:

Han, Bo;
Yuan, Yuwei;
Shi, Lijun;
Li, Yanhua;
Liu, Lin;
Sun, Dongxiao

Publication type:

Article

M2 macrophage‐derived exosomal miR‐25‐3p improves high glucose‐induced podocytes injury through activation autophagy via inhibiting DUSP1 expression.

Published in:

IUBMB Life, 2020, v. 72, n. 12, p. 2651, doi. 10.1002/iub.2393

By:

Huang, Haihua;
Liu, Huiyun;
Tang, Jiazhen;
Xu, Wenqiong;
Gan, Huaxia;
Fan, Qiwei;
Zhang, Wei

Publication type:

Article

Linalool prevents oxidative stress activated protein kinases in single UVB-exposed human skin cells.

Published in:

PLoS ONE, 2017, v. 12, n. 5, p. 1, doi. 10.1371/journal.pone.0176699

By:

Gunaseelan, Srithar;
Balupillai, Agilan;
Govindasamy, Kanimozhi;
Ramasamy, Karthikeyan;
Muthusamy, Ganesan;
Shanmugam, Mohana;
Thangaiyan, Radhiga;
Robert, Beaulah Mary;
Prasad Nagarajan, Rajendra;
Ponniresan, Veeramani Kandan;
Rathinaraj, Pierson

Publication type:

Article

Sampling-based Bayesian approaches reveal the importance of quasi-bistable behavior in cellular decision processes on the example of the MAPK signaling pathway in PC-12 cell lines.

Published in:

BMC Systems Biology, 2017, v. 11, p. 1, doi. 10.1186/s12918-017-0392-6

By:

Jensch, Antje;
Thomaseth, Caterina;
Radde, Nicole E.

Publication type:

Article