Works matching DE "DRUG resistance in cancer cells"

Results: 5000

Hypoxia- and lactate metabolism-associated prognostic and therapeutic signature in pancreatic cancer.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02873-w

By:

Zhang, Chen-Hui;
Huang, An-Qi;
Shi, Cang-Chang;
Jiang, Zhi-Jia;
Yao, Hao;
Sun, Jin-Jin

Publication type:

Article

Lestaurtinib's antineoplastic activity converges on JAK/STAT signaling to inhibit treatment naïve and therapy resistant forms ovarian cancer.

Published in:

NPJ Precision Oncology, 2025, v. 9, n. 1, p. 1, doi. 10.1038/s41698-025-00947-0

By:

Rodman, Esther P. B.;
Emch, Michael J.;
Hou, Xiaonan;
Bajaj, Archit;
Pearson, Nicole A.;
John, August J.;
Ortiz, Yamillie;
Bass, Adam D.;
Singh, Saloni;
Baldassarre, Gustavo;
Kaufmann, Scott H.;
Weroha, S. John;
Hawse, John R.

Publication type:

Article

Recent Advances in Immunotherapy for Melanoma: Perspectives on the Development of Novel Treatments: A Mini Review.

Published in:

Cancers, 2025, v. 17, n. 13, p. 2265, doi. 10.3390/cancers17132265

By:

Muto, Yusuke;
Fujimura, Taku;
Asano, Yoshihide

Publication type:

Article

Myeloid-Derived Suppressor Cells (MDSCs) at the Crossroad of Senescence and Cancer.

Published in:

Cancers, 2025, v. 17, n. 13, p. 2251, doi. 10.3390/cancers17132251

By:

Talarico, Giovanna;
Orecchioni, Stefania;
Falvo, Paolo;
Bertolini, Francesco

Publication type:

Article

Emerging Techniques of Translational Research in Immuno-Oncology: A Focus on Non-Small Cell Lung Cancer.

Published in:

Cancers, 2025, v. 17, n. 13, p. 2244, doi. 10.3390/cancers17132244

By:

Guardamagna, Mora;
Zamorano, Eduardo;
Albarrán-Artahona, Victor;
Mesas, Andres;
Benitez, Jose Carlos

Publication type:

Article

Role of Human Microbiome in Development and Management of Head and Neck Squamous Cell Carcinoma.

Published in:

Cancers, 2025, v. 17, n. 13, p. 2238, doi. 10.3390/cancers17132238

By:

Palkovsky, Martin;
Modrackova, Nikol;
Neuzil-Bunesova, Vera;
Liberko, Marian;
Hlodakova, Alzbeta;
Soumarova, Renata

Publication type:

Article

The PI3K/Akt/mTOR Signaling Pathway in Triple-Negative Breast Cancer: A Resistance Pathway and a Prime Target for Targeted Therapies.

Published in:

Cancers, 2025, v. 17, n. 13, p. 2232, doi. 10.3390/cancers17132232

By:

Hassan, Ali;
Aubel, Corinne

Publication type:

Article

Current Landscape of Preclinical Models for Pediatric Gliomas: Clinical Implications and Future Directions.

Published in:

Cancers, 2025, v. 17, n. 13, p. 2221, doi. 10.3390/cancers17132221

By:

Faisal, Syed M.;
Yadav, Monika;
Gibson, Garrett R.;
Klinestiver, Adora T.;
Sorenson, Ryan M.;
Cantor, Evan;
Ghishan, Maria;
Prensner, John R.;
Franson, Andrea T.;
Ginn, Kevin F.;
Koschmann, Carl;
Yadav, Viveka Nand

Publication type:

Article

Current Status of Multimodal Therapy for Oligometastatic Disease, Induced Oligometastatic Disease, and Oligo-Progressive Disease in EGFR -Mutated Non-Small-Cell Lung Cancer.

Published in:

Cancers, 2025, v. 17, n. 13, p. 2202, doi. 10.3390/cancers17132202

By:

Miyawaki, Taichi;
Kenmotsu, Hirotsugu;
Ko, Ryo;
Oshima, Masaki;
Shukuya, Takehito;
Shikama, Naoto;
Takahashi, Kazuhisa

Publication type:

Article

Correction: Ye et al. The Mechanisms of lncRNA-Mediated Multidrug Resistance and the Clinical Application Prospects of lncRNAs in Breast Cancer. Cancers 2022, 14 , 2101.

Published in:

2025

By:

Ye, Pingting;
Feng, Lei;
Shi, Shuo;
Dong, Chunyan

Publication type:

Correction Notice

Diagnostic and Therapeutic Potential of Selected microRNAs in Colorectal Cancer: A Literature Review.

Published in:

Cancers, 2025, v. 17, n. 13, p. 2135, doi. 10.3390/cancers17132135

By:

Sychowski, Grzegorz;
Romanowicz, Hanna;
Ciesielski, Wojciech;
Hogendorf, Piotr;
Durczyński, Adam;
Smolarz, Beata

Publication type:

Article

Anti-Neoplastic Activity of Estrogen Receptor Beta in Chemoresistant Triple-Negative Breast Cancer.

Published in:

Cancers, 2025, v. 17, n. 13, p. 2132, doi. 10.3390/cancers17132132

By:

Wang, Xiyin;
Emch, Michael J.;
Goetz, Matthew P.;
Hawse, John R.

Publication type:

Article

The Role of Organoids in Advancing Colorectal Cancer Research: Insights and Future Directions.

Published in:

Cancers, 2025, v. 17, n. 13, p. 2129, doi. 10.3390/cancers17132129

By:

Heydari, Zahra;
Devasahayam Arokia Balaya, Rex;
Sarkar, Gobinda;
Boardman, Lisa

Publication type:

Article

High HER2 Intratumoral Heterogeneity Is Resistant to Anti-HER2 Neoadjuvant Chemotherapy in Early Stage and Locally Advanced HER2-Positive Breast Cancer.

Published in:

Cancers, 2025, v. 17, n. 13, p. 2126, doi. 10.3390/cancers17132126

By:

Hatano, Takaaki;
Tanei, Tomonori;
Seno, Shigeto;
Sota, Yoshiaki;
Masunaga, Nanae;
Mishima, Chieko;
Tsukabe, Masami;
Yoshinami, Tetsuhiro;
Miyake, Tomohiro;
Shimoda, Masafumi;
Shimazu, Kenzo

Publication type:

Article

Cancer Stem Cells Connecting to Immunotherapy: Key Insights, Challenges, and Potential Treatment Opportunities.

Published in:

Cancers, 2025, v. 17, n. 13, p. 2100, doi. 10.3390/cancers17132100

By:

Mathan, Sivapar V.;
Singh, Rana P.

Publication type:

Article

Shifting Shapes: The Endothelial-to-Mesenchymal Transition as a Driver for Cancer Progression.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6353, doi. 10.3390/ijms26136353

By:

Giordanengo, Lucia;
Proment, Alessia;
Botta, Virginia;
Picca, Francesca;
Munir, H. M. Waqas;
Tao, Jiahao;
Olivero, Martina;
Taulli, Riccardo;
Bersani, Francesca;
Sangiolo, Dario;
Novello, Silvia;
Scagliotti, Giorgio Vittorio;
Merlini, Alessandra;
Doronzo, Gabriella

Publication type:

Article

Silibinin Anticancer Effects Through the Modulation of the Tumor Immune Microenvironment in Triple-Negative Breast Cancer.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6265, doi. 10.3390/ijms26136265

By:

Mishra, Shubham D.;
Mendonca, Patricia;
Kaur, Sukhmandeep;
Soliman, Karam F. A.

Publication type:

Article

Effectiveness of PROTAC BET Degraders in Combating Cisplatin Resistance in Head and Neck Cancer Cells.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6185, doi. 10.3390/ijms26136185

By:

Luffman, Natalie;
Ahmadinejad, Fereshteh;
Finnegan, Ryan M.;
Raymond, Marissa;
Gewirtz, David A.;
Harada, Hisashi

Publication type:

Article

Establishment of U-87MG Cellular Fibrosis as a Novel in Vitro Model to Analyze Glioblastoma Cells' Sensitivity to Temozolomide.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6121, doi. 10.3390/ijms26136121

By:

Lopardo, Valentina;
Esposito, Roberta Maria;
Pagano Zottola, Antonio C.;
Santoro, Federica;
Grasso, Nicola;
Carotenuto, Alfonso;
Puca, Annibale Alessandro;
Ciaglia, Elena

Publication type:

Article

Tumor-Associated Macrophage in Breast Tumor Microenvironment.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 5973, doi. 10.3390/ijms26135973

By:

Ma, Lingyao;
Jin, Yuexinzi;
Xu, Jian;
Zhang, Jiexin

Publication type:

Article

Aberrations in the glycosylation of receptor tyrosine kinases: A focus on lung adenocarcinoma.

Published in:

CytoJournal, 2025, v. 22, p. 1, doi. 10.25259/Cytojournal_21_2025

By:

Dmitrieva, Anna M.;
Kocak, Ilayda G.;
Meder, Lydia

Publication type:

Article

非编码 RNA 调控铁死亡介导肝细胞癌索拉非尼耐药的研究进展.

Published in:

Practical Oncology Journal, 2025, v. 39, n. 3, p. 256, doi. 10.11904/j.issn.1002-3070.2025.03.012

By:

朱磊;
郝丹丹

Publication type:

Article

长链非编码 RNA 在口腔鳞状细胞癌中的研究进展.

Published in:

Practical Oncology Journal, 2025, v. 39, n. 3, p. 251, doi. 10.11904/j.issn.1002-3070.2025.03.011

By:

武旭;
德乐黑巴特尔;
达林泰;
苏尼特;
刘军

Publication type:

Article

Galectin-9 treatment is cytotoxic for B cell lymphoma by disrupting autophagy.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1601235

By:

Koll, Lisanne;
Lourens, Harm Jan;
Marsman, Glenn;
de Haan, Stan;
Niki, Toshiro;
Huls, Gerwin A.;
Bremer, Edwin;
Wiersma, Valerie R.

Publication type:

Article

The influence of homologous recombination repair on temozolomide chemosensitivity in gliomas.

Published in:

Carcinogenesis, 2025, v. 46, n. 2, p. 1, doi. 10.1093/carcin/bgaf017

By:

Zeng, Biyun;
Shi, Hansen;
Liu, Tiancai;
Tang, Jinjing;
Lin, Juncheng;
Lin, Xiaocong;
Zeng, Tao

Publication type:

Article

Multifaceted role of transgelin isoforms in cancer hallmarks.

Published in:

Carcinogenesis, 2025, v. 46, n. 2, p. 1, doi. 10.1093/carcin/bgaf014

By:

Jimenez, Ana Maria Jimenez;
Haddad, Yazan;
Jemelikova, Vendula;
Adam, Vojtech;
Rodrigo, Miguel Angel Merlos

Publication type:

Article

Chemoresistance and immune evasion in hepatocellular carcinoma: the role of miRNA-425-5p.

Published in:

Carcinogenesis, 2025, v. 46, n. 2, p. 1, doi. 10.1093/carcin/bgaf012

By:

Pan, Xinghe;
Liu, Junliang;
Zhang, Yitong;
Sun, Chenglin;
Li, You

Publication type:

Article

Role of the nucleotide excision repair function of CETN2 in the inhibition of the sensitivity of hepatocellular carcinoma cells to oxaliplatin.

Published in:

Carcinogenesis, 2025, v. 46, n. 2, p. 1, doi. 10.1093/carcin/bgaf003

By:

Tang, Hengcheng;
Zi, Huaduan;
Zhou, Donghu;
Li, Yanmeng;
Li, Xiaojin;
Chen, Zhibin;
Zhu, Qianyu;
Ouyang, Qin;
He, Pingping;
Chen, Sisi;
Li, Yanling;
Long, Jiang;
Huang, Jian

Publication type:

Article

C.2 Dexamethasone induced p57-mediated quiescence contributes to chemotherapy resistance in sonic hedgehog medulloblastoma.

Published in:

2025

By:

Sharma, A;
Purzner, J;
Purzner, T

Publication type:

Abstract

Establishing best practice in the Australian haematology setting for the use of chimeric antigen receptor T‐cell therapy for relapsed and refractory lymphoma.

Published in:

Internal Medicine Journal, 2025, v. 55, p. 4, doi. 10.1111/imj.16544

By:

Dickinson, Michael;
O'Leary, Nicole;
Hamad, Nada;
Cochrane, Tara;
Ho, P. Joy;
Cheah, Chan Y.;
Bishop, David;
Gregory, Gareth P.;
Butler, Jason;
Barraclough, Allison

Publication type:

Article

Extracellular Vesicles in cancer: from isolation and characterization to metastasis, drug resistance, and clinical applications.

Published in:

BMC Cancer, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12885-025-14375-7

By:

Jurj, Ancuta;
Paul, Doru;
Calin, George A.

Publication type:

Article

ITM2A as a potential prognostic marker for triple-negative breast cancer.

Published in:

Journal of Cancer, 2025, v. 16, n. 9, p. 2903, doi. 10.7150/jca.114801

By:

Can Jiang;
Ruixin Feng;
Yongqian Zhao;
Jingting Zhang;
Na Han;
Yuzhu Zhang;
Guang Shu;
Gang Yin;
Maonan Wang

Publication type:

Article

Molecular and phenotypic characterization of 5-FU resistant colorectal cancer cells: toward enrichment of cancer stem cells.

Published in:

Cancer Cell International, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12935-025-03758-2

By:

Babajnai, Amirhesam;
Rahmani, Saeed;
Asadi, Mohammad Jamal;
Gheytanchi, Elmira;
Adibhesami, Glavizh;
Vakhshiteh, Faezeh;
Madjd, Zahra

Publication type:

Article

CircASH1L inhibits ferroptosis and enhances cisplatin resistance by sponging miR-515-5p to regulate cell cycle-related CDCA7/RRM2 in ovarian cancer cells.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1563869

By:

Feng, Lu;
Zou, Xinru;
Tang, Longyu;
Yuan, Yijun;
He, Tianwen;
Su, Bin;
Tang, Ying;
Wang, Jiang;
Liu, Kang;
Li, Jun

Publication type:

Article

Reprogramming of glucose metabolism in pancreatic cancer: mechanisms, implications, and therapeutic perspectives.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1586959

By:

Zhang, Yan;
Li, Wancheng;
Niu, Jubao;
Fan, Zeyang;
Li, Xin;
Zhang, Hui

Publication type:

Article

SIRT5-modified human umbilical cord mesenchymal stem cells loaded with antioxidant polydopamine nanozyme enhance parpi resistance in ovarian cancer via fatty acid metabolism reprogramming.

Published in:

Journal of Nanobiotechnology, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12951-025-03516-6

By:

Zhang, Jin;
Du, Xiuluan;
Dai, Xin;
Liu, Yanxiang;
Guo, Kai;
Gu, Donghua

Publication type:

Article

Nuclear receptor subfamily 1 group D member 2 induces chemoresistance in ovarian cancer by regulating ferroptosis and immune infiltration.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03051-8

By:

Wang, Linlin;
Shao, Ning;
Qu, Yaoyu;
Sun, Huizhen;
Zhao, Jin

Publication type:

Article

OTUB1 promotes colorectal cancer progression by stabilizing GPX4 and inhibiting ferroptosis.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03022-z

By:

Lin, Guofeng;
Lin, Xi;
Lin, Qihuang;
Zhao, Jianfeng

Publication type:

Article

Exosome-Mediated Mechanisms of Drug Resistance in Lung Cancer: Molecular Mechanisms and Therapeutic Strategies.

Published in:

Cellular Physiology & Biochemistry (Cell Physiol Biochem Press GmbH & Co. KG), 2025, v. 59, n. 3, p. 358, doi. 10.33594/000000779

By:

Havryliuk, Vita;
Wojtowicz, Karolina;
Gagat, Maciej;
Żuryń, Agnieszka

Publication type:

Article

CRO-67 has anti-cancer activity in pancreatic tumor cells and stromal cancer-associated fibroblasts.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-09411-2

By:

Chiang, Shannon;
Garcia Netto, Keilah;
Kokkinos, John;
Haghighi, Koroush S.;
Raina, Aparna S.;
Youkhana, Janet;
Pitiyarachchi, Omali;
Truong, Quach;
Wenholz, Daniel;
Wilkinson, John;
Laczka, Olivier;
Li, Xiang;
Aldilla, Vina R.;
Kumar, Naresh;
Goldstein, David;
Sharbeen, George;
Phillips, Phoebe A.

Publication type:

Article

Metabolic alterations driven by LDHA in CD8 + T cells promote immune evasion and therapy resistance in NSCLC.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-87361-5

By:

Wen, Hao;
Zhang, Panpan;
Zhao, Juan;
Liu, Yakui;
Wan, Lei;
Li, Haoran;
Yi, Jun;
Li, Xinqiang

Publication type:

Article

Targeting the FOXA1/BMI1 axis to overcome chemoresistance and suppress tumor progression in nasopharyngeal carcinoma.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02595-6

By:

Qin, Yaping;
Yang, Mingqing;
Cao, Yunzhu;
Fu, Yue;
Yang, Fan;
Zhang, Xiaoling;
Xiao, Shengjun

Publication type:

Article

Tumor‐Specific On‐Site Activation of Cisplatin via Cascade Catalytic‐Redox Reactions for Highly Efficient Chemo‐Immunotherapy.

Published in:

Angewandte Chemie, 2025, v. 137, n. 28, p. 1, doi. 10.1002/ange.202500996

By:

Yang, Gang‐Gang;
Liu, Bin;
Liu, Wei;
Zhang, Lan;
Ke, Can;
Han, Xinya;
Cao, Qian;
Mao, Zong‐Wan

Publication type:

Article

Tripartite motif 47 promotes the development of thyroid carcinoma through ADAR ubiquitination.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01298-z

By:

Liu, Hongzhou;
Hu, Xiaodong;
Li, Tan;
Wang, Yuhan;
Fu, Xiaomin

Publication type:

Article

MCF-7 İnsan Meme Kanseri Hücre Soyunda Doksorubisin Öncesi ve Sonrası GST İzozimlerinin, İlaç Dirençlilik Proteinlerinin ve Apoptotik Etkisinin Araştırılması.

Published in:

Istanbul Gelisim University Journal of Health Sciences / İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi, 2020, n. 10, p. 1, doi. 10.38079/igusabder.631695

By:

KAYA KOÇDOĞAN, Arzu;
OĞUZTÜZÜN, Serpil;
GÜLER ŞİMŞEK, Gülçin;
TÜRK, Mustafa

Publication type:

Article

TRPV1 inhibition sensitizes tumors to PD-1 blockade by reversing resistance to CTL-mediated killing.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-07120-4

By:

Son, Min Kyu;
Lee, Hyo-Jung;
Cho, Eunho;
Oh, Se Jin;
Kim, Tae Woo

Publication type:

Article

Role of epithelial-to-mesenchymal transition and cancer stem cells in colorectal cancer.

Published in:

Oncology in Clinical Practice (2450-1654), 2025, v. 21, n. 3, p. 214, doi. 10.5603/ocp.99669

By:

Fudalej, Marta;
Mormul, Agata;
Deptała, Andrzej;
Badowska-Kozakiewicz, Anna M.

Publication type:

Article

Case Report: Metastatic colorectal cancer with ALK–CEP44 fusion and rapid resistance development.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1613235

By:

Hofmann, Silvan;
Egger, Claudine;
Potthast, Silke;
Zoche, Martin;
Wicki, Andreas;
Mehra, Tarun

Publication type:

Article

Application of single-cell and spatial omics in deciphering cellular hallmarks of cancer drug response and resistance.

Published in:

Journal of Hematology & Oncology, 2025, v. 18, n. 1, p. 1, doi. 10.1186/s13045-025-01722-1

By:

Cheng, Xiaoxia;
Peng, Ting;
Chu, Tian;
Yang, Yiqun;
Liu, Jia;
Gao, Qinglei;
Cao, Canhui;
Wei, Juncheng

Publication type:

Article

Long-term resident adipose-derived stromal stem cells in the microenvironment remodeling BLCA cell stemness and EMT promotes bladder cancer progression.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-07387-7

By:

Huang, Denggao;
Guo, Na;
Peng, Yanling;
Nie, Zhenyu;
Gao, Yuanhui;
Cao, Hui;
Wang, Shunlan;
Chen, Mei;
Wen, Xiaohong;
Wang, Zhaojun;
Zheng, Linlin;
He, Haowei;
Sun, Yong;
Chen, Yang;
Zhang, Shufang

Publication type:

Article