Works matching DE "DRUG metabolism -- Evaluation"

Results: 61

P-glycoprotein plays a role in the oral absorption of BMS-387032, a potent cyclin-dependent kinase 2 inhibitor, in rats.

Published in:

Cancer Chemotherapy & Pharmacology, 2005, v. 55, n. 2, p. 110, doi. 10.1007/s00280-004-0873-3

By:

Kamath, Amrita V.;
Saeho Chong;
Ming Chang;
Marathe, Punit

Publication type:

Article

Clinical manifestations of disturbances in granulopoiesis kinetics: Idiosyncratic agranulocytosis.

Published in:

Archives of Hellenic Medicine / Arheia Ellenikes Iatrikes, 2011, v. 28, n. 4, p. 439

By:

MELETIS, J.;
PAPAGEORGIOU, L.

Publication type:

Article

Metabolic Syndrome in Severe Mental Disorders.

Published in:

Metabolic Syndrome & Related Disorders, 2011, v. 9, n. 2, p. 91, doi. 10.1089/met.2010.0053

By:

Ohaeri, Jude U.;
Akanji, Abayomi O.

Publication type:

Article

Recent Advances in the Clinical Pharmacology of Benzodiazepines Part I: Pharmacokinetics.

Published in:

Human Psychopharmacology: Clinical & Experimental, 1987, v. 2, n. 1, p. 3, doi. 10.1002/hup.470020103

By:

Saletu, B.;
Pakesch, G.

Publication type:

Article

Anti-Mycobacterial Activity of Marine Fungus-Derived 4-Deoxybostrycin and Nigrosporin.

Published in:

Molecules, 2013, v. 18, n. 2, p. 1728, doi. 10.3390/molecules18021728

By:

Cong Wang;
Juan Wang;
Yuhong Huang;
Hong Chen;
Yan Li;
Lili Zhong;
Yi Chen;
Shengping Chen;
Jun Wang;
Juling Kang;
Yi Peng;
Bin Yang;
Yongcheng Lin;
Zhigang She;
Xiaomin Lai

Publication type:

Article

A Critical Appraisal of the Role of Insulin Analogues in the Management of Diabetes Mellitus.

Published in:

Drugs, 2005, v. 65, n. 3, p. 325, doi. 10.2165/00003495-200565030-00003

By:

Oiknine, Ralph;
Bernbaum, Marla;
Mooradian, Arshag D.

Publication type:

Article

Expression of human papillomavirus type 16 E5 protein in amelanotic melanoma cells regulates endo-cellular pH and restores tyrosinase activity.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2009, v. 28, p. 1, doi. 10.1186/1756-9966-28-4

By:

Di Domenico, Fabio;
Foppoli, Cesira;
Blarzino, Carla;
Perluigi, Marzia;
Paolini, Francesca;
Morici, Salvatrice;
Coccia, Raffaella;
Cini, Chiara;
De Marco, Federico

Publication type:

Article

The long, hard road: drug metabolism in the lifetime of the DMDG.

Published in:

Xenobiotica, 2001, v. 31, n. 8/9, p. 459, doi. 10.1080/00498250110052742

By:

Smith, D. A.

Publication type:

Article

Inhibition and induction of human cytochrome P450 (CYP) enzymes.

Published in:

Xenobiotica, 1998, v. 28, n. 12, p. 1203, doi. 10.1080/004982598238886

By:

Pelkonen, O.;
Maenpaa, J.;
Taavitsainen, P.;
Rautio, A.;
Raunio, H.

Publication type:

Article

Spatio-Temporal Simulation of First Pass Drug Perfusion in the Liver.

Published in:

PLoS Computational Biology, 2014, v. 10, n. 3, p. 1, doi. 10.1371/journal.pcbi.1003499

By:

Schwen, Lars Ole;
Krauss, Markus;
Niederalt, Christoph;
Gremse, Felix;
Kiessling, Fabian;
Schenk, Andrea;
Preusser, Tobias;
Kuepfer, Lars

Publication type:

Article

Pharmacogenomics in colorectal carcinomas: Future perspectives in personalized therapyThe authorship is shared equally by Antonio Russo and Simona Corsale.

Published in:

Journal of Cellular Physiology, 2005, v. 204, n. 3, p. 742, doi. 10.1002/jcp.20357

By:

Antonio Russo;
Simona Corsale;
Patrizia Cammareri;
Valentina Agnese;
Sandra Cascio;
Gaetana Di Fede;
Marcella Macaluso;
Viviana Bazan

Publication type:

Article

Induction of macrophage elastase (MMP-12) gene expression by statins.

Published in:

Journal of Cellular Physiology, 2005, v. 204, n. 1, p. 139, doi. 10.1002/jcp.20271

By:

Meltem C. Arikan;
Steven D. Shapiro;
Thomas J. Mariani

Publication type:

Article

Age-related differences in susceptibility to toxic effects of valproic acid in rats.

Published in:

Journal of Applied Toxicology, 2008, v. 28, n. 5, p. 628, doi. 10.1002/jat.1314

By:

Espandiari, Parvaneh;
Zhang, Jun;
Schnackenberg, Laura K.;
Miller, Terry J.;
Knapton, Alan;
Herman, Eugene H.;
Beger, Richard D.;
Hanig, Joseph P.

Publication type:

Article

Propafenone: An Effective Agent for the Management of Supraventricular Arrhythmias.

Published in:

Journal of Cardiovascular Electrophysiology, 1996, v. 7, n. 4, p. 353, doi. 10.1111/j.1540-8167.1996.tb00537.x

By:

Grant, Augustus O.

Publication type:

Article

Therapeutic drug monitoring in neuropsychopharmacology: does it hold its promises?

Published in:

European Archives of Psychiatry & Clinical Neuroscience, 2008, v. 258, p. 21, doi. 10.1007/s00406-007-1005-y

By:

Hiemke, Christoph

Publication type:

Article

NAT Activity in Human Cumulus Cells.

Published in:: Fertility Weekly, 2002, p. 11
Publication type:: Article

Mutual Prodrug Concept: Fundamentals and Applications.

Published in:

Indian Journal of Pharmaceutical Sciences, 2006, v. 68, n. 3, p. 286

By:

Bhosle, D.;
Bharambe, S.;
Gairola, Neha;
Dhaneshwar, Suneela S.

Publication type:

Article

GC-MS and LC-(high-resolution)-MS studies on the metabolic fate and detectability of camfetamine in rat urine.

Published in:

Analytical & Bioanalytical Chemistry, 2014, v. 406, n. 16, p. 3815, doi. 10.1007/s00216-014-7796-6

By:

Welter, Jessica;
Kavanagh, Pierce;
Maurer, Hans

Publication type:

Article

Investigation of the Distribution of Polysaccharides in Polar and Nonpolar Systems and in Various Tissues of the Organism.

Published in:

Pharmaceutical Chemistry Journal, 2004, v. 38, n. 1, p. 31, doi. 10.1023/B:PHAC.0000027642.58599.14

By:

Kaisheva, N. Sh.;
Mykots, L. P.;
Vasilenko, Yu. K.

Publication type:

Article

Critical evaluation of permeation enhancers for oral mucosal drug delivery.

Published in:

Drug Development & Industrial Pharmacy, 2010, v. 36, n. 3, p. 254, doi. 10.3109/03639040903117348

By:

Sohi, Harmik;
Ahuja, Alka;
Ahmad, Farhan Jalees;
Khar, Roop Krishen

Publication type:

Article

Effect of Excipient and Processing Variables on Adhesive Properties and Release Profile of Pentoxifylline From Mucoadhesive Tablets.

Published in:

Drug Development & Industrial Pharmacy, 2006, v. 32, n. 3, p. 377, doi. 10.1080/03639040500519367

By:

Surapaneni, Madhu S.;
Das, Sudip K.;
Das, Nandita G.

Publication type:

Article

The interpretation of hair analysis for drugs and drug metabolites.

Published in:

Clinical Toxicology (15563650), 2018, v. 56, n. 2, p. 90, doi. 10.1080/15563650.2017.1379603

By:

Cuypers, Eva;
Flanagan, Robert J.

Publication type:

Article

Epigenomics and Interindividual Differences in Drug Response.

Published in:

Clinical Pharmacology & Therapeutics, 2012, v. 92, n. 6, p. 727, doi. 10.1038/clpt.2012.152

By:

Ivanov, M;
Kacevska, M;
Ingelman-Sundberg, M

Publication type:

Article

OII-C-2.

Published in:

Clinical Pharmacology & Therapeutics, 2006, v. 79, n. 2, p. P6, doi. 10.1016/j.clpt.2005.12.019

By:

Kennedy, M. J.;
Sullivan, J. E.;
Doll, M. A.;
Griffin, A.;
Hein, D. W.

Publication type:

Article

Substrate Profiling of Glutathione S-transferase with Engineered Enzymes and Matched Glutathione Analogues.

Published in:

Angewandte Chemie, 2014, v. 126, n. 28, p. 7277, doi. 10.1002/ange.201402000

By:

Feng, Shan;
Zhang, Lei;
Adilijiang, Gulishana;
Liu, Jieyuan;
Luo, Minkui;
Deng, Haiteng

Publication type:

Article

Probing the links between in vitro potency, ADMET and physicochemical parameters.

Published in:

2011

By:

Gleeson, M. Paul;
Hersey, Anne;
Montanari, Dino;
Overington, John

Publication type:

journal article

Pharmacogenetics in drug discovery and development: a translational perspective.

Published in:

Nature Reviews Drug Discovery, 2008, v. 7, n. 10, p. 807, doi. 10.1038/nrd2593

By:

Roses, Allen D.

Publication type:

Article

Combinatorial Pharmacogenetics.

Published in:

Nature Reviews Drug Discovery, 2005, v. 4, n. 11, p. 911, doi. 10.1038/nrd1874

By:

Wilke, Russell A.;
Reif, David M.;
Moore, Jason H.

Publication type:

Article

Elucidating mechanisms of drug-induced toxicity.

Published in:

Nature Reviews Drug Discovery, 2005, v. 4, n. 5, p. 410, doi. 10.1038/nrd1720

By:

Liebler, Daniel C.;
Guengerich, F. Peter

Publication type:

Article

Drugs as materials: valuing physical form in drug discovery.

Published in:

Nature Reviews Drug Discovery, 2004, v. 3, n. 11, p. 926, doi. 10.1038/nrd1550

By:

Gardner, Colin R.;
Walsh, Christopher T.;
Almarsson, Örn

Publication type:

Article

Implications of Protein Flexibility for Drug Discovery.

Published in:

Nature Reviews Drug Discovery, 2003, v. 2, n. 7, p. 527, doi. 10.1038/nrd1129

By:

Teague, Simon J.

Publication type:

Article

Comprehensive evaluation of a novel nuclear factor-kappaB inhibitor, quinoclamine, by transcriptomic analysis.

Published in:

2009

By:

Cheng, W.-Y.;
Lien, J.-C.;
Hsiang, C.-Y.;
Wu, S.-L.;
Li, C.-C.;
Lo, H.-Y.;
Chen, J.-C.;
Chiang, S.-Y.;
Liang, J.-A.;
Ho, T.-Y.

Publication type:

journal article

Indapamide Decreases Plasma Adiponectin Concentration in Patients with Essential Hypertension.

Published in:

Kidney & Blood Pressure Research, 2007, v. 30, n. 3, p. 187, doi. 10.1159/000103279

By:

Piecha, Grzegorz;
Adamczak, Marcin;
Chudek, Jerzy;
Wiȩcek, Andrzej

Publication type:

Article

Off-label drug use among hospitalised children: identifying areas with the highest need for research.

Published in:

Pharmacy World & Science, 2008, v. 30, n. 5, p. 497, doi. 10.1007/s11096-008-9193-8

By:

Linda Hsien;
André Breddemann;
Anne-Kristina Frobel;
Andreas Heusch;
Klaus Schmidt;
Stephanie Läer

Publication type:

Article

Commentaries.

Published in:

British Journal of Clinical Pharmacology, 2004, v. 58, n. 7, p. S794, doi. 10.1111/j.1365-2125.2004.02276.x

By:

Kalow, W.

Publication type:

Article

A simple test for acetylator phenotype using caffeine.

Published in:

British Journal of Clinical Pharmacology, 2004, v. 58, n. 7, p. S788, doi. 10.1111/j.1365-2125.2004.02297.x

By:

Grant, D.M.;
Tang, B.K.;
Kalow, W.

Publication type:

Article

Six novel UDP-glucuronosyltransferase (UGT1A3) polymorphisms with varying activity.

Published in:

Journal of Human Genetics, 2004, v. 49, n. 3, p. 123, doi. 10.1007/s10038-003-0119-y

By:

Iwai, Masaru;
Maruo, Yoshihiro;
Ito, Masaki;
Yamamoto, Kazuo;
Sato, Hiroshi;
Takeuchi, Yoshihiro

Publication type:

Article

Metabolism and Ocular Tissue Distribution of an Antiglaucoma Prostanoid, Tafluprost, After Ocular Instillation to Monkeys.

Published in:

Journal of Ocular Pharmacology & Therapeutics, 2011, v. 27, n. 3, p. 251, doi. 10.1089/jop.2010.0178

By:

Fukano, Yasufumi;
Kawazu, Kouichi;
Akaishi, Takahiro;
Bezwada, Padma;
Pellinen, Pertti

Publication type:

Article

Opinion: Gut microorganisms, mammalian metabolism and personalized health care.

Published in:

Nature Reviews Microbiology, 2005, v. 3, n. 5, p. 431, doi. 10.1038/nrmicro1152

By:

Nicholson, Jeremy K.;
Holmes, Elaine;
Wilson, Ian D.

Publication type:

Article

Characterization of oxidative phenotype in a pediatric population of Tlaltizapan, Morelos, Mexico.

Published in:

Acta Pediatrica de Mexico, 2008, v. 29, n. 2, p. 57

By:

Flores-Pérez, Janett;
Juárez-Olguín, Hugo;
Flores-Pérez, Carmen;
Barranco-Garduño, Marcela;
Cruz-Reyes, Irma;
González-Zamora, José Francisco;
Murata, Chiharu;
Castillo-Cruz, Rocío

Publication type:

Article

Differential Effects of Ornithine Enantiomers on the Activity of Anti-oxidant Enzymes, Polyamines Content, and Growth of Tobacco Cells under Osmotic Stresses.

Published in:

Chirality, 2013, v. 25, n. 10, p. 583, doi. 10.1002/chir.22173

By:

Gholami, Morteza;
Ghanati, Faezeh;
Fakhari, Ali Reza;
Yousefzadeh Borojeni, Laleh;
Safari, Masoumeh

Publication type:

Article

The effect of dosing regimen on the pharmacokinetics of risedronate.

Published in:

British Journal of Clinical Pharmacology, 1999, v. 48, n. 4

By:

Mitchell;
Heise;
Pallone;
Clay;
Nesbitt;
Russell;
Melson

Publication type:

Article

Stereoselective pharmacokinetics of ketoprofen and ketoprofen glucuronide in end-stage renal disease: evidence for a ‘futile cycle’ of elimination.

Published in:

British Journal of Clinical Pharmacology, 1999, v. 48, n. 4

By:

Grubb;
Rudy;
Brater;
Hall

Publication type:

Article

Pharmacokinetics and pharmacodynamics of allopurinol in elderly and young subjects.

Published in:

British Journal of Clinical Pharmacology, 1999, v. 48, n. 4

By:

Turnheim;
Krivanek;
Oberbauer

Publication type:

Article

Small animal clinical pharmacology and therapeutics - Edited by DM Booth.

Published in:

2012

By:

Edwards, Scott

Publication type:

Book Review

Considerations and recent advances in QSAR models for cytochrome P450-mediated drug metabolism prediction.

Published in:

Journal of Computer-Aided Molecular Design, 2008, v. 22, n. 11, p. 843, doi. 10.1007/s10822-008-9225-4

By:

Li, Haiyan;
Sun, Jin;
Fan, Xiaowen;
Sui, Xiaofan;
Zhang, Lan;
Wang, Yongjun;
He, Zhonggui

Publication type:

Article

Modeling chemical reactions for drug design.

Published in:

Journal of Computer-Aided Molecular Design, 2007, v. 21, n. 1-3, p. 33, doi. 10.1007/s10822-006-9097-4

By:

Gasteiger, Johann

Publication type:

Article

Maximal Load of the Vitamin B12 Transport System: A Study on Mice Treated for Four Weeks with High-Dose Vitamin B12 or Cobinamide.

Published in:

PLoS ONE, 2012, v. 7, n. 10, p. 1, doi. 10.1371/journal.pone.0046657

By:

Lildballe, Dorte L.;
Mutti, Elena;
Birn, Henrik;
Nexo, Ebba

Publication type:

Article

Absence of Association between N-Acetyltransferase 2 Acetylator Status and Colorectal Cancer Susceptibility: Based on Evidence from 40 Studies.

Published in:

PLoS ONE, 2012, v. 7, n. 3, p. 1, doi. 10.1371/journal.pone.0032425

By:

Lou qian Zhang;
Jian nong Zhou;
Jun Wang;
Guo dong Liang;
Jing ying Li;
Yi dan Zhu;
Yun tao Su

Publication type:

Article

P. falciparum In Vitro Killing Rates Allow to Discriminate between Different Antimalarial Mode-of-Action.

Published in:

PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0030949

By:

Sanz, Laura M.;
Crespo, Benigno;
De-Cózar, Cristina;
Ding, Xavier C.;
Llergo, Jose L.;
Burrows, Jeremy N.;
García-Bustos, Jose F.;
Gamo, Francisco-Javier

Publication type:

Article