Works about DRUG design
Results: 5000
Redefining a new frontier in alkaptonuria therapy with AI-driven drug candidate design via in-silico innovation.
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- Zeitschrift für Naturforschung. Section C: A Journal of Biosciences, 2025, v. 80, n. 3/4, p. 135, doi. 10.1515/znc-2024-0075
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- Article
GNINA 1.3: the next increment in molecular docking with deep learning.
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- Journal of Cheminformatics, 2025, v. 17, n. 1, p. 1, doi. 10.1186/s13321-025-00973-x
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- Article
Core-Extended Naphthalene Diimide Dyads as Light-Up Probes with Targeted Cytotoxicity Toward Tumor Cells.
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- Biomolecules (2218-273X), 2025, v. 15, n. 2, p. 311, doi. 10.3390/biom15020311
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- Article
Advances in the Development of Mitochondrial Pyruvate Carrier Inhibitors for Therapeutic Applications.
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- Biomolecules (2218-273X), 2025, v. 15, n. 2, p. 223, doi. 10.3390/biom15020223
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- Article
Computational Elucidation of a Monobody Targeting the Phosphatase Domain of SHP2.
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- Biomolecules (2218-273X), 2025, v. 15, n. 2, p. 217, doi. 10.3390/biom15020217
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- Article
Improving Identification of Drug-Target Binding Sites Based on Structures of Targets Using Residual Graph Transformer Network.
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- Biomolecules (2218-273X), 2025, v. 15, n. 2, p. 221, doi. 10.3390/biom15020221
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- Article
Quinazolinones as Potential Anticancer Agents: Synthesis and Action Mechanisms.
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- Biomolecules (2218-273X), 2025, v. 15, n. 2, p. 210, doi. 10.3390/biom15020210
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- Article
Identification of Furin Protease Small-Molecule Inhibitor with a 1,3-Thiazol-2-ylaminosulfonyl Scaffold.
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- Pharmaceuticals (14248247), 2025, v. 18, n. 2, p. 273, doi. 10.3390/ph18020273
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- Article
Drug Treatment Direction Based on the Molecular Mechanism of Breast Cancer Brain Metastasis.
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- Pharmaceuticals (14248247), 2025, v. 18, n. 2, p. 262, doi. 10.3390/ph18020262
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- Article
Computational Modeling of Pharmaceuticals with an Emphasis on Crossing the Blood–Brain Barrier.
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- Pharmaceuticals (14248247), 2025, v. 18, n. 2, p. 217, doi. 10.3390/ph18020217
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- Article
Impact of Hydrophobic, Hydrophilic, and Mucus-Binding Motifs on the Therapeutic Potential of Ceftazidime Analogs for Pulmonary Administration.
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- Antibiotics (2079-6382), 2025, v. 14, n. 2, p. 177, doi. 10.3390/antibiotics14020177
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- Article
Multi-Target Profiling of Antioxidant Compounds, Including Repurposing and Combination Strategies.
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- Antioxidants, 2025, v. 14, n. 2, p. 220, doi. 10.3390/antiox14020220
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- Article
The blood–brain barriers: novel nanocarriers for central nervous system diseases.
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- Journal of Nanobiotechnology, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12951-025-03247-8
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- Article
Focus on Glucagon-like Peptide-1 Target: Drugs Approved or Designed to Treat Obesity.
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- International Journal of Molecular Sciences, 2025, v. 26, n. 4, p. 1651, doi. 10.3390/ijms26041651
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- Article
Advances in Antibody-Based Immune-Stimulating Drugs: Driving Innovation in Cancer Therapy.
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- International Journal of Molecular Sciences, 2025, v. 26, n. 4, p. 1440, doi. 10.3390/ijms26041440
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- Article
Investigation of the Anti-Inflammatory and Anti-Oxidant Activities of a Novel Kaempferol-Liposome-Loaded Hydrogel for the Treatment of Acute Eczema.
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- Gels (2310-2861), 2025, v. 11, n. 2, p. 83, doi. 10.3390/gels11020083
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- Article
Ivermectin: Potential Role as Repurposed Drug for COVID-19.
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- Malaysian Journal of Medical Sciences, 2020, v. 27, n. 4, p. 154, doi. 10.21315/mjms2020.27.4.15
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- Article
Drosophila melanogaster: Deciphering Alzheimer's Disease.
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- Malaysian Journal of Medical Sciences, 2017, v. 24, n. 2, p. 6, doi. 10.21315/mjms2017.24.2.2
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- Publication type:
- Article
In Silico Identification of Drug Targets for Antifertility from Natural Products by Differential Reaction Content Analysis of Metabolic Pathways.
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- Malaysian Journal of Medical Sciences, 2011, v. 18, n. 3, p. 13
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- Publication type:
- Article
Trilaciclib for the reduction of chemotherapy-induced myelosuppression in the management of extensive-stage small cell lung cancer: a profile of its use.
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- Drugs & Therapy Perspectives, 2022, v. 38, n. 2, p. 64, doi. 10.1007/s40267-021-00889-0
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- Article
Automated live cell screening system based on a 24-well-microplate with integrated micro fluidics.
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- 2007
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- Publication type:
- journal article
NTU Researchers Make Significant Findings about Protein Architecture.
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- Innovation, 2011, v. 10, n. 1, p. 75
- Publication type:
- Article
Salting-Out Waterborne Catiomeric Polyurethanes for Drugs Encapsulation and Delivery.
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- Macromolecular Chemistry & Physics, 2015, v. 216, n. 19, p. 1914, doi. 10.1002/macp.201500202
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- Publication type:
- Article
Unraveling the Source of Self‐Induced Diastereomeric Anisochronism in Chiral Dipeptides.
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- Chemistry - A European Journal, 2024, v. 30, n. 59, p. 1, doi. 10.1002/chem.202402637
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- Article
Structure‐Based Design of Ultrapotent Tricyclic Ligands for FK506‐Binding Proteins.
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- Chemistry - A European Journal, 2024, v. 30, n. 45, p. 1, doi. 10.1002/chem.202401405
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- Article
Catalytic Asymmetric Synthesis of N−N Biaryl Atropisomers.
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- Chemistry - A European Journal, 2024, v. 30, n. 2, p. 1, doi. 10.1002/chem.202303165
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- Article
Antimalarial Agents Derived from Metal‐Amodiaquine Complexes with Activity in Multiple Stages of the Plasmodium Life Cycle.
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- Chemistry - A European Journal, 2023, v. 29, n. 55, p. 1, doi. 10.1002/chem.202301642
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- Article
Cover Feature: Exploration of N‐Arylation of Backbone Amides as a Novel Tool for Conformational Modification in Peptides (Chem. Eur. J. 40/2023).
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- Chemistry - A European Journal, 2023, v. 29, n. 40, p. 1, doi. 10.1002/chem.202301803
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- Article
A Late-Stage Aryl C--H Olefination Strategy and Its Application Towards Global Proteome Profiling of Δ<sup>8</sup>-Tetrahydrocannabinol.
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- Chemistry - A European Journal, 2023, v. 29, n. 29, p. 1, doi. 10.1002/chem.202300531
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- Article
Atroposelective Nenitzescu Indole Synthesis.
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- Chemistry - A European Journal, 2023, v. 29, n. 25, p. 1, doi. 10.1002/chem.202300279
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- Article
Carbotrifluoromethylations of C−C Multiple Bonds (Excluding Aryl‐ and Alkynyltrifluoromethylations).
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- Chemistry - A European Journal, 2023, v. 29, n. 19, p. 1, doi. 10.1002/chem.202203499
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- Article
Frontispiece: New Opportunities for the Utilization of the Sulfoximine Group in Medicinal Chemistry from the Drug Designer's Perspective.
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- Chemistry - A European Journal, 2022, v. 28, n. 56, p. 1, doi. 10.1002/chem.202285661
- Publication type:
- Article
Optical Modulation of Antibiotic Resistance by Photoswitchable Cystobactamids.
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- Chemistry - A European Journal, 2022, v. 28, n. 54, p. 1, doi. 10.1002/chem.202201297
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- Article
Broad‐Spectrum Antidote Discovery by Untangling the Reactivation Mechanism of Nerve‐Agent‐Inhibited Acetylcholinesterase.
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- Chemistry - A European Journal, 2022, v. 28, n. 40, p. 1, doi. 10.1002/chem.202200678
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- Article
Effect of gem‐Difluorination on the Key Physicochemical Properties Relevant to Medicinal Chemistry: The Case of Functionalized Cycloalkanes.
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- Chemistry - A European Journal, 2022, v. 28, n. 19, p. 1, doi. 10.1002/chem.202200331
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- Article
Photocatalytic Functionalization of Dehydroalanine‐Derived Peptides in Batch and Flow.
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- Angewandte Chemie, 2024, v. 136, n. 19, p. 1, doi. 10.1002/ange.202403271
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- Article
Photocatalytic O‐ to S‐Rearrangement of Tertiary Cyclopropanols.
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- Angewandte Chemie, 2024, v. 136, n. 17, p. 1, doi. 10.1002/ange.202402912
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- Article
Development of a Small Molecule Downmodulator for the Transcription Factor Brachyury.
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- Angewandte Chemie, 2024, v. 136, n. 14, p. 1, doi. 10.1002/ange.202316496
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- Publication type:
- Article
Copper‐Catalyzed C4‐selective Carboxylation of Pyridines with CO<sub>2</sub> via Pyridylphosphonium Salts.
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- Angewandte Chemie, 2024, v. 136, n. 13, p. 1, doi. 10.1002/ange.202318572
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- Article
Carbonyl Olefin Metathesis and Dehydrogenative Cyclization of Aromatic Ketones and gem‐Difluoroalkenes.
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- Angewandte Chemie, 2024, v. 136, n. 5, p. 1, doi. 10.1002/ange.202315269
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- Article
1‐Azaspiro[3.3]heptane as a Bioisostere of Piperidine.
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- Angewandte Chemie, 2023, v. 135, n. 51, p. 1, doi. 10.1002/ange.202311583
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- Publication type:
- Article
Silver‐Catalyzed Dearomative [2π+2σ] Cycloadditions of Indoles with Bicyclobutanes: Access to Indoline Fused Bicyclo[2.1.1]hexanes.
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- Angewandte Chemie, 2023, v. 135, n. 48, p. 1, doi. 10.1002/ange.202310066
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- Article
Organic‐Platinum Hybrids for Covalent Binding of G‐Quadruplexes: Structural Basis and Application to Cancer Immunotherapy.
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- Angewandte Chemie, 2023, v. 135, n. 36, p. 1, doi. 10.1002/ange.202305645
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- Article
Rational Design in Photopharmacology with Molecular Photoswitches.
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- Angewandte Chemie, 2023, v. 135, n. 30, p. 1, doi. 10.1002/ange.202300681
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- Article
Christina Spry.
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- Angewandte Chemie, 2023, v. 135, n. 23, p. 1, doi. 10.1002/ange.202303681
- Publication type:
- Article
Design of Drug Efficacy Guided by Free Energy Simulations of the β<sub>2</sub>‐Adrenoceptor.
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- Angewandte Chemie, 2023, v. 135, n. 22, p. 1, doi. 10.1002/ange.202218959
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- Article
Gold Complexes in Anticancer Therapy: From New Design Principles to Particle‐Based Delivery Systems.
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- Angewandte Chemie, 2023, v. 135, n. 22, p. 1, doi. 10.1002/ange.202218000
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- Article
Chemical Validation of Mycobacterium tuberculosis Phosphopantetheine Adenylyltransferase Using Fragment Linking and CRISPR Interference.
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- Angewandte Chemie, 2023, v. 135, n. 17, p. 1, doi. 10.1002/ange.202300221
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- Article
Amyloid Against Amyloid: Dimeric Amyloid Fragment Ameliorates Cognitive Impairments by Direct Clearance of Oligomers and Plaques.
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- Angewandte Chemie, 2023, v. 135, n. 7, p. 1, doi. 10.1002/ange.202210209
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- Article
Structurally Defined Water‐Soluble Metallofullerene Derivatives towards Biomedical Applications.
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- Angewandte Chemie, 2023, v. 135, n. 3, p. 1, doi. 10.1002/ange.202211704
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- Article