Works matching DE "DOUBLE-strand DNA breaks"

Results: 2228

Ozone Aggravated the Toxicity of Fine Particulate Matter by Impairing Membrane Stability and Facilitating Particle Internalization.

Published in:

Toxics, 2025, v. 13, n. 6, p. 446, doi. 10.3390/toxics13060446

By:

He, Jing;
Wang, Tong;
Li, Han;
Zhou, Yemian;
Liu, Yun;
Xu, An

Publication type:

Article

Mre11 Assembles Linear DNA Fragments into DNA Damage Signaling Complexes.

Published in:

PLoS Biology, 2004, v. 2, n. 5, p. 1, doi. 10.1371/journal.pbio.0020110

By:

Costanzo, Vincenzo;
Paull, Tanya;
Gottesman, Max;
Gautier, Jean

Publication type:

Article

Role of Saccharomyces Single-Stranded DNA-Binding Protein RPA in the Strand Invasion Step of Double-Strand Break Repair.

Published in:

PLoS Biology, 2004, v. 2, n. 1, p. 1, doi. 10.1371/journal.pbio.0020021

By:

Wang, Xuan;
Haber, James E

Publication type:

Article

Efficient RNA interference method by feeding in Brachionus plicatilis (Rotifera).

Published in:

Biotechnology Letters, 2024, v. 46, n. 6, p. 961, doi. 10.1007/s10529-024-03524-w

By:

Zhang, Yu;
Kan, Dongqi;
Zhou, Yang;
Lian, Hairong;
Ge, Lingling;
Shen, Jing;
Dai, Zhongqi;
Shi, Yan;
Han, Cui;
Liu, Xiaojie;
Yang, Jiaxin

Publication type:

Article

Novel CRISPR/Cas9-mediated knockout of LIG4 increases efficiency of site-specific integration in Chinese hamster ovary cell line.

Published in:

Biotechnology Letters, 2022, v. 44, n. 9, p. 1063, doi. 10.1007/s10529-022-03282-7

By:

Wang, Chuanjie;
Sun, Zhaolin;
Wang, Ming;
Jiang, Zhiyang;
Zhang, Mengmeng;
Cao, Hongxu;
Luo, Longlong;
Qiao, Chunxia;
Xiao, He;
Chen, Guojiang;
Li, Xinying;
Liu, Jinqing;
Wei, Zeliang;
Shen, Beifen;
Wang, Jing;
Feng, Jiannan

Publication type:

Article

Adenine base-editing-mediated exon skipping induces gene knockout in cultured pig cells.

Published in:

Biotechnology Letters, 2022, v. 44, n. 1, p. 59, doi. 10.1007/s10529-021-03214-x

By:

Zhu, Xiang-xing;
Pan, Jia-sheng;
Lin, Tao;
Yang, Ye-cheng;
Huang, Qiu-yan;
Yang, Shuai-peng;
Qu, Zi-xiao;
Lin, Zi-sheng;
Wen, Jian-cong;
Yan, Ai-fen;
Feng, Juan;
Liu, Lian;
Zhang, Xiao-li;
Lu, Jia-hong;
Tang, Dong-sheng

Publication type:

Article

Application of the modified cytosine base-editing in the cultured cells of bama minipig.

Published in:

Biotechnology Letters, 2021, v. 43, n. 9, p. 1699, doi. 10.1007/s10529-021-03159-1

By:

Pan, Jia-sheng;
Lin, Zi-sheng;
Wen, Jian-cong;
Guo, Jian-feng;
Wu, Xia-hui;
Liu, Ying-ying;
Lai, Wen-jun;
Liang, Qi-ying;
Xie, Yong-shi;
Chen, Yi-rou;
Chen, Yi-hong;
Yan, Ai-fen;
Feng, Juan;
Liu, Lian;
Gong, Dao-yuan;
Zhu, Xiang-xing;
Lu, Jia-hong;
Tang, Dong-sheng

Publication type:

Article

Rad1 attenuates DNA double-strand breaks and cell cycle arrest in type II alveolar epithelial cells of rats with bronchopulmonary dysplasia.

Published in:

Molecular Medicine, 2023, v. 29, n. 1, p. 1, doi. 10.1186/s10020-023-00660-3

By:

Tong, Xin;
Li, Danni;
Liu, Na;
Huang, Wanjie;
Zhao, Xinyi;
Zhang, Dan;
Xue, Xindong;
Fu, Jianhua

Publication type:

Article

Image Analysis Using Imaris 10.1 Machine Learning to Quantitate γH2AX Foci in U87 Cells.

Published in:

Microscopy & Microanalysis, 2024, v. 30, p. 1, doi. 10.1093/mam/ozae044.201

By:

Planck, Emma;
Teoli, Dominic;
Yasui, Linda

Publication type:

Article

Off-target effects of base editors: what we know and how we can reduce it.

Published in:

Current Genetics, 2022, v. 68, n. 1, p. 39, doi. 10.1007/s00294-021-01211-1

By:

Slesarenko, Yana S.;
Lavrov, Alexander V.;
Smirnikhina, Svetlana A.

Publication type:

Article

Homology length dictates the requirement for Rad51 and Rad52 in gene targeting in the Basidiomycota yeast Naganishia liquefaciens.

Published in:

Current Genetics, 2021, v. 67, n. 6, p. 919, doi. 10.1007/s00294-021-01201-3

By:

Palihati, Maierdan;
Tsubouchi, Hideo;
Argunhan, Bilge;
Kajitani, Rei;
Bakenova, Omirgul;
Han, Yong-Woon;
Murayama, Yasuto;
Itoh, Takehiko;
Iwasaki, Hiroshi

Publication type:

Article

Mutagenicity in haploid yeast meiosis resulting from repair of DSBs by the sister chromatid.

Published in:

Current Genetics, 2021, v. 67, n. 5, p. 799, doi. 10.1007/s00294-021-01189-w

By:

Simchen, Giora;
Mansour, Osama;
Morciano, Liat;
Zenvirth, Drora;
Arbel-Eden, Ayelet

Publication type:

Article

Single-strand template repair: key insights to increase the efficiency of gene editing.

Published in:

Current Genetics, 2021, v. 67, n. 5, p. 747, doi. 10.1007/s00294-021-01186-z

By:

Gallagher, Danielle N.;
Haber, James E.

Publication type:

Article

How do small chromosomes know they are small? Maximizing meiotic break formation on the shortest yeast chromosomes.

Published in:

Current Genetics, 2021, v. 67, n. 3, p. 431, doi. 10.1007/s00294-021-01160-9

By:

Murakami, Hajime;
Mu, Xiaojing;
Keeney, Scott

Publication type:

Article

Budding yeast Rad51: a paradigm for how phosphorylation and intrinsic structural disorder regulate homologous recombination and protein homeostasis.

Published in:

Current Genetics, 2021, v. 67, n. 3, p. 389, doi. 10.1007/s00294-020-01151-2

By:

Woo, Tai-Ting;
Chuang, Chi-Ning;
Wang, Ting-Fang

Publication type:

Article

Single-molecule fluorescence microscopy reveals modulation of DNA polymerase IV-binding lifetimes by UmuD (K97A) and UmuD′.

Published in:

Current Genetics, 2021, v. 67, n. 2, p. 295, doi. 10.1007/s00294-020-01134-3

By:

Henrikus, Sarah S.;
van Oijen, Antoine M.;
Robinson, Andrew

Publication type:

Article

Limiting homologous recombination at stalled replication forks is essential for cell viability: DNA2 to the rescue.

Published in:

Current Genetics, 2020, v. 66, n. 6, p. 1085, doi. 10.1007/s00294-020-01106-7

By:

Appanah, Rowin;
Jones, David;
Falquet, Benoît;
Rass, Ulrich

Publication type:

Article

Emerging non-canonical roles for the Rad51–Rad52 interaction in response to double-strand breaks in yeast.

Published in:

Current Genetics, 2020, v. 66, n. 5, p. 917, doi. 10.1007/s00294-020-01081-z

By:

Ngo, Katrina;
Epum, Esther A.;
Friedman, Katherine L.

Publication type:

Article

Activation of ATR-related protein kinase upon DNA damage recognition.

Published in:

Current Genetics, 2020, v. 66, n. 2, p. 327, doi. 10.1007/s00294-019-01039-w

By:

Ma, Minh;
Rodriguez, Anibian;
Sugimoto, Katsunori

Publication type:

Article

Rejuvenation of ribosomal RNA gene repeats at the nuclear pore.

Published in:

Current Genetics, 2020, v. 66, n. 1, p. 7, doi. 10.1007/s00294-019-01024-3

By:

Horigome, Chihiro;
Kobayashi, Takehiko

Publication type:

Article

Double-strand breaks in motion: implications for chromosomal rearrangement.

Published in:

Current Genetics, 2020, v. 66, n. 1, p. 1, doi. 10.1007/s00294-019-01015-4

By:

Wilson, Thomas E.;
Sunder, Sham

Publication type:

Article

The functional complexity of the RNA-binding protein Yra1: mRNA biogenesis, genome stability and DSB repair.

Published in:

Current Genetics, 2020, v. 66, n. 1, p. 63, doi. 10.1007/s00294-019-01011-8

By:

Infantino, Valentina;
Stutz, Françoise

Publication type:

Article

Moving forward one step back at a time: reversibility during homologous recombination.

Published in:

Current Genetics, 2019, v. 65, n. 6, p. 1333, doi. 10.1007/s00294-019-00995-7

By:

Piazza, Aurèle;
Heyer, Wolf-Dietrich

Publication type:

Article

DksA and DNA double-strand break repair.

Published in:

Current Genetics, 2019, v. 65, n. 6, p. 1297, doi. 10.1007/s00294-019-00983-x

By:

Myka, Kamila K.;
Gottesman, Max E.

Publication type:

Article

Keep moving and stay in a good shape to find your homologous recombination partner.

Published in:

Current Genetics, 2019, v. 65, n. 1, p. 29, doi. 10.1007/s00294-018-0873-1

By:

Bordelet, Hélène;
Dubrana, Karine

Publication type:

Article

Trinucleotide repeat instability during double-strand break repair: from mechanisms to gene therapy.

Published in:

Current Genetics, 2019, v. 65, n. 1, p. 17, doi. 10.1007/s00294-018-0865-1

By:

Mosbach, Valentine;
Poggi, Lucie;
Richard, Guy-Franck

Publication type:

Article

Structure-function relationships of the Mre11 protein in the control of DNA end bridging and processing.

Published in:

Current Genetics, 2019, v. 65, n. 1, p. 11, doi. 10.1007/s00294-018-0861-5

By:

Marsella, Antonio;
Cassani, Corinne;
Casari, Erika;
Tisi, Renata;
Longhese, Maria Pia

Publication type:

Article

Chromatin mobility upon DNA damage: state of the art and remaining questions.

Published in:

Current Genetics, 2019, v. 65, n. 1, p. 1, doi. 10.1007/s00294-018-0852-6

By:

Zimmer, Christophe;
Fabre, Emmanuelle

Publication type:

Article

The conserved histone variant H2A.Z illuminates meiotic recombination initiation.

Published in:

Current Genetics, 2018, v. 64, n. 5, p. 1015, doi. 10.1007/s00294-018-0825-9

By:

Yamada, Shintaro;
Kugou, Kazuto;
Ding, Da-Qiao;
Fujita, Yurika;
Hiraoka, Yasushi;
Murakami, Hiroshi;
Ohta, Kunihiro;
Yamada, Takatomi

Publication type:

Article

Chromosome ends as adaptive beginnings: the potential role of dysfunctional telomeres in subtelomeric evolvability.

Published in:

Current Genetics, 2018, v. 64, n. 5, p. 997, doi. 10.1007/s00294-018-0822-z

By:

Mason, Jennifer M. O.;
McEachern, Michael J.

Publication type:

Article

Oxygen and RNA in stress-induced mutation.

Published in:

Current Genetics, 2018, v. 64, n. 4, p. 769, doi. 10.1007/s00294-017-0801-9

By:

Correa, Raul;
Thornton, Philip C.;
Hastings, P. J.;
Rosenberg, Susan M.

Publication type:

Article

Fumarase is involved in DNA double-strand break resection through a functional interaction with Sae2.

Published in:

Current Genetics, 2018, v. 64, n. 3, p. 697, doi. 10.1007/s00294-017-0786-4

By:

Leshets, Michael;
Ramamurthy, Dharanidharan;
Lisby, Michael;
Lehming, Norbert;
Pines, Ophry

Publication type:

Article

Interaction of the <italic>Saccharomyces cerevisiae</italic> RING-domain protein Nse1 with Nse3 and the Smc5/6 complex is required for chromosome replication and stability.

Published in:

Current Genetics, 2018, v. 64, n. 3, p. 599, doi. 10.1007/s00294-017-0776-6

By:

Wani, Saima;
Maharshi, Neelam;
Kothiwal, Deepash;
Mahendrawada, Lakshmi;
Kalaivani, Raju;
Laloraya, Shikha

Publication type:

Article

Modelling Potential Candidates for Targeted Auger Therapy.

Published in:

Biophysica, 2024, v. 4, n. 4, p. 711, doi. 10.3390/biophysica4040046

By:

Buchanan, Conor M. J.;
Aboagye, Eric O.;
Evitts, Lee J.;
Rushton, Michael J. D.;
Smith, Tim A. D.

Publication type:

Article

Dual Nucleosomal Double-Strand Breaks Are the Key Effectors of Curative Radiation Therapy.

Published in:

Biophysica, 2023, v. 3, n. 4, p. 668, doi. 10.3390/biophysica3040045

By:

Brahme, Anders;
Lorat, Yvonne

Publication type:

Article

Understanding oocyte ageing.

Published in:

Minerva Obstetrics & Gynecology, 2024, v. 76, n. 3, p. 284, doi. 10.23736/S2724-606X.24.05343-0

By:

HOMER, Hayden A.

Publication type:

Article

PLECTRANTHUS: FROM TRADITIONAL MEDICINE TO BRAIN TUMOR THERAPY WITH DITERPENES.

Published in:

Journal of Research in Pharmacy, 2023, v. 27, p. 9, doi. 10.29228/jrp.381

By:

María DOMÍNGUEZ-MARTÍN, Eva;
MAGALHÃES, Mariana;
SITAREK, Przemysław;
María DÍAZ-LANZA, Ana;
GÓMEZ, Ana M.;
EFFERTH, Thomas;
CABRAL, Célia;
RIJO, Patricia

Publication type:

Article

PLECTRANTHUS: FROM TRADITIONAL MEDICINE TO BRAIN TUMOR THERAPY WITH DITERPENES.

Published in:

Journal of Research in Pharmacy, 2023, v. 27, p. 9, doi. 10.29228/jrp.381

By:

DOMÍNGUEZ-MARTÍN, Eva María;
MAGALHÃES, Mariana;
SITAREK, Przemysław;
DÍAZ-LANZA, Ana María;
GÓMEZ, Ana M.;
EFFERTH, Thomas;
CABRAL, Célia;
RIJO, Patricia

Publication type:

Article

Condensin II interacts with BLM helicase in S phase to maintain genome stability.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-07916-0

By:

Rodemoyer, Brian;
Kariyawasam, Ganesha;
Subramanian, Veena;
Schmidt, Kristina

Publication type:

Article

Genomic hallmarks of endocrine therapy resistance in ER/PR+HER2- breast tumours.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-07606-x

By:

Ghosh, Arnab;
Chaubal, Rohan;
Das, Chitrarpita;
Parab, Pallavi;
Das, Subrata;
Maitra, Arindam;
Majumder, Partha P.;
Gupta, Sudeep;
Biswas, Nidhan K.

Publication type:

Article

Toxoplasma gondii infection induces early host cell cycle arrest and DNA damage in primary human host cells by a MYR1-dependent mechanism.

Published in:

Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-07374-0

By:

Velásquez, Zahady D.;
Rojas-Baron, Lisbeth;
Conejeros, Iván;
Hermosilla, Carlos;
Taubert, Anja

Publication type:

Article

Characterization of macrophages associated with human skin models exposed to UV radiation.

Published in:

Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-06975-z

By:

Phuphanitcharoenkun, Suphanun;
Louis, Fiona;
Sowa, Yoshihiro;
Uchida, Kentaro;
Katsuyama, Misa;
Waditee-Sirisattha, Rungaroon;
Kageyama, Hakuto;
Matsusaki, Michiya;
Palaga, Tanapat

Publication type:

Article

The effect of non-thermal plasma Jet on bacterial biofilms and plasmid DNA.

Published in:

Al-Mustansiriyah Journal of Science, 2021, v. 32, n. 5, p. 19, doi. 10.23851/mjs.v32i5.1118

By:

Sulaiman, Saba Mawlood;
Abdulla Sulyman, Safa Aldeen

Publication type:

Article

RNA-guided piggyBac transposition in human cells.

Published in:

Synthetic Biology (23977000), 2019, v. 4, n. 1, p. N.PAG, doi. 10.1093/synbio/ysz018

By:

Hew, Brian E;
Sato, Ryuei;
Mauro, Damiano;
Stoytchev, Ilko;
Owens, Jesse B

Publication type:

Article

An Expansion of the Endoplasmic Reticulum that Halts Autophagy is Permissive to Genome Instability.

Published in:

Contact (25152564), 2023, p. 1, doi. 10.1177/25152564231157706

By:

Lara-Barba, Eliana;
Torán-Vilarrubias, Alba;
Moriel-Carretero, María

Publication type:

Article

PARP4 deficiency enhances sensitivity to ATM inhibitor by impairing DNA damage repair in melanoma.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02296-0

By:

Li, Yuehua;
Liu, Yu;
Ma, Jingjing;
Yang, Yuqi;
Yue, Qiao;
Zhu, Guannan;
Guo, Weinan;
Gao, Tianwen;
Shi, Qiong;
Li, Chunying

Publication type:

Article

DDB2 expression lights the way for precision radiotherapy response in PDAC cells, with or without olaparib.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-02188-9

By:

Dardare, Julie;
Witz, Andréa;
Betz, Margaux;
François, Aurélie;
Lamy, Laureline;
Husson, Marie;
Demange, Jessica;
Rouyer, Marie;
Lambert, Aurélien;
Merlin, Jean-Louis;
Gilson, Pauline;
Harlé, Alexandre

Publication type:

Article

The anti-tumor effect of trifluridine via induction of aberrant mitosis is unaffected by mutations modulating p53 activity.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-02083-3

By:

Wakasa, Takeshi;
Nonaka, Kentaro;
Harada, Akihito;
Ohkawa, Yasuyuki;
Kikutake, Chie;
Suyama, Mikita;
Kobunai, Takashi;
Tsunekuni, Kenta;
Matsuoka, Kazuaki;
Kataoka, Yuki;
Ochiiwa, Hiroaki;
Miyadera, Kazutaka;
Sagara, Takeshi;
Oki, Eiji;
Ohdo, Shigehiro;
Maehara, Yoshihiko;
Iimori, Makoto;
Kitao, Hiroyuki

Publication type:

Article

Inhibition of key DNA double strand break repair protein kinases enhances radiosensitivity of head and neck cancer cells to X-ray and proton irradiation.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-02059-3

By:

Fabbrizi, Maria Rita;
Doggett, Thomas J.;
Hughes, Jonathan R.;
Melia, Emma;
Dufficy, Elizabeth R.;
Hill, Rhianna M.;
Goula, Amalia;
Phoenix, Ben;
Parsons, Jason L.

Publication type:

Article

Unveiling the relationship between WWOX and BRCA1 in mammary tumorigenicity and in DNA repair pathway selection.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-01878-8

By:

Bidany-Mizrahi, Tirza;
Shweiki, Aya;
Maroun, Kian;
Abu-Tair, Lina;
Mali, Bella;
Aqeilan, Rami I.

Publication type:

Article