Works matching DE "DOUBLE-strand DNA breaks"
Results: 2153
AZD7648 (DNA-PKcs inhibitor): a two-edged sword for editing genomes.
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- Functional & Integrative Genomics, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10142-025-01560-x
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- Article
ATP-Dependent Chromatin Remodeler CSB Couples DNA Repair Pathways to Transcription with Implications for Cockayne Syndrome and Cancer Therapy.
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- Cells (2073-4409), 2025, v. 14, n. 4, p. 239, doi. 10.3390/cells14040239
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- Article
The Tight Relationship Between the Tumoral Microenvironment and Radium-223.
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- Biomedicines, 2025, v. 13, n. 2, p. 456, doi. 10.3390/biomedicines13020456
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- Article
Single Low-Dose Ionizing Radiation Transiently Enhances Rat RIN-m5F Cell Function via the ROS/p38 MAPK Pathway Without Inducing Cell Damage.
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- Antioxidants, 2025, v. 14, n. 2, p. 120, doi. 10.3390/antiox14020120
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- Article
Characterization of PRDM9 Multifunctionality in Yak Testes Through Protein Interaction Mapping.
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- International Journal of Molecular Sciences, 2025, v. 26, n. 4, p. 1420, doi. 10.3390/ijms26041420
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- Article
PRDM9 drives the location and rapid evolution of recombination hotspots in salmonid fish.
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- PLoS Biology, 2025, v. 23, n. 1, p. 1, doi. 10.1371/journal.pbio.3002950
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- Article
Wnt signaling modulates the response to DNA damage in the Drosophila wing imaginal disc by regulating the EGFR pathway.
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- PLoS Biology, 2024, v. 22, n. 7, p. 1, doi. 10.1371/journal.pbio.3002547
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- Article
The canine RAD51 mutation leads to the attenuation of interaction with PALB2.
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- Veterinary & Comparative Oncology, 2020, v. 18, n. 2, p. 247, doi. 10.1111/vco.12542
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- Article
The Rapid Synthesis of Colibactin Warhead Model Compounds Using New Metal‐Free Photocatalytic Cyclopropanation Reactions Facilitates the Investigation of Biological Mechanisms.
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- Chemistry - A European Journal, 2023, v. 29, n. 56, p. 1, doi. 10.1002/chem.202301713
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- Article
Capturing a Pentacyclic Fragment‐Based Library Derived from Perophoramidine: Their Design, Synthesis and Evaluation as Anticancer Compounds by DNA Double‐Strand Breaks (DSB) and PARP‐1 Inhibition.
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- Chemistry - A European Journal, 2022, v. 28, n. 63, p. 1, doi. 10.1002/chem.202202405
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- Article
Isolation and Characterization of Monomeric Human RAD51: A Novel Tool for Investigating Homologous Recombination in Cancer.
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- Angewandte Chemie, 2023, v. 135, n. 51, p. 1, doi. 10.1002/ange.202312517
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- Article
Changes in double-strand DNA breaks predict delayed graft function (DGF) in Japanese renal allograft recipients.
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- Clinical & Experimental Nephrology, 2020, v. 24, n. 1, p. 96, doi. 10.1007/s10157-019-01793-8
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- Article
Image Analysis Using Imaris 10.1 Machine Learning to Quantitate γH2AX Foci in U87 Cells.
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- Microscopy & Microanalysis, 2024, v. 30, p. 1, doi. 10.1093/mam/ozae044.201
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- Article
Complete genome sequence of a novel sea otterpox virus.
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- Virus Genes, 2018, v. 54, n. 6, p. 756, doi. 10.1007/s11262-018-1594-8
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- Article
DNA Methylation and Establishing Memory.
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- Epigenetics Insights, 2022, v. 15, p. 1, doi. 10.1177/25168657211072499
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- Article
Defective homologous recombination and genomic instability predict increased responsiveness to carbon ion radiotherapy in pancreatic cancer.
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- NPJ Precision Oncology, 2025, v. 9, n. 1, p. 1, doi. 10.1038/s41698-025-00800-4
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- Article
Genomic hallmarks of endocrine therapy resistance in ER/PR+HER2- breast tumours.
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- Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-07606-x
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- Article
Toxoplasma gondii infection induces early host cell cycle arrest and DNA damage in primary human host cells by a MYR1-dependent mechanism.
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- Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-07374-0
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- Article
Characterization of macrophages associated with human skin models exposed to UV radiation.
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- Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-06975-z
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- Article
Double-strand break induced genome engineering in plants: Past, Present, Future.
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- 2017
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- Publication type:
- Abstract
Bi-allelic missense variants in MEI4 cause preimplantation embryonic arrest and female infertility.
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- Human Genetics, 2024, v. 143, n. 9/10, p. 1049, doi. 10.1007/s00439-023-02633-2
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- Article
Inactivating TDP2 missense mutation in siblings with congenital abnormalities reminiscent of fanconi anemia.
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- Human Genetics, 2023, v. 142, n. 9, p. 1417, doi. 10.1007/s00439-023-02589-3
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- Publication type:
- Article
Loss of SUN1 function in spermatocytes disrupts the attachment of telomeres to the nuclear envelope and contributes to non-obstructive azoospermia in humans.
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- Human Genetics, 2023, v. 142, n. 4, p. 531, doi. 10.1007/s00439-022-02515-z
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- Publication type:
- Article
Homozygous missense mutation in CCDC155 disrupts the transmembrane distribution of CCDC155 and SUN1, resulting in non-obstructive azoospermia and premature ovarian insufficiency in humans.
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- Human Genetics, 2022, v. 141, n. 11, p. 1795, doi. 10.1007/s00439-022-02459-4
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- Article
Biallelic variants in YRDC cause a developmental disorder with progeroid features.
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- Human Genetics, 2021, v. 140, n. 12, p. 1679, doi. 10.1007/s00439-021-02347-3
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- Article
A Hybrid Differential Equations Model for the Dynamics of Single and Double Strand Breaks of Cancer Cells Treated by Radiotherapy: A Definition for Tumor Life-Span.
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- Letters in Biomathematics, 2022, v. 9, n. 1, p. 141
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- Publication type:
- Article
Retrospective study of transcriptomic profiling identifies Thai triple-negative breast cancer patients who may benefit from immune checkpoint and PARP inhibitors.
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- PeerJ, 2023, p. 1, doi. 10.7717/peerj.15350
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- Article
In silico analysis on the functional and structural impact of Rad50 mutations involved in DNA strand break repair.
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- PeerJ, 2020, p. 1, doi. 10.7717/peerj.9197
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- Article
First record of ranavirus (Ranavirus sp.) in Siberia, Russia.
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- Herpetozoa, 2022, v. 35, p. 33, doi. 10.3897/herpetozoa.35.e79490
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- Article
Sensitive Detection of Hg<sup>2+</sup> with Switchable Electrochemiluminescence Luminophore and Disposable Bipolar Electrode.
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- ChemElectroChem, 2017, v. 4, n. 7, p. 1681, doi. 10.1002/celc.201600912
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- Publication type:
- Article
The BRCA1/BARD1 complex recognizes pre-ribosomal RNA to facilitate homologous recombination.
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- Cell Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41421-023-00590-8
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- Article
High-efficiency targeted transgene integration via primed micro-homologues.
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- Cell Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41421-023-00552-0
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- Publication type:
- Article
Deep sampling of gRNA in the human genome and deep-learning-informed prediction of gRNA activities.
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- Cell Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41421-023-00549-9
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- Article
Structures of Mec1/ATR kinase endogenously stimulated by different genotoxins.
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- Cell Discovery, 2022, v. 8, n. 1, p. 1, doi. 10.1038/s41421-022-00461-8
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- Article
Elimination of Cas9-dependent off-targeting of adenine base editor by using TALE to separately guide deaminase to target sites.
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- 2022
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- Publication type:
- Letter
A novel pathogenic variant in TDP2 causes spinocerebellar ataxia autosomal recessive 23 accompanied by pituitary tumor and hyperhidrosis: a case report.
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- Neurological Sciences, 2024, v. 45, n. 6, p. 2881, doi. 10.1007/s10072-024-07397-9
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- Article
Critical points in Comet assay silver staining procedure.
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- Macedonian Pharmaceutical Bulletin / Makedonsko Farmacevtski Bilten, 2020, v. 66, p. 29, doi. 10.33320/maced.pharm.bull.2020.66.03.014
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- Article
PTH 缺失通过诱导肾脏细胞衰老和衰老相关分泌表型分子表达 而加速肾脏纤维化.
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- Progress in Modern Biomedicine, 2024, v. 24, n. 16, p. 3006, doi. 10.13241/j.cnki.pmb.2024.16.002
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- Article
上调 miR-216a-5p 通过靶向双特异性磷酸酶 10 抑制胃癌细胞自噬 并增强放射敏感性.
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- Progress in Modern Biomedicine, 2022, v. 22, n. 22, p. 4206, doi. 10.13241/j.cnki.pmb.2022.22.002
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- Article
A Novel Combination of Ruthenium Polypyridyl Complex, [Ru(dppz)2PiP]<sup>2+</sup> and PARP Inhibitor, NU1025 for Cancer Treatment.
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- Malaysian Journal of Medicine & Health Sciences, 2019, v. 15, p. 26
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- Publication type:
- Article
Potential role of STAG1 mutations in genetic predisposition to childhood hematological malignancies.
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- Blood Cancer Journal, 2022, v. 12, n. 6, p. 1, doi. 10.1038/s41408-022-00683-9
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- Publication type:
- Article
Subclonal heterogeneity sheds light on the transformation trajectory in IGLV3-21<sup>R110</sup> chronic lymphocytic leukemia.
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- 2022
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- Publication type:
- Letter
The role of Box A of HMGB1 in producing γH2AX associated DNA breaks in lung cancer.
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- Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-87773-3
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- Publication type:
- Article
Repeated ionizing radiation exposure induces TRIP13 expression, conferring radioresistance in lung cancer cells.
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- Scientific Reports, 2025, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-84592-w
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- Publication type:
- Article
Heterozygous mutation in BRCA2 induces accelerated age-dependent decline in sperm quality with male subfertility in rats.
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- Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-024-84184-8
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- Publication type:
- Article
CHAMP1 premature termination codon mutations found in individuals with intellectual disability cause a homologous recombination defect through haploinsufficiency.
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- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-83435-y
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- Article
The effects of cell displacement on DNA damages in targeted radiation therapy using Geant4-DNA.
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- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-81863-4
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- Article
Agrobacterium virulence factors induce the expression of host DNA repair-related genes without promoting major genomic damage.
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- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-75525-8
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- Publication type:
- Article
Negative feedback loop in the activation of non-homologous end joining DNA repair pathway in Helicobacter pylori infected patients with gastritis.
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- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-74138-5
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- Publication type:
- Article
Involvement of the splicing factor SART1 in the BRCA1-dependent homologous recombination repair of DNA double-strand breaks.
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- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-68926-2
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- Publication type:
- Article