Works about DNA topoisomerases

Results: 497

Substituted Triazole-3,5-Diamine Compounds as Novel Human Topoisomerase III Beta Inhibitors.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6193, doi. 10.3390/ijms26136193

By:

Mamun, Yasir;
Chadni, Somaia Haque;
Rayala, Ramanjaneyulu;
Shafi, Hasham;
Ferdous, Shomita;
Pokhrel, Rudramani;
Nefzi, Adel;
Chapagain, Prem;
Tse-Dinh, Yuk-Ching

Publication type:

Article

Advancing Topoisomerase Research Using DNA Nanotechnology (Small Methods 6/2025).

Published in:

Small Methods, 2025, v. 9, n. 6, p. 1, doi. 10.1002/smtd.202570040

By:

Yesodi, Doron;
Katz, Adi;
Weizmann, Yossi

Publication type:

Article

Higher topoisomerase 2 alpha gene transcript levels predict better prognosis in GBM patients receiving temozolomide chemotherapy: identification of temozolomide as a TOP2A inhibitor.

Published in:

Journal of Neuro-Oncology, 2012, v. 107, n. 2, p. 289, doi. 10.1007/s11060-011-0758-3

By:

Arivazhagan, A.;
Kumar, Durairaj;
Sagar, Vinay;
Patric, Irene;
Sridevi, S.;
Thota, Balaram;
Srividya, Mallavarapu;
Prasanna, K.;
Thennarasu, K.;
Mondal, Neelima;
Hegde, A.;
Chandramouli, B.;
Santosh, V.;
Rao, M.;
Kondaiah, P.;
Somasundaram, K.

Publication type:

Article

Ribosomal DNA and the nucleolus in the context of genome organization.

Published in:

Chromosome Research, 2019, v. 27, n. 1/2, p. 109, doi. 10.1007/s10577-018-9600-5

By:

Potapova, Tamara A.;
Gerton, Jennifer L.

Publication type:

Article

Human genome-derived TOP1 matrix attachment region enhances transgene expression in the transfected CHO cells.

Published in:

Biotechnology Letters, 2019, v. 41, n. 6/7, p. 701, doi. 10.1007/s10529-019-02673-7

By:

Jia, Yan-Long;
Guo, Xiao;
Wang, Xi-Cheng;
Wang, Tian-Yun

Publication type:

Article

Molecular Docking and QSAR Study of 5-O-acylpinostrobin Derivatives as Topoisomerase IIa Inhibitors.

Published in:

Pharmacy & Pharmaceutical Sciences Journal / Jurnal Farmasi Dan Ilmu Kefarmasian Indonesia, 2024, v. 11, n. 1, p. 120, doi. 10.20473/jfiki.v11i12024.120-127

By:

Rahmah, Siti;
Widiandani, Tri;
Ekowati, Juni;
Priatna, Puja Adi

Publication type:

Article

An eukaryotic-type DNA topoisomerase is present in Halobacterium halobium.

Published in:

1996

By:

Becerra, A.;
Lazcano, A.

Publication type:

Abstract

Speculations on the origin of life and thermophily: Review of available information on reverse gyrase suggests that hyperthermophilic procaryotes are not so primitive.

Published in:

Origins of Life & Evolution of the Biosphere, 1995, v. 25, n. 1-3, p. 235, doi. 10.1007/BF01581587

By:

Forterre, Patrick;
Confalonier, Fabrice;
Charbonnier, Franck;
Duguet, Michel

Publication type:

Article

Genome mining reveals uncommon alkylpyrones as type III PKS products from myxobacteria.

Published in:

Journal of Industrial Microbiology & Biotechnology, 2019, v. 46, n. 3/4, p. 319, doi. 10.1007/s10295-018-2105-6

By:

Hug, Joachim J.;
Panter, Fabian;
Krug, Daniel;
Müller, Rolf

Publication type:

Article

Dermal mast cell density in fingers reflects severity of skin sclerosis in systemic sclerosis.

Published in:

Modern Rheumatology, 2013, v. 23, n. 6, p. 1151, doi. 10.3109/s10165-012-0813-8

By:

Yukawa, Sonosuke;
Yamaoka, Kunihiro;
Sawamukai, Norifumi;
Shimajiri, Shohei;
Kubo, Satoshi;
Miyagawa, Ippei;
Sonomoto, Koshiro;
Saito, Kazuyoshi;
Tanaka, Yoshiya

Publication type:

Article

De novo genome assembly of Camptotheca acuminata, a natural source of the anti-cancer compound camptothecin.

Published in:

GigaScience, 2017, v. 6, n. 9, p. 1, doi. 10.1093/gigascience/gix065

By:

Dongyan Zhao;
Hamilton, John P.;
Pham, Gina M.;
Crisovan, Emily;
Wiegert-Rininger, Krystle;
Vaillancourt, Brieanne;
Dean DellaPenna;
Buell, C. Robin

Publication type:

Article

Human DNA topoisomerase-IIα expression as a prognostic factor for transitional cell carcinoma of the urinary bladder.

Published in:

BJU International, 2003, v. 91, n. 6, p. 489, doi. 10.1046/j.1464-410X.2003.04118.x

By:

Koren, R.;
Kugel, V.;
Dekel, Y.;
Weissman, Y.;
Livne, P.M.;
Gal, R.

Publication type:

Article

DNA topoisomerases as targets for anticancer drugs.

Published in:

Journal of Clinical Pharmacy & Therapeutics, 2001, v. 26, n. 6, p. 405, doi. 10.1046/j.1365-2710.2001.00368.x

By:

Z.;
Topcu, Z.

Publication type:

Article

The RTR complex as caretaker of genome stability and its unique meiotic function in plants.

Published in:

Frontiers in Plant Science, 2014, v. 5, p. 1, doi. 10.3389/fpls.2014.00033

By:

Knoll, Alexander;
Schröpfer, Susan;
Puchta, Holger

Publication type:

Article

Synthesis and Anticancer Activity Evaluation of Novel Phenanthridine Derivatives.

Published in:

Frontiers in Oncology, 2019, p. N.PAG, doi. 10.3389/fonc.2019.00274

By:

Wan, Minghui;
Zhang, Lei;
Chen, Yiming;
Li, Qiang;
Fan, Wenli;
Xue, Qingxia;
Yan, Fang;
Song, Weiguo

Publication type:

Article

Camptothecin and podophyllotoxin derivatives: inhibitors of topoisomerase I and II - mechanisms of action, pharmacokinetics and toxicity profile.

Published in:

2006

By:

Hartmann, Jürg T;
Lipp, Hans-Peter;
Hartmann, Jörg T

Publication type:

journal article

Development and validation of stability indicating RP-HPLC method for estimation of Garenoxacin Mesylate in tablet dosage form.

Published in:

International Journal of Pharmacy & Life Sciences, 2017, v. 8, n. 3, p. 5504

By:

Panchal, Ashwinkumar B.;
Patel, Bhumi R.;
Patel, Jaymin G.;
Patel, Yogesh K.;
Maurya, Udayshankar J.

Publication type:

Article

RNA-Seq analysis discloses early senescence and nucleolar dysfunction triggered by Tdp1α depletion in Medicago truncatula.

Published in:

Journal of Experimental Botany, 2013, v. 64, n. 7, p. 1941, doi. 10.1093/jxb/ert063

By:

Donà, Mattia;
Confalonieri, Massimo;
Minio, Andrea;
Biggiogera, Marco;
Buttafava, Armando;
Raimondi, Elena;
Delledonne, Massimo;
Ventura, Lorenzo;
Sabatini, Maria Elisa;
Macovei, Anca;
Giraffa, Giorgio;
Carbonera, Daniela;
Balestrazzi, Alma

Publication type:

Article

Cell and Molecular Biology, Biochemistry and Molecular Physiology. Carrot cells contain two top1 genes having the coding capacity for two distinct DNA topoisomerases I.

Published in:

Journal of Experimental Botany, 2000, v. 51, n. 353, p. 1979, doi. 10.1093/jexbot/51.353.1979

By:

Balestrazzi, A.;
Chini, A.;
Bernacchia, G.;
Bracci, A.;
Luccarini, G.;
Cella, R.;
Carbonera, D.

Publication type:

Article

Identification of a Functional Type IA Topoisomerase, Ld TopIIIβ, from Kinetoplastid Parasite Leishmania donovani.

Published in:

Enzyme Research, 2011, p. 1, doi. 10.4061/2011/230542

By:

Banerjee, Bijoylaxmi;
Sen, Nilkantha;
Majumder, Hemanta K.

Publication type:

Article

"A-Review of Thiazolidinones: Versatile Heterocycles with Promising Therapeutic Potential".

Published in:

Oriental Journal of Chemistry, 2025, v. 41, n. 1, p. 30, doi. 10.13005/ojc/410104

By:

CHILAMAKURU, NARESH BABU;
NEELIMA, SATRASALA;
SUPRIYA, G.;
SARVESHA, E.;
DEVI, S. RAMA;
MAHESWARI, M. UMA;
MUKESH, S.;
TRIVENI, SINGIRISETTY

Publication type:

Article

Chromosome-nuclear envelope attachments affect interphase chromosome territories and entanglement.

Published in:

Epigenetics & Chromatin, 2018, v. 10, p. 1, doi. 10.1186/s13072-018-0173-5

By:

Kinney, Nicholas Allen;
Sharakhov, Igor V.;
Onufriev, Alexey V.

Publication type:

Article

Multiple roles of Spo11 in meiotic chromosome behavior.

Published in:

EMBO Journal, 2000, v. 19, n. 11, p. 2739, doi. 10.1093/emboj/19.11.2739

By:

Celerin, Martina;
Merino, Sandra T.;
Stone, Jana E.;
Menzie, Ann M.;
Zolan, Miriam E.

Publication type:

Article

Core histone N-termini play an essential role in mitotic chromosome condensation.

Published in:

EMBO Journal, 2000, v. 19, n. 3, p. 379, doi. 10.1093/emboj/19.3.379

By:

de la Barre, Anne-Elisabeth;
Gerson, Ceronique;
Gout, Stéphanie;
Creaven, Martina;
Allis, C. Dave;
Dimitrov, Stefan

Publication type:

Article

The essential role of yeast topoisomerase III in meiosis depends on recombination.

Published in:

EMBO Journal, 1999, v. 18, n. 6, p. 1701, doi. 10.1093/emboj/18.6.1701

By:

Gangloff, Serge;
de Massy, Bernard;
Arthur, Lane;
Rothstein, Rodney;
Fabre, Francis

Publication type:

Article

Replication-mediated DNA damage by camptothecin induces phosphorylation of RPA by DNA-dependent protein kinase and dissociates RPA:DNA-PK complexes.

Published in:

EMBO Journal, 1999, v. 18, n. 5, p. 1397, doi. 10.1093/emboj/18.5.1397

By:

Shao, Rong-Guang;
Cao, Chun-Xia;
Zhang, Hongliang;
Kohn, Kurt W.;
Wold, Marc S.;
Pommier, Yves

Publication type:

Article

Yeast telomeric sequences function as chromosomal anchorage points in vivo.

Published in:

EMBO Journal, 1997, v. 16, n. 3, p. 523, doi. 10.1093/emboj/16.3.523

By:

Mirabella, Allyson;
Gartenberg, Marc R.

Publication type:

Article

Plasmid-mediated quinolone resistance.

Published in:

Expert Review of Anti-infective Therapy, 2008, v. 6, n. 5, p. 685

By:

Martínez-Martínez, Luis;
María Eliecer Cano;
Rodríguez-Martínez, José Manuel;
Calvo, Jorge;
Pascual, Álvaro

Publication type:

Article

Leptosins isolated from marine fungus Leptoshaeria species inhibit DNA topoisomerases I and/or II and induce apoptosis by inactivation of Akt/protein kinase B.

Published in:

Cancer Science, 2005, v. 96, n. 11, p. 816, doi. 10.1111/j.1349-7006.2005.00117.x

By:

Yanagihara, Miyako;
Sasaki-Takahashi, Noriko;
Sugahara, Tetsuo;
Yamamoto, Seiko;
Shinomi, Masahito;
Yamashita, Izumi;
Hayashida, Masashi;
Yamanoha, Banri;
Numata, Atsushi;
Yamori, Takao;
Andoh, Toshiwo

Publication type:

Article

Topoisomerases I and III inhibit R-loop formation to prevent unregulated replication in the chromosomal Ter region of Escherichia coli.

Published in:

PLoS Genetics, 2018, v. 14, n. 9, p. 1, doi. 10.1371/journal.pgen.1007668

By:

Brochu, Julien;
Vlachos-Breton, Émilie;
Sutherland, Sarah;
Martel, Makisha;
Drolet, Marc

Publication type:

Article

The topoisomerase 3α zinc-finger domain T1 of Arabidopsis thaliana is required for targeting the enzyme activity to Holliday junction-like DNA repair intermediates.

Published in:

PLoS Genetics, 2018, v. 14, n. 9, p. 1, doi. 10.1371/journal.pgen.1007674

By:

Dorn, Annika;
Röhrig, Sarah;
Papp, Kristin;
Schröpfer, Susan;
Hartung, Frank;
Knoll, Alexander;
Puchta, Holger

Publication type:

Article

Enhanced osmotic stress tolerance in Medicago truncatula plants overexpressing the DNA repair gene MtTdp2α (tyrosyl-DNA phosphodiesterase 2).

Published in:

Plant Cell, Tissue & Organ Culture, 2014, v. 116, n. 2, p. 187, doi. 10.1007/s11240-013-0395-y

By:

Confalonieri, Massimo;
Faè, Matteo;
Balestrazzi, Alma;
Donà, Mattia;
Macovei, Anca;
Valassi, Alberto;
Giraffa, Giorgio;
Carbonera, Daniela

Publication type:

Article

Determination of in vitro absorption in Caco-2 monolayers of anticancer Ru(II)-based complexes acting as dual human topoisomerase and PARP inhibitors.

Published in:

BioMetals, 2019, v. 32, n. 1, p. 89, doi. 10.1007/s10534-018-0160-0

By:

de Camargo, Mariana S.;
De Grandis, Rone A.;
da Silva, Monize M.;
da Silva, Patricia B.;
Santoni, Mariana M.;
Eismann, Carlos E.;
Menegário, Amauri A.;
Cominetti, Marcia R.;
Zanelli, Cleslei F.;
Pavan, Fernando R.;
Batista, Alzir A.

Publication type:

Article

Human topoisomerase inhibition and DNA/BSA binding of Ru(II)- SCAR complexes as potential anticancer candidates for oral application.

Published in:

BioMetals, 2017, v. 30, n. 3, p. 321, doi. 10.1007/s10534-017-0008-z

By:

De Grandis, Rone;
Camargo, Mariana;
Silva, Monize;
Lopes, Érica;
Padilha, Elias;
Resende, Flávia;
Peccinini, Rosângela;
Pavan, Fernando;
Desideri, Alessandro;
Batista, Alzir;
Varanda, Eliana

Publication type:

Article

Escherichia coli topoisomerase I is an iron and zinc binding protein.

Published in:

BioMetals, 2011, v. 24, n. 4, p. 729, doi. 10.1007/s10534-011-9425-6

By:

Jianxin Lu;
Wu Wang;
Guoqiang Tan;
Landry, Aaron P.;
Peng Yi;
Fan Si;
Yaguang Ren;
Huangen Ding

Publication type:

Article

Extended Spectrum of Quinolone Resistance, Even to a Potential Latter Third-Generation Agent, as a Result of a Minimum of Two GrlA and Two GyrA Alterations in Quinolone-Resistant Staphylococcus aureus.

Published in:

Chemotherapy (0009-3157), 2010, v. 56, n. 2, p. 153, doi. 10.1159/000313529

By:

Eun-Jeong Yoon;
Chun-Yeong Lee;
Mi-Ja Shim;
Yu-Hong Min;
Ae-Ran Kwon;
Jongseo Lee;
Eung-Chil Choi

Publication type:

Article

2,3-Dehydrosilybin Is a Better DNA Topoisomerase I Inhibitor than Its Parental Silybin.

Published in:

Chemotherapy (0009-3157), 2009, v. 55, n. 1, p. 42, doi. 10.1159/000175466

By:

Thongphasuk, Piyanut;
Stremmel, Wolfgang;
Chamulitrat, Walee

Publication type:

Article

Topoisomerase I Inactivation by Reticulol and Its in vivo Cytotoxicity against B16F10 Melanoma.

Published in:

Chemotherapy (0009-3157), 2003, v. 49, n. 5, p. 257, doi. 10.1159/000072451

By:

D.S. Lim;
Y.S. Kwak;
K.H. Lee;
S.H. Ko;
W.H. Yoon;
W.Y. Lee;
C.H. Kim

Publication type:

Article

Structural basis for gate-DNA recognition and bending by type IIA topoisomerases.

Published in:

Nature, 2007, v. 450, n. 7173, p. 1201, doi. 10.1038/nature06396

By:

Dong, Ken C.;
Berger, James M.

Publication type:

Article

Antitumour drugs impede DNA uncoiling by topoisomerase I.

Published in:

Nature, 2007, v. 448, n. 7150, p. 213, doi. 10.1038/nature05938

By:

Koster, Daniel A.;
Palle, Komaraiah;
Bot, Elisa S. M.;
Bjornsti, Mary-Ann;
Dekker, Nynke H.

Publication type:

Article

Mechanochemical analysis of DNA gyrase using rotor bead tracking.

Published in:

2006

By:

Gore, Jeff;
Bryant, Zev;
Stone, Michael D.;
Nöllmann, Marcelo;
Cozzarelli, Nicholas R.;
Bustamante, Carlos

Publication type:

Letter

Minor groove dimeric bisbenzimidazoles inhibit in vitro DNA binding to eukaryotic DNA topoisomerase I.

Published in:

Biochemistry (00062979), 2010, v. 75, n. 6, p. 695, doi. 10.1134/S0006297910060039

By:

Susova, O. Yu.;
Ivanov, A. A.;
Ruiz, S. S. Morales;
Lesovaya, E. A.;
Gromyko, A. V.;
Streltsov, S. A.;
Zhuze, A. L.

Publication type:

Article

Structure and mechanism of action of type IA DNA topoisomerases.

Published in:

Biochemistry (00062979), 2009, v. 74, n. 13, p. 1467, doi. 10.1134/S0006297909130045

By:

Bugreev, D. V.;
Nevinsky, G. A.

Publication type:

Article

Role of Supercoiling and Topoisomerases in DNA Knotting.

Published in:

DNA (2673-8856), 2024, v. 4, n. 2, p. 170, doi. 10.3390/dna4020010

By:

Cebrián, Jorge;
Martínez-Robles, María-Luisa;
Martínez, Victor;
Hernández, Pablo;
Krimer, Dora B.;
Schvartzman, Jorge B.;
Fernández-Nestosa, María-José

Publication type:

Article

DNA supercoiling and transcription in bacteria: a two-way street.

Published in:

BMC Molecular & Cell Biology, 2019, p. 1, doi. 10.1186/s12860-019-0211-6

By:

Dorman, Charles J.

Publication type:

Article

DNA TOPOISOMERASES: A REVIEW ON THEIR FUNCTIONAL ASPECTS IN CELL DIVISION.

Published in:

Era's Journal of Medical Research, 2018, v. 5, n. 2, p. 162, doi. 10.24041/ejmr2018.85

By:

Srivastava, Aditi;
Ahmad, Rumana;
Srivastava, A. N.

Publication type:

Article

DNA Topology and Topoisomerases.

Published in:

Biochemistry & Molecular Biology Education, 2009, v. 37, n. 1, p. 2, doi. 10.1002/bmb.20244

By:

Deweese, Joseph E.;
Osheroff, Michael A.;
Osheroff, Neil

Publication type:

Article

Quantification of DNA by Agarose Gel Electrophoresis and Analysis of the Topoisomers of Plasmid and M13 DNA Following Treatment with a Restriction Endonuclease or DNA Topoisomerase I.

Published in:

Biochemistry & Molecular Biology Education, 2005, v. 33, n. 1, p. 28, doi. 10.1002/bmb.2005.494033010410

By:

Tweedie, John W.;
Stowell, Kathryn M.

Publication type:

Article

DNA topoisomerase 2 mutant allele mildly delays the mitotic progression and activates the checkpoint protein kinase Chk1 in fission yeast Schizosaccharomyces pombe.

Published in:

Genetics Research, 2011, v. 93, n. 4, p. 275, doi. 10.1017/S0016672311000188

By:

YADAV, SUDHANSHU;
VERMA, SUMIT KUMAR;
AHMED, SHAKIL

Publication type:

Article

Alleviatory efficacy of achillea millefolium L. in etoxazole-mediated toxicity in allium cepa L.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-81586-6

By:

Topatan, Zeynep Şule;
Kalefetoğlu Macar, Tuğçe;
Macar, Oksal;
Yalçin, Emine;
Çavuşoğlu, Kültiğin;
Acar, Ali;
Kutluer, Fatih

Publication type:

Article