Works matching DE "DNA topoisomerase II"

Results: 1505

Hypercellular Proinflammatory Microenvironment Inhibits the Etoposide-Induced DNA Damage in Acute Monocytic Leukemia Cells.

Published in:

Biochemistry (00062979), 2025, v. 90, n. 5, p. 553, doi. 10.1134/S000629792560019X

By:

Kobyakova, Margarita I.;
Krasnov, Kirill S.;
Krestinina, Olga V.;
Baburina, Yulia L.;
Senotov, Anatoly S.;
Lomovskaya, Yana V.;
Meshcheriakova, Elena I.;
Lomovsky, Alexey I.;
Zvyagina, Alena I.;
Pyatina, Kira V.;
Fadeeva, Irina S.;
Fadeev, Roman S.

Publication type:

Article

COMPUTATIONAL BINDING STUDIES AND BIOACTIVITY EVALUATION FOR CERTAIN SCHIFF BASE METAL-COMPLEXES TRANSFORMED FROM CIPROFLOXACIN.

Published in:

Chemical Problems / Kimya Problemləri, 2025, v. 23, n. 3, p. 449, doi. 10.32737/2221-8688-2025-3-449-461

By:

Al-Obedi, Ahmad D.;
Al-Nama, Khansaa Sh.

Publication type:

Article

Eco-friendly TiO2–ZnO nano-catalysts: synthesis, catalytic performance in synthesis of α-amino/hydroxyphosphonates and their ADME, docking and antimicrobial studies.

Published in:

Research on Chemical Intermediates, 2025, v. 51, n. 7, p. 3767, doi. 10.1007/s11164-025-05622-4

By:

Ummadi, Ravindra Reddy;
Ratnakaram, Venkata Nadh;
Devineni, Subba Rao;
Subramanyam, Chennamsetty;
Pavuluri, Chandra Mouli

Publication type:

Article

Chemical Composition and Biological Activity of Vietnamese Vernonia amygdalina Essential Oil: In Vitro and In Silico Studies.

Published in:

Tropical Journal of Natural Product Research, 2025, v. 9, n. 5, p. 2263, doi. 10.26538/tjnpr/v9i5.54

By:

Ngu, Truong N.;
Dam, Thi B. H.;
Nguyen, Duy T.;
Do, Van H.;
Bui, Lan A.;
Truong, Hieu P. C.;
Tran, Manh H.;
Nguyen, Phi H.;
Huong, Nguyen T. M.;
To, Dao C.

Publication type:

Article

Structural insight in understanding the impact of mutation at position 88 and 94 of DNA gyrase A of Mycobacterium tuberculosis in developing resistance against delafloxacin.

Published in:

Journal of Biological Physics, 2025, v. 51, n. 1, p. 1, doi. 10.1007/s10867-025-09686-6

By:

Rai, Sumit Kumar;
Singh, Dev Bukhsh;
Singh, Satendra

Publication type:

Article

Review of Recent Advances in Thiazolidin-4-One Derivatives as Promising Antitubercular Agents (2021–Present).

Published in:

Molecules, 2025, v. 30, n. 10, p. 2201, doi. 10.3390/molecules30102201

By:

Drzał, Wiktoria;
Trotsko, Nazar

Publication type:

Article

Synthesis of Novel Thiazole/Thiadiazole Conjugates of Fluoroquinolones as Potent Antibacterial and Antimycobacterial Agents.

Published in:

Chemical Biology & Drug Design, 2025, v. 105, n. 5, p. 1, doi. 10.1111/cbdd.70126

By:

Poyraz Yılmaz, Pınar;
Kulabaş, Necla;
Bozdeveci, Arif;
Vagolu, Siva Krishna;
Imran, Mohd;
Tatar, Esra;
Alpay Karaoğlu, Şengül;
Sriram, Dharmarajan;
Mahmood, Ammar A. Razzak;
Küçükgüzel, İlkay

Publication type:

Article

Exploring Thiazole‐Based Heterocycles: Synthesis, Bioactivity, and Molecular Docking for Antimicrobial Applications.

Published in:

Chemical Biology & Drug Design, 2025, v. 105, n. 5, p. 1, doi. 10.1111/cbdd.70124

By:

Abumelha, Hana M.;
Sefrji, Fatmah O.;
Alrefaei, Abdulmajeed F.;
Mojally, Mariam;
Alotaibi, Fatimah A.;
Alomari, Khadra B.;
Madkhaly, Fatimah M.;
El‐Metwaly, Nashwa M.

Publication type:

Article

PKG‐Mediated Phosphorylation of TOP2A Activates HDAC to Drive Photoreceptor Cell Death in rd1 Mouse Inherited Retinal Degeneration.

Published in:

Journal of Neurochemistry, 2025, v. 169, n. 5, p. 1, doi. 10.1111/jnc.70077

By:

Dong, Yujie;
Zuo, Wandong;
Li, Yan;
Feng, Xiaoxiao;
Guo, Chunming;
Chen, Maorong;
Yan, Jie;
Hou, Chunjiang;
Peng, Hua;
Hu, Zhulin;
Liu, Hai;
Paquet‐Durand, François;
Jiao, Kangwei

Publication type:

Article

Antimicrobial activity, synthesis, and docking study of some novel arylazo-1,3-thiazolopyrimidine and arylazo-1,3-thiazolopyridopyrimidine derivatives.

Published in:

BMC Chemistry, 2025, v. 19, n. 1, p. 1, doi. 10.1186/s13065-025-01506-1

By:

Qurban, Jihan;
Alqarni, Sara A.;
Alalawy, Adel I.;
Alshammari, Nawaa Ali H.;
Ashour, Gadeer R. S.;
Alnoman, Maryam M.;
Katuah, Hanadi A.;
El-Metwaly, Nashwa M.

Publication type:

Article

Virtual Screening and Molecular Dynamics Simulation Targeting the ATP Domain of African Swine Fever Virus Type II DNA Topoisomerase.

Published in:

Viruses (1999-4915), 2025, v. 17, n. 5, p. 681, doi. 10.3390/v17050681

By:

Zhao, Rui;
Hou, Lezi;
Tesfagaber, Weldu;
Song, Linfei;
Zhang, Zhenjiang;
Li, Fang;
Bu, Zhigao;
Zhao, Dongming

Publication type:

Article

Positive cardioprotective effects of Topoisomerase II poison, LS1, in doxorubicin treatment.

Published in:

Bios (0005-3155), 2025, v. 96, n. 2, p. 59, doi. 10.1893/BIOS-D-24-00009

By:

Keenehan, Katelin;
Millen, Jonathan I.

Publication type:

Article

Newborn apical resection preserves the proliferative capacity of cardiomyocytes located throughout the left ventricle.

Published in:

Stem Cells, 2025, v. 43, n. 5, p. 1, doi. 10.1093/stmcls/sxaf018

By:

Hao, Kaili;
Nguyen, Thanh;
Nakada, Yuji;
Walcott, Gregory;
Wei, Yuhua;
Wu, Yalin;
Garry, Daniel J;
Yao, Peng;
Zhang, Jianyi

Publication type:

Article

Comprehensive In Vitro and In Silico Analysis of Antimicrobial and Insecticidal Properties of Essential Oil of Myrtus communis L. from Algeria.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4754, doi. 10.3390/ijms26104754

By:

Barboucha, Ghozlane;
Rahim, Noureddine;
Bramki, Amina;
Boulebd, Houssem;
Andolfi, Anna;
Boulacheb, Khaoula;
Boulacel, Amina;
Salvatore, Maria Michela;
Masi, Marco

Publication type:

Article

New Dimethoxyaryl-Sesquiterpene Derivatives with Cytotoxic Activity Against MCF-7 Breast Cancer Cells: From Synthesis to Topoisomerase I/II Inhibition and Cell Death Mechanism Studies.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4539, doi. 10.3390/ijms26104539

By:

Araque, Ileana;
Vergara, Rut;
Mella, Jaime;
Aránguiz, Pablo;
Espinoza-Catalán, Luis;
Salas, Cristian O.;
Barrero, Alejandro F.;
Quílez del Moral, José;
Villena, Joan;
Cuellar, Mauricio A.

Publication type:

Article

Transcription-generated torsional stress destabilizes nucleosomes.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 1, p. 88, doi. 10.1038/nsmb.2723

By:

Teves, Sheila S;
Henikoff, Steven

Publication type:

Article

Transcription-dependent dynamic supercoiling is a short-range genomic force.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 3, p. 396, doi. 10.1038/nsmb.2517

By:

Kouzine, Fedor;
Gupta, Ashutosh;
Baranello, Laura;
Wojtowicz, Damian;
Ben-Aissa, Khadija;
Liu, Juhong;
Przytycka, Teresa M;
Levens, David

Publication type:

Article

Mechanism of repair of 5?-topoisomerase II-DNA adducts by mammalian tyrosyl-DNA phosphodiesterase 2.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 12, p. 1363, doi. 10.1038/nsmb.2418

By:

Schellenberg, Matthew J;
Appel, C Denise;
Adhikari, Sanjay;
Robertson, Patrick D;
Ramsden, Dale A;
Williams, R Scott

Publication type:

Article

Tyrosyl DNA phosphodiesterase 2, an enzyme fit for purpose.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 12, p. 1212, doi. 10.1038/nsmb.2455

By:

Caldecott, Keith W.

Publication type:

Article

Structure of a topoisomerase II-DNA-nucleotide complex reveals a new control mechanism for ATPase activity.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 11, p. 1147, doi. 10.1038/nsmb.2388

By:

Schmidt, Bryan H;
Osheroff, Neil;
Berger, James M

Publication type:

Article

ATP binding controls distinct structural transitions of Escherichia coli DNA gyrase in complex with DNA.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 5, p. 538, doi. 10.1038/nsmb.2278

By:

Basu, Aakash;
Schoeffler, Allyn J;
Berger, James M;
Bryant, Zev

Publication type:

Article

Structural insight into the quinolone–DNA cleavage complex of type IIA topoisomerases.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 6, p. 667, doi. 10.1038/nsmb.1604

By:

Laponogov, Ivan;
Sohi, Maninder K;
Veselkov, Dennis A.;
Pan, Xiao-Su;
Sawhney, Ritica;
Thompson, Andrew W.;
McAuley, Katherine E.;
Fisher, L. Mark;
Sanderson, Mark R.

Publication type:

Article

Under DNA stress, gyrase makes the sign of the cross.

Published in:

Nature Structural & Molecular Biology, 2007, v. 14, n. 4, p. 256, doi. 10.1038/nsmb0407-256

By:

Higgins, N. Patrick

Publication type:

Article

Multiple modes of Escherichia coli DNA gyrase activity revealed by force and torque.

Published in:

Nature Structural & Molecular Biology, 2007, v. 14, n. 4, p. 264, doi. 10.1038/nsmb1213

By:

Nöllmann, Marcelo;
Stone, Michael D.;
Bryant, Zev;
Gore, Jeff;
Crisona, Nancy J.;
Hong, Seok-Cheol;
Mitelheiser, Sylvain;
Maxwell, Anthony;
Bustamante, Carlos;
Cozzarelli, Nicholas R.

Publication type:

Article

Molecular markers of prognosis in canine cortisol‐secreting adrenocortical tumours.

Published in:

Veterinary & Comparative Oncology, 2019, v. 17, n. 4, p. 545, doi. 10.1111/vco.12521

By:

Sanders, Karin;
Staalduinen, Gerjanne J.;
Uijens, Maarten C. M.;
Mol, Jan A.;
Teske, Erik;
Slob, Adri;
Hesselink, Jan Willem;
Kooistra, Hans S.;
Galac, Sara

Publication type:

Article

Topoisomerase II Hypersensitive Sites in the 5"-Terminal Region of Human Dystrophin Gene.

Published in:

Doklady Biochemistry & Biophysics, 2001, v. 378, n. 1-6, p. 198, doi. 10.1023/A:1011565229893

By:

Bystritskii, A. A.;
Hancock, R.;
Razin, S. V.;
Yarovaya, O. V.

Publication type:

Article

The Loop Pattern of Chromosomal DNA May Significantly Differ in AT-Rich and GC-Rich Isochores.

Published in:

Doklady Biochemistry & Biophysics, 2001, v. 377, n. 1-6, p. 135, doi. 10.1023/A:1011508613419

By:

Svetlova, E. Yu.;
Razin, S. V.

Publication type:

Article

Topologically‐Interlocked Minicircles as Probes of DNA Topology and DNA‐Protein Interactions.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 22, p. 1, doi. 10.1002/chem.202200108

By:

Rajendran, Arivazhagan;
Krishnamurthy, Kirankumar;
Park, Seojeong;
Nakata, Eiji;
Kwon, Youngjoo;
Morii, Takashi

Publication type:

Article

Nanoparticles for Triple Drug Release for Combined Chemo‐ and Photodynamic Therapy.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 59, p. 14610, doi. 10.1002/chem.202101842

By:

Martínez‐Edo, Gabriel;
Xue, Evelyn Y.;
Ha, Summer Y. Y.;
Pontón, Iris;
González‐Delgado, José Antonio;
Borrós, Salvador;
Torres, Tomás;
Ng, Dennis K. P.;
Sánchez‐García, David

Publication type:

Article

Acetylenic Replacement of Albicidin's Methacrylamide Residue Circumvents Detrimental E/Z Photoisomerization and Preserves Antibacterial Activity.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 35, p. 9077, doi. 10.1002/chem.202100523

By:

Behroz, Iraj;
Kleebauer, Leonardo;
Hommernick, Kay;
Seidel, Maria;
Grätz, Stefan;
Mainz, Andi;
Weston, John B.;
Süssmuth, Roderich D.

Publication type:

Article

Synthesis and Biological Activity of Ferrocenyl and Ruthenocenyl Analogues of Etoposide: Discovery of a Novel Dual Inhibitor of Topoisomerase II Activity and Tubulin Polymerization.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 20, p. 6254, doi. 10.1002/chem.202005133

By:

Chrabąszcz, Karolina;
Błauż, Andrzej;
Gruchała, Martyna;
Wachulec, Marcin;
Rychlik, Błażej;
Plażuk, Damian

Publication type:

Article

Dual‐Acting Small‐Molecule Inhibitors Targeting Mycobacterial DNA Replication.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 47, p. 10849, doi. 10.1002/chem.202001725

By:

Singh, Meenakshi;
Ilic, Stefan;
Tam, Benjamin;
Ben‐Ishay, Yesmin;
Sherf, Dror;
Pappo, Doron;
Akabayov, Barak

Publication type:

Article

Cover Feature: Cystobactamid 507: Concise Synthesis, Mode of Action, and Optimization toward More Potent Antibiotics (Chem. Eur. J. 32/2020).

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 32, p. 7141, doi. 10.1002/chem.202002127

By:

Elgaher, Walid A. M.;
Hamed, Mostafa M.;
Baumann, Sascha;
Herrmann, Jennifer;
Siebenbürger, Lorenz;
Krull, Jana;
Cirnski, Katarina;
Kirschning, Andreas;
Brönstrup, Mark;
Müller, Rolf;
Hartmann, Rolf W.

Publication type:

Article

Luminescent PtII and PtIV Platinacycles with Anticancer Activity Against Multiplatinum‐Resistant Metastatic CRC and CRPC Cell Models.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 9, p. 1947, doi. 10.1002/chem.201905325

By:

Lázaro, Ariadna;
Balcells, Cristina;
Quirante, Josefina;
Badia, Josefa;
Baldomà, Laura;
Ward, Jas S.;
Rissanen, Kari;
Font‐Bardia, Mercè;
Rodríguez, Laura;
Crespo, Margarita;
Cascante, Marta

Publication type:

Article

Extensive Structure–Activity Relationship Study of Albicidin's C‐Terminal Dipeptidic p‐Aminobenzoic Acid Moiety.

Published in:

Chemistry - A European Journal, 2019, v. 25, n. 72, p. 16538, doi. 10.1002/chem.201904752

By:

Behroz, Iraj;
Durkin, Patrick;
Grätz, Stefan;
Seidel, Maria;
Rostock, Lida;
Spinczyk, Marcello;
Weston, John B.;
Süssmuth, Roderich D.

Publication type:

Article

Isolation and evaluation of Bacillus subtilis RSS-1 as a potential biocontrol agent against Sclerotinia sclerotiorum on oilseed rape.

Published in:

European Journal of Plant Pathology, 2023, v. 166, n. 1, p. 9, doi. 10.1007/s10658-023-02642-x

By:

Cao, Shun;
Jiang, Bingxin;
Yang, Guogen;
Pan, Guangxue;
Pan, Yuemin;
Chen, Fangxin;
Gao, Zhimou;
Dai, Yuli

Publication type:

Article

TOP2B is required for compartment strength changes upon retinoic acid treatment in SH-SY5Y cells.

Published in:

Chromosome Research, 2025, v. 33, n. 1, p. 1, doi. 10.1007/s10577-025-09764-4

By:

Hildebrand, Erica M.;
Cowell, Ian G.;
Khazeem, Mushtaq M.;
Sambare, Snehal;
Uyan, Ozgun;
Dekker, Job;
Austin, Caroline A.

Publication type:

Article

Progression of chromosomal damage induced by etoposide in G2 phase in a DNA-PKcs-deficient context.

Published in:

Chromosome Research, 2015, v. 23, n. 4, p. 719, doi. 10.1007/s10577-015-9478-4

By:

Palmitelli, Micaela;
Campos-Nebel, Marcelo;
González-Cid, Marcela

Publication type:

Article

How to be a mitotic chromosome.

Published in:

Chromosome Research, 2011, v. 19, n. 3, p. 307, doi. 10.1007/s10577-011-9198-3

By:

Moser, Sandra;
Swedlow, Jason

Publication type:

Article

Expedition of sulfur‐containing heterocyclic derivatives as cytotoxic agents in medicinal chemistry: A decade update.

Published in:

Medicinal Research Reviews, 2022, v. 42, n. 1, p. 513, doi. 10.1002/med.21852

By:

Laxmikeshav, Kritika;
Kumari, Pooja;
Shankaraiah, Nagula

Publication type:

Article

Bee Trypanosomatids: First Steps in the Analysis of the Genetic Variation and Population Structure of Lotmaria passim, Crithidia bombi and Crithidia mellificae.

Published in:

Microbial Ecology, 2022, v. 84, n. 3, p. 856, doi. 10.1007/s00248-021-01882-w

By:

Bartolomé, Carolina;
Buendía-Abad, María;
Ornosa, Concepción;
De la Rúa, Pilar;
Martín-Hernández, Raquel;
Higes, Mariano;
Maside, Xulio

Publication type:

Article

Exploiting bacterial DNA gyrase as a drug target: current state and perspectives.

Published in:

Applied Microbiology & Biotechnology, 2011, v. 92, n. 3, p. 479, doi. 10.1007/s00253-011-3557-z

By:

Collin, Frédéric;
Karkare, Shantanu;
Maxwell, Anthony

Publication type:

Article

An insight into the evolution of introns in the <italic>gyrase A</italic> gene of plants.

Published in:

Plant Systematics & Evolution, 2018, v. 304, n. 4, p. 521, doi. 10.1007/s00606-018-1503-6

By:

Manna, Mrinalini;
Fartyal, Dhirendra;
Achary, V. Mohan M.;
Agarwal, Aakrati;
Reddy, Malireddy K.

Publication type:

Article

Synthesis and biological evaluation of novel naphthoquinone fused cyclic aminoalkylphosphonates and aminoalkylphosphonic monoester.

Published in:

Amino Acids, 2008, v. 35, n. 2, p. 463

By:

Z. W. Miao;
J. Wang;
R. Y. Chen;
X. D. Zhang

Publication type:

Article

Expression and biological significance of topoisomerase II α (TOP2A) in oral squamous cell carcinoma.

Published in:

Discover Oncology, 2024, v. 15, n. 1, p. 1, doi. 10.1007/s12672-024-01295-4

By:

Cheng, Xujie;
Wei, Yuxing;
Deng, Limei;
Dong, Hao;
Wei, Huiping;
Xie, Cheng;
Tuo, Yangjuan;
Chen, Meiyu;
Qin, Hao;
Cao, Yong

Publication type:

Article

Phytochemical, Antimicrobial, Antioxidant, and In Vitro Cytotoxicity Evaluation of Echinops erinaceus Kit Tan.

Published in:

Separations (2297-8739), 2022, v. 9, n. 12, p. 447, doi. 10.3390/separations9120447

By:

Sweilam, Sherouk Hussein;
Abdel Bar, Fatma M.;
Foudah, Ahmed I.;
Alqarni, Mohammed H.;
Elattal, Nouran A.;
El-Gindi, Omayma D.;
El-Sherei, Moshera M.;
Abdel-Sattar, Essam

Publication type:

Article

Acridine derivatives as inhibitors/poisons of topoisomerase II.

Published in:: Journal of Applied Toxicology, 2022, v. 42, n. 4, p. 544, doi. 10.1002/jat.4238
Publication type:: Article

A new look at 9‐substituted acridines with various biological activities.

Published in:

Journal of Applied Toxicology, 2021, v. 41, n. 1, p. 175, doi. 10.1002/jat.4072

By:

Kozurkova, Maria;
Sabolova, Danica;
Kristian, Pavol

Publication type:

Article

Comparison of Clinical Manifestations, Antimicrobial Susceptibility Patterns, and Mutations of Fluoroquinolone Target Genes between Elizabethkingia meningoseptica and Elizabethkingia anophelis Isolated in Taiwan.

Published in:

Journal of Clinical Medicine, 2018, v. 7, n. 12, p. 538, doi. 10.3390/jcm7120538

By:

Lin, Jiun-Nong;
Lai, Chung-Hsu;
Yang, Chih-Hui;
Huang, Yi-Han

Publication type:

Article

Antibacterial activity of active peptide from marine macroalgae Chondrus crispus protein hydrolysate against Staphylococcus aureus.

Published in:

Pharmacia (0428-0296), 2023, v. 70, n. 4, p. 983, doi. 10.3897/pharmacia.70.e112215

By:

Habibie, Ahmad;
Raharjo, Tri Joko;
Swasono, Respati Tri;
Retnaningrum, Endah

Publication type:

Article