Works about DNA topoisomerase I

Results: 1241

Substituted Triazole-3,5-Diamine Compounds as Novel Human Topoisomerase III Beta Inhibitors.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6193, doi. 10.3390/ijms26136193

By:

Mamun, Yasir;
Chadni, Somaia Haque;
Rayala, Ramanjaneyulu;
Shafi, Hasham;
Ferdous, Shomita;
Pokhrel, Rudramani;
Nefzi, Adel;
Chapagain, Prem;
Tse-Dinh, Yuk-Ching

Publication type:

Article

Targeting Topoisomerase I and DNA with LCS1269 Drives Glioblastoma Cell Death Despite ATM/Chk1/BRCA1/RAD51 Signaling Pathway Activation.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6014, doi. 10.3390/ijms26136014

By:

Kalitin, Nikolay;
Savchenko, Ekaterina;
Samoylenkova, Nadezhda;
Koroleva, Natalia;
Lushnikova, Anna;
Karamysheva, Aida;
Pavlova, Galina

Publication type:

Article

Mitotic genome folding.

Published in:

Journal of Cell Biology, 2025, v. 224, n. 7, p. 1, doi. 10.1083/jcb.202504075

By:

Tatsuya Hirano

Publication type:

Article

Efficacy and safety of Sacituzumab govitecan in solid tumors: a systematic review and meta-analysis.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1624386

By:

Zhang, Yaping;
Chen, Jian;
Wang, Xiaoyan;
Wang, Hui;
Chen, Xiaoli;
Hong, Jianfeng;
Fang, Hongming

Publication type:

Article

Total Synthesis and Biological Evaluation of 22-Hydroxyacuminatine and the Related Natural Products Norketoyobyrine and Naucleficine.

Published in:

Molecules, 2025, v. 30, n. 12, p. 2650, doi. 10.3390/molecules30122650

By:

Mizuno, Shohta;
Nishiyama, Takashi;
Bessho, Hana;
Nakamura, Tetsuya;
Oe, Tomoki;
Hayashi, Nanako;
Hieda, Yuhzo;
Motoyashiki, Toshio;
Hata, Toshiyuki;
Hatae, Noriyuki;
Choshi, Tominari

Publication type:

Article

Patterns and Mechanisms of Ancestral Histone Protein Inheritance in Budding Yeast.

Published in:

PLoS Biology, 2011, v. 9, n. 6, p. 1, doi. 10.1371/journal.pbio.1001075

By:

Radman-Livaja, Marta;
Verzijlbergen, Kitty F.;
Weiner, Assaf;
van Welsem, Tibor;
Friedman, Nir;
Rando, Oliver J.;
van Leeuwen, Fred

Publication type:

Article

Flavonolignan Conjugates as DNA-binding Ligands and Topoisomerase I Inhibitors: Electrochemical and Electrophoretic Approaches.

Published in:

Electroanalysis, 2016, v. 28, n. 11, p. 2866, doi. 10.1002/elan.201600146

By:

Zatloukalová, Martina;
Vavříková, Eva;
Pontinha, Ana Dora Rodrigues;
Coufal, Jan;
Křen, Vladimír;
Fojta, Miroslav;
Ulrichová, Jitka;
Oliveira‐Brett, Ana Maria;
Vacek, Jan

Publication type:

Article

Selective anti-tumor activity of the novel fluoropyrimidine polymer F10 towards G48a orthotopic GBM tumors.

Published in:

Journal of Neuro-Oncology, 2014, v. 116, n. 3, p. 447, doi. 10.1007/s11060-013-1321-1

By:

Gmeiner, William;
Lema-Tome, Carla;
Gibo, Denise;
Jennings-Gee, Jamie;
Milligan, Carol;
Debinski, Waldemar

Publication type:

Article

Vorinostat enhances the cytotoxic effects of the topoisomerase I inhibitor SN38 in glioblastoma cell lines.

Published in:

Journal of Neuro-Oncology, 2010, v. 99, n. 2, p. 201, doi. 10.1007/s11060-010-0127-7

By:

Sarcar, Bhaswati;
Kahali, Soumen;
Chinnaiyan, Prakash

Publication type:

Article

Non-PEGylated liposomes for convection-enhanced delivery of topotecan and gadodiamide in malignant glioma: initial experience.

Published in:

Journal of Neuro-Oncology, 2009, v. 95, n. 2, p. 185, doi. 10.1007/s11060-009-9917-1

By:

Grahn, Amy;
Bankiewicz, Krystof;
Dugich-Djordjevic, Millicent;
Bringas, John;
Hadaczek, Piotr;
Johnson, Greg;
Eastman, Simon;
Luz, Matthias

Publication type:

Article

Pegylated-liposomal doxorubicin and oral topotecan in eight children with relapsed high-grade malignant brain tumors.

Published in:

Journal of Neuro-Oncology, 2008, v. 86, n. 2, p. 175

By:

Gisela Janssen;
Anne-Kathrin Liebeskind;
Axel Sauerbrey;
Meinolf Suttorp;
Peter Hau

Publication type:

Article

Clinical trial of CPT-11 and VM-26/VP-16 for patients with recurrent malignant brain tumors.

Published in:

Journal of Neuro-Oncology, 2007, v. 82, n. 2, p. 177, doi. 10.1007/s11060-006-9261-7

By:

Lynn Feun;
Angela Marini;
Howard Landy;
Arnold Markoe;
Deborah Heros;
Carlos Robles;
Cristina Herrera;
Niramol Savaraj

Publication type:

Article

Chitosan Schiff base electrospun fabrication and molecular docking assessment for nonleaching antibacterial nanocomposite production.

Published in:

Cellulose, 2023, v. 30, n. 6, p. 3505, doi. 10.1007/s10570-023-05124-9

By:

Ali, Eman AboBakr;
Abo-Salem, Heba M.;
Arafa, Amany A.;
Nada, Ahmed A.

Publication type:

Article

Human genome-derived TOP1 matrix attachment region enhances transgene expression in the transfected CHO cells.

Published in:

Biotechnology Letters, 2019, v. 41, n. 6/7, p. 701, doi. 10.1007/s10529-019-02673-7

By:

Jia, Yan-Long;
Guo, Xiao;
Wang, Xi-Cheng;
Wang, Tian-Yun

Publication type:

Article

PiggyBac transposon-mediated mutagenesis and application in yeast Komagataella phaffii.

Published in:

Biotechnology Letters, 2018, v. 40, n. 9/10, p. 1365, doi. 10.1007/s10529-018-2592-6

By:

Zhu, Jinxiang;
Zhu, Qiaoyun;
Gong, Ruiqing;
Xu, Qin;
Cai, Menghao;
Jiang, Tianyi;
Zhou, Xiangshan;
Zhou, Mian;
Zhang, Yuanxing

Publication type:

Article

TOP2A deficiency leads to human recurrent spontaneous abortion and growth retardation of mouse pre-implantation embryos.

Published in:

Molecular Medicine, 2022, v. 28, n. 1, p. 1, doi. 10.1186/s10020-022-00592-4

By:

Duan, Yuhan;
Fu, Huijia;
Huang, Jiayu;
Yin, Nanlin;
Liu, Linhong;
Liu, Xiru

Publication type:

Article

Gender and ethnicity differences in the prevalence of scleroderma-related autoantibodies.

Published in:

Clinical Rheumatology, 2011, v. 30, n. 10, p. 1333, doi. 10.1007/s10067-011-1751-0

By:

Krzyszczak, Malgorzata;
Li, Yi;
Ross, Steven;
Ceribelli, Angela;
Chan, Edward;
Bubb, Michael;
Sobel, Eric;
Reeves, Westley;
Satoh, Minoru

Publication type:

Article

Anti-topoisomerase I antibodies in systemic lupus erythematosus as a marker of severe nephritis.

Published in:

2006

By:

Hamidou, Mohamed;
Audrain, Marie;
Masseau, Agathe;
Agard, Christian;
Moreau, Anne

Publication type:

Letter

Topoisomerase I expression in tumors as a biological marker for CPT-11 chemosensitivity in patients with colorectal cancer.

Published in:

Surgery Today, 2011, v. 41, n. 9, p. 1196, doi. 10.1007/s00595-011-4546-7

By:

Ikeguchi, Masahide;
Arai, Yosuke;
Maeta, Yoshihiko;
Ashida, Keigo;
Katano, Kuniyuki;
Wakatsuki, Toshiro

Publication type:

Article

Update on alpha-linolenic acid.

Published in:

Nutrition Reviews, 2008, v. 66, n. 6, p. 326, doi. 10.1111/j.1753-4887.2008.00040.x

By:

Stark, Aliza H.;
Crawford, Michael A.;
Reifen, Ram

Publication type:

Article

Abortive activity of Topoisomerase I: a challenge for genome integrity?

Published in:

Current Genetics, 2019, v. 65, n. 5, p. 1141, doi. 10.1007/s00294-019-00984-w

By:

Jakobsen, Kristoffer Pors;
Andersen, Anni H.;
Bjergbæk, Lotte

Publication type:

Article

Interplay between Top1 and Mms21/Nse2 mediated sumoylation in stable maintenance of long chromosomes.

Published in:

Current Genetics, 2017, v. 63, n. 4, p. 627, doi. 10.1007/s00294-016-0665-4

By:

Mahendrawada, Lakshmi;
Rai, Ragini;
Kothiwal, Deepash;
Laloraya, Shikha

Publication type:

Article

Type 1 diabetes affects topoisomerase I activity and GlcNAcylation in rat organs: Kidney, liver and pancreas.

Published in:

Glycobiology, 2012, v. 22, n. 5, p. 704, doi. 10.1093/glycob/cws008

By:

Levi, Itzhak;
Segev, Yael;
Priel, Esther

Publication type:

Article

Modification of Topoisomerase I Activity by Glucose and by O-Glcnacylation of the Enzyme Protein.

Published in:

Glycobiology, 2007, v. 17, n. 12, p. 1357, doi. 10.1093/glycob/cwm105

By:

Noa Noach;
Yael Segev;
Itzhak Levi;
Shraga Segal;
Esther Priel

Publication type:

Article

In Silico Molecular Docking Approach and In Vitro Antioxidant and Antimicrobial Activity of Physalis angulata L. Extract.

Published in:

Journal of Computational Biophysics & Chemistry, 2024, v. 23, n. 2, p. 161, doi. 10.1142/S2737416523500564

By:

Wardhani, Riuh;
Darsih, Cici;
Iwansyah, Ade Chandra;
Indriati, Ashri;
Hamid, Hazrulrizawati Abdul;
Husain, Dirayah Rauf

Publication type:

Article

Design, Synthesis, Spectroscopic Characterization, Molecular Docking and Biological Evaluation of 9H-Carbazole Linked 4-Nitrophenol: A DFT Approach.

Published in:

Journal of Computational Biophysics & Chemistry, 2022, v. 21, n. 8, p. 909, doi. 10.1142/S2737416522500259

By:

Ragavan, Joseph Iruthayaraj;
Anbarasan, Ponnusamy M.;
Arunkumar, Ammasi;
Ibrahim, A.

Publication type:

Article

获能前后水牛精子的差异蛋白质组分析.

Published in:

Journal of Henan Agricultural Sciences, 2022, v. 51, n. 5, p. 140, doi. 10.15933/j.cnki.1004-3268.2022.05.015

By:

刘润峰;
候振;
黄星晨;
肖凯;
杨潍菡;
张俊俊;
付强

Publication type:

Article

杨梅枯萎病拮抗内生菌的分离及其抑菌机制研究.

Published in:

Journal of Henan Agricultural Sciences, 2021, v. 50, n. 4, p. 96, doi. 10.15933/j.cnki.1004-3268.2021.04.013

By:

曹鹏飞;
刘青娥

Publication type:

Article

Successful Desensitization to Irinotecan in a Patient with Metastatic Esophageal Squamous Cell Carcinoma and a History of Anaphylaxis in Response to Irinotecan—Case Report and Literature Review.

Published in:

Journal of Clinical Medicine, 2024, v. 13, n. 24, p. 7824, doi. 10.3390/jcm13247824

By:

Ali, Selda;
Nedelcu, Denisa-Mihaela;
Serescu, Radu;
Bumbăcea, Roxana Silvia

Publication type:

Article

4 + n-dimensional water and waves on four and eleven-dimensional manifolds.

Published in:

Open Physics, 2018, v. 16, n. 1, p. 463, doi. 10.1515/phys-2018-0063

By:

Sepehri, Alireza;
Fioranelli, Massimo

Publication type:

Article

CBFA1 and topoisomerase I mRNA levels decline during cellular aging of human trabecular osteoblasts.

Published in:

2000

By:

Christiansen, Mette;
Kveiborg, Marie;
Christiansen, M;
Kveiborg, M;
Kassem, M;
Clark, B F;
Rattan, S I

Publication type:

journal article

Characterisation and antiproliferative activity of irinotecan and sulphonatocalixarene inclusion complex.

Published in:

Supramolecular Chemistry, 2011, v. 23, n. 6, p. 441, doi. 10.1080/10610278.2010.544736

By:

Wang, Guo-Song;
Zhang, Heng-Yi;
Li, Dong;
Wang, Pu-Yue;
Liu, Yu

Publication type:

Article

Anthocyanin-Rich Berry Extracts Affect SN-38-Induced Response: A Comparison of Non-Tumorigenic HCEC-1CT and HCT116 Colon Carcinoma Cells.

Published in:

Antioxidants, 2024, v. 13, n. 7, p. 846, doi. 10.3390/antiox13070846

By:

Schmutz, Cornelia;
Plaza, Crepelle;
Steiger, Franziska;
Stoirer, Natascha;
Gufler, Judith;
Pahlke, Gudrun;
Will, Frank;
Berger, Walter;
Marko, Doris

Publication type:

Article

Rapid, DNA-induced interface swapping by DNA gyrase.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.86722

By:

Germe, Thomas R. M.;
Bush, Natassja G.;
Baskerville, Victoria M.;
Saman, Dominik;
Benesch, Justin L. P.;
Maxwell, Anthony

Publication type:

Article

Copper Complex Cu(SBCM)2 Induced Cell Cycle Arrest and Apoptosis Towards Oestrogen-Receptor Positive MCF-7 Breast Cancer Cells.

Published in:

Malaysian Journal of Medicine & Health Sciences, 2019, v. 15, p. 13

By:

Jhi Biau Foo;
Li Shan Ng;
Ji Hui Lim;
Pau Xien Tan;
Yan Zhi Lor;
Jason Siau Ee Loo;
May Lee Low;
Lee Chin Chan;
Chaw Yee Beh;
Yin Sim Tor;
Yazan, Latifah Saiful;
Chee Wun How

Publication type:

Article

Topological Process of Splitting DNA-Links.

Published in:

Biomath, 2022, v. 11, n. 1, p. 1, doi. 10.55630/j.biomath.2022.03.288

By:

Mohamad, Abdul Adheem;
Tsukasa Yashiro

Publication type:

Article

Comparison of biomarker expression in oral lichen planus and oral lichenoid lesions.

Published in:

Advances in Clinical & Experimental Medicine, 2022, v. 31, n. 12, p. 1327, doi. 10.17219/acem/152429

By:

Radwan-Oczko, Małgorzata;
Lis-Nawara, Anna;
Hałoń, Agnieszka;
Bar, Julia

Publication type:

Article

DNA topoisomerases as targets for anticancer drugs.

Published in:

Journal of Clinical Pharmacy & Therapeutics, 2001, v. 26, n. 6, p. 405, doi. 10.1046/j.1365-2710.2001.00368.x

By:

Z.;
Topcu, Z.

Publication type:

Article

Artemisinin Derivatives Target Topoisomerase 1 and Cause DNA Damage in Silico and in Vitro.

Published in:

Frontiers in Pharmacology, 2017, p. 1, doi. 10.3389/fphar.2017.00711

By:

Kadioglu, Onat;
Ariel Chan;
Cong Ling Qiu, Alena;
Kam Wai Wong, Vincent;
Colligs, Vanessa;
Wecklein, Sabine;
Rached, Halima Freund-Henni;
Efferth, Thomas;
Wen-Luan Wendy Hsiao

Publication type:

Article

Identification of Hub Genes Associated With Immune Infiltration and Predict Prognosis in Hepatocellular Carcinoma via Bioinformatics Approaches.

Published in:

Frontiers in Genetics, 2021, v. 11, p. N.PAG, doi. 10.3389/fgene.2020.575762

By:

Chen, Huaping;
Wu, Junrong;
Lu, Liuyi;
Hu, Zuojian;
Li, Xi;
Huang, Li;
Zhang, Xiaolian;
Chen, Mingxing;
Qin, Xue;
Xie, Li

Publication type:

Article

Design, synthesis, and characterization of oxadiazolopyrazine analogs with application as anticancer agents.

Published in:

Journal of the Chinese Chemical Society, 2022, v. 69, n. 2, p. 375, doi. 10.1002/jccs.202100438

By:

Chen, Wei‐Chia;
Chen, Chia‐Ling;
Chang, Tzu‐Ting;
Hsieh, Feng‐Chun;
Chen, Wei‐Sheng;
Li, Wen‐Shan

Publication type:

Article

One‐pot synthesis of novel benzimidazoles with a naphthalene moiety as antimicrobial agents and molecular docking studies.

Published in:

Journal of the Chinese Chemical Society, 2021, v. 68, n. 2, p. 374, doi. 10.1002/jccs.202000125

By:

Ersan, Ronak Haj;
Yuksel, Ahmet;
Ertan‐Bolelli, Tugba;
Dogen, Aylin;
Burmaoglu, Serdar;
Algul, Oztekin

Publication type:

Article

Cover: Journal of the Chinese Chemical Society 7/2020.

Published in:: Journal of the Chinese Chemical Society, 2020, v. 67, n. 7, p. 1133, doi. 10.1002/jccs.202080701
Publication type:: Article

Molecular docking study and structure‐based design of novel camptothecin analogues used as topoisomerase I inhibitor.

Published in:

Journal of the Chinese Chemical Society, 2018, v. 65, n. 10, p. 1160, doi. 10.1002/jccs.201700314

By:

Arthur, David Ebuka;
Uzairu, Adamu

Publication type:

Article

Elevation of IgG levels is a serological indicator for pulmonary fibrosis in systemic sclerosis with anti-topoisomerase I antibodies and those with anticentromere antibody.

Published in:

Clinical & Experimental Dermatology, 2008, v. 33, n. 3, p. 329, doi. 10.1111/j.1365-2230.2007.02678.x

By:

Komura, K.;
Yanaba, K.;
Ogawa, F.;
Shimizu, K.;
Takehara, K.;
Sato, S.

Publication type:

Article

Structural insights into human topoisomerase 3β DNA and RNA catalysis and nucleic acid gate dynamics.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-55959-y

By:

Yang, Xi;
Chen, Xuemin;
Yang, Wei;
Pommier, Yves

Publication type:

Article

A synthetic methylotroph achieves accelerated cell growth by alleviating transcription-replication conflicts.

Published in:

Nature Communications, 2025, v. 16, p. 1, doi. 10.1038/s41467-024-55502-5

By:

Meng, Xin;
Hu, Guipeng;
Li, Xiaomin;
Gao, Cong;
Song, Wei;
Wei, Wanqing;
Wu, Jing;
Liu, Liming

Publication type:

Article

Osmotic disruption of chromatin induces Topoisomerase 2 activity at sites of transcriptional stress.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-54567-6

By:

Gittens, William H.;
Allison, Rachal M.;
Wright, Ellie M.;
Brown, George G. B.;
Neale, Matthew J.

Publication type:

Article

PARP1-dependent DNA-protein crosslink repair.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-50912-x

By:

Fábián, Zita;
Kakulidis, Ellen S.;
Hendriks, Ivo A.;
Kühbacher, Ulrike;
Larsen, Nicolai B.;
Oliva-Santiago, Marta;
Wang, Junhui;
Leng, Xueyuan;
Dirac-Svejstrup, A. Barbara;
Svejstrup, Jesper Q.;
Nielsen, Michael L.;
Caldecott, Keith;
Duxin, Julien P.

Publication type:

Article

Inhibition of topoisomerase 2 catalytic activity impacts the integrity of heterochromatin and repetitive DNA and leads to interlinks between clustered repeats.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-49816-7

By:

Amoiridis, Michalis;
Verigos, John;
Meaburn, Karen;
Gittens, William H.;
Ye, Tao;
Neale, Matthew J.;
Soutoglou, Evi

Publication type:

Article