Works matching DE "DNA repair"

Results: 5000

Colorectal Cancers and Microsatellite Instability.

Published in:

Turkish Journal of Oncology / Türk Onkoloji Dergisi, 2025, v. 40, n. 1, p. 83, doi. 10.5505/tjo.2024.4477

By:

ESMKHANI, Sahra;
EMREM, Mustafa;
ŞAHIN, Ali;
BABAYEV, Hüseyn;
ZEYNELOĞLU, Can;
ARDIÇLI, Sena;
YAZICI, Hilal;
YAZICI, Hülya

Publication type:

Article

Investigation of mRNA expression levels of DNA damage response genes in Merkel Cell Polyomavirus-positive Merkel Cell Carcinoma: a pilot study.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02651-8

By:

Passerini, Sara;
Fracella, Matteo;
Ferlosio, Amedeo;
Moens, Ugo;
Scagnolari, Carolina;
Antonelli, Guido;
Ciotti, Marco;
Pietropaolo, Valeria

Publication type:

Article

Study on the molecular mechanism of UBA52 and BARD1 regulating hepatocellular carcinoma through the PI3 K/AKT signaling pathway.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02600-5

By:

Yang, Chenrui;
Zhang, Yanzhong;
Liu, Yajuan;
Wu, Xiaoyong;
Sun, Fangyuan

Publication type:

Article

Slightly increased level of DNA migration in the comet assay: does statistical significance equal biological significance? Open Access.

Published in:

Mutagenesis, 2025, v. 40, n. 2, p. 99, doi. 10.1093/mutage/geaf004

By:

Møller, Peter;
Collins, Andrew;
Rodriguez-Garraus, Adriana;
Langie, Sabine A S;
Godschalk, Roger;
Azqueta, Amaya

Publication type:

Article

A pooled analysis of host factors that affect nucleotide excision repair in humans Open Access.

Published in:

Mutagenesis, 2025, v. 40, n. 2, p. 137, doi. 10.1093/mutage/geae028

By:

Zheng, Congying;
Shaposhnikov, Sergey;
Collins, Andrew;
Brunborg, Gunnar;
Azqueta, Amaya;
Langie, Sabine A S;
Dusinska, Maria;
Slyskova, Jana;
Vodicka, Pavel;
Schooten, Frederik-Jan van;
Bonassi, Stefano;
Milic, Mirta;
Orlow, Irene;
Godschalk, Roger

Publication type:

Article

Elucidating the genetic mechanisms governing cytosine base editing outcomes through CRISPRi screens.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-59948-z

By:

Gu, Sifeng;
Bodai, Zsolt;
Anderson, Rachel A.;
So, Hei Yu Annika;
Cowan, Quinn T.;
Komor, Alexis C.

Publication type:

Article

Mechanistic understanding of UvrA damage detection and lesion hand-off to UvrB in Nucleotide Excision Repair.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-58670-0

By:

Genta, Marianna;
Ferrara, Giulia;
Capelli, Riccardo;
Rondelli, Diego;
Sertic, Sarah;
Bolognesi, Martino;
Rizzi, Menico;
Rossi, Franca;
Jeruzalmi, David;
Chaves-Sanjuan, Antonio;
Miggiano, Riccardo

Publication type:

Article

Transcriptional and epigenetic rewiring by the NUP98::KDM5A fusion oncoprotein directly activates CDK12.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-59930-9

By:

Troester, Selina;
Eder, Thomas;
Wukowits, Nadja;
Piontek, Martin;
Fernández-Pernas, Pablo;
Schmoellerl, Johannes;
Haladik, Ben;
Manhart, Gabriele;
Allram, Melanie;
Maurer-Granofszky, Margarita;
Scheidegger, Nastassja;
Nebral, Karin;
Superti-Furga, Giulio;
Meisel, Roland;
Bornhauser, Beat;
Valent, Peter;
Dworzak, Michael N.;
Zuber, Johannes;
Boztug, Kaan;
Grebien, Florian

Publication type:

Article

Mutations in NEK1 cause ciliary dysfunction as a novel pathogenic mechanism in amyotrophic lateral sclerosis.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00848-7

By:

Noh, Min-Young;
Oh, Seong-il;
Kim, Young-Eun;
Cha, Sun Joo;
Sung, Wonjae;
Oh, Ki-Wook;
Park, Yurim;
Mun, Ji Young;
Ki, Chang-Seok;
Nahm, Minyeop;
Kim, Seung Hyun

Publication type:

Article

Pyroptosis drives tumor progression and immune evasion in Hepatocellular Carcinoma: a single-cell and spatial transcriptomic study.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02421-6

By:

Tao, Siyu;
Yang, Yunhao

Publication type:

Article

Aflatoxin B<sub>1</sub>‐Induced Hepatic Mutagenesis in Mice Expressing Gene‐Edited Neil1.

Published in:

Environmental & Molecular Mutagenesis, 2025, v. 66, n. 4, p. 144, doi. 10.1002/em.70014

By:

Minko, Irina G.;
Vartanian, Vladimir L.;
Luzadder, Michael M.;
Wang, Yingming;
Fedorov, Lev M.;
McCullough, Amanda K.;
Lloyd, R. Stephen

Publication type:

Article

An evidence-driven classification of nonfiltering ingredients for topical photoprotection Open Access.

Published in:

British Journal of Dermatology, 2025, v. 192, n. 6, p. 1132, doi. 10.1093/bjd/ljaf055

By:

Brown, Anthony;
Passeron, Thierry;
Granger, Corinne;
Gilaberte, Yolanda;
Trullas, Carles;
Piquero-Casals, Jaime;
Leone, Giovanni;
Schalka, Sergio;
Lim, Henry W;
Krutmann, Jean

Publication type:

Article

Reevaluating BED in cervical cancer HDR brachytherapy: source decay and tissue-specific repair significantly impact radiobiological dose.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1407606

By:

Bi, Suyan;
Zhou, Jiaomei;
Xu, Meiling;
Dai, Zhitao

Publication type:

Article

The Poly (ADP‐Ribose) Polymerase‐1 Enzyme Is Overexpressed in Various Solid Canine Tumours: An Immunohistochemical Study.

Published in:

Veterinary & Comparative Oncology, 2025, v. 23, n. 2, p. 267, doi. 10.1111/vco.13053

By:

De Vos, Shana;
Janssen, Simone;
Favril, Sophie;
De Cock, Hilde;
Vynck, Matthijs;
Steenbrugge, Jonas;
De Spiegelaere, Ward;
de Rooster, Hilde

Publication type:

Article

Tolerability Assessment of Orally Administered Paclitaxel With Encequidar in Dogs With Spontaneous Malignancy.

Published in:

Veterinary & Comparative Oncology, 2025, v. 23, n. 2, p. 197, doi. 10.1111/vco.13045

By:

Ziegler, Jordan;
Cawley, Jacob;
Istvan, Stephanie;
Press, Saya;
Stewart, Samuel;
Khanna, Chand;
Fenger, Joelle

Publication type:

Article

A novel lncRNA YIL163C enhances genomic stability and antifungal resistance via the DNA damage response in Saccharomyces cerevisiae.

Published in:

Frontiers in Microbiology, 2025, p. 1, doi. 10.3389/fmicb.2025.1571797

By:

Wang, Xueting;
Li, Xuemei;
Li, Duoyun;
Zhang, Yiying;
Bai, Bing;
Chai, Bao;
Wen, Zewen

Publication type:

Article

Telomeres, the nuclear lamina, and membrane remodeling: Orchestrating meiotic chromosome movements.

Published in:

Journal of Cell Biology, 2025, v. 224, n. 5, p. 1, doi. 10.1083/jcb.202412135

By:

Hiroki Shibuya

Publication type:

Article

Xeroderma Pigmentosam: Case Report of Siblings.

Published in:

International Journal of Clinical Pediatric Dentistry, 2025, v. 18, n. 3, p. 311, doi. 10.5005/jp-journals-10005-3083

By:

Javanaiah, Nagarathna;
Krishnappa, Srinath Sarakanuru;
Srinivas, Hemashree Gottikunte

Publication type:

Article

Tumor break load quantitates structural variant-associated genomic instability with biological and clinical relevance across cancers.

Published in:

NPJ Precision Oncology, 2025, v. 9, n. 1, p. 1, doi. 10.1038/s41698-025-00922-9

By:

Lakbir, Soufyan;
de Wit, Renske;
de Bruijn, Ino;
Kundra, Ritika;
Madupuri, Ramyasree;
Gao, Jianjiong;
Schultz, Nikolaus;
Meijer, Gerrit A.;
Heringa, Jaap;
Fijneman, Remond J. A.;
Abeln, Sanne

Publication type:

Article

Protein Arginine Methyltransferases from Regulatory Function to Clinical Implication in Central Nervous System.

Published in:

Cellular & Molecular Neurobiology, 2025, v. 45, n. 1, p. 1, doi. 10.1007/s10571-025-01546-0

By:

Xie, Bin;
Yu, Jing;
Chen, Chao;
Shen, Ting

Publication type:

Article

The repressor PrtR1 and the global H-NS-like regulators MvaT and MvaV enable the fine-tuning of R-tailocin expression in Pseudomonas protegens.

Published in:

BMC Microbiology, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12866-025-03983-9

By:

Heiman, Clara Margot;
Antar, Hammam;
Fournes, Florian;
Keel, Christoph;
Vacheron, Jordan

Publication type:

Article

O-GlcNAcylation of NONO regulates paraspeckle component assembly and contributes to colon cancer cell proliferation.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02405-z

By:

Kim, Yeolhoe;
Lee, Kyung-Tae;
Kim, Han Byeol;
Jung, Hyeryeon;
Ko, Jeong Yeon;
Kweon, Tae Hyun;
Yadavalli, Hari Chandana;
Seo, Junghwa;
Ji, Suena;
Kim, Yun Ju;
Shin, Donghyuk;
Yang, Seong Wook;
Lee, Myeong Min;
Cho, Jin Won;
Yi, Eugene C.;
Nam, Jin-Wu;
Yang, Won Ho

Publication type:

Article

LSM2 drives glioma progression through alternative splicing dysregulation: a multi-omics approach to identify a potential therapeutic target.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1521608

By:

Yang, Cao;
Ge, Chang;
Zhang, Wenjie;
Xu, Jingxuan

Publication type:

Article

Effects of Airborne Particulate Matter in Biomass Treatment Plants on the Expression of DNA Repair and IL-8 Genes.

Published in:

Applied Sciences (2076-3417), 2025, v. 15, n. 9, p. 4904, doi. 10.3390/app15094904

By:

Zanchi, Noemi;
Franchitti, Elena;
Traversi, Deborah

Publication type:

Article

The Molecular Basis of Pediatric Brain Tumors: A Review with Clinical Implications.

Published in:

Cancers, 2025, v. 17, n. 9, p. 1566, doi. 10.3390/cancers17091566

By:

Antoniades, Elias;
Keffes, Nikolaos;
Vorri, Stamatia;
Tsitouras, Vassilios;
Gkantsinikoudis, Nikolaos;
Tsitsopoulos, Parmenion;
Magras, John

Publication type:

Article

Germline DNA Repair Gene Mutations and Clonal Hematopoiesis (CH) in 24,849 Patients with BRCA-Associated Cancers.

Published in:

Cancers, 2025, v. 17, n. 9, p. 1432, doi. 10.3390/cancers17091432

By:

Marshall, Catherine H.;
Arafa, Ali T.;
Jaeger, Ellen;
Fragkogianni, Stamatina;
Sonnenschein, Anne;
Mauer, Elizabeth;
Gondek, Lukasz P.;
Chao, Calvin;
Luo, Jun;
Antonarakis, Emmanuel S.

Publication type:

Article

Melatonin Mitigates Cd-Induced Growth Repression and RNA m 6 A Hypermethylation by Triggering MMR-Mediated DNA Damage Response.

Published in:

Plants (2223-7747), 2025, v. 14, n. 9, p. 1398, doi. 10.3390/plants14091398

By:

Tang, Zihan;
Wang, Hetong;
Wang, Xianpeng;
Ludlow, Richard A.;
Liu, Zhouli;
Zhang, Min;
Cao, Qijiang;
Liu, Wan;
Zhao, Qiang

Publication type:

Article

The Role of Cavin3 in the Development of Malignant Tumors.

Published in:

Cancer Management & Research, 2025, v. 17, p. 863, doi. 10.2147/CMAR.S515739

By:

Qian, Lei;
Zhang, Ziqian;
Cai, Hongning

Publication type:

Article

MS CETSA deep functional proteomics uncovers DNA repair programs leading to gemcitabine resistance.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-59505-8

By:

Liang, Ying Yu;
Khalid, Khalidah;
Le, Hai Van;
Teo, Hui Min Vivian;
Raitelaitis, Mindaugas;
Gerault, Marc-Antoine;
Lee, Jane Jia Hui;
Lyu, Jiawen;
Chan, Allison;
Jeyasekharan, Anand Devaprasath;
Tam, Wai Leong;
Nordlund, Pär;
Prabhu, Nayana

Publication type:

Article

Genomic and immune profiling of breast cancer brain metastases.

Published in:

Acta Neuropathologica Communications, 2025, v. 13, n. 1, p. 1, doi. 10.1186/s40478-025-02001-3

By:

Van Swearingen, Amanda E. D.;
Lee, Marissa R.;
Rogers, Layne W.;
Sibley, Alexander B.;
Shi, Pixu;
Qin, Xiaodi;
Goodin, Michael;
Seale, Katelyn;
Owzar, Kouros;
Anders, Carey K.

Publication type:

Article

Deciphering ERR family genes as prognostic and immunological biomarkers through pan-cancer analysis with validation in gallbladder cancer.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1525635

By:

Gong, Wanwan;
Wen, Sijia;
Chen, Yu;
Wu, Fan;
Yang, Mengmeng;
Sun, Ping;
Guo, Xingmei;
Li, Meiqin;
Chen, Daozhen;
Zhao, Hui;
Wang, Lei

Publication type:

Article

MSH2 -Mutated Lynch Syndrome With 9 Synchronous Colon and Rectum Adenocarcinomas: An Extremely Rare Case Report.

Published in:

International Journal of Surgical Pathology, 2025, v. 33, n. 4, p. 1062, doi. 10.1177/10668969241295691

By:

Kavus, Haluk;
Dorion, Robert Patrick

Publication type:

Article

The repressor PrtR1 and the global H-NS-like regulators MvaT and MvaV enable the fine-tuning of R-tailocin expression in Pseudomonas protegens.

Published in:

BMC Microbiology, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12866-025-03983-9

By:

Heiman, Clara Margot;
Antar, Hammam;
Fournes, Florian;
Keel, Christoph;
Vacheron, Jordan

Publication type:

Article

Integrated bioinformatic analysis identifies GADD45B as an immune-related prognostic biomarker in skin cutaneous melanoma.

Published in:

Hereditas, 2025, v. 162, n. 1, p. 1, doi. 10.1186/s41065-025-00437-0

By:

Zhang, Qing;
He, Song;
Ji, Zhonghao;
Zhang, Xiwen;
Yuan, Bao;
Liu, Ruirui;
Yang, Yimin;
Ding, Yu

Publication type:

Article

Synergistic effects of retinol and retinyl palmitate in alleviating UVB-induced DNA damage and promoting the homologous recombination repair in keratinocytes.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1562244

By:

Zhong, Jiangming;
Liang, Ling;
Zhao, Nan;
Wang, Jing;
Shu, Peng

Publication type:

Article

Mechanisms of the JNK/p38 MAPK signaling pathway in drug resistance in ovarian cancer.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1533352

By:

Ma, Yu-Ting;
Li, Chan;
Shen, Ying;
You, Wan-Hui;
Han, Ming-Xuan;
Mu, Yi-Fan;
Han, Feng-Juan

Publication type:

Article

The Emerging Role of (p)ppGpp in DNA Repair and Associated Bacterial Survival against Fluoroquinolones.

Published in:

Gene Expression (1052-2166), 2025, v. 24, n. 2, p. 130, doi. 10.14218/GE.2024.00033

By:

Sivapragasam, Smitha

Publication type:

Article

NOVEL PROTEOLYSIS-TARGETING CHIMERA TARGETING RAD51 FOR THE TREATMENT OF TRIPLE-NEGATIVE BREAST CANCER.

Published in:

Journal of Physiology & Pharmacology, 2025, v. 76, n. 2, p. 197, doi. 10.26402/jpp.2025.2.09

By:

KIM, S.;
HWANG, I.;
KIM, D. S.;
CHOI, Y. J.;
JEUNG, E.-B.

Publication type:

Article

Case Report: Two cases of chemotherapy refractory aggressive variant prostate cancer with extreme durable response to PARP inhibitor.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1533627

By:

Jiang, Bohao;
Bi, Yifan;
Chen, Yiming;
Bi, Jianbin;
Deng, Jian;
Zhang, Gejun

Publication type:

Article

Correlation of p53 oligomeric status and its subcellular localization in the presence of the AML-associated NPM mutant.

Published in:

PLoS ONE, 2025, v. 20, n. 5, p. 1, doi. 10.1371/journal.pone.0322096

By:

Holoubek, Aleš;
Strachotová, Dita;
Wolfová, Kateřina;
Otevřelova, Petra;
Belejová, Sára;
Röselová, Pavla;
Benda, Aleš;
Brodská, Barbora;
Herman, Petr

Publication type:

Article

Corrigendum: Inhibition of ATM or ATR in combination with hypo-fractionated radiotherapy leads to a different immunophenotype on transcript and protein level in HNSCC.

Published in:

2025

By:

Meidenbauer, Julia;
Wachter, Matthias;
Schulz, Sebastian R.;
Mostafa, Nada;
Zülch, Lilli;
Frey, Benjamin;
Fietkau, Rainer;
Gaipl, Udo S.;
Jost, Tina

Publication type:

Correction Notice

Inhibition of ATM or ATR in combination with hypo-fractionated radiotherapy leads to a different immunophenotype on transcript and protein level in HNSCC.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2024.1460150

By:

Meidenbauer, Julia;
Wachter, Matthias;
Schulz, Sebastian R.;
Mostafa, Nada;
Zülch, Lilli;
Frey, Benjamin;
Fietkau, Rainer;
Gaipl, Udo S.;
Jost, Tina

Publication type:

Article

MicroRNA‐371–373 cluster and methylome analysis suggests that a subset of 'somatic‐type' malignancies arising in germ cell tumors may originate in yolk sac tumor components.

Published in:

Journal of Pathology, 2025, v. 266, n. 2, p. 160, doi. 10.1002/path.6412

By:

Lobo, João;
Tavares, Nuno Tiago;
Fonseca, Diana;
Jerónimo, Carmen;
Henrique, Rui;
Wyvekens, Nicolas;
Yang, Yiying;
Snuderl, Matija;
Maclean, Fiona;
Gordetsky, Jennifer;
Fletcher, Christopher DM;
Hirsch, Michelle S;
Hornick, Jason L;
Idrees, Muhammad T;
Collins, Katrina;
Warmke, Laura;
Ulbright, Thomas M;
Acosta, Andres M

Publication type:

Article

Genome-Wide Temporal Gene Expression Reveals a Post-Reproductive Shift in the Nematode Caenorhabditis briggsae.

Published in:

Genome Biology & Evolution, 2025, v. 17, n. 4, p. 1, doi. 10.1093/gbe/evaf057

By:

van den Berg, Wouter;
Gupta, Bhagwati P

Publication type:

Article

Structural and mechanistic diversity in p53-mediated regulation of organismal longevity across taxonomical orders.

Published in:

PLoS Computational Biology, 2025, v. 21, n. 5, p. 1, doi. 10.1371/journal.pcbi.1012382

By:

Osbourne, Romani;
Thayer, Kelly M.

Publication type:

Article

SLFN11 Deficiency-Induced Gemcitabine Resistance Is Overcome by Agents Targeting the DNA Damage Response in Pancreatic Cancer Cells.

Published in:

Biocell, 2025, v. 49, n. 4, p. 681, doi. 10.32604/biocell.2025.062144

By:

Kim, Jae Hyeong;
Youn, Yuna;
Hwang, Jin-Hyeok

Publication type:

Article

Expression of human 8-oxoguanine DNA glycosylase (hOGG1) in follicular lymphoma.

Published in:

Modern Pathology, 2005, v. 18, n. 11, p. 1512, doi. 10.1038/modpathol.3800461

By:

Sheehan, Andrea M.;
McGregor, David K.;
Patel, Ankita;
Shidham, Vinod;
Chung-Yang Fan;
Chung-Che Chang

Publication type:

Article

Differential expression of DNA nonhomologous end-joining proteins Ku70 and Ku80 in melanoma progression.

Published in:

2002

By:

Korabiowska, Monika;
Tscherny, Michael;
Stachura, Jerzy;
Berger, Hermann;
Cordon-Cardo, Carlos;
Brinck, Ulrich

Publication type:

journal article

Low Genetic Quality Alters Key Dimensions of the Mutational Spectrum.

Published in:

PLoS Biology, 2016, v. 14, n. 3, p. 1, doi. 10.1371/journal.pbio.1002419

By:

Sharp, Nathaniel P.;
Agrawal, Aneil F.

Publication type:

Article

Tel1 and Rif2 Regulate MRX Functions in End-Tethering and Repair of DNA Double-Strand Breaks.

Published in:

PLoS Biology, 2016, v. 14, n. 2, p. 1, doi. 10.1371/journal.pbio.1002387

By:

Cassani, Corinne;
Gobbini, Elisa;
Wang, Weibin;
Niu, Hengyao;
Clerici, Michela;
Sung, Patrick;
Longhese, Maria Pia

Publication type:

Article