Works matching DE "DNA methyltransferases"

Results: 2096

Environmental interpretation of the impact of vehicle emissions on prostate cancer progression.

Published in:

Cancer Cell International, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12935-025-03906-8

By:

An, Bingzheng;
Chen, Shuo;
Zhang, Chen;
Wang, Junyan;
Guo, Zhaoxin;
Gao, Ze

Publication type:

Article

Prenatal stress increases corticosterone levels in offspring by impairing placental glucocorticoid barrier function.

Published in:

PLoS ONE, 2025, v. 20, n. 7, p. 1, doi. 10.1371/journal.pone.0313705

By:

Liu, Can;
Liu, Hongya;
Li, Hongyu;
Yang, Deguang;
Li, Ye;
Wang, Rui;
Zhu, Jiashu;
Ma, Shuqin;
Guan, Suzhen

Publication type:

Article

5-mC DNA methylation in neurodevelopment: from molecular mechanisms to therapeutic implications.

Published in:

Molecular Biology Reports, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s11033-025-10809-4

By:

Huang, Dishu;
Zhao, Wenjie;
Sun, Hong;
Yang, Chen;
Jiang, Li

Publication type:

Article

Recent Insights Into Breast Cancer: Molecular Pathways, Epigenetic Regulation, and Emerging Targeted Therapies.

Published in:

Breast Cancer: Basic & Clinical Research, 2025, p. 1, doi. 10.1177/11782234251355663

By:

Maqsood, Quratulain;
Khan, Muhammad Umer;
Fatima, Tehreem;
Khalid, Sania;
Malik, Zaryab Ikram

Publication type:

Article

Epigenetic agents, zebularine and valproic acid, inhibit the growth of the oral squamous cell carcinoma cell line HSC4 in vitro and in vivo.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02928-y

By:

Takahashi, Shuhei;
Yoshida, Koki;
Paudel, Durga;
Morikawa, Tetsuro;
Uehara, Osamu;
Harada, Fumiya;
Ariwansa, Dedy;
Giri, Sarita;
Sato, Jun;
Nagayasu, Hiroki;
Abiko, Yoshihiro

Publication type:

Article

Decitabine regulates the resistance of HCC to sorafenib through demethylation.

Published in:

Clinical Epigenetics, 2025, v. 17, n. 1, p. 1, doi. 10.1186/s13148-025-01925-w

By:

Zhang, Miao;
Zhou, Xiaolei;
Li, Zhenzhen;
Zhao, TianYu;
Miao, Yu;
Liu, Sen;
Han, Qiaoqiao;
Wang, Libo;
Xu, Yongdeng;
Cui, Tao;
Wang, Ze;
Yi, Xiulin;
Yan, Fengying;
Wang, Xiaoliang

Publication type:

Article

Epigenetic Regulation of Fungicide Resistance in Plant‐Pathogenic Fungi.

Published in:

Plant Pathology, 2025, v. 74, n. 6, p. 1495, doi. 10.1111/ppa.14126

By:

Kumar, Ram

Publication type:

Article

DNA methylation and demethylation in adipocyte biology: roles of DNMT and TET proteins in metabolic disorders.

Published in:

Frontiers in Endocrinology, 2025, p. 1, doi. 10.3389/fendo.2025.1591152

By:

Wu, Lijiao;
Wang, Xiangjin;
Wang, Luling;
Li, Shuyan;
Chen, Qiu

Publication type:

Article

Management of T‐cell malignancies: Bench‐to‐bedside targeting of epigenetic biology.

Published in:

CA: A Cancer Journal for Clinicians, 2025, v. 75, n. 4, p. 282, doi. 10.3322/caac.70001

By:

Sabzevari, Ariana;
Ung, Johnson;
Craig, Jeffrey W.;
Jayappa, Kallesh D.;
Pal, Ipsita;
Feith, David J.;
Loughran, Thomas P.;
O'Connor, Owen A.

Publication type:

Article

Combined Phytochemical Sulforaphane and Dietary Fiber Inulin Contribute to the Prevention of ER-Negative Breast Cancer via PI3K/AKT/MTOR Pathway and Modulating Gut Microbial Composition.

Published in:

Nutrients, 2025, v. 17, n. 12, p. 2023, doi. 10.3390/nu17122023

By:

Wu, Huixin;
Witt, Brittany L.;
van der Pol, William J.;
Morrow, Casey D.;
Duck, Lennard W.;
Tollefsbol, Trygve O.

Publication type:

Article

CircRNA DNA methyltransferase 1 silence inhibits breast cancer development by regulating micoRNA‐485‐3p/zinc finger E‐box binding homeobox 1 axis.

Published in:

Journal of Obstetrics & Gynaecology Research, 2021, v. 47, n. 3, p. 1068, doi. 10.1111/jog.14639

By:

Xie, Chen;
Li, Junyu;
Xu, Chen;
Xiong, Wenmin;
Yuan, Xia

Publication type:

Article

Super-early initiation of temozolomide prolongs the survival of glioblastoma patients without gross-total resection: a retrospective cohort study.

Published in:

Journal of Neuro-Oncology, 2019, v. 144, n. 1, p. 127, doi. 10.1007/s11060-019-03211-1

By:

Jiang, Haihui;
Zeng, Wei;
Ren, Xiaohui;
Cui, Yong;
Li, Mingxiao;
Yang, Kaiyuan;
Elbaroody, Mohammad;
Lin, Song

Publication type:

Article

Cytotoxic synergy between alisertib and carboplatin versus alisertib and irinotecan are inversely dependent on MGMT levels in glioblastoma cells.

Published in:

Journal of Neuro-Oncology, 2019, v. 143, n. 2, p. 231, doi. 10.1007/s11060-019-03164-5

By:

Sak, Müge;
Zumbar, Cory T.;
King, Paul D.;
Li, Xiaohui;
Mifsud, Caroline S.;
Usubalieva, Aisulu;
Anderson, Charles D.;
Chesnick, Hailey M.;
McElroy, Joseph P.;
Chakravarti, Arnab;
Burton, Eric C.;
Lehman, Norman L.

Publication type:

Article

Role of postoperative tumor volume in patients with MGMT-unmethylated glioblastoma.

Published in:

Journal of Neuro-Oncology, 2019, v. 142, n. 3, p. 529, doi. 10.1007/s11060-019-03124-z

By:

Sales, Arthur H. A.;
Bette, Stefanie;
Barz, Melanie;
Huber, Thomas;
Wiestler, Benedikt;
Ryang, Yu-Mi;
Schmidt-Graf, Friederike;
Liesche, Friederike;
Combs, Stephanie E.;
Meyer, Bernhard;
Gempt, Jens

Publication type:

Article

Contrast enhancement predicting survival in integrated molecular subtypes of diffuse glioma: an observational cohort study.

Published in:

Journal of Neuro-Oncology, 2018, v. 139, n. 2, p. 373, doi. 10.1007/s11060-018-2872-y

By:

Hempel, Johann-Martin;
Brendle, Cornelia;
Bender, Benjamin;
Bier, Georg;
Skardelly, Marco;
Gepfner-Tuma, Irina;
Eckert, Franziska;
Ernemann, Ulrike;
Schittenhelm, Jens

Publication type:

Article

Temporal stability of <italic>MGMT</italic> promoter methylation in glioblastoma patients undergoing STUPP protocol.

Published in:

Journal of Neuro-Oncology, 2018, v. 137, n. 2, p. 233, doi. 10.1007/s11060-017-2722-3

By:

O’Regan, C. J.;
Kearney, H.;
Beausang, A.;
Farrell, M. A.;
Brett, F. M.;
Cryan, J. B.;
Loftus, T. E.;
Buckley, P. G.

Publication type:

Article

Prognostic relevance of programmed cell death ligand 1 expression in glioblastoma.

Published in:

Journal of Neuro-Oncology, 2018, v. 136, n. 3, p. 453, doi. 10.1007/s11060-017-2675-6

By:

Lee, Kyu Sang;
Lee, Kyoungyul;
Yun, Sumi;
Moon, Seyoung;
Park, Yujun;
Han, Jung Ho;
Kim, Chae-Yong;
Lee, Hye Seung;
Choe, Gheeyoung

Publication type:

Article

Multi-institutional external validation of a novel glioblastoma prognostic nomogram incorporating MGMT methylation.

Published in:

Journal of Neuro-Oncology, 2017, v. 134, n. 2, p. 331, doi. 10.1007/s11060-017-2529-2

By:

Molitoris, Jason;
Rao, Yuan;
Patel, Rajal;
Kane, Liam;
Badiyan, Shahed;
Gittleman, Haley;
Barnholtz-Sloan, Jill;
Bentzen, Soren;
Kruser, Tim;
Huang, Jiayi;
Mehta, Minesh

Publication type:

Article

MGMT promoter methylation status as a prognostic factor for the outcome of gamma knife radiosurgery for recurrent glioblastoma.

Published in:

Journal of Neuro-Oncology, 2017, v. 133, n. 3, p. 615, doi. 10.1007/s11060-017-2478-9

By:

Kim, Byung;
Kong, Doo-Sik;
Seol, Ho;
Nam, Do-Hyun;
Lee, Jung-Il

Publication type:

Article

MGMT promoter methylation status: time for a frank discussion.

Published in:

2017

By:

Coleman, Niamh;
Bridges, Leslie;
Saran, Frank

Publication type:

Letter

MiR-198 enhances temozolomide sensitivity in glioblastoma by targeting MGMT.

Published in:

Journal of Neuro-Oncology, 2017, v. 133, n. 1, p. 59, doi. 10.1007/s11060-017-2425-9

By:

Nie, Er;
Jin, Xin;
Wu, Weining;
Yu, Tianfu;
Zhou, Xu;
Shi, Zhumei;
Zhang, Junxia;
Liu, Ning;
You, Yongping

Publication type:

Article

Molecular-genetic and clinicopathological prognostic factors in patients with gliomas showing total 1p19q loss: gain of chromosome 19p and histological grade III negatively correlate with patient's prognosis.

Published in:

Journal of Neuro-Oncology, 2017, v. 132, n. 1, p. 119, doi. 10.1007/s11060-016-2344-1

By:

Hayashi, Saeko;
Kitamura, Yohei;
Hirose, Yuichi;
Yoshida, Kazunari;
Sasaki, Hikaru

Publication type:

Article

Impact on prognosis of the regional distribution of MGMT methylation with respect to the CpG island methylator phenotype and age in glioma patients.

Published in:

Journal of Neuro-Oncology, 2015, v. 122, n. 3, p. 441, doi. 10.1007/s11060-015-1738-9

By:

Mur, Pilar;
Rodríguez de Lope, Ángel;
Díaz-Crespo, Francisco;
Hernández-Iglesias, Teresa;
Ribalta, Teresa;
Fiaño, Concepción;
García, Juan;
Rey, Juan;
Mollejo, Manuela;
Meléndez, Bárbara

Publication type:

Article

Prognosis of glioblastoma with faint MGMT methylation-specific PCR product.

Published in:

Journal of Neuro-Oncology, 2015, v. 122, n. 1, p. 179, doi. 10.1007/s11060-014-1701-1

By:

Hsu, Chih-Yi;
Ho, Hsiang-Ling;
Lin, Shih-Chieh;
Chang-Chien, Yi-Chun;
Chen, Ming-Hsiung;
Hsu, Sanford;
Yen, Yu-Shu;
Guo, Wan-You;
Ho, Donald

Publication type:

Article

MGMT promoter methylation in non-neoplastic brain.

Published in:

Journal of Neuro-Oncology, 2015, v. 121, n. 3, p. 459, doi. 10.1007/s11060-014-1663-3

By:

Hsu, Chih-Yi;
Ho, Hsiang-Ling;
Chang-Chien, Yi-Chun;
Chang, Yi-Wen;
Ho, Donald

Publication type:

Article

Anatomical specificity of O6-methylguanine DNA methyltransferase protein expression in glioblastomas.

Published in:

Journal of Neuro-Oncology, 2014, v. 120, n. 2, p. 331, doi. 10.1007/s11060-014-1555-6

By:

Wang, Yinyan;
Fan, Xing;
Zhang, Chuanbao;
Zhang, Tan;
Peng, Xiaoxia;
Li, Shaowu;
Wang, Lei;
Ma, Jun;
Jiang, Tao

Publication type:

Article

IDH1 mutation and MGMT methylation status predict survival in patients with anaplastic astrocytoma treated with temozolomide-based chemoradiotherapy.

Published in:

Journal of Neuro-Oncology, 2014, v. 118, n. 2, p. 377, doi. 10.1007/s11060-014-1443-0

By:

Minniti, Giuseppe;
Scaringi, Claudia;
Arcella, Antonella;
Lanzetta, Gaetano;
Stefano, Domenica;
Scarpino, Stefania;
Bozzao, Alessandro;
Pace, Andrea;
Villani, Veronica;
Salvati, Maurizio;
Esposito, Vincenzo;
Giangaspero, Felice;
Enrici, Riccardo

Publication type:

Article

MGMT promoter methylation in plasma of glioma patients receiving temozolomide.

Published in:

Journal of Neuro-Oncology, 2014, v. 117, n. 2, p. 347, doi. 10.1007/s11060-014-1395-4

By:

Fiano, Valentina;
Trevisan, Morena;
Trevisan, Elisa;
Senetta, Rebecca;
Castiglione, Anna;
Sacerdote, Carlotta;
Gillio-Tos, Anna;
Marco, Laura;
Grasso, Chiara;
Magistrello, Michela;
Tondat, Fabrizio;
Rudà, Roberta;
Cassoni, Paola;
Soffietti, Riccardo;
Merletti, Franco

Publication type:

Article

Outcome-based determination of optimal pyrosequencing assay for MGMT methylation detection in glioblastoma patients.

Published in:

Journal of Neuro-Oncology, 2014, v. 116, n. 3, p. 487, doi. 10.1007/s11060-013-1332-y

By:

Quillien, Véronique;
Lavenu, Audrey;
Sanson, Marc;
Legrain, Michèle;
Dubus, Pierre;
Karayan-Tapon, Lucie;
Mosser, Jean;
Ichimura, Koichi;
Figarella-Branger, Dominique

Publication type:

Article

NDRG1 prognosticates the natural course of disease in WHO grade II glioma.

Published in:

Journal of Neuro-Oncology, 2014, v. 117, n. 1, p. 25, doi. 10.1007/s11060-013-1357-2

By:

Blaes, J.;
Weiler, M.;
Sahm, F.;
Hentschel, B.;
Osswald, M.;
Czabanka, M.;
Thomé, C.;
Schliesser, M.;
Pusch, S.;
Luger, S.;
Winkler, F.;
Radbruch, A.;
Jugold, M.;
Simon, M.;
Steinbach, J.;
Schackert, G.;
Tatagiba, M.;
Westphal, M.;
Tonn, J.;
Gramatzki, D.

Publication type:

Article

Temporal relationship of post-operative radiotherapy with temozolomide and oncologic outcome for glioblastoma.

Published in:

Journal of Neuro-Oncology, 2014, v. 116, n. 2, p. 357, doi. 10.1007/s11060-013-1302-4

By:

Spratt, Daniel;
Folkert, Michael;
Zumsteg, Zachary;
Chan, Timothy;
Beal, Kathryn;
Gutin, Philip;
Pentsova, Elena;
Yamada, Yoshiya

Publication type:

Article

O-methylguanine-DNA methyltransferase (MGMT) immunohistochemistry as a predictor of resistance to temozolomide in primary CNS lymphoma.

Published in:

Journal of Neuro-Oncology, 2013, v. 114, n. 1, p. 135, doi. 10.1007/s11060-013-1162-y

By:

Jiang, Xiaoyin;
Reardon, David;
Desjardins, Annick;
Vredenburgh, James;
Quinn, Jennifer;
Austin, Alan;
Herndon, James;
McLendon, Roger;
Friedman, Henry

Publication type:

Article

The value of temozolomide in combination with radiotherapy during standard treatment for newly diagnosed glioblastoma.

Published in:

Journal of Neuro-Oncology, 2013, v. 112, n. 2, p. 277, doi. 10.1007/s11060-013-1060-3

By:

Park, Chul-Kee;
Lee, Se-Hoon;
Kim, Tae;
Choi, Seung;
Park, Sung-Hye;
Heo, Dae;
Kim, Il;
Jung, Hee-Won

Publication type:

Article

Lack of MGMT promoter hypermethylation in hemangiopericytomas of the central nervous system.

Published in:

2012

By:

Brokinkel, Benjamin;
Peetz-Dienhart, Susanne;
Keyvani, Kathy;
Stummer, Walter;
Paulus, Werner;
Hasselblatt, Martin

Publication type:

Letter

Clinicopathologic and genomic features of gliosarcomas.

Published in:

Journal of Neuro-Oncology, 2012, v. 107, n. 3, p. 643, doi. 10.1007/s11060-011-0790-3

By:

Lee, Dakeun;
Kang, So;
Suh, Yeon-Lim;
Jeong, Ji;
Lee, Jung-Il;
Nam, Do-Hyun

Publication type:

Article

MGMT promoter hypermethylation and its associations with genetic alterations in a series of 350 brain tumors.

Published in:

Journal of Neuro-Oncology, 2012, v. 107, n. 3, p. 617, doi. 10.1007/s11060-011-0787-y

By:

Mellai, Marta;
Monzeglio, Oriana;
Piazzi, Angela;
Caldera, Valentina;
Annovazzi, Laura;
Cassoni, Paola;
Valente, Guido;
Cordera, Susanna;
Mocellini, Cristina;
Schiffer, Davide

Publication type:

Article

O-methylguanine-DNA-methyltransferase promoter methylation assessment by microdissection-assisted methylation-specific PCR and high resolution melting analysis in patients with glioblastomas.

Published in:

Journal of Neuro-Oncology, 2012, v. 106, n. 2, p. 243, doi. 10.1007/s11060-011-0668-4

By:

Yang, Seung-Ho;
Lee, Keun;
Yang, Hea;
Jeon, Byeong;
Lee, Youn;
Nam, Suk;
Chung, Dong-Sup;
Lee, Sang;
Hong, Yong-Kil

Publication type:

Article

LncRNA KCNQ1OT1 promotes the metastasis of ovarian cancer by increasing the methylation of EIF2B5 promoter.

Published in:

Molecular Medicine, 2022, v. 28, n. 1, p. 1, doi. 10.1186/s10020-022-00521-5

By:

He, Si-Li;
Chen, Ya-Ling;
Chen, Qi-Hua;
Tian, Qi;
Yi, Shui-Jing

Publication type:

Article

Hsa_circ_0000119 promoted ovarian cancer development via enhancing the methylation of CDH13 by sponging miR‐142‐5p.

Published in:

Journal of Biochemical & Molecular Toxicology, 2023, v. 37, n. 3, p. 1, doi. 10.1002/jbt.23264

By:

Ma, Guiyan;
Li, Yan;
Meng, Fandong;
Sui, Chengguang;
Wang, Yang;
Cheng, Dali

Publication type:

Article

Targeting H3K9 methyltransferase G9a and its related molecule GLP as a potential therapeutic strategy for cancer.

Published in:

Journal of Biochemical & Molecular Toxicology, 2021, v. 35, n. 3, p. 1, doi. 10.1002/jbt.22674

By:

Rahman, Ziaur;
Bazaz, Mohd. Rabi;
Devabattula, Geetanjali;
Khan, Mohd. Abrar;
Godugu, Chandraiah

Publication type:

Article

Inhibition of NF‐κB is required for oleanolic acid to downregulate PD‐L1 by promoting DNA demethylation in gastric cancer cells.

Published in:

Journal of Biochemical & Molecular Toxicology, 2021, v. 35, n. 1, p. 1, doi. 10.1002/jbt.22621

By:

Lu, Xirong;
Li, Yuyi;
Yang, Wei;
Tao, Minghao;
Dai, Yanmiao;
Xu, Jinkang;
Xu, Qianfei

Publication type:

Article

Nicotinamide N‐methyltransferase expression in SH‐SY5Y human neuroblastoma cells decreases oxidative stress.

Published in:

Journal of Biochemical & Molecular Toxicology, 2020, v. 34, n. 3, p. 1, doi. 10.1002/jbt.22439

By:

Mistry, Rakhee J.;
Klamt, Fábio;
Ramsden, David B.;
Parsons, Richard B.

Publication type:

Article

Evaluation of DNMT1 gene expression profile and methylation of its promoter region in patients with ankylosing spondylitis.

Published in:

Clinical Rheumatology, 2016, v. 35, n. 11, p. 2723, doi. 10.1007/s10067-016-3403-x

By:

Aslani, Saeed;
Mahmoudi, Mahdi;
Garshasbi, Masoud;
Jamshidi, Ahmad;
Karami, Jafar;
Nicknam, Mohammad

Publication type:

Article

Immunohistochemical analysis of the DNA methyltransferase 3b expression is associated with significant improvements in the discrimination of ulcerative colitis-associated neoplastic lesions.

Published in:

Surgery Today, 2013, v. 43, n. 11, p. 1275, doi. 10.1007/s00595-012-0456-6

By:

Ueda, Hirofumi;
Tanaka, Hiroyuki;
Ichikawa, Kazuhito;
Itabashi, Michio;
Kameoka, Shingo;
Fujii, Shigehiko;
Saito, Natsuko;
Kimura, Ryusuke;
Shida, Yosuke;
Fujimori, Yukari;
Ohtake, Shinichirou;
Tomita, Shigeki;
Imura, Johji;
Yasuda, Yoshikazu;
Tanigawa, Nobuhiko;
Uchiyama, Kazuhisa;
Fujimori, Takahiro

Publication type:

Article

Multiregional radiomics features from multiparametric MRI for prediction of MGMT methylation status in glioblastoma multiforme: A multicentre study.

Published in:

2018

By:

Li, Zhi-Cheng;
Bai, Hongmin;
Sun, Qiuchang;
Li, Qihua;
Liu, Lei;
Zou, Yan;
Chen, Yinsheng;
Liang, Chaofeng;
Zheng, Hairong

Publication type:

journal article

Discriminating MGMT promoter methylation status in patients with glioblastoma employing amide proton transfer-weighted MRI metrics.

Published in:

2018

By:

Jiang, Shanshan;
Rui, Qihong;
Wang, Yu;
Heo, Hye-Young;
Zou, Tianyu;
Yu, Hao;
Zhang, Yi;
Wang, Xianlong;
Du, Yongxing;
Wen, Xinrui;
Chen, Fangyao;
Wang, Jihong;
Eberhart, Charles G.;
Zhou, Jinyuan;
Wen, Zhibo

Publication type:

journal article

Different diagnostic values of imaging parameters to predict pseudoprogression in glioblastoma subgroups stratified by MGMT promoter methylation.

Published in:

2017

By:

Yoon, Ra;
Kim, Ho;
Paik, Wooyul;
Shim, Woo;
Kim, Sang;
Kim, Jeong;
Yoon, Ra Gyoung;
Kim, Ho Sung;
Shim, Woo Hyun;
Kim, Sang Joon;
Kim, Jeong Hoon

Publication type:

journal article

DNA Methylation-Based Regulation of Human Bone Marrow-Derived Mesenchymal Stem/Progenitor Cell Chondrogenic Differentiation.

Published in:

Cells Tissues Organs, 2019, v. 207, n. 3-4, p. 115, doi. 10.1159/000502885

By:

Nomura, Yu;
Hara, Emilio Satoshi;
Yoshioka, Yuya;
Nguyen, Há Thi;
Nosho, Shuji;
Komori, Taishi;
Ishibashi, Kei;
Oohashi, Toshitaka;
Ono, Mitsuaki;
Kuboki, Takuo

Publication type:

Article

Erratum to: A Comparative Study on the In Vitro Effects of the DNA Methyltransferase Inhibitor 5-Azacytidine (5-AzaC) in Breast/Mammary Cancer of Different Mammalian Species.

Published in:

2016

By:

Harman, Rebecca;
Curtis, Theresa;
Argyle, David;
Coonrod, Scott;
Walle, Gerlinde

Publication type:

Erratum

A Comparative Study on the In Vitro Effects of the DNA Methyltransferase Inhibitor 5-Azacytidine (5-AzaC) in Breast/Mammary Cancer of Different Mammalian Species.

Published in:

Journal of Mammary Gland Biology & Neoplasia, 2016, v. 21, n. 1/2, p. 51, doi. 10.1007/s10911-016-9350-y

By:

Harman, Rebecca;
Curtis, Theresa;
Argyle, David;
Coonrod, Scott;
Van de Walle, Gerlinde

Publication type:

Article