Works about DNA demethylation

Results: 660

DNA methylation and demethylation in adipocyte biology: roles of DNMT and TET proteins in metabolic disorders.

Published in:

Frontiers in Endocrinology, 2025, p. 1, doi. 10.3389/fendo.2025.1591152

By:

Wu, Lijiao;
Wang, Xiangjin;
Wang, Luling;
Li, Shuyan;
Chen, Qiu

Publication type:

Article

Exposing the DNA methylation-responsive compartment of the leukaemic genome in T-ALL cell lines support its potential as a novel therapeutic target in T-ALL.

Published in:

Clinical Epigenetics, 2025, v. 17, n. 1, p. 1, doi. 10.1186/s13148-025-01915-y

By:

Bensberg, Maike;
Selimović-Pašić, Aida;
Haglund, Lisa;
Goldmann, Júlia;
Hellberg, Sandra;
Nestor, Colm E.

Publication type:

Article

Genome-Wide Analysis of the EIN3/EIL Transcription Factors in Osmanthus fragrans and Their Stress Response to Azacytidine (AZA) and Ethylene (ETH) Treatment.

Published in:

Horticulturae, 2025, v. 11, n. 6, p. 572, doi. 10.3390/horticulturae11060572

By:

Pan, Dou;
Xu, Chun;
Ma, Wanlu;
Zhu, Xinyi;
Yu, Qiangjun;
Zhang, Yingting;
Yang, Jie;
Zeng, Xiangling;
Cai, Xuan;
Zou, Jingjing

Publication type:

Article

Effects of 5-azacytidine-induced DNA demethylation on polyketide synthase gene expression in larvae of sea urchin Strongylocentrotus intermedius.

Published in:

Biotechnology Letters, 2016, v. 38, n. 12, p. 2035, doi. 10.1007/s10529-016-2191-3

By:

Ageenko, N.;
Kiselev, K.;
Tyunin, A.

Publication type:

Article

Ferulic Acid Protects Human Lens Epithelial Cells Against UVA‐Induced Oxidative Damage by Downregulating the DNA Demethylation of the Keap1 Promoter.

Published in:

Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 11, p. 1, doi. 10.1002/jbt.70031

By:

Ling, Xinru;
Zhu, Lei;
Yan, Yuling;
Qian, Haocheng;
Kang, Zhen;
Ye, Wei;
Xie, Zhenggao;
Xue, Chunyan

Publication type:

Article

Inhibition of NF‐κB is required for oleanolic acid to downregulate PD‐L1 by promoting DNA demethylation in gastric cancer cells.

Published in:

Journal of Biochemical & Molecular Toxicology, 2021, v. 35, n. 1, p. 1, doi. 10.1002/jbt.22621

By:

Lu, Xirong;
Li, Yuyi;
Yang, Wei;
Tao, Minghao;
Dai, Yanmiao;
Xu, Jinkang;
Xu, Qianfei

Publication type:

Article

Concomitant loss of TET2 and TET3 results in T cell expansion and genomic instability in mice.

Published in:

Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-07312-0

By:

Gioulbasani, Marianthi;
Äijö, Tarmo;
Liu, Siyao;
Montgomery, Stephanie A.;
Montgomery, Nathan D.;
Corcoran, David;
Tsagaratou, Ageliki

Publication type:

Article

TNC upregulation promotes glioma tumourigenesis through TDG-mediated active DNA demethylation.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-02098-w

By:

Xu, Hongyu;
Long, Shengrong;
Xu, Chengshi;
Li, Zhengwei;
Chen, Jincao;
Yang, Bin;
He, Yongze;
Xu, Ziyue;
Li, Zhiqiang;
Wei, Wei;
Li, Xiang

Publication type:

Article

Methylation in cornea and corneal diseases: a systematic review.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-01935-2

By:

Xia, Yutong;
Chen, Kuangqi;
Yang, Qianjie;
Chen, Zhitong;
Jin, Le;
Zhang, Liyue;
Yu, Xin;
Wang, Liyin;
Xie, Chen;
Zhao, Yuan;
Shen, Ye;
Tong, Jianping

Publication type:

Article

Genome-Wide Identification and Drought-Responsive Functional Analysis of the GST Gene Family in Potato (Solanum tuberosum L.).

Published in:

Antioxidants, 2025, v. 14, n. 2, p. 239, doi. 10.3390/antiox14020239

By:

Shi, Ningfan;
Fan, Youfang;
Zhang, Wei;
Zhang, Zhijia;
Pu, Zhuanfang;
Li, Zhongrun;
Hu, Lijun;
Bi, Zhenzhen;
Yao, Panfeng;
Liu, Yuhui;
Liu, Zhen;
Bai, Jiangping;
Sun, Chao

Publication type:

Article

Pharmacologic Ascorbate and DNMT Inhibitors Increase DUOX Expression and Peroxide-Mediated Toxicity in Pancreatic Cancer.

Published in:

Antioxidants, 2023, v. 12, n. 9, p. 1683, doi. 10.3390/antiox12091683

By:

Steers, Garett J.;
O'Leary, Brianne R.;
Du, Juan;
Wagner, Brett A.;
Carroll, Rory S.;
Domann, Frederick E.;
Goswami, Prabhat C.;
Buettner, Garry R.;
Cullen, Joseph J.

Publication type:

Article

Oxidative DNA Damage and Repair: Mechanisms, Mutations, and Relation to Diseases.

Published in:

Antioxidants, 2023, v. 12, n. 8, p. 1623, doi. 10.3390/antiox12081623

By:

Roginskaya, Marina;
Razskazovskiy, Yuriy

Publication type:

Article

Epigenetic Regulation of IFI44L Expression in Monocytes Affects the Functions of Monocyte-Derived Dendritic Cells in Systemic Lupus Erythematosus.

Published in:

2022

By:

Luo, Shuaihantian;
Wu, Ruifang;
Li, Qianwen;
Zhang, Guiying

Publication type:

journal article

Epigenetic in DNA Methylation and Metabolic Syndrome.

Published in:

Malaysian Journal of Medicine & Health Sciences, 2022, v. 18, p. 101

By:

Hastuti, Pramudji;
Beandrade, Maya Uzia

Publication type:

Article

Characterization of DNA hydroxymethylation profile in cervical cancer.

Published in:

Artificial Cells, Nanomedicine & Biotechnology, 2019, v. 47, n. 1, p. 2706, doi. 10.1080/21691401.2019.1634578

By:

Wang, Jing;
Su, Yi;
Tian, Yongju;
Ding, Yan;
Wang, Xiuli

Publication type:

Article

Tet1-mediated DNA demethylation regulates neuronal cell death induced by oxidative stress.

Published in:

Scientific Reports, 2015, p. 7645, doi. 10.1038/srep07645

By:

Xin, Yong-Juan;
Yuan, Bo;
Yu, Bin;
Wang, Yu-Qing;
Wu, Jia-Jia;
Zhou, Wen-Hao;
Qiu, Zilong

Publication type:

Article

Validation of microinjection methods for generating knockout mice by CRISPR/ Cas-mediated genome engineering.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep04513

By:

Takuro Horii;
Yuji Arai;
Miho Yamazaki;
Sumiyo Morita;
Mika Kimura;
Masahiro Itoh;
Yumiko Abe;
Izuho Hatada

Publication type:

Article

Active DNA demethylation is required for complete imprint erasure in primordial germ cells.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep03658

By:

Yuki Kawasaki;
Jiyoung Lee;
Ayumi Matsuzawa;
Takashi Kohda;
Tomoko Kaneko-Ishino;
Fumitoshi Ishino

Publication type:

Article

Pulrodemstat, a selective inhibitor of KDM1A, suppresses head and neck squamous cell carcinoma growth by triggering apoptosis.

Published in:

BMC Pharmacology & Toxicology, 2024, v. 25, n. 1, p. 1, doi. 10.1186/s40360-024-00807-w

By:

Jiang, Cheng;
Weng, Xiaofeng;
Chen, Yuqing;
Yang, Junjun

Publication type:

Article

Anticancer effects of zinc ion-mediated DNA demethylation in oesophageal squamous cell carcinoma.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1559675

By:

Zhou, Bin;
Wang, Changchun;
Huang, Yueyu;
Yang, Xuping;
Ye, Ting;
Shen, Lize;
Lv, Qiaoli;
Mao, Weimin;
Zhao, An

Publication type:

Article

Plant polysaccharides influence tumor development based on epigenetics: a review.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1588857

By:

Li, Cong;
Hu, Yuao;
Yang, Hua

Publication type:

Article

TET2 Protects against oxLDL-Induced HUVEC Dysfunction by Upregulating the CSE/H<sub>2</sub>S System.

Published in:

Frontiers in Pharmacology, 2017, p. 1, doi. 10.3389/fphar.2017.00486

By:

Juan Peng;
Zhi-Han Tang;
Zhong Ren;
Bei He;
Yun Zeng;
Lu-Shan Liu;
Zuo Wang;
Dang-Heng Wei;
Xi-Long Zheng;
Zhi-Sheng Jiang

Publication type:

Article

TET2 Function in Hematopoietic Malignancies, Immune Regulation, and DNA Repair.

Published in:

Frontiers in Oncology, 2019, p. N.PAG, doi. 10.3389/fonc.2019.00210

By:

Feng, Yimei;
Li, Xiaoping;
Cassady, Kaniel;
Zou, Zhongmin;
Zhang, Xi

Publication type:

Article

Decitabine Induces Change of Biological Traits in Myelodysplastic Syndromes via FOXO1 Activation.

Published in:

Frontiers in Genetics, 2021, v. 11, p. N.PAG, doi. 10.3389/fgene.2020.603956

By:

Zhang, Zheng;
Jia, Yan;
Xv, Feng;
Song, Lu-xi;
Shi, Lei;
Guo, Juan;
Chang, Chun-kang

Publication type:

Article

DNA Methylation and Demethylation Are Regulated by Functional DNA Methyltransferases and DnTET Enzymes in Diuraphis noxia.

Published in:

Frontiers in Genetics, 2020, v. 11, p. 1, doi. 10.3389/fgene.2020.00452

By:

du Preez, Pieter H.;
Breeds, Kelly;
Burger, N. Francois V.;
Swiegers, Hendrik W.;
Truter, J. Christoff;
Botha, Anna-Maria

Publication type:

Article

Impact of DNA Demethylases on the DNA Methylation and Transcription of Arabidopsis NLR Genes.

Published in:

Frontiers in Genetics, 2020, v. 11, p. 1, doi. 10.3389/fgene.2020.00460

By:

Kong, Weiwen;
Xia, Xue;
Wang, Qianqian;
Liu, Li-Wei;
Zhang, Shengwei;
Ding, Li;
Liu, Aixin;
La, Honggui

Publication type:

Article

Mechanical force inhibited hPDLSCs proliferation with the downregulation of MIR31HG via DNA methylation.

Published in:

Oral Diseases, 2021, v. 27, n. 5, p. 1268, doi. 10.1111/odi.13637

By:

Han, Yineng;
Yang, Qiaolin;
Huang, Yiping;
Li, Xiaobei;
Zhu, Yunyan;
Jia, Lingfei;
Zheng, Yunfei;
Li, Weiran

Publication type:

Article

DNA methylation profile in patients with indolent systemic mastocytosis.

Published in:

Clinical & Translational Allergy, 2021, v. 11, n. 9, p. 1, doi. 10.1002/clt2.12074

By:

Górska, Aleksandra;
Jabłońska, Ewa;
Reszka, Edyta;
Niedoszytko, Marek;
Lange, Magdalena;
Gruchała‐Niedoszytko, Marta;
Jarczak, Justyna;
Strapagiel, Dominik;
Górska‐Ponikowska, Magdalena;
Bastian, Paulina;
Pelikant‐Małecka, Iwona;
Kalinowski, Leszek;
Nedoszytko, Bogusław

Publication type:

Article

Smoking, Methylation at AHRR, and Recidivism Risk in a Community Correction Sample of Individuals at High Risk for Recidivism.

Published in:

2015

By:

Gunter, Tracy D.;
Philibert, Robert A.

Publication type:

journal article

Nitric oxide inhibits ten-eleven translocation DNA demethylases to regulate 5mC and 5hmC across the genome.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-56928-1

By:

Palczewski, Marianne B.;
Kuschman, Hannah Petraitis;
Hoffman, Brian M.;
Kathiresan, Venkatesan;
Yang, Hao;
Glynn, Sharon A.;
Wilson, David L.;
Kool, Eric T.;
Montfort, William R.;
Chang, Jenny;
Petenkaya, Aydolun;
Chronis, Constantinos;
Cundari, Thomas R.;
Sappa, Sushma;
Islam, Kabirul;
McVicar, Daniel W.;
Fan, Yu;
Chen, Qingrong;
Meerzaman, Daoud;
Sierk, Michael

Publication type:

Article

Thymine DNA glycosylase combines sliding, hopping, and nucleosome interactions to efficiently search for 5-formylcytosine.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-53497-7

By:

Schnable, Brittani L.;
Schaich, Matthew A.;
Roginskaya, Vera;
Leary, Liam P.;
Weaver, Tyler M.;
Freudenthal, Bret D.;
Drohat, Alexander C.;
Van Houten, Bennett

Publication type:

Article

Pramel15 facilitates zygotic nuclear DNMT1 degradation and DNA demethylation.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-51614-0

By:

Tan, Jiajun;
Li, Yingfeng;
Li, Xiang;
Zhu, Xiaoxiao;
Liu, Liping;
Huang, Hua;
Wei, Jiahua;
Wang, Hailing;
Tian, Yong;
Wang, Zhigao;
Zhang, Zhuqiang;
Zhu, Bing

Publication type:

Article

iPS cell generation-associated point mutations include many C > T substitutions via different cytosine modification mechanisms.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-49335-5

By:

Araki, Ryoko;
Suga, Tomo;
Hoki, Yuko;
Imadome, Kaori;
Sunayama, Misato;
Kamimura, Satoshi;
Fujita, Mayumi;
Abe, Masumi

Publication type:

Article

Azacytidine Induced Epigenetic Variations Improve Fruit Quality and Yield in Tomato Grown under Soil Conditions.

Published in:

Pakistan Journal of Agricultural Sciences, 2024, v. 61, n. 4, p. 1061, doi. 10.21162/PAKJAS/24.325

By:

Khan, Zahid Ahmad;
Saleem, Aiman;
Imtiaz, Hifza;
Ahmad, Raza;
Sajjad, Yasar;
Bilal, Muhammad;
Shah, Shahid Masood;
Khan, Abdul Rehman

Publication type:

Article

AKT signaling is associated with epigenetic reprogramming via the upregulation of TET and its cofactor, alpha-ketoglutarate during iPSC generation.

Published in:

Stem Cell Research & Therapy, 2021, v. 12, n. 1, p. 1, doi. 10.1186/s13287-021-02578-1

By:

Sekita, Yoichi;
Sugiura, Yuki;
Matsumoto, Akari;
Kawasaki, Yuki;
Akasaka, Kazuya;
Konno, Ryo;
Shimizu, Momoka;
Ito, Toshiaki;
Sugiyama, Eiji;
Yamazaki, Terushi;
Kanai, Eriko;
Nakamura, Toshinobu;
Suematsu, Makoto;
Ishino, Fumitoshi;
Kodera, Yoshio;
Kohda, Takashi;
Kimura, Tohru

Publication type:

Article

A context dependent role for DNA methylation in bivalves.

Published in:

Briefings in Functional Genomics, 2014, v. 13, n. 3, p. 217, doi. 10.1093/bfgp/elt054

By:

Gavery, Mackenzie R.;
Roberts, Steven B.

Publication type:

Article

TET proteins: on the frenetic hunt for new cytosine modifications.

Published in:

Briefings in Functional Genomics, 2013, v. 12, n. 3, p. 191, doi. 10.1093/bfgp/elt010

By:

Delatte, Benjamin;
Fuks, François

Publication type:

Article

High glucose induces podocyte epithelial‑to‑mesenchymal transition by demethylation‑mediated enhancement of MMP9 expression.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 4, p. 5642, doi. 10.3892/mmr.2018.8554

By:

Ling, Li;
Chen, Libo;
Zhang, Changning;
Gui, Shuyan;
Zhao, Haiyan;
Li, Zhengzhang

Publication type:

Article

Methylation status of the promoter region of the human frizzled 9 gene in acute myeloid leukemia.

Published in:

Molecular Medicine Reports, 2016, v. 14, n. 2, p. 1339, doi. 10.3892/mmr.2016.5387

By:

YINGJIE ZHANG;
QI JIANG;
XIAOLIN KONG;
LILI YANG;
WANZHEN HU;
CHENGFANG LV;
YINGHUA LI

Publication type:

Article

Inhibitor of DNA binding 4 functions as a tumor suppressor and is targetable by 5-aza-2'-deoxycytosine with potential therapeutic significance in Burkitt's lymphoma.

Published in:

Molecular Medicine Reports, 2016, v. 13, n. 2, p. 269, doi. 10.3892/mmr.2015.4640

By:

XIAN-ZHENG GAO;
WU-GAN ZHAO;
GUAN-NAN WANG;
MEI-YING CUI;
YANG-RUI ZHANG;
WEN-CAI LI

Publication type:

Article

MicroRNA-10b suppresses the migration and invasion of chondrosarcoma cells by targeting brain-derived neurotrophic factor.

Published in:

Molecular Medicine Reports, 2016, v. 13, n. 1, p. 441, doi. 10.3892/mmr.2015.4506

By:

ABUDUNAIBI AILI;
YONG CHEN;
HONGQI ZHANG

Publication type:

Article

Differential expression of stromal aromatase in obese females is regulated by DNA methylation.

Published in:

Molecular Medicine Reports, 2014, v. 10, n. 2, p. 887, doi. 10.3892/mmr.2014.2275

By:

XIAN-CHENG ZENG;
XIANG AO;
HAI-FENG YANG;
GUANG-XIAN ZHANG;
WEN-HONG LI;
QI-LONG LIU;
YUE-LIANG TANG;
YI-CHENG XIE;
WEN-GUANG HE;
YAN-NIAN HUANG;
LEI ZHANG;
RONG-JIANG LI

Publication type:

Article

Host DNA Demethylation Induced by DNMT1 Inhibition Up-Regulates Antiviral OASL Protein during Influenza a Virus Infection.

Published in:

Viruses (1999-4915), 2023, v. 15, n. 8, p. 1646, doi. 10.3390/v15081646

By:

Zhao, Zhiyan;
Li, Jing;
Feng, Ye;
Kang, Xiaoping;
Li, Yuchang;
Chen, Yuehong;
Li, Wei;
Yang, Wenguang;
Zhao, Lu;
Huang, Shenghai;
Zhang, Sen;
Jiang, Tao

Publication type:

Article

Phosphorylation of TET2 by AMPK is indispensable in myogenic differentiation.

Published in:

Epigenetics & Chromatin, 2019, v. 12, n. 1, p. N.PAG, doi. 10.1186/s13072-019-0281-x

By:

Zhang, Ting;
Guan, Xiaowen;
Choi, Un Lam;
Dong, Qiang;
Lam, Melody M. T.;
Zeng, Jianming;
Xiong, Jun;
Wang, Xianju;
Poon, Terence C. W.;
Zhang, Hongjie;
Zhang, Xuanjun;
Wang, Hailin;
Xie, Ruiyu;
Zhu, Bing;
Li, Gang

Publication type:

Article

Genome-wide analysis reveals a role for TDG in estrogen receptor-mediated enhancer RNA transcription and 3-dimensional reorganization.

Published in:

Epigenetics & Chromatin, 2018, v. 11, p. 1, doi. 10.1186/s13072-018-0176-2

By:

Kolendowski, Bart;
Hassan, Haider;
Krstic, Milica;
Isovic, Majdina;
Thillainadesan, Gobi;
Chambers, Ann F.;
Tuck, Alan B.;
Torchia, Joseph

Publication type:

Article

Dynamics of 5-methylcytosine and 5-hydroxymethylcytosine during pronuclear development in equine zygotes produced by ICSI.

Published in:

Epigenetics & Chromatin, 2017, v. 10, p. 1, doi. 10.1186/s13072-017-0120-x

By:

Heras, Sonia;
Smits, Katrien;
De Schauwer, Catharina;
Van Soom, Ann

Publication type:

Article

Differential DNA methylation at conserved non-genic elements and evidence for transgenerational inheritance following developmental exposure to mono(2-ethylhexyl) phthalate and 5-azacytidine in zebrafish.

Published in:

Epigenetics & Chromatin, 2017, v. 10, p. 1, doi. 10.1186/s13072-017-0126-4

By:

Kamstra, Jorke H.;
Sales, Liana Bastos;
Aleström, Peter;
Legler, Juliette

Publication type:

Article

Genome-wide methylation analysis demonstrates that 5-aza-2-deoxycytidine treatment does not cause random DNA demethylation in fragile X syndrome cells.

Published in:

Epigenetics & Chromatin, 2016, v. 9, p. 1, doi. 10.1186/s13072-016-0060-x

By:

Tabolacci, Elisabetta;
Mancano, Giorgia;
Lanni, Stella;
Palumbo, Federica;
Goracci, Martina;
Ferrè, Fabrizio;
Helmer-Citterich, Manuela;
Neri, Giovanni

Publication type:

Article

DNA demethylation by 5-aza-2'-deoxycytidine is imprinted, targeted to euchromatin, and has limited transcriptional consequences.

Published in:

Epigenetics & Chromatin, 2015, v. 8, n. 1, p. 1, doi. 10.1186/s13072-015-0004-x

By:

Ramos, María-Paz;
Neil Ari Wijetunga;
McLellan, Andrew S.;
Masako Suzuki;
Greally, John M.

Publication type:

Article

A permissive chromatin structure is adopted prior to site-specific DNA demethylation of developmentally expressed genes involved in macronuclear differentiation.

Published in:

Epigenetics & Chromatin, 2013, v. 6, n. 1, p. 1, doi. 10.1186/1756-8935-6-5

By:

Bulic, Aneta;
Postberg, Jan;
Fischer, Andreas;
Jönsson, Franziska;
Reuter, Günter;
Lipps, Hans J.

Publication type:

Article