Works matching DE "DNA alkylation"

Results: 123

Photo-Cross-Linking Probes for Trapping G-Quadruplex DNA.

Published in:

Angewandte Chemie, 2014, v. 126, n. 4, p. 1012, doi. 10.1002/ange.201307413

By:

Verga, Daniela;
Hamon, Florian;
Poyer, Florent;
Bombard, Sophie;
Teulade ‐ Fichou, Marie ‐ Paule

Publication type:

Article

Size- and Stereochemistry-Dependent Transcriptional Bypass of DNA Alkyl Phosphotriester Adducts in Mammalian Cells.

Published in:

DNA (2673-8856), 2022, v. 2, n. 4, p. 221, doi. 10.3390/dna2040016

By:

Tan, Ying;
Wu, Jiabin;
Clabaugh, Garrit;
Li, Lin;
Du, Hua;
Wang, Yinsheng

Publication type:

Article

Synthesis and in vitro anticancer evaluation of 1,8-naphthalimide N(4) and S(4)-derivatives combining DNA intercalation and alkylation capabilities.

Published in:

Research on Chemical Intermediates, 2016, v. 42, n. 3, p. 1741, doi. 10.1007/s11164-015-2115-1

By:

Brider, Tamara;
Redko, Boris;
Oron-Herman, Mor;
Cohen-Matzlich, Adi;
Gerlitz, Gabriel;
Gellerman, Gary;
Grynszpan, Flavio

Publication type:

Article

In silico profiling and structural insights of zinc metal ion on O6-methylguanine methyl transferase and its interactions using molecular dynamics approach.

Published in:

Journal of Molecular Modeling, 2021, v. 27, n. 2, p. 1, doi. 10.1007/s00894-020-04631-x

By:

Gharouni, Marzieh;
Mosaddeghi, Hamid;
Mehrzad, Jamshid;
Es-haghi, Ali;
Motavalizadehkakhky, Alireza

Publication type:

Article

Structure analysis of FAAP24 reveals single-stranded DNA-binding activity and domain functions in DNA damage response.

Published in:

Cell Research, 2013, v. 23, n. 10, p. 1215, doi. 10.1038/cr.2013.124

By:

Wang, Yucai;
Han, Xiao;
Wu, Fangming;
Leung, Justin W;
Lowery, Megan G;
Do, Huong;
Chen, Junjie;
Shi, Chaowei;
Tian, Changlin;
Li, Lei;
Gong, Weimin

Publication type:

Article

Post progression survival in glioblastoma: where are we?

Published in:

Journal of Neuro-Oncology, 2015, v. 121, n. 2, p. 399, doi. 10.1007/s11060-014-1651-7

By:

Franceschi, Enrico;
Ermani, Mario;
Bartolini, Stefania;
Bartolotti, Marco;
Poggi, Rosalba;
Tallini, Giovanni;
Marucci, Gianluca;
Fioravanti, Antonio;
Tosoni, Alicia;
Agati, Raffaele;
Bacci, Antonella;
Pozzati, Eugenio;
Morandi, Luca;
Balestrini, Damiano;
Ghimenton, Claudio;
Crisi, Girolamo;
Brandes, Alba

Publication type:

Article

Insight Into Factors Governing Formation, Synthesis and Stereochemical Configuration of DNA Adducts Formed by Mitomycins.

Published in:

Chemical Record, 2023, v. 23, n. 1, p. 1, doi. 10.1002/tcr.202200193

By:

Paz, Manuel M.;
Champeil, Elise

Publication type:

Article

Insight on the Interaction between the Camptothecin Derivative and DNA Oligomer Mimicking the Target of Topo I Inhibitors.

Published in:

Molecules, 2022, v. 27, n. 20, p. 6946, doi. 10.3390/molecules27206946

By:

Bocian, Wojciech;
Naumczuk, Beata;
Urbanowicz, Magdalena;
Sitkowski, Jerzy;
Bednarek, Elżbieta;
Wiktorska, Katarzyna;
Pogorzelska, Anna;
Wielgus, Ewelina;
Kozerski, Lech

Publication type:

Article

Isolation and Cytotoxic Activity of Phyllocladanes from the Roots of Acacia schaffneri (Leguminosae).

Published in:

Molecules, 2020, v. 25, n. 17, p. 3944, doi. 10.3390/molecules25173944

By:

Manríquez-Torres, José de Jesús;
Hernández-Lepe, Marco Antonio;
Chávez-Méndez, José Román;
González-Reyes, Susana;
Serafín-Higuera, Idanya Rubí;
Rodríguez-Uribe, Genaro;
Torres-Valencia, Jesús Martín;
Zoumpoulakis, Panagiotis;
Tesoriere, Luisa

Publication type:

Article

A Single-Turnover Kinetic Study of DNA Demethylation Catalyzed by Fe(II)/α-Ketoglutarate-Dependent Dioxygenase AlkB.

Published in:

Molecules, 2019, v. 24, n. 24, p. 4576, doi. 10.3390/molecules24244576

By:

Kanazhevskaya, Lyubov Yu.;
Alekseeva, Irina V.;
Fedorova, Olga S.;
Sousa, Sérgio F.

Publication type:

Article

Synthetic Routes to N-9 Alkylated 8-Oxoguanines; Weak Inhibitors of the Human DNA Glycosylase OGG1.

Published in:

Molecules, 2015, v. 20, n. 9, p. 15944, doi. 10.3390/molecules200915944

By:

Mahajan, Tushar R.;
Ytre-Arne, Mari Eknes;
Strøm-Andersen, Pernille;
Dalhus, Bjørn;
Gundersen, Lise-Lotte

Publication type:

Article

Synthesis and Cytotoxicity Evaluation of Naphthalimide Derived N-Mustards.

Published in:

Molecules, 2014, v. 19, n. 7, p. 8803, doi. 10.3390/molecules19078803

By:

Qinghua Lou;
Liyan Ji;
Wenhe Zhong;
Shasha Li;
Siwang Yu;
Zhongjun Li;
Xiangbao Meng

Publication type:

Article

Immunological and mass spectrometry-based approaches to determine thresholds of the mutagenic DNA adduct O<sup>6</sup>-methylguanine in vivo.

Published in:

Archives of Toxicology, 2019, v. 93, n. 2, p. 559, doi. 10.1007/s00204-018-2355-0

By:

Kraus, Alexander;
McKeague, Maureen;
Seiwert, Nina;
Nagel, Georg;
Geisen, Susanne M.;
Ziegler, Nathalie;
Trantakis, Ioannis A.;
Kaina, Bernd;
Thomas, Adam D.;
Sturla, Shana J.;
Fahrer, Jörg

Publication type:

Article

An evidence-based review of the genotoxic and reproductive effects of sulfur mustard.

Published in:

Archives of Toxicology, 2017, v. 91, n. 3, p. 1143, doi. 10.1007/s00204-016-1911-8

By:

Khan, Fazlullah;
Niaz, Kamal;
Ismail Hassan, Fatima;
Abdollahi, Mohammad

Publication type:

Article

Alkylation of 1,3-benzothiazin-4-one 2-oxo-, 2-arylimino-, and 2-thioxo derivatives.

Published in:

Chemistry of Heterocyclic Compounds, 2015, v. 51, n. 4, p. 370, doi. 10.1007/s10593-015-1709-2

By:

Shestakov, Alexandr;
Prezent, Mikhail;
Zlatoustovskaya, Evgenia;
Shikhaliev, Khidmet;
Falaleev, Alexandr;
Sidorenko, Oleg

Publication type:

Article

Alkylation of imidazole and benzimidazole derivatives with 1-(iodomethyl)-1,1,3,3,3-pentamethyldisiloxane - a new method for the preparation of organocyclosiloxane iodides.

Published in:

Chemistry of Heterocyclic Compounds, 2015, v. 51, n. 4, p. 381, doi. 10.1007/s10593-015-1711-8

By:

Zhilitskaya, Larisa;
Yarosh, Nina;
Shagun, Ludmila;
Dorofeev, Ivan;
Larina, Ludmila

Publication type:

Article

ROLE OF DNA REPAIR IN AGING AND MALIGNANCY.

Published in:

Era's Journal of Medical Research, 2021, v. 8, n. 2, p. 194, doi. 10.24041/ejmr2021.36

By:

Fatima, Kaynat;
Raza, Syed Tasleem;
Rizvi, Saliha;
Srivastava, Sanchita

Publication type:

Article

Generation of reconstituted hemato-lymphoid murine embryos by placental transplantation into embryos lacking HSCs.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-83652-9

By:

Jeon, Hyojung;
Asano, Keigo;
Wakimoto, Arata;
Kulathunga, Kaushalya;
Tran, Mai Thi Nhu;
Nakamura, Megumi;
Yokomizo, Tomomasa;
Hamada, Michito;
Takahashi, Satoru

Publication type:

Article

The histone deacetylase inhibitor SAHA sensitizes acute myeloid leukemia cells to a combination of nucleoside analogs and the DNA-alkylating agent busulfan.

Published in:

Leukemia & Lymphoma, 2014, v. 55, n. 7, p. 1625, doi. 10.3109/10428194.2013.856007

By:

Song, Guiyun;
Valdez, Benigno C.;
Li, Yang;
Dominguez, Jose R.;
Corn, Paul;
Champlin, Richard E.;
Andersson, Borje S.

Publication type:

Article

The SUMO stress response in transcriptional regulation: Causal relationships or secondary bystander effects?

Published in:: BioEssays, 2022, v. 44, n. 7, p. 1, doi. 10.1002/bies.202200065
Publication type:: Article

The Mechanism of Action of Cyclophosphamide and Its Consequences for the Development of a New Generation of Oxazaphosphorine Cytostatics.

Published in:

Scientia Pharmaceutica, 2020, v. 88, n. 4, p. 1, doi. 10.3390/scipharm88040042

By:

Voelcker, Georg

Publication type:

Article

Insight into the molecular initiating event of mutagenic N-nitrosamines: a computational study on DNA alkylation by their diazonium ions.

Published in:

Environmental Toxicology & Chemistry, 2025, v. 44, n. 3, p. 777, doi. 10.1093/etojnl/vgae088

By:

Cheng, Shiyang;
Qiu, Houjun;
Ding, Wen;
Kong, Chuiyuan;
Ma, Juchen;
Hou, Runze;
Liu, Chunsheng;
Ji, Li

Publication type:

Article

Synthesis of DOHNAA, a Mycobacterium tuberculosis Cholesterol CD Ring Catabolite and FadD3 Substrate.

Published in:

European Journal of Organic Chemistry, 2015, v. 2015, n. 27, p. 6075, doi. 10.1002/ejoc.201500698

By:

Stubbing, Louise A.;
Lott, J. Shaun;
Dawes, Stephanie S.;
Furkert, Daniel P.;
Brimble, Margaret A.

Publication type:

Article

Synthesis and DNA-Damaging Properties of Cisplatin-N-Mustard Conjugates.

Published in:

European Journal of Organic Chemistry, 2015, v. 2015, n. 12, p. 2654, doi. 10.1002/ejoc.201500144

By:

Schiesser, Stefan;
Hackner, Benjamin;
Vrabel, Milan;
Beck, Wolfgang;
Carell, Thomas

Publication type:

Article

2-[2-(Aziridin-1-yl)ethyl]-5,5-dimethyl-2,5-dihydro-4H-benzo [e]isoindol-4-one (Cytotoxic Oxonaphthalene-Pyrroles, Part IV).

Published in:

Molbank, 2012, v. 12, n. 4, p. 1, doi. 10.3390/M781

By:

Spreitzer, Helmut;
Puschmann, Christiane

Publication type:

Article

2-[3-(Aziridin-1-yl)-2-hydroxypropyl]-5,5-dimethyl-2,5-dihydro-4H-benzo[e]isoindol-4-one (Cytotoxic Oxonaphthalene-Pyrroles, Part III).

Published in:

Molbank, 2012, v. 12, n. 3, p. 1, doi. 10.3390/M772

By:

Spreitzer, Helmut;
Puschmann, Christiane

Publication type:

Article

In Memoriam: Maria Ciaramella (1958–2018).

Published in:

2019

By:

Perugino, Giuseppe;
Valenti, Anna;
Cobucci-Ponzano, Beatrice;
Moracci, Marco;
Rossi, Mosè

Publication type:

Announcement

Erratum to: A novel thermostable protein-tag: optimization of the Sulfolobus solfataricus DNA-alkyl-transferase by protein engineering.

Published in:

2016

By:

Vettone, Antonella;
Serpe, Mario;
Hidalgo, Aurelio;
Berenguer, José;
Monaco, Giovanni;
Valenti, Anna;
Rossi, Mosé;
Ciaramella, Maria;
Perugino, Giuseppe

Publication type:

Erratum

Archaeal DNA alkylation repair conducted by DNA glycosylase and methyltransferase.

Published in:

Applied Microbiology & Biotechnology, 2023, v. 107, n. 10, p. 3131, doi. 10.1007/s00253-023-12506-3

By:

Yin, Youcheng;
Zhang, Likui

Publication type:

Article

A systematic review on multipotent carcinogenic agent, N‐nitrosodiethylamine (NDEA), its major risk assessment, and precautions.

Published in:

Journal of Applied Toxicology, 2024, v. 44, n. 8, p. 1108, doi. 10.1002/jat.4574

By:

Janmeda, Pracheta;
Jain, Divya;
Chaudhary, Priya;
Meena, Mukesh;
Singh, Devendra

Publication type:

Article

Regulation of the DNA damage response by ubiquitin conjugation.

Published in:

Frontiers in Genetics, 2015, v. 6, p. 1, doi. 10.3389/fgene.2015.00098

By:

Brinkmann, Kerstin;
Schell, Michael;
Hoppe, Thorsten;
Kashkar, Hamid

Publication type:

Article

DDR-mediated crosstalk between DNA-damaged cells and their microenvironment.

Published in:

Frontiers in Genetics, 2015, v. 6, p. 1, doi. 10.3389/fgene.2015.00094

By:

Malaquin, Nicolas;
Carrier-Leclerc, Audrey;
Dessureault, Mireille;
Rodier, Francis

Publication type:

Article

para-Quinone Methide: a New Player in Asymmetric Catalysis.

Published in:

ChemCatChem, 2015, v. 7, n. 10, p. 1524, doi. 10.1002/cctc.201500176

By:

Parra, Alejandro;
Tortosa, Mariola

Publication type:

Article

Human and Arabidopsis alpha‐ketoglutarate‐dependent dioxygenase homolog proteins—New players in important regulatory processes.

Published in:

IUBMB Life, 2020, v. 72, n. 6, p. 1126, doi. 10.1002/iub.2276

By:

Marcinkowski, Michał;
Pilžys, Tomaš;
Garbicz, Damian;
Steciuk, Jaroslaw;
Zugaj, Dorota;
Mielecki, Damian;
Sarnowski, Tomasz J.;
Grzesiuk, Elżbieta

Publication type:

Article

Shiga Toxin 1, as DNA Repair Inhibitor, Synergistically Potentiates the Activity of the Anticancer Drug, Mafosfamide, on Raji Cells.

Published in:

Toxins, 2013, v. 5, n. 2, p. 431, doi. 10.3390/toxins5020431

By:

Brigotti, Maurizio;
Arfilli, Valentina;
Carnicelli, Domenica;
Rocchi, Laura;
Calcabrini, Cinzia;
Ricci, Francesca;
Pagliaro, Pasqualepaolo;
Tazzari, Pier Luigi;
Alfieri, Roberta R.;
Petronini, Pier Giorgio;
Sestili, Piero

Publication type:

Article

DNA Polymerases ImuC and DinB Are Involved in DNA Alkylation Damage Tolerance in Pseudomonas aeruginosa and Pseudomonas putida.

Published in:

PLoS ONE, 2017, v. 12, n. 1, p. 1, doi. 10.1371/journal.pone.0170719

By:

Jatsenko, Tatjana;
Sidorenko, Julia;
Saumaa, Signe;
Kivisaar, Maia

Publication type:

Article

Combined Gene Expression and RNAi Screening to Identify Alkylation Damage Survival Pathways from Fly to Human.

Published in:

PLoS ONE, 2016, v. 11, n. 4, p. 1, doi. 10.1371/journal.pone.0153970

By:

Zanotto-Filho, Alfeu;
Dashnamoorthy, Ravi;
Loranc, Eva;
de Souza, Luis H. T.;
Moreira, José C. F.;
Suresh, Uthra;
Chen, Yidong;
Bishop, Alexander J. R.

Publication type:

Article

Aryl sulfonate based anticancer alkylating agents.

Published in:

Pakistan Journal of Pharmaceutical Sciences, 2018, v. 31, p. 1081

By:

Sheikh, Hamdullah Khadim;
Arshad, Tanzila;
Kanwal, Ghazala

Publication type:

Article

The interplay mechanism between IDH mutation, MGMT-promoter methylation, and PRMT5 activity in the progression of grade 4 astrocytoma: unraveling the complex triad theory.

Published in:

Oncology Research, 2024, v. 32, n. 6, p. 1037, doi. 10.32604/or.2024.051112

By:

KURDI, MAHER;
ALKHOTANI, ALAA;
SABBAGH, ABDULRAHMAN;
FAIZO, EYAD;
LARY, AHMED;
BAMAGA, AHMED K.;
ALMANSOURI, MAJID;
ALSHARIF, BADR THAMER;
BAEESA, SALEH

Publication type:

Article

Covalent Chemical 5′-Functionalization of RNA with Diazo Reagents.

Published in:

Angewandte Chemie International Edition, 2016, v. 55, n. 35, p. 10283, doi. 10.1002/anie.201604385

By:

Gampe, Christian M.;
Hollis-Symynkywicz, Micah;
Zécri, Frédéric

Publication type:

Article

Photo-Cross-Linking Probes for Trapping G-Quadruplex DNA.

Published in:

Angewandte Chemie International Edition, 2014, v. 53, n. 4, p. 994, doi. 10.1002/anie.201307413

By:

Verga, Daniela;
Hamon, Florian;
Poyer, Florent;
Bombard, Sophie;
Teulade‐Fichou, Marie‐Paule

Publication type:

Article

In situ organic compound analysis on a meteorite surface by desorption electrospray ionization coupled with an Orbitrap mass spectrometer.

Published in:

Rapid Communications in Mass Spectrometry: RCM, 2018, v. 32, n. 12, p. 959, doi. 10.1002/rcm.8121

By:

Naraoka, Hiroshi;
Hashiguchi, Minako

Publication type:

Article

Synthesis of 2‐Chloro‐3‐amino indenone derivatives and their evaluation as inhibitors of DNA dealkylation repair.

Published in:

Chemical Biology & Drug Design, 2021, v. 97, n. 6, p. 1170, doi. 10.1111/cbdd.13839

By:

Nigam, Richa;
Raveendra Babu, Kaki;
Ghosh, Topi;
Kumari, Bhavini;
Das, Prolay;
Anindya, Roy;
Ahmed Khan, Faiz

Publication type:

Article

Involvement of Akt in mitomycin C and its analog triggered cytotoxicity in MCF‐7 and K562 cancer cells.

Published in:

Chemical Biology & Drug Design, 2018, v. 92, n. 6, p. 2022, doi. 10.1111/cbdd.13374

By:

Cheng, Shu‐Yuan;
Vargas, Anayatzinc;
Lee, Ji‐Young;
Clement, Cristina C.;
Champeil, Elise

Publication type:

Article

Preclinical bioavailability-bioequivalence and toxico-kinetic profile of stable succinc acid cocrystal of temozolomide.

Published in:

Current Science (00113891), 2015, v. 108, n. 6, p. 1097

By:

Sravani, Edula;
Mannava, M. K. Chaitanya;
Kaur, Damandeep;
Annapurna, B. R.;
Khan, Ronaq Ali;
Suresh, Kuthuru;
Mittapalli, Sudhir;
Nangia, Ashwini;
Kumar, B. Dinesh

Publication type:

Article

Synthesis of Various Water Soluble and Stable Copper Complexes Bearing N‐Heterocyclic Carbene Ligands and Their Activity in DNA Alkylation.

Published in:

Helvetica Chimica Acta, 2019, v. 102, n. 1, p. N.PAG, doi. 10.1002/hlca.201800183

By:

Geigle, Stefanie;
Rasale, Dnyaneshwar B.;
Gillingham, Dennis

Publication type:

Article

Hoogsteen Base Pairings: A New Paradigm for DNA Replication, DNA Recognition, and DNA Repair.

Published in:

Journal of Experimental & Molecular Biology, 2022, v. 23, n. 1, p. 78, doi. 10.47743/jemb-2022-72

By:

Datta, Neelabh

Publication type:

Article

The NuA4 Complex Promotes Translesion Synthesis (TLS)-Mediated DNA Damage Tolerance.

Published in:

Genetics, 2015, v. 199, n. 4, p. 1065, doi. 10.1534/genetics.115.174490

By:

Renaud-Young, Margaret;
Lloyd, David C.;
Chatfield-Reed, Kate;
George, Iain;
Chua, Gordon;
Cobb, Jennifer

Publication type:

Article

Meiotic interstrand DNA damage escapes paternal repair and causes chromosomal aberrations in the zygote by maternal misrepair.

Published in:

Scientific Reports, 2015, p. 7689, doi. 10.1038/srep07689

By:

Marchetti, Francesco;
Bishop, Jack;
Gingerich, John;
Wyrobek, Andrew J.

Publication type:

Article

Exposure of E. coli to DNA-Methylating Agents Impairs Biofilm Formation and Invasion of Eukaryotic Cells via Down Regulation of the N-Acetylneuraminate Lyase NanA.

Published in:

Frontiers in Microbiology, 2016, p. 85, doi. 10.3389/fmicb.2016.00147

By:

Di Pasquale, Pamela;
Di Somma, Angela;
Squillace, Marta;
Duilio, Angela;
Caterino, Marianna;
Rossi, Elio;
Landini, Paolo;
Iebba, Valerio;
Palamara, Annateresa;
Schippa, Serena;
Papa, Rosanna;
Selan, Laura;
Artini, Marco

Publication type:

Article