Works matching DE "DNA alkylation"

Results: 123

Post progression survival in glioblastoma: where are we?

Published in:

Journal of Neuro-Oncology, 2015, v. 121, n. 2, p. 399, doi. 10.1007/s11060-014-1651-7

By:

Franceschi, Enrico;
Ermani, Mario;
Bartolini, Stefania;
Bartolotti, Marco;
Poggi, Rosalba;
Tallini, Giovanni;
Marucci, Gianluca;
Fioravanti, Antonio;
Tosoni, Alicia;
Agati, Raffaele;
Bacci, Antonella;
Pozzati, Eugenio;
Morandi, Luca;
Balestrini, Damiano;
Ghimenton, Claudio;
Crisi, Girolamo;
Brandes, Alba

Publication type:

Article

Synthesis of Various Water Soluble and Stable Copper Complexes Bearing N‐Heterocyclic Carbene Ligands and Their Activity in DNA Alkylation.

Published in:

Helvetica Chimica Acta, 2019, v. 102, n. 1, p. N.PAG, doi. 10.1002/hlca.201800183

By:

Geigle, Stefanie;
Rasale, Dnyaneshwar B.;
Gillingham, Dennis

Publication type:

Article

RNA m6A involves in regulation of oxidative stress and apoptosis may via NF-kB pathway in cadmium-induced lung cells.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-024-02284-w

By:

Zhang, Nan;
Yang, Jie;
Zhao, Yuan;
Li, Wenhong;
Zhao, Bo;
Li, Rongxian;
He, Zuoshun;
Gu, Shiyan

Publication type:

Article

Per-2,3- O -alkylated β -cyclodextrin duplexes connected with disulfide bonds.

Published in:

Supramolecular Chemistry, 2017, v. 29, n. 1, p. 40, doi. 10.1080/10610278.2016.1164860

By:

Tatar, Ameneh;
Grishina, Anastasia;
Buděšínský, Miloš;
Kraus, Tomáš

Publication type:

Article

Assessing the effect of N-oxidation on the mutagenicity of 1-pyrazolines using the Ames assay.

Published in:

Toxicology Research, 2023, v. 12, n. 3, p. 503, doi. 10.1093/toxres/tfad036

By:

Inami, Keiko;
Miura, Motofumi;
Yoshida, Masafumi;
Mochizuki, Masataka

Publication type:

Article

Meiotic interstrand DNA damage escapes paternal repair and causes chromosomal aberrations in the zygote by maternal misrepair.

Published in:

Scientific Reports, 2015, p. 7689, doi. 10.1038/srep07689

By:

Marchetti, Francesco;
Bishop, Jack;
Gingerich, John;
Wyrobek, Andrew J.

Publication type:

Article

Adverse event profile of lomustine and temozolomide: a descriptive analysis from WHO-VigiAccess.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1534802

By:

Luo, Hua;
Fan, Shaohua;
Liang, Lu;
He, Youfu;
Chen, Jiangjie;
Xu, Chenghao;
Zhu, Jing;
Zhang, Liwei

Publication type:

Article

Study of the Physiological Alterations Induced by Cisplatin in Miceandthe Possible Protective Role of Green Tea.

Published in:

International Journal of Pharmacy & Life Sciences, 2018, v. 9, n. 2, p. 5722

By:

Mohamed, Idriss H.

Publication type:

Article

In situ organic compound analysis on a meteorite surface by desorption electrospray ionization coupled with an Orbitrap mass spectrometer.

Published in:

Rapid Communications in Mass Spectrometry: RCM, 2018, v. 32, n. 12, p. 959, doi. 10.1002/rcm.8121

By:

Naraoka, Hiroshi;
Hashiguchi, Minako

Publication type:

Article

Photoinduced DNA Interstrand Cross‐Linking by 1,1′‐Biphenyl Analogues: Substituents and Leaving Groups Combine to Determine the Efficiency of Cross‐Linker.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 16, p. 5215, doi. 10.1002/chem.202005064

By:

Fan, Heli;
Sun, Huabing;
Zhang, Qi;
Peng, Xiaohua

Publication type:

Article

Evaluation of the DNA Alkylation Properties of a Chlorambucil‐Conjugated Cyclic Pyrrole‐Imidazole Polyamide.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 8, p. 2782, doi. 10.1002/chem.202004421

By:

Hirose, Yuki;
Hashiya, Kaori;
Bando, Toshikazu;
Sugiyama, Hiroshi

Publication type:

Article

"Repaired and Activated" DNAzyme Enables the Monitoring of DNA Alkylation Repair in Live Cells.

Published in:

Angewandte Chemie, 2021, v. 133, n. 36, p. 20042, doi. 10.1002/ange.202106557

By:

Wang, Xiangnan;
Yi, Xin;
Huang, Zhimei;
He, Jianjun;
Wu, Zhenkun;
Chu, Xia;
Jiang, Jian‐Hui

Publication type:

Article

Nanopore Sequencing Accurately Identifies the Mutagenic DNA Lesion O6‐Carboxymethyl Guanine and Reveals Its Behavior in Replication.

Published in:

Angewandte Chemie, 2019, v. 131, n. 25, p. 8520, doi. 10.1002/ange.201902521

By:

Wang, Yu;
Patil, Kiran M.;
Yan, Shuanghong;
Zhang, Panke;
Guo, Weiming;
Wang, Yuqin;
Chen, Hong‐Yuan;
Gillingham, Dennis;
Huang, Shuo

Publication type:

Article

Insight Into Factors Governing Formation, Synthesis and Stereochemical Configuration of DNA Adducts Formed by Mitomycins.

Published in:

Chemical Record, 2023, v. 23, n. 1, p. 1, doi. 10.1002/tcr.202200193

By:

Paz, Manuel M.;
Champeil, Elise

Publication type:

Article

Erratum to: A novel thermostable protein-tag: optimization of the Sulfolobus solfataricus DNA-alkyl-transferase by protein engineering.

Published in:

2016

By:

Vettone, Antonella;
Serpe, Mario;
Hidalgo, Aurelio;
Berenguer, José;
Monaco, Giovanni;
Valenti, Anna;
Rossi, Mosé;
Ciaramella, Maria;
Perugino, Giuseppe

Publication type:

Erratum

Immunological and mass spectrometry-based approaches to determine thresholds of the mutagenic DNA adduct O6-methylguanine in vivo.

Published in:

Archives of Toxicology, 2019, v. 93, n. 2, p. 559, doi. 10.1007/s00204-018-2355-0

By:

Kraus, Alexander;
McKeague, Maureen;
Seiwert, Nina;
Nagel, Georg;
Geisen, Susanne M.;
Ziegler, Nathalie;
Trantakis, Ioannis A.;
Kaina, Bernd;
Thomas, Adam D.;
Sturla, Shana J.;
Fahrer, Jörg

Publication type:

Article

Size- and Stereochemistry-Dependent Transcriptional Bypass of DNA Alkyl Phosphotriester Adducts in Mammalian Cells.

Published in:

DNA (2673-8856), 2022, v. 2, n. 4, p. 221, doi. 10.3390/dna2040016

By:

Tan, Ying;
Wu, Jiabin;
Clabaugh, Garrit;
Li, Lin;
Du, Hua;
Wang, Yinsheng

Publication type:

Article

ROLE OF DNA REPAIR IN AGING AND MALIGNANCY.

Published in:

Era's Journal of Medical Research, 2021, v. 8, n. 2, p. 194, doi. 10.24041/ejmr2021.36

By:

Fatima, Kaynat;
Raza, Syed Tasleem;
Rizvi, Saliha;
Srivastava, Sanchita

Publication type:

Article

The SUMO stress response in transcriptional regulation: Causal relationships or secondary bystander effects?

Published in:: BioEssays, 2022, v. 44, n. 7, p. 1, doi. 10.1002/bies.202200065
Publication type:: Article

Developing a clinically relevant radiosensitizer for temozolomide-resistant gliomas.

Published in:

PLoS ONE, 2020, v. 15, n. 9, p. 1, doi. 10.1371/journal.pone.0238238

By:

Minea, Radu O.;
Duc, Tuan Cao;
Swenson, Stephen D.;
Cho, Hee-Yeon;
Huang, Mickey;
Hartman, Hannah;
Hofman, Florence M.;
Schönthal, Axel H.;
Chen, Thomas C.

Publication type:

Article

Aryl sulfonate based anticancer alkylating agents.

Published in:

Pakistan Journal of Pharmaceutical Sciences, 2018, v. 31, p. 1081

By:

Sheikh, Hamdullah Khadim;
Arshad, Tanzila;
Kanwal, Ghazala

Publication type:

Article

Sequence selectivity of azinomycin B in DNA alkylation and cross-linking: a QM/MM study.

Published in:

Journal of Molecular Modeling, 2013, v. 19, n. 1, p. 383, doi. 10.1007/s00894-012-1557-2

By:

Senthilnathan, Dhurairajan;
Kalaiselvan, Anbarasan;
Venuvanalingam, Ponnambalam

Publication type:

Article

Alkylation of 1,3-benzothiazin-4-one 2-oxo-, 2-arylimino-, and 2-thioxo derivatives.

Published in:

Chemistry of Heterocyclic Compounds, 2015, v. 51, n. 4, p. 370, doi. 10.1007/s10593-015-1709-2

By:

Shestakov, Alexandr;
Prezent, Mikhail;
Zlatoustovskaya, Evgenia;
Shikhaliev, Khidmet;
Falaleev, Alexandr;
Sidorenko, Oleg

Publication type:

Article

Alkylation of imidazole and benzimidazole derivatives with 1-(iodomethyl)-1,1,3,3,3-pentamethyldisiloxane - a new method for the preparation of organocyclosiloxane iodides.

Published in:

Chemistry of Heterocyclic Compounds, 2015, v. 51, n. 4, p. 381, doi. 10.1007/s10593-015-1711-8

By:

Zhilitskaya, Larisa;
Yarosh, Nina;
Shagun, Ludmila;
Dorofeev, Ivan;
Larina, Ludmila

Publication type:

Article

The Effect of Deuterium on Induction of the ada-Regulon with Alkylating Compounds in the Cells of Escherichia coli.

Published in:

Russian Journal of Genetics, 2018, v. 54, n. 8, p. 919, doi. 10.1134/S1022795418080124

By:

Smirnova, S. V.;
Abilev, S. K.;
Igonina, E. V.;
Glaser, V. M.;
Parmon, V. N.;
Yankovsky, N. K.

Publication type:

Article

Photo-induced DNA interstrand cross-links formed by a coumarin-modified nucleoside.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2019, v. 38, n. 3, p. 236, doi. 10.1080/15257770.2018.1515439

By:

Rozelle, Aaron Leland;
Kumar, Rayala Naveen;
Lee, Seongmin

Publication type:

Article

Effect of disulfide bonding and multimerization on proteoglycan 4’s cartilage boundary lubricating ability and adsorption.

Published in:

Connective Tissue Research, 2016, v. 57, n. 2, p. 113, doi. 10.3109/03008207.2015.1113271

By:

Abubacker, Saleem;
Ponjevic, Dragana;
Ham, Hyun O.;
Messersmith, Phillip B.;
Matyas, John R.;
Schmidt, Tannin A.

Publication type:

Article

Development and Application of a Slot-Blot Assay Using the Damage Sensing Protein Atl1 to Detect and Quantify O 6 -Alkylated Guanine Bases in DNA.

Published in:

Toxics, 2024, v. 12, n. 9, p. 649, doi. 10.3390/toxics12090649

By:

Yaakub, Hanum;
Howell, Anthony;
Margison, Geoffrey P.;
Povey, Andrew C.

Publication type:

Article

The histone deacetylase inhibitor SAHA sensitizes acute myeloid leukemia cells to a combination of nucleoside analogs and the DNA-alkylating agent busulfan.

Published in:

Leukemia & Lymphoma, 2014, v. 55, n. 7, p. 1625, doi. 10.3109/10428194.2013.856007

By:

Song, Guiyun;
Valdez, Benigno C.;
Li, Yang;
Dominguez, Jose R.;
Corn, Paul;
Champlin, Richard E.;
Andersson, Borje S.

Publication type:

Article

Human and Arabidopsis alpha‐ketoglutarate‐dependent dioxygenase homolog proteins—New players in important regulatory processes.

Published in:

IUBMB Life, 2020, v. 72, n. 6, p. 1126, doi. 10.1002/iub.2276

By:

Marcinkowski, Michał;
Pilžys, Tomaš;
Garbicz, Damian;
Steciuk, Jaroslaw;
Zugaj, Dorota;
Mielecki, Damian;
Sarnowski, Tomasz J.;
Grzesiuk, Elżbieta

Publication type:

Article

Regulation of the O6-methylguanine-DNA methyltransferase (MGMT) transcription by hormones.

Published in:

Biopolymers & Cell, 2015, v. 31, p. 8

By:

Z. M., Nidoieva;
A. P., Iatsyshyna;
L. L., Lukash

Publication type:

Article

DNA Polymerases ImuC and DinB Are Involved in DNA Alkylation Damage Tolerance in Pseudomonas aeruginosa and Pseudomonas putida.

Published in:

PLoS ONE, 2017, v. 12, n. 1, p. 1, doi. 10.1371/journal.pone.0170719

By:

Jatsenko, Tatjana;
Sidorenko, Julia;
Saumaa, Signe;
Kivisaar, Maia

Publication type:

Article

Combined Gene Expression and RNAi Screening to Identify Alkylation Damage Survival Pathways from Fly to Human.

Published in:

PLoS ONE, 2016, v. 11, n. 4, p. 1, doi. 10.1371/journal.pone.0153970

By:

Zanotto-Filho, Alfeu;
Dashnamoorthy, Ravi;
Loranc, Eva;
de Souza, Luis H. T.;
Moreira, José C. F.;
Suresh, Uthra;
Chen, Yidong;
Bishop, Alexander J. R.

Publication type:

Article

Screening of the chemoprotective effect of 13 compounds and their mixtures with sodium 2-mercaptoethanesulfonate against 2-chloroethyl ethyl sulfide.

Published in:

Journal of Applied Biomedicine, 2019, v. 17, n. 2, p. 136, doi. 10.32725/jab.2019.009

By:

Jost, Petr;
Pejchal, Jaroslav;
Kucera, Tomas;
Muckova, Lubica;
Stetina, Rudolf

Publication type:

Article

Accidental Encounter of Repair Intermediates in Alkylated DNA May Lead to Double-Strand Breaks in Resting Cells.

Published in:

2024

By:

Fujii, Shingo;
Fuchs, Robert P.

Publication type:

Editorial

DNA Alkylation Damage by Nitrosamines and Relevant DNA Repair Pathways.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 5, p. 4684, doi. 10.3390/ijms24054684

By:

Fahrer, Jörg;
Christmann, Markus

Publication type:

Article

DNA Demethylation in the Processes of Repair and Epigenetic Regulation Performed by 2-Ketoglutarate-Dependent DNA Dioxygenases.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 19, p. 10540, doi. 10.3390/ijms221910540

By:

Kuznetsov, Nikita A.;
Kanazhevskaya, Lyubov Yu.;
Fedorova, Olga S.

Publication type:

Article

Genomic Adaption and Mutational Patterns in a HaCaT Subline Resistant to Alkylating Agents and Ionizing Radiation.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 3, p. 1146, doi. 10.3390/ijms22031146

By:

Ullmann, Reinhard;
Becker, Benjamin Valentin;
Rothmiller, Simone;
Schmidt, Annette;
Thiermann, Horst;
Kaatsch, Hanns Leonhard;
Schrock, Gerrit;
Müller, Jessica;
Jakobi, Julia;
Obermair, Richard;
Port, Matthias;
Scherthan, Harry

Publication type:

Article

Characterization of the Proteins Involved in the DNA Repair Mechanism in M. smegmatis.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 15, p. 5391, doi. 10.3390/ijms21155391

By:

Di Somma, Angela;
Canè, Carolina;
Moretta, Antonio;
Cirillo, Arianna;
Cemič, Franz;
Duilio, Angela

Publication type:

Article

Every OGT Is Illuminated ... by Fluorescent and Synchrotron Lights.

Published in:

International Journal of Molecular Sciences, 2017, v. 18, n. 12, p. 2613, doi. 10.3390/ijms18122613

By:

Miggiano, Riccardo;
Valenti, Anna;
Rossi, Franca;
Rizzi, Menico;
Perugino, Giuseppe;
Ciaramella, Maria

Publication type:

Article

Reverse Gyrase Functions in Genome Integrity Maintenance by Protecting DNA Breaks In Vivo.

Published in:

International Journal of Molecular Sciences, 2017, v. 18, n. 7, p. 1340, doi. 10.3390/ijms18071340

By:

Wenyuan Han;
Xu Feng;
Qunxin She

Publication type:

Article

Protein Recognition in Drug-Induced DNA Alkylation: When the Moonlight Protein GAPDH Meets S23906-1/DNA Minor Groove Adducts.

Published in:

International Journal of Molecular Sciences, 2015, v. 16, n. 11, p. 26555, doi. 10.3390/ijms161125971

By:

Savreux-Lenglet, Gaëlle;
Depauw, Sabine;
David-Cordonnier, Marie-Hélène

Publication type:

Article

NMDA receptor signaling induces the chemoresistance of temozolomide via upregulation of MGMT expression in glioblastoma cells.

Published in:

Journal of Neuro-Oncology, 2022, v. 160, n. 2, p. 375, doi. 10.1007/s11060-022-04154-w

By:

Tsuji, Shohei;
Nakamura, Shinsuke;
Shoda, Kenji;
Yamada, Tetsuya;
Shimazawa, Masamitsu;
Nakayama, Noriyuki;
Iwama, Toru;
Hara, Hideaki

Publication type:

Article

Preliminary study of mechanism of action of SN38 derivatives. Physicochemical data, evidence of interaction and alkylation of DNA octamer d(GCGATCGC)2.

Published in:

Magnetic Resonance in Chemistry, 2017, v. 55, n. 2, p. 128, doi. 10.1002/mrc.4508

By:

Naumczuk, Beata;
Kawęcki, Robert;
Bocian, Wojciech;
Bednarek, Elżbieta;
Sitkowski, Jerzy;
Kozerski, Lech

Publication type:

Article

Transcriptional outcome of telomere signalling.

Published in:

Nature Reviews Genetics, 2014, v. 15, n. 7, p. 491, doi. 10.1038/nrg3743

By:

Ye, Jing;
Renault, Valérie M.;
Jamet, Karine;
Gilson, Eric

Publication type:

Article

A novel Porphyromonas gingivalis enzyme: An atypical dipeptidyl peptidase III with an ARM repeat domain.

Published in:

PLoS ONE, 2017, v. 12, n. 11, p. 1, doi. 10.1371/journal.pone.0188915

By:

Hromić-Jahjefendić, Altijana;
Jajčanin Jozić, Nina;
Kazazić, Saša;
Grabar Branilović, Marina;
Karačić, Zrinka;
Schrittwieser, Jörg H.;
Das, Krishna Mohan Padmanabha;
Tomin, Marko;
Oberer, Monika;
Gruber, Karl;
Abramić, Marija;
Tomić, Sanja

Publication type:

Article

Insight into the molecular initiating event of mutagenic N-nitrosamines: a computational study on DNA alkylation by their diazonium ions.

Published in:

Environmental Toxicology & Chemistry, 2025, v. 44, n. 3, p. 777, doi. 10.1093/etojnl/vgae088

By:

Cheng, Shiyang;
Qiu, Houjun;
Ding, Wen;
Kong, Chuiyuan;
Ma, Juchen;
Hou, Runze;
Liu, Chunsheng;
Ji, Li

Publication type:

Article

Synthesis of DOHNAA, a Mycobacterium tuberculosis Cholesterol CD Ring Catabolite and FadD3 Substrate.

Published in:

European Journal of Organic Chemistry, 2015, v. 2015, n. 27, p. 6075, doi. 10.1002/ejoc.201500698

By:

Stubbing, Louise A.;
Lott, J. Shaun;
Dawes, Stephanie S.;
Furkert, Daniel P.;
Brimble, Margaret A.

Publication type:

Article

Synthesis and DNA-Damaging Properties of Cisplatin-N-Mustard Conjugates.

Published in:

European Journal of Organic Chemistry, 2015, v. 2015, n. 12, p. 2654, doi. 10.1002/ejoc.201500144

By:

Schiesser, Stefan;
Hackner, Benjamin;
Vrabel, Milan;
Beck, Wolfgang;
Carell, Thomas

Publication type:

Article

2-[2-(Aziridin-1-yl)ethyl]-5,5-dimethyl-2,5-dihydro-4H-benzo [e]isoindol-4-one (Cytotoxic Oxonaphthalene-Pyrroles, Part IV).

Published in:

Molbank, 2012, v. 12, n. 4, p. 1, doi. 10.3390/M781

By:

Spreitzer, Helmut;
Puschmann, Christiane

Publication type:

Article