Works about DIHYDROPYRIMIDINE dehydrogenase

Results: 319

Detection of complete Dihydropyrimidine Dehydrogenase deficiency in a Tunisian family using a simple phenotypic test.

Published in:

2013

By:

Mani, Arij;
Nouira, Manel;
Ahmed, Slim Ben;
Saguem, Saad

Publication type:

Letter

Effective and economical column-based method for RNA isolation from animal cells.

Published in:

Biotechnology Letters, 2019, v. 41, n. 8/9, p. 915, doi. 10.1007/s10529-019-02700-7

By:

Niu, Qiaoge;
Cao, Maosheng;
Chen, Shuxiong;
Zhao, Yun;
Chen, Lu;
Li, Chunjin;
Zhou, Xu

Publication type:

Article

Evaluation of the Hepatoprotective Effect of L-Ascorbate 1-(2-Hydroxyethyl)-4,6-Dimethyl-1,2-Dihydropyrimidine-2-One Upon Exposure to Carbon Tetrachloride.

Published in:

Bulletin of Experimental Biology & Medicine, 2017, v. 162, n. 3, p. 340, doi. 10.1007/s10517-017-3610-8

By:

Vyshtakalyuk, A.;
Nazarov, N.;
Zobov, V.;
Abdulkhakov, S.;
Minnekhanova, O.;
Semenov, V.;
Galyametdinova, I.;
Cherepnev, G.;
Reznik, V.

Publication type:

Article

Selective inhibitory action of Biginelli-type dihydropyrimidines on depolarization-induced arterial smooth muscle contraction.

Published in:

Journal of Pharmacy & Pharmacology, 2012, v. 64, n. 5, p. 735, doi. 10.1111/j.2042-7158.2012.01466.x

By:

Cernecka, Hana;
Veizerova, Lucia;
Mensikova, Lucia;
Svetlik, Jan;
Krenek, Peter

Publication type:

Article

Frequency of dihydropyrimidine dehydrogenase and UDP-glucuronosyltransferase 1A1 variants in cancer patients requiring chemotherapy: A single-center study in southern India.

Published in:

Journal of Clinical & Basic Research, 2023, v. 7, n. 1, p. 6, doi. 10.61186/jcbr.7.1.6

By:

Gangavarapu, Kevin;
Bora, Nandini Shyamali;
Srinivas, Maddali;
Hasan, Qurratulain

Publication type:

Article

Pyrimidine Biosynthesis and Ribonucleoside Metabolism in Species of Pseudomonas.

Published in:

Fermentation (Basel), 2023, v. 9, n. 11, p. 955, doi. 10.3390/fermentation9110955

By:

West, Thomas P.

Publication type:

Article

Carmofur prevents cell cycle progression by reducing E2F8 transcription in temozolomide-resistant glioblastoma cells.

Published in:

Cell Death Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41420-023-01738-x

By:

Hawkins, Cyntanna C.;
Jones, Amber B.;
Gordon, Emily R.;
Harsh, Yuvika;
Ziebro, Julia K.;
Willey, Christopher D.;
Griguer, Corinne;
Crossman, David K.;
Cooper, Sara J.;
Ramanadham, Sasanka;
Doan, Ninh;
Hjelmeland, Anita B.

Publication type:

Article

Colon Cancer Pharmacogenetics: A Narrative Review.

Published in:

Pharmacy, 2022, v. 10, n. 4, p. 95, doi. 10.3390/pharmacy10040095

By:

Alfaro Alfaro, Álvaro Esteban;
Murillo Castillo, Brayan;
Cordero García, Eugenia;
Tascón, Javier;
Morales, Ana I.

Publication type:

Article

Germline cis variant determines epigenetic regulation of the anti-cancer drug metabolism gene dihydropyrimidine dehydrogenase (DPYD).

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.94075

By:

Ting Zhang;
Ambrodji, Alisa;
Huixing Huang;
Bouchonville, Kelly J.;
Etheridge, Amy S.;
Schmidt, Remington E.;
Bembenek, Brianna M.;
Temesgen, Zoey B.;
Zhiquan Wang;
Innocenti, Federico;
Stroka, Deborah;
Diasio, Robert B.;
Largiadèr, Carlo R.;
Offer, Steven M.

Publication type:

Article

Exploring the impact of MiR-92a-3p on FOLFOX chemoresistance biomarker genes in colon cancer cell lines.

Published in:

Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1376638

By:

Escalante, Paula I.;
Quiñones, Luis A.;
Contreras, Héctor R.

Publication type:

Article

Implementing pharmacogenetic testing in fluoropyrimidine-treated cancer patients: DPYD genotyping to guide chemotherapy dosing in Greece.

Published in:

Frontiers in Pharmacology, 2023, p. 01, doi. 10.3389/fphar.2023.1248898

By:

Ragia, Georgia;
Maslarinou, Anthi;
Atzemian, Natalia;
Biziota, Eirini;
Koukaki, Triantafyllia;
Ioannou, Charalampia;
Balgkouranidou, Ioanna;
Kolios, George;
Kakolyris, Stylianos;
Xenidis, Nikolaos;
Amarantidis, Kyriakos;
Manolopoulos, Vangelis G.

Publication type:

Article

Implementation of pharmacogenetic testing in oncology: DPYD-guided dosing to prevent fluoropyrimidine toxicity in British Columbia.

Published in:

Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1257745

By:

Wu, Angela;
Anderson, Helen;
Hughesman, Curtis;
Young, Sean;
Lohrisch, Caroline;
Ross, Colin J. D.;
Carleton, Bruce C.

Publication type:

Article

Pharmacogenomic-guided dosing of fluoropyrimidines beyond DPYD: time for a polygenic algorithm?

Published in:

Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1184523

By:

Maslarinou, Anthi;
Manolopoulos, Vangelis G.;
Ragia, Georgia

Publication type:

Article

Identification of dihydropyrimidine dehydrogenase as a virulence factor essential for the survival of Entamoeba histolytica in glucose-poor environments.

Published in:

Cellular Microbiology, 2013, v. 15, n. 1, p. 130, doi. 10.1111/cmi.12036

By:

Baumel‐Alterzon, Sharon;
Weber, Christian;
Guillén, Nancy;
Ankri, Serge

Publication type:

Article

Osteogenesis Imperfecta, Pseudoachalasia, and Gastric Cancer.

Published in:

Case Reports in Gastrointestinal Medicine, 2015, v. 2015, p. 1, doi. 10.1155/2015/685459

By:

Mizrak, Dilsa;
Alkan, Ali;
Erdogdu, Batuhan;
Utkan, Gungor

Publication type:

Article

Identifying a Novel DPYD Polymorphism Associated with Severe Toxicity to 5-FU Chemotherapy in a Saudi Patient.

Published in:

Case Reports in Genetics, 2019, p. 1, doi. 10.1155/2019/5150725

By:

Bukhari, Nedal;
Azam, Faisal;
Alfawaz, Mohammed;
Zahrani, Mohammed

Publication type:

Article

The beneficial influence of rhubarb on 5-fluorouracil-induced ileal mucositis and the combined role of aquaporin-4, tumour necrosis factor-α, nuclear factor-kappa B & matrix metalloproteinase-9 in rat model: histological study.

Published in:

Anatomy & Cell Biology, 2020, v. 53, n. 2, p. 228, doi. 10.5115/acb.20.014

By:

Kamar, Samaa Samir;
Baky, Mostafa Hasan;
Omar, Abeer Ibraheem

Publication type:

Article

Single virus fingerprinting by widefield interferometric defocus-enhanced mid-infrared photothermal microscopy.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-42439-4

By:

Xia, Qing;
Guo, Zhongyue;
Zong, Haonan;
Seitz, Scott;
Yurdakul, Celalettin;
Ünlü, M. Selim;
Wang, Le;
Connor, John H.;
Cheng, Ji-Xin

Publication type:

Article

Metabolic engineering of a fast-growing cyanobacterium Synechococcus elongatus PCC 11801 for photoautotrophic production of succinic acid.

Published in:

Biotechnology for Biofuels, 2020, v. 13, n. 1, p. 1, doi. 10.1186/s13068-020-01727-7

By:

Sengupta, Shinjinee;
Jaiswal, Damini;
Sengupta, Annesha;
Shah, Shikha;
Gadagkar, Shruti;
Wangikar, Pramod P.

Publication type:

Article

RNA structural probing of guanine and uracil nucleotides in yeast.

Published in:

PLoS ONE, 2023, v. 18, n. 7, p. 1, doi. 10.1371/journal.pone.0288070

By:

Xiao, Kevin;
Ghalei, Homa;
Khoshnevis, Sohail

Publication type:

Article

Study the adsorption process of 5-Fluorouracil drug on the pristine and doped graphdiyne nanosheet.

Published in:

Journal of Molecular Modeling, 2021, v. 27, n. 2, p. 1, doi. 10.1007/s00894-020-04629-5

By:

Yuan, Jingjing;
Mohamadi, Ali

Publication type:

Article

Response to Letter: Cost Implications of Reactive Versus Prospective Testing for Dihydropyrimidine Dehydrogenase Deficiency in Patients With Colorectal Cancer: A Single-Institution Experience.

Published in:

2019

By:

O'Farrell, Eoin;
Bird, Brian;
Murphy, Con

Publication type:

Letter

Cost Implications of Reactive Versus Prospective Testing for Dihydropyrimidine Dehydrogenase Deficiency in Patients With Colorectal Cancer: A Single-Institution Experience.

Published in:

Dose-Response, 2018, v. 16, n. 4, p. 1, doi. 10.1177/1559325818803042

By:

Murphy, Con;
Byrne, Stephen;
Ahmed, Gul;
Kenny, Andrew;
Gallagher, James;
Harvey, Harry;
O'Farrell, Eoin;
Bird, Brian

Publication type:

Article

Comparative Analysis of Transcriptome Responses to Cold Stress in Galeruca daurica (Coleoptera: Chrysomelidae).

Published in:

Journal of Insect Science, 2019, v. 19, n. 6, p. N.PAG, doi. 10.1093/jisesa/iez109

By:

Zhou, Xiao-Rong;
Shan, Yan-Min;
Tan, Yao;
Zhang, Zhuo-Ran;
Pang, Bao-Ping

Publication type:

Article

Relationship Between the DPD and TS mRNA Expression and the Response to S-1-Based Chemotherapy and Prognosis in Patients with Advanced Gastric Cancer.

Published in:

Cell Biochemistry & Biophysics, 2015, v. 71, n. 3, p. 1653, doi. 10.1007/s12013-014-0387-5

By:

Shen, Xiao-Ming;
Zhou, Chong;
Lian, Lian;
Li, Li-Qun;
Li, Wei;
Tao, Min

Publication type:

Article

The Prognostic and Predictive Value of Dihydropyrimidine Dehydrogenase-Related Indicators in Clinical Outcomes of Chemotherapy in Colorectal Cancer Patients: a Systematic Review and Meta-Analysis.

Published in:

Pathology & Oncology Research, 2020, v. 26, n. 1, p. 121, doi. 10.1007/s12253-018-00563-3

By:

Sun, Xiaojun;
Guo, Shilei

Publication type:

Article

Thymine-Modified Nanocarrier for Doxorubicin Delivery in Glioblastoma Cells.

Published in:

Molecules, 2023, v. 28, n. 2, p. 551, doi. 10.3390/molecules28020551

By:

Ziganshina, Albina Y.;
Mansurova, Elina E.;
Voloshina, Alexandra D.;
Lyubina, Anna P.;
Amerhanova, Syumbelya K.;
Shulaeva, Marina M.;
Nizameev, Irek R.;
Kadirov, Marsil K.;
Bakhtiozina, Leysan R.;
Semenov, Vyacheslav E.;
Antipin, Igor S.

Publication type:

Article

Interaction of Thymine DNA Glycosylase with Oxidised 5-Methyl-cytosines in Their Amino- and Imino-Forms.

Published in:

Molecules, 2021, v. 26, n. 19, p. 5728, doi. 10.3390/molecules26195728

By:

Volkenandt, Senta;
Beierlein, Frank;
Imhof, Petra

Publication type:

Article

Structural Insights of Three 2,4-Disubstituted Dihydropyrimidine-5-carbonitriles as Potential Dihydrofolate Reductase Inhibitors.

Published in:

Molecules, 2021, v. 26, n. 11, p. 3286, doi. 10.3390/molecules26113286

By:

Al-Wahaibi, Lamya H.;
Shaik, Althaf;
Elmorsy, Mohammed A.;
Abdelbaky, Mohammed S. M.;
Garcia-Granda, Santiago;
Thamotharan, Subbiah;
Thiruvenkatam, Vijay;
El-Emam, Ali A.

Publication type:

Article

Force Field Parameters for Fe 2+ 4 S 2− 4 Clusters of Dihydropyrimidine Dehydrogenase, the 5-Fluorouracil Cancer Drug Deactivation Protein: A Step towards In Silico Pharmacogenomics Studies.

Published in:

Molecules, 2021, v. 26, n. 10, p. 2929, doi. 10.3390/molecules26102929

By:

Tendwa, Maureen Bilinga;
Chebon-Bore, Lorna;
Lobb, Kevin;
Musyoka, Thommas Mutemi;
Tastan Bishop, Özlem;
Caballero, Julio

Publication type:

Article

Prebiotic Route to Thymine from Formamide—A Combined Experimental–Theoretical Study.

Published in:

Molecules, 2021, v. 26, n. 8, p. 2248, doi. 10.3390/molecules26082248

By:

Petera, Lukáš;
Mrazikova, Klaudia;
Nejdl, Lukas;
Zemankova, Kristyna;
Vaculovicova, Marketa;
Pastorek, Adam;
Civis, Svatopluk;
Kubelik, Petr;
Heays, Alan;
Cassone, Giuseppe;
Sponer, Jiri;
Ferus, Martin;
Sponer, Judit

Publication type:

Article

Nonadiabatic Absorption Spectra and Ultrafast Dynamics of DNA and RNA Photoexcited Nucleobases.

Published in:

Molecules, 2021, v. 26, n. 6, p. 1743, doi. 10.3390/molecules26061743

By:

Green, James A.;
Jouybari, Martha Yaghoubi;
Aranda, Daniel;
Improta, Roberto;
Santoro, Fabrizio;
Gauld, James

Publication type:

Article

Chemosensitization of HT29 and HT29-5FU Cell Lines by a Combination of a Multi-Tyrosine Kinase Inhibitor and 5FU Downregulates ABCC1 and Inhibits PIK3CA in Light of Their Importance in Saudi Colorectal Cancer.

Published in:

Molecules, 2021, v. 26, n. 2, p. 334, doi. 10.3390/molecules26020334

By:

Abdalla, Ashraf N.;
Malki, Waleed H.;
Qattan, Amal;
Shahid, Imran;
Hossain, Mohammad Akbar;
Ahmed, Muhammad;
Bortolozzi, Roberta

Publication type:

Article

Alkylation of Tetrahydropyrimidine-2-thiones with Ethyl Chloroacetate.

Published in:

Chemistry of Heterocyclic Compounds, 2014, v. 49, n. 11, p. 1681, doi. 10.1007/s10593-014-1420-8

By:

Shiryaev, A.;
Kolesnikova, N.;
Kuznetsova, N.;
Lashmanova, E.

Publication type:

Article

Reaction of 6-methyl-2-(2-oxo-2-phenyl-ethylidene)-2,3-dihydropyrimidin-4(1 H)-one with hydrazine and hydroxylamine.

Published in:

Chemistry of Heterocyclic Compounds, 2013, v. 48, n. 10, p. 1487, doi. 10.1007/s10593-013-1162-z

By:

Yavolovskii, A.;
Grishchuk, L.;
Rakipov, I.;
Stepanov, D.;
Ivanov, Yu.;
Kamalov, G.

Publication type:

Article

干预自噬影响DPD的表达促进5-FU抗结直肠癌疗效的实验研究.

Published in:

China Oncology, 2022, v. 32, n. 12, p. 1199, doi. 10.19401/j.cnki.1007-3639.2022.12.008

By:

崔忠泽;
何双;
温菲菲;
李扬扬;
许晓阳;
路丽祯;
吴淑华

Publication type:

Article

Topical drug delivery of 5-fluorouracil proniosomal gel for the treatment of skin cancer: in vitro and in vivo evaluation.

Published in:

Pharmaceutical Sciences Asia, 2021, v. 48, n. 2, p. 147, doi. 10.29090/psa.2021.02.20.002

By:

Rajkumar, Jampala;
Radha, Gadela Venkata

Publication type:

Article

A trans-ethnic genetic study of rheumatoid arthritis identified FCGR2A as a candidate common risk factor in Japanese and European populations.

Published in:

Modern Rheumatology, 2012, v. 22, n. 1, p. 52, doi. 10.3109/s10165-011-0467-y

By:

Meziani, Roubila;
Yamada, Ryo;
Takahashi, Meiko;
Ohigashi, Kenei;
Morinobu, Akio;
Terao, Chikashi;
Hiratani, Hitomi;
Ohmura, Koichiro;
Yamaguchi, Masao;
Nomura, Takashi;
Vasilescu, Alexandre;
Kokubo, Miki;
Renault, Victor;
Hirosawa, Katsura;
Ratanajaraya, Chanavee;
Heath, Simon;
Mimori, Tsuneyo;
Sakaguchi, Shimon;
Lathrop, Mark;
Melchers, Inga

Publication type:

Article

N-Fikser İçeren Biyolojik Gübrenin Akdeniz İklimi Koşullarında Mikrobiyolojik ve Biyokimyasal Toprak Özellikleri ile Mısır Verimine Etkisi.

Published in:

Ege Üniversitesi Ziraat Fakültesi Dergisi, 2019, v. 56, n. 4, p. 505, doi. 10.20289/zfdergi.559383

By:

AYYILDIZ, Sevde;
KAYIKÇIOĞLU, Hüseyin Hüsnü

Publication type:

Article

Potassium Fluoride-Modified Clay as a Reusable Heterogeneous Catalyst for One-Pot Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones.

Published in:

Russian Journal of Organic Chemistry, 2019, v. 55, n. 9, p. 1423, doi. 10.1134/S1070428019090240

By:

Bentahar, S.;
Taleb, M. Ait;
Sabour, A.;
Dbik, A.;
El Khomri, M.;
El Messaoudi, N.;
Lacherai, A.;
Mamouni, R.

Publication type:

Article

Synthesis of ( S)-(-)-1,4-diaryl-6-methyl-4-trifluoromethyl-3,4-dihydropyrimidine-2(1 H)-thiones.

Published in:

Russian Journal of Organic Chemistry, 2012, v. 48, n. 3, p. 430, doi. 10.1134/S1070428012030165

By:

Golovach, N.;
Sukach, V.;
Vovk, M.

Publication type:

Article

Pharmacogenetics and Adverse Events in the Use of Fluoropyrimidine in a Cohort of Cancer Patients on Standard of Care Treatment in Zimbabwe.

Published in:

Journal of Personalized Medicine, 2023, v. 13, n. 4, p. 588, doi. 10.3390/jpm13040588

By:

Afolabi, Boluwatife Lawrence;
Mazhindu, Tinashe;
Zedias, Chikwambi;
Borok, Margaret;
Ndlovu, Ntokozo;
Masimirembwa, Collen

Publication type:

Article

Genetic Variations of the DPYD Gene and Its Relationship with Ancestry Proportions in Different Ecuadorian Trihybrid Populations.

Published in:

Journal of Personalized Medicine, 2022, v. 12, n. 6, p. 950, doi. 10.3390/jpm12060950

By:

Farinango, Camila;
Gallardo-Cóndor, Jennifer;
Freire-Paspuel, Byron;
Flores-Espinoza, Rodrigo;
Jaramillo-Koupermann, Gabriela;
López-Cortés, Andrés;
Burgos, Germán;
Tejera, Eduardo;
Cabrera-Andrade, Alejandro

Publication type:

Article

Elevated Risk of Fluoropyrimidine-Associated Toxicity in European Patients with DPYD Genetic Polymorphism: A Systematic Review and Meta-Analysis.

Published in:

Journal of Personalized Medicine, 2022, v. 12, n. 2, p. N.PAG, doi. 10.3390/jpm12020225

By:

Kim, Woorim;
Cho, Young-Ah;
Kim, Dong-Chul;
Lee, Kyung-Eun

Publication type:

Article

DPYD Exome, mRNA Expression and Uracil Levels in Early Severe Toxicity to Fluoropyrimidines: An Extreme Phenotype Approach.

Published in:

Journal of Personalized Medicine, 2021, v. 11, n. 8, p. 792, doi. 10.3390/jpm11080792

By:

Villalvazo, Priscila;
Marzal-Alfaro, Belén;
García-Alfonso, Pilar;
Revuelta-Herrero, José Luis;
Thomas, Fabienne;
López-Tarruella, Sara;
García-González, Xandra;
Calvo, Aitana;
Yakoubi, Malika;
Salvador-Martín, Sara;
López-López, Flora;
Aguilar, Iker;
Sanjurjo-Sáez, María;
Martín, Miguel;
López-Fernández, Luis Andrés

Publication type:

Article

A Genotyping/Phenotyping Approach with Careful Clinical Monitoring to Manage the Fluoropyrimidines-Based Therapy: Clinical Cases and Systematic Review of the Literature.

Published in:

Journal of Personalized Medicine, 2020, v. 10, n. 3, p. 113, doi. 10.3390/jpm10030113

By:

Conti, Valeria;
De Bellis, Emanuela;
Manzo, Valentina;
Sabbatino, Francesco;
Iannello, Francesco;
Dal Piaz, Fabrizio;
Izzo, Viviana;
Charlier, Bruno;
Stefanelli, Berenice;
Torsiello, Martina;
Iannaccone, Teresa;
Coglianese, Albino;
Colucci, Francesca;
Pepe, Stefano;
Filippelli, Amelia

Publication type:

Article

DPYD, TYMS and MTHFR Genes Polymorphism Frequencies in a Series of Turkish Colorectal Cancer Patients.

Published in:

Journal of Personalized Medicine, 2018, v. 8, n. 4, p. 45, doi. 10.3390/jpm8040045

By:

Amirfallah, Arsalan;
Calibasi Kocal, Gizem;
Unal, Olcun Umit;
Ellidokuz, Hulya;
Oztop, Ilhan;
Basbinar, Yasemin

Publication type:

Article

Case report: 5-Fluorouracil treatment in patient with an important partial DPD deficiency.

Published in:

Frontiers in Oncology, 2023, p. 1, doi. 10.3389/fonc.2023.1187052

By:

Schmitt, Antonin;
Royer, Bernard;
Boidot, Romain;
Berthier, Joseph;
Ghiringhelli, François

Publication type:

Article

Biochemical, Clinical, and Genetic Characteristics of Short/Branched Chain Acyl-CoA Dehydrogenase Deficiency in Chinese Patients by Newborn Screening.

Published in:

Frontiers in Genetics, 2019, p. 1, doi. 10.3389/fgene.2019.00802

By:

Lin, Yiming;
Gao, Hongzhi;
Lin, Chunmei;
Chen, Yanru;
Zhou, Shuang;
Lin, Weihua;
Zheng, Zhenzhu;
Li, Xiaoqing;
Li, Min;
Fu, Qingliu

Publication type:

Article

Analysis of very important pharmacogene variants in the Tibetan population from China.

Published in:

Clinical & Experimental Pharmacology & Physiology, 2021, v. 48, n. 5, p. 668, doi. 10.1111/1440-1681.13327

By:

Rong, Hao;
Dong, Hongzhi;
He, Xue;
Yuan, Dongya;
Bai, Mei;
Wang, Li;
Liu, Tao;
He, Yongjun;
Zheng, Jianwen;
Wang, Yuhe;
Jin, Tianbo

Publication type:

Article