Works about DIHYDROPYRIMIDINE dehydrogenase
Results: 311
Indirect assessment of dihydropyrimidine dehydrogenase activity in cats.
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- Veterinary & Comparative Oncology, 2013, v. 11, n. 4, p. 265, doi. 10.1111/vco.12064
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- Article
Frontier Molecular Orbital Energies as Descriptors for Prediction of Antiglycating Activity of N-Hydroxybenzoyl-Substituted Thymine and Uracil**.
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- Pharmaceutical Chemistry Journal, 2021, v. 55, n. 7, p. 648, doi. 10.1007/s11094-021-02474-1
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- Article
Features of the behavior of 5-substituted N(3)-acyl-4,6-diaryl-3,4-dihydropyrimidin-2(1 H)-ones under electron ionization.
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- Journal of Structural Chemistry, 2012, v. 53, n. 1, p. 164, doi. 10.1134/S0022476612010222
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- Article
DPYD Variants to Predict 5-FU toxicity: the Ultimate Proof.
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- JNCI: Journal of the National Cancer Institute, 2014, v. 106, n. 12, p. 1, doi. 10.1093/jnci/dju351
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- Article
DPYD Variants as Predictors of 5-fluorouraciltoxicity in Adjuvant colon cancer treatment (NcctG N0147).
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- JNCI: Journal of the National Cancer Institute, 2014, v. 106, n. 12, p. 1, doi. 10.1093/jnci/dju298
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- Article
DPYD Variants to Predict 5-FU Toxicity: The Ultimate Proof.
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- 2014
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- Editorial
Purification and characterization of dihydropyrimidine dehydrogenase enzyme from sheep liver and determination of the effects of some anaesthetic and antidepressant drugs on the enzyme activity.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2016, v. 31, n. 6, p. 1335, doi. 10.3109/14756366.2015.1132710
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- Article
Characterization of Genes for Beef Marbling Based on Applying Gene Coexpression Network.
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- International Journal of Genomics, 2014, p. 1, doi. 10.1155/2014/708562
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- Article
Enhanced efficacy of 5-fluorouracil combined with chrysin in treating colorectal cancer in BALB/c mice: Impact on β-catenin and inducible nitric oxide synthase expression.
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- Indian Journal of Natural Products & Resources, 2023, v. 14, n. 2, p. 229, doi. 10.56042/ijnpr.v14i2.4207
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- Article
The Allosteric Regulation of Β-Ureidopropionase Depends on Fine-Tuned Stability of Active-Site Loops and Subunit Interfaces.
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- Biomolecules (2218-273X), 2023, v. 13, n. 12, p. 1763, doi. 10.3390/biom13121763
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- Article
Complexed Crystal Structure of the Dihydroorotase Domain of Human CAD Protein with the Anticancer Drug 5-Fluorouracil.
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- Biomolecules (2218-273X), 2023, v. 13, n. 1, p. 149, doi. 10.3390/biom13010149
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- Article
Development of Artificial System to Induce Chromatin Loosening in Saccharomyces cerevisiae.
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- Biomolecules (2218-273X), 2022, v. 12, n. 8, p. 1138, doi. 10.3390/biom12081138
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- Article
The Administration of Chitosan-Tripolyphosphate-DNA Nanoparticles to Express Exogenous SREBP1a Enhances Conversion of Dietary Carbohydrates into Lipids in the Liver of Sparus aurata.
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- Biomolecules (2218-273X), 2019, v. 9, n. 8, p. 297, doi. 10.3390/biom9080297
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- Article
Rare Dihydropyrimidine Dehydrogenase Variants and Toxicity by Floropyrimidines: A Case Report.
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- Frontiers in Oncology, 2019, p. N.PAG, doi. 10.3389/fonc.2019.00139
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- Article
Assessment of Oral Vancomycin-Induced Alterations in Gut Bacterial Microbiota and Metabolome of Healthy Men.
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- Frontiers in Cellular & Infection Microbiology, 2021, v. 11, p. 1, doi. 10.3389/fcimb.2021.629438
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- Article
Osteogenesis Imperfecta, Pseudoachalasia, and Gastric Cancer.
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- Case Reports in Gastrointestinal Medicine, 2015, v. 2015, p. 1, doi. 10.1155/2015/685459
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- Article
Identifying a Novel DPYD Polymorphism Associated with Severe Toxicity to 5-FU Chemotherapy in a Saudi Patient.
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- Case Reports in Genetics, 2019, p. 1, doi. 10.1155/2019/5150725
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- Article
Development of a Pharmacogenetic Lab-on-Chip Assay Based on the In-Check Technology to Screen for Genetic Variations Associated to Adverse Drug Reactions to Common Chemotherapeutic Agents.
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- Biosensors (2079-6374), 2020, v. 10, n. 12, p. 202, doi. 10.3390/bios10120202
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- Article
Probiotic-Fermented Distillers Grain Alters the Rumen Microbiome, Metabolome, and Enzyme Activity, Enhancing the Immune Status of Finishing Cattle.
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- Animals (2076-2615), 2023, v. 13, n. 24, p. 3774, doi. 10.3390/ani13243774
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- Article
The Activity of 5-Flurouracil Metabolizing Enzyme Dihydropyrimidine Dehydrogenase(DPD) and its Association with Tumor Progression and Markers (CEA, CA19.9) in Patients with Colorectal Cancer.
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- Indian Journal of Public Health Research & Development, 2019, v. 10, n. 10, p. 2363, doi. 10.5958/0976-5506.2019.03212.1
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- Article
Expression level of dihydropyrimidine dehydrogenase is associated with clinical outcome in patients with T1G3 bladder cancer treated with Bacillus Calmette-Guerin.
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- BMC Research Notes, 2014, p. 1, doi. 10.1186/1756-0500-7-646
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- Article
Multiple mutations across the succinate dehydrogenase gene complex are associated with boscalid resistance in Didymella tanaceti in pyrethrum.
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- PLoS ONE, 2019, v. 14, n. 6, p. 1, doi. 10.1371/journal.pone.0218569
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- Article
Repair of chromosomal abasic sites in vivo involves at least three different repair pathways.
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- EMBO Journal, 2000, v. 19, n. 20, p. 5542, doi. 10.1093/emboj/19.20.5542
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- Article
Human DNA tumor viruses evade uracil-mediated antiviral immunity.
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- PLoS Pathogens, 2023, v. 18, n. 3, p. 1, doi. 10.1371/journal.ppat.1011252
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- Article
Relationship Between the DPD and TS mRNA Expression and the Response to S-1-Based Chemotherapy and Prognosis in Patients with Advanced Gastric Cancer.
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- Cell Biochemistry & Biophysics, 2015, v. 71, n. 3, p. 1653, doi. 10.1007/s12013-014-0387-5
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- Article
Effective and economical column-based method for RNA isolation from animal cells.
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- Biotechnology Letters, 2019, v. 41, n. 8/9, p. 915, doi. 10.1007/s10529-019-02700-7
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- Article
Role of thymidylate synthase and dihydropyrimidine dehydrogenase mRNA expressions in gallbladder carcinoma.
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- Surgery Today, 2012, v. 42, n. 6, p. 565, doi. 10.1007/s00595-012-0118-8
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- Article
Substrate Diversity of L-Threonic Acid Dehydrogenase Homologs.
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- Biochemistry (00062979), 2020, v. 85, n. 4, p. 463, doi. 10.1134/S0006297920040069
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- Article
Capecitabine—A "Permanent Mission" in Head and Neck Cancers "War Council"?
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- Journal of Clinical Medicine, 2022, v. 11, n. 19, p. 5582, doi. 10.3390/jcm11195582
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- Article
In Vitro Assessment of Fluoropyrimidine-Metabolizing Enzymes: Dihydropyrimidine Dehydrogenase, Dihydropyrimidinase, and β-Ureidopropionase.
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- Journal of Clinical Medicine, 2020, v. 9, n. 8, p. 2342, doi. 10.3390/jcm9082342
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- Article
DPYD genotyping and dihydropyrimidine dehydrogenase (DPD) phenotyping in clinical oncology. A clinically focused minireview.
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- Basic & Clinical Pharmacology & Toxicology, 2022, v. 131, n. 5, p. 325, doi. 10.1111/bcpt.13782
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- Article
Association and prediction of severe 5-fluorouracil toxicity with dihydropyrimidine dehydrogenase gene polymorphisms: A meta-analysis.
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- Biomedical Reports, 2015, v. 3, n. 6, p. 879, doi. 10.3892/br.2015.513
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- Article
Pharmacogenetics and Adverse Events in the Use of Fluoropyrimidine in a Cohort of Cancer Patients on Standard of Care Treatment in Zimbabwe.
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- Journal of Personalized Medicine, 2023, v. 13, n. 4, p. 588, doi. 10.3390/jpm13040588
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- Article
Genetic Variations of the DPYD Gene and Its Relationship with Ancestry Proportions in Different Ecuadorian Trihybrid Populations.
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- Journal of Personalized Medicine, 2022, v. 12, n. 6, p. 950, doi. 10.3390/jpm12060950
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- Article
Elevated Risk of Fluoropyrimidine-Associated Toxicity in European Patients with DPYD Genetic Polymorphism: A Systematic Review and Meta-Analysis.
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- Journal of Personalized Medicine, 2022, v. 12, n. 2, p. N.PAG, doi. 10.3390/jpm12020225
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- Article
DPYD Exome, mRNA Expression and Uracil Levels in Early Severe Toxicity to Fluoropyrimidines: An Extreme Phenotype Approach.
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- Journal of Personalized Medicine, 2021, v. 11, n. 8, p. 792, doi. 10.3390/jpm11080792
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- Article
A Genotyping/Phenotyping Approach with Careful Clinical Monitoring to Manage the Fluoropyrimidines-Based Therapy: Clinical Cases and Systematic Review of the Literature.
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- Journal of Personalized Medicine, 2020, v. 10, n. 3, p. 113, doi. 10.3390/jpm10030113
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- Article
DPYD, TYMS and MTHFR Genes Polymorphism Frequencies in a Series of Turkish Colorectal Cancer Patients.
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- Journal of Personalized Medicine, 2018, v. 8, n. 4, p. 45, doi. 10.3390/jpm8040045
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- Article
Case report: A case of severe capecitabine toxicity due to confirmed in trans compound heterozygosity of a common and rare DPYD variant.
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- Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1459565
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- Article
Editorial: State of the science of pharmacogenomics implementation in healthcare systems and communities.
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- Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1463384
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- Article
A novel series of human dihydroorotate dehydrogenase inhibitors discovered by in vitro screening: inhibition activity and crystallographic binding mode.
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- FEBS Open Bio, 2019, v. 9, n. 8, p. 1348, doi. 10.1002/2211-5463.12658
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- Article
A patient with a severe allergic reaction secondary to Efudix 5% cream.
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- Clinical & Experimental Dermatology, 2023, v. 48, n. 6, p. 699, doi. 10.1093/ced/llad072
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- Article
A PRACTICAL GREEN SYNTHESIS OF THIAZINE DERIVATIVES USING PHASE TRANSFER CATALYST.
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- Rasayan Journal of Chemistry, 2018, v. 11, n. 3, p. 1294, doi. 10.31788/RJC.2018.1134012
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- Article
Pharmacogenomic Assessment of Patients with Colorectal Cancer and Potential Treatments.
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- Pharmacogenomics & Personalized Medicine, 2020, v. 13, p. 601, doi. 10.2147/PGPM.S253586
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- Article
Metabolic engineering of a fast-growing cyanobacterium Synechococcus elongatus PCC 11801 for photoautotrophic production of succinic acid.
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- Biotechnology for Biofuels, 2020, v. 13, n. 1, p. 1, doi. 10.1186/s13068-020-01727-7
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- Article
Leukoencephalopathy with transient splenial lesions related to 5‐fluorouracil or capecitabine.
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- European Journal of Neurology, 2021, v. 28, n. 7, p. 2396, doi. 10.1111/ene.14857
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- Article
S100A16-induced adipogenesis is associated with up-regulation of 11 β-hydroxysteroid dehydrogenase type 1 (11β-HSD1).
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- Bioscience Reports, 2019, v. 39, n. 9, p. 1, doi. 10.1042/BSR20182042
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- Article
Predictive value of clinical toxicities of chemotherapy with fluoropyrimidines and oxaliplatin in colorectal cancer by DPYD and GSTP1 gene polymorphisms.
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- World Journal of Surgical Oncology, 2020, v. 18, n. 1, p. 1, doi. 10.1186/s12957-020-02103-3
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- Article
The Stereoselectivity and Hydrolysis Efficiency of Recombinant d-Hydantoinase from Vigna angularis Against 5-Benzylhydantoin Derivatives with Halogen and Methyl Substituents.
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- Applied Biochemistry & Biotechnology, 2015, v. 175, n. 2, p. 698, doi. 10.1007/s12010-014-1313-4
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- Article
Early-Onset 5-Fluorouracil Toxicity in a Patient Negative for Dihydropyrimidine Dehydrogenase Mutations: The Clinical Course of Reversal with Uridine Triacetate.
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- Pharmacotherapy, 2016, v. 36, n. 11, p. e178, doi. 10.1002/phar.1841
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- Article