Works matching DE "DIHYDROPYRIMIDINE dehydrogenase"
Results: 311
Effective and economical column-based method for RNA isolation from animal cells.
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- Biotechnology Letters, 2019, v. 41, n. 8/9, p. 915, doi. 10.1007/s10529-019-02700-7
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- Article
Role of thymidylate synthase and dihydropyrimidine dehydrogenase mRNA expressions in gallbladder carcinoma.
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- Surgery Today, 2012, v. 42, n. 6, p. 565, doi. 10.1007/s00595-012-0118-8
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- Article
Synthesis and structure of functionalized podands containing 4,7-dihydrotetrazolo[1,5-а]pyrimidine ring. Differently substituted dihydropyrimidine podands.
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- Chemistry of Heterocyclic Compounds, 2018, v. 54, n. 10, p. 971, doi. 10.1007/s10593-018-2373-0
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- Article
Alkylation of Tetrahydropyrimidine-2-thiones with Ethyl Chloroacetate.
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- Chemistry of Heterocyclic Compounds, 2014, v. 49, n. 11, p. 1681, doi. 10.1007/s10593-014-1420-8
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- Article
干预自噬影响DPD的表达促进5-FU抗结直肠 癌疗效的实验研究.
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- China Oncology, 2022, v. 32, n. 12, p. 1199, doi. 10.19401/j.cnki.1007-3639.2022.12.008
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- Article
Developing DPYD Genotyping Method for Personalized Fluoropyrimidines Therapy.
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- Journal of Applied Laboratory Medicine, 2024, v. 9, n. 2, p. 295, doi. 10.1093/jalm/jfad092
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- Article
Purification and characterization of dihydropyrimidine dehydrogenase enzyme from sheep liver and determination of the effects of some anaesthetic and antidepressant drugs on the enzyme activity.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2016, v. 31, n. 6, p. 1335, doi. 10.3109/14756366.2015.1132710
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- Article
Enhanced efficacy of 5-fluorouracil combined with chrysin in treating colorectal cancer in BALB/c mice: Impact on β-catenin and inducible nitric oxide synthase expression.
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- Indian Journal of Natural Products & Resources, 2023, v. 14, n. 2, p. 229, doi. 10.56042/ijnpr.v14i2.4207
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- Article
New Insights into rice pyrimidine catabolic enzymes.
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- Frontiers in Plant Science, 2023, v. 14, p. 1, doi. 10.3389/fpls.2023.1079778
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- Article
Commentary: The pharmacogenomic landscape of an Indigenous Australian population.
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- Frontiers in Pharmacology, 2024, p. 01, doi. 10.3389/fphar.2024.1373056
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- Article
Exploring the impact of MiR-92a-3p on FOLFOX chemoresistance biomarker genes in colon cancer cell lines.
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- Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1376638
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- Article
Implementing pharmacogenetic testing in fluoropyrimidine-treated cancer patients: DPYD genotyping to guide chemotherapy dosing in Greece.
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- Frontiers in Pharmacology, 2023, p. 01, doi. 10.3389/fphar.2023.1248898
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- Article
Implementation of pharmacogenetic testing in oncology: DPYD-guided dosing to prevent fluoropyrimidine toxicity in British Columbia.
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- Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1257745
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- Article
Pharmacogenomic-guided dosing of fluoropyrimidines beyond DPYD: time for a polygenic algorithm?
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- Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1184523
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- Article
Probiotic-Fermented Distillers Grain Alters the Rumen Microbiome, Metabolome, and Enzyme Activity, Enhancing the Immune Status of Finishing Cattle.
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- Animals (2076-2615), 2023, v. 13, n. 24, p. 3774, doi. 10.3390/ani13243774
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- Article
Dihydropyrimidine dehydrogenase deficiency in patients with severe toxicity after 5-fluorouracil: a retrospective single-center study.
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- Annals of Gastroenterology, 2021, v. 34, n. 1, p. 68, doi. 10.20524/aog.2020.0551
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- Article
Single virus fingerprinting by widefield interferometric defocus-enhanced mid-infrared photothermal microscopy.
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- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-42439-4
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- Article
Pharmacokinetic variables of medium molecular weight cross linked chitosan nanoparticles to enhance the bioavailability of 5-fluorouracil and reduce the acute oral toxicity.
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- Drug Delivery, 2021, v. 28, n. 1, p. 1569, doi. 10.1080/10717544.2021.1944398
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- Article
Tamoxifen resistance alters sensitivity to 5-fluorouracil in a subset of estrogen receptor-positive breast cancer.
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- PLoS ONE, 2021, v. 16, n. 6, p. 1, doi. 10.1371/journal.pone.0252822
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- Article
TERAPIJSKI PRISTUP KARCINOMU CRIJEVA KOD PACIJENTA S MIASTENIJOM GRAVIS: PRIKAZ SLUČAJA.
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- Lijecnicki Vjesnik, 2024, v. 146, p. 39, doi. 10.26800/LV-146-supl4-2
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- Article
Potential targeting of the stroke by means of the layered nano- and microparticles.
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- Ajastan Kensabanakan Handes, 2023, v. 75, p. 73
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- Article
Crystal structure of 6-oxo-4-propyl-2-(propylthio)-1,6-dihydropyrimidine-5-carbonitrile, C<sub>11</sub>H<sub>15</sub>N<sub>3</sub>OS.
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- Zeitschrift für Kristallographie / New Crystal Structures, 2016, v. 231, n. 2, p. 583, doi. 10.1515/ncrs-2015-0198
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- Article
Somatic copy number changes in DPYD are associated with lower risk of recurrence in triple-negative breast cancers.
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- British Journal of Cancer, 2013, v. 109, n. 9, p. 2347, doi. 10.1038/bjc.2013.621
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- Article
Upregulation of ERCC1 and DPD expressions after oxaliplatin-based first-line chemotherapy for metastatic colorectal cancer.
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- British Journal of Cancer, 2012, v. 107, n. 12, p. 1950, doi. 10.1038/bjc.2012.502
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- Article
Predictive value of clinical toxicities of chemotherapy with fluoropyrimidines and oxaliplatin in colorectal cancer by DPYD and GSTP1 gene polymorphisms.
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- World Journal of Surgical Oncology, 2020, v. 18, n. 1, p. 1, doi. 10.1186/s12957-020-02103-3
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- Article
Comparative Analysis of Transcriptome Responses to Cold Stress in Galeruca daurica (Coleoptera: Chrysomelidae).
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- Journal of Insect Science, 2019, v. 19, n. 6, p. N.PAG, doi. 10.1093/jisesa/iez109
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- Article
Phase II multi-institutional prospective randomized trial comparing S-1 plus paclitaxel with paclitaxel alone as second-line chemotherapy in S-1 pretreated gastric cancer (CCOG0701).
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- International Journal of Clinical Oncology, 2016, v. 21, n. 3, p. 557, doi. 10.1007/s10147-015-0919-z
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- Article
Combined use of 177Lu-DOTATATE and metronomic capecitabine (Lu-X) in FDG-positive gastro-entero-pancreatic neuroendocrine tumors.
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- European Journal of Nuclear Medicine & Molecular Imaging, 2021, v. 48, n. 10, p. 3260, doi. 10.1007/s00259-021-05236-z
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- Article
Influence of age on pharmacokinetics of capecitabine and its metabolites in older adults with cancer: a pilot study.
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- Cancer Chemotherapy & Pharmacology, 2023, v. 92, n. 2, p. 135, doi. 10.1007/s00280-023-04552-5
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- Article
Precision fluoropyrimidines dosing in a compound heterozygous variant carrier of the DPYD gene: a case report.
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- 2023
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- Case Study
Assay performance and stability of uracil and dihydrouracil in clinical practice.
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- Cancer Chemotherapy & Pharmacology, 2023, v. 91, n. 3, p. 257, doi. 10.1007/s00280-023-04518-7
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- Article
Fluoropyrimidine-associated toxicity and DPYD variants c.85T>C, c.496A>G, and c.1236G>A: impact of haplotype.
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- Cancer Chemotherapy & Pharmacology, 2023, v. 91, n. 1, p. 97, doi. 10.1007/s00280-022-04491-7
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- Article
Pretherapeutic screening for Dihydropyrimidine deshydrogenase deficiency in measuring uracilemia in dialysis patients leads to a high rate of falsely positive results.
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- 2021
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- Publication type:
- journal article
Detecting DPD deficiency: when perfect is the enemy of good.
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- 2021
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- Publication type:
- Letter
Preemptive screening of DPYD as part of clinical practice: high prevalence of a novel exon 4 deletion in the Finnish population.
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- Cancer Chemotherapy & Pharmacology, 2021, v. 87, n. 5, p. 657, doi. 10.1007/s00280-021-04236-y
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- Article
Pharmacokinetic and toxicodynamic evaluation of 5-fluorouracil administration after major hepatectomy in a rat model.
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- 2020
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- Publication type:
- journal article
MicroRNA-552 deficiency mediates 5-fluorouracil resistance by targeting SMAD2 signaling in DNA-mismatch-repair-deficient colorectal cancer.
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- 2019
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- Publication type:
- journal article
PRIMUM NON NOCERE: now and again an echo of DPD with capecitabine.
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- 2017
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- Publication type:
- Letter
Patients homozygous for DPYD c.1129-5923C>G/haplotype B3 have partial DPD deficiency and require a dose reduction when treated with fluoropyrimidines.
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- 2016
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- Publication type:
- journal article
Effects of a bolus injection of 5-fluorouracil on dihydropyrimidine dehydrogenase activity in rats receiving continuous infusion of 5-fluorouracil.
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- 2016
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- Publication type:
- journal article
Benefit of uridine triacetate (Vistogard) in rescuing severe 5-fluorouracil toxicity in patients with dihydropyrimidine dehydrogenase (DPYD) deficiency.
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- 2016
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- Publication type:
- journal article
Influence of metastatic disease on the usefulness of uracil pharmacokinetics as a screening tool for DPD activity in colorectal cancer patients.
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- Cancer Chemotherapy & Pharmacology, 2015, v. 76, n. 1, p. 47, doi. 10.1007/s00280-015-2746-3
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- Publication type:
- Article
Validation of a fast and low-cost alkaline lysis method for gDNA extraction in a pharmacogenetic context.
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- Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 5, p. 1095, doi. 10.1007/s00280-015-2729-4
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- Publication type:
- Article
Pretherapeutic uracil and dihydrouracil levels in saliva of colorectal cancer patients are associated with toxicity during adjuvant 5-fluorouracil-based chemotherapy.
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- Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 4, p. 757, doi. 10.1007/s00280-014-2553-2
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- Article
First-in-human, phase I dose-escalation study of single and multiple doses of a first-in-class enhancer of fluoropyrimidines, a dUTPase inhibitor (TAS-114) in healthy male volunteers.
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- Cancer Chemotherapy & Pharmacology, 2014, v. 73, n. 3, p. 577, doi. 10.1007/s00280-014-2383-2
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- Publication type:
- Article
<sup>13</sup>C-uracil breath test to predict 5-fluorouracil toxicity in gastrointestinal cancer patients.
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- Cancer Chemotherapy & Pharmacology, 2013, v. 72, n. 6, p. 1273, doi. 10.1007/s00280-013-2309-4
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- Article
Frontier Molecular Orbital Energies as Descriptors for Prediction of Antiglycating Activity of N-Hydroxybenzoyl-Substituted Thymine and Uracil**.
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- Pharmaceutical Chemistry Journal, 2021, v. 55, n. 7, p. 648, doi. 10.1007/s11094-021-02474-1
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- Article
Reaction of 6-methyl-2-(2-oxo-2-phenyl-ethylidene)-2,3-dihydropyrimidin-4(1 H)-one with hydrazine and hydroxylamine.
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- Chemistry of Heterocyclic Compounds, 2013, v. 48, n. 10, p. 1487, doi. 10.1007/s10593-013-1162-z
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- Article
Substrate Diversity of L-Threonic Acid Dehydrogenase Homologs.
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- Biochemistry (00062979), 2020, v. 85, n. 4, p. 463, doi. 10.1134/S0006297920040069
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- Article
DIHYDROPYRIMIDINE DEHYDROGENASE ACTIVITY AND OTHER BIOMOLECULES IN THE SERA OF CANCER PATIENTS BEFORE AND AFTER TREATMENT WITH 5-FLUOROURACIL.
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- Biochemical & Cellular Archives, 2021, v. 21, n. 2, p. 4799
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- Article