Works matching DE "DIHYDROOROTATE dehydrogenase"
Results: 178
Treatment of Invasive Aspergillosis: How It's Going, Where It's Heading.
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- Mycopathologia, 2023, v. 188, n. 5, p. 667, doi. 10.1007/s11046-023-00727-z
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- Article
DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation.
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- eLife, 2024, p. 1, doi. 10.7554/eLife.87292
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- Article
New Insights into rice pyrimidine catabolic enzymes.
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- Frontiers in Plant Science, 2023, v. 14, p. 1, doi. 10.3389/fpls.2023.1079778
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- Article
Dihydroorotate dehydrogenase inhibitor olorofim has potent in vitro activity against Microascus/Scopulariopsis, Rasamsonia, Penicillium and Talaromyces species.
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- Mycoses, 2023, v. 66, n. 3, p. 242, doi. 10.1111/myc.13548
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In vitro activity of olorofim against clinical isolates of the Fusarium oxysporum and Fusarium solani species complexes.
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- Mycoses, 2021, v. 64, n. 7, p. 748, doi. 10.1111/myc.13273
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Case of femoral pseudarthrosis due to Scedosporium apiospermum in an immunocompetent patient with successful conservative treatment and review of literature.
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- Mycoses, 2018, v. 61, n. 6, p. 400, doi. 10.1111/myc.12739
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- Article
Cloning and Characterization of Yak DHODH Gene and Its Functional Studies in a Bisphenol S-Induced Ferroptosis Model of Fetal Fibroblasts.
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- Animals (2076-2615), 2023, v. 13, n. 24, p. 3832, doi. 10.3390/ani13243832
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Lysyl oxidase-like 3 restrains mitochondrial ferroptosis to promote liver cancer chemoresistance by stabilizing dihydroorotate dehydrogenase.
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- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-38753-6
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NEUROPATIA PERIFÉRICA E LEFLUNOMIDA.
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- Acta Reumatológica Portuguesa, 2011, v. 36, n. 3, p. 313
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Crystal structure of 4-ethyl-2-{[(4-nitrophenyl)methyl]sulfanyl}-6-oxo-1,6-dihydropyrimidine-5-carbonitrile, C<sub>14</sub>H<sub>12</sub>N<sub>4</sub>O<sub>3</sub>S.
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- Zeitschrift für Kristallographie / New Crystal Structures, 2022, v. 237, n. 5, p. 811, doi. 10.1515/ncrs-2022-0272
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The mononuclear metal center of type-I dihydroorotase from aquifex aeolicus.
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- BMC Biochemistry, 2013, v. 14, n. 1, p. 1, doi. 10.1186/1471-2091-14-36
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Teriflunomide treatment exacerbates cardiac ischemia reperfusion injury in isolated rat hearts.
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- Cardiovascular Drugs & Therapy, 2023, v. 37, n. 5, p. 1021, doi. 10.1007/s10557-022-07341-z
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- Article
IN-SILICO MOLECULAR DOCKING AND ADME EVALUATION OF FICUS RACEMOSA PHYTOCONSTITUENTS TARGETING GLUCOKINASE AND DIHYDROOROTATE DEHYDROGENASE FOR DIABETES MANAGEMENT.
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- Biochemical & Cellular Archives, 2024, p. 3477, doi. 10.51470/bca.2024.24.1-S.3477
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Synthesis of Substituted Aryl Incorporated Oxazolo[4,5-b]Pyridine-Triazole Derivatives: Anticancer Evaluation and Molecular Docking Studies.
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- Polycyclic Aromatic Compounds, 2023, v. 43, n. 1, p. 915, doi. 10.1080/10406638.2021.2021256
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Molecular Mechanisms of Ferroptosis and Relevance to Cardiovascular Disease.
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- Cells (2073-4409), 2022, v. 11, n. 17, p. 2726, doi. 10.3390/cells11172726
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Inhibition of the mitochondrial pyrimidine biosynthesis enzyme dihydroorotate dehydrogenase by doxorubicin and brequinar sensitizes cancer cells to TRAIL-induced apoptosis.
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- Oncogene, 2014, v. 33, n. 27, p. 3538, doi. 10.1038/onc.2013.313
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Correction: Vidofludimus inhibits porcine reproductive and respiratory syndrome virus infection by targeting dihydroorotate dehydrogenase.
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- 2024
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- Correction Notice
Vidofludimus inhibits porcine reproductive and respiratory syndrome virus infection by targeting dihydroorotate dehydrogenase.
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- Veterinary Research, 2023, v. 54, n. 1, p. 1, doi. 10.1186/s13567-023-01251-0
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Teriflunomide Concentrations in Cerebrospinal Fluid and Plasma in Patients with Multiple Sclerosis: A Pharmacokinetic Study.
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- CNS Drugs, 2023, v. 37, n. 2, p. 181, doi. 10.1007/s40263-023-00985-x
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Inhibition of pyrimidine biosynthesis by strobilurin derivatives induces differentiation of acute myeloid leukemia cells.
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- Leukemia & Lymphoma, 2022, v. 63, n. 5, p. 1202, doi. 10.1080/10428194.2021.2008382
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Targeting mitochondrial metabolism in acute myeloid leukemia.
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- Leukemia & Lymphoma, 2022, v. 63, n. 3, p. 530, doi. 10.1080/10428194.2021.1992759
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- Article
Teriflunomide attenuates immunopathological changes in the Dark Agouti rat model of experimental autoimmune encephalomyelitis.
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- Frontiers in Neurology, 2013, v. 4, p. 1, doi. 10.3389/fneur.2013.00169
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- Article
SYNTHESIS OF A NOVEL CHALCONE DERIVATIVE FROM MYRISTICIN FOR SKIN CANCER PREVENTIVE ACTIVITY.
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- Rasayan Journal of Chemistry, 2021, v. 14, n. 3, p. 1493, doi. 10.31788/RJC.2021.1436312
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- Article
Characterisation of putative class 1A DHODH-like proteins from Mucorales and dematiaceous mould species.
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- PLoS ONE, 2023, v. 18, n. 8, p. 1, doi. 10.1371/journal.pone.0289441
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GSK-3β inhibition alleviates arthritis pain via reducing spinal mitochondrial reactive oxygen species level and inflammation.
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- PLoS ONE, 2023, v. 17, n. 4, p. 1, doi. 10.1371/journal.pone.0284332
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Identification of a dihydroorotate dehydrogenase inhibitor that inhibits cancer cell growth by proteomic profiling.
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- Oncology Research, 2023, v. 31, n. 6, p. 833, doi. 10.32604/or.2023.030241
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- Article
A Combined Chemical, Computational, and In Vitro Approach Identifies SBL-105 as Novel DHODH Inhibitor in Acute Myeloid Leukemia Cells.
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- Oncology Research, 2020, v. 28, n. 9, p. 899, doi. 10.3727/096504021X16281573507558
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- Article
Selective eradication of pluripotent stem cells by inhibiting DHODH activity.
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- Stem Cells, 2021, v. 39, n. 1, p. 33, doi. 10.1002/stem.3290
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- Article
Quantitative Systems Toxicology Modeling Informed Safe Dose Selection of Emvododstat in Acute Myeloid Leukemia Patients.
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- Clinical Pharmacology & Therapeutics, 2024, v. 115, n. 3, p. 525, doi. 10.1002/cpt.3136
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- Article
Upregulation of cytidine deaminase in NAT1 knockout breast cancer cells.
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- Journal of Cancer Research & Clinical Oncology, 2023, v. 149, n. 8, p. 5047, doi. 10.1007/s00432-022-04436-w
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Control of Echinochloa spp. and Leptochloa fascicularis with the novel dihydroorotate dehydrogenase inhibitor herbicide tetflupyrolimet in California water-seeded rice.
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- Weed Technology, 2024, v. 38, n. 1, p. 1, doi. 10.1017/wet.2024.21
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Protein-lipid interactions of human dihydroorotate dehydrogenase and three mutants associated with Miller syndrome.
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- Nucleosides, Nucleotides & Nucleic Acids, 2022, v. 41, n. 12, p. 1337, doi. 10.1080/15257770.2022.2039393
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Protein production, kinetic and biophysical characterization of three human dihydroorotate dehydrogenase mutants associated with Miller syndrome.
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- Nucleosides, Nucleotides & Nucleic Acids, 2022, v. 41, n. 12, p. 1318, doi. 10.1080/15257770.2021.2023749
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The pathway to pyrimidines: The essential focus on dihydroorotate dehydrogenase, the mitochondrial enzyme coupled to the respiratory chain.
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- Nucleosides, Nucleotides & Nucleic Acids, 2020, v. 39, n. 10-12, p. 1281, doi. 10.1080/15257770.2020.1723625
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Preparation of human dihydroorotate dehydrogenase for interaction studies with lipid bilayers.
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- Nucleosides, Nucleotides & Nucleic Acids, 2020, v. 39, n. 10-12, p. 1306, doi. 10.1080/15257770.2019.1708100
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Re-evaluation of Brequinar sodium, a dihydroorotate dehydrogenase inhibitor.
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- Nucleosides, Nucleotides & Nucleic Acids, 2018, v. 37, n. 12, p. 666, doi. 10.1080/15257770.2018.1508692
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- Article
Antipyrimidine effects of five different pyrimidine de novo synthesis inhibitors in three head and neck cancer cell lines.
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- Nucleosides, Nucleotides & Nucleic Acids, 2018, v. 37, n. 6, p. 329, doi. 10.1080/15257770.2018.1460479
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Orotate (orotic acid): An essential and versatile molecule.
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- Nucleosides, Nucleotides & Nucleic Acids, 2016, v. 35, n. 10-12, p. 566, doi. 10.1080/15257770.2016.1147580
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Diverse evolutionary pathways challenge the use of collateral sensitivity as a strategy to suppress resistance.
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- eLife, 2023, p. 1, doi. 10.7554/eLife.85023
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A pharmacokinetic–pharmacodynamic model for chemoprotective agents against malaria.
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- CPT: Pharmacometrics & Systems Pharmacology, 2023, v. 12, n. 1, p. 50, doi. 10.1002/psp4.12875
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- Article
Rational Design of Benzylidenehydrazinyl-Substituted Thiazole Derivatives as Potent Inhibitors of Human Dihydroorotate Dehydrogenase with in Vivo Anti-arthritic Activity.
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- Scientific Reports, 2015, p. 1, doi. 10.1038/srep14836
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Hailey–Hailey disease (benign familial pemphigus) responsive to treatment with ocrelizumab for multiple sclerosis.
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- British Journal of Dermatology, 2023, v. 189, n. 2, p. 232, doi. 10.1093/bjd/ljad101
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BI25: Eruptive keratoacanthomas in association with leflunomide and adalimumab treatment for psoriatic arthritis: an insight into cancer prevention?
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- British Journal of Dermatology, 2022, v. 187, p. 115, doi. 10.1111/bjd.21367
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- Article
Leflunomide: dermatologic perspective.
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- Journal of Dermatological Treatment, 2013, v. 24, n. 2, p. 89, doi. 10.3109/09546634.2011.595383
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- Article
Identification of DHODH as a therapeutic target in small cell lung cancer.
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- Science Translational Medicine, 2019, v. 11, n. 517, p. 1, doi. 10.1126/scitranslmed.aaw7852
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Targeting pyrimidine synthesis accentuates molecular therapy response in glioblastoma stem cells.
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- Science Translational Medicine, 2019, v. 11, n. 504, p. 1, doi. 10.1126/scitranslmed.aau4972
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- Article
Teriflunomide treatment for multiple sclerosis modulates T cell mitochondrial respiration with affinity-dependent effects.
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- Science Translational Medicine, 2019, v. 11, n. 490, p. N.PAG, doi. 10.1126/scitranslmed.aao5563
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- Article
Exploring the Venom Gland Transcriptome of Bothrops asper and Bothrops jararaca : De Novo Assembly and Analysis of Novel Toxic Proteins.
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- Toxins, 2024, v. 16, n. 12, p. 511, doi. 10.3390/toxins16120511
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- Article
Teriflunomide-induced Palmoplantar Lichenoid Eruption: A Case Report.
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- Acta Dermato-Venereologica, 2024, v. 104, p. 1, doi. 10.2340/actadv.v104.40967
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- Article
The Novel h DHODH Inhibitor MEDS433 Prevents Influenza Virus Replication by Blocking Pyrimidine Biosynthesis.
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- Viruses (1999-4915), 2022, v. 14, n. 10, p. N.PAG, doi. 10.3390/v14102281
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- Article