Works matching DE "DEMETHYLASE"

Results: 524

Modulation of an evolutionarily conserved epigenetic regulon controlling abscisic acid catabolism enhances drought tolerance in wheat.

Published in:

New Phytologist, 2025, v. 247, n. 4, p. 1777, doi. 10.1111/nph.70302

By:

Li, Yunzhen;
Jin, Liujie;
Li, Wanying;
Wang, Ke;
Su, Handong;
Mao, Hailiang;
Chen, Wei;
Lan, Caixia;
Li, Qiang;
Kaufmann, Kerstin;
Yan, Wenhao

Publication type:

Article

Natural variation in histone demethylase GmLDL2 confers flowering time divergence for geographical expansion in soybean.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-61328-6

By:

Liu, Mengshi;
Fang, Yuan;
Jiang, Jiacan;
Chen, Huaizhen;
Yang, Bing;
Xu, Xiaomin;
Liu, Guoqiang;
Ling, Chen;
Dong, Zhicheng;
Yang, Cunyi;
Wang, Yingxiang

Publication type:

Article

Strain-Divergent m6A Landscapes Modulate Nipah Virus Replication and METTL3 Inhibition Attenuates Virulence.

Published in:

Viruses (1999-4915), 2025, v. 17, n. 6, p. 831, doi. 10.3390/v17060831

By:

Luo, Ting;
Chen, Zhen;
Zhang, Fang;
Liu, Haibin;
Huang, Fang;
Zhang, Xueyan;
Feng, Jiangpeng;
Ding, Shuang;
Liu, Lishi;
Guan, Wuxiang;
Zeng, Aiping;
Hao, Haojie

Publication type:

Article

Specific Phosphorylation of Histone Demethylase KDM3A Determines Target Gene Expression in Response to Heat Shock.

Published in:

PLoS Biology, 2014, v. 12, n. 12, p. 1, doi. 10.1371/journal.pbio.1002026

By:

Cheng, Mo-bin;
Zhang, Yan;
Cao, Chun-yu;
Zhang, Wei-long;
Zhang, Ye;
Shen, Yu-fei

Publication type:

Article

Lysine demethylase 5B (KDM5B): A key regulator of cancer drug resistance.

Published in:

Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 1, p. 1, doi. 10.1002/jbt.23587

By:

Cao, Yaquan;
Wu, Chunli;
Ma, Liying

Publication type:

Article

Fungal cytochrome P450 sterol 14α-demethylase (CYP51) and azole resistance in plant and human pathogens.

Published in:

Applied Microbiology & Biotechnology, 2012, v. 95, n. 4, p. 825, doi. 10.1007/s00253-012-4195-9

By:

Becher, Rayko;
Wirsel, Stefan

Publication type:

Article

Identification of a novel signature based on RNA methylation-associated anoikis-related genes for predicting prognosis and characterizing immune landscape in colorectal cancer.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-01964-y

By:

Zhu, Liye;
Qiu, Xinze;
Liang, Shengmei;
Huang, Shanpei;
Ning, Qiting;
Chen, Xingmei;
Chen, Ni;
Qin, longjie;
Huang, Jiean;
Liu, Shiquan

Publication type:

Article

Toxic effects of Triclosan on the detoxification system and breeding of Daphnia magna.

Published in:

Ecotoxicology, 2013, v. 22, n. 9, p. 1384, doi. 10.1007/s10646-013-1124-3

By:

Peng, Ying;
Luo, Ying;
Nie, Xiang-Ping;
Liao, Wei;
Yang, Yu-Feng;
Ying, Guang-Guo

Publication type:

Article

NCL1, A Highly Selective Lysine-Specific Demethylase 1 Inhibitor, Suppresses Castration-Resistant Prostate Cancer Growth via Regulation of Apoptosis and Autophagy.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 4, p. 442, doi. 10.3390/jcm8040442

By:

Etani, Toshiki;
Naiki, Taku;
Naiki-Ito, Aya;
Suzuki, Takayoshi;
Iida, Keitaro;
Nozaki, Satoshi;
Kato, Hiroyuki;
Nagayasu, Yuko;
Suzuki, Shugo;
Kawai, Noriyasu;
Yasui, Takahiro;
Takahashi, Satoru

Publication type:

Article

Pharmacological Inhibition of Lysine-Specific Demethylase 1A Reduces Atherosclerotic Lesion Formation in Apolipoprotein E-Deficient Mice by a Mechanism Involving Decreased Oxidative Stress and Inflammation; Potential Implications in Human Atherosclerosis.

Published in:

Antioxidants, 2022, v. 11, n. 12, p. 2382, doi. 10.3390/antiox11122382

By:

Manea, Simona-Adriana;
Vlad, Mihaela-Loredana;
Lazar, Alexandra-Gela;
Muresian, Horia;
Simionescu, Maya;
Manea, Adrian

Publication type:

Article

Promoting axon regeneration by inhibiting RNA N6-methyladenosine demethylase ALKBH5.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.85309

By:

Dong Wang;
Tiemei Zheng;
Songlin Zhou;
Mingwen Liu;
Yaobo Liu;
Xiaosong Gu;
Susu Mao;
Bin Yu

Publication type:

Article

CORRIGENDUM: Drosophila Kdm4 demethylases in histone H3 lysine 9 demethylation and ecdysteroid signalling.

Published in:: 2014
Publication type:: Correction Notice

Drosophila Kdm4 demethylases in histone H3 lysine 9 demethylation and ecdysteroid signaling.

Published in:

Scientific Reports, 2013, p. 1, doi. 10.1038/srep02894

By:

Tsurumi, Amy;
Dutta, Pranabanada;
Shian-Jang Yan;
Robin Sheng;
Willis X. Li

Publication type:

Article

Control of enhancer and promoter activation in the type I interferon response by the histone demethylase Kdm4d/JMJD2d.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1146699

By:

Chandwani, Rohit;
Fang, Terry C.;
Dewell, Scott;
Tarakhovsky, Alexander

Publication type:

Article

Relationship between histone demethylase LSD family and development and prognosis of gastric cancer .

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1170773

By:

Liyan Dong;
Jiaxing Zhu;
Anyi Deng;
Junping Wei;
Jiawei Li;
Xinru Mao;
Zhenghu Jia

Publication type:

Article

Lysine-specific histone demethylase 1 inhibition enhances robust fetal hemoglobin induction in human β0-thalassemia/hemoglobin E erythroid cells.

Published in:

Hematology Reports, 2021, v. 13, n. 4, p. 1, doi. 10.4081/hr.2021.9215

By:

Woratree Kaewsakulthong;
Phitchapa Pongpaksupasin;
Tiwaporn Nualkaew;
Suradej Hongeng;
Suthat Fucharoen;
Natee Jearawiriyapaisarn;
Orapan Sripichai

Publication type:

Article

Temperature-dependent jumonji demethylase modulates flowering time by targeting H3K36me2/3 in Brassica rapa.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-49721-z

By:

Xin, Xiaoyun;
Li, Peirong;
Zhao, Xiuyun;
Yu, Yangjun;
Wang, Weihong;
Jin, Guihua;
Wang, Jiao;
Sun, Liling;
Zhang, Deshuang;
Zhang, Fenglan;
Yu, Shuancang;
Su, Tongbing

Publication type:

Article

m6A demethylase FTO promotes tumor progression via regulation of lipid metabolism in esophageal cancer.

Published in:

Cell & Bioscience, 2022, v. 12, n. 1, p. 1, doi. 10.1186/s13578-022-00798-3

By:

Duan, Xiaoran;
Yang, Li;
Wang, Liuya;
Liu, Qinghua;
Zhang, Kai;
Liu, Shasha;
Liu, Chaojun;
Gao, Qun;
Li, Lifeng;
Qin, Guohui;
Zhang, Yi

Publication type:

Article

Regulation of histone arginine methylation/demethylation by methylase and demethylase.

Published in:

Molecular Medicine Reports, 2019, v. 19, n. 5, p. 3963

By:

Zhang, Jing;
Jing, Li;
Li, Menghan;
He, Lingfeng;
Guo, Zhigang

Publication type:

Article

Lysine-specific demethylase 2 contributes to the proliferation of small cell lung cancer by regulating the expression of TFPI-2.

Published in:

Molecular Medicine Reports, 2018, v. 18, n. 1, p. 733, doi. 10.3892/mmr.2018.9047

By:

Cao, Yunfeng;
Guo, Chunhui;
Yin, Yanhai;
Li, Xin;
Zhou, Ling

Publication type:

Article

Evaluation of Histone Demethylase Inhibitor ML324 and Acyclovir against Cyprinid herpesvirus 3 Infection.

Published in:

Viruses (1999-4915), 2023, v. 15, n. 1, p. 163, doi. 10.3390/v15010163

By:

Matsuoka, Shelby;
Petri, Gloria;
Larson, Kristen;
Behnke, Alexandra;
Wang, Xisheng;
Peng, Muhui;
Spagnoli, Sean;
Lohr, Christiane;
Milston-Clements, Ruth;
Divilov, Konstantin;
Jin, Ling

Publication type:

Article

Ligand-based and structure-based design of novel histone demethylase inhibitors.

Published in:

2013

By:

Carlino, Luca;
Schmitt, Martin Leo;
Jung, Manfred;
Sippl, Wolfgang

Publication type:

Conference Paper/Materials

Abnormal X chromosome inactivation and sex-specific gene dysregulation after ablation of FBXL10.

Published in:

Epigenetics & Chromatin, 2016, v. 9, p. 1, doi. 10.1186/s13072-016-0069-1

By:

Boulard, Mathieu;
Edwards, John R.;
Bestor, Timothy H.

Publication type:

Article

The histone demethylase dKDM5/LID interacts with the SIN3 histone deacetylase complex and shares functional similarities with SIN3.

Published in:

Epigenetics & Chromatin, 2016, v. 9, p. 1, doi. 10.1186/s13072-016-0053-9

By:

Gajan, Ambikai;
Barnes, Valerie L.;
Mengying Liu;
Saha, Nirmalya;
Pile, Lori A.

Publication type:

Article

The Histone Demethylase KDM3B Promotes Osteo-/Odontogenic Differentiation, Cell Proliferation, and Migration Potential of Stem Cells from the Apical Papilla.

Published in:

Stem Cells International, 2020, p. 1, doi. 10.1155/2020/8881021

By:

Zhang, Chen;
Han, Xiao;
Liang, Yuncun;
Liu, Huina;
Fan, Zhipeng;
Zhang, Jianpeng

Publication type:

Article

Histone Demethylase KDM4C Is Required for Ovarian Cancer Stem Cell Maintenance.

Published in:

Stem Cells International, 2020, p. 1, doi. 10.1155/2020/8860185

By:

Chen, Guo-Qing;
Ye, Ping;
Ling, Rong-Song;
Zeng, Fa;
Zhu, Xiong-Shan;
Chen, Lu;
Huang, Yan;
Xu, Ling;
Xie, Xiao-Ying

Publication type:

Article

Comparison of the florfenicol metabolic rate in Portunus trituberculatus individuals with different body weights.

Published in:

Aquaculture Research, 2019, v. 50, n. 3, p. 798, doi. 10.1111/are.13945

By:

Ren, Xianyun;
Gao, Baoquan;
Meng, Xianliang;
Liu, Ping;
Li, Jian

Publication type:

Article

Lysine-Specific Demethylase 1 (LSD1) epigenetically controls osteoblast differentiation.

Published in:

PLoS ONE, 2022, v. 17, n. 3, p. 1, doi. 10.1371/journal.pone.0265027

By:

Rummukainen, Petri;
Tarkkonen, Kati;
Dudakovic, Amel;
Al-Majidi, Rana;
Nieminen-Pihala, Vappu;
Valensisi, Cristina;
Hawkins, R. David;
van Wijnen, Andre J.;
Kiviranta, Riku

Publication type:

Article

Deficiency of N6-Methyladenosine Demethylase ALKBH5 Alleviates Ultraviolet B Radiation-Induced Chronic Actinic Dermatitis via Regulating Pyroptosis.

Published in:

Inflammation, 2024, v. 47, n. 1, p. 159, doi. 10.1007/s10753-023-01901-7

By:

He, Li;
Liu, Lan;
Xu, Dan;
Tu, Ying;
Yang, Chenling;
Zhang, Mei;
Wang, Hongyun;
Nong, Xiang

Publication type:

Article

The role of histone demethylases in cancer therapy

Published in:

Molecular Oncology, 2012, v. 6, n. 6, p. 683, doi. 10.1016/j.molonc.2012.07.004

By:

Hoffmann, Inga;
Roatsch, Martin;
Schmitt, Martin L.;
Carlino, Luca;
Pippel, Martin;
Sippl, Wolfgang;
Jung, Manfred

Publication type:

Article

Lysine-specific demethylase-1 modifies the age effect on blood pressure sensitivity to dietary salt intake.

Published in:

Age (0161-9152), 2013, v. 35, n. 5, p. 1809, doi. 10.1007/s11357-012-9480-0

By:

Krug, Alexander;
Tille, Eric;
Sun, Bei;
Pojoga, Luminita;
Williams, Jonathan;
Chamarthi, Bindu;
Lichtman, Andrew;
Hopkins, Paul;
Adler, Gail;
Williams, Gordon

Publication type:

Article

α-Ketoglutarate-dependent Enzymes in Breast Cancer and Therapeutic Implications.

Published in:

Endocrinology, 2023, v. 164, n. 6, p. 1, doi. 10.1210/endocr/bqad080

By:

Xiong, Jingjing;
Yan, Chaojun;
Zhang, Qing;
Zhang, Jing

Publication type:

Article

Role of JMJD3 in Ovarian Follicular Development.

Published in:

Endocrinology, 2022, v. 163, n. 7, p. 1, doi. 10.1210/endocr/bqac063

By:

Roy, Shyamal K

Publication type:

Article

Control of Breast Cancer Pathogenesis by Histone Methylation and the Hairless Histone Demethylase.

Published in:

Endocrinology, 2021, v. 162, n. 8, p. 1, doi. 10.1210/endocr/bqab088

By:

Trager, Megan H;
Sah, Bindeshwar;
Chen, Zhongming;
Liu, Liang

Publication type:

Article

Expression pattern and regulatory effect of lysine-specific demethylase 2A gene in clear cell renal cell carcinoma.

Published in:

2021

By:

Wang, Jiannan;
Li, Tan;
Li, Xiang;
Zhang, Yixia;
Wang, Xuemei

Publication type:

journal article

Long-term exercise training down-regulates m6A RNA demethylase FTO expression in the hippocampus and hypothalamus: an effective intervention for epigenetic modification.

Published in:

2022

By:

Liu, Shu-Jing;
Cai, Tong-Hui;
Fang, Chun-Lu;
Lin, Shao-Zhang;
Yang, Wen-Qi;
Wei, Yuan;
Zhou, Fu;
Liu, Ling;
Luo, Yuan;
Guo, Zi-Yi;
Zhao, Ge;
Li, Ya-Ping;
Li, Liang-Ming

Publication type:

journal article

Inhibition of the H3K27 demethylase UTX enhances the epigenetic silencing of HIV proviruses and induces HIV-1 DNA hypermethylation but fails to permanently block HIV reactivation.

Published in:

PLoS Pathogens, 2021, v. 17, n. 10, p. 1, doi. 10.1371/journal.ppat.1010014

By:

Nguyen, Kien;
Dobrowolski, Curtis;
Shukla, Meenakshi;
Cho, Won-Kyung;
Luttge, Benjamin;
Karn, Jonathan

Publication type:

Article

Histone demethylase LSD1 promotes RIG-I poly-ubiquitination and anti-viral gene expression.

Published in:

PLoS Pathogens, 2021, v. 17, n. 9, p. 1, doi. 10.1371/journal.ppat.1009918

By:

Hu, Qi-Xin;
Wang, Hui-Yi;
Jiang, Lu;
Wang, Chen-Yu;
Ju, Lin-Gao;
Zhu, Yuan;
Zhong, Bo;
Wu, Min;
Wang, Zhen;
Li, Lian-Yun

Publication type:

Article

Dioxygen Binding Is Controlled by the Protein Environment in Non‐heme FeII and 2‐Oxoglutarate Oxygenases: A Study on Histone Demethylase PHF8 and an Ethylene‐Forming Enzyme.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 24, p. 1, doi. 10.1002/chem.202300138

By:

Chaturvedi, Shobhit S.;
Thomas, Midhun George;
Bathir Jaber Sathik Rifayee, Simahudeen;
White, Walter;
Wildey, Jon;
Warner, Cait;
Schofield, Christopher J.;
Hu, Jian;
Hausinger, Robert P.;
Karabencheva‐Christova, Tatayana G.;
Christov, Christo Z.

Publication type:

Article

Front Cover: Dioxygen Binding Is Controlled by the Protein Environment in Non‐heme FeII and 2‐Oxoglutarate Oxygenases: A Study on Histone Demethylase PHF8 and an Ethylene‐Forming Enzyme (Chem. Eur. J. 24/2023).

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 24, p. 1, doi. 10.1002/chem.202300138

By:

Chaturvedi, Shobhit S.;
Thomas, Midhun George;
Rifayee, Simahudeen Bathir Jaber Sathik;
White, Walter;
Wildey, Jon;
Warner, Cait;
Schofield, Christopher J.;
Hu, Jian;
Hausinger, Robert P.;
Karabencheva‐Christova, Tatayana G.;
Christov, Christo Z.

Publication type:

Article

Dioxygen Binding Is Controlled by the Protein Environment in Non‐heme FeII and 2‐Oxoglutarate Oxygenases: A Study on Histone Demethylase PHF8 and an Ethylene‐Forming Enzyme.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 24, p. 1, doi. 10.1002/chem.202300138

By:

Chaturvedi, Shobhit S.;
Thomas, Midhun George;
Rifayee, Simahudeen Bathir Jaber Sathik;
White, Walter;
Wildey, Jon;
Warner, Cait;
Schofield, Christopher J.;
Hu, Jian;
Hausinger, Robert P.;
Karabencheva‐Christova, Tatayana G.;
Christov, Christo Z.

Publication type:

Article

What Is the Catalytic Mechanism of Enzymatic Histone N‐Methyl Arginine Demethylation and Can It Be Influenced by an External Electric Field?

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 46, p. 11750, doi. 10.1002/chem.202102158

By:

Ramanan, Rajeev;
Waheed, Sodiq O.;
Schofield, Christopher J.;
Christov, Christo Z.

Publication type:

Article

The Molecular Basis of Human ALKBH3 Mediated RNA N1‐methyladenosine (m1A) Demethylation.

Published in:

Angewandte Chemie, 2024, v. 136, n. 7, p. 1, doi. 10.1002/ange.202313900

By:

Zhang, Lin;
Duan, Hong‐Chao;
Paduch, Marcin;
Hu, Jingyan;
Zhang, Chi;
Mu, Yajuan;
Lin, Houwen;
He, Chuan;
Kossiakoff, Anthony A.;
Jia, Guifang;
Zhang, Liang

Publication type:

Article

Frontispiz: Programmable RNA N1‐Methyladenosine Demethylation by a Cas13d‐Directed Demethylase.

Published in:

Angewandte Chemie, 2021, v. 133, n. 36, p. 1, doi. 10.1002/ange.202105253

By:

Xie, Shanshan;
Jin, Hao;
Yang, Feng;
Zheng, Hong;
Chang, Yongxia;
Liao, Ying;
Zhang, Ye;
Zhou, Tianhua;
Li, Yang

Publication type:

Article

Programmable RNA N1‐Methyladenosine Demethylation by a Cas13d‐Directed Demethylase.

Published in:

Angewandte Chemie, 2021, v. 133, n. 36, p. 19744, doi. 10.1002/ange.202105253

By:

Xie, Shanshan;
Jin, Hao;
Yang, Feng;
Zheng, Hong;
Chang, Yongxia;
Liao, Ying;
Zhang, Ye;
Zhou, Tianhua;
Li, Yang

Publication type:

Article

LEAD‐m6A‐seq for Locus‐Specific Detection of N6‐Methyladenosine and Quantification of Differential Methylation.

Published in:

Angewandte Chemie, 2021, v. 133, n. 2, p. 886, doi. 10.1002/ange.202007266

By:

Wang, Yuru;
Zhang, Zijie;
Sepich‐Poore, Caraline;
Zhang, Lisheng;
Xiao, Yu;
He, Chuan

Publication type:

Article

Design, Synthesis and Characterization of Covalent KDM5 Inhibitors.

Published in:

Angewandte Chemie, 2019, v. 131, n. 2, p. 525, doi. 10.1002/ange.201810179

By:

Vazquez‐Rodriguez, Saleta;
Wright, Miranda;
Rogers, Catherine M.;
Cribbs, Adam P.;
Velupillai, Srikannathasan;
Philpott, Martin;
Lee, Henry;
Dunford, James E.;
Huber, Kilian V. M.;
Robers, Matthew B.;
Vasta, James D.;
Thezenas, Marie‐Laetitia;
Bonham, Sarah;
Kessler, Benedikt;
Bennett, James;
Fedorov, Oleg;
Raynaud, Florence;
Donovan, Adam;
Blagg, Julian;
Bavetsias, Vassilios

Publication type:

Article

EnMCB: an R/bioconductor package for predicting disease progression based on methylation correlated blocks using ensemble models.

Published in:

Bioinformatics, 2021, v. 37, n. 22, p. 4282, doi. 10.1093/bioinformatics/btab415

By:

Yu, Xin;
Kong, De-Xin

Publication type:

Article

Lysine-Specific Histone Demethylase 1 Promotes Oncogenesis of the Esophageal Squamous Cell Carcinoma by Upregulating DUSP4.

Published in:

Biochemistry (00062979), 2021, v. 86, n. 12/13, p. 1624, doi. 10.1134/S0006297921120117

By:

Han, Junyong;
Ye, Shixin;
Chen, Jinyan;
Wang, Kun;
Jin, Jingjun;
Zeng, Zhiyong;
Xue, Shijie

Publication type:

Article

The Role of Lysine-Specific Demethylase 1 (LSD1) in Shaping the Endothelial Inflammatory Response.

Published in:

Cellular Physiology & Biochemistry (Cell Physiol Biochem Press GmbH & Co. KG), 2021, v. 55, n. 5, p. 569, doi. 10.33594/000000436

By:

Wojtala, Martyna;
Rybaczek, Dorota;
Wielgus, Ewelina;
Sobalska-Kwapis, Marta;
Strapagiel, Dominik;
Balcerczyk, Aneta

Publication type:

Article