Works matching DE "DEACETYLASES"

Results: 657

The nucleosome remodeling and deacetylase-SWItch/sucrose non-fermentable antagonism regulates the coordinated activation of epithelial-to-mesenchymal transition and inflammation in oral cancer Open Access.

Published in:

JNCI: Journal of the National Cancer Institute, 2025, v. 117, n. 7, p. 1438, doi. 10.1093/jnci/djaf065

By:

Stabile, Roberto;
Tucci, Francesco A;
Verhagen, Mathijs P;
Embregts, Carmen;
Bosch, Thierry P P van den;
Joosten, Rosalie;
Herdt, Maria J De;
van der Steen, Berdine;
Nigg, Alex L;
Koljenović, Senada;
Hardillo, Jose A;
Verrijzer, Cornelis Peter;
Biddle, Adrian;
Jong, Robert J Baatenburg de;
Leenen, Pieter J M;
Fodde, Riccardo

Publication type:

Article

Bacterial pathogenesis: InlB uses SIRT2 to go nuclear.

Published in:

Nature Reviews Microbiology, 2013, v. 11, n. 9, p. 596, doi. 10.1038/nrmicro3105

By:

Hofer, Ursula

Publication type:

Article

Versatile role of sirtuins in metabolic disorders: From modulation of mitochondrial function to therapeutic interventions.

Published in:

Journal of Biochemical & Molecular Toxicology, 2022, v. 36, n. 7, p. 1, doi. 10.1002/jbt.23047

By:

Afzaal, Ammara;
Rehman, Kanwal;
Kamal, Shagufta;
Akash, Muhammad Sajid Hamid

Publication type:

Article

Inhibition of histone deacetylases is the major pathway mediated by astaxanthin to antagonize LPS‐induced inflammatory responses in mammary epithelial cells.

Published in:

Journal of Biochemical & Molecular Toxicology, 2020, v. 34, n. 8, p. 1, doi. 10.1002/jbt.22507

By:

Venkidasamy, Baskar;
Thiruvengadam, Muthu;
Thirupathi, Prabhu;
Subramanian, Umadevi

Publication type:

Article

Histones on fire: the effect of Dun1 and Mrc1 on origin firing and replication of hyper-acetylated genomes.

Published in:

Current Genetics, 2021, v. 67, n. 4, p. 501, doi. 10.1007/s00294-021-01175-2

By:

Gershon, Lihi;
Kupiec, Martin

Publication type:

Article

A unique CE16 acetyl esterase from Podospora anserina active on polymeric xylan.

Published in:

Applied Microbiology & Biotechnology, 2015, v. 99, n. 24, p. 10515, doi. 10.1007/s00253-015-6934-1

By:

Puchart, Vladimír;
Berrin, Jean-Guy;
Haon, Mireille;
Biely, Peter

Publication type:

Article

Redistribution of acetyl groups on the non-reducing end xylopyranosyl residues and their removal by xylan deacetylases.

Published in:

Applied Microbiology & Biotechnology, 2015, v. 99, n. 9, p. 3865, doi. 10.1007/s00253-014-6160-2

By:

Puchart, Vladimír;
Biely, Peter

Publication type:

Article

Generation and characterization of a site-specific antibody for SIRT1 O-GlcNAcylated at serine 549.

Published in:

Glycobiology, 2018, v. 28, n. 7, p. 482, doi. 10.1093/glycob/cwy040

By:

Hui Shan;
Jiahui Sun;
Minghui Shi;
Xue Liu;
Zhu Shi;
Wengong Yu;
Yuchao Gu

Publication type:

Article

Machine Learning Approaches to Predict the Selectivity of Compounds against HDAC1 and HDAC6.

Published in:

Journal of Computational Biophysics & Chemistry, 2024, v. 23, n. 6, p. 837, doi. 10.1142/S2737416524500121

By:

Dogan, Berna

Publication type:

Article

Pharmacophore-based Virtual Screening: Identification of Selective Sirtuin 2 Inhibitors.

Published in:

Journal of Research in Pharmacy, 2023, v. 27, n. 4, p. 1366, doi. 10.29228/jrp.424

By:

KARAMAN MAYACK, Berin;
ALAYOUBI, Muhammed Moyasar

Publication type:

Article

组蛋白去乙酰化酶 CfSnt2 调控果生刺盘孢生长发育和致病力.

Published in:

Mycosystema, 2022, v. 41, n. 6, p. 926, doi. 10.13346/j.mycosystema.210364

By:

陈振宏;
李河;
陈嘉怡;
陈晓迪;
罗晶;
张盛培

Publication type:

Article

SIRT3 Weighs Heavily in the Metabolic Balance: A New Role for SIRT3 in Metabolic Syndrome.

Published in:

Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2013, v. 68, n. 2, p. 105, doi. 10.1093/gerona/gls132

By:

Green, Michelle F.;
Hirschey, Matthew D.

Publication type:

Article

Metal-binding effects of sirtuin inhibitor sirtinol.

Published in:

Supramolecular Chemistry, 2016, v. 28, n. 1/2, p. 108, doi. 10.1080/10610278.2015.1092537

By:

Akam, Eman A.;
Gautam, Ritika;
Tomat, Elisa

Publication type:

Article

Histone Deacetylases and Their Inhibitors in Cancer Epigenetics.

Published in:

Diseases, 2019, v. 7, n. 4, p. 57, doi. 10.3390/diseases7040057

By:

Hassell, Kelly N.

Publication type:

Article

High levels of SIRT1 expression enhance tumorigenesis and associate with a poor prognosis of colorectal carcinoma patients.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep07481

By:

Xiaojing Chen;
Kai Sun;
Shufan Jiao;
Ning Cai;
Xue Zhao;
Hanbing Zou;
Yuexia Xie;
Zhengshi Wang;
Ming Zhong;
Lixin Wei

Publication type:

Article

Rational design and validation of a Tip60 histone acetyltransferase inhibitor.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep05372

By:

Gao, Chunxia;
Bourke, Emer;
Scobie, Martin;
Famme, Melina Arcos;
Koolmeister, Tobias;
Helleday, Thomas;
Eriksson, Leif A.;
Lowndes, Noel F.;
Brown, James A. L.

Publication type:

Article

Metabolic Characterization of a Sirt5 deficient mouse model.

Published in:

Scientific Reports, 2013, p. 1, doi. 10.1038/srep02806

By:

Jiujiu Yu;
Sadhukhan, Sushabhan;
Noriega, Lilia G.;
Moullan, Norman;
He, Bin;
Weiss, Robert S.;
Hening Lin;
Schoonjans, Kristina;
Auwerx, Johan

Publication type:

Article

A novel c.-274C>G polymorphism in bovine SIRT1 gene contributes to diminished promoter activity and is associated with increased body size.

Published in:

Animal Genetics, 2013, v. 44, n. 5, p. 584, doi. 10.1111/age.12048

By:

Li, Ming‐xun;
Sun, Xiao‐mei;
Zhang, Liang‐zhi;
Wang, Jing;
Huang, Yong‐zhen;
Sun, Yu‐jia;
Hu, Shen‐rong;
Lan, Xian‐yong;
Lei, Chu‐zhao;
Chen, Hong

Publication type:

Article

Inhibition of histone deacetylases attenuates tumor progression and improves immunotherapy in breast cancer.

Published in:

Frontiers in Immunology, 2023, v. 14, p. 1, doi. 10.3389/fimmu.2023.1164514

By:

Bi Lian;
Xiaosong Chen;
Kunwei Shen

Publication type:

Article

Synergistic Enhancement of Cancer Therapy Using HDAC Inhibitors: Opportunity for Clinical Trials.

Published in:

Frontiers in Genetics, 2020, v. 11, p. N.PAG, doi. 10.3389/fgene.2020.578011

By:

Hontecillas-Prieto, Lourdes;
Flores-Campos, Rocío;
Silver, Andrew;
de Álava, Enrique;
Hajji, Nabil;
García-Domínguez, Daniel J.

Publication type:

Article

Effect of Nasal CPAP on SIRT1 and Endothelial Function in Obstructive Sleep Apnea Syndrome.

Published in:

Lung (0341-2040), 2015, v. 193, n. 6, p. 1037, doi. 10.1007/s00408-015-9790-y

By:

Chen, Wei-Ji;
Liaw, Shwu-Fang;
Lin, Ching-Chi;
Chiu, Chung-Hsin;
Lin, Mei-Wei;
Chang, Feng-Ting

Publication type:

Article

Isotype-Specific Inhibition of Histone Deacetylases: Identification of Optimal Targets for Radiosensitization.

Published in:

Cancer Research & Treatment, 2016, v. 48, n. 3, p. 1130, doi. 10.4143/crt.2015.206

By:

Jin Ho Kim;
Sung Ho Moon;
Mina No;
Jae Jin Kim;
Eun Jung Choi;
Bong Jun Cho;
Jae Sung Kim;
Il Han Kim;
In Ah Kim

Publication type:

Article

RASSF1A Suppresses Cell Migration through Inactivation of HDAC6 and Increase of Acetylated a-Tubulin.

Published in:

Cancer Research & Treatment, 2013, v. 45, n. 2, p. 134, doi. 10.4143/crt.2013.45.2.134

By:

Hae-Yun Jung;
Jun Seok Jung;
Young Mi Whang;
Yeul Hong Kim

Publication type:

Article

Discovery of Potent and Isoform‐selective Histone Deacetylase Inhibitors Using Structure‐based Virtual Screening and Biological Evaluation.

Published in:

Molecular Informatics, 2022, v. 41, n. 9, p. 1, doi. 10.1002/minf.202100295

By:

Peng, Zhe;
Zhao, Quanfeng;
Tian, Xiaoyan;
Lei, Tiantian;
Xiang, Rongfeng;
Chen, Lin;
Yang, Yang

Publication type:

Article

Histone deacetylases regulate organ-specific growth in a horned beetle.

Published in:

EvoDevo, 2024, v. 15, n. 1, p. 1, doi. 10.1186/s13227-024-00223-5

By:

Hu, Yonggang;
Crabtree, Jordan R.;
Macagno, Anna L. M.;
Moczek, Armin P.

Publication type:

Article

Research progress in the regulatory mechanism of silent information regulator 1 in sepsis (Review).

Published in:

Molecular Medicine Reports, 2025, v. 32, n. 2, p. N.PAG, doi. 10.3892/mmr.2025.13573

By:

Zhou, Qilong;
Gao, Weijie;
Zhang, Weijin;
Tang, Shu;
Fu, Hongxue;
Pan, Pengfei

Publication type:

Article

NLRP3/IL1β inflammasome associated with the aging bladder triggers bladder dysfunction in female rats.

Published in:

Molecular Medicine Reports, 2019, v. 19, n. 4, p. 2960

By:

Chen, Lin;
He, Ping-Lin;
Yang, Jin;
Yang, Ya-Fei;
Wang, Kai;
Amend, Bastian;
Stenzl, Arnulf;
Zhang, Ya-Mei;
Wang, Zi-Li;
Xing, Sha-Sha;
Luo, Xu

Publication type:

Article

Role of histone deacetylase expression levels and activity in the inflammatory responses of patients with chronic hepatitis B.

Published in:

Molecular Medicine Reports, 2017, v. 15, n. 5, p. 2744, doi. 10.3892/mmr.2017.6290

By:

HAIYUE ZHANG;
XUN LI;
QIAN ZHANG;
FAN YANG;
XIAOGANG CHU;
DI ZHANG;
LUWEN WANG;
ZUOJIONG GONG

Publication type:

Article

Involvement of retinoblastoma-associated protein 48 during photodynamic therapy of cervical cancer cells.

Published in:

Molecular Medicine Reports, 2017, v. 15, n. 3, p. 1393, doi. 10.3892/mmr.2017.6151

By:

SHUXIA WU;
LIJUN WANG;
XINGYE REN;
YULU PAN;
YAN PENG;
XIAOYAN ZOU;
CUIGE SHI;
YOUZHONG ZHANG

Publication type:

Article

Emodin suppresses silica-induced lung fibrosis by promoting Sirt1 signaling via direct contact.

Published in:

Molecular Medicine Reports, 2016, v. 14, n. 5, p. 4643, doi. 10.3892/mmr.2016.5838

By:

TIAN YANG;
JINYUAN WANG;
YAMEI PANG;
XIAOMIN DANG;
HUI REN;
YA LIU;
MINGWEI CHEN;
DONG SHANG

Publication type:

Article

Trichostatin A increases the TIMP-1/MMP ratio to protect against osteoarthritis in an animal model of the disease.

Published in:

Molecular Medicine Reports, 2016, v. 14, n. 3, p. 2423, doi. 10.3892/mmr.2016.5523

By:

HAO QU;
JIN LI;
LI-DONG WU;
WEI-PING CHEN

Publication type:

Article

Protective effects of icariin-mediated SIRT1/FOXO3 signaling pathway on intestinal ischemia/reperfusion-induced acute lung injury.

Published in:

Molecular Medicine Reports, 2015, v. 11, n. 1, p. 269, doi. 10.3892/mmr.2014.2679

By:

FENG ZHANG;
ZHEN-LU LI;
XIAO-MEI XU;
YAN HU;
JI-HONG YAO;
WEI XU;
HUI-RONG JING;
SHU WANG;
SHI-LI NING;
XIAO-FENG TIAN

Publication type:

Article

Sirt6 suppresses hepatocellular carcinoma cell growth via inhibiting the extracellular signal-regulated kinase signaling pathway.

Published in:

Molecular Medicine Reports, 2014, v. 9, n. 3, p. 882, doi. 10.3892/mmr.2013.1879

By:

ZHI-GAO ZHANG;
CHENG-YONG QIN

Publication type:

Article

A Deacetylase Cq SIRT1 Promotes WSSV Infection by Binding to Viral Envelope Proteins in Cherax quadricarinatus.

Published in:

Viruses (1999-4915), 2022, v. 14, n. 8, p. 1733, doi. 10.3390/v14081733

By:

Zheng, Shucheng;
Meng, Fanjuan;
Li, Dongli;
Liu, Lingke;
Ge, Di;
Wang, Qing;
Liu, Haipeng

Publication type:

Article

Histone chaperones and the Rrm3p helicase regulate flocculation in S. cerevisiae.

Published in:

Epigenetics & Chromatin, 2019, v. 12, n. 1, p. N.PAG, doi. 10.1186/s13072-019-0303-8

By:

Rowlands, Hollie;
Shaban, Kholoud;
Foster, Barret;
Proteau, Yannic;
Yankulov, Krassimir

Publication type:

Article

Fine-tuning of chromatin composition and Polycomb recruitment by two Mi2 homologues during C. elegans early embryonic development.

Published in:

Epigenetics & Chromatin, 2016, v. 8, p. 1, doi. 10.1186/s13072-016-0091-3

By:

Käser-Pébernard, Stéphanie;
Pfefferli, Catherine;
Aschinger, Caroline;
Wicky, Chantal

Publication type:

Article

ZBTB33 binds unmethylated regions of the genome associated with actively expressed genes.

Published in:

Epigenetics & Chromatin, 2013, v. 6, n. 1, p. 1, doi. 10.1186/1756-8935-6-13

By:

Blattler, Adam;
Lijing Yao;
Yao Wang;
Zhenqing Ye;
Jin, Victor X.;
Farnham, Peggy J.

Publication type:

Article

Chromatin reassembly following RNA polymerase II transcription.

Published in:

2013

By:

Venkatesh, Swaminathan;
Smolle, Michaela;
Hua Li;
Gogol, Madelaine;
Ying Zhang;
Laurens, Florence;
Washburn, Michael P.;
Workman, Jerry L.

Publication type:

Conference Paper/Materials

Histone deacetylase inhibitor potentiated the ability of MTOR inhibitor to induce autophagic cell death in Burkitt leukemia/lymphoma.

Published in:

Journal of Hematology & Oncology, 2013, v. 6, n. 1, p. 1, doi. 10.1186/1756-8722-6-53

By:

Li Hua Dong;
Shu Cheng;
Zhong Zheng;
Li Wang;
Yang Shen;
Zhi Xiang Shen;
Sai Juan Chen;
Wei Li Zhao

Publication type:

Article

Novel dual LSD1/HDAC6 inhibitor for the treatment of cancer.

Published in:

PLoS ONE, 2023, v. 18, n. 1, p. 1, doi. 10.1371/journal.pone.0279063

By:

Gajendran, Chandru;
Tantry, Subramanyam Janardhan;
M., Naveen Sadhu;
Mohammed, Zainuddin;
Dewang, Purushottam;
Hallur, Mahanandeesha;
Nair, Sreekala;
Vaithilingam, Krishnakumar;
Nagayya, Basavaprabhu;
Rajagopal, Sridharan;
Sivanandhan, Dhanalakshmi

Publication type:

Article

Sirtuin 2 (SIRT2): Confusing Roles in the Pathophysiology of Neurological Disorders.

Published in:

Frontiers in Neuroscience, 2021, v. 15, p. 1, doi. 10.3389/fnins.2021.614107

By:

Chen, Xiuqi;
Lu, Wenmei;
Wu, Danhong

Publication type:

Article

Modulation of human longevity by SIRT3 single nucleotide polymorphisms in the prospective study 'Treviso Longeva (TRELONG)'.

Published in:

Age (0161-9152), 2014, v. 36, n. 1, p. 469, doi. 10.1007/s11357-013-9559-2

By:

Albani, Diego;
Ateri, Eleonora;
Mazzuco, Stefano;
Ghilardi, Alice;
Rodilossi, Serena;
Biella, Gloria;
Ongaro, Fausta;
Antuono, Piero;
Boldrini, Paolo;
Giorgi, Enrico;
Frigato, Andrea;
Durante, Elisabetta;
Caberlotto, Livio;
Zanardo, Andrea;
Siculi, Marinella;
Gallucci, Maurizio;
Forloni, Gianluigi

Publication type:

Article

SIRT1 inhibits apoptosis of degenerative human disc nucleus pulposus cells through activation of Akt pathway.

Published in:

Age (0161-9152), 2013, v. 35, n. 5, p. 1741, doi. 10.1007/s11357-012-9474-y

By:

Wang, DaWu;
Hu, ZhenMing;
Hao, Jie;
He, Bin;
Gan, Qiang;
Zhong, XiaoMing;
Zhang, XiaoJun;
Shen, JieLiang;
Fang, Ji;
Jiang, Wei

Publication type:

Article

Antagonism between granulocytic maturation and deacetylase inhibitor-induced apoptosis in acute promyelocytic leukaemia cells.

Published in:

British Journal of Cancer, 2015, v. 112, n. 2, p. 329, doi. 10.1038/bjc.2014.589

By:

Hennig, D;
Müller, S;
Wichmann, C;
Drube, S;
Pietschmann, K;
Pelzl, L;
Grez, M;
Bug, G;
Heinzel, T;
Krämer, O H

Publication type:

Article

Phase I study of panobinostat and imatinib in patients with treatment-refractory metastatic gastrointestinal stromal tumors.

Published in:

British Journal of Cancer, 2014, v. 110, n. 5, p. 1155, doi. 10.1038/bjc.2013.826

By:

Bauer, S;
Hilger, R A;
Mühlenberg, T;
Grabellus, F;
Nagarajah, J;
Hoiczyk, M;
Reichardt, A;
Ahrens, M;
Reichardt, P;
Grunewald, S;
Scheulen, M E;
Pustowka, A;
Bock, E;
Schuler, M;
Pink, D

Publication type:

Article

Fulvestrant induces resistance by modulating GPER and CDK6 expression: implication of methyltransferases, deacetylases and the hSWI/SNF chromatin remodelling complex.

Published in:

British Journal of Cancer, 2013, v. 109, n. 10, p. 2751, doi. 10.1038/bjc.2013.583

By:

Giessrigl, B;
Schmidt, W M;
Kalipciyan, M;
Jeitler, M;
Bilban, M;
Gollinger, M;
Krieger, S;
Jäger, W;
Mader, R M;
Krupitza, G

Publication type:

Article

Sirtuins and renal diseases: relationship with aging and diabetic nephropathy.

Published in:

Clinical Science, 2013, v. 124, n. 3, p. 153, doi. 10.1042/CS20120190

By:

KITADA, Munehiro;
KUME, Shinji;
TAKEDA-WATANABE, Ai;
KANASAKI, Keizo;
KOYA, Daisuke

Publication type:

Article

Expression of SIRT1 in Gastric Cardiac Cancer and Its Clinicopathologic Significance.

Published in:

International Journal of Surgical Pathology, 2011, v. 19, n. 6, p. 743, doi. 10.1177/1066896911412181

By:

Feng, An Ning;
Zhang, Li Hua;
Fan, Xiang Shan;
Huang, Qin;
Ye, Qing;
Wu, Hong Yan;
Yang, Jun

Publication type:

Article

Tryptophan metabolite norharman secreted by cultivated Lactobacillus attenuates acute pancreatitis as an antagonist of histone deacetylases.

Published in:

BMC Medicine, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12916-023-02997-2

By:

Zhou, Qi;
Tao, Xufeng;
Guo, Fangyue;
Wu, Yu;
Deng, Dawei;
Lv, Linlin;
Dong, Deshi;
Shang, Dong;
Xiang, Hong

Publication type:

Article

Opening the Selectivity Pocket in the Human Lysine Deacetylase Sirtuin2 – New Opportunities, New Questions.

Published in:

Chemical Record, 2018, v. 18, n. 12, p. 1701, doi. 10.1002/tcr.201800044

By:

Robaa, Dina;
Monaldi, Daria;
Wössner, Nathalie;
Kudo, Norio;
Rumpf, Tobias;
Schiedel, Matthias;
Yoshida, Minoru;
Jung, Manfred

Publication type:

Article