Works matching DE "CYTOSINE deaminase"

Results: 71

Elimination of the nptII marker gene in transgenic apple and pear with a chemically inducible R/Rs recombinase.

Published in:

Plant Cell, Tissue & Organ Culture, 2014, v. 117, n. 3, p. 335, doi. 10.1007/s11240-014-0443-2

By:

Righetti, L.;
Djennane, S.;
Berthelot, P.;
Cournol, R.;
Wilmot, N.;
Loridon, K.;
Vergne, E.;
Chevreau, E.

Publication type:

Article

Increased sensitivity of glioma cells to 5-fluorocytosine following photo-chemical internalization enhanced nonviral transfection of the cytosine deaminase suicide gene.

Published in:

Journal of Neuro-Oncology, 2014, v. 118, n. 1, p. 29, doi. 10.1007/s11060-014-1410-9

By:

Wang, Frederick;
Zamora, Genesis;
Sun, Chung-Ho;
Trinidad, Anthony;
Chun, Changho;
Kwon, Young;
Berg, Kristian;
Madsen, Steen;
Hirschberg, Henry

Publication type:

Article

Double suicide gene therapy using human neural stem cells against glioblastoma: double safety measures.

Published in:

Journal of Neuro-Oncology, 2014, v. 116, n. 1, p. 49, doi. 10.1007/s11060-013-1264-6

By:

Lee, Ji;
Lee, Do-Hun;
Kim, Hyung;
Choi, Seung-Ah;
Lee, Hong;
Park, Chul-Kee;
Phi, Ji;
Wang, Kyu-Chang;
Kim, Seung;
Kim, Seung-Ki

Publication type:

Article

Genomic methylation patterns in archaeological barley show de-methylation as a time-dependent diagenetic process.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep05559

By:

Smith, Oliver;
Clapham, Alan J.;
Rose, Pam;
Yuan Liu;
Jun Wang;
Allaby, Robin G.

Publication type:

Article

Huntington’s Disease in a Patient Misdiagnosed as Conversion Disorder.

Published in:

Case Reports in Psychiatry, 2018, p. 1, doi. 10.1155/2018/3915657

By:

Nogueira, João Machado;
Franco, Ana Margarida;
Mendes, Susana;
Valadas, Anabela;
Semedo, Cristina;
Jesus, Gustavo

Publication type:

Article

Targeted endostatin-cytosine deaminase fusion gene therapy plus 5-fluorocytosine suppresses ovarian tumor growth.

Published in:

Oncogene, 2013, v. 32, n. 9, p. 1082, doi. 10.1038/onc.2012.134

By:

Sher, Y-P;
Chang, C-M;
Juo, C-G;
Chen, C-T;
Hsu, J L;
Lin, C-Y;
Han, Z;
Shiah, S-G;
Hung, M-C

Publication type:

Article

Anti-proliferative Effect of Engineered Neural Stem Cells Expressing Cytosine Deaminase and Interferon-β against Lymph Node-Derived Metastatic Colorectal Adenocarcinoma in Cellular and Xenograft Mouse Models.

Published in:

Cancer Research & Treatment, 2017, v. 49, n. 1, p. 79, doi. 10.4143/crt.2015.503

By:

Geon-Tae Park;
Kim, Seung U.;
Kyung-Chul Choi

Publication type:

Article

Effect of alginate microencapsulation on the catalytic efficiency and in vitro enzyme-prodrug therapeutic efficacy of cytosine deaminase and of recombinant E. coli expressing cytosine deaminase.

Published in:

Journal of Microencapsulation, 2016, v. 33, n. 1, p. 64, doi. 10.3109/02652048.2015.1115902

By:

Funaro, Michael G.;
Nemani, Krishnamurthy V.;
Chen, Zhihang;
Bhujwalla, Zaver M.;
Griswold, Karl E.;
Gimi, Barjor

Publication type:

Article

Cloning, Characterization and Bioinformatics Analysis of Novel Cytosine Deaminase from Escherichia coli AGH09.

Published in:

International Journal of Peptide Research & Therapeutics, 2015, v. 21, n. 3, p. 365, doi. 10.1007/s10989-015-9465-9

By:

Gholami, Ahmad;
Shahin, Samaneh;
Mohkam, Milad;
Nezafat, Navid;
Ghasemi, Younes

Publication type:

Article

Effects of prostaglandin E<sub>2</sub> on p53 mRNA transcription and p53 mutagenesis during T-cell-independent human B-cell clonal expansion.

Published in:

FASEB Journal, 2014, v. 28, n. 2, p. 627, doi. 10.1096/fj.13-237792

By:

Haque, Shabirul;
Xiao Jie Yan;
Rosen, Lisa;
McCormick, Steven;
Chiorazzi, Nicholas;
Mongini, Patricia K. A.

Publication type:

Article

C/EBPβ LIP induces a tumor menagerie making it an oncogene.

Published in:

2015

By:

Luft, Friedrich

Publication type:

Editorial

Mesenchymal stem cells expressing cytosine deaminase inhibit growth of murine melanoma B16F10 in vivo.

Published in:

Molecular Biology, 2015, v. 49, n. 6, p. 904, doi. 10.1134/S0026893315060126

By:

Krasikova, L.;
Karshieva, S.;
Cheglakov, I.;
Belyavsky, A.

Publication type:

Article

PC3 - 151 Toca 5: A Phase 2/3 Randomized, Open-Label Study of Toca 511, a Retroviral Replicating Vector, Combined with Toca FC versus Standard of Care in Patients Undergoing Planned Resection for Recurrent Glioblastoma (GBM) or Anaplastic Astrocytoma ...

Published in:

Canadian Journal of Neurological Sciences, 2016, v. 43, p. S17, doi. 10.1017/cjn.2016.379

By:

Zadeh, G.;
Bota, D.;
Cachia, D.;
Landolfi, J.;
Schiff, D.;
Vogelbaum, M.A.;
Walbert, T.;
Tran, D.;
Chu, A.;
Das, A.;
Jolly, D.J.;
Ibañez, C.E.;
Ostertag, D.;
Sully, S.;
Cloughesy, T.F.

Publication type:

Article

OS8 - 150 Encouraging Survival with Toca 511 and Toca FC Compared to External Lomustine Control.

Published in:

Canadian Journal of Neurological Sciences, 2016, v. 43, p. S4, doi. 10.1017/cjn.2016.339

By:

Huang, T.T;
Aghi, M.K;
Chen, C.C;
Elder, J.B;
Kesari, S;
Kalkanis, S;
Kaptain, G;
Landolfi, J;
Mikkelsen, T;
Portnow, J;
Robbins, J.M;
Ostertag, D;
Das, A;
Chu, A;
Vogelbaum, M.A

Publication type:

Article

Phase 1 trial of vocimagene amiretrorepvec and 5-fluorocytosine for recurrent high-grade glioma.

Published in:

Science Translational Medicine, 2016, v. 8, n. 341, p. 1, doi. 10.1126/scitranslmed.aad9784

By:

Cloughesy, Timothy F.;
Landolfi, Joseph;
Hogan, Daniel J.;
Bloomfield, Stephen;
Carter, Bob;
Chen, Clark C.;
Elder, J. Bradley;
Kalkanis, Steven N.;
Kesari, Santosh;
Lai, Albert;
Lee, Ian Y.;
Liau, Linda M.;
Mikkelsen, Tom;
Nghiemphu, Phioanh Leia;
Piccioni, David;
Walbert, Tobias;
Chu, Alice;
Das, Asha;
Diago, Oscar R.;
Gammon, Dawn

Publication type:

Article

Migration to gliomas of bone mesenchymal stem cells transfected with cytosine deaminase gene following transplantation in vivo.

Published in:

Neural Regeneration Research, 2011, v. 6, n. 19, p. 1462, doi. 10.3969/j.issn.1673-5374.2011.19.004

By:

Guangchun Ji;
Fei Song;
Qi Xing;
Jian Liu;
Kedong Song;
Daqing Zhang;
Zihan Wang

Publication type:

Article

Inhibitory effects of cytosine deaminase gene-transfected bone marrow mesenchymal stem cells on glioma cell proliferation.

Published in:

Neural Regeneration Research, 2011, v. 6, n. 16, p. 1238, doi. 10.3969/j.issn.1673-5374.2011.16.007

By:

Fei Song;
Qi Xing;
Kedong Song;
Jian Liu;
Guangchun Ji;
Yufang Ma;
Tianqing Liu;
Minghai Wei;
Xuehu Ma

Publication type:

Article

A bacterial gene codA encoding cytosine deaminase is an effective conditional negative selectable marker in Glycine max.

Published in:

Plant Cell Reports, 2015, v. 34, n. 10, p. 1707, doi. 10.1007/s00299-015-1818-5

By:

Shao, Min;
Michno, Jean-Michel;
Hotton, Sara;
Blechl, Ann;
Thomson, James

Publication type:

Article

Genetically Engineered Microvesicles Carrying Suicide mRNA/Protein Inhibit Schwannoma Tumor Growth.

Published in:

Molecular Therapy, 2013, v. 21, n. 1, p. 101, doi. 10.1038/mt.2012.161

By:

Mizrak, Arda;
Bolukbasi, Mehmet Fatih;
Ozdener, Gokhan Baris;
Brenner, Gary J;
Madlener, Sibylle;
Erkan, Erdogan Pekcan;
Ströbel, Thomas;
Breakefield, Xandra O;
Saydam, Okay

Publication type:

Article

Design and Selection of Toca 511 for Clinical Use: Modified Retroviral Replicating Vector With Improved Stability and Gene Expression.

Published in:

Molecular Therapy, 2012, v. 20, n. 9, p. 1689, doi. 10.1038/mt.2012.83

By:

Perez, Omar D;
Logg, Christopher R;
Hiraoka, Kei;
Diago, Oscar;
Burnett, Ryan;
Inagaki, Akihito;
Jolson, Dawn;
Amundson, Karin;
Buckley, Taylor;
Lohse, Dan;
Lin, Amy;
Burrascano, Cindy;
Ibanez, Carlos;
Kasahara, Noriyuki;
Gruber, Harry E;
Jolly, Douglas J

Publication type:

Article

Stabilization of Aspergillus parasiticus cytosine deaminase by immobilization on calcium alginate beads improved enzyme operational stability.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2013, v. 28, n. 6, p. 1217, doi. 10.3109/14756366.2012.724406

By:

Zanna, H.;
Nok, A. J.;
Ibrahim, S.;
Inuwa, H. M.

Publication type:

Article

Molecular mechanism and clinical impact of APOBEC3B-catalyzed mutagenesis in breast cancer.

Published in:

Breast Cancer Research, 2015, v. 17, n. 1, p. 1, doi. 10.1186/s13058-014-0498-3

By:

Harris, Reuben S.

Publication type:

Article

Molecular mechanism and clinical impact of APOBEC3B-catalyzed mutagenesis in breast cancer.

Published in:

Breast Cancer Research, 2015, v. 17, n. 1, p. 1, doi. 10.1186/s13058-014-0498-3

By:

Harris, Reuben S.

Publication type:

Article

Cytosine Deamination Is a Major Cause of Baseline Noise in Next-Generation Sequencing.

Published in:

Molecular Diagnosis & Therapy, 2014, v. 18, n. 5, p. 587, doi. 10.1007/s40291-014-0115-2

By:

Chen, Guoli;
Mosier, Stacy;
Gocke, Christopher;
Lin, Ming-Tseh;
Eshleman, James

Publication type:

Article

Beyond CRISPR: single base editors for human health and crop improvement.

Published in:

Current Science (00113891), 2019, v. 116, n. 3, p. 386, doi. 10.18520/cs/v116/i3/386-397

By:

Gupta, P. K.

Publication type:

Article

Cytotoxic effect of co-expression of human hepatitis A virus 3C protease and bifunctional suicide protein FCU1 genes in a bicistronic vector.

Published in:

Molecular Biology Reports, 2017, v. 44, n. 4, p. 323, doi. 10.1007/s11033-017-4113-4

By:

Komissarov, Alexey;
Demidyuk, Ilya;
Safina, Dina;
Roschina, Marina;
Shubin, Andrey;
Lunina, Nataliya;
Karaseva, Maria;
Kostrov, Sergey

Publication type:

Article

Accumulation of AID in immunoglobulin variable genes in the absence of Topoisomerase I.

Published in:

Turkish Journal of Immunology, 2016, v. 4, p. 22

By:

Saribasak, Huseyin;
Maul, Robert W.;
Cao, Zheng;
Gearhart, Patricia J.

Publication type:

Article

Antiproliferative effect of double suicide gene delivery mediated by polyamidoamine dendrimers in human Tenon's capsule fibroblasts.

Published in:

Experimental & Therapeutic Medicine, 2017, v. 14, n. 6, p. 5473, doi. 10.3892/etm.2017.5235

By:

JIN YANG;
LIU KUN SHI;
HUI MIN SUN;
YAN MING WANG

Publication type:

Article

Crystal structure of mimivirus uracil-DNA glycosylase.

Published in:

PLoS ONE, 2017, v. 12, n. 8, p. 1, doi. 10.1371/journal.pone.0182382

By:

Kwon, Eunju;
Pathak, Deepak;
Chang, Hyeun Wook;
Kim, Dong Young

Publication type:

Article

Improved cytotoxic effects of S almonella-producing cytosine deaminase in tumour cells.

Published in:

Microbial Biotechnology, 2015, v. 8, n. 1, p. 169, doi. 10.1111/1751-7915.12153

By:

Mesa-Pereira, Beatriz;
Medina, Carlos;
Camacho, Eva María;
Flores, Amando;
Santero, Eduardo

Publication type:

Article

Effects of Genetically Engineered Stem Cells Expressing Cytosine Deaminase and Interferon-Beta or Carboxyl Esterase on the Growth of LNCaP Prostate Cancer Cells.

Published in:

International Journal of Molecular Sciences, 2012, v. 13, n. 10, p. 12519, doi. 10.3390/ijms131012519

By:

Bo-Rim Yi;
Kyung-A. Hwang;
Yun-Bae Kim;
Seung U. Kim;
Kyung-Chul Choi

Publication type:

Article

Inhibition of Tumor Growth by Polyarginine-Fused Mutant Cytosine Deaminase.

Published in:

Applied Biochemistry & Biotechnology, 2015, v. 175, n. 3, p. 1633, doi. 10.1007/s12010-014-1389-x

By:

Wang, Wenfei;
Zhang, Nan;
Zhao, Tingting;
Liu, Mingyao;
Zhang, Tong;
Li, Deshan

Publication type:

Article

Genomic instability: DNA transitions.

Published in:

Nature Reviews Cancer, 2013, v. 13, n. 4, p. 220, doi. 10.1038/nrc3490

By:

Alderton, Gemma K.

Publication type:

Article

Characterization and Cytotoxic Activity of Cytosine Deaminase Enzyme Purified from Locally Isolated Escherichia coli.

Published in:

Baghdad Science Journal, 2018, v. 15, n. 3, p. 262, doi. 10.21123/bsj.2018.15.3.0262

By:

Hussein, Asmaa A.;
Al-Baer, Ali Saadi

Publication type:

Article

AID/APOBEC cytosine deaminase induces genome-wide kataegis.

Published in:

Biology Direct, 2012, v. 7, n. 1, p. 47, doi. 10.1186/1745-6150-7-47

By:

Lada, Artem G.;
Dhar, Alok;
Boissy, Robert J.;
Hirano, Masayuki;
Rubel, Aleksandr A.;
Rogozin, Igor B.;
Pavlov, Youri I.

Publication type:

Article

Natural APOBEC3C variants can elicit differential HIV-1 restriction activity.

Published in:

Retrovirology, 2018, v. 15, n. 1, p. N.PAG, doi. 10.1186/s12977-018-0459-5

By:

Anderson, Brett D.;
Ikeda, Terumasa;
Moghadasi, Seyed Arad;
Martin, Amber St.;
Brown, William L.;
Harris, Reuben S.

Publication type:

Article

Baculoviral vector loaded mesenchymal stem cells as efficient gene therapy tools for cancer treatment.

Published in:

Turkish Journal of Biology, 2016, v. 40, n. 5, p. 1121, doi. 10.3906/biy-1601-76

By:

AKTAŞ, Sedef Hande;
AKBULUT, Hakan;
ELÇİN, Ayşe Eser;
PARMAKSIZ, Mahmut;
KESKİN, Arzu Aktan;
ÇÖLERİ CİHAN, Arzu;
ELÇİN, Yaşar Murat;
İÇLİ, Fikri

Publication type:

Article

New look at the role of progerin in skin aging.

Published in:

Menopausal Review / Przegląd Menopauzalny, 2015, v. 14, n. 1, p. 53, doi. 10.5114/pm.2015.49532

By:

Skoczyńska, Anna;
Budzisz, Elżbieta;
Dana, Agnieszka;
Rotsztejn, Helena

Publication type:

Article

Chemovirotherapy of Malignant Melanoma with a Targeted and Armed Oncolytic Measles Virus.

Published in:

Journal of Investigative Dermatology, 2013, v. 133, n. 4, p. 1034, doi. 10.1038/jid.2012.459

By:

Kaufmann, Johanna K;
Bossow, Sascha;
Grossardt, Christian;
Sawall, Stefanie;
Kupsch, Jörg;
Erbs, Philippe;
Hassel, Jessica C;
von Kalle, Christof;
Enk, Alexander H;
Nettelbeck, Dirk M;
Ungerechts, Guy

Publication type:

Article

Radiosensitization of gliomas by intracellular generation of 5-fluorouracil potentiates prodrug activator gene therapy with a retroviral replicating vector.

Published in:

Cancer Gene Therapy, 2014, v. 21, n. 10, p. 405, doi. 10.1038/cgt.2014.38

By:

Takahashi, M.;
Valdes, G.;
Hiraoka, K.;
Inagaki, A.;
Kamijima, S.;
Micewicz, E.;
Gruber, H. E.;
Robbins, J. M.;
Jolly, D. J.;
McBride, W. H.;
Iwamoto, K. S.;
Kasahara, N.

Publication type:

Article

Toca 511 gene transfer and 5-fluorocytosine in combination with temozolomide demonstrates synergistic therapeutic efficacy in a temozolomide-sensitive glioblastoma model.

Published in:

Cancer Gene Therapy, 2013, v. 20, n. 10, p. 544, doi. 10.1038/cgt.2013.51

By:

Huang, T T;
Hlavaty, J;
Ostertag, D;
Espinoza, F L;
Martin, B;
Petznek, H;
Rodriguez-Aguirre, M;
Ibañez, C E;
Kasahara, N;
Gunzburg, W;
Gruber, H E;
Pertschuk, D;
Jolly, D J;
Robbins, J M

Publication type:

Article

Convection-enhanced delivery improves distribution and efficacy of tumor-selective retroviral replicating vectors in a rodent brain tumor model.

Published in:

Cancer Gene Therapy, 2013, v. 20, n. 6, p. 336, doi. 10.1038/cgt.2013.25

By:

Yin, D.;
Zhai, Y.;
Gruber, H. E.;
Ibanez, C. E.;
Robbins, J. M.;
Kells, A. P.;
Kasahara, N.;
Forsayeth, J.;
Jolly, D. J.;
Bankiewicz, K. S.

Publication type:

Article

Neural stem cell-based dual suicide gene delivery for metastatic brain tumors.

Published in:

Cancer Gene Therapy, 2012, v. 19, n. 11, p. 796, doi. 10.1038/cgt.2012.63

By:

Wang, C;
Natsume, A;
Lee, H J;
Motomura, K;
Nishimira, Y;
Ohno, M;
Ito, M;
Kinjo, S;
Momota, H;
Iwami, K;
Ohka, F;
Wakabayashi, T;
Kim, S U

Publication type:

Article

Management of malignant pleural effusion by suicide gene therapy in advanced stage lung cancer: a case series and literature review.

Published in:

Cancer Gene Therapy, 2012, v. 19, n. 9, p. 593, doi. 10.1038/cgt.2012.36

By:

Zarogoulidis, P;
Chatzaki, E;
Hohenforst-Schmidt, W;
Goldberg, E P;
Galaktidou, G;
Kontakiotis, T;
Karamanos, N;
Zarogoulidis, K

Publication type:

Article

Synergistic effects of genetically engineered stem cells expressing cytosine deaminase and interferon-β via their tumor tropism to selectively target human hepatocarcinoma cells.

Published in:

Cancer Gene Therapy, 2012, v. 19, n. 9, p. 644, doi. 10.1038/cgt.2012.45

By:

Yi, B-R;
Hwang, K-A;
Kang, N-H;
Kim, S U;
Jeung, E-B;
Kim, H-C;
Choi, K-C

Publication type:

Article

Therapeutic effect of suicide gene-transferred mesenchymal stem cells in a rat model of glioma.

Published in:

Cancer Gene Therapy, 2012, v. 19, n. 8, p. 572, doi. 10.1038/cgt.2012.35

By:

Kosaka, H;
Ichikawa, T;
Kurozumi, K;
Kambara, H;
Inoue, S;
Maruo, T;
Nakamura, K;
Hamada, H;
Date, I

Publication type:

Article

Human amniotic fluid-derived stem cells expressing cytosine deaminase and thymidine kinase inhibits the growth of breast cancer cells in cellular and xenograft mouse models.

Published in:

Cancer Gene Therapy, 2012, v. 19, n. 6, p. 412, doi. 10.1038/cgt.2012.15

By:

Kang, N-H;
Hwang, K-A;
Yi, B-R;
Lee, H J;
Jeung, E-B;
Kim, S U;
Choi, K-C

Publication type:

Article

Hypoxia imaging predicts success of hypoxia-induced cytosine deaminase/5-fluorocytosine gene therapy in a murine lung tumor model.

Published in:

Cancer Gene Therapy, 2012, v. 19, n. 4, p. 255, doi. 10.1038/cgt.2011.87

By:

Lee, B-F;
Lee, C-H;
Chiu, N-T;
Hsia, C-C;
Shen, L-H;
Shiau, A-L

Publication type:

Article

Oncolytic Herpes simplex virus expressing yeast cytosine deaminase: relationship between viral replication, transgene expression, prodrug bioactivation.

Published in:

Cancer Gene Therapy, 2012, v. 19, n. 3, p. 160, doi. 10.1038/cgt.2011.70

By:

Yamada, S;
Kuroda, T;
Fuchs, B C;
He, X;
Supko, J G;
Schmitt, A;
McGinn, C M;
Lanuti, M;
Tanabe, K K

Publication type:

Article

VP22 and cytosine deaminase fusion gene modified tissue-engineered neural stem cells for glioma therapy.

Published in:

Journal of Cancer Research & Clinical Oncology, 2013, v. 139, n. 3, p. 475, doi. 10.1007/s00432-012-1347-3

By:

Jin, Guishan;
Zhou, Yiqiang;
Chai, Qi;
Zhu, Guidong;
Xu, Fujian;
Liu, Fusheng

Publication type:

Article