Works matching DE "CYTOCHROME P-450 CYP3A"
Results: 669
A Drug–Drug Interaction Study of Mobocertinib and Midazolam, a Cytochrome P450 3A Substrate, in Patients With Advanced Non–Small Cell Lung Cancer.
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- Clinical Pharmacology in Drug Development, 2025, v. 14, n. 3, p. 252, doi. 10.1002/cpdd.1500
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- Article
Discovery of a Novel Multitarget Analgesic Through an In Vivo-Guided Approach.
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- Pharmaceuticals (14248247), 2025, v. 18, n. 2, p. 205, doi. 10.3390/ph18020205
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- Article
CYP3A Mediates an Unusual C(sp<sup>2</sup>)−C(sp<sup>3</sup>) Bond Cleavage via Ipso‐Addition of Oxygen in Drug Metabolism.
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- Angewandte Chemie, 2024, v. 136, n. 23, p. 1, doi. 10.1002/ange.202405197
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- Article
Rational Design of a Two‐Photon Fluorescent Probe for Human Cytochrome P450 3A and the Visualization of Mechanism‐Based Inactivation.
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- Angewandte Chemie, 2022, v. 134, n. 5, p. 1, doi. 10.1002/ange.202113191
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- Article
Does One Size Fits All?
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- Cardiovascular Drugs & Therapy, 2024, v. 38, n. 6, p. 1099, doi. 10.1007/s10557-024-07625-6
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- Article
Mutant CYP3A4/5 Correlated with Clinical Outcomes by Affecting Rivaroxaban Pharmacokinetics and Pharmacodynamics in Patients with Atrial Fibrillation.
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- Cardiovascular Drugs & Therapy, 2024, v. 38, n. 6, p. 1315, doi. 10.1007/s10557-023-07495-4
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- Article
Effect of Clarithromycin, a Strong CYP3A and P-glycoprotein Inhibitor, on the Pharmacokinetics of Edoxaban in Healthy Volunteers and the Evaluation of the Drug Interaction with Other Oral Factor Xa Inhibitors by a Microdose Cocktail Approach.
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- Cardiovascular Drugs & Therapy, 2024, v. 38, n. 4, p. 747, doi. 10.1007/s10557-023-07443-2
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- Article
Comparative Muscle Tolerability of Different Types and Intensities of Statins: A Network Meta-Analysis of Double-Blind Randomized Controlled Trials.
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- Cardiovascular Drugs & Therapy, 2024, v. 38, n. 3, p. 459, doi. 10.1007/s10557-022-07405-0
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- Article
Quantitative analysis of the impact of membrane permeability on intestinal first‐pass metabolism of CYP3A substrates.
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- Biopharmaceutics & Drug Disposition, 2024, v. 45, n. 1, p. 3, doi. 10.1002/bdd.2379
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- Article
Evaluation of bleeding and anticoagulation markers by edoxaban and low‐dose cyclosporine: A case series study.
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- Biopharmaceutics & Drug Disposition, 2022, v. 43, n. 5, p. 192, doi. 10.1002/bdd.2332
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- Article
Effects of osthol on activity, mRNA and protein expression of Cyp3a in rats in vivo.
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- Biopharmaceutics & Drug Disposition, 2020, v. 41, n. 1/2, p. 64, doi. 10.1002/bdd.2214
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- Article
Effects of Aspirin on the Bioavailability and Pharmacokinetics of Repaglinide: Possible Role of Cytochrome P450 3A Isoforms Inhibition by Aspirin.
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- Pharmaceutical Chemistry Journal, 2022, v. 55, n. 11, p. 1151, doi. 10.1007/s11094-022-02551-z
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- Article
Insights into oral bioavailability enhancement of therapeutic herbal constituents by cytochrome P450 3A inhibition.
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- Drug Metabolism Reviews, 2021, v. 53, n. 4, p. 491, doi. 10.1080/03602532.2021.1917598
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- Article
Effect of donor GSTM3 rs7483 genetic variant on tacrolimus elimination in the early period after liver transplantation.
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- PeerJ, 2024, p. 1, doi. 10.7717/peerj.18360
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- Article
The effect of gene polymorphism on ticagrelor metabolism: an in vitro study of 22 CYP3A4 variants in Chinese Han population.
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- PeerJ, 2024, p. 1, doi. 10.7717/peerj.18109
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- Article
Effects of the CYP3A inhibitors, voriconazole, itraconazole, and fluconazole on the pharmacokinetics of osimertinib in rats.
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- PeerJ, 2023, p. 1, doi. 10.7717/peerj.15844
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- Article
TNP and its analogs: Modulation of IP6K and CYP3A4 inhibition.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2022, v. 37, n. 1, p. 269, doi. 10.1080/14756366.2021.2000404
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- Article
Evaluation of weight loss supplements toxicity in rifampicin pretreated HepG2 cells.
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- Macedonian Pharmaceutical Bulletin / Makedonsko Farmacevtski Bilten, 2023, v. 69, p. 257, doi. 10.33320/maced.pharm.bull.2023.69.03.126
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- Article
In silico prediction of physicochemical, pharmacokinetic and toxicological properties of sulforaphane.
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- Macedonian Pharmaceutical Bulletin / Makedonsko Farmacevtski Bilten, 2022, v. 68, p. 331, doi. 10.33320/maced.pharm.bull.2022.68.03.159
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- Article
Toxicity assessment of weight loss supplements and possible interaction risk with lipid-lowering and antihypertensive drugs in HepG2 cell line.
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- Macedonian Pharmaceutical Bulletin / Makedonsko Farmacevtski Bilten, 2022, v. 68, p. 321, doi. 10.33320/maced.pharm.bull.2022.68.03.154
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- Article
Tacrolimus Concentration Is Effectively Predicted Using Combined Clinical and Genetic Factors in the Perioperative Period of Kidney Transplantation and Associated with Acute Rejection.
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- 2022
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- journal article
The effects of vitamins C and E on the redox parameters of cytochrome P450 3A4.
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- Zeitschrift für Physikalische Chemie, 2023, v. 237, n. 12, p. 1925, doi. 10.1515/zpch-2023-0303
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- Article
Tolterodine is a novel candidate for assessing CYP3A4 activity through metabolic volatiles to predict drug responses.
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- Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-86450-9
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- Article
Author Correction: Responses in organs, sperm, steroid hormones and CYP450 enzyme in male mice treated by quinestrol only or in conjunction with clarithromycin.
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- 2024
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- Correction Notice
OCT1 (SLC22A1) transporter kinetics and regulation in primary human hepatocyte 3D spheroids.
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- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-67192-6
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- Article
Efficient hepatocyte differentiation of primary human hepatocyte-derived organoids using three dimensional nanofibers (HYDROX) and their possible application in hepatotoxicity research.
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- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-61544-y
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- Article
CYP2C8 rs11572080 and CYP3A4 rs2740574 risk genotypes in paclitaxel-treated premenopausal breast cancer patients.
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- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-58104-9
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- Article
CYP3A-Mediated Carbon–Carbon Bond Cleavages in Drug Metabolism.
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- Biomolecules (2218-273X), 2024, v. 14, n. 9, p. 1125, doi. 10.3390/biom14091125
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- Article
The Role of Intestinal Cytochrome P450s in Vitamin D Metabolism.
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- Biomolecules (2218-273X), 2024, v. 14, n. 6, p. 717, doi. 10.3390/biom14060717
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- Article
Exploring the Potential of Sulfur Moieties in Compounds Inhibiting Steroidogenesis.
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- Biomolecules (2218-273X), 2023, v. 13, n. 9, p. 1349, doi. 10.3390/biom13091349
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- Article
Differential Metabolic Stability of 4α,25- and 4β,25-Dihydroxyvitamin D 3 and Identification of Their Metabolites.
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- Biomolecules (2218-273X), 2023, v. 13, n. 7, p. 1036, doi. 10.3390/biom13071036
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- Article
Functional and Structural Impact of Deleterious Missense Single Nucleotide Polymorphisms in the NR3C1, CYP3A5, and TNF-α Genes: An In Silico Analysis.
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- Biomolecules (2218-273X), 2022, v. 12, n. 9, p. 1307, doi. 10.3390/biom12091307
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- Article
Midazolam as a Probe for Heterotropic Drug-Drug Interactions Mediated by CYP3A4.
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- Biomolecules (2218-273X), 2022, v. 12, n. 6, p. 853, doi. 10.3390/biom12060853
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- Article
Synthesis and Structure–Activity Relationships of Novel Non-Steroidal CYP17A1 Inhibitors as Potential Prostate Cancer Agents.
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- Biomolecules (2218-273X), 2022, v. 12, n. 2, p. 165, doi. 10.3390/biom12020165
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- Article
Preparative Production of Functionalized (N - and O -Heterocyclic) Polycyclic Aromatic Hydrocarbons by Human Cytochrome P450 3A4 in a Bioreactor.
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- Biomolecules (2218-273X), 2022, v. 12, n. 2, p. 153, doi. 10.3390/biom12020153
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- Article
Improving the Efficiency of Electrocatalysis of Cytochrome P450 3A4 by Modifying the Electrode with Membrane Protein Streptolysin O for Studying the Metabolic Transformations of Drugs.
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- Biosensors (2079-6374), 2023, v. 13, n. 4, p. 457, doi. 10.3390/bios13040457
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- Article
Cocaine regulates antiretroviral therapy CNS access through pregnane-x receptor-mediated drug transporter and metabolizing enzyme modulation at the blood brain barrier.
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- Fluids & Barriers of the CNS, 2024, v. 21, n. 1, p. 1, doi. 10.1186/s12987-023-00507-3
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- Article
Changes in CYP3A4 Enzyme Expression and Biochemical Markers Under Acute Hypoxia Affect the Pharmacokinetics of Sildenafil.
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- Frontiers in Physiology, 2022, v. 12, p. 1, doi. 10.3389/fphys.2022.755769
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- Article
Rhabdomyolysis Risk: The Dangers of Tribulus terrestris, an Over-the-Counter Supplement.
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- 2024
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- Case Study
Puromycin-based purification of cells with high expression of the cytochrome P450 CYP3A4 gene from a patient with drug-induced liver injury (DILI).
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- Stem Cell Research & Therapy, 2022, v. 13, n. 1, p. 1, doi. 10.1186/s13287-021-02680-4
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- Article
Examining the Characteristics of Colchicine-Induced Myelosuppression in Clinical Cases: A Systematic Review.
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- Journal of Rheumatology, 2023, v. 50, n. 3, p. 400, doi. 10.3899/jrheum.220524
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- Article
Lumateperone for major depressive episodes in bipolar I or bipolar II disorder.
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- Current Psychiatry, 2022, v. 21, n. 3, p. 44, doi. 10.12788/cp.0227
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- Article
Increasing the Efficiency of Cytochrome P450 3A4 Electrocatalysis Using Electrode Modification with Spatially Ordered Anodic Aluminum Oxide-Based Nanostructures for Investigation of Metabolic Transformations of Drugs.
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- Doklady Biochemistry & Biophysics, 2022, v. 506, n. 1, p. 215, doi. 10.1134/S1607672922050131
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- Article
Correlated downregulation of VDR and CYP3A4 in colorectal cancer.
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- Molecular Biology Reports, 2023, v. 50, n. 2, p. 1385, doi. 10.1007/s11033-022-08141-2
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- Article
Mixology: seeking the right prescription for atrial fibrillation.
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- Journal of Interventional Cardiac Electrophysiology, 2023, v. 66, n. 6, p. 1303, doi. 10.1007/s10840-022-01415-6
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- Article
CYP3A Polymorphism and Chronic Mercury Intoxication.
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- Bulletin of Experimental Biology & Medicine, 2020, v. 168, n. 4, p. 492, doi. 10.1007/s10517-020-04738-4
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- Article
Evaluation of machine learning models for cytochrome P450 3A4, 2D6, and 2C9 inhibition.
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- Journal of Applied Toxicology, 2024, v. 44, n. 7, p. 1050, doi. 10.1002/jat.4601
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- Article
Physiologically based pharmacokinetic modeling for confirming the role of CYP3A1/2 and P‐glycoprotein in detoxification mechanism between glycyrrhizic acid and aconitine in rats.
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- Journal of Applied Toxicology, 2024, v. 44, n. 7, p. 978, doi. 10.1002/jat.4595
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- Article
Nitrophenols disrupt the expression and activity of biotransformation enzymes (CYP3A and COMT) in chicken ovarian follicles in vivo and in vitro.
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- Journal of Applied Toxicology, 2024, v. 44, n. 5, p. 756, doi. 10.1002/jat.4573
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- Article
Boscalid shows increased thyroxin‐glucuronidation in rat but not in human hepatocytes in vitro.
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- Journal of Applied Toxicology, 2023, v. 43, n. 6, p. 828, doi. 10.1002/jat.4427
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- Article