Works matching DE "CYTOCHROME P-450 CYP2D6"

Results: 481

Physiologically Based Pharmacokinetic Model of CYP2D6 Associated Interaction Between Venlafaxine and Strong Inhibitor Bupropion—The Influence of Age-Relevant Changes and Inhibitory Dose to Classify Therapeutical Success and Harm.
Published in:
Pharmaceutics, 2025, v. 17, n. 2, p. 179, doi. 10.3390/pharmaceutics17020179
By:
- Luecht, Ulrich Ruben;
- Scholz, Wolfgang;
- Geiben, Ann-Kathrin;
- Haen, Ekkehard;
- Hempel, Georg
Publication type:
Article
Nanopore sequencing-based genotyping suggested an association between CYP2D6 function and susceptibility to anxiety and depression.
Published in:
BMC Research Notes, 2025, v. 18, n. 1, p. 1, doi. 10.1186/s13104-025-07156-9
By:
- Chua, Eng Wee;
- Karunanathie, Harsheni;
- Yanasegaran, Kevina;
- Maggo, Simran;
- Kee, Ping Siu;
- Kennedy, Martin;
- Abdul Manaf, Mohd Rizal;
- Ng, Pei Yuen
Publication type:
Article
The analysis of methylxanthine fractions obtained from Camellia sinensis cultivated in Turkey and effects on the in vitro inhibition of CYP2D6 enzyme.
Published in:
Biotechnology & Applied Biochemistry, 2023, v. 70, n. 1, p. 22, doi. 10.1002/bab.2325
By:
- Attar, Azade;
- Altikatoglu Yapaoz, Melda
Publication type:
Article
Drug metabolizing enzymes-associated chemo resistance and strategies to overcome it.
Published in:
Drug Metabolism Reviews, 2019, v. 51, n. 2, p. 196, doi. 10.1080/03602532.2019.1632886
By:
- Verma, Himanshu;
- Singh Bahia, Malkeet;
- Choudhary, Shalki;
- Kumar Singh, Pankaj;
- Silakari, Om
Publication type:
Article
Loss of Heterozygosity at the CYP2D6 Locus in Breast Cancer: Implications for Tamoxifen Pharmacogenetic Studies.
Published in:
2015
By:
- Johnson, Julie A.;
- Hamadeh, Issam S.;
- Langaee, Taimour Y.
Publication type:
Editorial
Re: Concordance Between CYP2D6 Genotypes Obtained From Tumor-Derived and Germline DNA.
Published in:
2014
By:
- BERRY, DONALD A.
Publication type:
Letter to the Editor
Re: Concordance Between CYP2D6 Genotypes Obtained From Tumor-Derived and Germline DNA.
Published in:
2014
By:
- RAE, JAMES M.;
- LEYLAND-JONES, BRIAN;
- REGAN, MEREDITH
Publication type:
Letter to the Editor
Re: Concordance Between CYP2D6 Genotypes Obtained From Tumor-Derived and Germline DNA.
Published in:
2014
By:
- GOETZ, MATTHEW P.;
- BRAUCH, HILTRUD;
- RATAIN, MARK J.;
- COX, NANCY J.;
- NAKAMURA, YUSUKE;
- WEINSHILBOUM, RICHARD;
- INGLE, JAMES N.
Publication type:
Letter to the Editor
Concordance Between CYP2D6 Genotypes Obtained From Tumor-Derived and Germline DNA.
Published in:
JNCI: Journal of the National Cancer Institute, 2013, v. 105, n. 17, p. 1332, doi. 10.1093/jnci/djt204
By:
- Rae, James M.;
- Regan, Meredith M.;
- Thibert, Jacklyn N.;
- Gersch, Christina;
- Thomas, Dafydd;
- Leyland-Jones, Brian;
- Viale, Giuseppe;
- Pusztai, Lajos;
- Hayes, Daniel E.;
- Skaar, Todd;
- Van Poznak, Catherine
Publication type:
Article
Re: CYP2D6 Genotype and Tamoxifen Response in Postmenopausal Women With Endocrine-Responsive Breast Cancer: The Breast International Group 1-98 Trial.
Published in:
2012
By:
- Nakamura, Yusuke;
- Ratain, Mark J.;
- Cox, Nancy J.;
- Mcleod, Howard L.;
- Kroetz, Deanna L.;
- Flockhart, David A.
Publication type:
Letter
Re: CYP2D6 Genotype and Tamoxifen Response in Postmenopausal Women With Endocrine-Responsive Breast Cancer: The Breast International Group 1-98 Trial and Re: CYP2D6 and UGT2B7 Genotype and Risk of Recurrence in Tamoxifen-Treated Breast Cancer Patients.
Published in:
2012
By:
- Pharoah, Paul D. P.;
- Abraham, Jean;
- Caldas, Carlos
Publication type:
Letter
Re: CYP2D6 Genotype and Tamoxifen Response in Postmenopausal Women With Endocrine-Responsive Breast Cancer: The Breast International Group 1–98 Trial.
Published in:
JNCI: Journal of the National Cancer Institute, 2012, v. 104, n. 16, p. 1265, doi. 10.1093/jnci/djs305
By:
- Stanton, Vincent
Publication type:
Article
Response.
Published in:
2012
By:
- Rae, James M.;
- Hayes, Daniel F.;
- Cuzick, Jack;
- Sestak, Ivana;
- Dowsett, Mitch
Publication type:
Letter
Response.
Published in:
2012
By:
- Regan, Meredith M.;
- Bouzyk, Mark;
- Rae, James M.;
- Viale, Giuseppe;
- Leyland-Jones, Brian
Publication type:
Letter
CYP2D6 Genotype and Tamoxifen Response in Postmenopausal Women with Endocrine-Responsive Breast Cancer: The Breast International Group 1-98 Trial.
Published in:
JNCI: Journal of the National Cancer Institute, 2012, v. 104, n. 6, p. 441, doi. 10.1093/jnci/djs125
By:
- Regan, Meredith M.;
- Leyland-Jones, Brian;
- Bouzyk, Mark;
- Pagani, Olivia;
- Tang, Weining;
- Kammler, Roswitha;
- Dell’Orto, Patrizia;
- Biasi, Maria Olivia;
- Thürlimann, Beat;
- Lyng, Maria B.;
- Ditzel, Henrik J.;
- Neven, Patrick;
- Debled, Marc;
- Maibach, Rudolf;
- Price, Karen N.;
- Gelber, Richard D.;
- Coates, Alan S.;
- Goldhirsch, Aron;
- Rae, James M.;
- Viale, Giuseppe
Publication type:
Article
CYP2D6 and UGT2B7 Genotype and Risk of Recurrence in Tamoxifen-Treated Breast Cancer Patients.
Published in:
JNCI: Journal of the National Cancer Institute, 2012, v. 104, n. 6, p. 452, doi. 10.1093/jnci/djs126
By:
- Rae, James M.;
- Drury, Suzy;
- Hayes, Daniel F.;
- Stearns, Vered;
- Thibert, Jacklyn N.;
- Haynes, Ben P.;
- Salter, Janine;
- Sestak, Ivana;
- Cuzick, Jack;
- Dowsett, Mitch
Publication type:
Article
In This Issue.
Published in:
JNCI: Journal of the National Cancer Institute, 2012, v. 104, n. 6, p. 425, doi. 10.1093/jnci/djs171
Publication type:
Article
CYP2D6 Genotype as a Marker for Benefit of Adjuvant Tamoxifen in Postmenopausal Women: Lessons Learned.
Published in:
JNCI: Journal of the National Cancer Institute, 2012, v. 104, n. 6, p. 427, doi. 10.1093/jnci/djs139
By:
- Kelly, Catherine M.;
- Pritchard, Kathleen I.
Publication type:
Article
Concomitant influence of CYP2D6 phenotype and ABCB1 overall haplotype/genotype on pharmacokinetics of risperidone and 9-hydroxyrisperidone in healthy volunteers.
Published in:
Macedonian Pharmaceutical Bulletin / Makedonsko Farmacevtski Bilten, 2022, v. 68, p. 393, doi. 10.33320/maced.pharm.bull.2022.68.03.189
By:
- Dimkovski, Aleksandar;
- Mihajloska, Evgenija;
- Jakovski, Krume;
- Sterjev, Zoran;
- Matevska Geskovska, Nadica;
- Naumovska, Zorica;
- Kapedanovska Nestorovska, Aleksandra;
- Suturkova, Ljubica;
- Dimovski, Aleksandar
Publication type:
Article
Determining The Enhancing Effects Of PCR Additives On Long- Range PCR.
Published in:
2022
By:
- Karunanathie, Harsheni;
- Eng Wee Chua
Publication type:
Abstract
Influence of ABCB1 polymorphisms on aripiprazole and dehydroaripiprazole plasma concentrations.
Published in:
Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-024-84192-8
By:
- Toja-Camba, Francisco José;
- Vidal-Millares, María;
- Durán-Maseda, María José;
- Hermelo-Vidal, Gonzalo;
- Carracedo, Ángel;
- Maroñas, Olalla;
- Ramudo-Cela, Luis;
- Zarra-Ferro, Irene;
- Fernández-Ferreiro, Anxo;
- Mondelo-García, Cristina
Publication type:
Article
The variation landscape of CYP2D6 in a multi-ethnic Asian population.
Published in:
Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-67691-6
By:
- Maulana, Yusuf;
- Toro Jimenez, Rodrigo;
- Twesigomwe, David;
- Sani, Levana;
- Irwanto, Astrid;
- Bertin, Nicolas;
- Gonzalez-Porta, Mar
Publication type:
Article
PK/PD investigation of antiviral host matriptase/TMPRSS2 inhibitors in cell models.
Published in:
Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-67633-2
By:
- Gamba, Dávid;
- van Eijk, Nicholas;
- Lányi, Katalin;
- Monostory, Katalin;
- Steinmetzer, Torsten;
- Marosi, András;
- Rácz, Anita;
- Bajusz, Dávid;
- Kruhl, Diana;
- Böttcher-Friebertshäuser, Eva;
- Pászti-Gere, Erzsébet
Publication type:
Article
Cytochrome P450-2D6*4 polymorphism seminal relationship in infertile men.
Published in:
Andrologia, 2015, v. 47, n. 5, p. 525, doi. 10.1111/and.12298
By:
- Zalata, A.;
- El‐Samanoudy, A. Z.;
- Osman, G.;
- Elhanbly, S.;
- Nada, H. A.;
- Mostafa, T.
Publication type:
Article
Phenoconversion of CYP2D6 by inhibitors modifies aripiprazole exposure.
Published in:
European Archives of Psychiatry & Clinical Neuroscience, 2020, v. 270, n. 1, p. 71, doi. 10.1007/s00406-018-0975-2
By:
- Kiss, Ádám;
- Menus, Ádám;
- Tóth, Katalin;
- Déri, Máté;
- Sirok, Dávid;
- Gabri, Evelyn;
- Belic, Ales;
- Csukly, Gábor;
- Bitter, István;
- Monostory, Katalin
Publication type:
Article
Low-Dose Tramadol-Induced Seizure: A Case Report.
Published in:
Journal of Pharmacology & Pharmacotherapeutics, 2022, v. 13, n. 2, p. 203, doi. 10.1177/0976500X221107494
By:
- Dasgupta, Himadri Sekhar;
- Sahoo, Debashis Priyadarshan;
- Barman, Bhupen;
- Brahma, Dhriti
Publication type:
Article
The Utility of CYP2D6 and CYP2C19 Variants to Guide Pharmacological Treatment in Complex Unipolar Major Depression: A Pilot Longitudinal Study.
Published in:
Psychiatric Quarterly, 2023, v. 94, n. 3, p. 435, doi. 10.1007/s11126-023-10044-9
By:
- Ramaraj, Reshma;
- Al-Mahayri, Zeina N.;
- Saleous, Reema;
- Abdel Aziz, Karim;
- Al-Mugaddam, Fadwa;
- Al-Sabousi, Mouza;
- Alhassani, Aysha;
- Ahbabi, Noura Ali Al;
- Stip, Emmanuel;
- Patrinos, George P.;
- Ali, Bassam R.;
- Arnone, Danilo
Publication type:
Article
Assessing Clinical Utility of Pharmacogenetic Testing in the Military Health System.
Published in:
Military Medicine, 2024, v. 189, n. 1/2, p. e198, doi. 10.1093/milmed/usad254
By:
- Hellwig, Lydia D;
- Turner, Clesson;
- Olsen, Cara;
- Libbus, Joya;
- Markos, Bethelhem;
- Koehlmoos, Tracey;
- Haigney, Mark;
- De Castro, Mauricio;
- Saunders, David
Publication type:
Article
Prescription Patterns and Relationship to Pharmacogenomics Testing in the Military Health System.
Published in:
2022
By:
- Selig, Daniel J;
- Livezey, Jeffrey R;
- Chin, Geoffrey C;
- DeLuca, Jesse P;
- II, Walter O Guillory;
- Kress, Adrian T;
- Oliver, Thomas O;
- Por, Elaine D;
- Guillory Ii, Walter O
Publication type:
journal article
Unidentified CYP2D6 genotype does not affect pharmacological treatment for patients with first episode psychosis.
Published in:
Journal of Psychopharmacology, 2024, v. 38, n. 12, p. 1111, doi. 10.1177/02698811241279022
By:
- De Brabander, Emma Y;
- van Amelsvoort, Thérèse;
- van Westrhenen, Roos
Publication type:
Article
Clinical effects of CYP2D6 phenoconversion in patients with psychosis.
Published in:
Journal of Psychopharmacology, 2024, v. 38, n. 12, p. 1095, doi. 10.1177/02698811241278844
By:
- De Brabander, Emma Y;
- Breddels, Esmee;
- van Amelsvoort, Therese;
- van Westrhenen, Roos
Publication type:
Article
Long-read sequencing of CYP2D6 may improve psychotropic prescribing and treatment outcomes: A systematic review and meta-analysis.
Published in:
Journal of Psychopharmacology, 2024, v. 38, n. 9, p. 771, doi. 10.1177/02698811241268899
By:
- Kaptsis, Dean;
- Lewis, Martin;
- Sorich, Michael;
- Battersby, Malcolm
Publication type:
Article
The pharmacokinetics and pharmacodynamics of ibogaine in opioid use disorder patients.
Published in:
Journal of Psychopharmacology, 2024, v. 38, n. 5, p. 481, doi. 10.1177/02698811241237873
By:
- Knuijver, Thomas;
- ter Heine, Rob;
- Schellekens, Arnt F. A.;
- Heydari, Paniz;
- Lucas, Luc;
- Westra, Sjoerd;
- Belgers, Maarten;
- van Oosteren, Toon;
- Verkes, Robbert Jan;
- Kramers, Cornelis
Publication type:
Article
Proportion of Antipsychotics with CYP2D6 Pharmacogenetic (PGx) Associations Prescribed in an Early Intervention in Psychosis (EIP) Cohort: A Cross-Sectional Study.
Published in:
Journal of Psychopharmacology, 2024, v. 38, n. 4, p. 382, doi. 10.1177/02698811241238283
By:
- Jameson, Adam;
- Faisal, Muhammad;
- Fylan, Beth;
- Bristow, Greg C;
- Sohal, Jaspreet;
- Dalton, Caroline;
- Sagoo, Gurdeep S;
- Cardno, Alastair G;
- McLean, Samantha L
Publication type:
Article
Associations of antidepressants and antipsychotics with lipid parameters: Do CYP2C19 / CYP2D6 genes play a role? A UK population-based study.
Published in:
Journal of Psychopharmacology, 2023, v. 37, n. 4, p. 396, doi. 10.1177/02698811231152748
By:
- Richards-Belle, Alvin;
- Austin-Zimmerman, Isabelle;
- Wang, Baihan;
- Zartaloudi, Eirini;
- Cotic, Marius;
- Gracie, Caitlin;
- Saadullah Khani, Noushin;
- Wannasuphoprasit, Yanisa;
- Wronska, Marta;
- Dawda, Yogita;
- Osborn, David PJ;
- Bramon, Elvira
Publication type:
Article
Prediction of MDMA response in healthy humans: a pooled analysis of placebo-controlled studies.
Published in:
2021
By:
- Studerus, Erich;
- Vizeli, Patrick;
- Harder, Samuel;
- Ley, Laura;
- Liechti, Matthias E
Publication type:
journal article
Association of tardive dyskinesia with variation in CYP2D6: Is there a role for active metabolites?
Published in:
2014
By:
- Koola, Maju M;
- Tsapakis, Evangelia M;
- Wright, Padraig;
- Smith, Shubulade;
- Kerwin (RIP), Robert W;
- Nugent, Katie L;
- Aitchison, Katherine J
Publication type:
journal article
Case report: recurrence of Plasmodium vivax malaria due to defective cytochrome P450 2D6 function in Pos Lenjang, Pahang, Malaysia.
Published in:
Transactions of the Royal Society of Tropical Medicine & Hygiene, 2020, v. 114, n. 9, p. 700, doi. 10.1093/trstmh/traa042
By:
- Salleh, Noor Hafizan Mat;
- Rahman, Mohd Faizal Abdul;
- Samsusah, Samsiah;
- Silva, Jeremy Ryan De;
- Ng, David Chun-Ern;
- Ghozali, Azilawati Hanim;
- Tan, Jia Hui;
- Lai, Meng Yee;
- Amir, Amirah;
- Liew, Jonathan Wee Kent;
- Lau, Yee Ling
Publication type:
Article
CYP2D6 genotyping in paediatric patients with autism treated with risperidone: a preliminary cohort study.
Published in:
Developmental Medicine & Child Neurology, 2014, v. 56, n. 10, p. 990, doi. 10.1111/dmcn.12470
By:
- Youngster, Ilan;
- Zachor, Ditza A;
- Gabis, Lidia V;
- Bar‐Chaim, Adina;
- Benveniste‐Levkovitz, Patricia;
- Britzi, Malka;
- Soback, Stefan;
- Ziv‐Baran, Tomer;
- Berkovitch, Matitiahu
Publication type:
Article
Association between CYP2D6 phenotype and recurrence of Plasmodium vivax infection in south Korean patients.
Published in:
Malaria Journal, 2022, v. 21, n. 1, p. 1, doi. 10.1186/s12936-022-04311-6
By:
- Choi, Sungim;
- Choi, Heun;
- Park, Seong Yeon;
- Kwak, Yee Gyung;
- Song, Je Eun;
- Shin, So Youn;
- Baek, Ji Hyeon;
- Shin, Hyun-IL;
- Cho, Shin-Hyung;
- Lee, Sang-Eun;
- Kwon, Jeong-Ran;
- Park, Sookkyung;
- Kim, Miyoung;
- Oh, Hong Sang;
- Kim, Yong Chan;
- Kim, Min Jae;
- Yeom, Joon-Sup
Publication type:
Article
A single low dose of primaquine is safe and sufficient to reduce transmission of Plasmodium falciparum gametocytes regardless of cytochrome P450 2D6 enzyme activity in Bagamoyo district, Tanzania.
Published in:
Malaria Journal, 2022, v. 21, n. 1, p. 1, doi. 10.1186/s12936-022-04100-1
By:
- Mwaiswelo, Richard Owden;
- Ngasala, Billy;
- Msolo, Dominick;
- Kweka, Eliningaya;
- Mmbando, Bruno P.;
- Mårtensson, Andreas
Publication type:
Article
Effect of the allelic variants of ABCB1, CYP2D6 and HTR3B on response of ramosetron to prevent chemotherapy-induced nausea and vomiting in Korean cancer patients.
Published in:
Asia Pacific Journal of Clinical Oncology, 2017, v. 13, n. 1, p. 53, doi. 10.1111/ajco.12575
By:
- Kang, Gaeun;
- Kim, Ka‐Rham;
- Shim, Hyun‐Jeong;
- Hwang, Jun‐Eul;
- Bae, Woo‐Kyun;
- Chung, Ik‐Joo;
- Kim, Hee‐Nam;
- Lee, Jongtae;
- Choi, Kyungmee;
- Shin, Hee‐Young;
- Kim, Jong‐Keun;
- Jeong, Seong‐Wook;
- Cho, Sang‐Hee
Publication type:
Article
Rational Molecular Design of a Fluorescent Probe for Selectively Sensing Human Cytochrome P450 2D6.
Published in:
Angewandte Chemie, 2024, v. 136, n. 41, p. 1, doi. 10.1002/ange.202409217
By:
- Ning, Jing;
- Tian, Zhenhao;
- Wang, Jiayue;
- Yan, Fei;
- Shi, Chao;
- Zhang, Shujing;
- Feng, Lei;
- Shu, Xiaohong;
- Cui, Jingnan;
- James, Tony D.;
- Ma, Xiaochi
Publication type:
Article
Current status of the analytical validation of next generation sequencing applications for pharmacogenetic profiling.
Published in:
Molecular Biology Reports, 2023, v. 50, n. 11, p. 9587, doi. 10.1007/s11033-023-08748-z
By:
- Huebner, Tatjana;
- Steffens, Michael;
- Scholl, Catharina
Publication type:
Article
Characterizing the Effect of Cytochrome P450 (CYP) 2C8, CYP2C9, and CYP2D6 Genetic Polymorphisms on Stereoselective N-demethylation of Fluoxetine.
Published in:
Chirality, 2014, v. 26, n. 3, p. 166, doi. 10.1002/chir.22289
By:
- Wang, Zhangting;
- Wang, Shengjia;
- Huang, Minmin;
- Hu, Haihong;
- Yu, Lushan;
- Zeng, Su
Publication type:
Article
Association between BRCA mutations and endometrial carcinoma: a systematic review with meta-analysis.
Published in:
2021
By:
- Lu, Guojiao;
- Lu, Tao;
- Pan, Jichen;
- Guo, Ling;
- Pang, Yingxin;
- Liu, Peishu
Publication type:
journal article
Review: Influence of the CYP450 Genetic Variation on the Treatment of Psychotic Disorders.
Published in:
Journal of Clinical Medicine, 2021, v. 10, n. 18, p. 4275, doi. 10.3390/jcm10184275
By:
- Carrascal-Laso, Lorena;
- Isidoro-García, María;
- Ramos-Gallego, Ignacio;
- Franco-Martín, Manuel A.
Publication type:
Article
Adverse Drug Reactions in the Emergency Department: Is There a Role for Pharmacogenomic Profiles at Risk?—Results from the ADRED Study.
Published in:
Journal of Clinical Medicine, 2020, v. 9, n. 6, p. 1801, doi. 10.3390/jcm9061801
By:
- Just, Katja S.;
- Dormann, Harald;
- Schurig, Marlen;
- Böhme, Miriam;
- Fracowiak, Jochen;
- Steffens, Michael;
- Scholl, Catharina;
- Seufferlein, Thomas;
- Gräff, Ingo;
- Schwab, Matthias;
- Stingl, Julia C.
Publication type:
Article
Pharmacogenetic testing of CYP2D6, CYP2C19 and CYP2C9 in Denmark: Agreement between publicly funded genotyping tests and the subsequent phenotype classification.
Published in:
Basic & Clinical Pharmacology & Toxicology, 2024, v. 134, n. 5, p. 756, doi. 10.1111/bcpt.13990
By:
- Houlind, Morten Baltzer;
- Hansen, Luise;
- Iversen, Esben;
- Rasmussen, Henrik Berg;
- Larsen, Jens Borggaard;
- Jørgensen, Steffen;
- Dalhoff, Kim;
- Damkier, Per;
- Walls, Anne B.;
- Vermehren, Charlotte;
- Andersen, Trine Rune Høgh;
- Kallemose, Thomas;
- Christrup, Lona;
- Westergaard, Niels
Publication type:
Article
Effect of CYP2D6 genotype on duloxetine serum concentration.
Published in:
Basic & Clinical Pharmacology & Toxicology, 2024, v. 134, n. 1, p. 186, doi. 10.1111/bcpt.13954
By:
- Hole, Kristine;
- Gangsø, Sofie;
- Jensstuen, Åsa Tonette;
- Ormøy, Hanne Holte;
- Paulsen, Maren;
- Molden, Espen;
- Haslemo, Tore
Publication type:
Article