Works matching DE "CYTOCHROME P-450 CYP2D6"

Results: 519

Tramadol: keep calm and carry on.

Published in:

2017

By:

Anderson, Brian J.;
Thomas, Jane;
Ottaway, Kaye;
Chalkiadis, George A.

Publication type:

Editorial

Metabolic ratios and SNPs implicated in tramadol-related deaths.

Published in:

International Journal of Legal Medicine, 2023, v. 137, n. 5, p. 1431, doi. 10.1007/s00414-023-03052-8

By:

Aly, Sanaa M.;
Hakim, Florian;
Richeval, Camille;
Hennart, Benjamin;
Gaulier, Jean-michel;
Allorge, Delphine

Publication type:

Article

Exploring the 1000 Genomes Project haplotype reporting for the CYP2D6 pharmacogene.

Published in:

2019

By:

Wendt, Frank R.;
Woerner, August E.;
Sajantila, Antti;
Moura-Neto, Rodrigo S.;
Budowle, Bruce

Publication type:

Letter to the Editor

Full-gene haplotypes refine CYP2D6 metabolizer phenotype inferences.

Published in:

International Journal of Legal Medicine, 2018, v. 132, n. 4, p. 1007, doi. 10.1007/s00414-017-1709-0

By:

Wendt, Frank R.;
Woerner, August E.;
Budowle, Bruce;
Sajantila, Antti;
Moura-Neto, Rodrigo S.

Publication type:

Article

The Effect of Flavonoid Aglycones on the CYP1A2, CYP2A6, CYP2C8 and CYP2D6 Enzymes Activity.

Published in:

Molecules, 2019, v. 24, n. 17, p. 3174, doi. 10.3390/molecules24173174

By:

Bojić, Mirza;
Kondža, Martin;
Rimac, Hrvoje;
Benković, Goran;
Maleš, Željan

Publication type:

Article

SMARTCyp 3.0: enhanced cytochrome P450 site-of-metabolism prediction server.

Published in:

Bioinformatics, 2019, v. 35, n. 17, p. 3174, doi. 10.1093/bioinformatics/btz037

By:

Olsen, Lars;
Montefiori, Marco;
Tran, Khanhvi Phuc;
Jørgensen, Flemming Steen

Publication type:

Article

Identification of the effects of pathogenic genetic variations of human CYP2C9 and CYP2D6: an in silico approach.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2024, v. 43, n. 4, p. 356, doi. 10.1080/15257770.2023.2262519

By:

Avsar, Orcun

Publication type:

Article

CBD-oil as a potential solution in case of severe tamoxifen-related side effects.

Published in:

NPJ Breast Cancer, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41523-023-00570-x

By:

Buijs, Sanne M.;
Braal, C. Louwrens;
Buck, Stefan A. J.;
van Maanen, Noud F.;
van der Meijden-Erkelens, Lonneke M.;
Kuijper-Tissot van Patot, Heleen A.;
Hoop, Esther Oomen-de;
Saes, Lotte;
van den Boogerd, Sophia J.;
Struik, Liesbeth E. M.;
van Rossum-Schornagel, Quirine C.;
Mathijssen, Ron H. J.;
Koolen, Stijn L. W.;
Jager, Agnes

Publication type:

Article

valuation of the inhibition performance of pyrrole derivatives against CYP450 isoforms.

Published in:

Pharmacia (0428-0296), 2024, v. 71, n. 1, p. 1, doi. 10.3897/pharmacia.71.e122067

By:

Kondeva-Burdina, Magdalena;
Mateev, Emilio;
Irfan, Ali;
Kuteva, Hristina;
Georgieva, Maya

Publication type:

Article

Frequency of CYP2D63 and 4 and metabolizer phenotypes in three mestizo Peruvian populations.

Published in:

Pharmacia (0428-0296), 2021, v. 68, n. 4, p. 891, doi. 10.3897/pharmacia.68.e75165

By:

Alvarado, Angel T.;
Ybañez-Julca, Roberto;
María Muñoz, Ana;
Tejada-Bechi, César;
Cerro, Roberto;
Abel Quiñones, Luis;
Varela, Nelson;
Alvarado, César André;
Alvarado, Erick;
Bendezú, María R.;
García, Jorge A.

Publication type:

Article

Influence of endoxifen on mammographic density: results from the KARISMA-Tam trial.

Published in:

JNCI: Journal of the National Cancer Institute, 2025, v. 117, n. 4, p. 629, doi. 10.1093/jnci/djae280

By:

Hammarström, Mattias;
Gabrielson, Marike;
Bergqvist, Jenny;
Lundholm, Cecilia;
Crippa, Alessio;
Bäcklund, Magnus;
Wengström, Yvonne;
Borgquist, Signe;
Eliasson, Erik;
Eriksson, Mikael;
Tapia, José;
Czene, Kamila;
Hall, Per

Publication type:

Article

Loss of Heterozygosity at the CYP2D6 Locus in Breast Cancer: Implications for Tamoxifen Pharmacogenetic Studies.

Published in:

2015

By:

Johnson, Julie A.;
Hamadeh, Issam S.;
Langaee, Taimour Y.

Publication type:

Editorial

Re: Concordance Between CYP2D6 Genotypes Obtained From Tumor-Derived and Germline DNA.

Published in:

2014

By:

BERRY, DONALD A.

Publication type:

Letter to the Editor

Re: Concordance Between CYP2D6 Genotypes Obtained From Tumor-Derived and Germline DNA.

Published in:

2014

By:

RAE, JAMES M.;
LEYLAND-JONES, BRIAN;
REGAN, MEREDITH

Publication type:

Letter to the Editor

Re: Concordance Between CYP2D6 Genotypes Obtained From Tumor-Derived and Germline DNA.

Published in:

2014

By:

GOETZ, MATTHEW P.;
BRAUCH, HILTRUD;
RATAIN, MARK J.;
COX, NANCY J.;
NAKAMURA, YUSUKE;
WEINSHILBOUM, RICHARD;
INGLE, JAMES N.

Publication type:

Letter to the Editor

Variantes alélicas de CYP2D6: 3, 4, 5 y 6 en pacientes con enfermedad de Huntington residentes en el municipio de Juan de Acosta, Atlántico (Colombia).

Published in:

Revista Colombiana de Ciencias Químico-Farmacéuticas, 2023, v. 52, n. 2, p. 720, doi. 10.15446/rcciquifa.v52n2.104393

By:

García Cuan, Aracely del Carmen;
Flórez Cifuentes, Jennifer Andrea;
Macías Puente, María Fernanda;
Navarro Navarro, Jaime Antonio;
Rondón González, Fernando

Publication type:

Article

MDMA (3,4-Methylenedioxy-Mmethamphetamine) and Cannabis Intake Resulting in Multiple Organ Failure, Hypoglycemia, Disseminated Intravascular Coagulation (DIC), and Methemoglobinemia.

Published in:

Asia Pacific Journal of Medical Toxicology, 2021, v. 10, n. 4, p. 154

By:

ALTINTAS, EMEL;
CEHRELİ, ONUR BARIŞ;
SAVRAN, YUSUF;
BAYRAM, BASAK

Publication type:

Article

MDMA pharmacokinetics: A population and physiologically based pharmacokinetics model‐informed analysis.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 2, p. 376, doi. 10.1002/psp4.13282

By:

Huestis, Marilyn A.;
Smith, William B.;
Leonowens, Cathrine;
Blanchard, Rebecca;
Viaccoz, Aurélien;
Spargo, Erin;
Miner, Nicholas B.;
Yazar‐Klosinski, Berra

Publication type:

Article

Physiologically‐based pharmacokinetic modeling of quinidine to establish a CYP3A4, P‐gp, and CYP2D6 drug–drug–gene interaction network.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2023, v. 12, n. 8, p. 1143, doi. 10.1002/psp4.12981

By:

Feick, Denise;
Rüdesheim, Simeon;
Marok, Fatima Zahra;
Selzer, Dominik;
Loer, Helena Leonie Hanae;
Teutonico, Donato;
Frechen, Sebastian;
van der Lee, Maaike;
Moes, Dirk Jan A. R.;
Swen, Jesse J.;
Schwab, Matthias;
Lehr, Thorsten

Publication type:

Article

Prediction of CYP‐mediated DDIs involving inhibition: Approaches to address the requirements for system qualification of the Simcyp Simulator.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2022, v. 11, n. 7, p. 822, doi. 10.1002/psp4.12794

By:

Kilford, Peter J.;
Chen, Kuan‐Fu;
Crewe, Kim;
Gardner, Iain;
Hatley, Oliver;
Ke, Alice Ban;
Neuhoff, Sibylle;
Zhang, Mian;
Rowland Yeo, Karen

Publication type:

Article

Physiologically‐based pharmacokinetic modeling of dextromethorphan to investigate interindividual variability within CYP2D6 activity score groups.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2022, v. 11, n. 4, p. 494, doi. 10.1002/psp4.12776

By:

Rüdesheim, Simeon;
Selzer, Dominik;
Fuhr, Uwe;
Schwab, Matthias;
Lehr, Thorsten

Publication type:

Article

Cytochrome P450 2D6 genotype–phenotype characterization through population pharmacokinetic modeling of tedatioxetine.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2021, v. 10, n. 9, p. 983, doi. 10.1002/psp4.12635

By:

Frederiksen, Trine;
Areberg, Johan;
Schmidt, Ellen;
Stage, Tore Bjerregaard;
Brøsen, Kim

Publication type:

Article

Genetic prediction of antihyperglycemic drug targets and risk of epilepsy: a mendelian randomisation study.

Published in:

BMC Pharmacology & Toxicology, 2024, v. 25, n. 1, p. 1, doi. 10.1186/s40360-023-00718-2

By:

Zhou, Kaiping;
Yang, Huan;
Xie, Zhihao;
Wang, Weiping;
Qu, Zhenzhen

Publication type:

Article

Bupropion Increased More than Five Times the Systemic Exposure to Aripiprazole: An In Vivo Study in Wistar albino Rats.

Published in:

Metabolites (2218-1989), 2024, v. 14, n. 11, p. 588, doi. 10.3390/metabo14110588

By:

Ciocotișan, Iulia-Maria;
Muntean, Dana Maria;
Vlase, Laurian

Publication type:

Article

The Evaluation of CYP2D6, CYP2C9, CYP2C19 , and CYP2B6 Phenoconversion in Post-Mortem Casework: The Challenge of Forensic Toxicogenetics.

Published in:

Metabolites (2218-1989), 2023, v. 13, n. 5, p. 661, doi. 10.3390/metabo13050661

By:

Giorgetti, Arianna;
Amurri, Sara;
Fazio, Giulia;
Bini, Carla;
Anniballi, Laura;
Pirani, Filippo;
Pelletti, Guido;
Pelotti, Susi

Publication type:

Article

Optimising Fluvoxamine Maternal/Fetal Exposure during Gestation: A Pharmacokinetic Virtual Clinical Trials Study.

Published in:

Metabolites (2218-1989), 2022, v. 12, n. 12, p. 1281, doi. 10.3390/metabo12121281

By:

Burhanuddin, Khairulanwar;
Badhan, Raj

Publication type:

Article

Categorization of Cytochrome P4502D6 Activity Score by Urinary Amphetamine/Methamphetamine Ratios.

Published in:

Metabolites (2218-1989), 2022, v. 12, n. 12, p. 1174, doi. 10.3390/metabo12121174

By:

Chaichana, Jatuporn;
Khamenkhetkarn, Manee;
Sastraruji, Thanapat;
Monum, Tawachai;
O'Brien, Timothy E.;
Amornlertwatana, Yutti;
Jaikang, Churdsak

Publication type:

Article

Pharmacogenomic testing for CYP2C19 and CYP2D6 in cyclic vomiting syndrome.

Published in:

Neurogastroenterology & Motility, 2024, v. 36, n. 1, p. 1, doi. 10.1111/nmo.14705

By:

Patel, Milan;
Partovi, Omeed;
Karrento, Katja;
Garacchi, Zhuping;
Balasubramanian, Gokulakrishnan;
Venkatesan, Thangam

Publication type:

Article

Cytochrome P450-2D6*4 polymorphism seminal relationship in infertile men.

Published in:

Andrologia, 2015, v. 47, n. 5, p. 525, doi. 10.1111/and.12298

By:

Zalata, A.;
El‐Samanoudy, A. Z.;
Osman, G.;
Elhanbly, S.;
Nada, H. A.;
Mostafa, T.

Publication type:

Article

Effects of CYP2D6 and UGT2B7 polymorphisms on pharmacokinetics of tamoxifen in Thai breast cancer patients.

Published in:

Breast Cancer: Targets & Therapy, 2013, v. 5, p. 73, doi. 10.2147/BCTT.S47172

By:

Areepium, N.;
Panomvana, D.;
Rungwanonchai, P.;
Sathaporn, S.;
Voravud, N.

Publication type:

Article

ANALYSING CYP2D6*4 ALLELE FREQUENCY IN PATIENTS WITH SCHIZOPHRENIA.

Published in:

Acta Medica Medianae, 2022, v. 61, n. 4, p. 18, doi. 10.5633/amm.2022.0403

By:

Djordjević, Vladimir V.;
Stoimenov, Tatjana Jevtović

Publication type:

Article

Molecular Evolution of the CYP2D Subfamily in Primates: Purifying Selection on Substrate Recognition Sites without the Frequent or Long-Tract Gene Conversion.

Published in:

Genome Biology & Evolution, 2015, v. 7, n. 4, p. 1053, doi. 10.1093/gbe/evv056

By:

Yoshiki Yasukochi;
Yoko Satta

Publication type:

Article

Nanopore sequencing-based genotyping suggested an association between CYP2D6 function and susceptibility to anxiety and depression.

Published in:

BMC Research Notes, 2025, v. 18, n. 1, p. 1, doi. 10.1186/s13104-025-07156-9

By:

Chua, Eng Wee;
Karunanathie, Harsheni;
Yanasegaran, Kevina;
Maggo, Simran;
Kee, Ping Siu;
Kennedy, Martin;
Abdul Manaf, Mohd Rizal;
Ng, Pei Yuen

Publication type:

Article

托莫西汀在注意力缺陷多动障碍患儿中的精准药学研究： CYP2D6 基因检测和治疗药物监测

Published in:

Chinese Journal of Contemporary Pediatrics, 2023, v. 25, n. 1, p. 98, doi. 10.7499/j.issn.1008-8830.2208092

By:

符迪;
郭宏丽;
胡雅慧;
综述;
陈峰;
审校

Publication type:

Article

A Study on CYP2C19 and CYP2D6 Polymorphic Effects on Pharmacokinetics and Pharmacodynamics of Amitriptyline in Healthy Koreans.

Published in:

CTS: Clinical & Translational Science, 2017, v. 10, n. 2, p. 93, doi. 10.1111/cts.12451

By:

Ryu, S;
Park, S;
Lee, JH;
Kim, YR;
Na, HS;
Lim, HS;
Choi, HY;
Hwang, IY;
Lee, JG;
Park, ZW;
Oh, WY;
Kim, JM;
Choi, SE

Publication type:

Article

CYP2D6 genotyping and use of antidepressants in breast cancer patients: test development for clinical application.

Published in:

Metabolic Brain Disease, 2012, v. 27, n. 3, p. 319, doi. 10.1007/s11011-012-9312-z

By:

van der Merwe, Nicole;
Bouwens, Christianne;
Pienaar, Rika;
van der Merwe, Lize;
Yako, Yandiswa;
Geiger, Dieter;
Kotze, Maritha

Publication type:

Article

Cytochrome P450 2D6 and Parkinson's Disease: Polymorphism, Metabolic Role, Risk and Protection.

Published in:

Neurochemical Research, 2017, v. 42, n. 12, p. 3353, doi. 10.1007/s11064-017-2384-8

By:

ur Rasheed, Mohd;
Mishra, Abhishek;
Singh, Mahendra

Publication type:

Article

CYP2D6 EXPRESSION IS CUMULATIVELY UP REGULATED IN MULTIDRUG TREATED HEPATOMA CELLS: A PREDECTIVE PHARMACOGENETICS IN VITRO MODEL.

Published in:

Egyptian Journal of Biochemistry & Molecular Biology, 2020, v. 38, n. 1/2, p. 39

By:

Khedr, Sherine;
Donia, Thoria;
Salim, Elsayed Ibrahim;
Hessien, Mohamed

Publication type:

Article

Functional phenotyping of the CYP2D6 probe drug codeine in the horse.

Published in:

BMC Veterinary Research, 2021, v. 17, n. 1, p. 1, doi. 10.1186/s12917-021-02788-y

By:

Gretler, S. R.;
Finno, C. J.;
Kass, P. H.;
Knych, H. K.

Publication type:

Article

Effect of the allelic variants of ABCB1, CYP2D6 and HTR3B on response of ramosetron to prevent chemotherapy-induced nausea and vomiting in Korean cancer patients.

Published in:

Asia Pacific Journal of Clinical Oncology, 2017, v. 13, n. 1, p. 53, doi. 10.1111/ajco.12575

By:

Kang, Gaeun;
Kim, Ka‐Rham;
Shim, Hyun‐Jeong;
Hwang, Jun‐Eul;
Bae, Woo‐Kyun;
Chung, Ik‐Joo;
Kim, Hee‐Nam;
Lee, Jongtae;
Choi, Kyungmee;
Shin, Hee‐Young;
Kim, Jong‐Keun;
Jeong, Seong‐Wook;
Cho, Sang‐Hee

Publication type:

Article

Cas9 targeted nanopore sequencing with enhanced variant calling improves CYP2D6-CYP2D7 hybrid allele genotyping.

Published in:

PLoS Genetics, 2022, v. 18, n. 9, p. 1, doi. 10.1371/journal.pgen.1010176

By:

Rubben, Kaat;
Tilleman, Laurentijn;
Deserranno, Koen;
Tytgat, Olivier;
Deforce, Dieter;
Van Nieuwerburgh, Filip

Publication type:

Article

Transfer learning enables prediction of CYP2D6 haplotype function.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 11, p. 1, doi. 10.1371/journal.pcbi.1008399

By:

McInnes, Gregory;
Dalton, Rachel;
Sangkuhl, Katrin;
Whirl-Carrillo, Michelle;
Lee, Seung-been;
Tsao, Philip S.;
Gaedigk, Andrea;
Altman, Russ B.;
Woodahl, Erica L.

Publication type:

Article

Inhibitory Mechanisms of Lekethromycin in Dog Liver Cytochrome P450 Enzymes Based on UPLC-MS/MS Cocktail Method.

Published in:

Molecules, 2023, v. 28, n. 20, p. 7193, doi. 10.3390/molecules28207193

By:

Sun, Pan;
Cao, Yuying;
Qiu, Jicheng;
Kong, Jingyuan;
Zhang, Suxia;
Cao, Xingyuan

Publication type:

Article

Cancers du sein.

Published in:: Oncologie (Tech Science Press), 2012, v. 14, n. 6/7, p. 398, doi. 10.1007/s10269-012-2183-4
Publication type:: Article

Bouffées de chaleur, tamoxifène et cytochrome P450 2D6.

Published in:

Oncologie (Tech Science Press), 2012, v. 14, n. 6/7, p. 357, doi. 10.1007/s10269-012-2170-9

By:

Boutet, G.

Publication type:

Article

POLIMORFIZMY GENETYCZNE A EFEKTY METABOLICZNE DZIAŁANIA OLANZAPINY.

Published in:

State & Society / Państwo i Społeczeństwo, 2023, v. 23, n. 1, p. 151, doi. 10.48269/2451-0858-pis-2023-1-011

By:

Sadakierska-Chudy, Anna;
Bartosiewicz, Angelika

Publication type:

Article

Evaluation of herb-drug interaction of Withania somnifera with anti-rheumatic drugs through high-throughput screening.

Published in:

Journal of Research in Pharmacy, 2022, v. 26, n. 2, p. 334, doi. 10.29228/jrp.131

By:

KANJILAL, Satyajyoti;
GUPTA, Ashok Kumar;
PATNAİK, Ranjana;
DEY, Amitabha;
MOHAPATRA, Satyabrata

Publication type:

Article

Pyrazine-chromene-3-carbohydrazide conjugates: Molecular docking and ADMET predictions on dualacting compounds against SARS-CoV-2 M<sup>pro</sup> and RdRp.

Published in:

Journal of Research in Pharmacy, 2021, v. 25, n. 6, p. 953, doi. 10.29228/jrp.92

By:

MERMER, Arif;
VAKAL, Serhii

Publication type:

Article

INTERACTION OF NEW POTENTIAL ANTIMICROBIAL COMPOUNDS WITH PORCINE MICROSOMAL CYP2D.

Published in:

2022

By:

Špičáková, Alena;
Horáčková, Zuzana;
Kopel, Pavel;
Anzenbacherová, Eva;
Anzenbacher, Pavel

Publication type:

Abstract

Urinary Pharmacokinetics of Immediate and Controlled Release Oxycodone and its Phase I and II Metabolites Using LC–MS-MS.

Published in:

Journal of Analytical Toxicology, 2022, v. 46, n. 9, p. 1025, doi. 10.1093/jat/bkab123

By:

Truver, Michael T;
Jakobsson, Gerd;
Chermà, Maria D;
Swortwood, Madeleine J;
Gréen, Henrik;
Kronstrand, Robert

Publication type:

Article