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Advancements in physiologically based pharmacokinetic modeling for fedratinib: updating dose guidance in the presence of a dual inhibitor of CYP3A4 and CYP2C19.
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- Cancer Chemotherapy & Pharmacology, 2024, v. 94, n. 4, p. 549, doi. 10.1007/s00280-024-04696-y
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- Article
Combined effect of CYP2C19 and CYP2D6 genotypes on escitalopram serum concentration and its metabolic ratio in a European patient population.
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- British Journal of Clinical Pharmacology, 2024, v. 90, n. 10, p. 2630, doi. 10.1111/bcp.16156
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- Article
Development and validation of next-generation sequencing panel for personalized Helicobacter pylori eradication treatment targeting multiple species.
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- Frontiers in Cellular & Infection Microbiology, 2024, p. 1, doi. 10.3389/fcimb.2024.1379790
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- Article
Pharmacogenomics in Psychiatry: An Asian Perspective.
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- 2024
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- Abstract
Precision Antiplatelet Therapy after Percutaneous Coronary Intervention (Precision PCI) Registry – Informing optimal antiplatelet strategies.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 8, p. 1, doi. 10.1111/cts.70004
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- Article
The Frequency of CYP2C19 Loss-of-Function Variants in Patients with Non-Cardioembolic Ischemic Stroke or Transient Ischemic Attack in the Dutch Population.
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- Cerebrovascular Diseases, 2023, v. 52, n. 6, p. 700, doi. 10.1159/000529892
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- Article
Relationship between CYP2C19 Polymorphism and Clopidogrel Resistance in Patients with Coronary Heart Disease and Ischemic Stroke in China.
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- Genetics Research, 2022, p. 1, doi. 10.1155/2022/1901256
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- Article
Investigation of Radiotracer Metabolic Stability In Vitro with CYP-Overexpressing Hepatoma Cell Lines.
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- Cells (2073-4409), 2022, v. 11, n. 15, p. 2447, doi. 10.3390/cells11152447
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- Article
From genes to drugs: CYP2C19 and pharmacogenetics in clinical practice.
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- Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1326776
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- Article
The influence of CYP2C19 polymorphisms on voriconazole trough concentrations: Systematic review and meta‐analysis.
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- Mycoses, 2021, v. 64, n. 8, p. 860, doi. 10.1111/myc.13293
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- Article
Rates of Divergent Pharmacogenes in a Psychiatric Cohort of Inpatients with Depression—Arguments for Preemptive Testing.
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- Journal of Xenobiotics, 2022, v. 12, n. 4, p. 317, doi. 10.3390/jox12040022
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- Article
Effects of CYP2C19 variants on the metabolism of tapentadol in vitro.
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- Iranian Journal of Basic Medical Sciences, 2022, v. 25, n. 5, p. 659, doi. 10.22038/IJBMS.2022.56996.12710
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- Article
Potential of Anethum graveolens L. to up-regulate the expression of phase I and II metabolizing genes in HepG2 cells.
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- Tropical Journal of Pharmaceutical Research, 2021, v. 20, n. 12, p. 2519, doi. 10.4314/tjpr.v20i12.9
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- Article
Analysis of CYP2C19 Gene Genotype in Patients with Acute Cerebral Infarction and Its Relationship with Disease Progression.
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- Russian Journal of Genetics, 2023, v. 59, n. 10, p. 1092, doi. 10.1134/S1022795423100083
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- Article
Distribution of the cytochrome P450 *alleles for CYP2C9 and CYP2C19 in a cohort of the Danish Blood Donor Study determined by using the Illumina Infinium Global Screening Array.
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- Basic & Clinical Pharmacology & Toxicology, 2024, v. 135, n. 2, p. 217, doi. 10.1111/bcpt.14040
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- Article
Pharmacogenetic testing of CYP2D6, CYP2C19 and CYP2C9 in Denmark: Agreement between publicly funded genotyping tests and the subsequent phenotype classification.
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- Basic & Clinical Pharmacology & Toxicology, 2024, v. 134, n. 5, p. 756, doi. 10.1111/bcpt.13990
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- Article
Drug metabolism and drug transport of the 100 most prescribed oral drugs.
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- Basic & Clinical Pharmacology & Toxicology, 2022, v. 131, n. 5, p. 311, doi. 10.1111/bcpt.13780
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- Article
Ticagrelor is more effective than clopidogrel in carrier of nonfunctional CYP2C19 allele who has diabetes and acute coronary syndrome - case report and literature review.
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- AIMS Molecular Science, 2022, v. 9, n. 2, p. 66, doi. 10.3934/molsci.2022004
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- Article
Determining The Enhancing Effects Of PCR Additives On Long- Range PCR.
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- 2022
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- Publication type:
- Abstract
The efficacy of clopidogrel in preventing recurrent cardiovascular events among Arab population carrying different CYP2C19 mutations: systematic review and meta-analysis.
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- Egyptian Journal of Medical Human Genetics, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s43042-022-00313-w
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- Article
Identification of pharmacogenetic variants from large scale next generation sequencing data in the Saudi population.
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- PLoS ONE, 2022, v. 17, n. 1, p. 1, doi. 10.1371/journal.pone.0263137
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- Article
Cost-effectiveness of testing for CYP2C19 loss-of-function carriers following transient ischemic attack/minor stroke: A Canadian perspective.
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- International Journal of Stroke, 2023, v. 18, n. 4, p. 416, doi. 10.1177/17474930221111898
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- Article
A Conserved Allosteric Site on Drug-Metabolizing CYPs: A Systematic Computational Assessment.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 24, p. 13215, doi. 10.3390/ijms222413215
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- Article
Association with CYP2C19 polymorphisms and Clopidogrel in treatment of elderly stroke patients.
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- BMC Neurology, 2021, v. 21, n. 1, p. 1, doi. 10.1186/s12883-021-02127-6
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- Article
Distribution of CYP2C19, ABCB1 and PON1 polymorphisms in Chinese Han, Hui, Uygur and Kazak patients with coronary atherosclerotic heart disease.
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- International Journal of Immunogenetics, 2020, v. 47, n. 6, p. 539, doi. 10.1111/iji.12511
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- Article
Prevalence of CYP2C9 and CYP2C19 variants and the impact on clopidogrel efficacy in patients having CYPC19*2 variant.
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- Indian Journal of Pharmacology, 2023, v. 55, n. 1, p. 27, doi. 10.4103/ijp.ijp_706_22
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- Article
The CYP2C19 genotypes and its effect on clopidogrel as an anti-platelet drug among the Arab population.
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- Indian Journal of Pharmacology, 2021, v. 53, n. 1, p. 85, doi. 10.4103/ijp.IJP_690_20
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- Article
The impact of CYP2C19 genotypes on steady-state plasma concentration of escitalopram in South Indian population with Major Depressive Disorder.
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- Pharmacia (0428-0296), 2024, v. 71, n. 1, p. 1, doi. 10.3897/pharmacia.71.e123645
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- Article
Systematic review of economic evaluation studies in psychiatric pharmacogenomics.
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- European Psychiatry, 2021, v. 64, p. S382, doi. 10.1192/j.eurpsy.2021.1024
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- Article
Analysis of the effect of CYP2C19 gene properties on the anti-platelet aggregation of clopidogrel after carotid artery stenting under network pharmacology.
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- BMC Pharmacology & Toxicology, 2024, v. 25, n. 1, p. 1, doi. 10.1186/s40360-024-00750-w
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- Article
Effectiveness of vonoprazan-based regimens compared with proton pump inhibitor-based regimens as first-line Helicobacter pylori agents.
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- Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1216433
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- Article
The impact of CYP2C19 genotype on phenoconversion by concomitant medication.
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- Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1201906
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- Article
From gene to dose: Long-read sequencing and *-allele tools to refine phenotype predictions of CYP2C19.
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- Frontiers in Pharmacology, 2023, v. 14, p. 01, doi. 10.3389/fphar.2023.1076574
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- Article
The pharmacogenetics of CYP2D6 and CYP2C19 in a case series of antidepressant responses.
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- Frontiers in Pharmacology, 2023, v. 14, p. 1, doi. 10.3389/fphar.2023.1080117
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- Article
Personalized antiplatelet therapy guided by clopidogrel pharmacogenomics in acute ischemic stroke and transient ischemic attack: A prospective, randomized controlled trial.
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- Frontiers in Pharmacology, 2023, v. 14, p. 1, doi. 10.3389/fphar.2022.931405
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- Article
Comprehensive in vitro and in silico assessments of metabolic capabilities of 24 genomic variants of CYP2C19 using two different substrates.
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- Frontiers in Pharmacology, 2023, v. 13, p. 1, doi. 10.3389/fphar.2023.1055991
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- Article
Consideration of the Medical Economics of Cardiac Genetics, Focusing on the Cost-Effectiveness of P2Y12 Inhibitor Selection Based on the CYP2C19 Loss-of-Function Allele: A Semi-Systematic Review.
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- Cardiogenetics, 2024, v. 14, n. 2, p. 59, doi. 10.3390/cardiogenetics14020005
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- Article
Genetic Polymorphism of CYP2C19 in Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention (PCI) in Erbil.
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- Journal of Pharmaceutical Negative Results, 2022, v. 13, n. 4, p. 377, doi. 10.47750/pnr.2022.13.04.046
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- Article
Electrochemical Biosensor for Detection of the CYP2C19*2 Allele Based on Exonuclease Ⅲ.
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- Micromachines, 2023, v. 14, n. 3, p. 541, doi. 10.3390/mi14030541
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- Article
Is CYP2C Haplotype Relevant for Efficacy and Bleeding Risk in Clopidogrel-Treated Patients?
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- Genes, 2024, v. 15, n. 5, p. 607, doi. 10.3390/genes15050607
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- Article
CYP2D6 and CYP2C19 Variant Coverage of Commercial Antidepressant Pharmacogenomic Testing Panels Available in Victoria, Australia.
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- Genes, 2023, v. 14, n. 10, p. 1945, doi. 10.3390/genes14101945
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- Article
Implementation of Pharmacogenetics in First-Line Care: Evaluation of Its Use by General Practitioners.
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- Genes, 2023, v. 14, n. 10, p. 1841, doi. 10.3390/genes14101841
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- Article
Feasibility of Community Pharmacist-Initiated and Point-of-Care CYP2C19 Genotype-Guided De-Escalation of Oral P2Y12 Inhibitors.
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- Genes, 2023, v. 14, n. 3, p. 578, doi. 10.3390/genes14030578
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- Article
The Influence of CYP2D6 and CYP2C19 Genetic Variation on Diabetes Mellitus Risk in People Taking Antidepressants and Antipsychotics.
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- Genes, 2021, v. 12, n. 11, p. 1758, doi. 10.3390/genes12111758
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- Article
Perioperative platelet reactivity over time in patients undergoing vascular surgery: An observational pilot study.
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- PLoS ONE, 2024, v. 19, n. 6, p. 1, doi. 10.1371/journal.pone.0304800
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- Article
Pharmacogenomics knowledge within Neurology: A brief survey amongst physicians.
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- Neurology Asia, 2023, v. 28, n. 4, p. 943, doi. 10.54029/2023xfs
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- Article
Physiologically Based Pharmacokinetic Modeling to Unravel the Drug-gene Interactions of Venlafaxine: Based on Activity Score-dependent Metabolism by CYP2D6 and CYP2C19 Polymorphisms.
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- Pharmaceutical Research, 2024, v. 41, n. 4, p. 731, doi. 10.1007/s11095-024-03680-8
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- Article
Prediction of Omeprazole Pharmacokinetics and its Inhibition on Gastric Acid Secretion in Humans Using Physiologically Based Pharmacokinetic-Pharmacodynamic Model Characterizing CYP2C19 Polymorphisms.
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- Pharmaceutical Research, 2023, v. 40, n. 7, p. 1735, doi. 10.1007/s11095-023-03531-y
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- Article
Physiologically Based Pharmacokinetic Modeling for Multiple Oral Administration Labetalol in Pregnant Women.
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- Pharmaceutical Research, 2023, v. 40, n. 7, p. 1765, doi. 10.1007/s11095-023-03523-y
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- Article
Microdialysis of Voriconazole and its N-Oxide Metabolite: Amalgamating Knowledge of Distribution and Metabolism Processes in Humans.
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- Pharmaceutical Research, 2022, v. 39, n. 12, p. 3279, doi. 10.1007/s11095-022-03407-7
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- Article