Works matching DE "CYTIDINE deaminase"

Results: 405

Characterization of RNA editing gene APOBEC3C as a candidate tumor suppressor in prostate cancer.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-00169-1

By:

Wang, Li-Yang;
Shi, Ji;
Wang, Mo-Fei;
Liu, Yi-Meng;
Guo, Hong-Shan;
Wang, Jin-Cheng;
Jiang, Shu;
Liang, Jia-Qian;
Liao, Xing-Hua;
Chen, Shao-Yong

Publication type:

Article

Excessive activation-induced cytidine deaminase accumulated by proteasome inhibitors rescues abnormal class switch in activated B-cell-like diffuse large B-cell lymphoma.

Published in:

Experimental & Therapeutic Medicine, 2025, v. 29, n. 6, p. N.PAG, doi. 10.3892/etm.2025.12863

By:

Lv, Zhuangwei;
Xu, Chen;
Wang, Zhenzhen;
Liu, Zixian;
Jiao, Junna

Publication type:

Article

Function analysis of the cytidine deaminases in root-knot nematode, Meloidogyne incognita.

Published in:

European Journal of Plant Pathology, 2025, v. 172, n. 1, p. 43, doi. 10.1007/s10658-024-02983-1

By:

Wang, Dongwei;
Wang, Jian;
Li, Yingmei;
Zhang, Zhuo;
Cheng, Jue;
Zhu, Chunhui;
Zhao, Zhixiang;
Tan, Xinqiu;
Zhang, Deyong;
Liu, Yong;
Cheng, Feixue

Publication type:

Article

Cellular Defense Enzyme Drives Exceptionally High Rate of Mutation in HIV.

Published in:

PLoS Biology, 2015, v. 13, n. 9, p. 1, doi. 10.1371/journal.pbio.1002252

By:

Robinson, Richard

Publication type:

Article

Pan-cancer landscape of AID-related mutations, composite mutations, and their potential role in the ICI response.

Published in:

NPJ Precision Oncology, 2022, v. 6, n. 1, p. 1, doi. 10.1038/s41698-022-00331-2

By:

Hernández-Verdin, Isaias;
Akdemir, Kadir C.;
Ramazzotti, Daniele;
Caravagna, Giulio;
Labreche, Karim;
Mokhtari, Karima;
Hoang-Xuan, Khê;
Peyre, Matthieu;
Bielle, Franck;
Touat, Mehdi;
Idbaih, Ahmed;
Duval, Alex;
Sanson, Marc;
Alentorn, Agustí

Publication type:

Article

A small molecule iCDM-34 identified by in silico screening suppresses HBV DNA through activation of aryl hydrocarbon receptor.

Published in:

Cell Death Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41420-023-01755-w

By:

Furutani, Yutaka;
Hirano, Yoshinori;
Toguchi, Mariko;
Higuchi, Shoko;
Qin, Xian-Yang;
Yanaka, Kaori;
Sato-Shiozaki, Yumi;
Takahashi, Nobuaki;
Sakai, Marina;
Kongpracha, Pornparn;
Suzuki, Takehiro;
Dohmae, Naoshi;
Kukimoto-Niino, Mutsuko;
Shirouzu, Mikako;
Nagamori, Shushi;
Suzuki, Harukazu;
Kobayashi, Kaoru;
Masaki, Takahiro;
Koyama, Hiroo;
Sekiba, Kazuma

Publication type:

Article

Activation-induced cytidine deaminase expression in patients with myelodysplastic syndrome and its relationship with prognosis and treatment.

Published in:

Turkish Journal of Medical Sciences, 2021, v. 51, n. 5, p. 2451, doi. 10.3906/sag-2101-81

By:

TORUN, Ege Sinan;
DAĞLAR ADAY, Aynur;
NALÇACI, Meliha

Publication type:

Article

Targeting mutagenesis in B cells: Phosphorylation goes beyond AID association.

Published in:

Molecular & Cellular Oncology, 2018, v. 5, n. 5, p. 1, doi. 10.1080/23723556.2018.1432259

By:

Mu, Yunxiang;
McBride, Kevin M.

Publication type:

Article

Novel mutations in hyper‐IgM syndrome type 2 and X‐linked agammaglobulinemia detected in three patients with primary immunodeficiency disease.

Published in:

Molecular Genetics & Genomic Medicine, 2021, v. 9, n. 1, p. 1, doi. 10.1002/mgg3.1552

By:

Chen, Xihui;
Liu, Fangfang;
Yuan, Lijuan;
Zhang, Meng;
Chen, Kun;
Wu, Yuanming

Publication type:

Article

Melanoma's high C> T mutation rate: is deamination playing a role?

Published in:

Experimental Dermatology, 2014, v. 23, n. 8, p. 551, doi. 10.1111/exd.12436

By:

Sanchez, Margaret I.;
Grichnik, James M.

Publication type:

Article

Expression of AID in malignant melanoma with BRAF<sup>V600E</sup> mutation.

Published in:

Experimental Dermatology, 2014, v. 23, n. 5, p. 347, doi. 10.1111/exd.12402

By:

Okura, Risa;
Yoshioka, Haruna;
Yoshioka, Manabu;
Hiromasa, Kana;
Nishio, Daisuke;
Nakamura, Motonobu

Publication type:

Article

A new technique for the analysis of metabolic pathways of cytidine analogues and cytidine deaminase activities in cells.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-47792-4

By:

Ligasová, Anna;
Piskláková, Barbora;
Friedecký, David;
Koberna, Karel

Publication type:

Article

B cell-specific knockout of AID protects against atherosclerosis.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-35980-1

By:

Ebrahimian, Talin;
Dierick, France;
Ta, Vincent;
Kotsiopriftis, Maria;
O'Connor Miranda, Jonathan;
Mann, Koren K.;
Orthwein, Alexandre;
Lehoux, Stephanie

Publication type:

Article

Highly Efficient CRISPR-Mediated Base Editing in Sinorhizobium meliloti.

Published in:

Frontiers in Microbiology, 2021, v. 12, p. 1, doi. 10.3389/fmicb.2021.686008

By:

Wang, Longxiang;
Xiao, Yuan;
Wei, Xiaowei;
Pan, Jimin;
Duanmu, Deqiang

Publication type:

Article

Mutating for Good: DNA Damage Responses During Somatic Hypermutation.

Published in:

Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.00438

By:

Pilzecker, Bas;
Jacobs, Heinz

Publication type:

Article

Circulating Follicular Helper and Follicular Regulatory T Cells Are Severely Compromised in Human CD40 Deficiency: A Case Report.

Published in:

2018

By:

Cicalese, Maria Pia;
Gerosa, Jolanda;
Baronio, Manuela;
Montin, Davide;
Licciardi, Francesco;
Soresina, Annarosa;
Dellepiane, Rosa Maria;
Miano, Maurizio;
Baselli, Lucia Augusta;
Volpi, Stefano;
Dufour, Carlo;
Plebani, Alessandro;
Aiuti, Alessandro;
Lougaris, Vassilios;
Fousteri, Georgia

Publication type:

Case Study

Diversity in the Cow Ultralong CDR H3 Antibody Repertoire.

Published in:

Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.01262

By:

Haakenson, Jeremy K.;
Huang, Ruiqi;
Smider, Vaughn V.

Publication type:

Article

Genomic Characteristics and Its Therapeutic Implications in Breast Cancer Patients with Detectable Molecular Residual Disease.

Published in:

Cancer Research & Treatment, 2024, v. 56, n. 2, p. 538, doi. 10.4143/crt.2023.1059

By:

Zhang, Shu;
Jiang, Yan;
Zhou, Lu;
Xu, Jing;
Zhang, Gang;
Shen, Lu;
Xu, Yan

Publication type:

Article

A Cas3-base editing tool for targetable in vivo mutagenesis.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-39087-z

By:

Zimmermann, Anna;
Prieto-Vivas, Julian E.;
Cautereels, Charlotte;
Gorkovskiy, Anton;
Steensels, Jan;
Van de Peer, Yves;
Verstrepen, Kevin J.

Publication type:

Article

Bacteroides-derived isovaleric acid enhances mucosal immunity by facilitating intestinal IgA response in broilers.

Published in:

Journal of Animal Science & Biotechnology, 2023, v. 14, n. 1, p. 1, doi. 10.1186/s40104-022-00807-y

By:

Wang, Xinkai;
Hu, Yifan;
Zhu, Xiaoyan;
Cai, Liyuan;
Farooq, Muhammad Zahid;
Yan, Xianghua

Publication type:

Article

Family Functioning, Social Support and Depression in a Chinese Population.

Published in:

Psychopathology, 2012, v. 45, n. 5, p. 334, doi. 10.1159/000336218

By:

Wang, Jikun;
Zhao, Xudong;
Liu, Liang;
Ma, Xiquan

Publication type:

Article

Creation of zebularine-resistant human cytidine deaminase mutants to enhance the chemoprotection of hematopoietic stem cells.

Published in:

PEDS: Protein Engineering, Design & Selection, 2016, v. 29, n. 12, p. 573, doi. 10.1093/protein/gzw012

By:

Hongmei Ruan;
Songbo Qiu;
Beard, Brian C.;
Black, Margaret E.

Publication type:

Article

Evidence for etiologic field changes in tongue distant from tumor in patients with squamous cell carcinoma of the oral tongue.

Published in:

Journal of Pathology, 2023, v. 259, n. 1, p. 93, doi. 10.1002/path.6025

By:

Gu, Xiaolian;
Wang, Lixiao;
Coates, Philip J;
Gnanasundram, Sivakumar Vadivel;
Sgaramella, Nicola;
Sörlin, Jonas;
Erdogan, Baris;
Magan, Mustafa;
Nylander, Karin

Publication type:

Article

Presence of Human Papillomavirus (HPV) Apolipoprotein B Messenger RNA Editing, Catalytic Polypeptide-Like 3 (APOBEC)-Related Minority Variants in HPV-16 Genomes From Anal and Cervical Samples but Not in HPV-52 and HPV-58.

Published in:

2018

By:

Mariaggi, Alice-Andrée;
Péré, Hélène;
Perrier, Marine;
Visseaux, Benoit;
Collin, Gilles;
Veyer, David;
Hingrat, Quentin Le;
Ferré, Valentine Marie;
Joly, Véronique;
Couvelard, Anne;
Le Hingrat, Quentin;
Bucau, Margot;
Davitian, Carine;
Descamps, Diane;
Abramowitz, Laurent;
Charpentier, Charlotte

Publication type:

journal article

Targeted C•G-to-T•A base editing with TALE-cytosine deaminases in plants.

Published in:

BMC Biology, 2024, v. 22, n. 1, p. 1, doi. 10.1186/s12915-024-01895-0

By:

Zhang, Dingbo;
Pries, Vanessa;
Boch, Jens

Publication type:

Article

Ancestral reconstruction reveals catalytic inactivation of activation-induced cytidine deaminase concomitant with cold water adaption in the Gadiformes bony fish.

Published in:

BMC Biology, 2022, v. 20, n. 1, p. 1, doi. 10.1186/s12915-022-01489-8

By:

Ghorbani, Atefeh;
Khataeipour, S. Javad;
Solbakken, Monica H.;
Huebert, David N. G.;
Khoddami, Minasadat;
Eslamloo, Khalil;
Collins, Cassandra;
Hori, Tiago;
Jentoft, Sissel;
Rise, Matthew L.;
Larijani, Mani

Publication type:

Article

Selective treatment pressure in colon cancer drives the molecular profile of resistant circulating tumor cell clones.

Published in:

2021

By:

Cayrefourcq, Laure;
Thomas, Frédéric;
Mazard, Thibault;
Assenat, Eric;
Assou, Said;
Alix-Panabières, Catherine

Publication type:

Letter

Highly-potent, synthetic APOBEC3s restrict HIV-1 through deamination-independent mechanisms.

Published in:

PLoS Pathogens, 2021, v. 17, n. 6, p. 1, doi. 10.1371/journal.ppat.1009523

By:

McDonnell, Mollie M.;
Karvonen, Suzanne C.;
Gaba, Amit;
Flath, Ben;
Chelico, Linda;
Emerman, Michael

Publication type:

Article

Structural features of antiviral DNA cytidine deaminases.

Published in:

Biological Chemistry, 2013, v. 394, n. 11, p. 1357, doi. 10.1515/hsz-2013-0165

By:

Vasudevan, Ananda Ayyappan Jaguva;
Smits, Sander H.J.;
Höppner, Astrid;
Häussinger, Dieter;
Koenig, Bernd W.;
Münk, Carsten

Publication type:

Article

Parasite biology: Malaria alters B cell lymphomagenesis.

Published in:

Nature Reviews Microbiology, 2015, v. 13, n. 10, p. 602, doi. 10.1038/nrmicro3555

By:

Kugelberg, Elisabeth

Publication type:

Article

Oral tetrahydrouridine and decitabine for non-cytotoxic epigenetic gene regulation in sickle cell disease: A randomized phase 1 study.

Published in:

2017

By:

Molokie, Robert;
Lavelle, Donald;
Gowhari, Michel;
Pacini, Michael;
Krauz, Lani;
Hassan, Johara;
Ibanez, Vinzon;
Ruiz, Maria A.;
Ng, Kwok Peng;
Woost, Philip;
Radivoyevitch, Tomas;
Pacelli, Daisy;
Fada, Sherry;
Rump, Matthew;
Hsieh, Matthew;
Tisdale, John F.;
Jacobberger, James;
Phelps, Mitch;
Engel, James Douglas;
Saraf, Santhosh

Publication type:

journal article

A compact Cas9 ortholog from Staphylococcus Auricularis (SauriCas9) expands the DNA targeting scope.

Published in:

PLoS Biology, 2020, v. 18, n. 3, p. 1, doi. 10.1371/journal.pbio.3000686

By:

Hu, Ziying;
Wang, Shuai;
Zhang, Chengdong;
Gao, Ning;
Li, Miaomiao;
Wang, Deqian;
Wang, Daqi;
Liu, Dong;
Liu, Huihui;
Ong, Sang-Ging;
Wang, Hongyan;
Wang, Yongming

Publication type:

Article

Engineering herbicide-resistant watermelon variety through CRISPR/Cas9-mediated base-editing.

Published in:

Plant Cell Reports, 2018, v. 37, n. 9, p. 1353, doi. 10.1007/s00299-018-2299-0

By:

Tian, Shouwei;
Jiang, Linjian;
Cui, Xiaxia;
Zhang, Jie;
Guo, Shaogui;
Li, Maoying;
Zhang, Haiying;
Ren, Yi;
Gong, Guoyi;
Zong, Mei;
Liu, Fan;
Chen, Qijun;
Xu, Yong

Publication type:

Article

Synthesis and Biological Evaluation of PEGylated MWO 4 Nanoparticles as Sonodynamic AID Inhibitors in Treating Diffuse Large B-Cell Lymphoma.

Published in:

Molecules, 2022, v. 27, n. 21, p. 7143, doi. 10.3390/molecules27217143

By:

Jiao, Junna;
Qian, Zhuang;
Wang, Yurong;
Liu, Mei;
Fan, Liye;
Liu, Mengqing;
Hao, Zichen;
Jiao, Junrong;
Lv, Zhuangwei

Publication type:

Article

Synthesis of Sugar and Nucleoside Analogs and Evaluation of Their Anticancer and Analgesic Potentials.

Published in:

Molecules, 2022, v. 27, n. 11, p. 3499, doi. 10.3390/molecules27113499

By:

Hussain, Fahad;
Rahman, Fahad Imtiaz;
Saha, Poushali;
Mikami, Atsushi;
Osawa, Takashi;
Obika, Satoshi;
Rahman, S. M. Abdur

Publication type:

Article

Anti-HIV Activities and Mechanism of 12-O-Tricosanoylphorbol-20-acetate, a Novel Phorbol Ester from Ostodes katharinae.

Published in:

Molecules, 2017, v. 22, n. 9, p. 1498, doi. 10.3390/molecules22091498

By:

Huan Chen;
Rong Zhang;
Rong-Hua Luo;
Liu-Meng Yang;
Rui-Rui Wang;
Xiao-Jiang Hao;
Yong-Tang Zheng

Publication type:

Article

Highly efficient base editing in bacteria using a Cas9-cytidine deaminase fusion.

Published in:

Communications Biology, 2018, v. 1, n. 1, p. N.PAG, doi. 10.1038/s42003-018-0035-5

By:

Zheng, Ke;
Wang, Yang;
Li, Na;
Jiang, Fang-Fang;
Wu, Chang-Xian;
Liu, Fang;
Chen, Huan-Chun;
Liu, Zheng-Fei

Publication type:

Article

Production of an active human AID enzyme in a bacterial system.

Published in:

Biotechnologia, 2016, v. 97, n. 3, p. 235, doi. 10.5114/bta.2016.62360

By:

BUDZKO, LUCYNA;
JACKOWIAK, PAULINA;
FIGLEROWICZ, MAREK

Publication type:

Article

Protein kinase Cδ is essential for the IgG response against T-cell-independent type 2 antigens and commensal bacteria.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.72116

By:

Saori Fukao;
Kei Haniuda;
Hiromasa Tamaki;
Daisuke Kitamura

Publication type:

Article

Relationship between BCL2 mutations and follicular lymphoma outcome in the chemoimmunotherapy era.

Published in:

Blood Cancer Journal, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41408-023-00847-1

By:

Correia, Cristina;
Maurer, Matthew J.;
McDonough, Samantha J.;
Schneider, Paula A.;
Ross, Paige E.;
Novak, Anne J.;
Feldman, Andrew L.;
Cerhan, James R.;
Slager, Susan L.;
Witzig, Thomas E.;
Eckloff, Bruce W.;
Li, Hu;
Nowakowski, Grzegorz S.;
Kaufmann, Scott H.

Publication type:

Article

Sustained high expression of multiple APOBEC3 cytidine deaminases in systemic lupus erythematosus.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-87024-1

By:

Perez-Bercoff, Danielle;
Laude, Hélène;
Lemaire, Morgane;
Hunewald, Oliver;
Thiers, Valérie;
Vignuzzi, Marco;
Blanc, Hervé;
Poli, Aurélie;
Amoura, Zahir;
Caval, Vincent;
Suspène, Rodolphe;
Hafezi, François;
Mathian, Alexis;
Vartanian, Jean-Pierre;
Wain-Hobson, Simon

Publication type:

Article

Activation-induced cytidine deaminase is a possible regulator of cross-talk between oocytes and granulosa cells through GDF-9 and SCF feedback system.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-83529-x

By:

Iizuka, Takashi;
Wakae, Kousho;
Ono, Masanori;
Suzuki, Takuma;
Mizumoto, Yasunari;
Kitamura, Kouichi;
Horike, Shin-ichi;
Muramatsu, Masamichi;
Fujiwara, Hiroshi

Publication type:

Article

Multiple gene substitution by Target-AID base-editing technology in tomato.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-77379-2

By:

Hunziker, Johan;
Nishida, Keiji;
Kondo, Akihiko;
Kishimoto, Sanae;
Ariizumi, Tohru;
Ezura, Hiroshi

Publication type:

Article

Activation-induced cytidine deaminase overexpression in double-hit lymphoma: potential target for novel anticancer therapy.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-71058-y

By:

Zhang, Jingcheng;
Shi, Yifen;
Zhao, Mingzhe;
Hu, Huixian;
Huang, He

Publication type:

Article

A decrease in NAMPT activity impairs basal PARP-1 activity in cytidine deaminase deficient-cells, independently of NAD<sup>+</sup>.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-70874-6

By:

Silveira, Sandra Cunha;
Buhagiar-Labarchède, Géraldine;
Onclercq-Delic, Rosine;
Gemble, Simon;
Bou Samra, Elias;
Mameri, Hamza;
Duchambon, Patricia;
Machon, Christelle;
Guitton, Jérôme;
Amor-Guéret, Mounira

Publication type:

Article

High efficiency CHO cell display-based antibody maturation.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-65044-7

By:

Luo, Ruiqi;
Zhao, Yun;
Fan, Yingjun;
An, Lili;
Jiang, Tao;
Ma, Shaohua;
Hang, Haiying

Publication type:

Article

Generation of Transfer-DNA-Free Base-Edited Citrus Plants.

Published in:

Frontiers in Plant Science, 2022, v. 13, p. 1, doi. 10.3389/fpls.2022.835282

By:

Alquézar, Berta;
Bennici, Stefania;
Carmona, Lourdes;
Gentile, Alessandra;
Peña, Leandro

Publication type:

Article

Activation induced cytidine deaminase: An old friend with new faces.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.965312

By:

Çakan, Elif;
Gunaydin, Gurcan

Publication type:

Article

Switch Tandem Repeats Influence the Choice of the Alternative End-Joining Pathway in Immunoglobulin Class Switch Recombination.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.870933

By:

Oudinet, Chloé;
Zhang, Xuefei;
Puget, Nadine;
Kyritsis, Nia;
Leduc, Claire;
Braikia, Fatima-Zohra;
Dauba, Audrey;
Alt, Frederick W.;
Khamlichi, Ahmed Amine

Publication type:

Article

Aberrantly Activated APOBEC3B Is Associated With Mutant p53-Driven Refractory/Relapsed Diffuse Large B-Cell Lymphoma.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.888250

By:

Zhang, Xuzhao;
Wu, Zhaoxing;
Hao, Yuanyuan;
Yu, Teng;
Li, Xian;
Liang, Yun;
Li, Jinfan;
Huang, Liansheng;
Xu, Yang;
Li, Xiuzhen;
Xu, Xiaohua;
Wang, Weiqin;
Xu, Genbo;
Zhang, Xiaohong;
Lv, Qinghua;
Fang, Yongming;
Xu, Rongzhen;
Qian, Wenbin

Publication type:

Article