Works matching DE "CYSTATHIONINE"

Results: 177

Cystathionine-β-Synthase Inhibition for Colon Cancer: Enhancement of the Efficacy of Aminooxyacetic Acid via the Prodrug Approach.

Published in:

Molecular Medicine, 2016, v. 22, n. 1, p. 361, doi. 10.2119/molmed.2016.00102

By:

Chao, Celia;
Zatarain, John R;
Ding, Ye;
Coletta, Ciro;
Mrazek, Amy A;
Druzhyna, Nadiya;
Johnson, Paul;
Chen, Haiying;
Hellmich, Judy L;
Asimakopoulou, Antonia;
Yanagi, Kazunori;
Olah, Gabor;
Szoleczky, Petra;
Törö, Gabor;
Bohanon, Fredrick J;
Cheema, Minal;
Lewis, Rachel;
Eckelbarger, David;
Ahmad, Akbar;
Módis, Katalin

Publication type:

Article

Screening of Heteroaromatic Scaffolds against Cystathionine Beta-Synthase Enables Identification of Substituted Pyrazolo[3,4-c]Pyridines as Potent and Selective Orthosteric Inhibitors.

Published in:

Molecules, 2020, v. 25, n. 16, p. 3739, doi. 10.3390/molecules25163739

By:

Fantel, Anna-Maria;
Myrianthopoulos, Vassilios;
Georgoulis, Anastasios;
Lougiakis, Nikolaos;
Zantza, Iliana;
Lamprinidis, George;
Augsburger, Fiona;
Marakos, Panagiotis;
Vorgias, Constantinos E.;
Szabo, Csaba;
Pouli, Nicole;
Papapetropoulos, Andreas;
Mikros, Emmanuel;
Salvador, Jorge A.R.

Publication type:

Article

Analysis of Total Thiols in the Urine of a Cystathionine β-Synthase-Deficient Mouse Model of Homocystinuria Using Hydrophilic Interaction Chromatography.

Published in:

Molecules, 2020, v. 25, n. 7, p. 1735, doi. 10.3390/molecules25071735

By:

Chang, Chun-Fang;
Hamase, Kenji;
Tsunoda, Makoto

Publication type:

Article

Hydrogen Sulfide and Polysulfides as Biological Mediators.

Published in:

Molecules, 2014, v. 19, n. 10, p. 16146, doi. 10.3390/molecules191016146

By:

Hideo Kimura

Publication type:

Article

The Reliable Detection of Homocysteine Using a Biosensor Based on Recombinant Cystathionine β-Synthase and Nanoporous Gold.

Published in:

Microorganisms, 2025, v. 13, n. 3, p. 559, doi. 10.3390/microorganisms13030559

By:

Huang, Zihan;
Gao, Yan;
Zhang, Lei;
Cai, Ting;
Liu, Ruijun;
Wang, Xia

Publication type:

Article

Gut Microbiota and Metabolome Changes in Three Pulmonary Hypertension Rat Models.

Published in:

Microorganisms, 2023, v. 11, n. 2, p. 472, doi. 10.3390/microorganisms11020472

By:

Luo, Lingjie;
Yin, Haoyang;
Gou, Deming

Publication type:

Article

Simultaneous analysis of free amino acids and taurine-related compounds in deep-sea mussel tissues using reversed-phase HPLC.

Published in:

Fisheries Science, 2018, v. 84, n. 1, p. 127, doi. 10.1007/s12562-017-1143-8

By:

Nagasaki, Toshihiro;
Koito, Tomoko;
Nemoto, Suguru;
Ushio, Hideki;
Inoue, Koji

Publication type:

Article

L-cystathionine inhibits oxidized low density lipoprotein-induced THP-1-derived macrophage inflammatory cytokine monocyte chemoattractant protein-1 generation via the NF-κB pathway.

Published in:

Scientific Reports, 2015, p. 10453, doi. 10.1038/srep10453

By:

Zhu, Mingzhu;
Jin, Hongfang;
Du, Junbao;
Liu, Angie Dong;
Holmberg, Lukas;
Chen, Selena Y;
Bu, Dingfang;
Tang, Chaoshu

Publication type:

Article

Obsessive-Compulsive Symptoms as a Manifestation of Homocystinuria.

Published in:

Case Reports in Psychiatry, 2021, p. 1, doi. 10.1155/2021/5523453

By:

Froes, Vera;
Afonso, Hugo;
Gameiro, Zita

Publication type:

Article

Architecture and regulation of filamentous human cystathionine beta-synthase.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-46864-x

By:

McCorvie, Thomas J.;
Adamoski, Douglas;
Machado, Raquel A. C.;
Tang, Jiazhi;
Bailey, Henry J.;
Ferreira, Douglas S. M.;
Strain-Damerell, Claire;
Baslé, Arnaud;
Ambrosio, Andre L. B.;
Dias, Sandra M. G.;
Yue, Wyatt W.

Publication type:

Article

SAM, a cystathionine beta-synthase activator, promotes hydrogen sulfide to promote neural repair resulting from massive cerebral infarction induced by middle cerebral artery occlusion.

Published in:

Metabolic Brain Disease, 2022, v. 37, n. 5, p. 1641, doi. 10.1007/s11011-022-00976-9

By:

Wang, Fang;
Zhou, Hao;
Zhang, Xiaoxia

Publication type:

Article

Impaired PLP-dependent metabolism in brain samples from Huntington disease patients and transgenic R6/1 mice.

Published in:

Metabolic Brain Disease, 2016, v. 31, n. 3, p. 579, doi. 10.1007/s11011-015-9777-7

By:

Sorolla, M.;
Rodríguez-Colman, María;
Vall-llaura, Núria;
Vived, Celia;
Fernández-Nogales, Marta;
Lucas, José;
Ferrer, Isidre;
Cabiscol, Elisa

Publication type:

Article

Dynamic Change of Hydrogen Sulfide After Traumatic Brain Injury and its Effect in Mice.

Published in:

Neurochemical Research, 2013, v. 38, n. 4, p. 714, doi. 10.1007/s11064-013-0969-4

By:

Zhang, Mingyang;
Shan, Haiyan;
Wang, Tao;
Liu, Weili;
Wang, Yaoqi;
Wang, Long;
Zhang, Lu;
Chang, Pan;
Dong, Wenwen;
Chen, Xiping;
Tao, Luyang

Publication type:

Article

Crystal Structure of the Pyridoxal 5′-phosphate Dependent L-Methionine γ-Lyase from Pseudomonas putida.

Published in:

Journal of Biochemistry, 2000, v. 128, n. 3, p. 349, doi. 10.1093/oxfordjournals.jbchem.a022760

By:

Motoshima, Hiroyuki;
Inagaki, Kenji;
Kumasaka, Takashi;
Furuichi, Makio;
Inoue, Hiroyuki;
Tamura, Takashi;
Esaki, Nobuyoshi;
Soda, Kenji;
Tanaka, Nobuo;
Yamamoto, Masaki;
Tanaka, Hidehiko

Publication type:

Article

6-Bromoindole- and 6-Bromoindazole-Based Inhibitors of Bacterial Cystathionine γ-Lyase Containing 3-Aminothiophene-2-Carboxylate Moiety.

Published in:

Molecules, 2025, v. 30, n. 2, p. 388, doi. 10.3390/molecules30020388

By:

Novikov, Roman A.;
Platonov, Dmitry N.;
Belyy, Alexander Yu.;
Potapov, Konstantin V.;
Novikov, Maxim A.;
Tomilov, Yury V.;
Kechko, Olga I.;
Seregina, Tatiana A.;
Zemskaya, Anastasia S.;
Solyev, Pavel N.;
Mitkevich, Vladimir A.

Publication type:

Article

Synthesis of the Indole-Based Inhibitors of Bacterial Cystathionine γ-Lyase NL1-NL3.

Published in:

Molecules, 2023, v. 28, n. 8, p. 3568, doi. 10.3390/molecules28083568

By:

Potapov, Konstantin V.;
Novikov, Roman A.;
Novikov, Maxim A.;
Solyev, Pavel N.;
Tomilov, Yury V.;
Kochetkov, Sergey N.;
Makarov, Alexander A.;
Mitkevich, Vladimir A.

Publication type:

Article

CysK from Lactobacillus casei encodes a protein with O-acetylserine sulfhydrylase and cysteine desulfurization activity.

Published in:

Applied Microbiology & Biotechnology, 2012, v. 94, n. 5, p. 1209, doi. 10.1007/s00253-011-3677-5

By:

Bogicevic, Biljana;
Berthoud, Hélène;
Portmann, Reto;
Meile, Leo;
Irmler, Stefan

Publication type:

Article

Biochemical and structural impact of two novel missense mutations in cystathionine γ-synthase gene associated with homocystinuria.

Published in:

Biochemical Journal, 2024, v. 481, n. 8, p. 569, doi. 10.1042/BCJ20240012

By:

Al-Sadeq, Duaa W.;
Conter, Carolina;
Thanassoulas, Angelos;
Al-Dewik, Nader;
Safieh-Garabedian, Bared;
Martínez-Cruz, Luis Alfonso;
Nasrallah, Gheyath K.;
Astegno, Alessandra;
Nomikos, Michail

Publication type:

Article

Using RNA-Seq Analysis to Select Key Genes Related to Seed Dormancy in ALS-Inhibiting Resistant Descurainia sophia with Pro-197-Thr Mutation.

Published in:

Plants (2223-7747), 2024, v. 13, n. 16, p. 2305, doi. 10.3390/plants13162305

By:

Xu, Xian;
Zhao, Bochui;
Shen, Beibei;
Qi, Zhizun;
Wang, Jianping;
Cui, Haiyan;
Li, Binghua;
Chen, Silong;
Wang, Guiqi;
Liu, Xiaomin

Publication type:

Article

Corrigendum: Genome-wide identification of genes encoding cystathionine beta synthase domain-containing proteins in wheat and its relationship with anther male sterility under heat stress.

Published in:

Frontiers in Plant Science, 2023, p. 1, doi. 10.3389/fpls.2023.1198918

By:

Hongzhan Liu;
Qi Wang;
Liuyong Xie;
Kedong Xu;
Fuli Zhang;
Xianle Ruan;
Lili Li;
Guangxuan Tan

Publication type:

Article

Genome-wide identification of genes encoding cystathionine beta synthase domaincontaining proteins in wheat and its relationship with anther male sterility under heat stress.

Published in:

Frontiers in Plant Science, 2023, p. 1, doi. 10.3389/fpls.2022.1061472

By:

Hongzhan Liu;
Qi Wang;
Liuyong Xie;
Kedong Xu;
Fuli Zhang;
Xianle Ruan;
Lili Li;
Guangxuan Tan

Publication type:

Article

Genome-wide identification of cystathionine beta synthase genes in wheat and its relationship with anther male sterility under heat stress.

Published in:

Frontiers in Plant Science, 2022, v. 13, p. 01, doi. 10.3389/fpls.2022.1061472

By:

Hongzhan Liu;
Qi Wang;
Liuyong Xie;
Kedong Xu;
Fuli Zhang;
Xianle Ruan;
Lili Li;
Guangxuan Tan

Publication type:

Article

Benserazide, a cystathionine beta-synthase (CBS) inhibitor, potentially enhances the anticancer effects of paclitaxel via inhibiting the S-sulfhydration of SIRT1 and the HIF1-α/VEGF pathway.

Published in:

Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1404532

By:

Wei Zhao;
Shasha Feng;
Jian Wang;
Zhenshuai Zhang;
Lu Chen;
Li Jiang;
Ming Li;
Tianxiao Wang

Publication type:

Article

Neonatal Colonic Inflammation Increases Spinal Transmission and Cystathionine β-Synthetase Expression in Spinal Dorsal Horn of Rats with Visceral Hypersensitivity.

Published in:

Frontiers in Pharmacology, 2017, p. 1, doi. 10.3389/fphar.2017.00696

By:

Liting Zhao;
Ying Xiao;
Rui-Xia Weng;
Xuelian Liu;
Ping-An Zhang;
Chuang-Ying Hu;
Yu, Shan P.;
Guang-Yin Xu

Publication type:

Article

3-Mercaptopyruvate Sulfurtransferase, Not Cystathionine β-Synthase Nor Cystathionine γ-Lyase, Mediates Hypoxia-Induced Migration of Vascular Endothelial Cells.

Published in:

Frontiers in Pharmacology, 2017, p. 1, doi. 10.3389/fphar.2017.00657

By:

Beibei Tao;
Rui Wang;
Chen Sun;
Yichun Zhu

Publication type:

Article

Involvement of NF‐κB in the upregulation of cystathionine‐γ‐lyase, a hydrogen sulfide‐forming enzyme, and bladder pain accompanying cystitis in mice.

Published in:

Clinical & Experimental Pharmacology & Physiology, 2018, v. 45, n. 4, p. 355, doi. 10.1111/1440-1681.12875

By:

Ozaki, Tomoka;
Tsubota, Maho;
Sekiguchi, Fumiko;
Kawabata, Atsufumi

Publication type:

Article

Metabolomic profiling and stable isotope labelling of Trichomonas vaginalis and Tritrichomonas foetus reveal major differences in amino acid metabolism including the production of 2-hydroxyisocaproic acid, cystathionine and S-methylcysteine.

Published in:

PLoS ONE, 2017, v. 12, n. 12, p. 1, doi. 10.1371/journal.pone.0189072

By:

Westrop, Gareth D.;
Wang, Lijie;
Blackburn, Gavin J.;
Zhang, Tong;
Zheng, Liang;
Watson, David G.;
Coombs, Graham H.

Publication type:

Article

The Effect of Certain Conditions in the Regulation of Cystathionine γ-Lyase by Exogenous Hydrogen Sulfide in Mammalian Cells.

Published in:

Biochemical Genetics, 2013, v. 51, n. 7/8, p. 503, doi. 10.1007/s10528-013-9581-1

By:

Wang, Maoxian;
Guo, Zhanyun;
Wang, Shilong

Publication type:

Article

Cystathionine β-synthase expression correlates with tumor development and poor prognosis in lung squamous cell carcinoma patients.

Published in:

Neoplasma, 2022, v. 69, n. 4, p. 868, doi. 10.4149/neo_2022_211207N1745

By:

Ya-Qing HAN;
Zi-Bo ZHANG;
Kun WANG;
Guang-Jie LIU;
Shao-Nan XIE;
Qing-Yi LIU;
Fang LIU

Publication type:

Article

Corrigendum.

Published in:: Brain Pathology, 2017, v. 27, n. 6, p. 856, doi. 10.1111/bpa.12535
Publication type:: Article

Upregulation of cystathione β-synthase and p70S6K/S6 in neonatal hypoxic ischemic brain injury.

Published in:

Brain Pathology, 2017, v. 27, n. 4, p. 449, doi. 10.1111/bpa.12421

By:

Lechpammer, Mirna;
Tran, Yen P.;
Wintermark, Pia;
Martínez‐Cerdeño, Veronica;
Krishnan, Viswanathan V.;
Ahmed, Waseem;
Berman, Robert F.;
Jensen, Frances E.;
Nudler, Evgeny;
Zagzag, David

Publication type:

Article

Promoted Interaction of Nuclear Factor-κB with Demethylated Cystathionine-β-Synthetase Gene Contributes to Gastric Hypersensitivity in Diabetic Rats.

Published in:

Journal of Neuroscience, 2013, v. 33, n. 21, p. 9028, doi. 10.1523/JNEUROSCI.1068-13.2013

By:

Zhang, Hong-Hong;
Ji Hu;
Zhou, You-Lang;
Shufen Hu;
Wang, Yong-Meng;
Wei Chen;
Ying Xiao;
Mae Huang, Li-Yen;
Xinghong Jiang;
Xu, Guang-Yin

Publication type:

Article

The transcobalamin receptor knockout mouse: a model for vitamin B12 deficiency in the central nervous system.

Published in:

FASEB Journal, 2013, v. 27, n. 6, p. 2468, doi. 10.1096/fj.12-219055

By:

Shao-Chiang Lai;
Nakayama, Yasumi;
Sequeira, Jeffrey M.;
Wlodarczyk, Bogdan J.;
Cabrera, Robert M.;
Finnell, Richard H.;
Bottiglieri, Teodoro;
Quadros, Edward V.

Publication type:

Article

Patterns of Expression of H2S-Producing Enzyme in Human Renal Cell Carcinoma Specimens: Potential Avenue for Future Therapeutics.

Published in:

In Vivo, 2020, v. 34, n. 5, p. 2775, doi. 10.21873/invivo.12102

By:

SOGUTDELEN, EMRULLAH;
PACOLI, KATHARINE;
JURIASINGANI, SMRITI;
AKBARI, MASOUD;
GABRIL, MANAL;
SENER, ALP

Publication type:

Article

The role of hydrogen sulphide in the control of breathing in hypoxic zebrafish ( Danio rerio).

Published in:

Journal of Physiology, 2014, v. 592, n. 14, p. 3075, doi. 10.1113/jphysiol.2014.271098

By:

Porteus, Cosima S.;
Abdallah, Sara J.;
Pollack, Jacob;
Kumai, Yusuke;
Kwong, Raymond W. M.;
Yew, Hong M.;
Milsom, William K.;
Perry, Steve F.

Publication type:

Article

Evidence of endogenously produced hydrogen sulfide (H2S) and persulfidation in male reproduction.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-15360-x

By:

Řimnáčová, Hedvika;
Moravec, Jiří;
Štiavnická, Miriama;
Havránková, Jiřina;
Monsef, Ladan;
Hošek, Petr;
Prokešová, Šárka;
Žalmanová, Tereza;
Fenclová, Tereza;
Petr, Jaroslav;
Králíčková, Milena;
Nevoral, Jan

Publication type:

Article

Cystathionine β-synthase affects organization of cytoskeleton and modulates carcinogenesis in colorectal carcinoma cells.

Published in:

Frontiers in Oncology, 2023, p. 1, doi. 10.3389/fonc.2023.1178021

By:

Liskova, Veronika;
Chovancova, Barbora;
Babula, Petr;
Rezuchova, Ingeborg;
Pavlov, Kristina Ploth;
Matuskova, Miroslava;
Krizanova, Olga

Publication type:

Article

Ability of Exogenous or Wort Endogenous Enzymes to Release Free Thiols from Hop Cysteinylated and Glutathionylated S-Conjugates.

Published in:

Journal of the American Society of Brewing Chemists, 2023, v. 81, n. 1, p. 33, doi. 10.1080/03610470.2021.2021766

By:

Chenot, Cécile;
Willemart, Guillaume;
Gros, Jacques;
Collin, Sonia

Publication type:

Article

Folic acid supplementation does not reduce intracellular homocysteine, and may disturb intracellular one-carbon metabolism.

Published in:

Clinical Chemistry & Laboratory Medicine, 2013, v. 51, n. 8, p. 1643, doi. 10.1515/cclm-2012-0694

By:

Smith, Desirée E. C.;
Hornstra, Jacqueline M.;
Kok, Robert M.;
Blom, Henk J.;
Smulders, Yvo M.

Publication type:

Article

New insights into the regulation of Cystathionine beta synthase (CBS), an enzyme involved in intellectual deficiency in Down syndrome.

Published in:

Frontiers in Neuroscience, 2023, v. 16, p. 1, doi. 10.3389/fnins.2022.1110163

By:

Conan, Pierre;
Léon, Alice;
Caroff, Noéline;
Rollet, Claire;
Chaïr, Loubna;
Martin, Jennifer;
Bihel, Frédéric;
Mignen, Olivier;
Voisset, Cécile;
Friocourt, Gaëlle

Publication type:

Article

The influence of cystathionine on neurochemical quantification in brain tumor in vivo MR spectroscopy.

Published in:

Magnetic Resonance in Medicine, 2022, v. 88, n. 2, p. 537, doi. 10.1002/mrm.29252

By:

Branzoli, Francesca;
Deelchand, Dinesh K.;
Liserre, Roberto;
Poliani, Pietro Luigi;
Nichelli, Lucia;
Sanson, Marc;
Lehéricy, Stéphane;
Marjańska, Małgorzata

Publication type:

Article

In vivo 1H MRS detection of cystathionine in human brain tumors.

Published in:

Magnetic Resonance in Medicine, 2019, v. 82, n. 4, p. 1259, doi. 10.1002/mrm.27810

By:

Branzoli, Francesca;
Deelchand, Dinesh K.;
Sanson, Marc;
Lehéricy, Stéphane;
Marjańska, Małgorzata

Publication type:

Article

Cystathionine β-synthase as novel endogenous regulator of lymphangiogenesis via modulating VEGF receptor 2 and 3.

Published in:

Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03923-7

By:

Hatami, Niloofar;
Büttner, Christian;
Bock, Felix;
Simfors, Sara;
Musial, Gwen;
Reis, André;
Cursiefen, Claus;
Clahsen, Thomas

Publication type:

Article

Lens subluxation in a patient with homocystinuria. Case report.

Published in:

Journal of Ophthalmology (Ukraine) / Oftalʹmologičeskij Žurnal, 2021, n. 4, p. 86, doi. 10.31288/oftalmolzh202148697

By:

Leopoldo, Garduño-Vieyra;
Bruno, Flores Escobar

Publication type:

Article

The hyperthermophilic cystathionine γ-synthase from the aerobic crenarchaeon Sulfolobus tokodaii: expression, purification, crystallization and structural insights.

Published in:

Acta Crystallographica: Section F, Structural Biology Communications, 2017, v. 73, n. 3, p. 152, doi. 10.1107/S2053230X17002011

By:

Sato, Dan;
Shiba, Tomoo;
Mizuno, Sae;
Kawamura, Ayaka;
Hanada, Shoko;
Yamada, Tetsuya;
Shinozaki, Mai;
Yanagitani, Masahiko;
Tamura, Takashi;
Inagaki, Kenji;
Harada, Shigeharu

Publication type:

Article

Purification, crystallization and preliminary crystallographic analysis of the catalytic core of cystathionine β-synthase from Saccharomyces cerevisiae.

Published in:

Acta Crystallographica: Section F, Structural Biology Communications, 2014, v. 70, n. 3, p. 320, doi. 10.1107/S2053230X14001502

By:

Ereño-Orbea, June;
Majtan, Tomas;
Oyenarte, Iker;
Kraus, Jan P.;
Martínez-Cruz, Luis Alfonso

Publication type:

Article

Association between CBS gene T833C, G919A and 844ins68 polymorphisms in the 8th exon region and coronary artery disease: a meta-analysis.

Published in:

Clinical & Experimental Hypertension, 2024, v. 46, n. 1, p. 1, doi. 10.1080/10641963.2024.2328147

By:

Zhu, Zijiang;
Geng, Yuhan;
Ma, Long;
Yao, Keying;
Chang, Ruitong;
Ma, Yongming;
Li, Jialong

Publication type:

Article

Hydrogen sulfide synthesis enzymes reduced in lower esophageal sphincter of patients with achalasia.

Published in:

Diseases of the Esophagus, 2016, v. 29, n. 7, p. 801, doi. 10.1111/dote.12385

By:

Zhang, L.;
Zhao, W.;
Zheng, Z.;
Wang, T.;
Zhao, C.;
Zhou, G.;
Jin, H.;
Wang, B.

Publication type:

Article

Oxidative damage and mitochondrial dysfunction in cystathionine beta-synthase deficiency.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-80273-w

By:

Balci, Mehmet Cihan;
Gedikbasi, Asuman;
Dogan, Sukru Anil;
Kahraman, Sevde;
Tatoryan, Suzin;
Neijmann, Sebnem Tekin;
Karaca, Meryem;
Atalar, Fatmahan;
Gokcay, Gulden

Publication type:

Article

Sulfurtransferases and Cystathionine Beta-Synthase Expression in Different Human Leukemia Cell Lines.

Published in:

Biomolecules (2218-273X), 2022, v. 12, n. 2, p. 148, doi. 10.3390/biom12020148

By:

Jurkowska, Halina;
Wróbel, Maria;
Jasek-Gajda, Ewa;
Rydz, Leszek

Publication type:

Article