Works matching DE "CYCLIN-dependent kinases"

Results: 4007

Real-world effectiveness of palbociclib plus endocrine therapy in HR+/HER2− advanced breast cancer: final results from the POLARIS trial.

Published in:

Oncologist, 2025, v. 30, n. 7, p. 1, doi. 10.1093/oncolo/oyae291

By:

Tripathy, Debu;
Blum, Joanne L;
Karuturi, Meghan S;
McCune, Steven;
Kurian, Sobha;
Moezi, Mehdi;
Anderson, Daniel;
Gauthier, Eric;
Zhang, Zhe;
Montelongo, Monica Z;
Wang, Yao;
Rocque, Gabrielle B

Publication type:

Article

A Novel Variant c.149G>A in CDK5 Gene Causing Lissencephaly Type 7.

Published in:

Clinical Genetics, 2025, v. 108, n. 3, p. 347, doi. 10.1111/cge.14748

By:

Moirangthem, Amita;
Kar, Anjana;
Sagar, Mahima;
Das, Niladri;
Maurya, Rajesh K.;
Dhakad, Ankit;
Kaur, Rupinder;
Dalal, Ashwin

Publication type:

Article

Surface functionalized albumin nanoparticles of palbociclib with amplified brain delivery for treating brain glioblastoma.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-13721-w

By:

Kurawattimath, Vishwanath;
Wilson, Barnabas;
Geetha, Kannoth Mukundan;
Divekar, Kalpana

Publication type:

Article

Ganaxolone in seizures associated with cyclin-dependent kinase-like 5 deficiency disorder: a profile of its use in the USA.

Published in:

Drugs & Therapy Perspectives, 2023, v. 39, n. 3, p. 81, doi. 10.1007/s40267-022-00976-w

By:

Keam, Susan J.;
Al-Salama, Zaina T.

Publication type:

Article

The Activation of the CCND1 Promoter by AP-1 and SOX Transcription Factors in PC3 Prostate Cancer Cells Can Be Prevented by Anacardic Acid Analogs.

Published in:

Cell Biochemistry & Biophysics, 2025, v. 83, n. 2, p. 2349, doi. 10.1007/s12013-024-01646-6

By:

Brunie, Manon;
Robichaud, Mika A.;
Touaibia, Mohamed;
Martin, Luc J.

Publication type:

Article

Overexpression of CDK5 in Neural Stem Cells Facilitates Maturation of Embryonic Neurocytes Derived from Rats In Vitro.

Published in:

Cell Biochemistry & Biophysics, 2014, v. 69, n. 3, p. 445, doi. 10.1007/s12013-014-9816-8

By:

Quan, Hongyu;
Wu, Xiyan;
Tian, Yanping;
Wang, Yun;
Li, Chengren;
Li, Hongli

Publication type:

Article

Cellular energy sensing and signaling by AMP-activated protein kinase.

Published in:

Cell Biochemistry & Biophysics, 2007, v. 47, n. 3, p. 332, doi. 10.1007/s12013-007-0008-7

By:

William Winder;
David Thomson

Publication type:

Article

Titanium Dioxide Nanoparticles Induce Cell Cycle Arrest and Apoptosis through Inhibiting PI3K/AKT/mTOR Pathway in Spermatogonia.

Published in:

Biological Trace Element Research, 2024, v. 202, n. 9, p. 4065, doi. 10.1007/s12011-023-03984-7

By:

Dong, Ruoyun;
Meng, Xiaojia;
Chang, Hongmei;
Lei, Yuzhu;
Hu, Yunhua;
Yan, Yizhong;
Song, Guanling

Publication type:

Article

Genome-wide identification and characterization of the cyclin gene family in Populus trichocarpa.

Published in:

Plant Cell, Tissue & Organ Culture, 2011, v. 107, n. 1, p. 55, doi. 10.1007/s11240-011-9957-z

By:

Dong, Qing;
Zhao, Yang;
Jiang, Haiyang;
He, Hongsheng;
Zhu, Suwen;
Cheng, Beijiu;
Xiang, Yan

Publication type:

Article

Oncogene-induced senescence in meningiomas—an immunohistochemical study.

Published in:

Journal of Neuro-Oncology, 2024, v. 166, n. 1, p. 143, doi. 10.1007/s11060-023-04532-y

By:

Mijajlović, Vladimir;
Miler, Marko;
Ilić, Rosanda;
Rašić, Dejan;
Dunđerović, Duško;
Raičević, Savo;
Soldatović, Ivan;
De Luka, Silvio;
Manojlović-Gačić, Emilija

Publication type:

Article

CBX3 promotes glioma U87 cell proliferation and predicts an unfavorable prognosis.

Published in:

Journal of Neuro-Oncology, 2019, v. 145, n. 1, p. 35, doi. 10.1007/s11060-019-03286-w

By:

Zhao, Shu-Peng;
Wang, Fan;
Yang, Ming;
Wang, Xiang-Yang;
Jin, Cai-Ling;
Ji, Qian-Kun;
Li, Shuai;
Zhao, Xin-Li

Publication type:

Article

Tumor pharmacokinetics and pharmacodynamics of the CDK4/6 inhibitor ribociclib in patients with recurrent glioblastoma.

Published in:

Journal of Neuro-Oncology, 2019, v. 144, n. 3, p. 563, doi. 10.1007/s11060-019-03258-0

By:

Miller, Todd W.;
Traphagen, Nicole A.;
Li, Jing;
Lewis, Lionel D.;
Lopes, Beatriz;
Asthagiri, Ashok;
Loomba, Johanna;
De Jong, Jenny;
Schiff, David;
Patel, Sohil H.;
Purow, Benjamin W.;
Fadul, Camilo E.

Publication type:

Article

P21Waf1/Cip1 and p27Kip1 are correlated with the development and invasion of prolactinoma.

Published in:

Journal of Neuro-Oncology, 2018, v. 136, n. 3, p. 485, doi. 10.1007/s11060-017-2683-6

By:

Dong, Wei;
Li, Jianhua;
Liu, Qian;
Liu, Chunhui;
Li, Chuzhong;
Song, Guidong;
Zhu, Haibo;
Gao, Hua;
Zhang, Yazhuo

Publication type:

Article

Phloretin induces cell cycle arrest and apoptosis of human glioblastoma cells through the generation of reactive oxygen species.

Published in:

Journal of Neuro-Oncology, 2016, v. 128, n. 2, p. 217, doi. 10.1007/s11060-016-2107-z

By:

Liu, Yuanyuan;
Fan, Chenghe;
Pu, Lv;
Wei, Cui;
Jin, Haiqiang;
Teng, Yuming;
Zhao, Mingming;
Yu, Albert;
Jiang, Feng;
Shu, Junlong;
Li, Fan;
Peng, Qing;
Kong, Jian;
Pan, Bing;
Zheng, Lemin;
Huang, Yining

Publication type:

Article

The Cdk inhibitor flavopiridol enhances temozolomide-induced cytotoxicity in human glioma cells.

Published in:

Journal of Neuro-Oncology, 2013, v. 115, n. 2, p. 169, doi. 10.1007/s11060-013-1220-5

By:

Hayashi, Takuro;
Adachi, Kazuhide;
Ohba, Shigeo;
Hirose, Yuichi

Publication type:

Article

miR-124 radiosensitizes human glioma cells by targeting CDK4.

Published in:

Journal of Neuro-Oncology, 2013, v. 114, n. 3, p. 263, doi. 10.1007/s11060-013-1179-2

By:

Deng, Xubin;
Ma, Lei;
Wu, Minhua;
Zhang, Gong;
Jin, Chuan;
Guo, Yuping;
Liu, Ruilei

Publication type:

Article

Clinical and biological significance of forkhead class box O 3a expression in glioma: mediation of glioma malignancy by transcriptional regulation of p27kip1.

Published in:

Journal of Neuro-Oncology, 2010, v. 98, n. 1, p. 57, doi. 10.1007/s11060-009-0045-8

By:

Shi, Jinlong;
Zhang, Li;
Shen, Aiguo;
Zhang, Jianguo;
Wang, Yuchan;
Zhao, Yueming;
Zou, Lin;
Ke, Qing;
He, Fei;
Wang, Ping;
Cheng, Chun;
Shi, Gongshen

Publication type:

Article

Identification of compounds with binding affinity to proteins via magnetization transfer from bulk water*.

Published in:

Journal of Biomolecular NMR, 2000, v. 18, n. 1, p. 65, doi. 10.1023/A:1008354229396

By:

Dalvit, Claudio;
Pevarello, Paolo;
Tatò, Marco;
Veronesi, Marina;
Vulpetti, Anna;
Sundström, Michael

Publication type:

Article

Geminin Interference Facilitates Vascular Smooth Muscle Cell Proliferation by Upregulation of CDK-1.

Published in:

Cardiovascular Drugs & Therapy, 2014, v. 28, n. 5, p. 407, doi. 10.1007/s10557-014-6550-9

By:

Zhang, Yuanyuan;
Jiang, Zhouqin;
Li, Linyu;
Zhou, Yeping;
Song, Zhiyuan;
Shu, Maoqin

Publication type:

Article

Real-world data on the prevalence of BRCA1/2 and HRR gene mutations in patients with primary and metastatic castration resistant prostate cancer.

Published in:

World Journal of Urology, 2024, v. 42, n. 1, p. 1, doi. 10.1007/s00345-024-05188-7

By:

Hommerding, Moritz;
Hommerding, Oliver;
Bernhardt, Marit;
Kreft, Tobias;
Sanders, Christine;
Tischler, Verena;
Basitta, Patrick;
Pelusi, Natalie;
Wulf, Anna-Lena;
Ohlmann, Carsten-Henning;
Ellinger, Jörg;
Ritter, Manuel;
Kristiansen, Glen

Publication type:

Article

Vitiligo-like lesions induced by cyclin-dependent kinase 4/ 6 inhibitor Palbociclib: a case report and literature review.

Published in:

2023

By:

Shan Gao;
Guanjing Wei;
Yanrong Hao

Publication type:

Case Study

CDGSH Iron Sulfur Domain 2 Deficiency Inhibits Cell Proliferation and Induces Cell Differentiation of Neuroblastoma.

Published in:

Pathology & Oncology Research, 2020, v. 26, n. 3, p. 1725, doi. 10.1007/s12253-019-00753-7

By:

Li, Jia;
Duan, Haoyan;
Xuan, Fan;
Zhao, Erhu;
Huang, Mengying

Publication type:

Article

p38 Expression and Modulation of STAT3 Signaling in Oral Cancer.

Published in:

Pathology & Oncology Research, 2020, v. 26, n. 1, p. 183, doi. 10.1007/s12253-018-0405-9

By:

Gkouveris, I.;
Nikitakis, N.;
Sklavounou, A.

Publication type:

Article

Cyclins and cyclin-dependent kinases: from biology to tumorigenesis and therapeutic opportunities.

Published in:

Journal of Cancer Research & Clinical Oncology, 2023, v. 149, n. 4, p. 1585, doi. 10.1007/s00432-022-04135-6

By:

Zabihi, Mitra;
Lotfi, Ramin;
Yousefi, Amir-Mohammad;
Bashash, Davood

Publication type:

Article

"Hedgehog pathway": a potential target of itraconazole in the treatment of cancer.

Published in:

Journal of Cancer Research & Clinical Oncology, 2020, v. 146, n. 2, p. 297, doi. 10.1007/s00432-019-03117-5

By:

Wei, Xin;
Liu, Wu;
Wang, Jia Qi;
Tang, Zeyao

Publication type:

Article

MiR-26a and miR-138 block the G1/S transition by targeting the cell cycle regulating network in prostate cancer cells.

Published in:

Journal of Cancer Research & Clinical Oncology, 2016, v. 142, n. 11, p. 2249, doi. 10.1007/s00432-016-2222-4

By:

Erdmann, Kati;
Kaulke, Knut;
Rieger, Christiane;
Salomo, Karsten;
Wirth, Manfred;
Fuessel, Susanne

Publication type:

Article

Naringenin Induces ROS-Mediated ER Stress, Autophagy, and Apoptosis in Human Osteosarcoma Cell Lines.

Published in:

Molecules, 2022, v. 27, n. 2, p. 373, doi. 10.3390/molecules27020373

By:

Lee, Chiang-Wen;
Huang, Cathy Chia-Yu;
Chi, Miao-Ching;
Lee, Kuan-Han;
Peng, Kuo-Ti;
Fang, Mei-Ling;
Chiang, Yao-Chang;
Liu, Ju-Fang

Publication type:

Article

Cyclin-Dependent Kinase 4 and 6 Inhibitors in Cell Cycle Dysregulation for Breast Cancer Treatment.

Published in:

Molecules, 2021, v. 26, n. 15, p. 4462, doi. 10.3390/molecules26154462

By:

Susanti, Ni Made Pitri;
Tjahjono, Daryono Hadi

Publication type:

Article

Predicting Accurate Lead Structures for Screening Molecular Libraries: A Quantum Crystallographic Approach.

Published in:

Molecules, 2021, v. 26, n. 9, p. 2605, doi. 10.3390/molecules26092605

By:

Mandal, Suman Kumar;
Munshi, Parthapratim;
Gatti, Carlo;
Cooper, David L.;
Kohout, Miroslav;
Kuznetsov, Maxim L.

Publication type:

Article

Quo Vadis Advanced Prostate Cancer Therapy? Novel Treatment Perspectives and Possible Future Directions.

Published in:

Molecules, 2021, v. 26, n. 8, p. 2228, doi. 10.3390/molecules26082228

By:

Kvízová, Jana;
Pavlíčková, Vladimíra;
Kmoníčková, Eva;
Ruml, Tomáš;
Rimpelová, Silvie

Publication type:

Article

Activation of Hair Cell Growth Factors by Linoleic Acid in Malva verticillata Seed.

Published in:

Molecules, 2021, v. 26, n. 8, p. 2117, doi. 10.3390/molecules26082117

By:

Ryu, Hwa Sun;
Jeong, JiYeon;
Lee, Chun Mong;
Lee, Kwang Sik;
Lee, Jung-No;
Park, Sung-Min;
Lee, Yong-Moon

Publication type:

Article

A New CDK2 Inhibitor with 3-Hydrazonoindolin-2-One Scaffold Endowed with Anti-Breast Cancer Activity: Design, Synthesis, Biological Evaluation, and In Silico Insights.

Published in:

Molecules, 2021, v. 26, n. 2, p. 412, doi. 10.3390/molecules26020412

By:

Al-Sanea, Mohammad M.;
Obaidullah, Ahmad J.;
Shaker, Mohamed E.;
Chilingaryan, Garri;
Alanazi, Mohammed M.;
Alsaif, Nawaf A.;
Alkahtani, Hamad M.;
Alsubaie, Sultan A.;
Abdelgawad, Mohamed A.;
Marchand, Pascal

Publication type:

Article

Design, Synthesis, and Molecular Docking of Paracyclophanyl-Thiazole Hybrids as Novel CDK1 Inhibitors and Apoptosis Inducing Anti-Melanoma Agents.

Published in:

Molecules, 2020, v. 25, n. 23, p. 5569, doi. 10.3390/molecules25235569

By:

Aly, Ashraf A.;
Bräse, Stefan;
Hassan, Alaa A.;
Mohamed, Nasr K.;
El-Haleem, Lamiaa E. Abd;
Nieger, Martin;
Morsy, Nesrin M.;
Alshammari, Mohammed B.;
Ibrahim, Mahmoud A. A.;
Abdelhafez, Elshimaa M. N.

Publication type:

Article

Combination Antitumor Effect of Sorafenib via Calcium-Dependent Deactivation of Focal Adhesion Kinase Targeting Colorectal Cancer Cells.

Published in:

Molecules, 2020, v. 25, n. 22, p. 5299, doi. 10.3390/molecules25225299

By:

Jeong, Keun-Yeong;
Park, Minhee;
Sim, Jae-Jun;
Kim, Hwan Mook;
Pavelić, Krešimir;
Pavelic, Sandra Kraljevic

Publication type:

Article

Discovery of 12O—A Novel Oral Multi-Kinase Inhibitor for the Treatment of Solid Tumor.

Published in:

Molecules, 2020, v. 25, n. 21, p. 5199, doi. 10.3390/molecules25215199

By:

Fan, Yan;
Huang, Zhi;
Wang, Xiaoshuang;
Ma, Yakun;
Li, Yongtao;
Yang, Shengyong;
Shi, Yi

Publication type:

Article

Salinosporamide A, a Marine-Derived Proteasome Inhibitor, Inhibits T Cell Activation through Regulating Proliferation and the Cell Cycle.

Published in:

Molecules, 2020, v. 25, n. 21, p. 5031, doi. 10.3390/molecules25215031

By:

Lee, Hyun-Su;
Jeong, Gil-Saeng;
Sakai, Ryuichi

Publication type:

Article

16-Hydroxycleroda-3,13-Dien-15,16-Olide Induces Apoptosis in Human Bladder Cancer Cells through Cell Cycle Arrest, Mitochondria ROS Overproduction, and Inactivation of EGFR-Related Signalling Pathways.

Published in:

Molecules, 2020, v. 25, n. 17, p. 3958, doi. 10.3390/molecules25173958

By:

Chen, Yu-Chi;
Wang, Po-Yu;
Huang, Bu-Miin;
Chen, Yu-Jen;
Lee, Wei-Chang;
Chen, Yung-Chia;
Choi, Young Hee;
Chin, Young-won;
Kim, Hojun

Publication type:

Article

Costunolide Plays an Anti-Neuroinflammation Role in Lipopolysaccharide-Induced BV2 Microglial Activation by Targeting Cyclin-Dependent Kinase 2.

Published in:

Molecules, 2020, v. 25, n. 12, p. 2840, doi. 10.3390/molecules25122840

By:

Liu, Yan-Chen;
Feng, Na;
Li, Wei-Wei;
Tu, Peng-Fei;
Chen, Jian-Ping;
Han, Jing-Yan;
Zeng, Ke-Wu

Publication type:

Article

Synergistic Anti Leukemia Effect of a Novel Hsp90 and a Pan Cyclin Dependent Kinase Inhibitors.

Published in:

Molecules, 2020, v. 25, n. 9, p. 2220, doi. 10.3390/molecules25092220

By:

Abdalla, Ashraf N.;
Abdallah, Mohamed E.;
Aslam, Akhmed;
Bader, Ammar;
Vassallo, Antonio;
Tommasi, Nunziatina De;
Malki, Waleed H.;
Gouda, Ahmed M.;
Mukhtar, Mohammed H.;
El-Readi, Mahmoud Zaki;
Alkahtani, Hamad M.;
Abdel-Aziz, Alaa A.-M.;
El-Azab, Adel S.;
Tylkowski, Bartosz;
Bajek, Anna;
Roszkowski, Krzysztof

Publication type:

Article

Synthesis and Biological Evaluation of 2-Substituted Benzyl-/Phenylethylamino-4-amino-5-aroylthiazoles as Apoptosis-Inducing Anticancer Agents.

Published in:

Molecules, 2020, v. 25, n. 9, p. 2177, doi. 10.3390/molecules25092177

By:

Oliva, Paola;
Onnis, Valentina;
Balboni, Elisa;
Hamel, Ernest;
Estévez-Sarmiento, Francisco;
Quintana, José;
Estévez, Francisco;
Brancale, Andrea;
Ferla, Salvatore;
Manfredini, Stefano;
Romagnoli, Romeo;
Silvestri, Romano

Publication type:

Article

Synthesis, Biological Evaluation and In Silico Studies of Certain Oxindole–Indole Conjugates as Anticancer CDK Inhibitors.

Published in:

Molecules, 2020, v. 25, n. 9, p. 2031, doi. 10.3390/molecules25092031

By:

Al-Warhi, Tarfah;
El Kerdawy, Ahmed M.;
Aljaeed, Nada;
Ismael, Omnia E.;
Ayyad, Rezk R.;
Eldehna, Wagdy M.;
Abdel-Aziz, Hatem A.;
Al-Ansary, Ghada H.;
Gemma, Sandra

Publication type:

Article

Identification of High-Affinity Inhibitors of Cyclin-Dependent Kinase 2 Towards Anticancer Therapy.

Published in:

Molecules, 2019, v. 24, n. 24, p. 4589, doi. 10.3390/molecules24244589

By:

Mohammad, Taj;
Batra, Sagar;
Dahiya, Rashmi;
Baig, Mohammad Hassan;
Rather, Irfan Ahmad;
Dong, Jae-June;
Hassan, Imtaiyaz;
Tylkowski, Bartosz

Publication type:

Article

Anticancer Function and ROS-Mediated Multi-Targeting Anticancer Mechanisms of Copper (II) 2-hydroxy-1-naphthaldehyde Complexes.

Published in:

Molecules, 2019, v. 24, n. 14, p. 2544, doi. 10.3390/molecules24142544

By:

Khan, Muhammad Hamid;
Cai, Meiling;
Deng, Jungang;
Yu, Ping;
Liang, Hong;
Yang, Feng

Publication type:

Article

Modification of Boc-Protected CAN508 via Acylation and Suzuki-Miyaura Coupling.

Published in:

Molecules, 2018, v. 23, n. 1, p. 149, doi. 10.3390/molecules23010149

By:

Pisár, Martin;
Schütznerová, Eva;
Hančík, Filip;
Popa, Igor;
Trávníček, Zdeněk;
Cankař, Petr

Publication type:

Article

Drug Discovery of Host CLK1 Inhibitors for Influenza Treatment.

Published in:

Molecules, 2015, v. 20, n. 11, p. 19735, doi. 10.3390/molecules201119653

By:

Mian Zu;
Chao Li;
Jian-Song Fang;
Wen-Wen Lian;
Ai-Lin Liu;
Li-Shu Zheng;
Guan-Hua Du

Publication type:

Article

Therapeutic Targeting the Cell Division Cycle 25 (CDC25) Phosphatases in Human Acute Myeloid Leukemia — The Possibility to Target Several Kinases through Inhibition of the Various CDC25 Isoforms.

Published in:

Molecules, 2014, v. 19, n. 11, p. 18414, doi. 10.3390/molecules191118414

By:

Brenner, Annette K.;
Reikvam, Håkon;
Lavecchia, Antonio;
Bruserud, Øystein

Publication type:

Article

Investigation of the Flexibility of Protein Kinases Implicated in the Pathology of Alzheimer's Disease.

Published in:

Molecules, 2014, v. 19, n. 7, p. 9134, doi. 10.3390/molecules19079134

By:

Mazanetz, Michael P.;
Laughton, Charles A.;
Fischer, Peter M.

Publication type:

Article

Synergism of Cyclin-Dependent Kinase Inhibitors with Camptothecin Derivatives in Small Cell Lung Cancer Cell Lines.

Published in:

Molecules, 2014, v. 19, n. 2, p. 2077, doi. 10.3390/molecules19022077

By:

Hamilton, Gerhard;
Klameth, Lukas;
Rath, Barbara;
Thalhammer, Theresia

Publication type:

Article

Effects of the Cyclin-Dependent Kinase 10 (CDK10) on the Tamoxifen Sensitivity of Keloid Samples.

Published in:

Molecules, 2012, v. 17, n. 2, p. 1307, doi. 10.3390/molecules17021307

By:

Ying Liu;
Zhibo Xiao;
Daping Yang;
Lihong Ren;
Guofeng Liu;
Lin Yang

Publication type:

Article

A Facile One-pot Synthesis of 1-Arylpyrazolo[3,4-d]Pyrimidin-4-ones.

Published in:

Molecules, 2010, v. 15, n. 5, p. 3079, doi. 10.3390/molecules15053079

By:

Xiaohong Zhang;
Qiulian Lin;
Ping Zhong

Publication type:

Article