Works matching DE "CYCLIN-dependent kinase inhibitors"

Results: 1242
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    ESR1 testing on FFPE samples from metastatic lesions in HR + /HER2- breast cancer after progression on CDK4/6 inhibitor therapy.

    Published in:
    Breast Cancer Research, 2025, v. 27, n. 1, p. 1, doi. 10.1186/s13058-025-02020-x
    By:
    • Venetis, Konstantinos;
    • Cursano, Giulia;
    • Scafetta, Roberta;
    • Giachetti, Pier Paolo Maria Berton;
    • Concardi, Alberto;
    • De Camilli, Elisa;
    • D'Ercole, Marianna;
    • Mane, Eltjona;
    • Frascarelli, Chiara;
    • Marra, Antonio;
    • Gandini, Sara;
    • Pepe, Francesco;
    • Scagnoli, Simone;
    • Rossi, Silvia Maria;
    • Troiano, Raffaella;
    • Speziale, Elena;
    • De Angelis, Carmine;
    • Troncone, Giancarlo;
    • Malapelle, Umberto;
    • Perrone, Giuseppe
    Publication type:
    Article
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    Basal-shift transformation leads to EGFR therapy-resistance in human lung adenocarcinoma.

    Published in:
    Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-59623-3
    By:
    • Shinozaki, Taro;
    • Togasaki, Kazuhiro;
    • Hamamoto, Junko;
    • Mitsuishi, Akifumi;
    • Fukushima, Takahiro;
    • Sugihara, Kai;
    • Ebisudani, Toshiki;
    • Okada, Masahiko;
    • Saito, Ayaka;
    • Shigematsu, Lisa;
    • Takaoka, Hatsuyo;
    • Ito, Fumimaro;
    • Ohgino, Keiko;
    • Ishioka, Kota;
    • Watanabe, Kageaki;
    • Hishima, Tsunekazu;
    • Kurebayashi, Yutaka;
    • Emoto, Katsura;
    • Terai, Hideki;
    • Ikemura, Shinnosuke
    Publication type:
    Article
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    Combination therapy of adagrasib and abemaciclib in non-small cell lung cancer brain metastasis models genomically characterized by KRAS-G12C and homozygous loss of CDKN2A.

    Published in:
    Acta Neuropathologica Communications, 2025, v. 13, n. 1, p. 1, doi. 10.1186/s40478-025-01993-2
    By:
    • Migliarese, Christian;
    • Sadeh, Yinon;
    • Torrini, Consuelo;
    • Turna Demir, Fatma;
    • Nayyar, Naema;
    • Yamazawa, Erika;
    • Ishikawa, Yuu;
    • Ijad, Nazanin;
    • Summers, Elizabeth J.;
    • Elliott, Adam;
    • Rahbaek, Lisa;
    • Saechao, Barbara;
    • Hallin, Jill;
    • Brastianos, Priscilla K.;
    • Wakimoto, Hiroaki
    Publication type:
    Article
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    Comparative biomarker analysis of PALOMA-2/3 trials for palbociclib.

    Published in:
    NPJ Precision Oncology, 2022, v. 6, n. 1, p. 1, doi. 10.1038/s41698-022-00297-1
    By:
    • Zhu, Zhou;
    • Turner, Nicholas C.;
    • Loi, Sherene;
    • André, Fabrice;
    • Martin, Miguel;
    • Diéras, Véronique;
    • Gelmon, Karen A.;
    • Harbeck, Nadia;
    • Zhang, Cathy;
    • Cao, Joan Q.;
    • Yan, Zhengming;
    • Lu, Dongrui R.;
    • Wei, Ping;
    • VanArsdale, Todd L.;
    • Rejto, Paul A.;
    • Huang, Xin;
    • Rugo, Hope S.;
    • Loibl, Sibylle;
    • Cristofanilli, Massimo;
    • Finn, Richard S.
    Publication type:
    Article
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    Discovery and characterization of a specific inhibitor of serine-threonine kinase cyclin-dependent kinase-like 5 (CDKL5) demonstrates role in hippocampal CA1 physiology.

    Published in:
    eLife, 2023, p. 1, doi. 10.7554/eLife.88206
    By:
    • Castano, Anna;
    • Silvestre, Margaux;
    • Wells, Carrow I.;
    • Sanderson, Jennifer L.;
    • Ferrer, Carla A.;
    • Han Wee Ong;
    • Yi Lang;
    • Richardson, William;
    • Silvaroli, Josie A.;
    • Bashore, Frances M.;
    • Smith, Jeffery L.;
    • Genereux, Isabelle M.;
    • Dempster, Kelvin;
    • Drewry, David H.;
    • Pabla, Navlot S.;
    • Bullock, Alex N.;
    • Benke, Tim A.;
    • Ultanir, Sila K.;
    • Axtman, Alison D.
    Publication type:
    Article
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