Works matching DE "CYCLIC guanylic acid"

Results: 1062

Chloroquine induces endothelium-dependent nitric oxide-mediated vasodilation in isolated rat aorta.

Published in:

General Physiology & Biophysics, 2025, v. 44, n. 3, p. 201, doi. 10.4149/gpb_2025006

By:

Soo Hee Lee;
Kyeong-Eon Park;
Yeran Hwang;
Sung Il Bae;
Seong-Ho Ok;
Seung Hyun Ahn;
Gyujin Sim;
Seunghyeon Park;
Ju-Tae Sohn

Publication type:

Article

Spectrofluorimetric determination of cyclic guanosine monophosphate in human nasal secretions: evaluating levels in healthy individuals and patients with olfactory dysfunction.

Published in:

BMC Chemistry, 2025, v. 19, n. 1, p. 1, doi. 10.1186/s13065-025-01530-1

By:

Abdelazim, Mohamed H.;
Alsenani, Faisal;
Alharbi, Adnan;
Baali, Fahad H.;
Baali, Abdulaziz H.;
Abduljabbar, Maram H.;
Alnemari, Reem M.;
Algarni, Majed A.

Publication type:

Article

海洋暖化对细菌生物被膜及其诱导厚壳贻贝幼虫变态能力的影响.

Published in:

Journal of Dalian Ocean University, 2025, v. 40, n. 2, p. 241, doi. 10.16535/j.cnki.dlhyxb.2024-205

By:

马蕃;
陶钰;
杨金龙;
梁箫

Publication type:

Article

Inhibition of phosphodiesterases 1 and 4 prevents myofibroblast transformation in Peyronie's disease.

Published in:

BJU International, 2025, v. 135, n. 5, p. 810, doi. 10.1111/bju.16631

By:

Harding, Sophie L.;
Ilg, Marcus M.;
Bustin, Stephen A.;
Ralph, David J.;
Cellek, Selim

Publication type:

Article

cGAS‐STING Pathway's Impact on Intestinal Barrier.

Published in:

Journal of Gastroenterology & Hepatology, 2025, v. 40, n. 6, p. 1381, doi. 10.1111/jgh.16974

By:

Li, Liqi;
He, Yingge;
Chen, Yu;
Zhou, Xiaoshu

Publication type:

Article

Methotrexate exerts antitumor immune activity and improves the clinical efficacy of immunotherapy in patients with solid tumors.

Published in:

Science Translational Medicine, 2025, v. 17, n. 801, p. 1, doi. 10.1126/scitranslmed.adn6921

By:

Yang, Ruirui;
Wang, Bei;
Su, Zhaoming;
Song, Ying;
Zhang, Yingying;
Liu, Yadan;
Zhang, Yinghui;
He, Changyu;
Yang, Xi;
Zhong, Feisheng;
Fu, Zunyun;
Ding, Yiluan;
Zhang, Naixia;
Li, Rui;
Chu, Shuqing;
Xu, Chuanhai;
Sun, Jian;
Shen, Haiwei;
Geng, Wei;
Zhang, Sulin

Publication type:

Article

Nociceptor-specific signaling of the receptor guanylyl cyclase Npr2 contributes to acute and persistent pain.

Published in:

Science Signaling, 2025, v. 18, n. 889, p. 1, doi. 10.1126/scisignal.adq4238

By:

Gerninghaus, Hannah;
Isensee, Jörg;
Kennel, Lea;
Zhou, Fangyuan;
Kaiser, Anja;
Gross, Tilman;
Flauaus, Cathrin;
Engel, Patrick;
Jacobs, Christoph;
Petersen, Jonas;
Kallenborn-Gerhardt, Wiebke;
Lu, Ruirui;
Metzner, Katharina;
Adler, Julia;
Ruth, Peter;
Lukowski, Robert;
Hucho, Tim;
Schmidt, Hannes;
Schmidtko, Achim

Publication type:

Article

Membrane-Mediated Action of Phosphodiesterase 5 Inhibitors.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 563, doi. 10.3390/pharmaceutics17050563

By:

Malykhina, Anna I.;
Efimova, Svetlana S.;
Ostroumova, Olga S.

Publication type:

Article

Influence of Soluble Guanylate Cyclase on Cardiac, Vascular, and Renal Structure and Function: A Physiopathological Insight.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4550, doi. 10.3390/ijms26104550

By:

De Feo, Daniele;
Massari, Francesco;
Campanella, Cosimo;
Livrieri, Anna;
Ciccone, Marco Matteo;
Caldarola, Pasquale;
De Palo, Micaela;
Scicchitano, Pietro

Publication type:

Article

The structural basis for the sensing and binding of cyclic di-GMP by STING.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 7, p. 728, doi. 10.1038/nsmb.2333

By:

Huang, Yi-He;
Liu, Xiang-Yu;
Du, Xiao-Xia;
Jiang, Zheng-Fan;
Su, Xiao-Dong

Publication type:

Article

Structure of STING bound to cyclic di-GMP reveals the mechanism of cyclic dinucleotide recognition by the immune system.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 7, p. 722, doi. 10.1038/nsmb.2331

By:

Shu, Chang;
Yi, Guanghui;
Watts, Tylan;
Kao, C Cheng;
Li, Pingwei

Publication type:

Article

Crystal structures of STING protein reveal basis for recognition of cyclic di-GMP.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 7, p. 725, doi. 10.1038/nsmb.2332

By:

Shang, Guijun;
Zhu, Deyu;
Li, Ning;
Zhang, Junbing;
Zhu, Chunyuan;
Lu, Defen;
Liu, Cuilan;
Yu, Qian;
Zhao, Yanyu;
Xu, Sujuan;
Gu, Lichuan

Publication type:

Article

Structural basis of ligand binding by a c-di-GMP riboswitch.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 12, p. 1218, doi. 10.1038/nsmb.1702

By:

Smith, Kathryn D.;
Lipchock, Sarah V.;
Ames, Tyler D.;
Jimin Wang;
Breaker, Ronald R.;
Strobel, Scott A.

Publication type:

Article

Principles of c-di-GMP signalling in bacteria.

Published in:

Nature Reviews Microbiology, 2009, v. 7, n. 4, p. 263, doi. 10.1038/nrmicro2109

By:

Hengge, Regine

Publication type:

Article

Bacterial genetics: A hidden GEMM.

Published in:

Nature Reviews Microbiology, 2008, v. 6, n. 9, p. 649, doi. 10.1038/nrmicro1976

By:

Smallridge, Rachel

Publication type:

Article

Cyclic Guanidine Compounds from Toxic Newts Support the Hypothesis that Tetrodotoxin is Derived from a Monoterpene.

Published in:

Angewandte Chemie, 2016, v. 128, n. 30, p. 8870, doi. 10.1002/ange.201602971

By:

Kudo, Yuta;
Yasumoto, Takeshi;
Mebs, Dietrich;
Cho, Yuko;
Konoki, Keiichi;
Yotsu ‐ Yamashita, Mari

Publication type:

Article

Targeting phosphodiesterase 4 as a potential therapy for Parkinson's disease: a review.

Published in:

Molecular Biology Reports, 2024, v. 51, n. 1, p. 1, doi. 10.1007/s11033-024-09484-8

By:

Nongthombam, Pooja Devi;
Haobam, Reena

Publication type:

Article

Urinary 8-hydroxydeoxyguanosine is elevated in patients with nephrolithiasis.

Published in:

Urological Research, 2007, v. 35, n. 4, p. 185, doi. 10.1007/s00240-007-0098-0

By:

Boonla, Chanchai;
Wunsuwan, Rattiporn;
Tungsanga, Kriang;
Tosukhowong, Piyaratana

Publication type:

Article

Electrochemical behaviors of GMP based on solid-phase extractionon at Cu-Mg-Al hydrotalcite-like compound (HTLC) modified glass carbon electrode.

Published in:

Journal of Solid State Electrochemistry, 2011, v. 15, n. 6, p. 1253, doi. 10.1007/s10008-010-1185-7

By:

Lin Cui;
Lifang Li;
Shiyun Ai;
Huanshun Yin;
Peng Ju;
Tao Liu

Publication type:

Article

Protection through postconditioning or a mitochondria-targeted S-nitrosothiol is unaffected by cardiomyocyte-selective ablation of protein kinase G.

Published in:

Basic Research in Cardiology, 2013, v. 108, n. 2, p. 1, doi. 10.1007/s00395-013-0337-1

By:

Methner, Carmen;
Lukowski, Robert;
Grube, Karina;
Loga, Florian;
Smith, Robin;
Murphy, Michael;
Hofmann, Franz;
Krieg, Thomas

Publication type:

Article

GGDEF proteins YeaI, YedQ, and YfiN reduce early biofilm formation and swimming motility in Escherichia coli.

Published in:

Applied Microbiology & Biotechnology, 2011, v. 90, n. 2, p. 651, doi. 10.1007/s00253-010-3074-5

By:

Sanchez-Torres, Viviana;
Hongbo Hu;
Wood, Thomas K.

Publication type:

Article

Transcriptome analysis reveals the main metabolic pathway of c-GMP induced by salt stress in tomato (Solanum lycopersicum) seedlings<sup>†</sup>.

Published in:

Functional Plant Biology, 2022, v. 49, n. 9, p. 784, doi. 10.1071/FP21337

By:

Zhu, Xiaolin;
Su, Meifei;
Wang, Baoqiang;
Wei, Xiaohong

Publication type:

Article

The predatory soil bacterium Lysobacter reprograms quorum sensing system to regulate antifungal antibiotic production in a cyclic-di-GMP-independent manner.

Published in:

Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02660-7

By:

Li, Kaihuai;
Xu, Gaoge;
Wang, Bo;
Wu, Guichun;
Hou, Rongxian;
Liu, Fengquan

Publication type:

Article

Anti-thrombotic effects of arteanoflavone by regulating cyclic nucleotides and aggregation on human platelets.

Published in:

Applied Biological Chemistry, 2024, v. 67, n. 1, p. 1, doi. 10.1186/s13765-024-00914-6

By:

Choi, Ho Keun;
Kim, Ga Yeon;
Lee, Ga Hee;
su Jang, Hee;
Kang, Da Hyeon;
Lee, Jin Pyo;
Lee, Dong-Ha

Publication type:

Article

Marla Sokolowski Retrospectively.

Published in:

Journal of Neurogenetics, 2021, v. 35, n. 3, p. 107, doi. 10.1080/01677063.2021.1940169

By:

Atwood, Harold L.

Publication type:

Article

Neurotoxicity of cGMP in the vertebrate retina: from the initial research on rd mutant mice to zebrafish genetic approaches.

Published in:

Journal of Neurogenetics, 2017, v. 31, n. 3, p. 88, doi. 10.1080/01677063.2017.1358268

By:

Iribarne, Maria;
Masai, Ichiro

Publication type:

Article

The importance of the nitric oxide‐cGMP pathway in age‐related cardiovascular disease: Focus on phosphodiesterase‐1 and soluble guanylate cyclase.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2020, v. 127, n. 2, p. 67, doi. 10.1111/bcpt.13319

By:

Golshiri, Keivan;
Ataei Ataabadi, Ehsan;
Portilla Fernandez, Eliana C.;
Jan Danser, A. H.;
Roks, Anton J. M.

Publication type:

Article

Mechanisms of Actions Involved in The Antinociceptive Effect of Estragole and its β -Cyclodextrin Inclusion Complex in Animal Models.

Published in:

Plants (2223-7747), 2022, v. 11, n. 21, p. 2854, doi. 10.3390/plants11212854

By:

da Costa, Roger Henrique Sousa;
Martins, Anita Oliveira Brito Pereira Bezerra;
Pessoa, Renata Torres;
Alshehri, Saad Ali;
Wahab, Shadma;
Ahmad, Md Faruque;
Suliman, Muath;
da Silva, Lucas Yure Santos;
Alcântara, Isabel Sousa;
Ramos, Andreza Guedes Barbosa;
Oliveira, Maria Rayane Correia de;
Batista, Francisco Lucas Alves;
Delmondes, Gyllyandeson de Araújo;
de Farias, Pablo Antonio Maia;
Rocha, Janaína Esmeraldo;
Coutinho, Henrique Douglas Melo;
Raposo, António;
Carrascosa, Conrado;
Jaber, José Raduan;
de Menezes, Irwin Rose Alencar

Publication type:

Article

Nitrated Cyclic GMP Modulates Guard Cell Signaling in Arabidopsis.

Published in:

Plant Cell, 2013, v. 25, n. 2, p. 558, doi. 10.1105/tpc.112.105049

By:

Joudoi, Takahiro;
Shichiri, Yudai;
Kamizono, Nobuto;
Akaike, Takaaki;
Sawa, Tomohiro;
Yoshitake, Jun;
Yamada, Naotaka;
Iwai, Sumio

Publication type:

Article

Activation of the cGMP/Protein Kinase G Pathway by Nitric Oxide Can Decrease TRPV1 Activity in Cultured Rat Dorsal Root Ganglion Neurons.

Published in:

Korean Journal of Physiology & Pharmacology, 2012, v. 16, n. 3, p. 211, doi. 10.4196/kjpp.2012.16.3.211

By:

Yunju Jin;
Jun Kim;
Jiyeon Kwak

Publication type:

Article

Differential regulation of the nitric oxide–cGMP pathway exacerbates postischaemic heart injury in stroke-prone hypertensive rats.

Published in:

Experimental Physiology, 2007, v. 92, n. 1, p. 147, doi. 10.1113/expphysiol.2006.035097

By:

Itoh, Tetsuji;
Haruna, Masao;
Abe, Kohji

Publication type:

Article

Relationships between nitric oxide-mediated endothelial function, eNOS coupling and blood pressure revealed by eNOS–GTP cyclohydrolase 1 double transgenic mice.

Published in:

Experimental Physiology, 2007, v. 92, n. 1, p. 119, doi. 10.1113/expphysiol.2006.035113

By:

Adlam, D.;
Bendall, J. K.;
De Bono, J. P.;
Alp, N. J.;
Khoo, J.;
Nicoli, T.;
Yokoyama, M.;
Kawashima, S.;
Channon, K. M.

Publication type:

Article

Beating the silent killer: a new way to relax.

Published in:

Biologist, 2009, v. 56, n. 1, p. 40

By:

Burgoyne, Joseph R.;
Eaton, Philip

Publication type:

Article

Identifying Phosphodiesterase‐5 Inhibitors with Drug Repurposing Approach: Implications in Vasodysfunctional Disorders.

Published in:

ChemistryOpen, 2024, v. 13, n. 5, p. 1, doi. 10.1002/open.202300196

By:

Khan, Mohd Shahnawaz;
Mohammad, Hamza Ahmad;
Shahwan, Moyad;
Yadav, Dharmendra Kumar;
Anwar, Saleha;
Shamsi, Anas

Publication type:

Article

Inhibition of multidrug resistance proteins by MK571 restored the erectile function in obese mice through cGMP accumulation.

Published in:

Andrology, 2023, v. 11, n. 3, p. 611, doi. 10.1111/andr.13340

By:

de Oliveira, Mariana Gonçalves;
Passos, Gabriela Reolon;
de Gomes, Erick de Toledo;
Leonardi, Guilherme Ruiz;
Zapparoli, Adriana;
Antunes, Edson;
Mónica, Fabiola Zakia

Publication type:

Article

Prolonged isoflurane anesthesia‐induced acidosis decreases penile intracavernous pressure in rats.

Published in:

Andrology, 2022, v. 10, n. 1, p. 143, doi. 10.1111/andr.13085

By:

Yu, Botao;
Qin, Feng;
Wei, Shanzun;
Wu, Changjing;
Ma, Ming;
Yuan, Jiuhong

Publication type:

Article

JAK2 deficiency improves erectile function in diabetic mice through attenuation of oxidative stress, apoptosis, and fibrosis.

Published in:

Andrology, 2021, v. 9, n. 5, p. 1662, doi. 10.1111/andr.13061

By:

Li, Hao;
Xu, Wenchao;
Liu, Xiaming;
Wang, Tao;
Wang, Shaogang;
Liu, Jihong;
Jiang, Hongyang

Publication type:

Article

Testosterone positively regulates functional responses and nitric oxide expression in the isolated human corpus cavernosum.

Published in:

Andrology, 2020, v. 8, n. 6, p. 1824, doi. 10.1111/andr.12866

By:

Gur, Serap;
Alzweri, Laith;
Yilmaz‐Oral, Didem;
Kaya‐Sezginer, Ecem;
Abdel‐Mageed, Asim B;
Dick, Brian;
Sikka, Suresh C.;
Volkan Oztekin, Cetin;
Hellstrom, Wayne J. G.

Publication type:

Article

Study of the Differentially Expressed Genes in the Pomacea canaliculata Transcriptome after Treatment with Pedunsaponin A.

Published in:

Metabolites (2218-1989), 2019, v. 9, n. 11, p. 268, doi. 10.3390/metabo9110268

By:

Yang, Chunping;
Lv, Tianxing;
Zhang, Yangyang;
Wang, Bin;
Zhao, Xiaomin;
Zhang, Min;
Gong, Guoshu;
Chang, Xiaoli;
Yue, Guizhou;
Qiu, Xiaoyan;
Luo, Liya;
Chen, Huabao

Publication type:

Article

Damage Signaling by Extracellular Nucleotides: A Role for Cyclic Nucleotides in Elevating Cytosolic Free Calcium?

Published in:

Frontiers in Plant Science, 2021, v. 12, p. 1, doi. 10.3389/fpls.2021.788514

By:

Sun, Jian;
Ning, Youzheng;
Wang, Limin;
Wilkins, Katie A.;
Davies, Julia M.

Publication type:

Article

PDE3 Inhibition Reduces Epithelial Mast Cell Numbers in Allergic Airway Inflammation and Attenuates Degranulation of Basophils and Mast Cells.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. 1, doi. 10.3389/fphar.2020.00470

By:

Beute, Jan;
Ganesh, Keerthana;
Nastiti, Hedwika;
Hoogenboom, Robin;
Bos, Vivica;
Folkerts, Jelle;
Schreurs, Marco W. J.;
Hockman, Steve;
Hendriks, Rudi W.;
KleinJan, Alex

Publication type:

Article

Time Course of the Effects of Buxin Yishen Decoction in Promoting Heart Function and Inhibiting the Progression of Renal Fibrosis in Myocardial Infarction Caused Type 2 Cardiorenal Syndrome Rats.

Published in:

Frontiers in Pharmacology, 2019, v. 10, p. 1, doi. 10.3389/fphar.2019.01267

By:

Qiu, Qi;
Cao, Jinglin;
Wang, Yong;
Zhang, Yunnan;
Wei, Yun;
Hao, Xiaoyan;
Mu, Yu;
Lin, Yang

Publication type:

Article

YciR, a Specific 30-Phosphodiesterase, Plays a Role in the Pathogenesis of Uropathogenic Escherichia coli CFT073.

Published in:

Frontiers in Microbiology, 2022, v. 13, p. 1, doi. 10.3389/fmicb.2022.910906

By:

Si Zhang;
Jingting Wang;
Yu Fan;
Wang Meng;
Chengqian Qian;
Peng Liu;
Yi Wei;
Chao Yuan;
Yuhui Du;
Zhiqiu Yin

Publication type:

Article

Putative Nucleotide-Based Second Messengers in the Archaeal Model Organisms Haloferax volcanii and Sulfolobus acidocaldarius.

Published in:

Frontiers in Microbiology, 2021, v. 12, p. 1, doi. 10.3389/fmicb.2021.779012

By:

Braun, Frank;
Recalde, Alejandra;
Bähre, Heike;
Seifert, Roland;
Albers, Sonja-Verena

Publication type:

Article

A Receptor Guanylate Cyclase, Gyc76C, Mediates Humoral, and Cellular Responses in Distinct Ways in Drosophila Immunity.

Published in:

Frontiers in Immunology, 2020, p. 1, doi. 10.3389/fimmu.2020.00035

By:

Iwashita, Shinzo;
Suzuki, Hiroaki;
Goto, Akira;
Oyama, Tomohito;
Kanoh, Hirotaka;
Kuraishi, Takayuki;
Fuse, Naoyuki;
Yano, Tamaki;
Oshima, Yoshiteru;
Dow, Julian A. T.;
Davies, Shireen-Anne;
Kurata, Shoichiro

Publication type:

Article

Root hair quantification is an accessible approach to phenotyping important functional traits.

Published in:

Journal of Experimental Botany, 2022, v. 73, n. 11, p. 3304, doi. 10.1093/jxb/erac102

By:

Vincent, Christopher;
Ebert, Rebecca;
Hermans, Christian

Publication type:

Article

The evolution of nitric oxide signalling diverges between animal and green lineages.

Published in:

Journal of Experimental Botany, 2019, v. 70, n. 17, p. 4355, doi. 10.1093/jxb/erz088

By:

Astier, Jeremy;
Mounier, Arnaud;
Santolini, Jérôme;
Jeandroz, Sylvain;
Wendehenne, David

Publication type:

Article

Sodium in plants: perception, signalling, and regulation of sodium fluxes.

Published in:

Journal of Experimental Botany, 2014, v. 65, n. 3, p. 849, doi. 10.1093/jxb/ert326

By:

Maathuis, Frans J. M.

Publication type:

Article

Promotion of nitric oxide production: mechanisms, strategies, and possibilities.

Published in:

2025

By:

Gonzalez, Marcos;
Clayton, Sarah;
Wauson, Eric;
Christian, Daniel;
Tran, Quang-Kim

Publication type:

Literature Review

The cGMP Pathway and Inherited Photoreceptor Degeneration: Targets, Compounds, and Biomarkers.

Published in:

Genes, 2019, v. 10, n. 6, p. 453, doi. 10.3390/genes10060453

By:

Tolone, Arianna;
Belhadj, Soumaya;
Rentsch, Andreas;
Schwede, Frank;
Paquet-Durand, François

Publication type:

Article