Works about CROCIN

Results: 405

Crocin Mitigates Age Related Sarcopenia in Rats By Increased Mitochondrial Activity and Up-Regulation of Nrf2/HO-1 Pathway.

Published in:

Egyptian Journal of Hospital Medicine, 2025, v. 99, n. 1, p. 1431, doi. 10.21608/ejhm.2025.421222

By:

Shaban, Anwaar M.;
Amer, Mohamed Shebl;
El-Aziz, Noha M. Abd;
Moussa, Salwa Galal;
Khader, Heba F.;
Khodir, Suzan A.

Publication type:

Article

Myocardial infarction model in rats: can crocin reverse myocardial infarction-induced cardiac hepatopathy in melatonin deficiency?

Published in:

Biotechnic & Histochemistry, 2025, v. 100, n. 5, p. 270, doi. 10.1080/10520295.2025.2510214

By:

Yigitturk, Gurkan;
Elbe, Hulya;
Cetinavci, Dilan;
Turkis, Fulden Cantas;
Bicer, Yasemin;
Karayakali, Melike;
Altinoz, Eyup

Publication type:

Article

Rapid isolation and characterization of crocins, picrocrocin, and crocetin from saffron using centrifugal partition chromatography and LC–MS.

Published in:

Journal of Separation Science, 2018, v. 41, n. 22, p. 4105, doi. 10.1002/jssc.201800516

By:

Karkoula, Evangelia;
Angelis, Apostolis;
Koulakiotis, Nikolaos‐Stavros;
Gikas, Evangelos;
Halabalaki, Maria;
Tsarbopoulos, Anthony;
Skaltsounis, Alexios‐Leandros

Publication type:

Article

Enhancing Male Fertility: The Role of Crocin in Boosting Sperm Motility Through Antioxidant Activity and Mitochondrial Pathways.

Published in:

Journal of Biochemical & Molecular Toxicology, 2025, v. 39, n. 5, p. 1, doi. 10.1002/jbt.70275

By:

Boussabbeh, Manel;
Haddar, Manel;
Sallem, Amira;
Chaieb, Abir;
Khdhiri, Rania;
Abid‐Essefi, Salwa;
Mehdi, Meriem

Publication type:

Article

Crocin treatment promotes the oxidative stress and apoptosis in human thyroid cancer cells FTC‐133 through the inhibition of STAT/JAK signaling pathway.

Published in:

Journal of Biochemical & Molecular Toxicology, 2021, v. 35, n. 1, p. 1, doi. 10.1002/jbt.22608

By:

Zhang, Yonggang;
Zhu, Meng;
Krishna Mohan, Surapaneni;
Hao, Zhi

Publication type:

Article

Optimization of a Solid-Phase Extraction Procedure for the Separation of Picrocrocin and Crocins from Saffron Extract.

Published in:

Compounds, 2023, v. 3, n. 1, p. 233, doi. 10.3390/compounds3010019

By:

Revelou, Panagiota-Kyriaki;
Kougianou, Eleni;
Xagoraris, Marinos;
Evangelaras, Haralambos;
Papadopoulos, George K.;
Kanakis, Charalabos D.;
Strati, Irini F.;
Pappas, Christos S.;
Tarantilis, Petros A.

Publication type:

Article

Crocin suppressed cold allodynia and anxiety through α2- adrenoceptors in the anterior cingulate cortex following chronic constriction injury of sciatic nerve in rats.

Published in:

Journal of Research in Pharmacy, 2020, v. 24, n. 6, p. 833, doi. 10.35333/jrp.2020.242

By:

ZOHREHVAND, Mohammad Reza;
KAZEMI, Reza;
MIRASHEH, Mohammad Hassan;
BAHRAMI, Farideh;
ZABIHIAN, Mohammad Ali;
MEFTAHI, Gholam Hossein;
RAHIMI-Nasrabadi, Mehdi;
BAHARI, Zahra

Publication type:

Article

Unveiling the Intimate Mechanism of the Crocin Antioxidant Properties by Radiolytic Analysis and Molecular Simulations.

Published in:

Antioxidants, 2023, v. 12, n. 6, p. 1202, doi. 10.3390/antiox12061202

By:

Gharib, Sarah Al;
Archirel, Pierre;
Adjei, Daniel;
Belloni, Jacqueline;
Mostafavi, Mehran

Publication type:

Article

On the Importance of the Starting Material Choice and Analytical Procedures Adopted When Developing a Strategy for the Nanoencapsulation of Saffron (Crocus sativus L.) Bioactive Antioxidants.

Published in:

Antioxidants, 2023, v. 12, n. 2, p. 496, doi. 10.3390/antiox12020496

By:

Tsimidou, Maria Z.

Publication type:

Article

Accelerating synergistic effects of preconditioned mesenchymal stem cells with Crocin and dexamethasone in pulmonary epithelial cells injury.

Published in:

Toxicology Research, 2023, v. 12, n. 3, p. 369, doi. 10.1093/toxres/tfad016

By:

Jamshidi, Vahid;
Halabian, Raheleh;
Saeedi, Pardis;
Bagheri, Hasan;
Nobakht Motlagh Ghoochani, Bibi Fatemeh

Publication type:

Article

Crocin averts functional and structural rat hepatic disturbances induced by copper oxide nanoparticles.

Published in:

Toxicology Research, 2022, v. 11, n. 6, p. 911, doi. 10.1093/toxres/tfac064

By:

Yousef, Doaa Mohammed;
Hassan, Heba Ahmed;
Nafea, Ola Elsayed;
El Fattah, Eman Ramadan Abd

Publication type:

Article

Crocin attenuates oxidative and inflammatory stress-related periodontitis in cardiac tissues in rats.

Published in:

Advances in Clinical & Experimental Medicine, 2021, v. 30, n. 5, p. 517, doi. 10.17219/acem/133753

By:

Kocaman, Gulhan;
Altinoz, Eyup;
Erdemli, Mehmet Erman;
Gul, Mehmet;
Erdemli, Zeynep;
Zayman, Emrah;
Gozukara Bag, Harika Gozde;
Aydın, Tugba

Publication type:

Article

Effects of crocin on SUMOylation patterns in intoxication with diazinon in heart of rats.

Published in:

Medical journal of Mashhad University of Medical Sciences, 2016, v. 59, p. 41

By:

Pourtaji, Atena;
Abnous, Khalil;
Ramezani, Mohammad;
Hoseinzadeh, Hosein;
Razavi, Bibi Marjan

Publication type:

Article

Structural characterization of highly glucosylated crocins and regulation of their biosynthesis during flower development in Crocus.

Published in:

Frontiers in Plant Science, 2015, p. 1, doi. 10.3389/fpls.2015.00971

By:

Ahrazem, Oussama;
Rubio-Moraga, Angela;
Jimeno, Maria L.;
Gómez-Gómez, Lourdes

Publication type:

Article

Crocin promotes ferroptosis in gastric cancer via the Nrf2/GGTLC2 pathway.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1527481

By:

Yan, Nan;
Li, Gaofu;
Zhao, Linglin;
Guo, Qijing;
Yang, Jie;
Liu, Jianhong;
Zhou, Wei;
Gao, Yue;
Luo, Yushuang

Publication type:

Article

Reversal of anxiety-like depression induced by chronic corticosterone by crocin I and surface-enhanced Raman spectroscopy monitoring of plasma metabolites.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1540551

By:

Zhang, Dandan;
Wu, Zhuodi;
Yang, Doudou;
Zhao, Guanjie;
Zhang, Yanru;
Mou, Weifeng;
Liang, Yinku

Publication type:

Article

Role of Cannabinoid Receptors in Crocin-Induced Hypoalgesia in Neuropathic Pain in Rats.

Published in:

Journal of Experimental Pharmacology, 2020, v. 12, p. 97, doi. 10.2147/JEP.S250738

By:

Vafaei, Abbas Ali;
Safakhah, Hossein Ali;
Jafari, Simin;
Tavasoli, Azin;
Rashidy-Pour, Ali;
Ghanbari, Ali;
Seyedinia, Seyed Ali;
Tarahomi, Parnia

Publication type:

Article

[Retracted] Crocin protects against dexamethasone?induced osteoblast apoptosis by inhibiting the ROS/Ca2+?mediated mitochondrial pathway.

Published in:

2025

By:

Nie, Zhigang;
Deng, Shuang;
Zhang, Lei;
Chen, Sen;
Lu, Qiang;
Peng, Hao

Publication type:

Correction Notice

Crocin inhibits KBTBD7 to prevent excessive inflammation and cardiac dysfunction following myocardial infarction.

Published in:

Molecular Medicine Reports, 2023, v. 27, n. 1, p. N.PAG

By:

Yuan, Chunju;
Chen, Zhongpu;
Zhou, Qianxing

Publication type:

Article

Crocin protects against dexamethasone-induced osteoblast apoptosis by inhibiting the ROS/Ca2+-mediated mitochondrial pathway.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 1, p. 401, doi. 10.3892/mmr.2019.10267

By:

Nie, Zhigang;
Deng, Shuang;
Zhang, Lei;
Chen, Sen;
Lu, Qiang;
Peng, Hao

Publication type:

Article

Protective effect of crocin on ultraviolet B‑induced dermal fibroblast photoaging.

Published in:

Molecular Medicine Reports, 2018, v. 18, n. 2, p. 1439, doi. 10.3892/mmr.2018.9150

By:

Deng, Mingwu;
Li, Dong;
Zhang, Yichen;
Zhou, Guangdong;
Liu, Wei;
Cao, Yilin;
Zhang, Wenjie

Publication type:

Article

Antioxidant Effects of Aerobic Training and Crocin Consumption on Doxorubicin-Induced Testicular Toxicity in Rats.

Published in:

Journal of Family & Reproductive Health, 2021, v. 15, n. 1, p. 28

By:

Davoodi, Mohsen;
Bouri, Shirin Zilaei;
Ghahfarokhi, Shahla Dehghan

Publication type:

Article

Significant Effect of Crocin on the Gene Expression of MicroRNA-21 and MicroRNA-155 in Patients with Osteoarthritis.

Published in:

2022

By:

Mohebbi, Maryam;
Atabaki, Mahdi;
Tavakkol-Afshari, Jalil;
Shariati-Sarabi, Zhaleh;
Poursamimi, Javad;
Mohajeri, Seyed Ahmad;
Mohammadi, Mojgan

Publication type:

journal article

A Significant Increase in the Gene Expression of GATA-3 Following the Treatment of Osteoarthritis Patients with Crocin.

Published in:

2022

By:

Poursamimi, Javad;
Shariati-Sarabi, Zhaleh;
Tavakkol-Afshari, Jalil;
Mohammadi, Mojgan

Publication type:

journal article

Retraction Note: The Association of Cigarette Smoke Exposure with Lung Cellular Toxicity and Oxidative Stress: the Protective Role of Crocin.

Published in:

2025

By:

Radan, Maryam;
Dianat, Mahin;
Badavi, Mohammad;
Mard, Seyyed Ali;
Bayati, Vahid;
Ahmadizadeh, Masoumeh

Publication type:

Correction Notice

The Association of Cigarette Smoke Exposure with Lung Cellular Toxicity and Oxidative Stress: the Protective Role of Crocin.

Published in:

Inflammation, 2020, v. 43, n. 1, p. 135, doi. 10.1007/s10753-019-01102-1

By:

Radan, Maryam;
Dianat, Mahin;
Badavi, Mohammad;
Mard, Seyyed Ali;
Bayati, Vahid;
Ahmadizadeh, Masoumeh

Publication type:

Article

Crocin Attenuates Joint Pain and Muscle Dysfunction in Osteoarthritis Rat.

Published in:

Inflammation, 2017, v. 40, n. 6, p. 2086, doi. 10.1007/s10753-017-0648-8

By:

Lei, Min;
Guo, Chunhua;
Hua, Limei;
Xue, Sujuan;
Yu, Dan;
Zhang, Chunhua;
Wang, Dawei

Publication type:

Article

Theoretical and Experimental in vivo Study of Antioxidant Activity of Crocin in Order to Propose Novel Derivatives with Higher Antioxidant Activity and Their Delivery via Nanotubes and Nanocones.

Published in:

Inflammation, 2017, v. 40, n. 5, p. 1794, doi. 10.1007/s10753-017-0623-4

By:

Najafi, Houshang;
Yarijani, Zeynab;
Najafi, Meysam

Publication type:

Article

The Effect and Mechanisms of Proliferative Inhibition of Crocin on Human Leukaemia Jurkat Cells.

Published in:

West Indian Medical Journal, 2015, v. 64, n. 5, p. 473, doi. 10.7727/wimj.2016.053

By:

Sun, Y.;
Wang, Z.;
Wang, L.;
Wang, L-Z.;
Zang, C.;
Sun, L-R.

Publication type:

Article

The protective effect of crocin on cisplatin-induced testicular impairment in rats.

Published in:

2021

By:

Mesbahzadeh, Behzad;
Hassanzadeh-Taheri, Mohammadmehdi;
Aliparast, Mohadese-sadat;
Baniasadi, Pardis;
Hosseini, Mehran

Publication type:

journal article

Crocin, a dietary additive protects platelets from oxidative stress-induced apoptosis and inhibits platelet aggregation.

Published in:

Molecular & Cellular Biochemistry, 2013, v. 373, n. 1/2, p. 73, doi. 10.1007/s11010-012-1476-7

By:

Thushara, R.;
Hemshekhar, M.;
Santhosh, M.;
Jnaneshwari, S.;
Nayaka, S.;
Naveen, S.;
Kemparaju, K.;
Girish, K.

Publication type:

Article

The Effect of Crocin on Oxidative Stress Compared to Saffron Aqueous Extract, Glycerol and Myoinositol in Diabetic Rats.

Published in:

Journal of Nutrition & Food Security, 2025, v. 10, n. 2, p. 259, doi. 10.18502/jnfs.v10i2.18538

By:

Mohyadini, Matin;
Shirali, Saeed;
Bathaie, S. Zahra

Publication type:

Article

Crocin protects human erythrocytes from nitrite-induced methemoglobin formation and oxidative damage.

Published in:

Cell Biology International, 2016, v. 40, n. 12, p. 1320, doi. 10.1002/cbin.10687

By:

Ansari, Fariheen Aisha;
Ali, Shaikh Nisar;
Mahmood, Riaz

Publication type:

Article

Crocin improves the renal autophagy in rat experimental membranous nephropathy via regulating the SIRT1/Nrf2/HO-1 signaling pathway.

Published in:

Renal Failure, 2023, v. 45, n. 2, p. 1, doi. 10.1080/0886022X.2023.2253924

By:

Hongyan Liu;
Hong Cheng;
Hongyun Wang;
Qiong Wang;
Jun Yuan

Publication type:

Article

Effect of crocin and losartan on biochemical parameters and genes expression of FRMD3 and BMP7 in diabetic rats.

Published in:

Turkish Journal of Medical Sciences, 2023, v. 53, n. 1, p. 10, doi. 10.55730/1300-0144.5553

By:

MOHAMMADI, Yaser;
ZANGOOEI, Mohammad;
SALMANI, Fatemeh;
REZAEI FARIMANI, Azam

Publication type:

Article

Effects of crocin on experimental obesity and type-2 diabetes.

Published in:

Turkish Journal of Medical Sciences, 2016, v. 46, n. 5, p. 1593, doi. 10.3906/sag-1506-108

By:

HAZMAN, Ömer;
AKSOY, Laçine;
BÜYÜKBEN, Ahmet

Publication type:

Article

Impacts of endurance training and crocin supplementation on the apoptotic pathways in rat skeletal muscle following doxorubicin administration.

Published in:

Journal of Shahrekord University of Medical Sciences, 2024, v. 26, n. 3, p. 108, doi. 10.34172/jsums.947

By:

Eydivandi, Kavous;
Azarbayjani, Mohammad Ali;
Farzanegi, Parvin

Publication type:

Article

Effects of Crocins in the Management of Neurodegenerative Pathologies: A Review.

Published in:

Neurophysiology, 2018, v. 50, n. 4, p. 302, doi. 10.1007/s11062-018-9752-0

By:

Shaterzadeh-Yazdi, H.;
Samarghandian, S.;
Farkhondeh, T.

Publication type:

Article

Crocin has pharmacological effects against the pathological behavior of colon cancer cells by interacting with the STAT3 signaling pathway.

Published in:

Experimental & Therapeutic Medicine, 2020, v. 19, n. 2, p. 1297, doi. 10.3892/etm.2019.8329

By:

Wang, Jun;
Ke, Yupei;
Shu, Tao

Publication type:

Article

Crocin promotes apoptosis of human skin cancer cells by inhibiting the JAK/STAT pathway.

Published in:

Experimental & Therapeutic Medicine, 2018, v. 16, n. 6, p. 5079, doi. 10.3892/etm.2018.6865

By:

Wang, Gongfeng;
Zhang, Baofang;
Wang, Yanyan;
Han, Shunli;
Wang, Chenghong

Publication type:

Article

Folic acid-modified nanocrystalline cellulose for enhanced delivery and anti-cancer effects of crocin.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-64758-2

By:

Soltani, Mozhgan;
Farhadi, Amin;
Rajabi, Sarah;
Homayouni‐Tabrizi, Masoud;
Hussein, Fatimah Sameer;
Mohammadian, Navid

Publication type:

Article

Crocin Inhibits Angiogenesis and Metastasis in Colon Cancer via TNF-α/NF-kB/VEGF Pathways.

Published in:

Cells (2073-4409), 2022, v. 11, n. 9, p. N.PAG, doi. 10.3390/cells11091502

By:

Bakshi, Hamid A.;
Quinn, Gerry A.;
Nasef, Mohamed M.;
Mishra, Vijay;
Aljabali, Alaa A. A.;
El-Tanani, Mohamed;
Serrano-Aroca, Ángel;
Webba Da Silva, Mateus;
McCarron, Paul A.;
Tambuwala, Murtaza M.

Publication type:

Article

Effects of Crocin on Nox2 Expression and ROS Level of Hypoxia/Reoxygenation-induced Injury of Cardiomyocytes.

Published in:

Medicinal Plant, 2020, v. 11, n. 5, p. 71, doi. 10.19600/j.cnki.issn2152-3924.2020.05.019

By:

Chao ZENG;
Yongji XING;
Lizhi BAO;
Yuanyuan WANG;
Weiqing HU;
Jun WU;
Xiaohong LIU;
Nengwu WEN;
Jiping FAN

Publication type:

Article

Protective effects of quercetin and crocin in the kidneys and liver of obese Sprague-Dawley rats with Type 2 diabetes: Effects of quercetin and crocin on T2DM rats.

Published in:

Human & Experimental Toxicology, 2021, v. 40, n. 4, p. 661, doi. 10.1177/0960327120954521

By:

Lai, Ling-Lin;
Lu, Hui-Qin;
Li, Wen-Na;
Huang, Hui-Ping;
Zhou, He-Ying;
Leng, En-nian;
Zhang, Yue-yue

Publication type:

Article

Crocin attenuates CCl4-induced liver fibrosis via PPAR-γ mediated modulation of inflammation and fibrogenesis in rats.

Published in:

Human & Experimental Toxicology, 2020, v. 39, n. 12, p. 1639, doi. 10.1177/0960327120937048

By:

Chhimwal, J;
Sharma, S;
Kulurkar, P;
Patial, V

Publication type:

Article

Efficacy of crocin and safranal as protective agents against genotoxic stress induced by gamma radiation, urethane and procarbazine in mice.

Published in:

Human & Experimental Toxicology, 2018, v. 37, n. 1, p. 13, doi. 10.1177/0960327116689715

By:

Koul, A.;
Abraham, S. K.

Publication type:

Article

Zearalenone-induced changes in biochemical parameters, oxidative stress and apoptosis in cardiac tissue.

Published in:

Human & Experimental Toxicology, 2016, v. 35, n. 6, p. 623, doi. 10.1177/0960327115597467

By:

Salem, I. Ben;
Boussabbeh, M.;
Neffati, F.;
Najjar, M. F.;
Abid-Essefi, S.;
Bacha, H.

Publication type:

Article

Crocin attenuates cisplatin-induced liver injury in the mice.

Published in:

Human & Experimental Toxicology, 2014, v. 33, n. 8, p. 855, doi. 10.1177/0960327113511475

By:

Sun, Y;
Yang, J;
Wang, L-Z;
Sun, L-R;
Dong, Q

Publication type:

Article

OPTIMIZING THE AQUEOUS EXTRACTION OF CROCIN FROM SAFFRON AND MODELING THE KINETICS OF ITS DEGRADATION DURING STORAGE AND HEAT TREATMENT.

Published in:

Carpathian Journal of Food Science & Technology, 2024, v. 16, n. 2, p. 136, doi. 10.34302/crpjfst/2024.16.2.11

By:

BACHIR-BEY, Mostapha;
KHALED KHODJA, Yazid;
BENBOURICHE, Aicha;
CHOUALI, Malika;
DJEBELLANNOUAR, Salima;
BENCHIKH, Yassine;
KATI, Djamel Edine

Publication type:

Article

Effect of Interval and Continued Exercises with Crocin on Bax/Bcl-2 in Diabetic Obese Rats.

Published in:

Iranian Journal of Diabetes & Obesity (IJDO), 2019, v. 11, n. 3, p. 196

By:

Hassanpour, Ghobad;
Nikbakht, Hojatollah;
Azarbayjani, Mohammad Ali;
Shakeri, Nader;
Natanzi, Hossein Abed

Publication type:

Article