Works about COMPLEMENT inhibition

Results: 741

Active-Site Inhibitors of mTOR Target Rapamycin-Resistant Outputs of mTORC1 and mTORC2.

Published in:

PLoS Biology, 2009, v. 7, n. 2, p. e1000038, doi. 10.1371/journal.pbio.1000038

By:

Feldman, Morris E.;
Apsel, Beth;
Uotila, Aino;
Loewith, Robbie;
Knight, Zachary A.;
Ruggero, Davide;
Shokat, Kevan M.

Publication type:

Article

Plasma extracellular vesicles carry immune system-related peptides that predict human longevity.

Published in:

GeroScience, 2025, v. 47, n. 2, p. 1455, doi. 10.1007/s11357-024-01454-z

By:

Zhang, Xin;
Ma, Sisi;
Naz, Syeda Iffat;
Soderblom, Erik J.;
Aliferis, Constantin;
Kraus, Virginia Byers

Publication type:

Article

Ribonucleotide Reductases: Radical Chemistry and Inhibition at the Active Site.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2003, v. 22, n. 5-8, p. 519, doi. 10.1081/NCN-120021952

By:

Robins, Morris J.

Publication type:

Article

Inhibition of Transcription by bisPNA-Peptide Conjugates.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2003, v. 22, n. 5-8, p. 535, doi. 10.1081/NCN-120021953

By:

Zhao, Xin;
Kaihatsu, Kunihiro;
Corey, David R.

Publication type:

Article

Oligonucleotide N3′ → P5′ Thio-phosphoramidate Telomerase Template Antagonists as Potential Anticancer Agents.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2003, v. 22, n. 5-8, p. 577, doi. 10.1081/NCN-120021958

By:

Gryaznov, Sergei;
Asai, Akira;
Oshima, Yuko;
Yamamoto, Yoshihiro;
Pongracz, Krisztina;
Pruzan, Ronald;
Wunder, Ellen;
Piatyszek, Mieczyslaw;
Li, Shihong;
Chin, Allison;
Harley, Calvin;
Akinaga, Shiro;
Yamashita, Yoshinori

Publication type:

Article

Immunotherapeutic effects of recombinant Bacillus Calmette-Guérin containing sic gene in ex vivo and in vivo bladder cancer models.

Published in:

Investigative & Clinical Urology, 2022, v. 63, n. 2, p. 228, doi. 10.4111/icu.20210425

By:

Jung Hoon Kim;
Joongwon Choi;
Mirinae Kim;
Su Jeong Kang;
Young Wook Choi;
Se Young Choi;
Sung-Hwan Kim;
In Ho Chang

Publication type:

Article

Novel approach to antiangiogenic factors in age-related macular degeneration therapy.

Published in:

Central European Journal of Immunology, 2022, v. 47, n. 1, p. 117, doi. 10.5114/ceji.2022.113103

By:

SAMELSKA, KATARZYNA;
KUPIS, MAGDALENA;
IZDEBSKA, JUSTYNA;
KAMINSKA, ANNA;
SKOPIŃSKI, PIOTR

Publication type:

Article

Molecular mechanism of complement inhibition by the trypanosome receptor ISG65.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.88960

By:

Cook, Alexander D.;
Carrington, Mark;
Higgins, Matthew K.

Publication type:

Article

Statins Restore Endothelial Protection against Complement Activity in Obstructive Sleep Apnea: A Randomized Clinical Trial.

Published in:

Annals of the American Thoracic Society, 2023, v. 20, n. 7, p. 1029, doi. 10.1513/AnnalsATS.202209-761OC

By:

Shah, Riddhi;
Patel, Neha;
Emin, Memet;
Celik, Yeliz;
Jimenez, Alondra;
Su Gao;
Garfinkel, Jared;
Ying Wei;
Jelic, Sanja

Publication type:

Article

SARS‐CoV‐2 targeting by RNAi and host complement inhibition: A two‐pronged subterfuge for COVID‐19 treatment.

Published in:

Immunity, Inflammation & Disease, 2022, v. 10, n. 1, p. 22, doi. 10.1002/iid3.549

By:

Naqvi, Raza Ali;
Shukla, Deepak;
Naqvi, Afsar R.

Publication type:

Article

Treatment of Presumptive Rejection After Orthotopic Pig‐to‐Baboon Cardiac Xenotransplantation.

Published in:

Xenotransplantation, 2025, v. 32, n. 2, p. 1, doi. 10.1111/xen.70044

By:

Mitchell, Chace B.;
Neal, Sarah J.;
Simmons, Joe H.;
Chitta, Sriram;
Cooper, David K. C.;
Cleveland, David C.;
Cleveland, John D.

Publication type:

Article

Antibody‐mediated rejection in xenotransplantation: Can it be prevented or reversed?

Published in:

Xenotransplantation, 2023, v. 30, n. 4, p. 1, doi. 10.1111/xen.12816

By:

Habibabady, Zahra;
McGrath, Gannon;
Kinoshita, Kohei;
Maenaka, Akihiro;
Ikechukwu, Ileka;
Elias, Gabriela F.;
Zaletel, Tjasa;
Rosales, Ivy;
Hara, Hidetaka;
Pierson, Richard N.;
Cooper, David K. C.

Publication type:

Article

A perspective on the potential detrimental role of inflammation in pig orthotopic heart xenotransplantation.

Published in:

Xenotransplantation, 2021, v. 28, n. 4, p. 1, doi. 10.1111/xen.12687

By:

Thompson, Charles P.;
Jagdale, Abhijit;
Walcott, Gregory;
Iwase, Hayato;
Foote, Jeremy B.;
Cron, Randall Q.;
Hara, Hidetaka;
Cleveland, David C.;
Cooper, David K. C.

Publication type:

Article

Recent progress and remaining hurdles toward clinical xenotransplantation.

Published in:

Xenotransplantation, 2021, v. 28, n. 3, p. 1, doi. 10.1111/xen.12681

By:

Meier, Raphael P.H.;
Longchamp, Alban;
Mohiuddin, Muhammad;
Manuel, Oriol;
Vrakas, Georgios;
Maluf, Daniel G.;
Buhler, Leo H.;
Muller, Yannick D.;
Pascual, Manuel

Publication type:

Article

Effects of pharmacological intervention on coagulopathy and organ function in xenoperfused kidneys.

Published in:

Xenotransplantation, 2008, v. 15, n. 1, p. 46, doi. 10.1111/j.1399-3089.2008.00443.x

By:

Ramackers, Wolf;
Friedrich, Lars;
Tiede, Andreas;
Bergmann, Sabine;
Schuettler, Wolfgang;
Schuerholz, Tobias;
Mengel, Michael;
Goudeva, Lili;
Ganser, Arnold;
Klempnauer, Jürgen;
Piepenbrock, Siegfried;
Winkler, Michael

Publication type:

Article

Hypodermin A, a new inhibitor of human complement for the prevention of xenogeneic hyperacute rejection.

Published in:

Xenotransplantation, 2003, v. 10, n. 3, p. 267, doi. 10.1034/j.1399-3089.2003.02030.x

By:

Malassagne, B.;
Regimbeau, J. M.;
Taboit, F.;
Troalen, F.;
Chéreau, C.;
Moiré, N.;
Attal, J.;
Batteux, F.;
Conti, F.;
Calmus, Y.;
Houssin, D.;
Boulard, C.;
Houdebine, L. M.;
Weill, B.

Publication type:

Article

Hyperacute lung rejection in the pig-to-human model. 2. Synergy between soluble and membrane complement inhibition.

Published in:

Xenotransplantation, 2003, v. 10, n. 2, p. 120, doi. 10.1034/j.1399-3089.2003.01102.x

By:

Azimzadeh, A;
Zorn, G. L;
Blair, K. S. A;
Zhang, J. P;
Pfeiffer, S;
Harrison, R. A;
Cozzi, E;
White, D. J. G;
Pierson, R. N

Publication type:

Article

Comparative analysis of three genetic modifications designed to inhibit human serum‐mediated cytolysis.

Published in:

Xenotransplantation, 1999, v. 6, n. 1, p. 6, doi. 10.1034/j.1399-3089.1999.00004.x

By:

Costa, Cristina;
Zhao, Lisa;
Decesare, Stephanie;
Fodor, William L.

Publication type:

Article

Successful pharmacological intervention at different levels of the complement system in an in vitro complement fixation model for bullous pemphigoid.

Published in:

Experimental Dermatology, 2023, v. 32, n. 5, p. 632, doi. 10.1111/exd.14755

By:

Giang, Jenny;
van Doorn, Martijn B. A.;
Diercks, Gilles F. H.;
de Cordoba, Santiago Rodriguez;
van den Bosch, Thierry P. P.;
Schreurs, Marco W. J.;
Poppelaars, Felix;
Damman, Jeffrey

Publication type:

Article

Integrating complement into the molecular pathogenesis of Hidradenitis Suppurativa.

Published in:

Experimental Dermatology, 2020, v. 29, n. 1, p. 86, doi. 10.1111/exd.14056

By:

Grand, David;
Navrazhina, Kristina;
Frew, John W.

Publication type:

Article

Registered trials on novel therapies for myasthenia gravis: a cross-sectional study on ClinicalTrials.gov.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-52539-w

By:

Li, Xingyue;
Chen, Jinxin;
Wang, Youtao;
Zheng, Siwei;
Wan, Kun;
Liu, Xiaodong

Publication type:

Article

Adaptation of Staphylococcus aureus to the Human Skin Environment Identified Using an ex vivo Tissue Model.

Published in:

Frontiers in Microbiology, 2021, v. 12, p. 1, doi. 10.3389/fmicb.2021.728989

By:

Burian, Marc;
Plange, Johanna;
Schmitt, Laurenz;
Kaschke, Anke;
Marquardt, Yvonne;
Huth, Laura;
Baron, Jens M.;
Hornef, Mathias W.;
Wolz, Christiane;
Yazdi, Amir S.

Publication type:

Article

Corrigendum: Complement System Inhibition Modulates the Pro-Inflammatory Effects of a Snake Venom Metalloproteinase.

Published in:

2019

By:

Luchini, Lygia Samartin Gonçalves;
Pidde, Giselle;
Squaiella-Baptistão, Carla Cristina;
Tambourgi, Denise V.

Publication type:

Correction Notice

Anti-complement Treatment for Paroxysmal Nocturnal Hemoglobinuria: Time for Proximal Complement Inhibition? A Position Paper From the SAAWP of the EBMT.

Published in:

Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.01157

By:

Risitano, Antonio M.;
Marotta, Serena;
Ricci, Patrizia;
Marano, Luana;
Frieri, Camilla;
Cacace, Fabiana;
Sica, Michela;
Kulasekararaj, Austin;
Calado, Rodrigo T.;
Scheinberg, Phillip;
Notaro, Rosario;
Peffault de Latour, Regis

Publication type:

Article

Chimeric Proteins Containing MAP-1 and Functional Domains of C4b-Binding Protein Reveal Strong Complement Inhibitory Capacities.

Published in:

Frontiers in Immunology, 2018, p. N.PAG, doi. 10.3389/fimmu.2018.01945

By:

Hertz, Cecilie E.;
Bayarri-Olmos, Rafael;
Kirketerp-Møller, Nikolaj;
van Putten, Sander;
Pilely, Katrine;
Skjoedt, Mikkel-Ole;
Garred, Peter

Publication type:

Article

Be on Target: Strategies of Targeting Alternative and Lectin Pathway Components in Complement-Mediated Diseases.

Published in:

Frontiers in Immunology, 2018, p. N.PAG, doi. 10.3389/fimmu.2018.01851

By:

Dobó, József;
Kocsis, Andrea;
Gál, Péter

Publication type:

Article

Human lung cancer cell lines express cell membrane complement inhibitory proteins and are extremely resistant to complement-mediated lysis; a comparison with normal human respiratory epithelium in vitro, and an insight into mechanism(s) of resistance.

Published in:

Clinical & Experimental Immunology, 1998, v. 113, n. 2, p. 173, doi. 10.1046/j.1365-2249.1998.00581.x

By:

Varsano;
Rashkovsky;
Shapiro;
Ophir;
Mark-Bentankur;
Varsano, Shabtai

Publication type:

Article

Complement-regulatory protein expression and activation of complement cascade on erythrocytes...

Published in:

Clinical & Experimental Immunology, 1998, v. 111, n. 1, p. 102, doi. 10.1046/j.1365-2249.1998.00449.x

By:

Arora;
Kumar;
Das;
Srivastava;
Srivastava

Publication type:

Article

Tumour cell killing using chemically engineered antibody constructs specific for tumour cells and the complement inhibitor CD59.

Published in:

Clinical & Experimental Immunology, 1997, v. 107, n. 2, p. 364, doi. 10.1111/j.1365-2249.1997.265-ce1156.x

By:

Harris, C. L.;
Kan, K. S.;
Stevenson, G. T.;
Morgan, B. P.

Publication type:

Article

Functional activity of the membrane-associated complement inhibitor CD59 in a pig-to-human in vitro model for hyperacute xenograft rejection.

Published in:

Clinical & Experimental Immunology, 1995, v. 102, n. 3, p. 589

By:

Heckl-Östreicher, B.;
Binder, R.;
Kirschfink, M.

Publication type:

Article

A component of the medicinal herb ephedra blocks activation in the classical and alternative pathways of complement.

Published in:

Clinical & Experimental Immunology, 1995, v. 102, n. 3, p. 582

By:

Ling, M.;
Piddlesden, S. J.;
Morgan, B. P.

Publication type:

Article

Characterization of alternative pathway inhibition by a serum derived, low molecular weight complement inhibitor.

Published in:

Clinical & Experimental Immunology, 1984, v. 55, n. 1, p. 166

By:

Baker, Patricia J.;
Parker, C. J.;
Osofsky, S. G.

Publication type:

Article

Humoral and cell-mediated immune responses in chronic typhoid carriers.

Published in:

Clinical & Experimental Immunology, 1982, v. 49, n. 1, p. 34

By:

Dham, S. K.;
Thompson, R. A.

Publication type:

Article

Isolation and characterization of a low molecular weight complement inhibitor present in normal human serum.

Published in:

Clinical & Experimental Immunology, 1981, v. 43, n. 3, p. 549

By:

Baker, Patricia J.;
Osofsky, S. G.

Publication type:

Article

Corrigendum.

Published in:: Cellular Microbiology, 2021, v. 23, n. 1, p. 1, doi. 10.1111/cmi.13286
Publication type:: Article

A Case of Atypical Hemolytic Uremic Syndrome With a Complement Factor I Mutation Triggered by a Femoral Neck Fracture.

Published in:

Nephrology, 2025, v. 30, n. 3, p. 1, doi. 10.1111/nep.70010

By:

Kano, Toshiki;
Io, Hiroaki;
Sasaki, Yu;
Muto, Masahiro;
Muto, Sayaka;
Ogiwara, Kei;
Ikeda, Arisa;
Iwasaki, Hiroyuki;
Suzuki, Yusuke

Publication type:

Article

Utilizing complement inhibition in IgA nephropathy.

Published in:

Nephrology, 2024, v. 29, p. 44, doi. 10.1111/nep.14347

By:

Lafayette, Richard

Publication type:

Article

Exploring treatment strategies for paroxysmal nocturnal hemoglobinuria: an overview of registered clinical trials.

Published in:

Current Medical Research & Opinion, 2024, v. 40, n. 6, p. 935, doi. 10.1080/03007995.2024.2354533

By:

Peixoto, Vanda P.;
Prudêncio, Cristina;
Vieira, Mónica

Publication type:

Article

Biology-guided deep learning predicts prognosis and cancer immunotherapy response.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-40890-x

By:

Jiang, Yuming;
Zhang, Zhicheng;
Wang, Wei;
Huang, Weicai;
Chen, Chuanli;
Xi, Sujuan;
Ahmad, M. Usman;
Ren, Yulan;
Sang, Shengtian;
Xie, Jingjing;
Wang, Jen-Yeu;
Xiong, Wenjun;
Li, Tuanjie;
Han, Zhen;
Yuan, Qingyu;
Xu, Yikai;
Xing, Lei;
Poultsides, George A.;
Li, Guoxin;
Li, Ruijiang

Publication type:

Article

Treatment of Acquired C--1--Inhibitor Deficiency with Danazol.

Published in:

1977

By:

Hauptmann, Georges;
Mayer, Simone;
Lang, Jean-Marie;
Oberling, Francis;
Mayer, Georges

Publication type:

Case Study

Correction: Complement inhibitor CSMD1 modulates epidermal growth factor receptor oncogenic signaling and sensitizes breast cancer cells to chemotherapy.

Published in:

2023

By:

Gialeli, Chrysostomi;
Tuysuz, Emre Can;
Staaf, Johan;
Guleed, Safa;
Paciorek, Veronika;
Mörgelin, Matthias;
Papadakos, Konstantinos S.;
Blom, Anna M.

Publication type:

Correction Notice

Complement inhibitor and anti-VEGF may be safe for AMD treatment.

Published in:

Ocular Surgery News, 2010, v. 28, n. 11, p. 20

By:

Hasson, Matt;
Mullin, David W.

Publication type:

Article

Complement inhibitor shows promise in treating wet AMD.

Published in:

Ocular Surgery News, 2009, v. 27, n. 17, p. 28

By:

Hasson, Matt

Publication type:

Article

In vitro Inhibition of Canine Complement‐Mediated Hemolysis.

Published in:

Journal of Veterinary Internal Medicine, 2018, v. 32, n. 1, p. 142, doi. 10.1111/jvim.14871

By:

Hernandez, D. M.;
Behling‐Kelly, E.;
Goggs, R.

Publication type:

Article

Recomendaciones para el diagnóstico y tratamiento de las vasculitis asociadas a anticuerpos anticitoplasma de neutrófilo.

Published in:

Nefrologia, 2025, v. 45, n. 1, p. 15, doi. 10.1016/j.nefro.2024.07.004

By:

Morales, Enrique;
Rúa-Figueroa, Iñigo;
Rubio, José Luis Callejas;
Ávila Bernabéu, Ana;
Blanco Alonso, Ricardo;
Cid Xutgla, Maria C.;
Fernández Juárez, Gema;
Mena-Vázquez, Natalia;
Ríos Blanco, Juan José;
Escola, Joaquín Manrique;
Narváez García, F. Javier;
Sopeña, Bernardo;
Quintana Porras, Luis F.;
Romero-Yuste, Susana;
Solans Laqué, Roser

Publication type:

Article

Linoleic Acid Derivative DCP-LA Protects Neurons from Oxidative Stress-Induced Apoptosis by Inhibiting Caspase-3/-9 Activation.

Published in:

Neurochemical Research, 2010, v. 35, n. 5, p. 712, doi. 10.1007/s11064-010-0124-4

By:

Yaguchi, Takahiro;
Fujikawa, Hirokazu;
Nishizaki, Tomoyuki

Publication type:

Article

Transportable and Non-transportable Inhibitors of L-glutamate Uptake Produce Astrocytic Stellation and Increase EAAT2 Cell Surface Expression.

Published in:

Neurochemical Research, 2010, v. 35, n. 5, p. 735, doi. 10.1007/s11064-010-0130-6

By:

Lau, Chew L.;
Beart, Philip M.;
O'Shea, Ross D.

Publication type:

Article

Inhibition of ATP-Induced Ca<sup>2+</sup> Influx by Corticosterone in Dorsal Root Ganglion Neurons.

Published in:

Neurochemical Research, 2010, v. 35, n. 5, p. 804, doi. 10.1007/s11064-010-0138-y

By:

Xiaohong Liu;
Junwei Zeng;
Yandong Zhao;
Zhi Xiao;
Chuanqing Fang;
Huaizhen Ruan

Publication type:

Article

P-MAPA, a Fungi-Derived Immunomodulatory Compound, Induces a Proinflammatory Response in a Human Whole Blood Model.

Published in:

Mediators of Inflammation, 2020, p. 1, doi. 10.1155/2020/8831389

By:

Gonçalves, Mariana Torrente;
Squaiella-Baptistão, Carla Cristina;
Pidde, Giselle;
Lopes, Priscila Hess;
da Silva Nunes, Iseu;
Tambourgi, Denise V.

Publication type:

Article

P-MAPA, a Fungi-Derived Immunomodulatory Compound, Induces a Proinflammatory Response in a Human Whole Blood Model.

Published in:

Mediators of Inflammation, 2020, p. 1, doi. 10.1155/2020/8831389

By:

Gonçalves, Mariana Torrente;
Squaiella-Baptistão, Carla Cristina;
Pidde, Giselle;
Lopes, Priscila Hess;
da Silva Nunes, Iseu;
Tambourgi, Denise V.

Publication type:

Article