Works matching DE "CHOLINE kinase"

Results: 33

Kinase joins the chaperone club: Androgen-regulated kinome reveals choline kinase alpha as a potential drug target in prostate cancer.

Published in:

2016

By:

Asim, Mohammad;
Massie, Charlie E.;
Neal, David E.

Publication type:

Opinion

CHKA mediates the poor prognosis of lung adenocarcinoma and acts as a prognostic indicator.

Published in:

Oncology Letters, 2016, v. 12, n. 3, p. 1849, doi. 10.3892/ol.2016.4810

By:

LI ZHANG;
PING CHEN;
SHEN YANG;
GUODONG LI;
WENTAO BAO;
PENG WU;
SHUJUAN JIANG

Publication type:

Article

Degradable Dextran Nanopolymer as a Carrier for Choline Kinase (ChoK) siRNA Cancer Therapy.

Published in:

Nanomaterials (2079-4991), 2016, v. 6, n. 2, p. 34, doi. 10.3390/nano6020034

By:

Zhihang Chen;
Krishnamachary, Balaji;
Bhujwalla, Zaver M.

Publication type:

Article

KDM2B regulates choline kinase expression and neuronal differentiation of neuroblastoma cells.

Published in:

PLoS ONE, 2019, v. 14, n. 01, p. 1, doi. 10.1371/journal.pone.0210207

By:

Domizi, Pablo;
Malizia, Florencia;
Chazarreta-Cifre, Lorena;
Diacovich, Lautaro;
Banchio, Claudia

Publication type:

Article

Parallel Colorimetric Quantification of Choline and Phosphocholine as a Method for Studying Choline Kinase Activity in Complex Mixtures.

Published in:

Antibiotics (2079-6382), 2018, v. 7, n. 1, p. 24, doi. 10.3390/antibiotics7010024

By:

Zimmerman, Tahl;
Ibrahim, Salam A.

Publication type:

Article

Choline Kinase, A Novel Drug Target for the Inhibition of Streptococcus pneumoniae.

Published in:

Antibiotics (2079-6382), 2017, v. 6, n. 4, p. 20, doi. 10.3390/antibiotics6040020

By:

Zimmerman, Tahl;
Ibrahim, Salam

Publication type:

Article

Structural and Enzymatic Characterization of the Choline Kinase LicA from Streptococcus pneumoniae.

Published in:

PLoS ONE, 2015, v. 10, n. 3, p. 1, doi. 10.1371/journal.pone.0120467

By:

Wang, Lei;
Jiang, Yong-Liang;
Zhang, Jing-Ren;
Zhou, Cong-Zhao;
Chen, Yuxing

Publication type:

Article

Ets and GATA Transcription Factors Play a Critical Role in PMA-Mediated Repression of the ckβ Promoter via the Protein Kinase C Signaling Pathway.

Published in:

PLoS ONE, 2014, v. 9, n. 12, p. 1, doi. 10.1371/journal.pone.0113485

By:

Kuan, Chee Sian;
Yee, Yoke Hiang;
See Too, Wei Cun;
Few, Ling Ling

Publication type:

Article

Choline Kinase Alpha and Hexokinase-2 Protein Expression in Hepatocellular Carcinoma: Association with Survival.

Published in:

PLoS ONE, 2012, v. 7, n. 10, p. 1, doi. 10.1371/journal.pone.0046591

By:

Kwee, Sandi A.;
Hernandez, Brenda;
Chan, Owen;
Wong, Linda;
Xin-Yuan Guan

Publication type:

Article

Differential Role of Human Choline Kinase α and β Enzymes in Lipid Metabolism: Implications in Cancer Onset and Treatment.

Published in:: PLoS ONE, 2009, v. 4, n. 11, p. 1, doi. 10.1371/journal.pone.0007819
Publication type:: Article

New splicing mutation in the choline kinase beta (CHKB) gene causing a muscular dystrophy detected by whole-exome sequencing.

Published in:

Journal of Human Genetics, 2015, v. 60, n. 6, p. 305, doi. 10.1038/jhg.2015.20

By:

Oliveira, Jorge;
Negrão, Luís;
Fineza, Isabel;
Taipa, Ricardo;
Melo-Pires, Manuel;
Fortuna, Ana Maria;
Gonçalves, Ana Rita;
Froufe, Hugo;
Egas, Conceição;
Santos, Rosário;
Sousa, Mário

Publication type:

Article

Investigation of discriminant metabolites in tamoxifen-resistant and choline kinase-alpha-downregulated breast cancer cells using <sup>1</sup>H-nuclear magnetic resonance spectroscopy.

Published in:

PLoS ONE, 2017, v. 12, n. 6, p. 1, doi. 10.1371/journal.pone.0179773

By:

Kim, Hoe Suk;
Tian, Lianji;
Kim, Hyeonjin;
Moon, Woo Kyung

Publication type:

Article

Protein τ-Mediated Effects on Rat Hippocampal Choline Transporters CHT1 and τ-Amyloid β Interactions.

Published in:

Neurochemical Research, 2013, v. 38, n. 9, p. 1949, doi. 10.1007/s11064-013-1101-5

By:

Kristofikova, Zdena;
Ripova, Daniela;
Hegnerová, Katerina;
Sirova, Jana;
Homola, Jiri

Publication type:

Article

Identification and validation of novel and more effective choline kinase inhibitors against Streptococcus pneumoniae.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-72165-6

By:

Zimmerman, Tahl;
Chasten, Valerie;
Lacal, Juan Carlos;
Ibrahim, Salam A.

Publication type:

Article

An Amperometric Biosensor for the Determination of Bacterial Sepsis Biomarker, Secretory Phospholipase Group 2-IIA Using a Tri-Enzyme System.

Published in:

Sensors (14248220), 2018, v. 18, n. 3, p. 686, doi. 10.3390/s18030686

By:

Nik Mansor, Nik Nurhanan;
Leong, Tan Toh;
Safitri, Eka;
Futra, Dedi;
Ahmad, Nurul Saadah;
Nasuruddin, Dian Nasriana;
Itnin, Azlin;
Zaini, Ida Zarina;
Arifin, Khaizurin Tajul;
Heng, Lee Yook;
Hassan, Nurul Izzaty

Publication type:

Article

The role of phosphatidylcholine and choline metabolites to cell proliferation and survival.

Published in:

Critical Reviews in Biochemistry & Molecular Biology, 2013, v. 48, n. 1, p. 20, doi. 10.3109/10409238.2012.735643

By:

Ridgway, Neale D.

Publication type:

Article

Correlation between Choline Peak at MR Spectroscopy and Calcium-Sensing Receptor Expression Level in Breast Cancer: A Preliminary Clinical Study.

Published in:

Molecular Imaging & Biology, 2015, v. 17, n. 4, p. 548, doi. 10.1007/s11307-015-0823-y

By:

Baio, Gabriella;
Rescinito, Giuseppe;
Rosa, Francesca;
Pace, Daniele;
Boccardo, Simona;
Basso, Luca;
Salvi, Sandra;
Calabrese, Massimo;
Truini, Mauro;
Neumaier, Carlo

Publication type:

Article

Pharmacophore-Based Virtual Screening to Discover New Active Compounds for Human Choline Kinase α1.

Published in:

Molecular Informatics, 2015, v. 34, n. 6/7, p. 458, doi. 10.1002/minf.201400140

By:

Serrán‐Aguilera, Lucía;
Nuti, Roberto;
López‐Cara, Luisa C.;
Mezo, Miguel Á. Gallo;
Macchiarulo, Antonio;
Entrena, Antonio;
Hurtado‐Guerrero, Ramón

Publication type:

Article

New more polar symmetrical choline kinase inhibitors II: study of setting up a new scaffold for the cancer therapy.

Published in:

Journal of Biological Research / Bollettino della Società Italiana di Biologia Sperimentale, 2015, v. 88, n. 1, p. 92

By:

López-Cara, L. C.;
Castro-Navas, F.;
Aiello, S.;
Gallo-Mezo, M. A.;
Espinosa, A.;
Entrena-Guadix, A.

Publication type:

Article

Downregulation of human choline kinase α gene expression by miR-876‑5p.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 5, p. 7442, doi. 10.3892/mmr.2018.8762

By:

Khan, Sharzehan Mohamad Ayub;
Few, Ling Ling;
Too, Wei Cun See

Publication type:

Article

Expression profiling of choline and ethanolamine kinases in MCF7, HCT116 and HepG2 cells, and the transcriptional regulation by epigenetic modification.

Published in:

Molecular Medicine Reports, 2015, v. 11, n. 1, p. 611, doi. 10.3892/mmr.2014.2707

By:

CHUA SIANG LING;
KHOO BOON YIN;
SEE TOO WEI CUN;
FEW LING LING

Publication type:

Article

Key Players in Choline Metabolic Reprograming in Triple-Negative Breast Cancer.

Published in:

Frontiers in Oncology, 2016, v. 6, p. 1, doi. 10.3389/fonc.2016.00205

By:

Iorio, Egidio;
Cecchetti, Serena;
Carpinelli, Giulia;
Canese, Rossella;
Podo, Franca;
Caramujo, Maria José;
Spadaro, Francesca

Publication type:

Article

Activation of Phosphatidylcholine-Specific Phospholipase C in Breast and Ovarian Cancer: Impact on MRS-Detected Choline Metabolic Profile and Perspectives for Targeted Therapy.

Published in:

Frontiers in Oncology, 2016, p. 1, doi. 10.3389/fonc.2016.00171

By:

Podo, Franca;
Paris, Luisa;
Cecchetti, Serena;
Spadaro, Francesca;
Abalsamo, Laura;
Ramoni, Carlo;
Ricci, Alessandro;
Pisanu, Maria Elena;
Sardanelli, Francesco;
Canese, Rossella;
Iorio, Egidio;
Schillaci, Orazio;
Chakraborty, Goutam

Publication type:

Article

Choline Metabolism Alteration: A Focus on Ovarian Cancer.

Published in:

Frontiers in Oncology, 2016, p. 1, doi. 10.3389/fonc.2016.00153

By:

Bagnoli, Marina;
Granata, Anna;
Nicoletti, Roberta;
Mezzanzanica, Delia;
Canevari, Silvana;
Krishnamachary, Balaji;
Bhujwalla, Zaver M.;
Canese, Rossella;
Podo, Franca;
Iorio, Egidio;
Schillaci, Orazio;
Aloj, Luigi;
Millo, Corina

Publication type:

Article

Phosphorylation of Human Choline Kinase Beta by Protein Kinase A: Its Impact on Activity and Inhibition.

Published in:

PLoS ONE, 2016, v. 11, n. 5, p. 1, doi. 10.1371/journal.pone.0154702

By:

Chang, Ching Ching;
Few, Ling Ling;
Konrad, Manfred;
See Too, Wei Cun

Publication type:

Article

Downregulation of Choline Kinase-Alpha Enhances Autophagy in Tamoxifen-Resistant Breast Cancer Cells.

Published in:

PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0141110

By:

Kim, Hoe Suk;
Tian, Lianji;
Jung, Minji;
Choi, Sul Ki;
Sun, Yujin;
Kim, Hyeonjin;
Moon, Woo Kyung

Publication type:

Article

Synthesis of trans-6-(4-chlorobenzoyl)-7-(aryl)-1,3-dimethyl-6,7-dihydrofuro[3,2-d]pyrimidine-2,4-diones using choline hydroxide as an efficient catalyst in an aqueous medium.

Published in:

Journal of Chemical Research, 2017, v. 41, n. 3, p. 139, doi. 10.3184/174751917X14859570937794

By:

Salari, Maryam;
Hassanabadi, Alireza;
Mosslemin, Mohammad H.

Publication type:

Article

Molecular basis for the interaction between human choline kinase alpha and the SH3 domain of the c-Src tyrosine kinase.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-53447-0

By:

Kall, Stefanie L.;
Whitlatch, Kindra;
Smithgall, Thomas E.;
Lavie, Arnon

Publication type:

Article

Functional interactions between Choline kinase α, epidermal growth factor receptor and c-Src in breast cancer cell proliferation.

Published in:

Oncogene, 2012, v. 31, n. 11, p. 1431, doi. 10.1038/onc.2011.332

By:

Miyake, T;
Parsons, S J

Publication type:

Article

Genomic copy number variation of the CHKB gene alters gene expression and affects growth traits of Chinese domestic yak (Bos grunniens) breeds.

Published in:

Molecular Genetics & Genomics, 2019, v. 294, n. 3, p. 549, doi. 10.1007/s00438-018-01530-y

By:

Goshu, Habtamu Abera;
Chu, Min;
Xiaoyun, Wu;
Pengjia, Bao;
Zhi, Ding Xue;
Yan, Ping

Publication type:

Article

Intergenic Sequence between Arabidopsis Caseinolytic Protease B-Cytoplasmic/Heat Shock Protein100 and Choline Kinase Genes Functions as a Heat-Inducible Bidirectional Promoter.

Published in:

Plant Physiology, 2014, v. 166, n. 3, p. 1646, doi. 10.1104/pp.114.250787

By:

Mishra, Ratnesh Chandra;
Grover, Anil

Publication type:

Article

Composite Aromatic Boxes for Enzymatic Transformations of Quaternary Ammonium Substrates.

Published in:

Angewandte Chemie International Edition, 2014, v. 53, n. 49, p. 13471, doi. 10.1002/anie.201408246

By:

Nagy, Gergely N.;
Marton, Lívia;
Contet, Alicia;
Ozohanics, Olivér;
Ardelean, Laura‐Mihaela;
Révész, Ágnes;
Vékey, Károly;
Irimie, Florin Dan;
Vial, Henri;
Cerdan, Rachel;
Vértessy, Beáta G.

Publication type:

Article

Choline kinase-alpha by regulating cell aggressiveness and drug sensitivity is a potential druggable target for ovarian cancer.

Published in:

British Journal of Cancer, 2014, v. 110, n. 2, p. 330, doi. 10.1038/bjc.2013.729

By:

Granata, A;
Nicoletti, R;
Tinaglia, V;
De Cecco, L;
Pisanu, M E;
Ricci, A;
Podo, F;
Canevari, S;
Iorio, E;
Bagnoli, M;
Mezzanzanica, D

Publication type:

Article