Works matching DE "CHIRAL drugs"

Results: 585

Colorimetric Sensors for Recognition of Chiral Drugs Using Gold Nanoparticles.

Published in:

Chirality, 2025, v. 37, n. 6, p. 1, doi. 10.1002/chir.70039

By:

Obaid, Asma;
Maslamani, Nujud;
Teqah, Ameerah;
Siddiq, Hind;
Ghubayra, Reem;
Mousa, Ibtisam;
Jamil, Arniza Khairani Mohd;
Mohamad, Sharifah

Publication type:

Article

Chiral substrate-induced chiral covalent organic framework membranes for enantioselective separation of macromolecular drug.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60572-0

By:

Gao, Xiaoyue;
Ben, Teng

Publication type:

Article

Rapid Access to Chiral and Tripodal Cavitands from β‐Pinene.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 72, p. 1, doi. 10.1002/chem.202202416

By:

Wang, Xiuze;
Pavlović, Radoslav Z.;
Finnegan, Tyler J.;
Karmakar, Pratik;
Moore, Curtis E.;
Badjić, Jovica D.

Publication type:

Article

Isoleucine Residues Determine Chiral Discrimination of Odorant‐Binding Protein.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 40, p. 8720, doi. 10.1002/chem.202000872

By:

Zaremska, Valeriia;
Tan, Jiajun;
Lim, Sierin;
Knoll, Wolfgang;
Pelosi, Paolo

Publication type:

Article

A Novel Mechanism of Preferential Enrichment Phenomenon Observed for the Cocrystal of (RS)‐2‐{4‐[(4‐Chlorophenoxy)methyl]phenoxy}propionic Acid and Isonicotinamide.

Published in:

Chemistry - A European Journal, 2019, v. 25, n. 71, p. 16405, doi. 10.1002/chem.201904130

By:

Takahashi, Hiroki;
Numao, Yuki;
Motokawa, Junko;
Clevers, Simon;
Coquerel, Gérard;
Tsue, Hirohito;
Tamura, Rui

Publication type:

Article

Kinetic Resolution of Allyl Fluorides by Enantioselective Allylic Trifluoromethylation Based on Silicon-Assisted CF Bond Cleavage.

Published in:

Angewandte Chemie, 2014, v. 126, n. 2, p. 527, doi. 10.1002/ange.201308071

By:

Nishimine, Takayuki;
Fukushi, Kazunobu;
Shibata, Naoyuki;
Taira, Hiromi;
Tokunaga, Etsuko;
Yamano, Akihito;
Shiro, Motoo;
Shibata, Norio

Publication type:

Article

Hindered Aryllithium Reagents as Partners in Palladium-Catalyzed Cross-Coupling: Synthesis of Tri- and Tetra- ortho-Substituted Biaryls under Ambient Conditions.

Published in:

Angewandte Chemie, 2013, v. 125, n. 50, p. 13571, doi. 10.1002/ange.201306427

By:

Giannerini, Massimo;
Hornillos, Valentín;
Vila, Carlos;
Fañanás ‐ Mastral, Martín;
Feringa, Ben L.

Publication type:

Article

Synthesis of Bulky Cellulose Derivatives for Efficient Enantioselective Fluorescent Sensing.

Published in:

Cellulose, 2024, v. 31, n. 9, p. 5779, doi. 10.1007/s10570-024-05959-w

By:

Wang, Weiqi;
Wang, Fan;
Wang, Yuqing;
Zhang, Lili;
Okamoto, Yoshio;
Shen, Jun

Publication type:

Article

A comprehensive review on the development of chiral Cu, Ni, and Zn complexes as pharmaceutical agents over the past decades: Synthesis, molecular structure and biological activity.

Published in:

Medicinal Research Reviews, 2025, v. 45, n. 2, p. 654, doi. 10.1002/med.22083

By:

Kazemi, Zahra;
Moini, Nakisa;
Rudbari, Hadi Amiri;
Micale, Nicola

Publication type:

Article

Increased NADPH availability in Escherichia coli: improvement of the product per glucose ratio in reductive whole-cell biotransformation.

Published in:

Applied Microbiology & Biotechnology, 2011, v. 92, n. 5, p. 929, doi. 10.1007/s00253-011-3374-4

By:

Siedler, Solvej;
Bringer, Stephanie;
Bott, Michael

Publication type:

Article

A review-biosynthesis of optically pure ethyl ( S)-4-chloro-3-hydroxybutanoate ester: recent advances and future perspectives.

Published in:

Applied Microbiology & Biotechnology, 2011, v. 89, n. 3, p. 513, doi. 10.1007/s00253-010-2942-3

By:

Qi Ye;
Pingkai Ouyang;
Hanjie Ying

Publication type:

Article

Bioproduction of chiral mandelate by enantioselective deacylation of α-acetoxyphenylacetic acid using whole cells of newly isolated Pseudomonas sp. ECU1011.

Published in:

Applied Microbiology & Biotechnology, 2010, v. 86, n. 1, p. 83, doi. 10.1007/s00253-009-2286-z

By:

Xin Ju;
Hui-Lei Yu;
Jiang Pan;
Dong-Zhi Wei;
Jian-He Xu

Publication type:

Article

Uses and production of chiral 3-hydroxy-γ-butyrolactones and structurally related chemicals.

Published in:

Applied Microbiology & Biotechnology, 2009, v. 84, n. 5, p. 817, doi. 10.1007/s00253-009-2143-0

By:

Sang-Hyun Lee;
Oh-Jin Park

Publication type:

Article

A chemoenzymatic approach to the synthesis of enantiomerically pure ( S)-3-hydroxy-γ-butyrolactone.

Published in:

Applied Microbiology & Biotechnology, 2008, v. 79, n. 3, p. 355, doi. 10.1007/s00253-008-1439-9

By:

Lee, Sang-Hyun;
Park, Oh-Jin;
Uh, Hong-Sun

Publication type:

Article

A new chiral derivatizing agent for the HPLC separation of α-amino acids on a standard reverse-phase column.

Published in:

Amino Acids, 2011, v. 40, n. 2, p. 527, doi. 10.1007/s00726-010-0665-5

By:

Kotthaus, A.;
Altenbach, H.-J.

Publication type:

Article

Application of ( S)- N-(4-Nitrophenoxycarbonyl) phenylalanine methoxyethyl ester as a chiral derivatizing reagent for reversed-phase high-performance liquid chromatographic separation of diastereomers of amino alcohols, non-protein amino acids, and PenA.

Published in:

Amino Acids, 2010, v. 39, n. 2, p. 549, doi. 10.1007/s00726-010-0472-z

By:

Bhushan, Ravi;
Agarwal, Charu

Publication type:

Article

X-ray crystallographic and theoretical studies of an anticonvulsant enaminone: methyl 4-(4'-bromophenyl)amino-6-methyl-2-oxocyclohex-3-en-1-oate.

Published in:

2003

By:

Edafiogho, I. O.;
Denny, B. J.;
Schwalbe, C. H.;
Lowe, P. R.

Publication type:

journal article

Comparative Study of Enantioseparation of Racemic Tryptophan by Ultrafiltration Using BSA-Immobilized and BSA-Interpenetrating Network Polysulfone Membranes.

Published in:

Separation Science & Technology, 2010, v. 45, n. 3, p. 346, doi. 10.1080/01496390903423253

By:

Singh, K.;
Bajaj, H. C.;
Ingole, P.;
Bhattacharya, A.

Publication type:

Article

ENZYMATIC PREPARATION OF CHIRAL PHARMACEUTICAL INTERMEDIATES BY LIPASES*.

Published in:

Journal of Liposome Research, 2001, v. 11, n. 4, p. 355, doi. 10.1081/LPR-100108613

By:

Patel, Ramesh N.

Publication type:

Article

Optimization of the Local Crystallization Processes of Preparing Chiral Drugs in Periodic Crystallizers.

Published in:

Crystallography Reports, 2003, v. 48, n. 6, p. 1059, doi. 10.1134/1.1627448

By:

Tolochko, N. K.;
i, I. A.;
Myal’dun, A. Z.;
Kuznetsov, V. A.;
Okhrimenko, T. M.;
P. York, T. M.

Publication type:

Article

Synthesis and Antifungal Activity of β-Hydroxysulfides of 1,3-Dioxepane Series.

Published in:

Journal of Chemistry, 2018, p. 1, doi. 10.1155/2018/3589342

By:

Pavelyev, Roman S.;
Vafina, Rusalia M.;
Balakin, Konstantin V.;
Gnezdilov, Oleg I.;
Dobrynin, Aleksey B.;
Lodochnikova, Olga A.;
Musin, Rashid Z.;
Chmutova, Galina A.;
Lisovskaya, Svetlana A.;
Nikitina, Liliya E.

Publication type:

Article

Novel Bioactive Chiral Poly(amide-imide)s Containing Different Amino Acids Linkages: Studies on Synthesis, Characterization and Biodegradability.

Published in:

Journal of Polymers & the Environment, 2013, v. 21, n. 2, p. 568, doi. 10.1007/s10924-012-0478-6

By:

Mallakpour, Shadpour;
Banihassan, Kazem;
Sabzalian, Mohammad

Publication type:

Article

Escitalopram: a unique mechanism of action.

Published in:

International Journal of Psychiatry in Clinical Practice, 2004, v. 8, p. 11, doi. 10.1080/13651500410005496

By:

Bræstrup, Claus;
Sanchez, Connie

Publication type:

Article

Concentration-dependent enantioselective transport of chiral timolol maleate across hairless mice skin upon using various concentrations of chiral terpene enhancer (D-Limonene).

Published in:

Journal of Excipients & Food Chemicals, 2013, v. 4, n. 4, p. 158

By:

Afouna, Mohsen I.

Publication type:

Article

Development of a Sensitive and Stereoselective HPLC Method for the Analysis of Pindolol in Plasma and Pharmaceutical Products Using a Chiralpak lB Column and Fluorescence Detection.

Published in:

Scientia Pharmaceutica, 2009, v. 77, n. 1, p. 47, doi. 10.3797/scipharm.0809-04

By:

Hefnawy, Mohamed;
Kassem, Mohamed;
Abdine, Haba;
Al-Zoman, Nourah

Publication type:

Article

Tropos Amino Alcohol Mediated Enantioselective Aryl Transfer Reactions to Aromatic Aldehydes.

Published in:

European Journal of Organic Chemistry, 2014, v. 2014, n. 27, p. 5939, doi. 10.1002/ejoc.201402702

By:

Pisani, Laura;
Bochicchio, Carmela;
Superchi, Stefano;
Scafato, Patrizia

Publication type:

Article

Biocatalytic Synthesis of Enantiopure β-Methoxy-β-arylalanine Derivatives.

Published in:

European Journal of Organic Chemistry, 2014, v. 2014, n. 25, p. 5591, doi. 10.1002/ejoc.201402470

By:

Fan, Shiming;
Liu, Shouxin;
Zhang, Hubo;
Liu, Ying;
Yang, Yihuang;
Jin, Longyi

Publication type:

Article

Enantiopure Chiral Concave N-Heterocyclic Carbene Precursors.

Published in:

European Journal of Organic Chemistry, 2013, v. 2013, n. 33, p. 7556, doi. 10.1002/ejoc.201300830

By:

Reimers, Tim;
Haberhauer, Gebhard;
Benkhäuser, Christian;
Schmidtchen, Franz P.;
Lützen, Arne;
Lüning, Ulrich

Publication type:

Article

Electronically Connected [ n]Helicenes: Synthesis and Chiroptical Properties of Enantiomerically Pure ( E)-1,2-Di([6]helicen-2-yl)ethenes.

Published in:

European Journal of Organic Chemistry, 2013, v. 2013, n. 16, p. 3223, doi. 10.1002/ejoc.201300407

By:

Roose, Jesse;
Achermann, Stefan;
Dumele, Oliver;
Diederich, François

Publication type:

Article

Electronically Connected [ n]Helicenes: Synthesis and Chiroptical Properties of Enantiomerically Pure ( E)-1,2-Di([6]helicen-2-yl)ethenes (Eur. J. Org. Chem. 16/2013).

Published in:

European Journal of Organic Chemistry, 2013, v. 2013, n. 16, p. n/a, doi. 10.1002/ejoc.201300407

By:

Roose, Jesse;
Achermann, Stefan;
Dumele, Oliver;
Diederich, François

Publication type:

Article

In vitro analysis of itraconazole cis-diastereoisomers inhibition of nine cytochrome P450 enzymes: stereoselective inhibition of CYP3A.

Published in:

Xenobiotica, 2019, v. 49, n. 1, p. 36, doi. 10.1080/00498254.2018.1425510

By:

Krasulova, Kristyna;
Dvorak, Zdenek;
Anzenbacher, Pavel

Publication type:

Article

Easy Access to 2,5-Anhydro-1,3-O-isopropylidene-D-glucitol.

Published in:

Synthetic Communications, 2010, v. 40, n. 5, p. 744, doi. 10.1080/00397910903013739

By:

Doboszewski, Bogdan;
Siqueira, EdmilsonClarindo de

Publication type:

Article

Synthesis of 5,5'-Disubstituted Bimorpholines.

Published in:

Synthetic Communications, 2010, v. 40, n. 2, p. 266, doi. 10.1080/00397910902964874

By:

Lippur, Kristin;
Elmers, Cindy;
Kailas, Tiiu;
Müürisepp, Aleksander-Mati;
Pehk, Tõnis;
Kanger, Tõnis;
Lopp, Margus

Publication type:

Article

Simple Resolution of Racemic Salicylic Aldehydes Having an Isobornyl Substituent.

Published in:

Synthetic Communications, 2009, v. 39, n. 20, p. 3639, doi. 10.1080/00397910902792648

By:

Buravlev, EvgenyV.;
Chukicheva, IrinaY.;
Kutchin, AleksandrV.

Publication type:

Article

Novel Convenient Synthesis of Rivastigmine.

Published in:

Synthetic Communications, 2009, v. 39, n. 9, p. 1527, doi. 10.1080/00397910802531948

By:

Hu, Meng;
Zhang, Fu-Li;
Xie, Mei-Hua

Publication type:

Article

Improved Process for the Preparation of Tamsulosin Hydrochloride.

Published in:

Synthetic Communications, 2009, v. 39, n. 8, p. 1451, doi. 10.1080/00397910802519216

By:

Reddy, A. Veera;
Bhaskara Rao, S. Udaya;
Narasimha, G. Lakshmi;
Dubey, P. K.

Publication type:

Article

Asymmetric Addition of Diethylzinc to Ketones promoted by Tartaric Acid Derivatives.

Published in:

Synthetic Communications, 2008, v. 38, n. 14, p. 2374, doi. 10.1080/00397910802139304

By:

Hui, Ailing;
Zhang, Jintang;
Wang, Zhiyong

Publication type:

Article

Synthesis and Characterization of the First Pyrrolidine-Based Chiral Ionic Liquids.

Published in:

Synthetic Communications, 2008, v. 38, n. 9, p. 1439, doi. 10.1080/00397910801916140

By:

Raju, C. M. Haricharan;
Dubey, P. K.;
Acharyulu, Palle V. R.

Publication type:

Article

Novel Synthetic Route of (2S)-6-Fluoro-4-oxo-3,4-dihydro-2H-chromene-2-carboxylic Acid.

Published in:

Synthetic Communications, 2007, v. 37, n. 21, p. 3773, doi. 10.1080/00397910701569726

By:

Yuan, Hua‐Jie;
Qian, Shan;
Hai, Li;
Chen, Yao‐Yao;
Wu, Yong

Publication type:

Article

Facile Synthesis and Unusual Methanesulfonylation Reaction of (2R,3R)-1,4-Dimethoxy-1,1,4,4-tetrasubstituted-2,3-butanediols.

Published in:

Synthetic Communications, 2007, v. 37, n. 15, p. 2483, doi. 10.1080/00397910701462153

By:

Srimurugan, Sankareswaran;
Suresh, Paulsamy;
Viswanathan, Balasubramanian;
Varadarajan, ThirukkallamKanthadai

Publication type:

Article

Asymmetric Synthesis of (2S)‐1‐(3,4‐Dihydroxyphenoxy)‐3‐(3,′4′‐Dimethoxyphenoxy) Ethylamino‐2‐propanol hydrochloride (RO363).

Published in:

Synthetic Communications, 2006, v. 36, n. 13, p. 1897, doi. 10.1080/00397910600602651

By:

Narsaiah, AkkiralaVenkat

Publication type:

Article

Asymmetric Induction From Ethyl Lactate in the Reduction of Acetophenone to Phenylethanol.

Published in:

Synthetic Communications, 2006, v. 36, n. 2, p. 175, doi. 10.1080/00397910500334322

By:

Hüttenhain, Stefan H.

Publication type:

Article

Synthesis of Novel L-Proline Derived Macrocyclic Dioxopolyamines of C<sub>2</sub> Symmetry.

Published in:

Synthetic Communications, 2005, v. 35, n. 2, p. 271, doi. 10.1081/SCC-200048458

By:

Yang, Xuemei;
Li, Baohua;
Fu, Enqin

Publication type:

Article

Synthesis of Enantiomerically Pure (+)-(1S,2R,5S,6R)-endo,endo- 2,6-Diaminobicyclo[3.3.1]nonane.

Published in:

Synthetic Communications, 2003, v. 33, n. 9, p. 1595, doi. 10.1081/SCC-120018786

By:

Butkus, Eugenius;
Malinauskienė, Julė;
Orentas, Edvinas;
Žilinskas, Albinas

Publication type:

Article

An Easy and Clean Synthesis of Chiral 3,4-Diaryl-2,5-diazabicyclo[4.4.0]decanes by Reductive Intramolecular Coupling of Chiral Diimines.

Published in:

Synthetic Communications, 2003, v. 33, n. 2, p. 183, doi. 10.1081/SCC-120015698

By:

Hesemann, Peter;
Moreau, Joël J. E.;
Soto, Thierry

Publication type:

Article

SYNTHESIS OF A NEW CHIRAL o-HYDROXYARYLDIAZAPHOSPHONO- DIAMIDE AS LIGAND CATALYSTS FOR ASYMMETRIC SILYLCYANATION OF AROMATIC ALDEHYDES.

Published in:

Synthetic Communications, 2002, v. 32, n. 18, p. 2751, doi. 10.1081/SCC-120006456

By:

Yang, Zhuo-Hong;
Zhou, Zheng-Hong;
Wang, Li-Xin;
Li, Kang-Ying;
Zhou, Qi-Lin;
Tang, Chu-Chi

Publication type:

Article

Signposts to Chiral Drugs.

Published in:

2011

By:

Trinajstić, Nenad

Publication type:

Book Review

Regulatory and Patenting Aspects of Chiral Drugs.

Published in:

Resonance: Journal of Science Education, 2024, v. 29, n. 4, p. 557, doi. 10.1007/s12045-024-0557-8

By:

Ready, Bireddy Srinivasa;
Dubey, Pramod Kumar

Publication type:

Article

Three-steps in one-pot: whole-cell biocatalytic synthesis of enantiopure (+)- and (-)-pinoresinol via kinetic resolution.

Published in:

Microbial Cell Factories, 2016, v. 15, p. 1, doi. 10.1186/s12934-016-0472-0

By:

Ricklefs, Esther;
Girhard, Marco;
Urlacher, Vlada B.

Publication type:

Article

Biosynthesis of chiral 3-hydroxyvalerate from single propionate-unrelated carbon sources in metabolically engineered E. coli.

Published in:

Microbial Cell Factories, 2010, v. 9, p. 96, doi. 10.1186/1475-2859-9-96

By:

Hsien-Chung Tseng;
Harwell, Catey L.;
Martin, Collin H.;
Prather, Kristala L. J.

Publication type:

Article