Works matching DE "CHEMOGENOMICS"

Results: 161

Intracellular Diagnostics: Hunting for the Mode of Action of Redox-Modulating Selenium Compounds in Selected Model Systems.

Published in:

Molecules, 2014, v. 19, n. 8, p. 12258, doi. 10.3390/molecules190812258

By:

Mániková, Dominika;
Medvecová Letavayová, Lucia;
Vlasáková, Danuša;
Košík, Pavol;
Castellucci Estevam, Ethiene;
Jawad Nasim, Muhammad;
Gruhlke, Martin;
Slusarenko, Alan;
Burkholz, Torsten;
Jacob, Claus;
Chovanec, Miroslav

Publication type:

Article

sBWT: memory efficient implementation of the hardware-acceleration-friendly Schindler transform for the fast biological sequence mapping.

Published in:

Bioinformatics, 2016, v. 32, n. 22, p. 3498, doi. 10.1093/bioinformatics/btw419

By:

Chia-Hua Chang;
Min-Te Chou;
Yi-Chung Wu;
Ting-Wei Hong;
Yun-Lung Li;
Chia-Hsiang Yang;
Jui-Hung Hung

Publication type:

Article

Global optimization-based inference of chemogenomic features from drug--target interactions.

Published in:

Bioinformatics, 2015, v. 31, n. 15, p. 2523, doi. 10.1093/bioinformatics/btv181

By:

Songpeng Zu;
Ting Chen;
Shao Li

Publication type:

Article

ChEMBLSpace—a graphical explorer of the chemogenomic space covered by the ChEMBL database.

Published in:

Bioinformatics, 2013, v. 29, n. 4, p. 523, doi. 10.1093/bioinformatics/bts711

By:

Fechner, Nikolas;
Papadatos, George;
Evans, David;
Morphy, John Richard;
Brewerton, Suzanne Clare;
Thorner, David;
Bodkin, Michael

Publication type:

Article

Drug target prediction using adverse event report systems: a pharmacogenomic approach.

Published in:

Bioinformatics, 2012, v. 28, n. 18, p. i611, doi. 10.1093/bioinformatics/bts413

By:

Takarabe, Masataka;
Kotera, Masaaki;
Nishimura, Yosuke;
Goto, Susumu;
Yamanishi, Yoshihiro

Publication type:

Article

Identification of chemogenomic features from drug–target interaction networks using interpretable classifiers.

Published in:

Bioinformatics, 2012, v. 28, n. 18, p. i487, doi. 10.1093/bioinformatics/bts412

By:

Tabei, Yasuo;
Pauwels, Edouard;
Stoven, Véronique;
Takemoto, Kazuhiro;
Yamanishi, Yoshihiro

Publication type:

Article

sc-PDB: a database for identifying variations and multiplicity of ‘druggable’ binding sites in proteins.

Published in:

Bioinformatics, 2011, v. 27, n. 9, p. 1324, doi. 10.1093/bioinformatics/btr120

By:

Meslamani, Jamel;
Rognan, Didier;
Kellenberger, Esther

Publication type:

Article

Whole-genome microarray analyses of Synechococcus– Vibrio interactions.

Published in:

Environmental Microbiology, 2009, v. 11, n. 10, p. 2698, doi. 10.1111/j.1462-2920.2009.01997.x

By:

Tai, Vera;
Paulsen, Ian T.;
Phillippy, Katherine;
Johnson, D. Aaron;
Palenik, Brian

Publication type:

Article

Chemical genomic screening identifies LY294002 as a modulator of glucocorticoid resistance in MLL-rearranged infant ALL.

Published in:

Leukemia (08876924), 2014, v. 28, n. 4, p. 761, doi. 10.1038/leu.2013.245

By:

Spijkers-Hagelstein, J A P;
Pinhanços, S S;
Schneider, P;
Pieters, R;
Stam, R W

Publication type:

Article

Cover Picture: (Mol. Inf. 12/2018).

Published in:: Molecular Informatics, 2018, v. 37, n. 12, p. N.PAG, doi. 10.1002/minf.201881201
Publication type:: Article

Polypharmacological Drug−target Inference for Chemogenomics.

Published in:

Molecular Informatics, 2018, v. 37, n. 9/10, p. 1, doi. 10.1002/minf.201800050

By:

Schneider, Petra;
Schneider, Gisbert

Publication type:

Article

Generative Recurrent Networks for <italic>De Novo</italic> Drug Design.

Published in:

Molecular Informatics, 2018, v. 37, n. 1/2, p. 1, doi. 10.1002/minf.201700111

By:

Gupta, Anvita;
Müller, Alex T.;
Huisman, Berend J. H.;
Fuchs, Jens A.;
Schneider, Petra;
Schneider, Gisbert

Publication type:

Article

Prediction of PARP Inhibition with Proteochemometric Modelling and Conformal Prediction.

Published in:

Molecular Informatics, 2015, v. 34, n. 6/7, p. 357, doi. 10.1002/minf.201400165

By:

Cortés‐Ciriano, Isidro;
Bender, Andreas;
Malliavin, Thérèse

Publication type:

Article

CS-MINER: A Tool for Association Mining in Binding-Database.

Published in:

Molecular Informatics, 2015, v. 34, n. 4, p. 185, doi. 10.1002/minf.201400142

By:

Mani‐Varnosfaderani, Ahmad;
Valadkhani, Abolfazl;
Jalali‐Heravi, Mehdi

Publication type:

Article

Benchmarking a Wide Range of Chemical Descriptors for Drug-Target Interaction Prediction Using a Chemogenomic Approach.

Published in:

Molecular Informatics, 2014, v. 33, n. 11/12, p. 719, doi. 10.1002/minf.201400066

By:

Sawada, Ryusuke;
Kotera, Masaaki;
Yamanishi, Yoshihiro

Publication type:

Article

Constructing a Foundational Platform Driven by Japan's K Supercomputer for Next-Generation Drug Design.

Published in:

Molecular Informatics, 2014, v. 33, n. 11/12, p. 732, doi. 10.1002/minf.201400067

By:

Brown, J. B.;
Nakatsui, Masahiko;
Okuno, Yasushi

Publication type:

Article

Data Mining of Chemogenomics Data Using Bi-Modal PLS Methods and Chemical Interpretation for Molecular Design.

Published in:

Molecular Informatics, 2014, v. 33, n. 11/12, p. 749, doi. 10.1002/minf.201400061

By:

Hasegawa, Kiyoshi;
Funatsu, Kimito

Publication type:

Article

Quality Issues with Public Domain Chemogenomics Data.

Published in:

Molecular Informatics, 2013, v. 32, n. 11/12, p. 898, doi. 10.1002/minf.201300051

By:

Kalliokoski, Tuomo;
Kramer, Christian;
Vulpetti, Anna

Publication type:

Article

Kinase-Kernel Models: Accurate Chemogenomic Method for the Entire Human Kinome.

Published in:

Molecular Informatics, 2013, v. 32, n. 11/12, p. 922, doi. 10.1002/minf.201300091

By:

Tian, Li;
Mukherjee, Prasenjit;
Martin, Eric

Publication type:

Article

Visualization of Activity Landscapes and Chemogenomics Data.

Published in:

Molecular Informatics, 2013, v. 32, n. 11/12, p. 954, doi. 10.1002/minf.201300044

By:

Hu, Ye;
Stumpfe, Dagmar;
Bajorath, Jürgen

Publication type:

Article

Past, Present, and Future of Chemogenomics.

Published in:

Molecular Informatics, 2013, v. 32, n. 11/12, p. 877, doi. 10.1002/minf.201380133

By:

Renner, Steffen

Publication type:

Article

Computational Study of Drugs by Integrating Omics Data with Kernel Methods.

Published in:

Molecular Informatics, 2013, v. 32, n. 11/12, p. 930, doi. 10.1002/minf.201300090

By:

Wang, Yongcui C.;
Deng, Naiyang;
Chen, Shilong;
Wang, Yong

Publication type:

Article

Towards the Next Generation of Computational Chemogenomics Tools.

Published in:

Molecular Informatics, 2013, v. 32, n. 11/12, p. 1029, doi. 10.1002/minf.201300054

By:

Rognan, D.

Publication type:

Article

Visual Analysis of Biological Activity Data with Scaffold Hunter.

Published in:

Molecular Informatics, 2013, v. 32, n. 11/12, p. 964, doi. 10.1002/minf.201300087

By:

Klein, Karsten;
Koch, Oliver;
Kriege, Nils;
Mutzel, Petra;
Schäfer, Till

Publication type:

Article

CompoundProtein Interaction Prediction Within Chemogenomics: Theoretical Concepts, Practical Usage, and Future Directions.

Published in:

Molecular Informatics, 2013, v. 32, n. 11/12, p. 906, doi. 10.1002/minf.201300101

By:

Brown, J. B.;
Niijima, Satoshi;
Okuno, Yasushi

Publication type:

Article

Inferring Chemogenomic Features from Drug-Target Interaction Networks.

Published in:

Molecular Informatics, 2013, v. 32, n. 11/12, p. 991, doi. 10.1002/minf.201300079

By:

Yamanishi, Yoshihiro

Publication type:

Article

Cover Picture: (Mol. Inf. 11-12/2013).

Published in:: Molecular Informatics, 2013, v. 32, n. 11/12, p. 869, doi. 10.1002/minf.201390017
Publication type:: Article

Progress in the Visualization and Mining of Chemical and Target Spaces.

Published in:

Molecular Informatics, 2013, v. 32, n. 11/12, p. 942, doi. 10.1002/minf.201300041

By:

Medina‐Franco, José L.;
Aguayo‐Ortiz, Rodrigo

Publication type:

Article

A Perspective on Computational Chemogenomics.

Published in:

Molecular Informatics, 2013, v. 32, n. 11/12, p. 1025, doi. 10.1002/minf.201300034

By:

Bajorath, Jürgen

Publication type:

Article

Practice and Challenges of Building a Semantic Framework for Chemogenomics Research.

Published in:

Molecular Informatics, 2013, v. 32, n. 11/12, p. 1000, doi. 10.1002/minf.201300078

By:

Chen, Bin;
Wild, David J.

Publication type:

Article

Proteochemometric modelling coupled to in silico target prediction: an integrated approach for the simultaneous prediction of polypharmacology and binding affinity/potency of small molecules.

Published in:

Journal of Cheminformatics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13321-015-0063-9

By:

Paricharak, Shardul;
Cortés-Ciriano, Isidro;
IJzerman, Adriaan P.;
Malliavin, Thérèse E.;
Bender, Andreas

Publication type:

Article

Chemogenomics approaches to rationalising compound action of traditional Chinese and Ayurvedic medicines.

Published in:

2013

By:

Fauzi, Fazlin Mohd;
Koutsoukas, Alexios;
Lowe, Rob;
Joshi, Kalpana;
Fan, Tai-Ping;
Bender, Andreas

Publication type:

Conference Paper/Materials

In silico target prediction: identification of onand off-targets for crop protection agents.

Published in:

2013

By:

Chiddarwar, Rucha K.;
Bender, Andreas;
Rohrer, Sebastian

Publication type:

Conference Paper/Materials

Are phylogenetic trees suitable for chemogenomics analyses of bioactivity data sets: the importance of shared active compounds and choosing a suitable data embedding method, as exemplified on Kinases.

Published in:

Journal of Cheminformatics, 2013, v. 5, n. 1, p. 1, doi. 10.1186/1758-2946-5-49

By:

Paricharak, Shardul;
Klenka, Tom;
Augustin, Martin;
Patel, Umesh A.;
Bender, Andreas

Publication type:

Article

Improving integrative searching of systems chemical biology data using semantic annotation.

Published in:: Journal of Cheminformatics, 2012, v. 4, n. 1, p. 6, doi. 10.1186/1758-2946-4-6
Publication type:: Article

LICSS - a chemical spreadsheet in microsoft excel.

Published in:: Journal of Cheminformatics, 2012, v. 4, n. 1, p. 3, doi. 10.1186/1758-2946-4-3
Publication type:: Article

Correction: In Silico Repositioning-Chemogenomics Strategy Identifies New Drugs with Potential Activity against Multiple Life Stages of Schistosoma mansoni.

Published in:

2015

By:

null, null

Publication type:

Correction Notice

In Silico Repositioning-Chemogenomics Strategy Identifies New Drugs with Potential Activity against Multiple Life Stages of Schistosoma mansoni.

Published in:

PLoS Neglected Tropical Diseases, 2015, v. 9, n. 1, p. 1, doi. 10.1371/journal.pntd.0003435

By:

Neves, Bruno J.;
Braga, Rodolpho C.;
Bezerra, José C. B.;
Cravo, Pedro V. L.;
Andrade, Carolina H.

Publication type:

Article

Controlling microbial contamination during hydrolysis of AFEX-pretreated corn stover and switchgrass: effects on hydrolysate composition, microbial response and fermentation.

Published in:

Biotechnology for Biofuels, 2015, v. 8, p. 1, doi. 10.1186/s13068-015-0356-2

By:

Serate, Jose;
Dan Xie;
Pohlmann, Edward;
Donald Jr., Charles;
Shabani, Mahboubeh;
Hinchman, Li;
Higbee, Alan;
Mcgee, Mick;
La Reau, Alex;
Klinger, Grace E.;
Li, Sheena;
Myers, Chad L.;
Boone, Charles;
Bates, Donna M.;
Cavalier, Dave;
Eilert, Dustin;
Oates, Lawrence G.;
Sanford, Gregg;
Sato, Trey K.;
Dale, Bruce

Publication type:

Article

DNA is structured as a linear 'jigsaw puzzle' in the genomes of Arabidopsis, rice, and budding yeast.

Published in:

Genome, 2014, v. 57, n. 1, p. 9, doi. 10.1139/gen-2013-0099

By:

Liu, Yun-Hua;
Zhang, Meiping;
Wu, Chengcang;
Huang, James J.;
Zhang, Hong-Bin;
Gulick, P.

Publication type:

Article

A chemogenomic approach to understand the antifungal action of Lichen-derived vulpinic acid.

Published in:

Journal of Applied Microbiology, 2016, v. 121, n. 6, p. 1580, doi. 10.1111/jam.13300

By:

Kwon, Y.;
Cha, J.;
Chiang, J.;
Tran, G.;
Giaever, G.;
Nislow, C.;
Hur, J.‐S.;
Kwak, Y.‐S.

Publication type:

Article

Biochemical Diagnosis of Systemic Mast Cell Disorders.

Published in:

Journal of Investigative Dermatology, 1991, v. 96, p. 19, doi. 10.1111/1523-1747.ep12468945

By:

Roberts, L. Jackson;
Oates, John A.

Publication type:

Article

Integration and mining of malaria molecular, functional and pharmacological data: how far are we from a chemogenomic knowledge space?

Published in:

Malaria Journal, 2006, v. 5, p. 1, doi. 10.1186/1475-2875-5-110

By:

Birkholtz, Lyn-Marie;
Bastien, Olivier;
Wells, Gordon;
Grando, Delphine;
Joubert, Fourie;
Kasam, Vinod;
Zimmermann, Marc;
Ortet, Philippe;
Jacq, Nicolas;
Saïdani, Nadia;
Roy, Sylvaine;
Hofmann-Apitius, Martin;
Breton, Vincent;
Louw, Abraham I.;
Maréchal, Eric

Publication type:

Article

Processing of Nonconventional DNA Strand Break Ends.

Published in:

Environmental & Molecular Mutagenesis, 2007, v. 48, n. 9, p. 772, doi. 10.1002/em.20346

By:

Wilson III, David M.

Publication type:

Article

New aspects and strategies for methane mitigation from ruminants.

Published in:

Applied Microbiology & Biotechnology, 2014, v. 98, n. 1, p. 31, doi. 10.1007/s00253-013-5365-0

By:

Kumar, Sanjay;
Choudhury, Prasanta;
Carro, Maria;
Griffith, Gareth;
Dagar, Sumit;
Puniya, Monica;
Calabro, Serena;
Ravella, Sreenivas;
Dhewa, Tejpal;
Upadhyay, Ramesh;
Sirohi, Sunil;
Kundu, Shivlal;
Wanapat, Metha;
Puniya, Anil

Publication type:

Article

Activation of Ah Receptor by Pure Humic Acids.

Published in:

Environmental Toxicology, 2006, v. 21, n. 4, p. 338, doi. 10.1002/tox.20185

By:

Bittner, Michal;
Janošek, Jaroslav;
Hilscherová, Klára;
Giesy, John;
Holoubek, Ivan;
Biáha, Luděk

Publication type:

Article

Teaching About Chemical Rent Gloves With Educational Exhibits.

Published in:

Journal of Family & Consumer Sciences, 2002, v. 94, n. 4, p. 34

By:

Manikowske, Linda;
Stone, Janis;
Farr, Brecca;
Wilson, James;
Wintersteen, Wendy

Publication type:

Article

Chemogenomic profiling of Plasmodium falciparum as a tool to aid antimalarial drug discovery.

Published in:

Scientific Reports, 2015, p. 15930, doi. 10.1038/srep15930

By:

Pradhan, Anupam;
Siwo, Geoffrey H.;
Singh, Naresh;
Martens, Brian;
Balu, Bharath;
Button-Simons, Katrina A.;
Tan, Asako;
Zhang, Min;
Udenze, Kenneth O.;
Jiang, Rays H.Y.;
Ferdig, Michael T.;
Adams, John H.;
Kyle, Dennis E.

Publication type:

Article

Target Identification of Mycobacterium tuberculosis Phenotypic Hits Using a Concerted Chemogenomic, Biophysical, and Structural Approach.

Published in:

Frontiers in Pharmacology, 2017, p. 1, doi. 10.3389/fphar.2017.00681

By:

Mugumbate, Grace;
Mendes, Vitor;
Blaszczyk, Michal;
Sabbah, Mohamad;
Papadatos, George;
Lelievre, Joel;
Ballell, Lluis;
Barros, David;
Abell, Chris;
Blundell, Tom L.;
Overington, John P.

Publication type:

Article

Enhancing Drug Efficacy and Therapeutic Index through Cheminformatics-Based Selection of Small Molecule Binary Weapons That Improve Transporter-Mediated Targeting: A Cytotoxicity System Based on Gemcitabine.

Published in:

Frontiers in Pharmacology, 2017, v. 8, p. 1, doi. 10.3389/fphar.2017.00155

By:

Grixti, Justine M.;
O'hagan, Steve;
Day, Philip J.;
Kell, Douglas B.

Publication type:

Article