Works about CHEMICAL libraries

Results: 777
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    Discovery of Z1362873773: a novel fascin inhibitor from a large chemical library for colorectal cancer.

    Published in:
    Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-96457-x
    By:
    • Rodríguez-Martínez, Alejandro;
    • Giraldo-Ruiz, Lucía;
    • Ramos, María C.;
    • Luque, Irene;
    • Ribeiro, Diogo;
    • Postigo-Corrales, Fátima;
    • Alburquerque-González, Begoña;
    • Montoro-García, Silvia;
    • Arroyo-Rodríguez, Ana Belén;
    • Conesa-Zamora, Pablo;
    • Hurtado, Ana María;
    • Luengo-Gil, Ginés;
    • Pérez-Sánchez, Horacio
    Publication type:
    Article
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    Inflammatory signaling pathways play a role in SYK inhibitor resistant AML.

    Published in:
    Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-96660-w
    By:
    • Tausch, Sarah;
    • Villinger, Christina;
    • Alexe, Gabriela;
    • Urban, Daniel J.;
    • Shen, Min;
    • Jahn, Dominique;
    • Vischedyk, Jonas;
    • Scheich, Sebastian;
    • Serve, Hubert;
    • Hall, Matthew D.;
    • Stegmaier, Kimberly;
    • Oellerich, Thomas;
    • Cremer, Anjali
    Publication type:
    Article
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    Identification of new ClpC1-NTD binders for Mycobacterium tuberculosis drug development.

    Published in:
    Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-92778-z
    By:
    • Weinhäupl, Katharina;
    • Meuret, Louis;
    • Desrat, Sandy;
    • Roussi, Fanny;
    • Morellet, Nelly;
    • Beaupierre, Sandra;
    • Guillou, Catherine;
    • van Heijenoort, Carine;
    • Abian, Olga;
    • Vega, Sonia;
    • Wolf, Ian;
    • Akopian, Tatos;
    • Krandor, Olga;
    • Rubin, Eric;
    • Velazquez-Campoy, Adrian;
    • Gauto, Diego;
    • Fraga, Hugo
    Publication type:
    Article
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    Identification of new ClpC1-NTD binders for Mycobacterium tuberculosis drug development.

    Published in:
    Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-87535-1
    By:
    • Weinhäupl, Katharina;
    • Meuret, Louis;
    • Desrat, Sandy;
    • Roussy, Fanny;
    • Morellet, Nelly;
    • Beaupierre, Sandra;
    • Guillou, Catherine;
    • van Heijenoort, Carine;
    • Abian, Olga;
    • Vega, Sonia;
    • Wolf, Ian;
    • Akopian, Tatos;
    • Krandor, Olga;
    • Rubin, Eric;
    • Velazquez-Campoy, Adrian;
    • Gauto, Diego;
    • Fraga, Hugo
    Publication type:
    Article
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    Virtual fragment screening for DNA repair inhibitors in vast chemical space.

    Published in:
    Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-56893-9
    By:
    • Luttens, Andreas;
    • Vo, Duc Duy;
    • Scaletti, Emma R.;
    • Wiita, Elisée;
    • Almlöf, Ingrid;
    • Wallner, Olov;
    • Davies, Jonathan;
    • Košenina, Sara;
    • Meng, Liuzhen;
    • Long, Maeve;
    • Mortusewicz, Oliver;
    • Masuyer, Geoffrey;
    • Ballante, Flavio;
    • Michel, Maurice;
    • Homan, Evert;
    • Scobie, Martin;
    • Kalderén, Christina;
    • Warpman Berglund, Ulrika;
    • Tarnovskiy, Andrii V.;
    • Radchenko, Dmytro S.
    Publication type:
    Article
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    High-throughput sensitive screening of small molecule modulators of microexon alternative splicing using dual Nano and Firefly luciferase reporters.

    Published in:
    Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-50399-6
    By:
    • Best, Andrew J.;
    • Braunschweig, Ulrich;
    • Wu, Mingkun;
    • Farhangmehr, Shaghayegh;
    • Pasculescu, Adrian;
    • Lim, Justin J.;
    • Comsa, Lim Caden;
    • Jen, Mark;
    • Wang, Jenny;
    • Datti, Alessandro;
    • Wrana, Jeffrey L.;
    • Cordes, Sabine P.;
    • Al-awar, Rima;
    • Han, Hong;
    • Blencowe, Benjamin J.
    Publication type:
    Article
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    Updating and profiling the natural product‐likeness of Latin American compound libraries.

    Published in:
    Molecular Informatics, 2024, v. 43, n. 7, p. 1, doi. 10.1002/minf.202400052
    By:
    • Gómez‐García, Alejandro;
    • Prinz, Ann‐Kathrin;
    • Jiménez, Daniel A. Acuña;
    • Zamora, William J.;
    • Barazorda‐Ccahuana, Haruna L.;
    • Chávez‐Fumagalli, Miguel Á.;
    • Valli, Marilia;
    • Andricopulo, Adriano D.;
    • da S. Bolzani, Vanderlan;
    • Olmedo, Dionisio A.;
    • Solís, Pablo N.;
    • Núñez, Marvin J.;
    • Rodríguez Pérez, Johny R.;
    • Sánchez, Hoover A. Valencia;
    • Cortés Hernández, Héctor F.;
    • Mosquera Martinez, Oscar M.;
    • Koch, Oliver;
    • Medina‐Franco, José L.
    Publication type:
    Article
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