Works about CHEMICAL inhibitors

Results: 5000

Crinecerfont.

Published in:: American Journal of Health-System Pharmacy, 2025, v. 82, n. 10, p. 505, doi. 10.1093/ajhp/zxaf017
Publication type:: Article

The progress and prospects of targeting the adenosine pathway in cancer immunotherapy.

Published in:

Biomarker Research, 2025, v. 13, n. 1, p. 1, doi. 10.1186/s40364-025-00784-0

By:

Yang, Yuying;
Zhu, Lin;
Xu, Yantao;
Liang, Long;
Liu, Li;
Chen, Xiang;
Li, Hui;
Liu, Hong

Publication type:

Article

Biaryl Phosphates and Phosphonates as Selective Inhibitors of the Transcription Factor STAT4.

Published in:

Angewandte Chemie, 2025, v. 137, n. 21, p. 1, doi. 10.1002/ange.202504420

By:

Brovchenko, Nadiya;
Berg, Angela;
Schubert, Sabine;
Gräb, Julian;
Münzel, Theresa;
Protzel, Christoph;
Natarajan, Kalaiselvi;
Berg, Thorsten

Publication type:

Article

Update on the Management of Cholestatic Pruritus.

Published in:

Gastroenterology & Hepatology, 2025, v. 21, p. 315

By:

Brown, Kimberly

Publication type:

Article

Development of Efficient Covalent Inactivators of a Fungal Aspartate Semialdehyde Dehydrogenase.

Published in:

Drug Development Research, 2025, v. 86, n. 3, p. 1, doi. 10.1002/ddr.70095

By:

Friday, Samantha N.;
Koellner, Liezel A.;
Brown, Spencer W.;
Calbat, Christopher N.;
Curran, Catherine F.;
Dietz, Jordan D.;
Koenig‐Dummer, Andreas;
Friday, Paul D.;
Parker, James A.;
Simmons, Noah A.;
Urmey, Finnean A.;
West, Alexis N.;
Zagler, Sebastian G.;
Viola, Ronald E.;
Halkides, Christopher J.

Publication type:

Article

Identification and Characterization of Highly Potent and Isoenzyme-Selective Inhibitors of Deiodinase Type I via a Nonradioactive High-Throughput Screening Method.

Published in:

Thyroid, 2025, v. 35, n. 5, p. 576, doi. 10.1089/thy.2025.0036

By:

Sane, Rajas;
Seyffarth, Carola;
Kleissle, Sabrina;
Neuenschwander, Martin;
von Kries, Jens Peter;
Frädrich, Caroline;
Renko, Kostja;
Wirth, Eva K.;
Köhrle, Josef

Publication type:

Article

Effectiveness of 4-Factor Prothrombin Complex Concentrate with and without Vitamin K in Managing Warfarin-Associated Major Bleeding.

Published in:

Eurasian Journal of Medicine, 2025, v. 57, n. 1, p. 1, doi. 10.5152/eurasianjmed.2025.25710

By:

Temür, Şeyma Arzu;
Ayar, Mustafa Selçuk;
Kurnaz, Yiğit;
Çalışkan, Fatih

Publication type:

Article

Next-Generation Anti-IL-17 Agents for Psoriatic Disease: A Pipeline Review.

Published in:

American Journal of Clinical Dermatology, 2025, v. 26, n. 3, p. 307, doi. 10.1007/s40257-025-00928-w

By:

Kim, Dahyeon;
Yang, Seanna;
Gill, Minka;
Babaei, Nickoulet;
Cervantes, Mireya;
Wu, Jashin J.

Publication type:

Article

Colorimetric determination of tyrosinase activity and high-throughput screening of inhibitors based on in-situ formation of gold nanoparticles.

Published in:

Microchimica Acta, 2025, v. 192, n. 5, p. 1, doi. 10.1007/s00604-025-07155-4

By:

Zhou, Guohua;
Liu, Zhicheng;
Huang, Yuning;
Yang, Rufei;
Guo, Xin;
Jia, Yongmei;
Liu, Peilian;
Li, Zhiguo;
Cui, Wenjuan

Publication type:

Article

二氢猕猴桃内酯抑制胃癌细胞增殖的作用机制研究.

Published in:

Practical Oncology Journal, 2025, v. 39, n. 2, p. 91, doi. 10.11904/j.issn.1002-3070.2025.02.004

By:

陈丽娟;
马欣欣;
高光强;
田虹;
刘家仁

Publication type:

Article

Voritoxetine induced generalised pruritus: A preventable incident.

Published in:

2025

By:

Roy, Ayesmita;
Chatterjee, Sambit;
Das, Anupam

Publication type:

Letter

Exploring the potential of Gonolobus condurango as a histone deacetylase inhibitor in triple-negative breast cancer cell lines: in vitro study.

Published in:

BMC Complementary Medicine & Therapies, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12906-025-04896-w

By:

Vajen, Beate;
Schäffer, Vera;
Eilers, Marlies;
Schlegelberger, Brigitte;
Skawran, Britta

Publication type:

Article

Astrocytic spermidine insufficiency contributes to enhanced pain sensitivity associated with ApoE4.

Published in:

Journal of Headache & Pain, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s10194-025-02054-8

By:

Yu, Kaiming;
Zhou, Xiongyao;
Li, Baolong;
Sun, Jialu;
Yang, Tuo;
Li, Weizhen;
Wang, Ningning;
Gu, Xiaosong;
Cui, Shusen;
Cao, Rangjuan

Publication type:

Article

Reply to correspondence.

Published in:

2025

By:

Ismail, Omar;
Albdour, Karam;
Jaber, Yazan;
Jaber, Kamel;
Alsaras, Ameen

Publication type:

Letter

CDK4/6 Inhibitors-Induced Macrocytosis Is Not Associated with Hemolysis and Does Not Impact Hemoglobin Homeostasis.

Published in:

Cancers, 2025, v. 17, n. 9, p. 1567, doi. 10.3390/cancers17091567

By:

Barroso, Tiago;
Costa, Leila;
Gonçalves, Lisa;
Patel, Vanessa;
Araújo, João;
Pinho, Inês;
Monteiro, Carolina;
Esperança-Martins, Miguel;
Abreu, Catarina;
de Sousa, Rita Teixeira;
Pais, Helena;
Nogueira-Costa, Gonçalo;
Torres, Sofia;
Ribeiro, Leonor Abreu;
da Costa, Luís Marques

Publication type:

Article

Mechanistic Roles of Transcriptional Cyclin-Dependent Kinases in Oncogenesis: Implications for Cancer Therapy.

Published in:

Cancers, 2025, v. 17, n. 9, p. 1554, doi. 10.3390/cancers17091554

By:

Alrouji, Mohammed;
Alshammari, Mohammed S.;
Anwar, Saleha;
Venkatesan, Kumar;
Shamsi, Anas

Publication type:

Article

Safely Targeting Cancer, the Wound That Never Heals, Utilizing CBP/Beta-Catenin Antagonists.

Published in:

Cancers, 2025, v. 17, n. 9, p. 1503, doi. 10.3390/cancers17091503

By:

Higuchi, Yusuke;
Teo, Jia-Ling;
Yi, Daniel;
Kahn, Michael

Publication type:

Article

Current Treatment of Uveal Melanoma.

Published in:

Cancers, 2025, v. 17, n. 9, p. 1403, doi. 10.3390/cancers17091403

By:

Hanratty, Katie;
Finegan, Gráinne;
Rochfort, Keith D.;
Kennedy, Susan

Publication type:

Article

Pembrolizumab-induced donor duodenum perforation after remote simultaneous pancreas-kidney transplant: a case report and literature review.

Published in:

Renal Replacement Therapy, 2025, v. 11, n. 1, p. 1, doi. 10.1186/s41100-025-00626-7

By:

Shirini, Kasra;
Drachenberg, Cinthia;
Meier, Raphael P. H.

Publication type:

Article

Myriocin Restores Metabolic Homeostasis in dAGE-Exposed Mice via AMPK-PGC1α-Mediated Mitochondrial Activation and Systemic Lipid/Glucose Regulation.

Published in:

Nutrients, 2025, v. 17, n. 9, p. 1549, doi. 10.3390/nu17091549

By:

He, Libo;
Dang, Jinye;
Li, Jingjing;
Xue, Hairui;
Cai, Jiaxiu;
Cheng, Guohua;
Yang, Yuhui;
Liu, Zhiyi;
Liu, Binghua;
Dai, Yali;
Zhang, Yu;
Huang, Yating;
Sun, Yiran;
Guo, Jinlin;
Liu, Ke

Publication type:

Article

A novel approach for evaluating transthyretin kinetic stabilizers using plasma samples.

Published in:

2025

By:

Costa-Rodrigues, Diogo;
Saraiva, Maria João;
Almeida, Maria Rosário;
Gales, Luís

Publication type:

Letter to the Editor

Taurine corrects lupus CD4<sup>+</sup> T cell imbalance through inhibition of mTORC1 signaling.

Published in:

Nutrition & Metabolism, 2025, v. 22, n. 1, p. 1, doi. 10.1186/s12986-025-00936-x

By:

Huang, Saisai;
Cui, Yiyuan;
Zhang, Yaqi;
Deng, Hanyin;
Liu, Shanshan;
Feng, Xuebing

Publication type:

Article

Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors for Anemia in Non-Dialysis Dependent Chronic Kidney Disease: Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Published in:

Indian Journal of Nephrology, 2025, v. 35, n. 2, p. 1, doi. 10.25259/ijn_382_23

By:

Tyagi, Jyoti;
Kaur, Manveen;
Moola, Sandeep;
Ramachandran, Raja;
Meena, Priti;
Bajpai, Divya;
Bhaumik, Soumyadeep

Publication type:

Article

Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors for Anemia in Dialysis-Dependent Chronic Kidney Disease: Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Published in:

Indian Journal of Nephrology, 2025, v. 35, n. 2, p. 1, doi. 10.25259/ijn_379_23

By:

Tyagi, Jyoti;
Kaur, Manveen;
Ingale, Samiksha;
Ramachandran, Raja;
Meena, Priti;
Bajpai, Divya;
Bhaumik, Soumyadeep

Publication type:

Article

CEG-0598, a novel dual inhibitor of EGFR and C5aR demonstrates in vitro anticancer and antimetastatic activity in prostate cancer cells.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02574-4

By:

Dera, Ayed A.;
Al Fayi, Majed

Publication type:

Article

Exploring the Molecular Impact of Achillea arabica on Hepatocellular Carcinoma: A Computational Study.

Published in:

Journal of Computational Biophysics & Chemistry, 2025, v. 24, n. 7, p. 909, doi. 10.1142/S2737416525500024

By:

Akkaya, Hatice;
Özmaldar, Aydın

Publication type:

Article

Evaluation of Safety, Pharmacokinetic, and Pharmacodynamic Characteristics of a Novel Dual mGluR5/5-HT2AR Antagonist (VVZ-2471) in a Randomized, Double-Blind, First-in-Human Study.

Published in:

CNS Drugs, 2025, v. 39, n. 6, p. 583, doi. 10.1007/s40263-025-01181-9

By:

Bae, Sungyeun;
Lee, HyunJoon;
Song, Inkyung;
Kim, Jina;
Lee, Sang Rim;
Cho, Sunyoung;
Yu, Kyung-Sang;
Chung, Jae-Yong

Publication type:

Article

Safety, efficacy, and compliance of moderate-to-high dose eptinezumab and erenumab in chronic migraine patients with medication-overuse headache: an updated systematic review and meta-analysis.

Published in:

Journal of Headache & Pain, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s10194-025-02047-7

By:

Nguyen, Nhan;
Ho Quang Tri, Vinh;
Nguyen Ngoc Dan, Vy;
Bao Tran, Nghi;
Olah, Laszlo;
Heja, Mate

Publication type:

Article

LIBX‐A401: A Novel Selective Inhibitor of Acyl‐CoA Synthetase Long Chain Family Member 4 (ACSL4) and Its Binding Mode.

Published in:

Angewandte Chemie, 2025, v. 137, n. 19, p. 1, doi. 10.1002/ange.202500518

By:

Mazhari Dorooee, Darius;
Ravez, Séverine;
Vertommen, Didier;
Renault, Nicolas;
Papadopoulos, Nicolas;
Marteau, Romain;
Charnelle, Emeline;
Porte, Karine;
Gobert, Alexandre;
Hennuyer, Nathalie;
Herinckx, Gaetan;
Pautric, Maëla;
Jonneaux, Aurélie;
Devedjian, Jean Christophe;
Devos, David;
Staels, Bart;
Melnyk, Patricia;
Constantinescu, Stefan N.;
Frédérick, Raphaël;
El Bakali, Jamal

Publication type:

Article

Compound FLZ attenuates neuroinflammation through inhibiting Src/PTEN/Akt signaling pathway.

Published in:

Journal of Asian Natural Products Research, 2025, v. 27, n. 5, p. 770, doi. 10.1080/10286020.2024.2435981

By:

Li, Fang-Fang;
Zheng, Yuan-Peng;
Li, Gen;
Yang, Yang;
Ma, Jing-Wei;
Zang, Cai-Xia;
Tao, Deng;
Li, Li;
Bao, Xiu-Qi;
Zhang, Dan

Publication type:

Article

Obacunone acts as a histone deacetylase 1 inhibitor to limit p38MAPK signaling and alleviate osteoarthritis progression.

Published in:

Journal of Orthopaedic Surgery & Research, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13018-025-05804-1

By:

Gao, Yong;
Wang, Ke;
Shi, Chao;
Gao, Yang;
Kong, De-Qian

Publication type:

Article

Direct oral anticoagulants versus conventional anticoagulants for deep vein thrombosis.

Published in:

Academic Emergency Medicine, 2023, v. 30, n. 9, p. 974, doi. 10.1111/acem.14763

By:

Long, Brit;
Gottlieb, Michael

Publication type:

Article

Importance of Fruits and Vegetables in Cancer Prevention.

Published in:

Nutritional Perspectives: Journal of the Council on Nutrition, 2006, v. 29, n. 3, p. 37

By:

Pham, Susan H.

Publication type:

Article

Antioxidant, mutagenic, and antimutagenic activities of Tragopogon longirostis var. longirostis, an edible wild plant in Turkey.

Published in:

Indian Journal of Pharmacology, 2015, v. 47, n. 4, p. 414, doi. 10.4103/0253-7613.161267

By:

Sarac, Nurdan

Publication type:

Article

A retrospective study of the effects of angiotensin receptor blockers and angiotensin converting enzyme inhibitors in diabetic nephropathy.

Published in:

Indian Journal of Pharmacology, 2015, v. 47, n. 2, p. 148, doi. 10.4103/0253-7613.153420

By:

Pathak, Jahnavi V.;
Dass, Ervilla E.

Publication type:

Article

A low dose of doxorubicin improves antioxidant defence system and modulates anaerobic metabolism during the development of lymphoma.

Published in:

Indian Journal of Pharmacology, 2012, v. 44, n. 3, p. 308, doi. 10.4103/0253-7613.96299

By:

Verma, Nibha;
Vinayak, Manjula

Publication type:

Article

Antioxidant potential of the methanol—methylene chloride extract of Terminalia glaucescens leaves on mice liver in streptozotocin-induced stress.

Published in:

Indian Journal of Pharmacology, 2008, v. 40, n. 6, p. 266

By:

Njomen, Guy Bertrand Sabas Nya;
Kamgang, René;
Oyono1, Jean Louis Essame;
Njikam, Njifutie

Publication type:

Article

Pharmacoinformatics.

Published in:: 2008
Publication type:: Abstract

In vitro antioxidant activity of pet ether extract of black pepper.

Published in:

Indian Journal of Pharmacology, 2008, v. 40, n. 4, p. 147, doi. 10.4103/0253-7613.43160

By:

Singh, Ramnik;
Singh, Narinder;
Saini, B. S.;
Rao, Harwinder Singh

Publication type:

Article

Free radical scavenging activity of gossypin and nevadensin: An in-vitro evaluation.

Published in:

Indian Journal of Pharmacology, 2007, v. 39, n. 6, p. 281, doi. 10.4103/0253-7613.39147

By:

Ganapaty, S.;
Chandrashekhar, V. M.;
Chitme, H. R.;
Narsu, M. Lakashmi

Publication type:

Article

Antioxidant activity of ethyl acetate soluble fraction of Acacia arabica bark in rats.

Published in:

Indian Journal of Pharmacology, 2007, v. 39, n. 1, p. 33

By:

Sundaram, R.;
Mitra, S. K.

Publication type:

Article

In vivo antioxidant activity of hydroalcoholic extract of Taraxacum araxacum officinale roots in rats.

Published in:

Indian Journal of Pharmacology, 2006, v. 38, n. 1, p. 54, doi. 10.4103/0253-7613.19854

By:

Sumanth, Meera;
Rana, A. C.

Publication type:

Article

Pharmacological investigation of prunin-6"-O-p-coumarate: A flavonoid glycoside.

Published in:

Indian Journal of Pharmacology, 2004, v. 36, n. 4, p. 244

By:

Harikrishna, D.;
Rao, A. V. N Appa;
Prabhakar, M. C.

Publication type:

Article

Comparison of inhibitory effect of ATP-dependent K <sup> + </sup> channel blockers glibenclamide and chlorpropamide, on diazoxide-induced relaxation of rat ileum.

Published in:

Indian Journal of Pharmacology, 2004, v. 36, n. 2, p. 84

By:

Babaei, A.;
Mohiti, J.

Publication type:

Article

Oxidative stress and antioxidant status in acute organophosphorous insecticide poisoning.

Published in:

Indian Journal of Pharmacology, 2004, v. 36, n. 2, p. 76

By:

Vidyasagar, J.;
Karunakar, N.;
Reddy, M.S.;
Rajnarayana, K.;
Surender, T.;
Krishna, D.R.

Publication type:

Article

Echinocandins: A promising new antifungal group.

Published in:

Indian Journal of Pharmacology, 2004, v. 36, n. 2, p. 65

By:

Randhawa, G.K.;
Sharma, G.

Publication type:

Article

Uptake of Antioxidants by Natural Nutrition and Supplementation: Pros and Cons from the Dermatological Point of View.

Published in:

Skin Pharmacology & Physiology, 2011, v. 24, n. 5, p. 269, doi. 10.1159/000328725

By:

Lademann, J.;
Patzelt, A.;
Schanzer, S.;
Richter, H.;
Meinke, M.C.;
Sterry, W.;
Zastrow, L.;
Doucet, O.;
Vergou, T.;
Darvin, M.E.

Publication type:

Article

Inhibitor of the Tyrosine Phosphatase STEP Reverses Cognitive Deficits in a Mouse Model of Alzheimer's Disease.

Published in:

PLoS Biology, 2014, v. 12, n. 8, p. 1, doi. 10.1371/journal.pbio.1001923

By:

Xu, Jian;
Chatterjee, Manavi;
Baguley, Tyler D.;
Brouillette, Jonathan;
Kurup, Pradeep;
Ghosh, Debolina;
Kanyo, Jean;
Zhang, Yang;
Seyb, Kathleen;
Ononenyi, Chimezie;
Foscue, Ethan;
Anderson, George M.;
Gresack, Jodi;
Cuny, Gregory D.;
Glicksman, Marcie A.;
Greengard, Paul;
Lam, TuKiet T.;
Tautz, Lutz;
Nairn, Angus C.;
Ellman, Jonathan A.

Publication type:

Article

An Enzymatic Atavist Revealed in Dual Pathways for Water Activation.

Published in:

PLoS Biology, 2008, v. 6, n. 8, p. e206, doi. 10.1371/journal.pbio.0060206

By:

Min, Donghong;
Josephine, Helen R.;
Li, Hongzhi;
Lakner, Clemens;
MacPherson, Iain S.;
Naylor, Gavin J. P.;
Swofford, David;
Hedstrom, Lizbeth;
Yang, Wei

Publication type:

Article

Gene Expression Analysis of Zebrafish Heart Regeneration.

Published in:

PLoS Biology, 2006, v. 4, n. 8, p. e260, doi. 10.1371/journal.pbio.0040260

By:

Ching-Ling Lien;
Schebesta, Michael;
Makino, Shinji;
Weber, Gerhard J.;
Keating, Mark T.

Publication type:

Article