Works matching DE "CHEMICAL inhibitors"

Results: 5000

Mirdametinib: First Approval.

Published in:

Drugs, 2025, v. 85, n. 7, p. 977, doi. 10.1007/s40265-025-02190-0

By:

Hoy, Sheridan M.

Publication type:

Article

Kick-starting the cancer-immunity cycle by targeting CD40.

Published in:

OncoImmunology, 2015, v. 4, n. 7, p. N.PAG, doi. 10.1080/2162402X.2015.1011484

By:

Ellmark, P;
Mangsbo, S M;
Furebring, C;
Tötterman, T H;
Norlén, P

Publication type:

Article

A novel combinatorial cancer immunotherapy.

Published in:

OncoImmunology, 2014, v. 3, n. 5, p. N.PAG, doi. 10.4161/onci.28440

By:

Nagato, Toshihiro;
Celis, Esteban

Publication type:

Article

Studying the role of the immune system on the antitumor activity of a Hedgehog inhibitor against murine osteosarcoma.

Published in:

OncoImmunology, 2012, v. 1, n. 8, p. 1313, doi. 10.4161/onci.21680

By:

Paget, Christophe;
Duret, Helene;
Ngiow, Shin Foong;
Kansara, Maya;
Thomas, David M.;
Smyth, Mark J.

Publication type:

Article

Diagnosis, management, and outcomes of immune checkpoint inhibitor induced acute interstitial nephritis: A single-center experience.

Published in:

Journal of Oncology Pharmacy Practice, 2025, v. 31, n. 4, p. 641, doi. 10.1177/10781552241252627

By:

Elghawy, Omar;
Patel, Reema;
Barsouk, Adam;
Puthumana, Joe;
Xu, Jason;
Sussman, Jonathan;
Horton, Bethany;
Kaur, Varinder

Publication type:

Article

Effects of Geldanamycin and Other Naturally Occurring Small Molecule Antagonists of Heat Shock Protein 90 on HER2 Protein Expression.

Published in:

Breast Disease, 1999, v. 11, n. 1, p. 49

By:

Neckers, Len

Publication type:

Article

The Potential of Tyrphostins for the Therapy of Breast Cancer.

Published in:

Breast Disease, 1999, v. 11, n. 1, p. 145

By:

Levitzki, Alexander;
Gazit, Aviv

Publication type:

Article

Physicochemical properties and biological efficacy of 30 DYRK2 Inhibitors for the treatment of prostate cancer.

Published in:

Vietnam Journal of Chemistry, 2024, v. 62, n. 5, p. 624, doi. 10.1002/vjch.202300313

By:

Joshi, Sravani;
Srivastava, Ruby

Publication type:

Article

Surface modification of natural porous silica microparticles to control the loading and release of organic corrosion inhibitors in coatings.

Published in:

NPG Asia Materials, 2025, v. 17, n. 1, p. 1, doi. 10.1038/s41427-025-00608-5

By:

Zhao, Jingjing;
Na, Dong-Hyuk;
Garcia, Santiago J.

Publication type:

Article

NADPH oxidase-2 inhibitor apocynin attenuates high-fat diet-induced kidney and bladder injury.

Published in:

Marmara Medical Journal, 2025, v. 38, n. 2, p. 171, doi. 10.5472/marumj.1706664

By:

KANPALTA MUSTAFAOGLU, Fatma;
ERTAS, Busra;
SENER, Goksel;
ERCAN, Feriha

Publication type:

Article

Clinical and Economic Burden of Patients With Haemophilia A and B in France: Analysis of a Nationwide Claims Database.

Published in:

Haemophilia, 2025, v. 31, n. 3, p. 424, doi. 10.1111/hae.70041

By:

Frenzel, Laurent;
Bouée, Stéphane;
Lilliu, Hervé;
Cahoreau, Véronique;
Giraud, Nicolas;
Delienne, Stéphanie;
Fagnani, Francis;
Cottin, Juliette;
Bureau, Isabelle;
Reynaud, Anaïs;
Fahfouhi, Yasmine;
Coumert, Amélie;
Beillat, Maud;
Mammar, Nadir;
Rudant, Jérémie;
Lebreton, Aurélien

Publication type:

Article

Trends in Treatment of Severe Haemophilia and Impact on Inhibitor Assessment by the EUHASS Registry.

Published in:

Haemophilia, 2025, v. 31, n. 3, p. 433, doi. 10.1111/hae.70039

By:

Fischer, Kathelijn;
Lassila, Riitta;
Peyvandi, Flora;
Gatt, Alex;
Gouw, Samantha C.;
Hollingsworth, Rob;
Lambert, Thierry;
Kaczmarek, Radoslaw;
Carbonero, Diana;
Makris, Michael

Publication type:

Article

Blood Group O Does Not Increase the Risk of Inhibitors in Severe Haemophilia A: Data from the PedNet Study Group.

Published in:

Haemophilia, 2025, v. 31, n. 3, p. 419, doi. 10.1111/hae.70035

By:

de Kovel, Marloes;
van Haaster, Aimée‐Claire;
Carcao, Manuel;
Ranta, Susanna;
Glosli, Heidi;
Rivard, Georges E.;
Kenet, Gili;
Kurnik, Karin;
Van Geet, Christel;
Carvalho, Manuela;
Andersson, Nadine G.;
Kartal‐Kaess, Mutlu;
Ljung, Rolf;
van den Berg, H. Marijke

Publication type:

Article

Inhibitor Eradication in Postpartum Acquired Haemophilia A: Real‐Life Case Series and Literature Review.

Published in:

Haemophilia, 2025, v. 31, n. 3, p. 494, doi. 10.1111/hae.70020

By:

Giuffrida, Gaetano;
Markovic, Uros;
Grasso, Stephanie;
Duminuco, Andrea;
Santuccio, Gabriella;
Fazio, Manlio;
Giunta, Giuliana;
Gullo, Lara;
Sorbello, Chiara;
Frazzetto, Sara;
La Penta, Salvatore;
Napolitano, Mariasanta;
Sottilotta, Gianluca;
Di Raimondo, Francesco;
Sapuppo, Gabriele

Publication type:

Article

β‐Glucuronidase Inhibition in Drug Development: Emerging Strategies for Mitigating Drug‐Induced Toxicity and Enhancing Therapeutic Outcomes.

Published in:

Drug Development Research, 2025, v. 86, n. 4, p. 1, doi. 10.1002/ddr.70118

By:

Allam, Ahmed A.;
Rudayni, Hassan A.;
Ahmed, Noha A.;
Alkhayl, Faris F. Aba;
Lamsabhi, Al Mokhtar;
Kamel, Emadeldin M.

Publication type:

Article

Clinical Investigation of Tyrosinase Inhibitors: Past, Present, and Future.

Published in:

Drug Development Research, 2025, v. 86, n. 4, p. 1, doi. 10.1002/ddr.70113

By:

Wang, Yuanyuan;
Jiang, Ruijia;
Xiong, Baichen;
Zhu, Jiawei;
Sang, Jingjing;
Li, Hongtao;
Chen, Chen;
Xu, Ziwei;
Zhang, Weiting;
Chen, Yao;
Feng, Feng;
Sun, Haopeng

Publication type:

Article

Exploring 2‐Thioxo‐1,2,3,4‐tetrahydropyrimidines as Dual Acting GSK‐3β/Aβ Aggregation Inhibitors: Implications for Alzheimer's Disease Treatment.

Published in:

Drug Development Research, 2025, v. 86, n. 4, p. 1, doi. 10.1002/ddr.70112

By:

Sukanya, Sukanya;
Bellver‐Sanchis, Aina;
Choudhary, Bhanwar Singh;
Kumar, Sunil;
Pérez, Belén;
Rodríguez, Antón Leandro Martínez;
Brea, Jose;
Escolano, Carmen;
Griñán‐Ferré, Christian;
Malik, Ruchi

Publication type:

Article

Advanced Strategies to Accumulate Nitrite in Low-feed Concentrated Biological Reactors.

Published in:

Water, Air & Soil Pollution, 2025, v. 236, n. 7, p. 1, doi. 10.1007/s11270-025-08099-4

By:

Keerio, Hareef Ahmed;
Panhwar, Sallahuddin;
Nawab, Said;
Rahman, Mujeeb Ur;
Shah, Syed Bilal;
Suboktagin, Sultan;
Ali, Amjad

Publication type:

Article

The Efficacy of Anti-amyloid Monoclonal Antibodies in Early Alzheimer's Dementia: A Systematic Review.

Published in:

Annals of Indian Academy of Neurology, 2025, v. 28, n. 3, p. 333, doi. 10.4103/aian.aian_547_24

By:

Mostafa, Alyaa;
Tiu, Stephanie;
Khan, Farooq;
Baig, Nusrath A

Publication type:

Article

KDIGO 2024 clinical practice guideline on evaluation and management of chronic kidney disease: A primer on what pharmacists need to know Open Access.

Published in:

American Journal of Health-System Pharmacy, 2025, v. 82, n. 12, p. 660, doi. 10.1093/ajhp/zxaf044

By:

Awdishu, Linda;
Maxson, Rebecca;
Gratt, Chelsea;
Rubenzik, Tamara;
Battistella, Marisa

Publication type:

Article

Concomitant Use of Proton Pump Inhibitors and CDK4/6 Inhibitors in Metastatic Hormone-Positive Breast Cancer: A Real-World Cohort Study.

Published in:

Oncology, 2025, v. 103, n. 6, p. 498, doi. 10.1159/000542693

By:

Karhan, Ogur;
İleri, Serdar;
Urakçı, Zuhat;
Arvas, Hayati;
Kılıç, Delyadıl Karakaş;
Sezgin, Yasin;
Erçek, Berrak Merit;
Tunç, Sezai

Publication type:

Article

Efficacy and safety of guselkumab in patients with active lupus nephritis: results from a phase 2, randomized, placebo-controlled study Open Access.

Published in:

Rheumatology, 2025, v. 64, n. 5, p. 2731, doi. 10.1093/rheumatology/keae647

By:

Anders, Hans-Joachim;
Chan, Tak Mao;
Sanchez-Guerrero, Jorge;
Wofsy, David;
Bensley, Karen;
Kim, Lilianne;
Lo, Kim Hung;
Shu, Cathye;
Shao, Jie;
Karyekar, Chetan S;
Diamond, Betty

Publication type:

Article

Temporal and regional variation in the use of biologic and targeted synthetic DMARDs for rheumatoid arthritis: a nationwide cohort study Open Access.

Published in:

Rheumatology, 2025, v. 64, n. 5, p. 2432, doi. 10.1093/rheumatology/keae607

By:

Russell, Mark D;
Yang, Zijing;
Dooley, Niamh;
Gibson, Mark;
Zuckerman, Benjamin;
Adas, Maryam A;
Alveyn, Edward;
Patel, Samir;
Bechman, Katie;
Price, Elizabeth;
Gallagher, Sarah;
Coalwood, Callum;
Cope, Andrew P;
Norton, Sam;
Galloway, James B

Publication type:

Article

Multi-domain effectiveness of guselkumab evaluated via composite indices through 1 year in patients with PsA and inadequate response to TNFi: post hoc analysis of COSMOS Open Access.

Published in:

Rheumatology, 2025, v. 64, n. 5, p. 2565, doi. 10.1093/rheumatology/keae586

By:

Gossec, Laure;
Baraliakos, Xenofon;
Aletaha, Daniel;
Sharaf, Mohamed;
Rampakakis, Emmanouil;
Lavie, Frédéric;
López-Medina, Clementina;
Selmi, Carlo;
Coates, Laura C

Publication type:

Article

Majeed syndrome: first description in a patient of central-European ancestry Open Access.

Published in:

Rheumatology, 2025, v. 64, n. 5, p. 3069, doi. 10.1093/rheumatology/keae480

By:

Drago, Enrico;
Bertoni, Arinna;
Grossi, Alice;
Damasio, Maria Beatrice;
Anfigeno, Lorenzo;
Miano, Maurizio;
Papa, Riccardo;
Volpi, Stefano;
Ceccherini, Isabella;
Gattorno, Marco;
Caorsi, Roberta

Publication type:

Article

A Systematic Review and Classification of the Effects of P-glycoprotein Inhibitors and Inducers in Humans, Using Digoxin, Fexofenadine, and Dabigatran as Probe Drugs.

Published in:

Clinical Pharmacokinetics, 2025, v. 64, n. 6, p. 849, doi. 10.1007/s40262-025-01514-3

By:

Coumau, Claire;
Csajka, Chantal

Publication type:

Article

Advanced development of chemical inhibitors in water-based drilling fluids to improve shale stability: A review.

Published in:

Petroleum Science (KeAi Communications Co.), 2025, v. 22, n. 5, p. 1977, doi. 10.1016/j.petsci.2025.03.012

By:

Qiang Li;
Dao-Yi Zhu;
Guan-Zheng Zhuang;
Xin-Liang Li

Publication type:

Article

Skeletal Muscle Density as a Predictive Marker for Pathologic Complete Response in Triple-Negative Breast Cancer Treated with Neoadjuvant Chemoimmunotherapy.

Published in:

Cancers, 2025, v. 17, n. 11, p. 1768, doi. 10.3390/cancers17111768

By:

Mun, Han Song;
Kim, Sung Hun;
Lee, Jieun;
Park, Se Jun;
Lee, Ahwon;
Kang, Jun;
Park, Woo-Chan;
Bae, Soo Youn;
Choi, Byung Ok;
Hong, Ji Hyun;
Oh, Soon Nam;
Shin, Kabsoo

Publication type:

Article

Purine xanthine oxidase inhibitors are not conducive to the prognosis of chronic heart failure: a meta-analysis.

Published in:

European Journal of Clinical Pharmacology, 2025, v. 81, n. 7, p. 1069, doi. 10.1007/s00228-025-03848-0

By:

Ye, Lin;
Xu, Anyi;
Huang, Jianing;
Zhang, Yeyuan;
Yao, Jie;
Wang, Fang

Publication type:

Article

Letter to the editor: Relevant errors in a systematic review and network meta-analysis evaluating the efficacy and safety of different pharmacological interventions in the treatment of tardive dyskinesia.

Published in:

2025

By:

Correll, Christoph U.;
Rowe, David;
Ribalov, Rinat;
Campos, Verena Ramirez;
Solmi, Marco

Publication type:

Letter to the Editor

A case of pulmonary and cutaneous sarcoidosis.

Published in:

Breathe, 2025, v. 21, n. 2, p. 1, doi. 10.1183/20734735.0228-2024

By:

Foley, Eimear;
Basirat, Ahmad;
Yadav, Ankit;
O'Brien, Shane;
Mitchell, Patrick D.;
Donnelly, Seamas C.

Publication type:

Article

Structural mechanisms of PIP2 activation and SEA0400 inhibition in human cardiac sodium- calcium exchanger NCX1.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.105396

By:

Jing Xue;
Weizhong Zeng;
John, Scott;
Attiq, Nicole;
Ottolia, Michela;
Youxing Jiang

Publication type:

Article

A Comprehensive Review of Antinutrients in Plant‐Based Foods and Their Key Ingredients.

Published in:

Nutrition Bulletin, 2025, v. 50, n. 2, p. 171, doi. 10.1111/nbu.12732

By:

Yılmaz Tuncel, Neşe;
Polat Kaya, Havva;
Andaç, Ali Emre;
Korkmaz, Fatma;
Tuncel, Necati Barış

Publication type:

Article

A comparative experimental evaluation of the performance of additive compounds for inhibition of asphaltene precipitation from crude oil.

Published in:

Energy Sources Part A: Recovery, Utilization & Environmental Effects, 2025, v. 47, n. 1, p. 7113, doi. 10.1080/15567036.2021.1916131

By:

Alizadeh, Shahin;
Fazelipour, Fariborz;
Mousavi, Seyedeh Maryam;
Mansourian, Reza;
Qajar, Jafar

Publication type:

Article

Impact of adding urine alkalization therapy to xanthine oxidase inhibitor in gout management: a prospective cohort study Open Access.

Published in:

Rheumatology, 2025, v. 64, n. 6, p. 3509, doi. 10.1093/rheumatology/keaf091

By:

Wang, Can;
Guo, Kai;
Dalbeth, Nicola;
Sun, Mingshu;
Lu, Jie;
Chen, Ying;
Zhang, Hui;
Wang, Xuefeng;
Ji, Xiaopeng;
Li, Xinde;
Sun, Wenyan;
Han, Lin;
Cui, Lingling;
Liu, Zhen;
Ji, Aichang;
He, Yuwei;
Terkeltaub, Robert;
Li, Changgui

Publication type:

Article

Anti-Amyloid Drugs in Alzheimer's Disease: A Narrative Review.

Published in:

2025

By:

Pereira, Will;
Thiyagalingam, Shanojan

Publication type:

Abstract

Investigating the potential of prenylated and geranylated acylphloroglucinol-based xanthenones as potent soybean 15-lipoxygenase inhibitors: a combined in vitro and in silico approach.

Published in:

Pure & Applied Chemistry, 2025, v. 97, n. 6, p. 593, doi. 10.1515/pac-2024-0356

By:

Tamil Segaran, Raaginie;
Mohd Aluwi, Mohd Fadhlizil Fasihi;
Lam, Kok Wai;
Shaari, Khozirah;
Md Pisar, Mazura;
Mohd Hashim, Siti Nur Aisyah;
Imran, Syahrul;
Ng, Chean Hui

Publication type:

Article

Evaluation of 2-(1H-1,2,3-triazol-1-yl) acetic acid derivatives as potential human hypoxia-inducible factor (HIF) prolyl hydroxylase domain-2 (PHD2) inhibitors.

Published in:

Pure & Applied Chemistry, 2025, v. 97, n. 6, p. 625, doi. 10.1515/pac-2024-0301

By:

Sayaf, Abrar Mohammad;
Cheah, June Sun;
Khan, Abbas;
Schofield, Christopher J.;
Agouni, Abdelali;
Yeoh, Kar Kheng

Publication type:

Article

Contact phase inhibitors: the future of anticoagulation?

Published in:

Journal of Laboratory Medicine, 2025, v. 49, n. 3, p. 97, doi. 10.1515/labmed-2024-0167

By:

Veyrat, Angèle;
Depasse, François;
Feriel, Joffrey

Publication type:

Article

MDM2 as a therapeutic target in advanced biliary tract cancers.

Published in:

Oncologist, 2025, v. 30, n. 5, p. 1, doi. 10.1093/oncolo/oyaf094

By:

Spencer, Kristen R;
King, Gentry G

Publication type:

Article

Decoding NATALEE and MonarchE eligibility criteria in a real-world cohort of early breast cancer patients.

Published in:

Oncologist, 2025, v. 30, n. 5, p. 1, doi. 10.1093/oncolo/oyaf061

By:

Canzian, Jacopo;
Gentile, Damiano;
Sanctis, Rita De;
Jacobs, Flavia;
Benvenuti, Chiara;
Gaudio, Mariangela;
Gerosa, Riccardo;
Saltalamacchia, Giuseppe;
Torrisi, Rosalba;
Masci, Giovanna;
Tinterri, Corrado;
Zambelli, Alberto

Publication type:

Article

Efficacy of 2 different fibroblast growth factor receptor-inhibitors in a patient with extrahepatic cholangiocarcinoma harboring an FGFR2 mutation: a case report.

Published in:

Oncologist, 2025, v. 30, n. 5, p. 1, doi. 10.1093/oncolo/oyae294

By:

Galli-Vareia, Ilianna;
Szturz, Petr;
Voutsadakis, Ioannis A;
Villard, Nicolas;
Tsoumakidou, Georgia;
Fleury, Mapi;
Herrera, Gabriela;
Fasquelle, Francois;
Godat, Sebastien;
Digklia, Antonia

Publication type:

Article

Real-World Experience with Venetoclax Treatment for Newly-Diagnosed Acute Myeloid Leukemia in Japan (VENUS Study): An Interim Analysis Focusing on Neutropenia Management.

Published in:

Oncology & Therapy, 2025, v. 13, n. 2, p. 519, doi. 10.1007/s40487-025-00329-3

By:

Goto, Tatsunori;
Numata, Hiroki;
Katsuoka, Yuna;
Uoshima, Nobuhiko;
Hara, Satoru;
Ando, Jun;
Ota, Shuichi;
Yoshimoto, Goichi;
Matsuoka, Akihito;
Hashiba, Hideyuki;
Morita, Tetsuo;
Tsutsui, Atsuko;
Imanaka, Ryota

Publication type:

Article

Levocarnitine inhibits tumor necrosis factor alpha-induced vascular cell adhesion molecule 1 expression.

Published in:

Renal Replacement Therapy, 2025, v. 11, n. 1, p. 1, doi. 10.1186/s41100-025-00631-w

By:

Misawa, Hideo;
Yamadera, Shiho;
Nakamura, Yuya;
Inagaki, Masahiro;
Oguchi, Tatsunori;
Tsuji, Yuya;
Tsuji, Mayumi;
Ohsawa, Isao;
Gotoh, Hiromichi;
Kiuchi, Yuji

Publication type:

Article

Targeting Prostate Cancer Cells by an Isopeptidase Inhibitor NSC632839.

Published in:

Urology Research & Practice, 2025, v. 51, n. 1, p. 33, doi. 10.5152/tud.2025.24115

By:

Demir, Ummuhan;
Erdogdu, Rabia

Publication type:

Article

INNOVATIVE EXTRACTION METHODS AND SOLVENT OPTIMIZATION FOR PAEDERIA FOETIDA IN VITRO ANALYSIS OF ANTIOXIDANT AND NEUROPROTECTIVE PROPERTIES.

Published in:

Bulletin of Pure & Applied Sciences-Zoology, 2024, v. 43B, p. 976

By:

Tripathi, Gireesh;
Kriti, Komal;
Kavitha S.;
Asokan, B. R.;
Pimpalshende, Pankaj Mohan;
Roy, Dilip Kumar;
Samanta, Anuva;
Krishna, Konda V. V. S.

Publication type:

Article

Sustainable Corrosion Prevention: A Theoretical Synthesis of Renewable Materials and Bio-Inhibitors.

Published in:

Journal of Research & Innovation for Sustainable Society (JRISS), 2025, v. 7, n. 1, p. 138, doi. 10.33727/JRISS.2025.1.13:138-149

By:

Olisakwe, Henry Chukwuemeka;
Ninduwezuor-Ehiobu, Nwakamma;
Ejike Ewim, Daniel Raphael

Publication type:

Article

Biological Evaluation of Panaxadiol Derivatives as Inhibitors of ALK5.

Published in:

Chemistry of Natural Compounds, 2025, v. 61, n. 3, p. 487, doi. 10.1007/s10600-025-04684-5

By:

Jiang, Dianzhuo;
Zhang, Tianyi;
Jin, Ke;
Zhang, Jinfeng;
Bi, Yongsheng;
Yu, Fei

Publication type:

Article

Tirbanibulin ointment 1% in actinic keratosis: a profile of its use in the USA.

Published in:

Drugs & Therapy Perspectives, 2025, v. 41, n. 5, p. 169, doi. 10.1007/s40267-025-01158-0

By:

McGuigan, Aisling;
Syed, Yahiya Y.

Publication type:

Article

ADAM Proteases in Cancer: Biological Roles, Therapeutic Challenges, and Emerging Opportunities.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1703, doi. 10.3390/cancers17101703

By:

Arora, Sakshi;
Scott, Andrew M.;
Janes, Peter W.

Publication type:

Article