Works matching DE "CHECKPOINT kinase 1"

Results: 161

An effective kinase inhibition strategy for metastatic recurrent childhood medulloblastoma.

Published in:

Journal of Neuro-Oncology, 2023, v. 163, n. 3, p. 635, doi. 10.1007/s11060-023-04372-w

By:

Adile, Ashley A.;
Bakhshinyan, David;
Suk, Yujin;
Uehling, David;
Saini, Mehakpreet;
Aman, Ahmed;
Magolan, Jakob;
Subapanditha, Minomi K.;
McKenna, Dillon;
Chokshi, Chirayu;
Savage, Neil;
Kameda-Smith, Michelle M.;
Venugopal, Chitra;
Singh, Sheila K.

Publication type:

Article

A cellular senescence-related signature for predicting prognosis, immunotherapy response, and candidate drugs in patients treated with transarterial chemoembolization (TACE).

Published in:

Discover Oncology, 2024, v. 15, n. 1, p. 1, doi. 10.1007/s12672-024-01116-8

By:

He, Ning;
Zhao, Wenjing;
Tian, Wenlong;
Wu, Ying;
Xu, Jian;
Lu, Yunyan;
Chen, Xudong;
Zhao, Hui

Publication type:

Article

Multiple 9-1-1 complexes promote homolog synapsis, DSB repair, and ATR signaling during mammalian meiosis.

Published in:

eLife, 2022, p. 1, doi. 10.7554/eLife.68677

By:

Pereira, Catalina;
Arroyo-Martinez, Gerardo A.;
Guo, Matthew Z.;
Downey, Michael S.;
Kelly, Emma R.;
Grive, Kathryn J.;
Mahadevaiah, Shantha K.;
Sims, Jennie R.;
Faca, Vitor M.;
Tsai, Charlton;
Schiltz, Carl J.;
Wit, Niek;
Jacobs, Heinz;
Clark, Nathan L.;
Freire, Raimundo;
Turner, James;
Lyndaker, Amy M.;
Brieno-Enriquez, Miguel A.;
Cohen, Paula E.;
Smolka, Marcus B.

Publication type:

Article

Advances in ATM, ATR, WEE1, and CHK1/2 inhibitors in the treatment of PARP inhibitor-resistant ovarian cancer.

Published in:

Cancer Biology & Medicine, 2023, v. 20, n. 12, p. 915, doi. 10.20892/j.issn.2095-3941.2023.0260

By:

Qin Tang;
Xin Wang;
Haixia Wang;
Lin Zhong;
Dongling Zou

Publication type:

Article

Liquid-liquid phase separation in DNA double-strand break repair.

Published in:

Cancer Biology & Medicine, 2023, v. 20, n. 9, p. 627, doi. 10.20892/j.issn.2095-3941.2023.0252

By:

Jia Chen;
Jie Shi;
Jian Zheng;
Yunlong Wang;
Xiangbo Wan

Publication type:

Article

Chromosome 11q loss and MYCN amplification demonstrate synthetic lethality with checkpoint kinase 1 inhibition in neuroblastoma.

Published in:

Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.929123

By:

Keller, Kaylee M.;
Eleveld, Thomas F.;
Schild, Linda;
den Handel, Kim van;
den Boogaard, Marlinde van;
Amo-Addae, Vicky;
Eising, Selma;
Ober, Kimberley;
Koopmans, Bianca;
Looijenga, Leendert;
Tytgat, Godelieve A. M.;
Ylstra, Bauke;
Molenaar, Jan J.;
Dolman, M. Emmy M.;
van Hooff, Sander R.

Publication type:

Article

Chk1 Inhibition Hinders the Restoration of H3.1K56 and H3.3K56 Acetylation and Reprograms Gene Transcription After DNA Damage Repair.

Published in:

Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.862592

By:

Ding, Nan;
Shao, Zhiang;
Yuan, Fangyun;
Qu, Pei;
Li, Ping;
Lu, Dong;
Wang, Jufang;
Zhu, Qianzheng

Publication type:

Article

Synergistic targeting of CHK1 and mTOR in MYC-driven tumors.

Published in:

Carcinogenesis, 2021, v. 42, n. 3, p. 448, doi. 10.1093/carcin/bgaa119

By:

Song, Xiaoxue;
Wang, Liyuan;
Wang, Tianci;
Hu, Juncheng;
Wang, Jingchao;
Tu, Rongfu;
Su, Hexiu;
Jiang, Jue;
Qing, Guoliang;
Liu, Hudan

Publication type:

Article

Novel therapeutic approach for uterine leiomyosarcoma based on transcriptome analysis.

Published in:

Journal of Gynecologic Oncology, 2022, v. 33, p. S1, doi. 10.3802/jgo.2022.33.S1

By:

Kosuke Yoshida;
Akira Yokoi;
Tomoyasu Kato;
Hiroaki Kajiyama

Publication type:

Article

The thioredoxin system determines CHK1 inhibitor sensitivity via redox-mediated regulation of ribonucleotide reductase activity.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-48076-9

By:

Prasad, Chandra Bhushan;
Oo, Adrian;
Liu, Yujie;
Qiu, Zhaojun;
Zhong, Yaogang;
Li, Na;
Singh, Deepika;
Xin, Xiwen;
Cho, Young-Jae;
Li, Zaibo;
Zhang, Xiaoli;
Yan, Chunhong;
Zheng, Qingfei;
Wang, Qi-En;
Guo, Deliang;
Kim, Baek;
Zhang, Junran

Publication type:

Article

H6P2W18O62·18H2O as a Recyclable Catalyst for Synthesis of Tetrahydrobenzo[b]pyrans.

Published in:

Organic Preparations & Procedures International, 2024, v. 56, n. 6, p. 572, doi. 10.1080/00304948.2024.2342678

By:

Mohamadpour, Farzaneh

Publication type:

Article

Visible Light Assisted Synthesis of Tetrahydrobenzo[b]pyrans Using 4CzIPN, a Carbazole-Based Photocatalyst.

Published in:

Organic Preparations & Procedures International, 2024, v. 56, n. 4, p. 317, doi. 10.1080/00304948.2023.2296180

By:

Mohamadpour, Farzaneh

Publication type:

Article

Synthesis of Tetrahydrobenzo[b]pyrans Promoted by Sodium Stearate as a Lewis Base-Surfactant Combined Catalyst in an Aqueous Micellar Medium.

Published in:

Organic Preparations & Procedures International, 2023, v. 55, n. 4, p. 345, doi. 10.1080/00304948.2022.2151812

By:

Mohamadpour, Farzaneh

Publication type:

Article

Green Approach for Metal-free One-pot Synthesis of Tetrahydrobenzo[b]pyrans with Sodium Alginate as a Reusable Bifunctional Biopolymeric Catalyst.

Published in:

Organic Preparations & Procedures International, 2022, v. 54, n. 4, p. 306, doi. 10.1080/00304948.2022.2037369

By:

Mohamadpour, Farzaneh

Publication type:

Article

Identification of CHK1 Kinase Inhibitors Using Structure-Based Pharmacophore Modelling and Molecular Docking.

Published in:

Indian Journal of Pharmaceutical Sciences, 2020, v. 82, n. 3, p. 472, doi. 10.36468/pharmaceutical-sciences.670

By:

AL-SHAR'I, N. A.;
MUSLEH, SONDOS

Publication type:

Article

Orchestrating smart therapeutics to achieve optimal treatment in small cell lung cancer: recent progress and future directions.

Published in:

Journal of Translational Medicine, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12967-023-04338-6

By:

Zhang, Chenyue;
Zhang, Chenxing;
Wang, Kai;
Wang, Haiyong

Publication type:

Article

Regulation of Mus81-Eme1 structure-specific endonuclease by Eme1 SUMO-binding and Rad3ATR kinase is essential in the absence of Rqh1BLM helicase.

Published in:

PLoS Genetics, 2022, v. 18, n. 4, p. 1, doi. 10.1371/journal.pgen.1010165

By:

Giaccherini, Cédric;
Scaglione, Sarah;
Coulon, Stéphane;
Dehé, Pierre-Marie;
Gaillard, Pierre-Henri L.

Publication type:

Article

Targeting Replication Stress Response Pathways to Enhance Genotoxic Chemo- and Radiotherapy.

Published in:

Molecules, 2022, v. 27, n. 15, p. 4736, doi. 10.3390/molecules27154736

By:

Nickoloff, Jac A.

Publication type:

Article

Benzothiazole and Chromone Derivatives as Potential ATR Kinase Inhibitors and Anticancer Agents.

Published in:

Molecules, 2022, v. 27, n. 14, p. N.PAG, doi. 10.3390/molecules27144637

By:

Frasinyuk, Mykhaylo;
Chhabria, Dimple;
Kartsev, Victor;
Dilip, Haritha;
Sirakanyan, Samvel N.;
Kirubakaran, Sivapriya;
Petrou, Anthi;
Geronikaki, Athina;
Spinelli, Domenico

Publication type:

Article

Correction: Ionizing radiation induces ataxia telangiectasia mutated kinase (ATM)-mediated phosphorylation of LKB1/STK11 at Thr-366.

Published in:: Biochemical Journal, 2025, v. 482, n. 7, p. 359, doi. 10.1042/BJ20021284_COR
Publication type:: Article

Regulation of CHK1 inhibitor resistance by a c-Rel and USP1 dependent pathway.

Published in:

Biochemical Journal, 2022, v. 479, n. 19, p. 2063, doi. 10.1042/BCJ20220102

By:

Hunter, Jill E.;
Campbell, Amy E.;
Hannaway, Nicola L.;
Kerridge, Scott;
Luli, Saimir;
Butterworth, Jacqueline A.;
Sellier, Helene;
Mukherjee, Reshmi;
Dhillon, Nikita;
Sudhindar, Praveen D.;
Shukla, Ruchi;
Brownridge, Philip J.;
Bell, Hayden L.;
Coxhead, Jonathan;
Taylor, Leigh;
Leary, Peter;
Hasoon, Megan S. R.;
Collins, Ian;
Garrett, Michelle D.;
Eyers, Claire E.

Publication type:

Article

Mutation of the RelA(p65) Thr505 phosphosite disrupts the DNA replication stress response leading to CHK1 inhibitor resistance.

Published in:

Biochemical Journal, 2022, v. 479, n. 19, p. 2087, doi. 10.1042/BCJ20220089

By:

Hunter, Jill E.;
Campbell, Amy E.;
Butterworth, Jacqueline A.;
Sellier, Helene;
Hannaway, Nicola L.;
Luli, Saimir;
Floudas, Achilleas;
Kenneth, Niall S.;
Moore, Adam J.;
Brownridge, Philip J.;
Thomas, Huw D.;
Coxhead, Jonathan;
Taylor, Leigh;
Leary, Peter;
Hasoon, Megan S. R.;
Knight, Andrew M.;
Garrett, Michelle D.;
Collins, Ian;
Eyers, Claire E.;
Perkins, Neil D.

Publication type:

Article

Up-regulation of the PI3K/AKT and RHO/RAC/PAK signalling pathways in CHK1 inhibitor resistant Eµ-Myc lymphoma cells.

Published in:

Biochemical Journal, 2022, v. 479, n. 19, p. 2131, doi. 10.1042/BCJ20220103

By:

Hunter, Jill E.;
Campbell, Amy E.;
Kerridge, Scott;
Fraser, Callum;
Hannaway, Nicola L.;
Luli, Saimir;
Ivanova, Iglika;
Brownridge, Philip J.;
Coxhead, Jonathan;
Taylor, Leigh;
Leary, Peter;
Hasoon, Megan S. R.;
Eyers, Claire E.;
Perkins, Neil D.

Publication type:

Article

Glyco you should know.

Published in:

Glycobiology, 2025, v. 35, n. 4, p. 1, doi. 10.1093/glycob/cwaf008

By:

Massman, Lilyanna

Publication type:

Article

Identifying and overcoming a mechanism of resistance to WEE1 kinase inhibitor AZD1775 in high grade serous ovarian cancer cells.

Published in:

European Journal of Gynaecological Oncology, 2022, v. 43, n. 2, p. 183, doi. 10.31083/j.ejgo4302024

By:

Gomez, Miriam K.;
Thomson, John P.;
Grimes, Graeme R.;
Wang, Anderson T.;
Churchman, Michael;
O'Connor, Mark J.;
Gourley, Charlie;
Melton, David W.

Publication type:

Article

BUB- 1 and CENP- C recruit PLK- 1 to control chromosome alignment and segregation during meiosis I in C. elegans oocytes.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.84057

By:

Taylor, Samuel JP;
Borja, Laura Bel;
Soubigou, Flavie;
Houston, Jack;
Cheerambathur, Dhanya K.;
Pelisch, Federico

Publication type:

Article

Enhanced Efficacy of Combined Therapy with Checkpoint Kinase 1 Inhibitor and Rucaparib via Regulation of Rad51 Expression in BRCA Wild-Type Epithelial Ovarian Cancer Cells.

Published in:

Cancer Research & Treatment, 2021, v. 53, n. 3, p. 819, doi. 10.4143/crt.2020.1013

By:

Hye-yon Cho;
Yong-Beom Kim;
Wook-ha Park;
Jae Hong No

Publication type:

Article

Exploration of the carcinogenetic and immune role of CHK1 in human cancer.

Published in:

Journal of Cancer, 2024, v. 15, n. 18, p. 5927, doi. 10.7150/jca.93930

By:

Jian Zhou;
Ziyi Wu;
Aili, Dilihumaer;
Lu Wang;
Tang Liu

Publication type:

Article

Histone H3 serine-57 is a CHK1 substrate whose phosphorylation affects DNA repair.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-40843-4

By:

Parisis, Nikolaos;
Dans, Pablo D.;
Jbara, Muhammad;
Singh, Balveer;
Schausi-Tiffoche, Diane;
Molina-Serrano, Diego;
Brun-Heath, Isabelle;
Hendrychová, Denisa;
Maity, Suman Kumar;
Buitrago, Diana;
Lema, Rafael;
Nait Achour, Thiziri;
Giunta, Simona;
Girardot, Michael;
Talarek, Nicolas;
Rofidal, Valérie;
Danezi, Katerina;
Coudreuse, Damien;
Prioleau, Marie-Noëlle;
Feil, Robert

Publication type:

Article

An ATR-PrimPol pathway confers tolerance to oncogenic KRAS-induced and heterochromatin-associated replication stress.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-40578-2

By:

Igarashi, Taichi;
Mazevet, Marianne;
Yasuhara, Takaaki;
Yano, Kimiyoshi;
Mochizuki, Akifumi;
Nishino, Makoto;
Yoshida, Tatsuya;
Yoshida, Yukihiro;
Takamatsu, Nobuhiko;
Yoshimi, Akihide;
Shiraishi, Kouya;
Horinouchi, Hidehito;
Kohno, Takashi;
Hamamoto, Ryuji;
Adachi, Jun;
Zou, Lee;
Shiotani, Bunsyo

Publication type:

Article

Dynamic structural remodeling of LINC01956 enhances temozolomide resistance in MGMT-methylated glioblastoma.

Published in:

Science Translational Medicine, 2024, v. 16, n. 767, p. 1, doi. 10.1126/scitranslmed.ado1573

By:

Liao, Xinyi;
Zhang, Shuxia;
Li, Xincheng;
Qian, Wanying;
Li, Man;
Chen, Suwen;
Wu, Xingui;
Yu, Xuexin;
Li, Ziwen;
Tang, Miaoling;
Xu, Yingru;
Yu, Ruyuan;
Zhang, Qiliang;
Wu, Geyan;
Zhang, Nu;
Song, Libing;
Li, Jun

Publication type:

Article

Expression and prognostic significance of the P53‐related DNA damage repair proteins checkpoint kinase 1 (CHK1) and growth arrest and DNA‐damage‐inducible 45 alpha (GADD45A) in human oral squamous cell carcinoma.

Published in:

European Journal of Oral Sciences, 2020, v. 128, n. 2, p. 128, doi. 10.1111/eos.12685

By:

Xie, Liping;
Jia, Limin;
Qu, Jinyue;
Chen, Dong;
Lv, Yanhong;
Li, Haixia;
Zheng, Jinhua

Publication type:

Article

DAP3-mediated cell cycle regulation and its association with radioresistance in human lung adenocarcinoma cell lines.

Published in:

Journal of Radiation Research, 2023, v. 64, n. 3, p. 520, doi. 10.1093/jrr/rrad016

By:

Sato, Yoshiaki;
Yoshino, Hironori;
Sato, Kota;
Kashiwakura, Ikuo;
Tsuruga, Eichi

Publication type:

Article

CHEK1 and circCHEK1_246aa evoke chromosomal instability and induce bone lesion formation in multiple myeloma.

Published in:

Molecular Cancer, 2021, v. 20, n. 1, p. 1, doi. 10.1186/s12943-021-01380-0

By:

Gu, Chunyan;
Wang, Wang;
Tang, Xiaozhu;
Xu, Tingting;
Zhang, Yanxin;
Guo, Mengjie;
Wei, Rongfang;
Wang, Yajun;
Jurczyszyn, Artur;
Janz, Siegfried;
Beksac, Meral;
Zhan, Fenghuang;
Seckinger, Anja;
Hose, Dirk;
Pan, Jingxuan;
Yang, Ye

Publication type:

Article

Semilicoisoflavone B induces oral cancer cell apoptosis by targeting claspin and ATR‐Chk1 signaling pathways.

Published in:

Environmental Toxicology, 2024, v. 39, n. 4, p. 2417, doi. 10.1002/tox.24107

By:

Hsieh, Ming‐Ju;
Lin, Chia‐Chieh;
Lo, Yu‐Sheng;
Chuang, Yi‐Ching;
Ho, Hsin‐Yu;
Chen, Mu‐Kuan

Publication type:

Article

Allyl isothiocyanate induces DNA damage and inhibits DNA repair‐associated proteins in a human gastric cancer cells in vitro.

Published in:

Environmental Toxicology, 2024, v. 39, n. 3, p. 1303, doi. 10.1002/tox.24020

By:

Shih, Yung‐Luen;
Hsu, Sheng‐Yao;
Lai, Kuang‐Chi;
Chueh, Fu‐Shin;
Huang, Yuan‐Li;
Kuo, Chao‐Lin;
Chen, Yung‐Liang;
Chen, Chiung‐Ju;
Peng, Shu‐Fen;
Huang, Wen‐Wen;
Lu, Hsu‐Fen

Publication type:

Article

421 Specific cephalosporin antibiotics deplete tumor PD-L1 to inhibit DNA damage sensing and sensitize to Chk1 inhibitors in vivo.

Published in:

2022

By:

Murray, Clare;
Kornepati, Anand;
Padron, Alvaro;
Deng, Yilun;
Garcia, Myrna;
Bai, Haiyan;
Curiel, Tyler

Publication type:

Abstract

New perspective on DNA response pathway (DDR) in glioblastoma, focus on classic biomarkers and emerging roles of ncRNAs.

Published in:

Expert Reviews in Molecular Medicine, 2023, v. 25, p. 1, doi. 10.1017/erm.2023.10

By:

Pirlog, Bianca Oana;
Ilut, Silvina;
Pirlog, Radu;
Chiroi, Paul;
Nutu, Andreea;
Radutiu, Delia Ioana;
Cuc, George Daniel;
Berindan-Neagoe, Ioana;
Nabavi, Seyed Fazel;
Filosa, Rosanna;
Nabavi, Seyed Mohammad

Publication type:

Article

DNA damage checkpoint kinases in cancer.

Published in:

Expert Reviews in Molecular Medicine, 2020, v. 22, p. 1, doi. 10.1017/erm.2020.3

By:

Smith, Hannah L.;
Southgate, Harriet;
Tweddle, Deborah A.;
Curtin, Nicola J.

Publication type:

Article

Cytarabine-induced differentiation of AML cells depends on Chk1 activation and shares the mechanism with inhibitors of DHODH and pyrimidine synthesis.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-15520-z

By:

Tomic, Barbara;
Smoljo, Tomislav;
Lalic, Hrvoje;
Dembitz, Vilma;
Batinic, Josip;
Batinic, Drago;
Bedalov, Antonio;
Visnjic, Dora

Publication type:

Article

Cell cycle arrest is an important mechanism of action of compound Kushen injection in the prevention of colorectal cancer.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-08336-4

By:

Sun, Jie;
Li, Mei;
Lin, Tingru;
Wang, Di;
Chen, Jingyi;
Zhang, Yu;
Mu, Qing;
Su, Huiting;
Wu, Na;
Liu, Aiyu;
Yu, Yimeng;
Liu, Yulan;
Wang, Shaojie;
Yu, Xin;
Guo, Jingzhu;
Yu, Weidong

Publication type:

Article

Combined inhibition of Wee1 and Chk1 as a therapeutic strategy in multiple myeloma.

Published in:

Frontiers in Oncology, 2023, p. 1, doi. 10.3389/fonc.2023.1271847

By:

Bruyer, Angélique;
Dutrieux, Laure;
de Boussac, Hugues;
Martin, Thibaut;
Chemlal, Djamila;
Robert, Nicolas;
Requirand, Guilhem;
Cartron, Guillaume;
Vincent, Laure;
Herbaux, Charles;
Lutzmann, Malik;
Bret, Caroline;
Pasero, Philippe;
Moreaux, Jérôme;
Ovejero, Sara

Publication type:

Article

Identification of hub genes and their correlation with infiltration of immune cells in MYCN positive neuroblastoma based on WGCNA and LASSO algorithm.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.1016683

By:

Ji Chen;
Mengjiao Sun;
Chuqin Chen;
Bin Jiang;
Yongjun Fang

Publication type:

Article

Ubiquitination of the DNA-damage checkpoint kinase CHK1 by TRAF4 is required for CHK1 activation.

Published in:

Journal of Hematology & Oncology, 2020, v. 13, n. 1, p. 1, doi. 10.1186/s13045-020-00869-3

By:

Yu, Xinfang;
Li, Wei;
Liu, Haidan;
Deng, Qipan;
Wang, Xu;
Hu, Hui;
Xu-Monette, Zijun Y.;
Xiong, Wei;
Lu, Zhongxin;
Young, Ken H.;
Wang, Wei;
Li, Yong

Publication type:

Article

KPT330 promotes the sensitivity of glioblastoma to olaparib by retaining SQSTM1 in the nucleus and disrupting lysosomal function.

Published in:

Autophagy, 2024, v. 20, n. 2, p. 295, doi. 10.1080/15548627.2023.2252301

By:

Wang, Li-Hong;
Wei, Sen;
Yuan, Ye;
Zhong, Ming-Jun;
Wang, Jiao;
Yan, Ze-Xuan;
Zhou, Kai;
Luo, Tao;
Liang, Li;
Bian, Xiu-Wu

Publication type:

Article

Identification of formononetin as the active compound of CR‐SR in hepatocellular carcinoma treatment: An integrated approach combining network pharmacology and weighted gene co‐expression networks.

Published in:

Chemical Biology & Drug Design, 2024, v. 103, n. 1, p. 1, doi. 10.1111/cbdd.14363

By:

Li, Chun;
Xie, Yuxin;
Hu, Shaoyu;
Yu, Hong;
Xu, Yunke;
Shen, Hongping;
Yuan, Yuan;
Gu, Long;
Pu, Bangming

Publication type:

Article

Anticancer potentiating effect and downregulation of PD‐L1 expression: Study on the 2‐[(p‐fluorophenyl)amino]‐6‐substituted‐9H‐purine analogues as novel CHK1 inhibitors.

Published in:

Chemical Biology & Drug Design, 2023, v. 101, n. 3, p. 626, doi. 10.1111/cbdd.14156

By:

Chen, Xuanzhen;
Wang, Meng;
Wang, Xiaowei;
Liu, Junyi;
Zhang, Zhili;
Tian, Chao

Publication type:

Article

Proapoptotic activity of JNK-sensitive BH3-only proteins underpins ovarian cancer response to replication checkpoint inhibitors.

Published in:

Molecular Cancer, 2024, v. 23, n. 1, p. 1, doi. 10.1186/s12943-024-02125-5

By:

Venkatachalam, Annapoorna;
Correia, Cristina;
Peterson, Kevin L.;
Hou, Xianon;
Schneider, Paula A.;
Strathman, Annabella R.;
Flatten, Karen S.;
Sine, Chance C.;
Balczewski, Emily A.;
McGehee, Cordelia D.;
Larson, Melissa C.;
Duffield, Laura N.;
Meng, X. Wei;
Vincelette, Nicole D.;
Ding, Husheng;
Oberg, Ann L.;
Couch, Fergus J.;
Swisher, Elizabeth M.;
Li, Hu;
Weroha, S. John

Publication type:

Article

Relative free-energy calculations for scaffold hopping-type transformations with an automated RE-EDS sampling procedure.

Published in:

Journal of Computer-Aided Molecular Design, 2022, v. 36, n. 2, p. 117, doi. 10.1007/s10822-021-00436-z

By:

Ries, Benjamin;
Normak, Karl;
Weiß, R. Gregor;
Rieder, Salomé;
Barros, Emília P.;
Champion, Candide;
König, Gerhard;
Riniker, Sereina

Publication type:

Article

The cytosolic iron–sulfur cluster assembly (CIA) pathway is required for replication stress tolerance of cancer cells to Chk1 and ATR inhibitors.

Published in:

NPJ Breast Cancer, 2021, v. 7, n. 1, p. 1, doi. 10.1038/s41523-021-00353-2

By:

Redwood, Abena B.;
Zhang, Xiaomei;
Seth, Sahil B.;
Ge, Zhongqi;
Bindeman, Wendy E.;
Zhou, Xinhui;
Sinha, Vidya C.;
Heffernan, Timothy P.;
Piwnica-Worms, Helen

Publication type:

Article