Works matching DE "CHAGAS' disease treatment"

Results: 201
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    Research news.

    Published in:
    Nature Medicine, 2000, v. 6, n. 2, p. 142, doi. 10.1038/72235
    By:
    • Novak, Kristine;
    • MacFarlane, John
    Publication type:
    Article
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    Squalene Synthase As a Target for Chagas Disease Therapeutics.

    Published in:
    PLoS Pathogens, 2014, v. 10, n. 5, p. 1, doi. 10.1371/journal.ppat.1004114
    By:
    • Shang, Na;
    • Li, Qian;
    • Ko, Tzu-Ping;
    • Chan, Hsiu-Chien;
    • Li, Jikun;
    • Zheng, Yingying;
    • Huang, Chun-Hsiang;
    • Ren, Feifei;
    • Chen, Chun-Chi;
    • Zhu, Zhen;
    • Galizzi, Melina;
    • Li, Zhu-Hong;
    • Rodrigues-Poveda, Carlos A.;
    • Gonzalez-Pacanowska, Dolores;
    • Veiga-Santos, Phercyles;
    • de Carvalho, Tecia Maria Ulisses;
    • de Souza, Wanderley;
    • Urbina, Julio A.;
    • Wang, Andrew H.-J.;
    • Docampo, Roberto
    Publication type:
    Article
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    Benznidazole treatment safety: the Médecins Sans Frontières experience in a large cohort of Bolivian patients with Chagas' disease.

    Published in:
    2017
    By:
    • da Silva, Gilberto Marcelo Sperandio;
    • Mediano, Mauro Felippe Felix;
    • Hasslocher-Moreno, Alejandro Marcel;
    • de Holanda, Marcelo Teixeira;
    • de Sousa, Andrea Silvestre;
    • Sangenis, Luiz Henrique Conde;
    • do Brasil, Pedro Emmanuel Alvarenga Americano;
    • Mejía, Roger Arteaga;
    • Fux, Carina Perotti;
    • Cubides, Juan-Carlos;
    • Saraiva, Roberto Magalhães;
    • Brum-Soares, Lucia Maria;
    • Sperandio da Silva, Gilberto Marcelo;
    • Felix Mediano, Mauro Felippe;
    • Holanda, Marcelo Teixeira de;
    • Silvestre de Sousa, Andrea;
    • Brasil, Pedro Emmanuel Alvarenga Americano do;
    • Mediano, M M F;
    • Mediano, M F F
    Publication type:
    journal article
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    Cynomolgus macaques naturally infected with Trypanosoma cruzi-I exhibit an overall mixed pro-inflammatory/modulated cytokine signature characteristic of human Chagas disease.

    Published in:
    PLoS Neglected Tropical Diseases, 2017, v. 11, n. 2, p. 1, doi. 10.1371/journal.pntd.0005233
    By:
    • Vitelli-Avelar, Danielle Marquete;
    • Sathler-Avelar, Renato;
    • Mattoso-Barbosa, Armanda Moreira;
    • Gouin, Nicolas;
    • Perdigão-de-Oliveira, Marcelo;
    • Valério-dos-Reis, Leydiane;
    • Costa, Ronaldo Peres;
    • Elói-Santos, Silvana Maria;
    • Gomes, Matheus de Souza;
    • Amaral, Laurence Rodrigues do;
    • Teixeira-Carvalho, Andréa;
    • Martins-Filho, Olindo Assis;
    • Jr.Dick, Edward J.;
    • Hubbard, Gene B.;
    • VandeBerg, Jane F.;
    • VandeBerg, John L.
    Publication type:
    Article
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    Pharmacophore Modeling for Anti-Chagas Drug Design Using the Fragment Molecular Orbital Method.

    Published in:
    PLoS ONE, 2015, v. 10, n. 5, p. 1, doi. 10.1371/journal.pone.0125829
    By:
    • Yoshino, Ryunosuke;
    • Yasuo, Nobuaki;
    • Inaoka, Daniel Ken;
    • Hagiwara, Yohsuke;
    • Ohno, Kazuki;
    • Orita, Masaya;
    • Inoue, Masayuki;
    • Shiba, Tomoo;
    • Harada, Shigeharu;
    • Honma, Teruki;
    • Balogun, Emmanuel Oluwadare;
    • da Rocha, Josmar Rodrigues;
    • Montanari, Carlos Alberto;
    • Kita, Kiyoshi;
    • Sekijima, Masakazu
    Publication type:
    Article
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    A protocol update for the Selenium Treatment and Chagasic Cardiomyopathy (STCC) trial.

    Published in:
    2018
    By:
    • Holanda, Marcelo Teixeira;
    • Mediano, Mauro Felippe Felix;
    • Hasslocher-Moreno, Alejandro Marcel;
    • Xavier, Sérgio Salles;
    • Saraiva, Roberto Magalhães;
    • Sousa, Andrea Silvestre;
    • Maciel, Erica Rodrigues;
    • Carneiro, Fernanda Martins;
    • da Silva, Paula Simplicio;
    • Sangenis, Luiz Henrique Conde;
    • Veloso, Henrique Horta;
    • Cardoso, Claudia Santos de Aguiar;
    • Bonecini-Almeida, Maria da Gloria;
    • Souza, Andreia Lamoglia;
    • Roma, Eric Henrique;
    • Azevedo, Marcos José;
    • Pereira-Silva, Fernanda Sant'Ana;
    • Pimentel, Luis Otavio;
    • Mendes, Marcelo Oliveira;
    • Garzoni, Luciana Ribeiro
    Publication type:
    Letter
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    New 1,2,3‐triazole‐based analogues of benznidazole for use against Trypanosoma cruzi infection: In vitro and in vivo evaluations.

    Published in:
    Chemical Biology & Drug Design, 2018, v. 92, n. 3, p. 1670, doi. 10.1111/cbdd.13333
    By:
    • Leite, Débora Inácio;
    • Fontes, Fábio De Vasconcellos;
    • Bastos, Monica Macedo;
    • Hoelz, Lucas Villas Boas;
    • Bianco, Maria Da Conceição Avelino Dias;
    • De Oliveira, Andressa Paula;
    • Da Silva, Patricia Bernardino;
    • Da Silva, Cristiane França;
    • Batista, Denise Da Gama Jean;
    • Da Gama, Aline Nefertiti Silva;
    • Peres, Raiza Brandão;
    • Villar, Jose Daniel Figueroa;
    • Soeiro, Maria De Nazaré Correia;
    • Boechat, Nubia
    Publication type:
    Article
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    Molecular description of α‐keto‐based inhibitors of cruzain with activity against Chagas disease combining 3D‐QSAR studies and molecular dynamics.

    Published in:
    Chemical Biology & Drug Design, 2018, v. 92, n. 2, p. 1475, doi. 10.1111/cbdd.13313
    By:
    • Saraiva, Ádria P. B.;
    • Miranda, Ricardo M.;
    • Valente, Renan P. P.;
    • Araújo, Jéssica O.;
    • Souza, Rutelene N. B.;
    • Costa, Clauber H. S.;
    • Oliveira, Amanda R. S.;
    • Almeida, Michell O.;
    • Figueiredo, Antonio F.;
    • Ferreira, João E. V.;
    • Alves, Cláudio Nahum;
    • Honorio, Kathia M.
    Publication type:
    Article
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    Novel Cruzain Inhibitors for the Treatment of Chagas' Disease.

    Published in:
    Chemical Biology & Drug Design, 2012, v. 80, n. 3, p. 398, doi. 10.1111/j.1747-0285.2012.01416.x
    By:
    • Rogers, Kathleen E;
    • Keränen, Henrik;
    • Durrant, Jacob D.;
    • Ratnam, Joseline;
    • Doak, Allison;
    • Arkin, Michelle R.;
    • McCammon, J. Andrew
    Publication type:
    Article
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