Works matching DE "CELLULAR signal transduction"

Results: 5000

Promoter demethylation of cerebellin 2 by ten-eleven translocation 3 contributes to peripheral sensitization in trigeminal neuropathic pain of mice.

Published in:

Journal of Headache & Pain, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s10194-025-02093-1

By:

Guan, Xin-Ying;
Yuan, Bao-Tong;
Li, Meng-Na;
Wang, Tian;
Zhu, Lin-Peng;
Song, Si-Yuan;
Ji, Lu-Lu;
Gao, Yong-Jing;
Ma, Ling-Jie

Publication type:

Article

Application of a metabolic network-based graph neural network for the identification of toxicant-induced perturbations Open Access.

Published in:

Toxicological Sciences, 2025, v. 206, n. 1, p. 19, doi. 10.1093/toxsci/kfaf065

By:

Yuan, Keji;
Nault, Rance

Publication type:

Article

Zwilch kinetochore protein affects the prognosis of cancer patients by participating in cell proliferation, enhancing cell communication, and reshaping the tumor microenvironment.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02981-7

By:

Yao, Long;
Liu, Lianpo;
Wu, Jinsong;
Huang, Yunlong;
Zhang, Renquan;
Zhang, Haoxue

Publication type:

Article

Pharmacology and metabolomic reveal Polysaccharides from polygonatum sibiricum ameliorate the diabetic osteoporosis in zebrafish.

Published in:

BMC Complementary Medicine & Therapies, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12906-025-04978-9

By:

Chen, Ziping;
Li, Na;
Zhou, Zhou;
Zhu, Lin;
Wang, Kai;
Chen, Shijin;
Gu, Quan;
Liu, Yujun;
Zhai, Kefeng;
Xu, Shuwen

Publication type:

Article

A piperidinyl indole derivative, potential complement factor B inhibitor, plays a renoprotective role in diabetic nephropathy.

Published in:

Diabetic Medicine, 2025, v. 42, n. 8, p. 1, doi. 10.1111/dme.70092

By:

Li, Zi‐Han;
Sun, Zi‐Jun;
Chang, Dong‐Yuan;
Zhao, Ming‐Hui;
Tang, Sydney C. W.;
Chen, Min

Publication type:

Article

LncRNA CASC2 mediates SOCS6 mRNA stabilization via U2AF2 recruitment to modulate macrophage polarisation in diabetic retinopathy.

Published in:

Diabetic Medicine, 2025, v. 42, n. 8, p. 1, doi. 10.1111/dme.70014

By:

Xiao, Fan;
Wu, Feipeng;
Zhong, Peipei;
Hu, Tian;
Luo, Rong

Publication type:

Article

An assembled molecular signaling map of interleukin-24: a resource to decipher its multifunctional immunoregulatory role in pathophysiological conditions.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1608101

By:

Aravind, Anjana;
Shaji, Vineetha;
Ahmed, Mukhtar;
Dagamajalu, Shobha;
Vijayakumar, Manavalan;
Prasad, Thottethodi Subrahmanya Keshava;
Raju, Rajesh

Publication type:

Article

Short-term exposure to a high-humidity environment triggers intestinal inflammation via AQP3.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1563602

By:

Song, Jian;
Huang, Xinhua;
Luo, Yi;
Li, Mengjun;
Ouyang, Yulin;
Liu, Wanli;
Pan, Hudan;
Luo, Huanhuan

Publication type:

Article

Pulmonary hypertension and associated heart failure: New insights on emerging signalling pathways.

Published in:

European Journal of Clinical Investigation, 2025, v. 55, n. 8, p. 1, doi. 10.1111/eci.70038

By:

Madonna, Rosalinda;
Montemaggi, Elisa

Publication type:

Article

Co-morbid mechanisms of intervertebral disc degeneration and osteoporosis: biomechanical coupling and molecular pathways synergistically driving degenerative lesions.

Published in:

Journal of Orthopaedic Surgery & Research, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13018-025-06075-6

By:

Ling, Zhifa;
Zeng, Xiaoli;
Luo, Qiaoyan;
Li, Xue;
Cui, Lijun

Publication type:

Article

Cartilage-protective effects of lopinavir/ritonavir: in vitro and in silico exploration of the HIF-1α/SOX9/IL-1β pathway.

Published in:

Journal of Orthopaedic Surgery & Research, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13018-025-06068-5

By:

Ozbek, Hanefi;
Yilmaz, Ibrahim;
Akyuz, Aslı;
Pehlivanoglu, Suray;
Sirin, Duygu Yasar;
Albayrak, Mehmet;
Yilmaz, Omer Faruk

Publication type:

Article

Single-nucleus profiling of the left ventricle of the mouse heart after chronic stress.

Published in:

Scientific Data, 2025, v. 12, n. 1, p. 1, doi. 10.1038/s41597-025-05556-x

By:

Li, Yaping;
Liu, Xia;
Zhang, Huaxing;
Wang, Qian;
Zhu, Yan;
Xu, Haibo;
Chen, Qinmin;
Xiang, Shulin;
Xiao, Han;
Qi, Qian;
Cong, Bin

Publication type:

Article

Modulating ion channels with nanobodies.

Published in:

Synthetic & Systems Biotechnology, 2025, v. 10, n. 2, p. 593, doi. 10.1016/j.synbio.2025.02.005

By:

Ali, Sher;
Suris, Ashley;
Yun Huang;
Yubin Zhou

Publication type:

Article

Molecular Networks Governing Plant Responses to Heat and Cold Stress.

Published in:

Plants (2223-7747), 2025, v. 14, n. 13, p. 2073, doi. 10.3390/plants14132073

By:

Zhang, Ran;
Yang, Lin;
Zhang, Huan;
Yang, Yingyu;
Wen, Lu;
Yin, Aoran;
Fu, Liwen

Publication type:

Article

Under Blue Light Treatment, OsCSN2 Regulates the Phenotype of Rice Seedlings Through the GA Signaling Pathway.

Published in:

Plants (2223-7747), 2025, v. 14, n. 13, p. 2015, doi. 10.3390/plants14132015

By:

Yu, Xinhai;
Jiao, Tongtong;
Liu, Changfeng;
Zhang, Hexin;
Liu, Yanxi;
Zhang, Chunyu;
Wu, Ming;
Guo, Liquan

Publication type:

Article

Advances in ERECTA Family Regulation of Female Gametophyte Development in Arabidopsis thaliana.

Published in:

Plants (2223-7747), 2025, v. 14, n. 13, p. 1900, doi. 10.3390/plants14131900

By:

Su, Han;
Jiang, Xiaohu;
Liu, Yanfen;
Cao, Zhuangyuan;
Liu, Ziqi;
Qin, Yuan;
He, Qing;
Cai, Hanyang

Publication type:

Article

Millet Quinic Acid Relieves Colitis by Regulating Gut Microbiota and Inhibiting MyD88/NF-κB Signaling Pathway.

Published in:

Foods, 2025, v. 14, n. 13, p. 2267, doi. 10.3390/foods14132267

By:

Li, Sen;
Zhang, Ze;
Luo, Lei;
Zhang, Yu;
Huang, Kai;
Guan, Xiao

Publication type:

Article

Purification, Structural Characterization, and Immunomodulatory Activity of an Exopolysaccharide from Acetilactobacillus jinshanensis BJ01 in Baijiu Fermentation Grains.

Published in:

Foods, 2025, v. 14, n. 13, p. 2162, doi. 10.3390/foods14132162

By:

Tian, Tian;
Wan, Bo;
Xiong, Ying;
Wang, Han;
An, Yuanyuan;
Gao, Ruijie;
Liu, Pulin;
Zhang, Mingchun;
Miao, Lihong;
Liao, Weifang

Publication type:

Article

Integrated Transcriptomic and Proteomic Analysis Reveals Differential Gene and Protein Expression and Signaling Pathways During a 20 Km Endurance Exercise and Recovery in Mongolian Horses.

Published in:

Animals (2076-2615), 2025, v. 15, n. 13, p. 1981, doi. 10.3390/ani15131981

By:

Zhang, Xinzhuang;
Liu, Yuanyi;
Ma, Wei;
Li, Lianhao;
Bai, Dongyi;
Dugarjaviin, Manglai

Publication type:

Article

LncRNA RWDD3 Facilitates Leydig Cell Steroidogenesis by Regulating the miR-1388-5p/NPY1R/cAMP Pathway in Yanshan Cashmere Goats.

Published in:

Animals (2076-2615), 2025, v. 15, n. 13, p. 1884, doi. 10.3390/ani15131884

By:

Chen, Meijing;
Yin, Xuejiao;
Duan, Chunhui;
Xie, Yuchun;
Ji, Chenghao;
Wang, Yong;
Liu, Yueqin;
Zhang, Yingjie

Publication type:

Article

Oncogenic Activity and Sorafenib Sensitivity of ARAF p.S214C Mutation in Lung Cancer.

Published in:

Cancers, 2025, v. 17, n. 13, p. 2246, doi. 10.3390/cancers17132246

By:

Lee, Carol;
Mu, Weixue;
Chen, Xi July;
Chan, Mandy Sze Man;
Chen, Zhishan;
Yeung, Sai Fung;
Chan, Helen Hoi Yin;
Chow, Sin Ting;
Ko, Ben Chi Bun;
Chan, David Wai;
Cho, William C.;
Lui, Vivian Wai Yan;
Tsui, Stephen Kwok Wing

Publication type:

Article

Peroxisomal Alterations in Prostate Cancer: Metabolic Shifts and Clinical Relevance.

Published in:

Cancers, 2025, v. 17, n. 13, p. 2243, doi. 10.3390/cancers17132243

By:

Hussein, Mohamed A. F.;
Lismont, Celien;
Li, Hongli;
Chai, Ruizhi;
Claessens, Frank;
Fransen, Marc

Publication type:

Article

The PI3K/Akt/mTOR Signaling Pathway in Triple-Negative Breast Cancer: A Resistance Pathway and a Prime Target for Targeted Therapies.

Published in:

Cancers, 2025, v. 17, n. 13, p. 2232, doi. 10.3390/cancers17132232

By:

Hassan, Ali;
Aubel, Corinne

Publication type:

Article

Current Landscape of Preclinical Models for Pediatric Gliomas: Clinical Implications and Future Directions.

Published in:

Cancers, 2025, v. 17, n. 13, p. 2221, doi. 10.3390/cancers17132221

By:

Faisal, Syed M.;
Yadav, Monika;
Gibson, Garrett R.;
Klinestiver, Adora T.;
Sorenson, Ryan M.;
Cantor, Evan;
Ghishan, Maria;
Prensner, John R.;
Franson, Andrea T.;
Ginn, Kevin F.;
Koschmann, Carl;
Yadav, Viveka Nand

Publication type:

Article

The Emerging Role of Extracellular Vesicle-Derived lncRNAs and circRNAs in Tumor and Mesenchymal Stem Cells: The Biological Functions and Potential for Clinical Application.

Published in:

Cancers, 2025, v. 17, n. 13, p. 2186, doi. 10.3390/cancers17132186

By:

Luo, Ya-Wen;
Liu, Chen-Guang;
Kirby, Jane Allyn;
Chu, Chen;
Zang, Dan;
Chen, Jun

Publication type:

Article

A Review of Emerging Immunotherapeutic Strategies for IDH-Mutant Glioma.

Published in:

Cancers, 2025, v. 17, n. 13, p. 2178, doi. 10.3390/cancers17132178

By:

Tazhibi, Masih;
Grewal, Eric P.;
Ramapriyan, Rishab;
Richardson, Leland G. K.;
Vandecandelaere, Gust;
Kalaw, Adrian;
Kotlarz, Parker;
Steuart, Samuel J.;
Sun, Jing;
Gaffey, Matthew;
Cahill, Daniel P.;
Miller, Julie J.;
Curry, William T.;
Choi, Bryan D.

Publication type:

Article

Dysregulated miRNA Expression and Its Association with Immune Checkpoints in Head and Neck Cancer.

Published in:

Cancers, 2025, v. 17, n. 13, p. 2169, doi. 10.3390/cancers17132169

By:

Shuaib, Mohd;
Saini, Diksha;
Sharma, Gargi;
Singh, Ishwar;
Gupta, Sanjay;
Kumar, Shashank;
Kumar, Pramod

Publication type:

Article

Diagnostic and Therapeutic Potential of Selected microRNAs in Colorectal Cancer: A Literature Review.

Published in:

Cancers, 2025, v. 17, n. 13, p. 2135, doi. 10.3390/cancers17132135

By:

Sychowski, Grzegorz;
Romanowicz, Hanna;
Ciesielski, Wojciech;
Hogendorf, Piotr;
Durczyński, Adam;
Smolarz, Beata

Publication type:

Article

Anti-Neoplastic Activity of Estrogen Receptor Beta in Chemoresistant Triple-Negative Breast Cancer.

Published in:

Cancers, 2025, v. 17, n. 13, p. 2132, doi. 10.3390/cancers17132132

By:

Wang, Xiyin;
Emch, Michael J.;
Goetz, Matthew P.;
Hawse, John R.

Publication type:

Article

Pilot Transcriptomic Profiling of Canine Oral Melanoma Reveals Conserved Oncogenic Pathways and Uncharacterized Molecular Signatures.

Published in:

Cancers, 2025, v. 17, n. 13, p. 2106, doi. 10.3390/cancers17132106

By:

Pérez-Santana, Carmen G.;
Rodríguez-Esparragón, Francisco;
Cazorla-Rivero, Sara E.;
Jiménez-Alonso, Ana A.;
Clavo, Bernardino;
González-Martín, Jesús M.;
Cánovas-Molina, Ángeles;
Bartolomé, Carmen;
Estupiñán, Lidia;
Rodríguez Grau-Bassas, Enrique

Publication type:

Article

Cancer Stem Cells Connecting to Immunotherapy: Key Insights, Challenges, and Potential Treatment Opportunities.

Published in:

Cancers, 2025, v. 17, n. 13, p. 2100, doi. 10.3390/cancers17132100

By:

Mathan, Sivapar V.;
Singh, Rana P.

Publication type:

Article

Lymphoproliferations in People Living with HIV: Oncogenic Pathways, Diagnostic Challenges, and New Therapeutic Opportunities.

Published in:

Cancers, 2025, v. 17, n. 13, p. 2088, doi. 10.3390/cancers17132088

By:

Dolcetti, Riccardo;
Vaccher, Emanuela;
Carbone, Antonino

Publication type:

Article

Bimodal Genomic Approach Predicting Semaphorin 7A (SEMA7A) as Prognostic Biomarker in Adrenocortical Carcinoma.

Published in:

Cancers, 2025, v. 17, n. 13, p. 2078, doi. 10.3390/cancers17132078

By:

Dhall, Anjali;
Taniyama, Daiki;
Elloumi, Fathi;
Luna, Augustin;
Varma, Sudhir;
Kumar, Suresh;
Escobedo, Lauren;
Sun, Yilun;
Aladjem, Mirit I.;
Redon, Christophe E.;
Roper, Nitin;
Reinhold, William C.;
Del Rivero, Jaydira;
Pommier, Yves

Publication type:

Article

TOPK Drives IL19-Mediated Crosstalk Between Cancer Cells and Fibroblasts to Promote Solar UV-Induced Skin Damage and Carcinogenesis.

Published in:

Cancers, 2025, v. 17, n. 13, p. 2067, doi. 10.3390/cancers17132067

By:

Khan, Asad U.;
Wang, Qiushi;
Roh, Eunmiri;
Dickinson, Sally E.;
Wondrak, Georg T.;
Curiel-Lewandowski, Clara;
Bode, Ann M.;
Zhang, Tianshun

Publication type:

Article

Modulation of Gut Microbial Composition by Lactobacillus delbrueckii subsp. lactis CKDB001 Supplementation in a High-Fat-Diet-Induced Obese Mice.

Published in:

Nutrients, 2025, v. 18, n. 13, p. 2251, doi. 10.3390/nu17132251

By:

Chu, Jaeryang;
No, Chae-Won;
Joung, Hyunchae;
Kim, Kyung Hwan;
Shin, Chang Hun;
Lee, Jisu;
Ha, Jung-Heun

Publication type:

Article

Dietary Polyphenols: Luteolin, Quercetin, and Apigenin as Potential Therapeutic Agents in the Treatment of Gliomas.

Published in:

Nutrients, 2025, v. 18, n. 13, p. 2202, doi. 10.3390/nu17132202

By:

Justyńska, Weronika;
Grabarczyk, Mikołaj;
Smolińska, Ewa;
Szychowska, Aleksandra;
Glabinski, Andrzej;
Szpakowski, Piotr

Publication type:

Article

Postbiotics Formulation and Therapeutic Effect in Inflammation: A Systematic Review.

Published in:

Nutrients, 2025, v. 18, n. 13, p. 2187, doi. 10.3390/nu17132187

By:

Zdybel, Kinga;
Śliwka, Angelika;
Polak-Berecka, Magdalena;
Polak, Paweł;
Waśko, Adam

Publication type:

Article

Preventive Effects of Medium-Chain Fatty Acid Intake on Muscle Atrophy.

Published in:

Nutrients, 2025, v. 18, n. 13, p. 2154, doi. 10.3390/nu17132154

By:

Sumi, Madoka;
Okamura, Takuro;
Matsuyama, Tomoyuki;
Miyoshi, Tomoki;
Nakajima, Hanako;
Nakanishi, Naoko;
Sasano, Ryoichi;
Hamaguchi, Masahide;
Fukui, Michiaki

Publication type:

Article

Voghera Sweet Pepper Regulates Cell Death Pathways in an Aging In Vitro Model.

Published in:

Nutrients, 2025, v. 18, n. 13, p. 2147, doi. 10.3390/nu17132147

By:

Gola, Federica;
Casali, Claudio;
Gaiaschi, Ludovica;
Roda, Elisa;
Milanesi, Gloria;
De Luca, Fabrizio;
Bottone, Maria Grazia

Publication type:

Article

High-Calorie Diet Exacerbates the Crosstalk Between Gestational Diabetes and Youth-Onset Diabetes in Female Offspring Through Disrupted Estrogen Signaling.

Published in:

Nutrients, 2025, v. 18, n. 13, p. 2128, doi. 10.3390/nu17132128

By:

Jia, Xinyu;
Cao, Xiangju;
Wang, Yuan;
Yang, Shuai;
Ji, Lixia

Publication type:

Article

Chestnut (Castanea crenata) Inner-Shell Extract Attenuates Barium-Chloride-Induced Injury and Denervation-Induced Atrophy in Skeletal Muscle of Mice.

Published in:

Nutrients, 2025, v. 18, n. 13, p. 2116, doi. 10.3390/nu17132116

By:

Kim, Jin-Hwa;
Chung, Eun-Hye;
Kim, Jeong-Won;
Jeong, Ji-Soo;
Kim, Chang-Yeop;
Lee, Su-Ha;
Ko, Je-Won;
Lim, Je-Oh;
Kim, Tae-Won

Publication type:

Article

Chronic Copper Overload Triggers Inflammation in Mesenteric PVAT Alongside Changes in Renin–Angiotensin System-Related Pathways.

Published in:

Nutrients, 2025, v. 18, n. 13, p. 2082, doi. 10.3390/nu17132082

By:

Mawandji, Nina Bruna de Souza;
Lisboa, Nayara Ariel da Silva;
Gomes, Karoline Neumann;
Vieira, Júlia Martins;
Simão, Jussara de Jesus;
Alonso-Vale, Maria Isabel;
Nunes, Karolini Zuqui;
Vassallo, Dalton Valentim;
Bolsoni-Lopes, Andressa

Publication type:

Article

Purple Potato Extract Suppresses Hypoxia-Induced Metabolic Reprogramming and Inhibits HIF-1α Signaling in Caco-2 Cells.

Published in:

Nutrients, 2025, v. 18, n. 13, p. 2079, doi. 10.3390/nu17132079

By:

Cui, Qiaorong;
Sun, Qi;
Iniguez, Alejandro Bravo;
Li, Xinrui;
Du, Min;
Zhu, Mei-Jun

Publication type:

Article

Epigallocatechin Gallate as a Potential Therapeutic Agent in Endometriosis: A Narrative Review.

Published in:

Nutrients, 2025, v. 18, n. 13, p. 2068, doi. 10.3390/nu17132068

By:

Markowska, Anna;
Kojs, Zbigniew;
Antoszczak, Michał;
Markowska, Janina;
Huczyński, Adam

Publication type:

Article

Pretreatment with Citrus reticulata 'Chachi' Polysaccharide Alleviates Alcohol-Induced Gastric Ulcer by Inhibiting NLRP3/ASC/Caspase-1 and Nrf2/HO-1 Signaling Pathways.

Published in:

Nutrients, 2025, v. 18, n. 13, p. 2062, doi. 10.3390/nu17132062

By:

Liang, Huosheng;
Liang, Yiyao;
Wu, Lipeng;
Lin, Long;
Yao, Yunan;
Deng, Jinji;
Xu, Jiepei;
Li, Huajian;
Gao, Fangfang;
Xing, Wenlong;
Yu, Meng;
Jia, Xuejing;
Wei, Minyan;
Li, Chuwen;
Zheng, Guodong

Publication type:

Article

A Comprehensive Perspective on the Biological Effects of Intermittent Fasting and Periodic Short-Term Fasting: A Promising Strategy for Optimizing Metabolic Health.

Published in:

Nutrients, 2025, v. 18, n. 13, p. 2061, doi. 10.3390/nu17132061

By:

Ciastek, Barbara;
Kapłon, Karolina;
Domaszewski, Przemysław

Publication type:

Article

Betulinic Acid Reduces Intestinal Inflammation and Enhances Intestinal Tight Junctions by Modulating the PPAR-γ/NF-κB Signaling Pathway in Intestinal Cells and Organoids.

Published in:

Nutrients, 2025, v. 18, n. 13, p. 2052, doi. 10.3390/nu17132052

By:

Zheng, Xu;
Cao, Zhen;
Wang, Mingqi;
Yuan, Ruqiang;
Han, Yinhe;
Li, Ang;
Wang, Xiuli

Publication type:

Article

Recent Advances in the Mechanisms and Applications of Astragalus Polysaccharides in Liver Cancer Treatment: An Overview.

Published in:

Molecules, 2025, v. 30, n. 13, p. 2792, doi. 10.3390/molecules30132792

By:

Wang, Wang;
Zhou, Hanting;
Sen, Akanksha;
Zhang, Pengxia;
Yuan, Linhong;
Zhou, Shaobo

Publication type:

Article

Tandem Mass Tags Quantitative Proteomics Reveal the Mechanism by Which Paeoniflorin Regulates the PI3K/AKT and BDNF/CREB Signaling Pathways to Inhibit Parkinson's Disease.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6498, doi. 10.3390/ijms26136498

By:

Feng, Zhen;
Jin, Chang;
Zhang, Yue;
Xue, Huiming;
Ai, Yongxing;
Wang, Jing;
Zheng, Meizhu;
Shi, Dongfang

Publication type:

Article

Spatial and Temporal Expression Patterns of EDA2R, PCDH9, and TRAF7 in Yotari (Dab1 −/−) Mice: Implicationsfor Understanding CAKUT Pathogenesis.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6421, doi. 10.3390/ijms26136421

By:

Komić, Jelena;
Kelam, Nela;
Racetin, Anita;
Filipović, Natalija;
Saraga-Babić, Mirna;
Ihara, Dai;
Katsuyama, Yu;
Vukojević, Katarina

Publication type:

Article