Works matching DE "CATHEPSIN D"

Results: 312

Cathepsin D mediates tachykinin-induced secondary follicle growth independent of the hypothalamic–pituitary–gonadal axis in mice.

Published in:

Frontiers in Endocrinology, 2025, p. 1, doi. 10.3389/fendo.2025.1621348

By:

Kawada, Tsuyoshi;
Aoyama, Masato;
Yasuda, Keiko;
Satake, Honoo

Publication type:

Article

Construction of epilepsy diagnosis model based on cell senescence-related genes and its potential mechanism.

Published in:

Frontiers in Neurology, 2025, p. 1, doi. 10.3389/fneur.2025.1555586

By:

Gong, Xiangyao;
Lu, Wei;
Xiao, Qihua;
Wang, Xiaopeng;
Cui, Chenchen;
Tang, Hai

Publication type:

Article

Resveratrol Attenuates CSF Markers of Neurodegeneration and Neuroinflammation in Individuals with Alzheimer's Disease.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5044, doi. 10.3390/ijms26115044

By:

Liu, Xiaoguang;
Baxley, Sean;
Hebron, Michaeline;
Turner, Raymond Scott;
Moussa, Charbel

Publication type:

Article

Hampered AMPK-ULK1 cascade in Alzheimer's disease (AD) instigates mitochondria dysfunctions and AD-related alterations which are alleviated by metformin.

Published in:

Alzheimer's Research & Therapy, 2025, v. 17, n. 1, p. 1, doi. 10.1186/s13195-025-01772-0

By:

Mary, Arnaud;
Barale, Samantha;
Eysert, Fanny;
Valverde, Audrey;
Lacas-Gervais, Sandra;
Bauer, Charlotte;
Eddarkaoui, Sabiha;
Buée, Luc;
Buée-Scherrer, Valérie;
Checler, Frédéric;
Chami, Mounia

Publication type:

Article

Recovery of Lysosomal Acidification and Autophagy Flux by Attapulgite Nanorods: Therapeutic Potential for Lysosomal Disorders.

Published in:

Biomolecules (2218-273X), 2025, v. 15, n. 5, p. 728, doi. 10.3390/biom15050728

By:

Hao, Yuanjing;
Fan, Xinru;
Huang, Xiaodan;
Li, Zhaoying;
Jing, Zhiyuan;
Zhang, Guilong;
Xu, Yuxue;
Zhang, Na;
Wei, Pengfei

Publication type:

Article

Cathepsin D-like enzyme from embryo of camel tick Hyalomma dromedarii (Acari: Ixodida).

Published in:

Persian Journal of Acarology, 2025, v. 14, n. 2, p. 209, doi. 10.22073/pja.v14i2.85470

By:

Helmy, Mohamed S.;
Masoud, Hassan M. M.;
Darwish, Doaa A.;
Abdel-Monsef, Mohamed M.;
Ibrahim, Mahmoud A.

Publication type:

Article

Proteomics-Based Exploration of the Hepatoprotective Mechanism of α-Lipoic Acid in Rats with Iron Overload-Induced Liver Injury.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4774, doi. 10.3390/ijms26104774

By:

Jiang, Shuxia;
Shu, Yujia;
Guo, Shihui;
Ni, Yingdong;
Zhao, Ruqian;
Shan, Hongli;
Ma, Wenqiang

Publication type:

Article

Osteosarcoma cells exhibit functional interactions with stromal cells, fostering a lung microenvironment conducive to the establishment of metastatic tumor cells.

Published in:

Molecular Biology Reports, 2024, v. 51, n. 1, p. 1, doi. 10.1007/s11033-024-09315-w

By:

Valenzuela Alvarez, Matías J. P.;
Gutierrez, Luciana M.;
Bayo, Juan M.;
Cantero, María J.;
Garcia, Mariana G.;
Bolontrade, Marcela F.

Publication type:

Article

Cathepsin D Expression and Gemcitabine Resistance in Pancreatic Cancer.

Published in:

JNCI Cancer Spectrum, 2020, v. 4, n. 1, p. N.PAG, doi. 10.1093/jncics/pkz060

By:

Mahajan, Ujjwal M;
Goni, Elisabetta;
Langhoff, Enno;
Li, Qi;
Costello, Eithne;
Greenhalf, William;
Kruger, Stephan;
Ormanns, Steffen;
Halloran, Christopher;
Ganeh, Paula;
Marron, Manuela;
Lämmerhirt, Felix;
Zhao, Yue;
Beyer, Georg;
Weiss, Frank-Ulrich;
Sendler, Matthias;
Bruns, Christiane J;
Kohlmann, Thomas;
Kirchner, Thomas;
Werner, Jens

Publication type:

Article

Thiophenes—Naturally Occurring Plant Metabolites: Biological Activities and In Silico Evaluation of Their Potential as Cathepsin D Inhibitors.

Published in:

Plants (2223-7747), 2022, v. 11, n. 4, p. 539, doi. 10.3390/plants11040539

By:

Ibrahim, Sabrin R. M.;
Omar, Abdelsattar M.;
Bagalagel, Alaa A.;
Diri, Reem M.;
Noor, Ahmad O.;
Almasri, Diena M.;
Mohamed, Shaimaa G. A.;
Mohamed, Gamal A.

Publication type:

Article

Late‐onset Krabbe disease presenting as spastic paraplegia – implications of GCase and CTSB/D.

Published in:

Annals of Clinical & Translational Neurology, 2024, v. 11, n. 7, p. 1715, doi. 10.1002/acn3.52078

By:

Mächtel, Rebecca;
Dobert, Jan‐Philipp;
Hehr, Ute;
Weiss, Alexander;
Kettwig, Matthias;
Laugwitz, Lucia;
Groeschel, Samuel;
Schmidt, Manuel;
Arnold, Philipp;
Regensburger, Martin;
Zunke, Friederike

Publication type:

Article

AGR2 is associated with gastric cancer progression and poor survival.

Published in:

Oncology Letters, 2016, v. 11, n. 3, p. 2075, doi. 10.3892/ol.2016.4160

By:

JUN ZHANG;
YONGMING JIN;
SHAONAN XU;
JIAYIN ZHENG;
QI ZHANG;
YUANYU WANG;
JINPING CHEN;
YAZENG HUANG;
XUJUN HE;
ZHONGSHENG ZHAO

Publication type:

Article

Cathepsin D serum and urine concentration in superficial and invasive transitional bladder cancer as determined by surface plasmon resonance imaging.

Published in:

Oncology Letters, 2014, v. 8, n. 3, p. 1323, doi. 10.3892/ol.2014.2250

By:

GORODKIEWICZ, EWA;
GUSZCZ, TOMASZ;
ROSZKOWSKA-JAKIMIEC, WIESLAWA;
KOZŁOWSKI, ROBERT

Publication type:

Article

Oxymatrine Attenuates Dopaminergic Neuronal Damage and Microglia-Mediated Neuroinflammation Through Cathepsin D-Dependent HMGB1/TLR4/NF-κB Pathway in Parkinson's Disease.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. 1, doi. 10.3389/fphar.2020.00776

By:

Gan, Ping;
Ding, Lidong;
Hang, Guihua;
Xia, Qiaofang;
Huang, Zhimei;
Ye, Xing;
Qian, Xiaojuan

Publication type:

Article

Comment on: 'Structural and functional differences in skin of colour'.

Published in:

Clinical & Experimental Dermatology, 2022, v. 47, n. 2, p. 407, doi. 10.1111/ced.14922

By:

Rawlings, A. V.;
Lane, M. E.;
Summers, B.;
Voegeli, R.

Publication type:

Article

Comprehensive Exploration of Target‐specific Ligands Using a Graph Convolution Neural Network.

Published in:

Molecular Informatics, 2020, v. 39, n. 1/2, p. N.PAG, doi. 10.1002/minf.201900095

By:

Miyazaki, Yu;
Ono, Naoaki;
Huang, Ming;
Altaf‐Ul‐Amin, Md.;
Kanaya, Shigehiko

Publication type:

Article

Amyloid Deposition and Advanced Age Fails to Induce Alzheimer's Type Progression in a Double Knock-In Mouse Model.

Published in:

Aging & Disease, 2012, v. 3, n. 2, p. 141

By:

Malthankar-Phatak, Gauri H.;
Yin-Guo Lin;
Giovannone, Nicholas;
Siman, Robert

Publication type:

Article

Cathepsin D Plays a Vital Role in Macrobrachium nipponense of Ovary Maturation: Identification, Characterization, and Function Analysis.

Published in:

Genes, 2022, v. 13, n. 8, p. 1495, doi. 10.3390/genes13081495

By:

Cheng, Dan;
Zhang, Wenyi;
Jiang, Sufei;
Xiong, Yiwei;
Jin, Shubo;
Pan, Fangyan;
Zhu, Junpeng;
Gong, Yongsheng;
Wu, Yan;
Qiao, Hui;
Fu, Hongtuo

Publication type:

Article

Cathepsin D Expression in Colorectal Cancer: From Proteomic Discovery through Validation Using Western Blotting, Immunohistochemistry, and Tissue Microarrays.

Published in:

International Journal of Proteomics, 2012, p. 1, doi. 10.1155/2012/245819

By:

Kirana, Chandra;
Shi, Hongjun;
Laing, Emma;
Hood, Kylie;
Miller, Rose;
Bethwaite, Peter;
Keating, John;
William Jordan, T.;
Hayes, Mark;
Stubbs, Richard

Publication type:

Article

Deciphering the Involvement of Chronic Inflammation in Osteoarthritis: Evaluation of Complement 3 and Cathepsin D in Osteoarthritic Patients--A Retrospective Case Study.

Published in:

Journal of Pharmacy & Bioallied Sciences, 2024, v. 16, p. S1221, doi. 10.4103/jpbs.jpbs_539_23

By:

Dhilip, Ashita;
Parameswari, R. P.

Publication type:

Article

Fluctuations in cell density alter protein markers of multiple cellular compartments, confounding experimental outcomes.

Published in:

PLoS ONE, 2019, v. 14, n. 2, p. 1, doi. 10.1371/journal.pone.0211727

By:

Trajkovic, Katarina;
Valdez, Clarissa;
Ysselstein, Daniel;
Krainc, Dimitri

Publication type:

Article

Protein regulation strategies of the mouse spleen in response to Babesia microti infection.

Published in:

Parasites & Vectors, 2021, v. 14, n. 1, p. 1, doi. 10.1186/s13071-020-04574-5

By:

Xue, Xiaomin;
Ren, Shuguang;
Yang, Xiaohong;
Masoudi, Abolfazl;
Hu, Yuhong;
Wang, Xiaoshuang;
Li, Hongxia;
Zhang, Xiaojing;
Wang, Minjing;
Wang, Hui;
Liu, Jingze

Publication type:

Article

Protein regulation strategies of the mouse spleen in response to Babesia microti infection.

Published in:

Parasites & Vectors, 2021, v. 14, n. 1, p. 1, doi. 10.1186/s13071-020-04574-5

By:

Xue, Xiaomin;
Ren, Shuguang;
Yang, Xiaohong;
Masoudi, Abolfazl;
Hu, Yuhong;
Wang, Xiaoshuang;
Li, Hongxia;
Zhang, Xiaojing;
Wang, Minjing;
Wang, Hui;
Liu, Jingze

Publication type:

Article

Protein regulation strategies of the mouse spleen in response to Babesia microti infection.

Published in:

Parasites & Vectors, 2021, v. 14, n. 1, p. 1, doi. 10.1186/s13071-020-04574-5

By:

Xue, Xiaomin;
Ren, Shuguang;
Yang, Xiaohong;
Masoudi, Abolfazl;
Hu, Yuhong;
Wang, Xiaoshuang;
Li, Hongxia;
Zhang, Xiaojing;
Wang, Minjing;
Wang, Hui;
Liu, Jingze

Publication type:

Article

Overexpression of Cathepsin E Interferes with Neuronal Differentiation of P19 Embryonal Teratocarcinoma Cells by Degradation of N-cadherin.

Published in:

Cellular & Molecular Neurobiology, 2017, v. 37, n. 3, p. 437, doi. 10.1007/s10571-016-0376-x

By:

Harada, Yuka;
Takayama, Fumiko;
Tanabe, Kazunari;
Ni, Junjun;
Hayashi, Yoshinori;
Yamamoto, Kenji;
Wu, Zhou;
Nakanishi, Hiroshi

Publication type:

Article

Zinc enhances autophagic flux and lysosomal function through transcription factor EB activation and V-ATPase assembly.

Published in:

Frontiers in Cellular Neuroscience, 2022, v. 16, p. 1, doi. 10.3389/fncel.2022.895750

By:

Ki-Ryeong Kim;
Sang Eun Park;
Ji-Ye Hong;
Jae-Young Koh;
Dong-Hyung Cho;
Jung Jin Hwang;
Yang-Hee Kim

Publication type:

Article

Cathepsins and neurological diseases: a Mendelian randomization study.

Published in:

Frontiers in Neuroscience, 2024, p. 1, doi. 10.3389/fnins.2024.1454369

By:

Haitao Sun;
Qingqing Tang;
Xue Yan;
Wanying Xie;
Yueshan Xu;
Weimin Zhang

Publication type:

Article

Relation between serum cathepsin D levels and endothelial dysfunction in patients with chronic kidney disease.

Published in:

Nefrologia, 2015, v. 35, n. 1, p. 72, doi. 10.3265/Nefrologia.pre2014.Oct.12609

By:

Ozkayar, Nihal;
Piskinpasa, Serhan;
Akyel, Fatma;
Turgut, Didem;
Bulut, Mesudiye;
Turhan, Turan;
Dede, Fatih

Publication type:

Article

Functionally distinct pericyte subsets differently regulate amyloid‐β deposition in patients with Alzheimer's disease.

Published in:

Brain Pathology, 2025, v. 35, n. 2, p. 1, doi. 10.1111/bpa.13282

By:

Bohannon, Diana G.;
Long, Danielle;
Okhravi, Hamid R.;
Lee, Sunhee C.;
De Jesus, Christopher Lawrence;
Neubert, Thomas A.;
Rostagno, Agueda A.;
Ghiso, Jorge A.;
Kim, Woong‐Ki

Publication type:

Article

Lysosomal cathepsin D is upregulated in Alzheimer's disease neocortex and may be a marker for neurofibrillary degeneration.

Published in:

Brain Pathology, 2019, v. 29, n. 1, p. 63, doi. 10.1111/bpa.12631

By:

Chai, Yuek Ling;
Chong, Joyce R.;
Weng, Jiaju;
Howlett, David;
Halsey, Andrea;
Lee, Jasinda H.;
Attems, Johannes;
Aarsland, Dag;
Francis, Paul T.;
Chen, Christopher P.;
Lai, Mitchell K.P.

Publication type:

Article

α-Synuclein Degradation in Brain Pericytes Is Mediated via Akt, ERK, and p38 MAPK Signaling Pathways.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 4, p. 1615, doi. 10.3390/ijms26041615

By:

Yokoya, Miki;
Takata, Fuyuko;
Iwao, Takuro;
Matsumoto, Junichi;
Tanaka, Yasuyoshi;
Aridome, Hisataka;
Yasunaga, Miho;
Mizoguchi, Junko;
Sano, Kazunori;
Dohgu, Shinya

Publication type:

Article

The E3 ubiquitin ligase TRIM31 attenuates NLRP3 inflammasome activation in Helicobacter pylori-associated gastritis by regulating ROS and autophagy.

Published in:

Cell Communication & Signaling, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12964-022-00954-9

By:

Yu, Qiao;
Shi, Huiying;
Ding, Zhen;
Wang, Zhe;
Yao, Hailing;
Lin, Rong

Publication type:

Article

Synergistic anticancer effects of combined γ-tocotrienol and oridonin treatment is associated with the induction of autophagy.

Published in:

Molecular & Cellular Biochemistry, 2015, v. 408, n. 1/2, p. 123, doi. 10.1007/s11010-015-2488-x

By:

Tiwari, Roshan;
Sylvester, Paul;
Parajuli, Parash

Publication type:

Article

Advanced glycation end products promote proliferation and suppress autophagy via reduction of Cathepsin D in rat vascular smooth muscle cells.

Published in:

Molecular & Cellular Biochemistry, 2015, v. 403, n. 1/2, p. 73, doi. 10.1007/s11010-015-2338-x

By:

Ma, Mingfeng;
Guo, Xiaofan;
Chang, Ye;
Li, Chao;
Meng, Xin;
Li, Si;
Du, Zhen-Xian;
Wang, Hua-Qin;
Sun, Yingxian

Publication type:

Article

Autophagic- and Lysosomal-Related Biomarkers for Parkinson's Disease: Lights and Shadows.

Published in:

Cells (2073-4409), 2019, v. 8, n. 11, p. 1317, doi. 10.3390/cells8111317

By:

Xicoy, Helena;
Peñuelas, Núria;
Vila, Miquel;
Laguna, Ariadna

Publication type:

Article

Antiretroviral-Mediated Microglial Activation Involves Dysregulated Autophagy and Lysosomal Dysfunction.

Published in:

Cells (2073-4409), 2019, v. 8, n. 10, p. 1168, doi. 10.3390/cells8101168

By:

Tripathi, Ashutosh;
Thangaraj, Annadurai;
Chivero, Ernest T.;
Periyasamy, Palsamy;
Callen, Shannon;
Burkovetskaya, Maria E.;
Guo, Ming-Lei;
Buch, Shilpa

Publication type:

Article

Alterations of Plasma Galectin-3 and C3 Levels in Patients with Parkinson's Disease.

Published in:

Brain Sciences (2076-3425), 2021, v. 11, n. 11, p. 1515, doi. 10.3390/brainsci11111515

By:

Wu, Hsiu-Chuan;
Chang, Kuo-Hsuan;
Chiang, Mu-Chun;
Chen, Chiung-Mei

Publication type:

Article

Neuroprotective effect of dexmedetomidine on autophagy in mice administered intracerebroventricular injections of Aβ25-35.

Published in:

Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1184776

By:

Youn Young Lee;
Jong In Han;
Kyung Eun Lee;
Sooyoung Cho;
Eun Cheng Suh

Publication type:

Article

Significance of cytosolic cathepsin D in Alzheimer's disease pathology: Protective cellular effects of PLGA nanoparticles against β‐amyloid‐toxicity.

Published in:

Neuropathology & Applied Neurobiology, 2020, v. 46, n. 7, p. 686, doi. 10.1111/nan.12647

By:

Wang, Y.;
Wu, Q.;
Anand, B. G.;
Karthivashan, G.;
Phukan, G.;
Yang, J.;
Thinakaran, G.;
Westaway, D.;
Kar, S.

Publication type:

Article

Exploring the putative role of kallikrein‐6, calpain‐1 and cathepsin‐D in the proteolytic degradation of α‐synuclein in multiple system atrophy.

Published in:

Neuropathology & Applied Neurobiology, 2019, v. 45, n. 4, p. 347, doi. 10.1111/nan.12512

By:

Kiely, A. P.;
Miners, J. S.;
Courtney, R.;
Strand, C.;
Love, S.;
Holton, J. L.

Publication type:

Article

The role of lysosomes and autophagosomes in frontotemporal lobar degeneration.

Published in:

Neuropathology & Applied Neurobiology, 2019, v. 45, n. 3, p. 244, doi. 10.1111/nan.12500

By:

Bain, H. D. C.;
Davidson, Y. S.;
Robinson, A. C.;
Mann, D. M. A.;
Snowden, J. S.;
Ryan, S.;
Rollinson, S.;
Pickering‐Brown, S.;
Richardson, A.;
Jones, M.

Publication type:

Article

EXPOSURE TO NANOPARTICLES OF MAGNETITE FE3 O4 IN THREE DIFFERENT DOSES AND THEIR INFLUENCE ON SELECTED RESPIRATORY PARAMETERS OF BRONCHOALVEOLAR LAVAGE AFTER INTRAVENOUS INSTILLATION.

Published in:

Central European Journal of Public Health, 2023, v. 31, n. 4, p. 265, doi. 10.21101/cejph.a7739

By:

Hurbánková, Marta;
Volkovová, Katarína;
Černá, Silvia;
Wimmerová, Soňa;
Moricová, Štefánia

Publication type:

Article

Citreoviridin Induces Autophagy-Dependent Apoptosis through Lysosomal-Mitochondrial Axis in Human Liver HepG2 Cells.

Published in:

Toxins, 2015, v. 7, n. 8, p. 3030, doi. 10.3390/toxins7083030

By:

Yuexia Wang;
Yanan Liu;
Xiaofang Liu;
Liping Jiang;
Guang Yang;
Xiance Sun;
Chengyan Geng;
Qiujuan Li;
Xiaofeng Yao;
Min Chen

Publication type:

Article

GSK-3 and lysosomes meet in Alzheimer's disease.

Published in:

Communicative & Integrative Biology, 2013, v. 6, n. 5, p. 1, doi. 10.4161/cib.25179

By:

Avrahami, Limor;
Eldar-Finkelman, Hagit

Publication type:

Article

The Role of DmCatD, a Cathepsin D-Like Peptidase, and Acid Phosphatase in the Process of Follicular Atresia in Dipetalogaster maxima (Hemiptera: Reduviidae), a Vector of Chagas' Disease.

Published in:

PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0130144

By:

Leyria, Jimena;
Fruttero, Leonardo L.;
Nazar, Magalí;
Canavoso, Lilián E.

Publication type:

Article

New Roles of Glycosaminoglycans in α-Synuclein Aggregation in a Cellular Model of Parkinson Disease.

Published in:

PLoS ONE, 2015, v. 10, n. 1, p. 1, doi. 10.1371/journal.pone.0116641

By:

Lehri-Boufala, Sonia;
Ouidja, Mohand-Ouidir;
Barbier-Chassefière, Véronique;
Hénault, Emilie;
Raisman-Vozari, Rita;
Garrigue-Antar, Laure;
Papy-Garcia, Dulce;
Morin, Christophe

Publication type:

Article

Cleavage of Histone 3 by Cathepsin D in the Involuting Mammary Gland.

Published in:

PLoS ONE, 2014, v. 9, n. 7, p. 1, doi. 10.1371/journal.pone.0103230

By:

Khalkhali-Ellis, Zhila;
Goossens, William;
Margaryan, Naira V.;
Hendrix, Mary J. C.

Publication type:

Article

Factors Influencing the Measurement of Lysosomal Enzymes Activity in Human Cerebrospinal Fluid.

Published in:

PLoS ONE, 2014, v. 9, n. 7, p. 1, doi. 10.1371/journal.pone.0101453

By:

Persichetti, Emanuele;
Chiasserini, Davide;
Parnetti, Lucilla;
Eusebi, Paolo;
Paciotti, Silvia;
De Carlo, Claudia;
Codini, Michela;
Tambasco, Nicola;
Rossi, Aroldo;
Agnaf, Omar M. El.;
Calabresi, Paolo;
Beccari, Tommaso

Publication type:

Article

A Prognostic Model for Triple-Negative Breast Cancer Patients Based on Node Status, Cathepsin-D and Ki-67 Index.

Published in:

PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0083081

By:

Huang, Liang;
Liu, Zhebin;
Chen, Sheng;
Liu, Yin;
Shao, Zhiming

Publication type:

Article

Proteolytic Characteristics of Cathepsin D Related to the Recognition and Cleavage of Its Target Proteins.

Published in:

PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0065733

By:

Sun, Huiying;
Lou, Xiaomin;
Shan, Qiang;
Zhang, Ju;
Zhu, Xu;
Zhang, Jia;
Wang, Yang;
Xie, Yingying;
Xu, Ningzhi;
Liu, Siqi

Publication type:

Article