Works about CASPASES regulation

Results: 116

Host response: Connecting the dots in inflammasome activation.

Published in:

Nature Reviews Microbiology, 2012, v. 10, n. 9, p. 596, doi. 10.1038/nrmicro2866

By:

Jermy, Andrew

Publication type:

Article

Specific signaling pathways mediated programmed cell death in tumor microenvironment and target therapies.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02592-2

By:

Sun, Chengpeng;
Gui, Jiawei;
Sheng, Yilei;
Huang, Le;
Zhu, Xingen;
Huang, Kai

Publication type:

Article

Sex Differences in Mechanisms and Outcome of Neonatal Hypoxia-Ischemia in Rodent Models: Implications for Sex-Specific Neuroprotection in Clinical Neonatal Practice.

Published in:

Neurology Research International, 2012, p. 1, doi. 10.1155/2012/867531

By:

Hill, Courtney A.;
Fitch, R. Holly

Publication type:

Article

Caspase-9 was involved in cell apoptosis in human dental pulp stem cells from deciduous teeth.

Published in:

Molecular Medicine Reports, 2018, v. 18, n. 1, p. 1067, doi. 10.3892/mmr.2018.9046

By:

Qian, Hong;
Huang, Qun;
Chen, Yu-Xiang;
Liu, Qiong;
Fang, Jing-Xian;
Ye, Man-Wen

Publication type:

Article

PYGB siRNA inhibits the cell proliferation of human osteosarcoma cell lines.

Published in:

Molecular Medicine Reports, 2018, v. 18, n. 1, p. 715, doi. 10.3892/mmr.2018.9022

By:

Zhang, Shuwei;
Zhou, Yichi;
Zha, Yuanyu;
Yang, Yang;
Wang, Linlong;
Li, Jingfeng;
Jin, Wei

Publication type:

Article

Oxymatrine protects against sepsis-induced myocardial injury via inhibition of the TNF-α/p38-MAPK/caspase-3 signaling pathway.

Published in:

Molecular Medicine Reports, 2016, v. 14, n. 1, p. 551, doi. 10.3892/mmr.2016.5250

By:

MINGHAO ZHANG;
XIUYU WANG;
BIN BAI;
RUI ZHANG;
YUNHONG LI;
YIN WANG

Publication type:

Article

Expression of cluster of differentiation-95 and relevant signaling molecules in liver cancer.

Published in:

Molecular Medicine Reports, 2015, v. 11, n. 5, p. 3375, doi. 10.3892/mmr.2014.3129

By:

XUMING WANG;
KANGLAI WEI;
QIONGGUANG ZHANG;
SIEN ZENG;
JING LIN;
LI QIAO;
LIJIANG LIU

Publication type:

Article

Inhibition of autophagy enhances the effects of the AKT inhibitor MK-2206 when combined with paclitaxel and carboplatin in BRAF wild-type melanoma.

Published in:

Pigment Cell & Melanoma Research, 2014, v. 27, n. 3, p. 465, doi. 10.1111/pcmr.12227

By:

Rebecca, Vito W.;
Massaro, Renato R.;
Fedorenko, Inna V.;
Sondak, Vernon K.;
Anderson, Alexander R. A.;
Kim, Eunjung;
Amaravadi, Ravi K.;
Maria ‐ Engler, Silvya S.;
Messina, Jane L.;
Gibney, Geoffrey T.;
Kudchadkar, Ragini R.;
Smalley, Keiran S. M.

Publication type:

Article

The Increased Activity of Caspases 8 and 9 Induced By Antiphospholipid Antibodies Activates Caspase 3 to Induce Trophoblast Death in Cultured Placental Explants: A Possible Mechanism to the Pathogenesis of Preeclampsia.

Published in:: 2018
Publication type:: Abstract

Smac127 Has Proapoptotic and Anti-Inflammatory Effects on Rheumatoid Arthritis Fibroblast-Like Synoviocytes.

Published in:

Mediators of Inflammation, 2016, p. 1, doi. 10.1155/2016/6905678

By:

Lattuada, D.;
Gualtierotti, R.;
Crotta, K.;
Seneci, P.;
Ingegnoli, F.;
Corradini, C.;
Viganò, R.;
Marelli, O.;
Casnici, C.

Publication type:

Article

Caspase-3 Deficiency Results in Disrupted Synaptic Homeostasis and Impaired Attention Control.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 5, p. 2118, doi. 10.1523/JNEUROSCI.3280-14.2015

By:

Shih-Ching Lo;
Yuanyuan Wang;
Weber, Martin;
Larson, Jessica L.;
Scearce-Levie, Kimberly;
Sheng, Morgan

Publication type:

Article

Inflammasome-Induced IL-1β Secretion in Microglia Is Characterized by Delayed Kinetics and Is Only Partially Dependent on Inflammatory Caspases.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 2, p. 678, doi. 10.1523/JNEUROSCI.2510-14.2015

By:

Burm, Saskia M.;
Zuiderwijk-Sick, Ella A.;
't Jong, Anke E.J.;
van der Putten, Céline;
Veth, Jennifer;
Kondova, Ivanela;
Bajramovic, Jeffrey J.

Publication type:

Article

Differential response of head and neck cancer cell lines to TRAIL or Smac mimetics is associated with the cellular levels and activity of caspase-8 and caspase-10.

Published in:

British Journal of Cancer, 2014, v. 111, n. 10, p. 1955, doi. 10.1038/bjc.2014.521

By:

Raulf, N;
El-Attar, R;
Odell, E;
Tavassoli, M;
Kulms, D;
Lecis, D;
Delia, D;
Walczak, H;
Papenfuss, K

Publication type:

Article

Effects of X-ray on the metacestodes of Echinococcus granulosus in vitro.

Published in:

2017

By:

Rui Mao;
Ge Wu;
Hui Wang;
Pengfei Lu;
Jun Li;
Haitao Li;
Aimudula Ainiwaer;
Yiwei Bai;
Mingyang Shu;
Yongxing Bao;
Wenbao Zhang;
Mao, Rui;
Wu, Ge;
Wang, Hui;
Lu, Pengfei;
Li, Jun;
Li, Haitao;
Ainiwaer, Aimudula;
Bai, Yiwei;
Shu, Mingyang

Publication type:

journal article

NecroX-5 suppresses sodium nitroprusside-induced cardiac cell death through inhibition of JNK and caspase-3 activation.

Published in:

Cell Biology International, 2014, v. 38, n. 6, p. 702, doi. 10.1002/cbin.10242

By:

Lee, Sung Ryul;
Lee, Seon Joong;
Kim, Soon Ha;
Ko, Kyung Soo;
Rhee, Byoung Doo;
Xu, Zhelong;
Kim, Nari;
Han, Jin

Publication type:

Article

Paeoniflorin inhibits nucleus pulposus cell apoptosis by regulating the expression of Bcl-2 family proteins and caspase-9 in a rabbit model of intervertebral disc degeneration.

Published in:

Experimental & Therapeutic Medicine, 2015, v. 10, n. 1, p. 257, doi. 10.3892/etm.2015.2501

By:

LIJUN SHI;
HONGLIN TENG;
MINYU ZHU;
CHI LI;
KELUN HUANG;
BI CHEN;
YUSEN DAI;
JING WANG

Publication type:

Article

Data-Driven Mathematical Model of Apoptosis Regulation in Memory Plasma Cells.

Published in:

Cells (2073-4409), 2022, v. 11, n. 9, p. N.PAG, doi. 10.3390/cells11091547

By:

Burt, Philipp;
Cornelis, Rebecca;
Geißler, Gustav;
Hahne, Stefanie;
Radbruch, Andreas;
Chang, Hyun-Dong;
Thurley, Kevin

Publication type:

Article

Inhibitory Effects of Black Garlic Extracting Solution on the Growth of Mice Colon Cancer Ht-29.

Published in:

Medicinal Plant, 2015, v. 6, n. 9/10, p. 4

By:

Chunfeng YU;
Aihua HOU;
Yuejun MU;
Wei LIU;
Laifu LIU

Publication type:

Article

Heat-killed probiotic bacteria induce apoptosis of HT-29 human colon adenocarcinoma cell line via the regulation of Bax/Bcl2 and caspases pathway.

Published in:

Human & Experimental Toxicology, 2019, v. 38, n. 9, p. 1069, doi. 10.1177/0960327119851255

By:

Karimi Ardestani, S;
Tafvizi, F;
Tajabadi Ebrahimi, M

Publication type:

Article

Manganese activates caspase-9-dependent apoptosis in human bronchial epithelial cells.

Published in:

Human & Experimental Toxicology, 2013, v. 32, n. 11, p. 1155, doi. 10.1177/0960327112470272

By:

Zhang, L;
Sang, H;
Liu, Y;
Li, J

Publication type:

Article

Theaflavin-3,3'-digallate triggers apoptosis in osteosarcoma cells via the caspase pathway.

Published in:

Journal of Cancer, 2025, v. 16, n. 8, p. 2567, doi. 10.7150/jca.111718

By:

Yat-Yin Law;
Yi-Hsien Hsieh;
Yih-Shou Hsieh;
Yi-Hsun Lee;
Chia-Ling Tang;
Chia-Yi Lee;
Shun-Fa Yang;
Shu-Chen Chu;
Pei-Ni Chen

Publication type:

Article

Uric acid induces caspase-1 activation, IL-1β secretion and P2X7 receptor dependent proliferation in primary human lymphocytes.

Published in:

Hippokratia, 2013, v. 17, n. 2, p. 141

By:

Eleftheriadis, T.;
Pissas, G.;
Karioti, A.;
Antoniadi, G.;
Golfinopoulos, S.;
Liakopoulos, V.;
Mamara, A.;
Speletas, M. M.;
Koukoulis, G.;
Stefanidis, I.

Publication type:

Article

Synthetic immunostimulatory glycans interference with host cell apoptosis upon of Toxoplasma gondii infection, in vitro.

Published in:

Iraqi Journal of Veterinary Sciences, 2017, v. 31, n. 1, p. 43, doi. 10.33899/ijvs.2017.126709

By:

Eassa, S. H.

Publication type:

Article

NLRP3 inflammasome activation is associated with proliferative diabetic retinopathy.

Published in:

Acta Ophthalmologica (1755375X), 2017, v. 95, n. 8, p. 803, doi. 10.1111/aos.13427

By:

Loukovaara, Sirpa;
Piippo, Niina;
Kinnunen, Kati;
Hytti, Maria;
Kaarniranta, Kai;
Kauppinen, Anu

Publication type:

Article

Different effects of anesthetic isoflurane on caspase-3 activation and cytosol cytochrome c levels between mice neural progenitor cells and neurons.

Published in:

Frontiers in Cellular Neuroscience, 2014, v. 8, p. 1, doi. 10.3389/fncel.2014.00014

By:

Yiying Zhang;
Chuxiong Pan;
Xu Wu;
Yuanlin Dong;
Culley, Deborah J.;
Crosby, Gregory;
Tianzuo Li;
Zhongcong Xie

Publication type:

Article

The nuclear splicing factor RNA binding motif 5 promotes caspase activation in human neuronal cells, and increases after traumatic brain injury in mice.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2015, v. 35, n. 4, p. 655, doi. 10.1038/jcbfm.2014.242

By:

Jackson, Travis C;
Du, Lina;
Janesko-Feldman, Keri;
Vagni, Vincent A;
Dezfulian, Cameron;
Poloyac, Samuel M;
Jackson, Edwin K;
Clark, Robert SB;
Kochanek, Patrick M

Publication type:

Article

Induction of Caspase-2 Activation by a DNA Enzyme Evokes Tumor Cell Apoptosis.

Published in:

DNA & Cell Biology, 2012, v. 31, n. 1, p. 1, doi. 10.1089/dna.2011.1323

By:

Kim, Soo-Hyun;
Dass, Crispin R.

Publication type:

Article

Multifaceted roles for BCL3 in cancer: a proto-oncogene comes of age.

Published in:

Molecular Cancer, 2024, v. 23, n. 1, p. 1, doi. 10.1186/s12943-023-01922-8

By:

Seaton, Gillian;
Smith, Hannah;
Brancale, Andrea;
Westwell, Andrew D.;
Clarkson, Richard

Publication type:

Article

Proteinase 3-dependent caspase-3 cleavage modulates neutrophil death and inflammation.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 10, p. 4445, doi. 10.1172/JCI76246

By:

Loison, Fabien;
Haiyan Zhu;
Kutay Karatepe;
Anongnard Kasorn;
Peng Liu;
Keqiang Ye;
Jiaxi Zhou;
Shannan Cao;
Haiyan Gong;
Jenne, Dieter E.;
Remold-O'Donnell, Eileen;
Yuanfu Xu;
Hongbo R. Luo

Publication type:

Article

Improving Topical Non-Melanoma Skin Cancer Treatment: In vitro Efficacy of a Novel Guanosine-Analog Phosphonate.

Published in:

Skin Pharmacology & Physiology, 2014, v. 27, n. 4, p. 173, doi. 10.1159/000354118

By:

ali-von Laue, C.;
Zoschke, C.;
Do, N.;
Lehnen, D.;
Küchler, S.;
Mehnert, W.;
Blaschke, T.;
Kramer, K.D.;
Plendl, J.;
Weindl, G.;
Korting, H.C.;
Hoeller Obrigkeit, D.;
Merk, H.-F.;
Schäfer-Korting, M.

Publication type:

Article

Equilibria and stability of a class of positive feedback loops.

Published in:

Journal of Mathematical Biology, 2014, v. 68, n. 3, p. 609, doi. 10.1007/s00285-013-0644-z

By:

López-Caamal, Fernando;
Middleton, Richard;
Huber, Heinrich

Publication type:

Article

Synthesis and in vitro evaluation of 4-substituted furano[3,2-c] tetrahydroquinolines as potential anti-cancer agents.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2016, v. 31, n. 5, p. 853, doi. 10.3109/14756366.2015.1064120

By:

Chen, Can;
Zingales, Sarah;
Wang, Ting;
Yuan, Mingyong;
Wang, Dan;
Cai, Lulu;
Jiang, Qinglin

Publication type:

Article

Caspase-8 polymorphisms result in reduced Alemtuzumab-induced T-cell apoptosis and worse survival after transplantation.

Published in:

Bone Marrow Transplantation, 2015, v. 50, n. 2, p. 237, doi. 10.1038/bmt.2014.238

By:

Shaw, B E;
Lee, F;
Krishnamurthy, S;
Byrne, J L;
Seedhouse, C;
Mayor, N P;
Maldonado-Torres, H;
Saudemont, A;
Marsh, S G E;
Madrigal, J A;
Russell, N H

Publication type:

Article

Cytotoxicity, Regulation of Apoptotic and Anti-apoptotic Gene Expression by IL-27 in MCF-7 and MDA-MB-231 Breast Cancer Cell Lines.

Published in:

Malaysian Journal of Health Sciences / Jurnal Sains Kesihatan Malaysia, 2018, v. 16, p. 15, doi. 10.17576/JSKM-2018-03

By:

BOON, YAP WEI;
NADARAJAH, SHAKTYPREYA;
SHIDIK, NADIAH;
ALITHEEN, NOORJAHAN BANU MOHAMMED

Publication type:

Article

When Beauty Is Skin Deep: Regulation of the Wound Response by Caspase-8, RIPK3, and the Inflammasome.

Published in:

Journal of Investigative Dermatology, 2015, v. 135, n. 8, p. 1936, doi. 10.1038/jid.2015.185

By:

Vince, James E

Publication type:

Article

Regulation and Function of the Caspase-1 in an Inflammatory Microenvironment.

Published in:

Journal of Investigative Dermatology, 2015, v. 135, n. 8, p. 2012, doi. 10.1038/jid.2015.119

By:

Lee, Dai-Jen;
Du, Fei;
Chen, Shih-Wei;
Nakasaki, Manando;
Rana, Isha;
Shih, Vincent F S;
Hoffmann, Alexander;
Jamora, Colin

Publication type:

Article

Filaggrin Degradation by Caspase-14 Is Required for UVB Photoprotection but Does Not Influence Allergic Sensitization in a Mouse Model of Atopic Dermatitis.

Published in:

Journal of Investigative Dermatology, 2012, v. 132, n. 12, p. 2857, doi. 10.1038/jid.2012.236

By:

Devos, Michael;
Prawitt, Janne;
Staumont-Salle, Delphine;
Hoste, Esther;
Fleury, Sebastién;
Bouchaert, Emmanuel;
Gilbert, Barbara;
Lippens, Saskia;
Vandenabeele, Peter;
Dombrowicz, David;
Declercq, Wim

Publication type:

Article

Apigenin Protects Endothelial Cells from Lipopolysaccharide (LPS)-Induced Inflammation by Decreasing Caspase-3 Activation and Modulating Mitochondrial Function.

Published in:

International Journal of Molecular Sciences, 2013, v. 14, n. 9, p. 17664, doi. 10.3390/ijms140917664

By:

Duarte, Silvia;
Arango, Daniel;
Parihar, Arti;
Hamel, Patrice;
Yasmeen, Rumana;
Doseff, Andrea I.

Publication type:

Article

Harmine, a dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) inhibitor induces caspase-mediated apoptosis in neuroblastoma.

Published in:

Cancer Cell International, 2018, v. 18, n. 1, p. N.PAG, doi. 10.1186/s12935-018-0574-3

By:

Uhl, Katie L.;
Schultz, Chad R.;
Geerts, Dirk;
Bachmann, André S.

Publication type:

Article

Caspase-11-dependent pyroptosis of lung epithelial cells protects from melioidosis while caspase-1 mediates macrophage pyroptosis and production of IL-18.

Published in:

PLoS Pathogens, 2018, v. 14, n. 5, p. 1, doi. 10.1371/journal.ppat.1007105

By:

Wang, Jinyong;
Sahoo, Manoranjan;
Lantier, Louis;
Warawa, Jonathan;
Cordero, Hector;
Deobald, Kelly;
Re, Fabio

Publication type:

Article

How does caspases regulation play role in cell decisions? apoptosis and beyond.

Published in:

Molecular & Cellular Biochemistry, 2024, v. 479, n. 7, p. 1599, doi. 10.1007/s11010-023-04870-5

By:

Ghorbani, Negar;
Yaghubi, Roham;
Davoodi, Jamshid;
Pahlavan, Sara

Publication type:

Article

NLRC4 regulates caspase-1 and IL-1beta production in a CD11blowLy6Glow population of cells required for resistance to Pseudomonas aeruginosa keratitis.

Published in:

PLoS ONE, 2017, v. 12, n. 9, p. 1, doi. 10.1371/journal.pone.0185718

By:

McClellan, Sharon A.;
Jerome, Andrew;
Suvas, Susmit;
Hazlett, Linda D.

Publication type:

Article

The anti-inflammatory effects of acetaminophen and N-acetylcysteine through suppression of the NLRP3 inflammasome pathway in LPS-challenged piglet mononuclear phagocytes.

Published in:

Innate Immunity, 2015, v. 21, n. 6, p. 587, doi. 10.1177/1753425914566205

By:

Yu Liu;
Wenxu Yao;
Jun Xu;
Yinsheng Qiu;
Fangyuan Cao;
Sali Li;
Sheng Yang;
Hailan Yang;
Zhongyuan Wu;
Yongqing Hou

Publication type:

Article

RhoA/ROCK1 regulates Avian Reovirus S1133-induced switch from autophagy to apoptosis.

Published in:

BMC Veterinary Research, 2015, v. 11, n. 1, p. 1, doi. 10.1186/s12917-015-0417-6

By:

Ping-Yuan Lin;
Ching-Dong Chang;
Yo-Chia Chen;
Wen-Ling Shih

Publication type:

Article

A New Concept: Aß1-42 Generates a Hyperfunctional Proteolytic NCX3 Fragment That Delays Caspase-12 Activation and Neuronal Death.

Published in:

Journal of Neuroscience, 2012, v. 32, n. 31, p. 10609, doi. 10.1523/JNEUROSCI.6429-11.2012

By:

Pannaccione, Anna;
Secondo, Agnese;
Molinaro, Pasquale;
D'Avanzo, Carla;
Cantile, Maria;
Esposito, Alba;
Boscia, Francesca;
Scorziello, Antonella;
Sirabella, Rossana;
Di Renzo, Gianfranco;
Annunziato, Lucio

Publication type:

Article

Caspase-mediated Apoptotic Effects of Diol-type Ginseng Sapogenins on Human Hepatoma Cell Lines.

Published in:

Bulletin of the Korean Chemical Society, 2015, v. 36, n. 1, p. 431, doi. 10.1002/bkcs.10074

By:

Cheon, Gab Jin;
Kim, Ki Hyun;
Park, Jun Yeon;
Lee, Dahae;
Hwang, Gwi Seo;
Kang, Ki Sung;
Jang, Hyuk-Jai;
Kwak, Jin Ho;
Choi, Kun Moo;
Kim, Ji Hoon;
Ham, Jungyeob;
Lee, Sanghyun;
Eom, Dae-Woon

Publication type:

Article

A Site‐Specific Photo‐Crosslinking Proteomics Approach Provides Insights into Noncanonical Pyroptotic Caspase‐4 Substrates.

Published in:

Angewandte Chemie, 2025, v. 137, n. 21, p. 1, doi. 10.1002/ange.202501535

By:

Zhou, Yi;
Zhang, Xinyu;
Yin, Hang

Publication type:

Article

Apoptosis-Inducing Factor Is Involved in Gentamicin-Induced Vestibular Hair Cell Death.

Published in:

ORL (0301-1569), 2012, v. 74, n. 1, p. 1, doi. 10.1159/000333251

By:

Zhang, Daogong;
Fan, Zhaomin;
Han, Yuechen;
Bai, Xiaohui;
Liu, Wenwen;
Lu, Sumei;
Wang, Mingming;
Xu, Lei;
Luo, Jianfen;
Li, Jianfeng;
Wang, Haibo

Publication type:

Article

Neurological disease: Inflammasome activation in Alzheimer's disease.

Published in:

Nature Reviews Drug Discovery, 2013, v. 12, n. 2, p. 102, doi. 10.1038/nrd3952

By:

Harrison, Charlotte

Publication type:

Article

Unexplained fever with consumptive syndrome in the elderly: two cases of VEXAS syndrome with inflammasome dysregulation.

Published in:

Clinical & Experimental Immunology, 2024, v. 218, n. 2, p. 213, doi. 10.1093/cei/uxae069

By:

Mendonça, Leonardo Oliveira;
Leal, Vinicius N C;
Roa, Mariela E G V;
Barros, Samar Freschi;
Kalil, Jorge;
Pontillo, Alessandra

Publication type:

Article