Works about CASPASE inhibitors

Results: 235

Multiple Apoptotic Caspase Cascades Are Required in Nonapoptotic Roles for Drosophila Spermatid Individualization.

Published in:

PLoS Biology, 2003, v. 1, n. 12, p. 1, doi. 10.1371/journal.pbio.0020015

By:

Huh, Jun R;
Vernooy, Stephanie Y;
Yu, Hong;
Yan, Nieng;
Shi, Yigong;
Guo, Ming;
Hay, Bruce A

Publication type:

Article

The pan-caspase inhibitor Emricasan ( IDN-6556) decreases liver injury and fibrosis in a murine model of non-alcoholic steatohepatitis.

Published in:

Liver International, 2015, v. 35, n. 3, p. 953, doi. 10.1111/liv.12570

By:

Barreyro, Fernando J.;
Holod, Silvia;
Finocchietto, Paola V.;
Camino, Alejandra M.;
Aquino, Jorge B.;
Avagnina, Alejandra;
Carreras, María C.;
Poderoso, Juan J.;
Gores, Gregory J.

Publication type:

Article

In Silico Evaluation: Bioactive Compounds in Soursop Plant (Annona muricata L.) as Caspase-3 Inhibitor for Prostate Cancer.

Published in:

Pharmacy & Pharmaceutical Sciences Journal / Jurnal Farmasi Dan Ilmu Kefarmasian Indonesia, 2024, v. 11, n. 1, p. 1, doi. 10.20473/jfiki.v11i12024.1-11

By:

Aristokrat, Aria;
Rumawan, Maritsa Widati Aqila;
Hanifa, Zahra Amalia;
Rahmani, Syifa Luthfiyah;
Hanifah;
Parameswari, Natashya;
Pribadi, Alya Puteri Agustina;
Aulifa, Diah Lia

Publication type:

Article

Sophorolipids as anticancer agents: progress and challenges.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02303-x

By:

Singh, Salam Bhopen;
Kuniyal, Kanupriya;
Rawat, Ananya;
Bisht, Ananya;
Shah, Vijendra;
Daverey, Achlesh

Publication type:

Article

Licochalcone A Induces Uterine Leiomyoma Cell Apoptosis via the ROS-Mediated JNK Activation of the GRP78/NRF2 Pathway In Vitro and In Vivo.

Published in:

Antioxidants, 2025, v. 14, n. 2, p. 148, doi. 10.3390/antiox14020148

By:

Chien, Hung-Ju;
Hu, Huang-Ming;
Tsai, Su-Ju;
Lin, Chu-Liang;
Yang, Shun-Fa;
Chen, Ju-Kai;
Liu, Chung-Jung;
Hsieh, Yi-Hsien

Publication type:

Article

Metabolomics Reveals the Efficacy of Caspase Inhibition for Saikosaponin D-Induced Hepatotoxicity.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00732

By:

Zhang, Qian-qian;
Huang, Wan-qiu;
Gao, Yi-qiao;
Han, Zhao-di;
Zhang, Wei;
Zhang, Zun-jian;
Xu, Feng-guo

Publication type:

Article

Immunogenic cell death after combined treatment with radiation and ATR inhibitors is dually regulated by apoptotic caspases.

Published in:

Frontiers in Immunology, 2023, p. 01, doi. 10.3389/fimmu.2023.1138920

By:

Mariampillai, Adrian Eek;
Hauge, Sissel;
Kongsrud, Karoline;
Syljuásen, Randi G.

Publication type:

Article

Identification of hub genes associated with RNAi-induced silencing of XIAP through targeted proteomics approach in MCF7 cells.

Published in:

Cell & Bioscience, 2020, v. 10, n. 1, p. 1, doi. 10.1186/s13578-020-00437-9

By:

Gholizadeh, Mehdi Agha;
Shamsabadi, Fatemeh T.;
Yamchi, Ahad;
Golalipour, Masoud;
Jhingan, Gagan Deep;
Shahbazi, Majid

Publication type:

Article

Programmed cell death during quinoa perisperm development.

Published in:

Journal of Experimental Botany, 2013, v. 64, n. 11, p. 3313

By:

López-Fernández, María Paula;
Maldonado, Sara

Publication type:

Article

Molecular mechanism of CAIF inhibiting myocardial infarction by sponging miR-488 and regulating AVEN expression.

Published in:

Molecular Medicine Reports, 2022, v. 26, n. 2, p. N.PAG, doi. 10.3892/mmr.2022.12786

By:

Li, Xiaoling;
Chen, Runqi;
Wang, Lina;
Lu, Zengxue;
Li, Yangjie;
Tang, Dun

Publication type:

Article

Dracorhodin perchlorate induces apoptosis and G2/M cell cycle arrest in human esophageal squamous cell carcinoma through inhibition of the JAK2/STAT3 and AKT/FOXO3a pathways.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 3, p. 2091, doi. 10.3892/mmr.2019.10474

By:

Lu, Zhengyang;
Lu, Chenyang;
Li, Cheng;
Jiao, Yan;
Li, Yanqing;
Zhang, Guangxin

Publication type:

Article

Effects of Lycium barbarum polysaccharides on the damage to human endometrial stromal cells induced by hydrogen peroxide.

Published in:

Molecular Medicine Reports, 2017, v. 15, n. 2, p. 879, doi. 10.3892/mmr.2016.6080

By:

Tieying Shan;
Tieqiang Shan;
Fengli Liu;
Haiping Zheng;
Guiying Li

Publication type:

Article

Fas expression is downregulated in gastric cancer.

Published in:

Molecular Medicine Reports, 2017, v. 15, n. 2, p. 627, doi. 10.3892/mmr.2016.6037

By:

Xuming Wang;
Zhengqi Fu;
Ying Chen;
Lijiang Liu

Publication type:

Article

Nuclear distribution of eIF3g and its interacting nuclear proteins in breast cancer cells.

Published in:

Molecular Medicine Reports, 2016, v. 13, n. 4, p. 2973, doi. 10.3892/mmr.2016.4935

By:

QIAOLI ZHENG;
HAO LIU;
JINGJIA YE;
HUI ZHANG;
ZHENYU JIA;
JIANG CAO

Publication type:

Article

Epigallocatechin-3-gallate suppresses alveolar epithelial cell apoptosis in seawater aspiration-induced acute lung injury via inhibiting STAT1-caspase-3/p21 associated pathway.

Published in:

Molecular Medicine Reports, 2016, v. 13, n. 1, p. 829, doi. 10.3892/mmr.2015.4617

By:

WEI LIU;
MINGQING DONG;
LIYAN BO;
CONGCONG LI;
QINGQING LIU;
ZHICHAO LI;
FAGUANG JIN

Publication type:

Article

Rocaglamide overcomes tumor necrosis factor-related apoptosis-inducing ligand resistance in hepatocellular carcinoma cells by attenuating the inhibition of caspase-8 through cellular FLICE-like-inhibitory protein downregulation.

Published in:

Molecular Medicine Reports, 2015, v. 11, n. 1, p. 203, doi. 10.3892/mmr.2014.2718

By:

ZHOU LUAN;
YING HE;
FAN HE;
ZHISHUI CHEN

Publication type:

Article

Protective effects of the p38 MAPK inhibitor SB203580 on NMDA-induced injury in primary cerebral cortical neurons.

Published in:

Molecular Medicine Reports, 2014, v. 10, n. 4, p. 1942, doi. 10.3892/mmr.2014.2402

By:

XUE-WEN LIU;
EN-FEI JI;
PENG HE;
RUI-XIAN XING;
BU-XIAN TIAN;
XI-DONG LI

Publication type:

Article

Radioprotective effect of a pan-caspase inhibitor in a novel model of radiation injury to the nucleus of the abducens nerve.

Published in:

Molecular Medicine Reports, 2014, v. 10, n. 3, p. 1433, doi. 10.3892/mmr.2014.2334

By:

JIANGUO LI;
LI LIN;
LIQING DU;
CHANG XU;
YAN WANG;
JIA CAO;
QIN WANG;
FEIYUE FAN;
XIAOPING WANG;
YAFEI WANG;
QIANG LIU

Publication type:

Article

Capsaicin induces apoptosis in MG63 human osteosarcoma cells via the caspase cascade and the antioxidant enzyme system.

Published in:

Molecular Medicine Reports, 2013, v. 8, n. 6, p. 1655, doi. 10.3892/mmr.2013.1737

By:

WON HO CHO;
HYUN JOO LEE;
YOON JI CHOI;
JOO HAN OH;
HAN SOO KIM;
HWAN SEONG CHO

Publication type:

Article

Virus Infection and Death Receptor-Mediated Apoptosis.

Published in:

Viruses (1999-4915), 2017, v. 9, n. 11, p. 316, doi. 10.3390/v9110316

By:

Xingchen Zhou;
Wenbo Jiang;
Zhongshun Liu;
Shuai Liu;
Xiaozhen Liang

Publication type:

Article

Inhibition of autophagy enhances the effects of the AKT inhibitor MK-2206 when combined with paclitaxel and carboplatin in BRAF wild-type melanoma.

Published in:

Pigment Cell & Melanoma Research, 2014, v. 27, n. 3, p. 465, doi. 10.1111/pcmr.12227

By:

Rebecca, Vito W.;
Massaro, Renato R.;
Fedorenko, Inna V.;
Sondak, Vernon K.;
Anderson, Alexander R. A.;
Kim, Eunjung;
Amaravadi, Ravi K.;
Maria ‐ Engler, Silvya S.;
Messina, Jane L.;
Gibney, Geoffrey T.;
Kudchadkar, Ragini R.;
Smalley, Keiran S. M.

Publication type:

Article

The Effects of Aging on Apoptosis Following Myocardial Infarction.

Published in:

Cardiovascular Therapeutics, 2013, v. 31, n. 6, p. e102, doi. 10.1111/1755-5922.12043

By:

Boyle, Andrew J.;
Hwang, Joy;
Ye, Jianqin;
Shih, Henry;
Jun, Kristine;
Zhang, Yan;
Fang, Qizhi;
Sievers, Richard;
Yeghiazarians, Yerem;
Lee, Randall J.

Publication type:

Article

Apoptotic Vascular Smooth Muscle Cell Depletion via BCL2 Family of Proteins in Human Ascending Aortic Aneurysm and Dissection.

Published in:

Cardiovascular Therapeutics, 2012, v. 30, n. 6, p. 308, doi. 10.1111/1755-5922.12007

By:

Durdu, Serkan;
Deniz, Gunseli C.;
Balci, Deniz;
Zaim, Cagin;
Dogan, Arin;
Can, Alp;
Akcali, Kamil C.;
Akar, Ahmet Ruchan

Publication type:

Article

Inflammasomes as contributors to periodontal disease.

Published in:

2020

By:

Marchesan, Julie T.

Publication type:

journal article

Caspase-1 Inhibition Attenuates Hyperoxia-induced Lung and Brain Injury in Neonatal Mice.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2019, v. 61, n. 3, p. 341, doi. 10.1165/rcmb.2018-0192OC

By:

Dapaah-Siakwan, Fredrick;
Zambrano, Ronald;
Shihua Luo;
Duncan, Matthew R.;
Kerr, Nadine;
Donda, Keyur;
de Rivero Vaccari, Juan Pablo;
Keane, Robert W.;
Dietrich, W. Dalton;
Benny, Merline;
Young, Karen;
Shu Wu

Publication type:

Article

Induction of apoptosis and hypoxic stress in malignant melanoma cells via graphene-mediated far-infrared radiation.

Published in:

BMC Cancer, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12885-025-14031-0

By:

Zhao, Wumei;
Chen, Ziwen;
Fu, Wenxing;
Ye, Chenyan;
Fu, Haijing;
Xu, Tianyi;
Wu, Binghui;
Chen, Lina;
Shan, Shi-Jun

Publication type:

Article

Dimethyl tyrosine conjugated peptide prevents oxidative damage and death of triticale and wheat microspores.

Published in:

Plant Cell, Tissue & Organ Culture, 2015, v. 122, n. 1, p. 227, doi. 10.1007/s11240-015-0763-x

By:

Sinha, Rakesh;
Eudes, François

Publication type:

Article

Survival of auditory hair cells.

Published in:

Cell & Tissue Research, 2015, v. 361, n. 1, p. 59, doi. 10.1007/s00441-015-2152-5

By:

Seymour, Michelle;
Pereira, Fred

Publication type:

Article

Antiproliferative in vitro effects of BI 2536-mediated PLK1 inhibition on cervical adenocarcinoma cells.

Published in:

Clinical & Experimental Medicine, 2013, v. 13, n. 1, p. 75, doi. 10.1007/s10238-011-0166-1

By:

Pezuk, Julia;
Brassesco, María;
Oliveira, Jaqueline;
Morales, Andressa;
Montaldi, Ana;
Sakamoto-Hojo, Elza;
Scrideli, Carlos;
Tone, Luiz

Publication type:

Article

Identification of a specific inhibitor of nOGA - a caspase-3 cleaved O-GlcNAcase variant during apoptosis.

Published in:

Biochemistry (00062979), 2012, v. 77, n. 2, p. 194, doi. 10.1134/S0006297912020113

By:

Li, Jing;
Li, Zhonghua;
Li, Tiehai;
Lin, Lin;
Zhang, Yan;
Guo, Lina;
Xu, Yan;
Zhao, Wei;
Wang, Peng

Publication type:

Article

A novel small molecule, Rosline, inhibits growth and induces caspase-dependent apoptosis in human lung cancer cells A549 through a reactive oxygen species-dependent mechanism.

Published in:

Cell Biology International, 2016, v. 40, n. 6, p. 686, doi. 10.1002/cbin.10606

By:

Zhao, Ting;
Feng, Yang;
Jin, Wenling;
Pan, Hui;
Li, Haizhou;
Zhao, Yang

Publication type:

Article

An inhibitory role for caspase-3 at the late stage of RANKL-induced osteoclast differentiation in RAW264 cells and mouse bone marrow macrophages.

Published in:

Cell Biology International, 2014, v. 38, n. 6, p. 723, doi. 10.1002/cbin.10263

By:

Katao, Yuko;
Shishido, Mika;
Inami, Kaoru;
Matsumoto, Naoyuki;
Sawai, Hirofumi

Publication type:

Article

Genistein induces apoptotic cell death associated with inhibition of the NF-κB pathway in adult T-cell leukemia cells.

Published in:

Cell Biology International, 2013, v. 37, n. 7, p. 742, doi. 10.1002/cbin.10101

By:

Yamasaki, Masao;
Mine, Yoshihiro;
Nishimura, Misato;
Fujita, Satoshi;
Sakakibara, Yoichi;
Suiko, Masahito;
Morishita, Kazuhiro;
Nishiyama, Kazuo

Publication type:

Article

Pharmacological doses of melatonin induce alterations in mitochondrial mass and potential, bcl-2 levels and K<sup>+</sup> currents in UVB-exposed U937 cells.

Published in:

Cell Biology International, 2013, v. 37, n. 3, p. 213, doi. 10.1002/cbin.10030

By:

Canonico, Barbara;
Luchetti, Francesca;
Ambrogini, Patrizia;
Arcangeletti, Marcella;
Betti, Michele;
Cesarini, Erica;
Lattanzi, Davide;
Ciuffoli, Stefano;
Palma, Fulvio;
Cuppini, Riccardo;
Papa, Stefano

Publication type:

Article

Lidocaine-induced apoptosis of gingival fibroblasts: participation of cAMP and PKC activity.

Published in:

Cell Biology International, 2011, v. 35, n. 8, p. 783, doi. 10.1042/CBI20100200

By:

Villarruel, Emmanuel Quinteros;
Borda, Enri;
Sterin-Borda, Leonor;
Orman, Betina

Publication type:

Article

Naringin ameliorates sodium arsenite-induced renal and hepatic toxicity in rats: decisive role of KIM-1, Caspase-3, TGF- β , and TNF- α.

Published in:

Renal Failure, 2015, v. 37, n. 8, p. 1396, doi. 10.3109/0886022X.2015.1074462

By:

Adil, Mohammad;
Kandhare, Amit D.;
Visnagri, Asjad;
Bodhankar, Subhash L.

Publication type:

Article

A pan caspase inhibitor decreases caspase-1, IL-1 α and IL-1 β, and protects against necrosis of cisplatin-treated freshly isolated proximal tubules.

Published in:

Renal Failure, 2015, v. 37, n. 1, p. 144, doi. 10.3109/0886022X.2014.970194

By:

Lee, Dong Won;
Faubel, Sarah;
Edelstein, Charles L.

Publication type:

Article

Activation of Caspase-8 and Caspase-9 are Required for PC12 Cells Differentiation.

Published in:

Journal of Immunoassay & Immunochemistry, 2015, v. 36, n. 5, p. 547, doi. 10.1080/15321819.2015.1017106

By:

Mogi, Makio;
Kondo, Ayami

Publication type:

Article

Using a Natural Triterpenoid to Unlock the Antitumor Effects of Autophagy in B-Cell Lymphoma.

Published in:

Biomedicines, 2025, v. 13, n. 2, p. 445, doi. 10.3390/biomedicines13020445

By:

Doonan, Bently P.;
Radwan, Faisal F. Y.;
Banik, Naren L.;
Haque, Azizul

Publication type:

Article

TGF-β/Smad3 pathway enhances the cardio-protection of S1R/SIPR1 in in vitro ischemia-reperfusion myocardial cell model.

Published in:

Experimental & Therapeutic Medicine, 2018, v. 16, n. 1, p. 178, doi. 10.3892/etm.2018.6192

By:

Yang, Tingfang;
Zhang, Xianfeng;
Ma, Cuimei;
Chen, Yan

Publication type:

Article

Inhibition of periderm removal in all-trans retinoic acid-induced cleft palate in mice.

Published in:

Experimental & Therapeutic Medicine, 2017, v. 14, n. 4, p. 3393, doi. 10.3892/etm.2017.4938

By:

YA-DONG ZHANG;
SHI-YI DONG;
HONG-ZHANG HUANG

Publication type:

Article

Microcystin-LR induces mitochondria-mediated apoptosis in human bronchial epithelial cells.

Published in:

Experimental & Therapeutic Medicine, 2016, v. 12, n. 2, p. 633, doi. 10.3892/etm.2016.3423

By:

YANG LI;
JINHUI LI;
HUI HUANG;
MINGFENG YANG;
DONGGANG ZHUANG;
XUEMIN CHENG;
HUIZHEN ZHANG;
XIAOLI FU

Publication type:

Article

Caspase-3 inhibitor prevents the apoptosis of brain tissue in rats with acute cerebral infarction.

Published in:

Experimental & Therapeutic Medicine, 2015, v. 10, n. 1, p. 133, doi. 10.3892/etm.2015.2462

By:

YUHUA SUN;
YUMING XU;
LIJIAO GENG

Publication type:

Article

Radiation-induced cytochrome c release and the neuroprotective effects of the pan-caspase inhibitor z-VAD-fmk in the hypoglossal nucleus.

Published in:

Experimental & Therapeutic Medicine, 2014, v. 7, n. 2, p. 383, doi. 10.3892/etm.2013.1419

By:

JIANGUO LI;
YAN WANG;
LIQING DU;
CHANG XU;
JIA CAO;
QIN WANG;
QIANG LIU;
FEIYUE FAN

Publication type:

Article

Ibuprofen‑derived nitric oxide donors with a high affinity to human serum albumin induce cell death in pancreatic cancer cells through a non‑caspase 3/7‑mediated pathway.

Published in:

Biomedical Reports, 2024, v. 21, n. 5, p. N.PAG, doi. 10.3892/br.2024.1847

By:

Nishi, Koji;
Arimura, Yoshifumi;
Suetsugi, Naho;
Beppu, Takuro;
Takasaki, Kaho;
Tamori, Ayano;
Kanda, Ryo;
Imoto, Shuhei;
Murase, Hirotaka;
Tsukigawa, Kenji;
Otagiri, Masaki;
Yamasaki, Keishi

Publication type:

Article

The immobilization of human spermatozoa by STAT3 inhibitory compound V results from an excessive intracellular amount of reactive oxygen species.

Published in:

Andrology, 2016, v. 4, n. 1, p. 133, doi. 10.1111/andr.12123

By:

Lachance, C.;
Goupil, S.;
Tremblay, R. R.;
Leclerc, P.

Publication type:

Article

The MEK-ERK-MST1 Axis Potentiates the Activation of the Extrinsic Apoptotic Pathway during GDC-0941 Treatment in Jurkat T Cells.

Published in:

Cells (2073-4409), 2019, v. 8, n. 2, p. 191, doi. 10.3390/cells8020191

By:

Nováková, Jana;
Talacko, Pavel;
Novák, Petr;
Vališ, Karel

Publication type:

Article

Tubeimoside-2 Triggers Methuosis in Hepatocarcinoma Cells through the MKK4–p38α Axis.

Published in:

Pharmaceutics, 2023, v. 15, n. 4, p. 1093, doi. 10.3390/pharmaceutics15041093

By:

Gan, Yichao;
Wang, Chen;
Chen, Yunyun;
Hua, Linxin;
Fang, Hui;
Li, Shu;
Chai, Shoujie;
Xu, Yang;
Zhang, Jiawei;
Gu, Ying

Publication type:

Article

Caspase-1 inhibition attenuates activation of BV2 microglia induced by LPS-treated RAW264.7 macrophages.

Published in:

Journal of Biomedical Research, 2016, v. 30, n. 3, p. 225, doi. 10.7555/JBR.30.20150141

By:

Yang Pan;
Bo Shen;
Qin Gao;
Jun Zhu;
Jingde Dong;
Li Zhang;
Yingdong Zhang

Publication type:

Article

Potency of mycotoxin binders on MDA level, expressions of caspase 9 and caspase 3 in the uterus of mice exposed to zearalenone.

Published in:

Iraqi Journal of Veterinary Sciences, 2017, v. 31, n. 1, p. 29, doi. 10.33899/ijvs.2017.126707

By:

Samik, A.;
Safitri, E.

Publication type:

Article