Works matching DE "CARBONYL reductase"

Results: 172

Modification of carbonyl reductase based on substrate pocket loop regions alteration: an application for synthesis of duloxetine chiral intermediate in high efficiency.

Published in:

Bioprocess & Biosystems Engineering, 2025, v. 48, n. 6, p. 927, doi. 10.1007/s00449-025-03152-2

By:

Zhang, Xiao-Jian;
Chen, Kai-Li;
Li, Xiang-Yang;
Yuan, Qi-Qi;
Lin, Chao-Ping;
Liu, Zhi-Qiang;
Zheng, Yu-Guo

Publication type:

Article

Human skeletal muscle possesses both reversible proteomic signatures and a retained proteomic memory after repeated resistance training.

Published in:

Journal of Physiology, 2025, v. 603, n. 9, p. 2655, doi. 10.1113/JP288104

By:

Hulmi, Juha J.;
Halonen, Eeli J.;
Sharples, Adam P.;
O'Connell, Thomas M.;
Kuikka, Lauri;
Lappi, Veli‐Matti;
Salokas, Kari;
Keskitalo, Salla;
Varjosalo, Markku;
Ahtiainen, Juha P.

Publication type:

Article

One pot simultaneous preparation of both enantiomer of β-amino alcohol and vicinal diol via cascade biocatalysis.

Published in:

Biotechnology Letters, 2018, v. 40, n. 2, p. 349, doi. 10.1007/s10529-017-2471-6

By:

Zhao, Jian-Wei;
Wu, Hua-Lei;
Zhang, Jian-Dong;
Gao, Wen-Chao;
Fan, Xiao-Jun;
Chang, Hong-Hong;
Wei, Wen-Long;
Xu, Jian-He

Publication type:

Article

A novel carbonyl reductase with anti-Prelog stereospecificity for the production of t-butyl 6-cyano-(3R, 5R)-dihydroxyhexanoate.

Published in:

3 Biotech, 2019, v. 9, n. 5, p. N.PAG, doi. 10.1007/s13205-019-1722-8

By:

Jin, Qingchao;
Wu, Zhige;
Dou, Yanping;
Yang, Yu;
Xia, Jingjing;
Jin, Zhihua

Publication type:

Article

Promotion of the Asymmetric Reduction of Prochiral Ketone with Recombinant E. coli Through Strengthening Intracellular NADPH Supply by Modifying EMP and Introducing NAD Kinase.

Published in:

Catalysis Letters, 2021, v. 151, n. 9, p. 2527, doi. 10.1007/s10562-020-03490-8

By:

Du, Hui-Jun;
Luo, Wei;
Appiah, Bright;
Zou, Zhi-Cheng;
Yang, Zhong-Hua;
Zeng, Rong;
Luo, Li

Publication type:

Article

An Alkali-tolerant Carbonyl Reductase from Bacillus subtilis by Gene Mining: Identification and Application.

Published in:

Catalysis Letters, 2019, v. 149, n. 11, p. 2973, doi. 10.1007/s10562-019-02873-w

By:

Luo, Wei;
Du, Hui-Jun;
Bonku, Emmanuel Mintah;
Hou, Ya-Li;
Li, Ling-Ling;
Wang, Xiao-Qiang;
Yang, Zhong-Hua

Publication type:

Article

Human aldo-keto reductases: structure, substrate specificity and roles in tumorigenesis.

Published in:

Biomolecular Concepts, 2011, v. 2, n. 1/2, p. 115, doi. 10.1515/BMC.2011.010

By:

Jun Ma;
Deliang Cao

Publication type:

Article

Preparation, Properties and Crystal Structure of syn-Isomer of 2,6-Dichlorophenyl-cyanoxime, H(2,6-diCl-PhCO): Potent Carbonyl Reductase Inhibitor.

Published in:

Journal of Chemical Crystallography, 2022, v. 52, n. 2, p. 194, doi. 10.1007/s10870-021-00905-1

By:

Amankrah, Seth Adu;
Hietsoi, Oleksandr;
Tyukhtenko, Sergiy;
Gerasimchuk, Nikolay;
Charlier, Henry

Publication type:

Article

Reengineered carbonyl reductase for reducing methyl-substituted cyclohexanones.

Published in:

PEDS: Protein Engineering, Design & Selection, 2013, v. 26, n. 4, p. 291, doi. 10.1093/protein/gzt001

By:

Jakoblinnert, Andre;
Wachtmeister, Jochen;
Schukur, Lina;
Shivange, Amol V.;
Bocola, Marco;
Ansorge-Schumacher, Marion B.;
Schwaneberg, Ulrich

Publication type:

Article

Human DCXR - another 'moonlighting protein' involved in sugar metabolism, carbonyl detoxification, cell adhesion and male fertility?

Published in:

Biological Reviews, 2015, v. 90, n. 1, p. 254, doi. 10.1111/brv.12108

By:

Ebert, Bettina;
Kisiela, Michael;
Maser, Edmund

Publication type:

Article

A genomic search approach to identify carbonyl reductases in Gluconobacter oxydans for enantioselective reduction of ketones.

Published in:

Bioscience, Biotechnology & Biochemistry, 2014, v. 78, n. 8, p. 1350, doi. 10.1080/09168451.2014.925775

By:

Rong Chen;
Xu Liu;
Jinping Lin;
Dongzhi Wei

Publication type:

Article

Flufenamic acid alleviates sepsis‐induced lung injury by up‐regulating CBR1.

Published in:

Drug Development Research, 2020, v. 81, n. 7, p. 885, doi. 10.1002/ddr.21706

By:

Jiang, Qiannan;
Chen, Zhenzhen;
Jiang, Hong

Publication type:

Article

Risk factors for anthracycline-associated cardiotoxicity.

Published in:

2016

By:

Reinbolt, Raquel;
Patel, Roshan;
Pan, Xueliang;
Timmers, Cynthia;
Pilarski, Robert;
Shapiro, Charles;
Lustberg, Maryam;
Reinbolt, Raquel E;
Timmers, Cynthia Dawn;
Shapiro, Charles L;
Lustberg, Maryam B

Publication type:

journal article

In Silico and In Vitro Assessment of Carbonyl Reductase 1 Inhibition Using ASP9521—A Potent Aldo-Keto Reductase 1C3 Inhibitor with the Potential to Support Anticancer Therapy Using Anthracycline Antibiotics.

Published in:

Molecules, 2023, v. 28, n. 9, p. 3767, doi. 10.3390/molecules28093767

By:

Jamrozik, Marek;
Piska, Kamil;
Bucki, Adam;
Koczurkiewicz-Adamczyk, Paulina;
Sapa, Michał;
Władyka, Benedykt;
Pękala, Elżbieta;
Kołaczkowski, Marcin

Publication type:

Article

Enzymes, Biocatalysis and Chemical Biology.

Published in:

2020

By:

Serra, Stefano

Publication type:

Editorial

Tris(pentafluorophenyl)borane-Catalyzed Reactions Using Silanes.

Published in:

Molecules, 2019, v. 24, n. 3, p. 432, doi. 10.3390/molecules24030432

By:

Hackel, Taylor;
McGrath, Nicholas A.;
He, Huixin;
Ma, Ning

Publication type:

Article

Characterization of a Carbonyl Reductase from Rhodococcus erythropolis WZ010 and Its Variant Y54F for Asymmetric Synthesis of (S)-N-Boc-3-Hydroxypiperidine.

Published in:

Molecules, 2018, v. 23, n. 12, p. 3117, doi. 10.3390/molecules23123117

By:

Ying, Xiangxian;
Zhang, Jie;
Wang, Can;
Huang, Meijuan;
Ji, Yuting;
Cheng, Feng;
Yu, Meilan;
Wang, Zhao;
Ying, Meirong;
Serra, Stefano

Publication type:

Article

Production of Flavours and Fragrances via Bioreduction of (4R)-(-)-Carvone and (1R)-(-)-Myrtenal by Non-Conventional Yeast Whole-Cells.

Published in:

Molecules, 2013, v. 18, n. 5, p. 5736, doi. 10.3390/molecules18055736

By:

Goretti, Marta;
Turchetti, Benedetta;
Cramarossa, Maria Rita;
Forti, Luca;
Buzzini, Pietro

Publication type:

Article

Phosphotungstic Acid: An Efficient, Cost-effective and Recyclable Catalyst for the Synthesis of Polysubstituted Quinolines.

Published in:

Molecules, 2009, v. 14, n. 3, p. 1126, doi. 10.3390/molecules14031126

By:

Dabiri, Minoo;
Bashiribod, Sahareh

Publication type:

Article

Bioreduction of N-(3-oxobutyl)heterocycles with flexible ring by yeast whole-cell biocatalysts.

Published in:

Applied Microbiology & Biotechnology, 2025, v. 109, n. 1, p. 1, doi. 10.1007/s00253-025-13486-2

By:

Honvári, Máté Gergő;
Kucsinka, Bence Attila;
Mócza, Levente András;
Csuka, Pál;
Bódai, Viktória;
Poppe, László;
Hornyánszky, Gábor

Publication type:

Article

Principal Component Analysis Reveals Age-Related and Muscle-Type-Related Differences in Protein Carbonyl Profiles of Muscle Mitochondria.

Published in:

Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2008, v. 63, n. 12, p. 1277, doi. 10.1093/gerona/63.12.1277

By:

Feng, Juan;
Navratil, Marian;
Thompson, LaDora V.;
Arriaga, Edgar A.

Publication type:

Article

Characterization of human CRB gene product by the use of bioinformatic tools.

Published in:

Albanian Journal of Agricultural Sciences, 2017, p. 347

By:

BOZGO, VILSON;
HYSI, LORENA;
HODA, ANILA

Publication type:

Article

Characterization of the enzymes involved in the in vitro metabolism of amrubicin hydrochloride.

Published in:

Xenobiotica, 2005, v. 35, n. 12, p. 1121, doi. 10.1080/00498250500342746

By:

Tani, N.;
Yabuki, M.;
Komuro, S.;
Kanamaru, H.

Publication type:

Article

Differential hormonal regulation of carbonyl reductase activities in liver and kidney microsomes of rat.

Published in:

Xenobiotica, 2002, v. 32, n. 9, p. 729, doi. 10.1080/00498250210144848

By:

Imamura, Y.;
Takada, H.;
Kamizono, R.;
Otagiri, M.

Publication type:

Article

Ontogenic pattern of carbonyl reductase activity of 11{beta}-hydroxysteroid dehydrogenase in mouse liver and kidney

Published in:

Xenobiotica, 1994, v. 24, n. 2, p. 109

By:

Freibertshauser, J.;
Maser, E.;
Mangoura, S. A.

Publication type:

Article

Integrating plasma proteomes with genome-wide association data for causal protein identification in multiple myeloma.

Published in:

BMC Medicine, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12916-023-03086-0

By:

Wang, Qiangsheng;
Shi, Qiqin;
Wang, Zhenqian;
Lu, Jiawen;
Hou, Jian

Publication type:

Article

Activity prediction of substrates in NADH-dependent carbonyl reductase by docking requires catalytic constraints and charge parameterization of catalytic zinc environment.

Published in:

Journal of Computer-Aided Molecular Design, 2015, v. 29, n. 11, p. 1057, doi. 10.1007/s10822-015-9878-8

By:

Dhoke, Gaurao;
Loderer, Christoph;
Davari, Mehdi;
Ansorge-Schumacher, Marion;
Schwaneberg, Ulrich;
Bocola, Marco

Publication type:

Article

Asymmetric synthesis of tert-butyl (3R,5S)-6-chloro-3,5-dihydroxyhexanoate using a self-sufficient biocatalyst based on carbonyl reductase and cofactor co-immobilization.

Published in:

Bioprocess & Biosystems Engineering, 2020, v. 43, n. 1, p. 21, doi. 10.1007/s00449-019-02201-x

By:

Zhang, Xiao-Jian;
Wang, Wen-Zhong;
Zhou, Rong;
Liu, Zhi-Qiang;
Zheng, Yu-Guo

Publication type:

Article

Rational design of the carbonyl reductase EbSDR8 for efficient biosynthesis of enantiopure (R)-3-chloro-1-phenyl-1-propanol.

Published in:

Applied Microbiology & Biotechnology, 2020, v. 104, n. 21, p. 9219, doi. 10.1007/s00253-020-10904-5

By:

Shao, Ze-Hui;
Su, Bing-Mei;
Yang, Sheng-Li;
Ye, Li-Dan;
Yu, Hong-Wei

Publication type:

Article

Characterization of two carbonyl reductases from Ogataea polymorpha NBRC 0799.

Published in:

Applied Microbiology & Biotechnology, 2018, v. 102, n. 3, p. 1307, doi. 10.1007/s00253-017-8668-8

By:

Isobe, Kimiyasu;
Miki, Shinsuke;
Ueda, Ryoko;
Shichida, Sayaka;
Matsui, Daisuke;
Oku, Yuko;
Asano, Yasuhisa

Publication type:

Article

Crystal structure and iterative saturation mutagenesis of ChKRED20 for expanded catalytic scope.

Published in:

Applied Microbiology & Biotechnology, 2017, v. 101, n. 23/24, p. 8395, doi. 10.1007/s00253-017-8556-2

By:

Zhao, Feng-Jiao;
Jin, Yun;
Liu, Zhongchuan;
Guo, Chao;
Li, Tong-Biao;
Li, Zi-Yi;
Wang, Ganggang;
Wu, Zhong-Liu

Publication type:

Article

Upscale production of ethyl ( S)-4-chloro-3-hydroxybutanoate by using carbonyl reductase coupled with glucose dehydrogenase in aqueous-organic solvent system.

Published in:

Applied Microbiology & Biotechnology, 2015, v. 99, n. 5, p. 2119, doi. 10.1007/s00253-014-6245-y

By:

Liu, Zhi-Qiang;
Ye, Jing-Jing;
Shen, Zhen-Yang;
Hong, Hua-Bin;
Yan, Jian-Bo;
Lin, Yi;
Chen, Zheng-Xu;
Zheng, Yu-Guo;
Shen, Yin-Chu

Publication type:

Article

Cloning, expression, and directed evolution of carbonyl reductase from Leifsonia xyli HS0904 with enhanced catalytic efficiency.

Published in:

Applied Microbiology & Biotechnology, 2014, v. 98, n. 20, p. 8591, doi. 10.1007/s00253-014-5770-z

By:

Wang, Neng-Qiang;
Sun, Jing;
Huang, Jin;
Wang, Pu

Publication type:

Article

Characterization of a newly synthesized carbonyl reductase and construction of a biocatalytic process for the synthesis of ethyl ( S)-4-chloro-3-hydroxybutanoate with high space-time yield.

Published in:

Applied Microbiology & Biotechnology, 2014, v. 98, n. 4, p. 1671, doi. 10.1007/s00253-013-5042-3

By:

You, Zhong-Yu;
Liu, Zhi-Qiang;
Zheng, Yu-Guo

Publication type:

Article

Chemical and enzymatic approaches to the synthesis of optically pure ethyl ( R)-4-cyano-3-hydroxybutanoate.

Published in:

Applied Microbiology & Biotechnology, 2014, v. 98, n. 1, p. 11, doi. 10.1007/s00253-013-5357-0

By:

You, Zhong-Yu;
Liu, Zhi-Qiang;
Zheng, Yu-Guo

Publication type:

Article

In vitro antiproliferative and cytotoxic activities of novel kojic acid derivatives: 5-benzyloxy-2-selenocyanatomethyl- and 5-methoxy-2-selenocyanatomethyl-4-pyranone.

Published in:

Journal of Applied Toxicology, 2008, v. 28, n. 4, p. 554, doi. 10.1002/jat.1300

By:

Fickova, Maria;
Pravdova, Eliska;
Rondhal, Lars;
Uher, Michal;
Brtko, Julius

Publication type:

Article

Synthesis and uranyl ion adsorption study of cross-linked allyl propionate-maleic anhydride-styrene terpolymer.

Published in:

Turkish Journal of Chemistry, 2010, v. 34, n. 1, p. 99

By:

Akperov, Elchin;
Maharramov, Abel;
Akperov, Oktay

Publication type:

Article

Systematic evaluation of the dihydrogen-oxidising and NAD<sup>++</sup>-reducing soluble [NiFe]-hydrogenase from Ralstonia eutropha H16 as a cofactor regeneration catalyst.

Published in:

Biocatalysis & Biotransformation, 2011, v. 29, n. 6, p. 246, doi. 10.3109/10242422.2011.615393

By:

Ratzka, Juliane;
Lauterbach, Lars;
Lenz, Oliver;
Ansorge-Schumacher, Marion B.

Publication type:

Article

Coexpression of a carbonyl reductase and glucose 6-phosphate dehydrogenase in Pichia pastoris improves the production of (S)-1-phenyl-1,2-ethanediol.

Published in:

Biocatalysis & Biotransformation, 2011, v. 29, n. 5, p. 172, doi. 10.3109/10242422.2011.594881

By:

Geng, Yawei;
Zhang, Rongzhen;
Xu, Yan;
Wang, Shanshan;
Sha, Chong;
Xiao, Rong

Publication type:

Article

Complementary selectivity to (S)-1-phenyl-1,2-ethanediol-forming Candida parapsilosis by expressing its carbonyl reductase in Escherichia coli for (R)-specific reduction of 2-hydroxyacetophenone.

Published in:

Biocatalysis & Biotransformation, 2008, v. 26, n. 3, p. 210, doi. 10.1080/10242420701661537

By:

Nie, Yao;
Xu, Yan;
Yan wang, Hai;
Xu, Na;
Xiao, Rong;
Hao sun, Zhi

Publication type:

Article

Carbonyl Reduction of Flubendazole in the Human Liver: Strict Stereospecificity, Sex Difference, Low Risk of Drug Interactions.

Published in:

Frontiers in Pharmacology, 2019, p. N.PAG, doi. 10.3389/fphar.2019.00600

By:

Kubíček, Vladimír;
Skálová, Lenka;
Skarka, Adam;
Králová, Věra;
Holubová, Jana;
Štěpánková, Jana;
Šubrt, Zdeněk;
Szotáková, Barbora

Publication type:

Article

Effective asymmetric preparation of (R)-1-[3-(trifluoromethyl)phenyl]ethanol with recombinant E. coli whole cells in an aqueous Tween-20/natural deep eutectic solvent solution.

Published in:

AMB Express, 2021, v. 11, n. 1, p. 1, doi. 10.1186/s13568-021-01278-6

By:

Zhuang, Wenjin;
Liu, Hanyu;
Zhang, Ying;
He, Junyao;
Wang, Pu

Publication type:

Article

Highly efficient synthesis of rosuvastatin intermediate using a carbonyl reductase–cofactor co‐immobilized biocatalyst in the non‐aqueous biosystem.

Published in:

Journal of Chemical Technology & Biotechnology, 2021, v. 96, n. 11, p. 3094, doi. 10.1002/jctb.6861

By:

Zhang, Xiao‐Jian;
Wu, Di;
Wang, Wen‐Zhong;
Cao, Min;
Liu, Qian;
Liu, Zhi‐Qiang;
Zheng, Yu‐Guo

Publication type:

Article

Efficient Stereoselective Synthesis of Structurally Diverse γ‐ and δ‐Lactones Using an Engineered Carbonyl Reductase.

Published in:

ChemCatChem, 2019, v. 11, n. 11, p. 2600, doi. 10.1002/cctc.201900382

By:

Chen, Meng;
Zhang, Xiao‐Yan;
Zhang, Chao;
Zheng, Yu‐Cong;
Pan, Jiang;
Xu, Jian‐He;
Bai, Yun‐Peng;
Xing, Chen‐Guang

Publication type:

Article

Structure of NADH-Dependent Carbonyl Reductase (CPCR2) from Candida parapsilosis Provides Insight into Mutations that Improve Catalytic Properties.

Published in:

ChemCatChem, 2014, v. 6, n. 4, p. 1103, doi. 10.1002/cctc.201300788

By:

Man, Henry;
Loderer, Christoph;
Ansorge‐Schumacher, Marion B.;
Grogan, Gideon

Publication type:

Article

A short‐chain carbonyl reductase mutant is an efficient catalyst in the production of (R)‐1,3‐butanediol.

Published in:

Microbial Biotechnology, 2023, v. 16, n. 6, p. 1333, doi. 10.1111/1751-7915.14249

By:

Guo, Xiaoyan;
Gao, Yunfang;
Liu, Fangzheng;
Tao, Yong;
Jin, Haibo;
Wang, Jianjun;
Wu, Sheng

Publication type:

Article

Synthesis, Properties and Crystal Structure of the 2,4-Dichlorophenyl-cyanoxime: A Powerful Carbonyl Reductase Inhibitor.

Published in:

Journal of Chemical Crystallography, 2013, v. 43, n. 3, p. 157, doi. 10.1007/s10870-013-0401-6

By:

Hilton, Michael;
Gerasimchuk, Nikolay;
Silchenko, Svitlana;
Charlier, Henry

Publication type:

Article

Efficient chiral synthesis by Saccharomyces cerevisiae spore encapsulation of Candida parapsilosis Glu228Ser/(S)-carbonyl reductase II and Bacillus sp. YX-1 glucose dehydrogenase in organic solvents.

Published in:

Microbial Cell Factories, 2019, v. 18, n. 1, p. N.PAG, doi. 10.1186/s12934-019-1137-6

By:

Rao, Jingxin;
Zhang, Rongzhen;
Liang, Hongbo;
Gao, Xiao-Dong;
Nakanishi, Hideki;
Xu, Yan

Publication type:

Article

Development of transgenic mice overexpressing mouse carbonyl reductase 1.

Published in:

Molecular Biology Reports, 2023, v. 50, n. 1, p. 531, doi. 10.1007/s11033-022-07994-x

By:

Yokoyama, Minako;
Fujita, Toshitsugu;
Kadonosawa, Yuka;
Tatara, Yota;
Motooka, Daisuke;
Ikawa, Masahito;
Fujii, Hodaka;
Yokoayama, Yoshihito

Publication type:

Article

Inhibitory effect of carbonyl reductase 1 against peritoneal progression of ovarian cancer: evaluation by ex vivo 3D-human peritoneal model.

Published in:

Molecular Biology Reports, 2019, v. 46, n. 5, p. 4685, doi. 10.1007/s11033-019-04788-6

By:

Oikiri, Hiroe;
Asano, Yoshiya;
Matsusaki, Michiya;
Akashi, Mitsuru;
Shimoda, Hiroshi;
Yokoyama, Yoshihito

Publication type:

Article