Works about CAMPTOTHECIN

Results: 1177

Comparative studies on the camptothecin content from Nothapodytes foetida and Ophiorrhiza species.

Published in:

Natural Product Research, 2006, v. 20, n. 1, p. 85, doi. 10.1080/15216540500092898

By:

Roja, G.

Publication type:

Article

Camptothecin and its analogues: a review on their chemotherapeutic potential.

Published in:

Natural Product Research, 2005, v. 19, n. 4, p. 393, doi. 10.1080/14786410412331299005

By:

Sriram, Dharmarajan;
Yogeeswari, Perumal;
Thirumurugan, Rathinasabapathy;
Ratan Bal, Tanushree

Publication type:

Article

Self‐Assembly of Antisense DNA‐Camptothecin Amphiphile into Glutathione‐Responsive Nanoparticles for Combination Cancer Therapy.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 13, p. 1, doi. 10.1002/chem.202404068

By:

Krishna, Anusree;
Babulal, Anupama;
Sajeev, Mareena;
Ravi, Nidhin;
Raj, Gowtham;
Antony, Anitta;
Dev Narendradev, Nikhil;
Murty Srinivasula, Srinivasa;
Varghese, Reji

Publication type:

Article

Photo‐Triggered ROS‐Responsive Supramolecular Nanoprodrugs for Targeted and Synergistic Chemo/Photodynamic/Gas Therapy.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 1, p. 1, doi. 10.1002/chem.202403514

By:

Shi, Jingtao;
Ma, Ke;
Yang, Yibo;
Pei, Yuxin;
Pei, Zhichao

Publication type:

Article

Dual Acid-Responsive Micelle-Forming Anticancer Polymers as New Anticancer Therapeutics.

Published in:

Advanced Functional Materials, 2014, v. 23, n. 40, p. 5091, doi. 10.1002/adfm201300871

By:

Kim, Byungkuk;
Lee, Eunsun;
Kim, Yerang;
Park, Sanga;
Khang, Gilson;
Lee, Dongwon

Publication type:

Article

Comparison of seven colchicine-induced tetraploid clones with their original diploid clones in purple coneflower ( Echinacea purpurea L.).

Published in:

Euphytica, 2016, v. 207, n. 2, p. 387, doi. 10.1007/s10681-015-1556-3

By:

Chen, Rong;
Jiang, Wei-zhen;
Li, Qing-ling;
Li, Xin-lian;
Chen, Xiao-lu;
Yang, Yue-sheng;
Wu, Hong

Publication type:

Article

Improvement of growth and camptothecin yield by altering nitrogen source supply in cell suspension cultures ofCamptotheca acuminata.

Published in:

Biotechnology Letters, 2004, v. 26, n. 22, p. 1745, doi. 10.1007/s10529-004-4580-2

By:

Xue-Wu Pan;
Heng-Hao Xu;
Xin liu;
Xiang Gao;
Ying-Tang lu

Publication type:

Article

Bioreactor production of camptothecin by hairy root cultures of Ophiorrhiza pumila.

Published in:

Biotechnology Letters, 2002, v. 24, n. 5, p. 359, doi. 10.1023/A:1014568904957

By:

Sudo, Hiroshi;
Yamakawa, Takashi;
Yamazaki, Mami;
Aimi, Norio;
Saito, Kazuki

Publication type:

Article

A sensitive and rapid liquid chromatography tandem mass spectrometry method for quantitative determination of 7-ethyl-10-hydroxycamptothecin (SN-38) in human plasma containing liposome-based SN-38 (LE-SN38).

Published in:

Biomedical Chromatography, 2003, v. 17, n. 8, p. 493, doi. 10.1002/bmc.257

By:

Sumsullah Khan;
Ateeq Ahmad;
Imran Ahmad

Publication type:

Article

A bZIP transcription factor, CaLMF, mediated light-regulated camptothecin biosynthesis in Camptotheca acuminata.

Published in:

Tree Physiology, 2019, v. 39, n. 3, p. 372, doi. 10.1093/treephys/tpy106

By:

Chang, Chunhao;
Liu, Zhiwen;
Wang, Yanyan;
Tang, Zhonghua;
Yu, Fang

Publication type:

Article

Feasibility of biweekly combination chemotherapy with capecitabine, irinotecan, and oxaliplatin in patients with metastatic solid tumors: results of a two-step phase I trial: XELIRI and XELIRINOX.

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 3, p. 807, doi. 10.1007/s00280-011-1764-z

By:

Mazard, T.;
Ychou, M.;
Thezenas, S.;
Poujol, S.;
Pinguet, F.;
Thirion, A.;
Bleuse, J.;
Portales, F.;
Samalin, E.;
Assenat, E.

Publication type:

Article

Combining capecitabine, oxaliplatin, and gemcitabine (XELOXGEM) for colorectal carcinoma patients pretreated with irinotecan: a multicenter phase I/II trial.

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 1, p. 91, doi. 10.1007/s00280-011-1668-y

By:

Kim, Se;
Shin, Sang;
Kim, Sun;
Lee, Se;
Park, Young;
Park, Se;
Lee, Kyung;
Kim, Tae;
Hong, Yong;
Ahn, Joong

Publication type:

Article

Phase II study of combined belotecan and cisplatin as first-line chemotherapy in patients with extensive disease of small cell lung cancer.

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 1, p. 215, doi. 10.1007/s00280-011-1689-6

By:

Hong, Junshik;
Jung, Minkyu;
Kim, Yu;
Sym, Sun;
Kyung, Sun;
Park, Jinny;
Lee, Sang;
Park, Jeong;
Cho, Eun;
Jeong, Sung;
Shin, Dong;
Lee, Jae

Publication type:

Article

BACPTDP: a water-soluble camptothecin pro-drug with enhanced activity in hypoxic/acidic tumors.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 67, n. 4, p. 855, doi. 10.1007/s00280-010-1388-8

By:

Adams, David;
Waud, William;
Wani, Mansukh;
Manikumar, Govindarajan;
Flowers, James;
Driscoll, Timothy;
Morgan, Lee

Publication type:

Article

A phase I pharmacokinetics study of 9-nitrocamptothecin in patients with advanced solid tumors.

Published in:

2011

By:

Yan, Zhao;
Zhu, Zhongling;
Li, Kai;
Chen, Peng;
Wang, Liuchun;
Huang, Chun;
Xue, Jinhuai;
Liu, Meijun

Publication type:

Report

Synergistic interactions between aminoflavone, paclitaxel and camptothecin in human breast cancer cells.

Published in:

Cancer Chemotherapy & Pharmacology, 2010, v. 66, n. 3, p. 575, doi. 10.1007/s00280-009-1198-z

By:

Reinicke, Kathryn E.;
Kuffel, Mary J.;
Goetz, Matthew P.;
Ames, Matthew M.

Publication type:

Article

A water soluble prodrug of a novel camptothecin analog is efficacious against breast cancer resistance protein-expressing tumor xenografts.

Published in:

Cancer Chemotherapy & Pharmacology, 2010, v. 65, n. 2, p. 363, doi. 10.1007/s00280-009-1042-5

By:

Endo, Mika;
Miwa, Masanori;
Ura, Masako;
Tanimura, Hiromi;
Taniguchi, Kenji;
Miyazaki, Yoko;
Ohwada, Jun;
Tsukazaki, Masao;
Niizuma, Satoshi;
Murata, Takeshi;
Ozawa, Sawako;
Suda, Hitomi;
Ogawa, Kotaro;
Nanba, Eitaro;
Nagao, Shunsuke;
Shimma, Nobuo;
Yamada-Okabe, Hisafumi

Publication type:

Article

NSC606985, a novel camptothecin analog, induces apoptosis and growth arrest in prostate tumor cells.

Published in:

Cancer Chemotherapy & Pharmacology, 2009, v. 63, n. 2, p. 303, doi. 10.1007/s00280-008-0740-8

By:

Chen Tan;
Li-Qun Cai;
Wendy Wu;
Yaming Qiao;
Imperato-McGinley, Julianne;
Guo-Qiang Chen;
Yuan-Shan Zhu

Publication type:

Article

Phase II study of rubitecan in recurrent or metastatic head and neck cancer.

Published in:

Cancer Chemotherapy & Pharmacology, 2008, v. 62, n. 2, p. 209, doi. 10.1007/s00280-007-0592-7

By:

Caponigro, Francesco;
Cartenì, Giacomo;
Droz, Jean Pierre;
Milano, Amalia;
Davis, Wayne B.;
Pollard, Patricia

Publication type:

Article

Phase I study of vinorelbine and irinotecan in previously untreated patients with advanced non-small cell lung cancer.

Published in:

2008

By:

Tomonaga, Nanae;
Nakamura, Yoichi;
Soda, Hiroshi;
Nagashima, Seiji;
Nakano, Hirofumi;
Kinoshita, Akitoshi;
Fukuda, Masaaki;
Fukuda, Minoru;
Takatani, Hiroshi;
Soejima, Yoshifumi;
Oka, Mikio;
Kohno, Shigeru;
Nagasaki Thoracic Oncology Group

Publication type:

journal article

Genetic linkage of UGT1A7 and UGT1A9 polymorphisms to UGT1A1*6 is associated with reduced activity for SN-38 in Japanese patients with cancer.

Published in:

2007

By:

Fujita, Ken-ichi;
Ando, Yuichi;
Nagashima, Fumio;
Yamamoto, Wataru;
Eodo, Hisashi;
Araki, Kazuhiro;
Kodama, Keiji;
Miya, Toshimichi;
Narabayashi, Masaru;
Sasaki, Yasutsuna

Publication type:

journal article

Multicentre phase II study using increasing doses of irinotecan combined with a simplified LV5FU2 regimen in metastatic colorectal cancer.

Published in:

2007

By:

Duffour, Jacqueline;
Gourgou, Sophie;
Desseigne, Françoise;
Debrigode, Charles;
Mineur, Laurent;
Pinguet, Frédéric;
Poujol, Sylvain;
Chalbos, Patrick;
Bressole, Françoise;
Ychou, Marc

Publication type:

journal article

Phase II study of biweekly administration of docetaxel and irinotecan in patients with refractory or relapsed advanced non-small cell lung cancer.

Published in:

2007

By:

Hirose, Takashi;
Shirai, Takao;
Ishida, Hiroo;
Ando, Kohichi;
Sugiyama, Tomohide;
Kusumoto, Sojiro;
Hosaka, Takamichi;
Nakashima, Masanao;
Ohmori, Tohru;
Adachi, Mitsuru

Publication type:

journal article

A phase II trial of cisplatin and irinotecan alternating with doxorubicin, cyclophosphamide and etoposide in previously untreated patients with extensive-disease small-cell lung cancer.

Published in:

2007

By:

Tabata, Masahiro;
Kiura, Katsuyuki;
Okimoto, Niro;
Segawa, Yoshihiko;
Shinkai, Tetsu;
Yonei, Toshiro;
Kuyama, Shoichi;
Harita, Shingo;
Hotta, Katsuyuki;
Ueoka, Hiroshi;
Tanimoto, Mitsune

Publication type:

journal article

Irinotecan-cisplatin interactions assessed in cell-based screening assays: cytotoxicity, drug accumulation and DNA adduct formation in an NSCLC cell line.

Published in:

2007

By:

Zastre, Jason;
Anantha, Malathi;
Ramsay, Euan;
Bally, Marcel

Publication type:

journal article

A phase II study of weekly irinotecan as first-line therapy for patients with metastatic pancreatic cancer.

Published in:

2007

By:

Ueno, Hideki;
Okusaka, Takuji;
Funakoshi, Akihiro;
Ishii, Hiroshi;
Yamao, Kenji;
Ishikawa, Osamu;
Ohkawa, Shinichi;
Saitoh, Soh

Publication type:

journal article

Phase I and pharmacologic study of irinotecan and amrubicin in advanced non-small cell lung cancer.

Published in:

2007

By:

Yanaihara, Tomoko;
Yokoba, Masanori;
Onoda, Sayaka;
Yamamoto, Michiko;
Ryuge, Shinichiro;
Hagiri, Shintaro;
Katagiri, Masato;
Wada, Mayuko;
Mitsufuji, Hisashi;
Kubota, Masaru;
Arai, Susumu;
Kobayashi, Hirosuke;
Yanase, Nobuo;
Abe, Tadashi;
Masuda, Noriyuki

Publication type:

journal article

Adsorption of irinotecan onto oral adsorbent AST-120 (Kremezin<sup>TM</sup>) for preventing delayed diarrhea.

Published in:

Cancer Chemotherapy & Pharmacology, 2007, v. 59, n. 3, p. 321, doi. 10.1007/s00280-006-0273-y

By:

Hidaka, Muneaki;
Yamasaki, Keishi;
Okumura, Manabu;
Ogikubo, Tetsuya;
Iwakiri, Tomomi;
Setoguchi, Nao;
Nishida, Kentaro;
Nagai, Kimihiro;
Ikenoue, Tsuyomu;
Arimori, Kazuhiko

Publication type:

Article

Reproductive toxicity evaluation of a new camptothecin anticancer agent, CKD-602, in pregnant/lactating female rats and their offspring.

Published in:

Cancer Chemotherapy & Pharmacology, 2007, v. 59, n. 3, p. 383, doi. 10.1007/s00280-006-0290-x

By:

Chung, Moon-Koo;
Kim, Choong-Yong;
Kim, Jong-Choon

Publication type:

Article

Irinotecan changes gene expression in the small intestine of the rat with breast cancer.

Published in:

2007

By:

Bowen, Joanne M;
Gibson, Rachel J;
Cummins, Adrian G;
Tyskin, Anna;
Keefe, Dorothy M K

Publication type:

journal article

A phase II trial of weekly fractionated irinotecan and cisplatin for advanced gastric cancer.

Published in:

2007

By:

Jeung, Hei-Cheul;
Rha, Sun Young;
Noh, Sung Hoon;
Roh, Jae Kyung;
Chung, Hyun Cheol

Publication type:

journal article

Adsorption of irinotecan onto oral adsorbent AST-120 (Kremezin) for preventing delayed diarrhea.

Published in:

2007

By:

Hidaka, Muneaki;
Yamasaki, Keishi;
Okumura, Manabu;
Ogikubo, Tetsuya;
Iwakiri, Tomomi;
Setoguchi, Nao;
Nishida, Kentaro;
Nagai, Kimihiro;
Ikenoue, Tsuyomu;
Arimori, Kazuhiko

Publication type:

journal article

BCRP/ABCG2 levels account for the resistance to topoisomerase I inhibitors and reversal effects by gefitinib in non-small cell lung cancer.

Published in:

2006

By:

Nagashima, Seiji;
Soda, Hiroshi;
Oka, Mikio;
Kitazaki, Takeshi;
Shiozawa, Ken;
Nakamura, Yoichi;
Takemura, Masaaki;
Yabuuchi, Hikaru;
Fukuda, Minoru;
Tsukamoto, Kazuhiro;
Kohno, Shigeru

Publication type:

journal article

Irinotecan in combination with thalidomide in patients with advanced solid tumors: a clinical study with pharmacodynamic and pharmacokinetic evaluation.

Published in:

2006

By:

Allegrini, Giacomo;
Di Paolo, Antonello;
Cerri, Elisa;
Cupini, Samanta;
Amatori, Federica;
Masi, Gianluca;
Danesi, Romano;
Marcucci, Lorenzo;
Bocci, Guido;
del Tacca, Mario;
Falcone, Alfredo

Publication type:

journal article

Optimal antidiarrhea treatment for antitumor agent irinotecan hydrochloride (CPT-11)-induced delayed diarrhea.

Published in:

2006

By:

Takasuna, K.;
Hagiwara, T.;
Watanabe, K.;
Onose, S.;
Yoshida, S.;
Kumazawa, E.;
Nagai, E.;
Kamataki, T.

Publication type:

journal article

Novel fluoro-substituted camptothecins: in vivo antitumor activity, reduced gastrointestinal toxicity and pharmacokinetic characterization.

Published in:

2006

By:

Rose, William C.;
Marathe, Punit H.;
Jang, Graham R.;
Monticello, Thomas M.;
Balasubramanian, Balu N.;
Long, Byron;
Fairchild, Craig R.;
Wall, Monroe E.;
Wani, Mansukh C.

Publication type:

journal article

Pharmacokinetics and biodistribution of the camptothecin–polymer conjugate IT-101 in rats and tumor-bearing mice.

Published in:

Cancer Chemotherapy & Pharmacology, 2006, v. 57, n. 5, p. 654, doi. 10.1007/s00280-005-0091-7

By:

Schluep, Thomas;
Jianjun Cheng;
Khin, Kay T.;
Davis, Mark E.

Publication type:

Article

Clinical and pharmacokinetic study evaluating the effect of food on the disposition of 9-nitrocamptothecin and its 9-aminocamptothecin metabolite in patients with solid tumors.

Published in:

Cancer Chemotherapy & Pharmacology, 2006, v. 57, n. 5, p. 631, doi. 10.1007/s00280-005-0084-6

By:

Zamboni, William C.;
Goel, Sanjay;
Iqbal, Tahir;
Parise, Robert A.;
Strychor, Sandra;
Repinski, Trisha V. W.;
Egorin, Merrill J.;
Mani, Sridhar

Publication type:

Article

Minimal clinical benefit of single agent Orathecin (Rubitecan) in heavily pretreated metastatic breast cancer.

Published in:

Cancer Chemotherapy & Pharmacology, 2006, v. 57, n. 4, p. 540, doi. 10.1007/s00280-005-0064-x

By:

Chedid, Silwan;
Rivera, Edgardo;
Frye, Debbie K.;
Ibrahim, Nuhad;
Esteva, Francisco;
Valero, Vicente;
Hortobagyi, Gabriel;
Mettinger, Karl L.;
Cristofanilli, Massimo

Publication type:

Article

Camptothecin analogs with enhanced activity against human breast cancer cells. II. Impact of the tumor pH gradient.

Published in:

Cancer Chemotherapy & Pharmacology, 2006, v. 57, n. 2, p. 145, doi. 10.1007/s00280-005-0008-5

By:

Adams, David J.;
Wahl, Miriam L.;
Flowers, James L.;
Sen, Banalata;
Colvin, Michael;
Dewhirst, Mark W.;
Manikumar, Govindarajan;
Wani, Mansukh C.

Publication type:

Article

Camptothecin analogs with enhanced activity against human breast cancer cells. I. Correlation of potency with lipophilicity and persistence in the cleavage complex.

Published in:

Cancer Chemotherapy & Pharmacology, 2006, v. 57, n. 2, p. 135, doi. 10.1007/s00280-005-0007-6

By:

Adams, David J.;
da Silva, Mateus Webba;
Flowers, James L.;
Kohlhagen, Glenda;
Pommier, Yves;
Colvin, O. Michael;
Manikumar, Govindarajan;
Wani, Mansukh C.

Publication type:

Article

Sequential administration of irinotecan and cytarabine in the treatment of relapsed and refractory acute myeloid leukemia.

Published in:

2006

By:

Minderman, Hans;
O'Loughlin, Kieran;
Smith, Patrick;
Pendyala, Lakshmi;
Greco, William;
Sweeney, Kimberly;
Ford, Laurie;
Wetzler, Meir;
Baer, Maria;
O'Loughlin, Kieran L;
Smith, Patrick F;
Greco, William R;
Sweeney, Kimberly G;
Ford, Laurie A;
Baer, Maria R

Publication type:

journal article

Irinotecan combined with docetaxel in pre-treated metastatic breast cancer patients: a phase II study.

Published in:

2005

By:

Stathopoulos, G. P.;
Tsavdaridis, D.;
Malamos, N. A.;
Rigatos, S. K.;
Kosmas, Ch.;
Pergantas, N.;
Stathopoulos, J. G.;
Xynotroulas, J.

Publication type:

journal article

Spectrophotometric investigation of the chemical compatibility of the anticancer drugs irinotecan-HCl and epirubicin-HCl in the same infusion solution.

Published in:

2005

By:

Ozdemir, Filiz Arioz;
Anilanmert, Beril;
Pekin, Mursit

Publication type:

journal article

S-phase modulation by irinotecan: pilot studies in advanced solid tumors.

Published in:

2005

By:

Ramnath, N.;
Khushalani, N.;
Toth, K.;
Litwin, A. M.;
Intengan, M. E.;
Slocum, H. K.;
Pendyala, L.;
Smith, P. F.;
Stewart, C. C.;
Hoffman, J. L.;
Javle, M. M.;
Berdzik, J.;
Creaven, P. J.;
Rustum, Y. M.

Publication type:

journal article

Phase I study of etoposide, cisplatin and irinotecan triplet in patients with advanced-stage small-cell lung cancer.

Published in:

2005

By:

Briasoulis, E.;
Samantas, E.;
Kalofonos, H.;
Skarlos, D.;
Makatsoris, T.;
Christodoulou, C.;
Fountzilas, G.;
Bamias, A.;
Dimopoulos, M.A.;
Kosmidis, P.;
Pavlidis, N.

Publication type:

journal article

Phase I clinical and pharmacokinetic trial of docetaxel and irinotecan administered on a weekly schedule.

Published in:

2005

By:

Garcia, Agustin A.;
Pujari, Mahesh;
Jeffers, Susan;
Iqbal, Syma;
Lenz, Heinz-Josef;
Beringer, Paul;
Louie, Stan

Publication type:

journal article

A phase I, dose-finding study of irinotecan (CPT-11) short i.v. infusion combined with fixed dose of 5-fluorouracil (5-FU) protracted i.v. infusion in adult patients with advanced solid tumours.

Published in:

2005

By:

Sastre, Javier;
Paz-Ares, Luis;
Carcas, Antonio;
Alfonso, Rosario;
Grávalos, Cristina;
Frías, Jesus;
Guerra, Pedro;
Pronk, Linda;
Cortés-Funes, Hernán;
Díaz-Rubio, Eduardo;
Grávalos, Cristina;
Frías, Jesus;
Cortés-Funes, Hernán;
Díaz-Rubio, Eduardo

Publication type:

journal article

Gefitinib ("Iressa", ZD1839) inhibits SN38-triggered EGF signals and IL-8 production in gastric cancer cells.

Published in:

2005

By:

Kishida, Osamu;
Miyazaki, Yoshiji;
Murayama, Yoko;
Ogasa, Miyuki;
Miyazaki, Tamana;
Yamamoto, Takahiro;
Watabe, Kenji;
Tsutsui, Shusaku;
Kiyohara, Tatsuya;
Shimomura, Iichiro;
Shinomura, Yasuhisa

Publication type:

journal article

A possible mechanism for the long-lasting antitumor effect of the macromolecular conjugate DE-310: mediation by cellular uptake and drug release of its active camptothecin analog DX-8951.

Published in:

2005

By:

Ochi, Yusuke;
Shiose, Yoshinobu;
Kuga, Hiroshi;
Kumazawa, Eiji

Publication type:

journal article