Works matching DE "BRUTON tyrosine kinase"

Results: 848

Efficacy of individualized orelabrutinib-based regimens in relapsed or refractory central nervous system lymphoma.

Published in:

Frontiers in Neurology, 2025, p. 1, doi. 10.3389/fneur.2025.1570224

By:

Wu, Yuchen;
Sun, Xuefei;
Lv, Liwei;
Cui, Qu;
Qian, Jun;
Xing, Ruixian;
Bai, Xueyan;
Chen, Yuedan;
Liu, Qing;
Lai, Wenyuan;
Gao, Chunji;
Sun, Shengjun;
Ji, Nan;
Liu, Yuanbo

Publication type:

Article

Fixed‐duration acalabrutinib combinations in patients with untreated CLL lead to improved progression‐free survival.

Published in:

Cancer (0008543X), 2025, v. 131, n. 12, p. 1, doi. 10.1002/cncr.35898

By:

Nierengarten, Mary Beth

Publication type:

Article

First Drug for Nonrelapsing MS Progression on the Horizon.

Published in:

JAMA: Journal of the American Medical Association, 2025, v. 333, n. 22, p. 1944, doi. 10.1001/jama.2025.6153

By:

Anderer, Samantha

Publication type:

Article

Beyond BCL2 (B cell lymphoma) and BTK (Bruton tyrosine kinase) inhibitors: novel agents and resistance mechanisms for chronic lymphocytic leukemia.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02947-9

By:

Hays, Priya

Publication type:

Article

Marginal Zone Lymphoma: Treatment Update With a Focus on Systemic Approaches.

Published in:

Hematological Oncology, 2025, v. 43, p. 1, doi. 10.1002/hon.70079

By:

Smith, Sonali M.

Publication type:

Article

First Line Therapy in Mantle Cell Lymphoma—The Role of BTKi in the Initial Treatment of Transplant‐Eligible and ‐Ineligible Patients.

Published in:

Hematological Oncology, 2025, v. 43, p. 1, doi. 10.1002/hon.70073

By:

Silkenstedt, E.;
Dreyling, M.

Publication type:

Article

Diagnosis and Management of Waldenstrom's Macroglobulinemia.

Published in:

Hematological Oncology, 2025, v. 43, p. 1, doi. 10.1002/hon.70071

By:

Treon, Steven P.;
Sarosiek, Shayna;
Castillo, Jorge J.

Publication type:

Article

Advances in the Management of Relapsed/Refractory CLL and Richter Transformation.

Published in:

Hematological Oncology, 2025, v. 43, p. 1, doi. 10.1002/hon.70064

By:

Javidi‐Sharifi, Nathalie;
Davids, Matthew S.

Publication type:

Article

Rilzabrutinib for the Treatment of Immune Thrombocytopenia.

Published in:

European Journal of Haematology, 2025, v. 115, n. 1, p. 4, doi. 10.1111/ejh.14425

By:

Labanca, Caterina;
Martino, Enrica Antonia;
Vigna, Ernesto;
Bruzzese, Antonella;
Mendicino, Francesco;
Caridà, Giulio;
Lucia, Eugenio;
Olivito, Virginia;
Manicardi, Veronica;
Amodio, Nicola;
Neri, Antonino;
Morabito, Fortunato;
Gentile, Massimo

Publication type:

Article

Unleashing the Power of Covalent Drugs for Protein Degradation.

Published in:

Medicinal Research Reviews, 2025, v. 45, n. 4, p. 1045, doi. 10.1002/med.22101

By:

Fu, Meng‐Jie;
Jin, Hang;
Wang, Shao‐Peng;
Shen, Liang;
Liu, Hong‐Min;
Liu, Ying;
Zheng, Yi‐Chao;
Dai, Xing‐Jie

Publication type:

Article

Bruton's Tyrosine Kinase: A Potential Novel Target for Neurological Disorders.

Published in:

Physiological Research, 2025, v. 74, n. 2, p. 233, doi. 10.33549/physiolres.935494

By:

DAS, Debanjan;
GHOSH, Arijit;
GRECO, Denise;
MICHALIČKOVÁ, Danica;
SLANAŘ, Ondřej

Publication type:

Article

Investigation of the mechanism of hypertension caused by BTKi in the treatment of hematologic diseases.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1585061

By:

Xu, Jiayi;
Lin, Junling;
Gan, Haojian;
He, Qingjian;
Wang, WenJuan;
Liu, Yuanhua

Publication type:

Article

The role of microglia in multiple sclerosis: implications for treatment with Bruton's tyrosine kinase inhibitors.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1495529

By:

Vermersch, Patrick;
Airas, Laura;
Berger, Thomas;
Deisenhammer, Florian;
Grigoriadis, Nikolaos;
Hartung, Hans-Peter;
Magyari, Melinda;
Popescu, Veronica;
Pozzilli, Carlo;
Pugliatti, Maura;
Van Wijmeersch, Bart;
Zakaria, Magd;
Oreja-Guevara, Celia

Publication type:

Article

Abstracts.

Published in:: FEBS Open Bio, 2025, v. 15, p. 14, doi. 10.1002/2211-5463.70030
Publication type:: Article

Anaphylaxie: Das Potenzial von BTK-Inhibitoren bei der Behandlung von Nahrungsmittelallergien.

Published in:

Kompass Dermatologie, 2024, v. 12, n. 4, p. 214, doi. 10.1159/000542071

By:

Wedi, Bettina

Publication type:

Article

Development of a Fast and Sensitive UPLC–MS/MS Analytical Methodology for Fenebrutinib Estimation in Human Liver Microsomes: In Vitro and In Silico Metabolic Stability Evaluation.

Published in:

Separations (2297-8739), 2023, v. 10, n. 5, p. 302, doi. 10.3390/separations10050302

By:

Attwa, Mohamed W.;
Alsibaee, Aishah M.;
Aljohar, Haya I.;
Abdelhameed, Ali S.;
Kadi, Adnan A.

Publication type:

Article

Bioactivation and reactivity research advances – 2021 year in review.

Published in:

Drug Metabolism Reviews, 2022, v. 54, n. 3, p. 246, doi. 10.1080/03602532.2022.2097254

By:

Jackson, Klarissa D.;
Argikar, Upendra A.;
Cho, Sungjoon;
Crouch, Rachel D.;
Driscoll, James P.;
Heck, Carley J. S.;
King, Lloyd;
Maw, Hlaing;
Miller, Grover P.;
Seneviratne, Herana Kamal;
Wang, Shuai;
Wei, Cong;
Zhang, Donglu;
Khojasteh, S. Cyrus;
Garrido, Claudia;
Leimkuhler, Silke;
Sun, Chen;
Zhao, Huimin;
Li, Wei;
Jia, Yudi

Publication type:

Article

BTK acts as a modulator of the response to imatinib in chronic myeloid leukemia.

Published in:

Oncology Letters, 2024, v. 28, n. 3, p. N.PAG, doi. 10.3892/ol.2024.14557

By:

Schmidlechner, Lena;
Nagel, Inga;
Vater, Inga;
Cascorbi, Ingolf;
Kaehler, Meike

Publication type:

Article

BTK inhibitor combined with anti-PD-1 monoclonal antibody for the treatment of CD20-negative primary central nervous system lymphoma: A case report.

Published in:

2023

By:

Feng, Lan;
Gao, Xiaohui;
Jiao, Zhiyun;
Wang, Zheng;
Min, Fenglin

Publication type:

Case Study

Clues to management of neonatally diagnosed BTK deficiency.

Published in:

Pediatric Allergy & Immunology, 2016, v. 27, n. 4, p. 428, doi. 10.1111/pai.12549

By:

Deyà‐Martínez, Angela;
Esteve‐Sole, Ana;
Giner, Maria Teresa;
Aróstegui, Juan I.;
Ruiz‐Ortiz, Estíbaliz;
Yagüe, Jordi;
Juan, Manel;
Plaza, Ana Maria;
Alsina, Laia

Publication type:

Article

Simulation-Based Research on Phytoconstituents of Embelia ribes Targeting Proteins with Pathophysiological Implications in Rheumatoid Arthritis.

Published in:

Life (2075-1729), 2023, v. 13, n. 7, p. 1467, doi. 10.3390/life13071467

By:

Radu, Andrei-Flavius;
Negru, Paul Andrei;
Radu, Ada;
Tarce, Alexandra Georgiana;
Bungau, Simona Gabriela;
Bogdan, Mihaela Alexandra;
Tit, Delia Mirela;
Uivaraseanu, Bogdan

Publication type:

Article

Pharmacology of drugs used in autoimmune dermatopathies in cats and dogs: A narrative review.

Published in:

Veterinary Dermatology, 2024, v. 35, n. 4, p. 453, doi. 10.1111/vde.13253

By:

Tham, Heng L.;
Davis, Jennifer L.

Publication type:

Article

State‐of‐the‐art review of human autoimmune blistering diseases (AIBD).

Published in:

Veterinary Dermatology, 2021, v. 32, n. 6, p. 524, doi. 10.1111/vde.13008

By:

Zeng, Faith A.P.;
Murrell, Dedee F.

Publication type:

Article

Bilateral Intraocular Involvement of Recurrent Mantle Cell Lymphoma with Remission of Pseudo-Uveitis and Secondary Glaucoma After Switching Treatment to Ibrutinib: A Case Report.

Published in:

Ocular Immunology & Inflammation, 2025, v. 33, n. 3, p. 488, doi. 10.1080/09273948.2024.2417804

By:

Takahashi, Tatsuhiro;
Matsuo, Masato;
Mochizuki, Kiyofumi;
Sakaguchi, Hirokazu

Publication type:

Article

Ibrutinib-Related Uveitis: A Case Series from Two Tertiary Centres in the United Kingdom.

Published in:

Ocular Immunology & Inflammation, 2024, v. 32, n. 10, p. 2583, doi. 10.1080/09273948.2024.2396007

By:

Ibrahim, Hagar;
Chean, Chung Shen;
Kalakonda, Anita J. M.;
Kwan, Jennifer;
Kumar, Periyasamy;
Williams, Stella;
Beare, Nicholas A. V.

Publication type:

Article

Ibrutinib-Related Uveitis in Non-Hodgkin Lymphoma Patients: A Case Report and Literature Review.

Published in:

2024

By:

Mendez, Rafael;
Pineda-Sierra, Juan Sebastián;
Romero-Santos, Sofia;
Cifuentes-González, Carlos;
Bonaccorso, Silvina;
Couto, Cristobal;
Schlaen, Ariel;
Mejía-Salgado, Germán;
de-la-Torre, Alejandra

Publication type:

Case Study

Hyperviscosity Syndrome Induced Bilateral Visual and Auditory Impairment in Therapy Resistant Waldenström Macroglobulinemia with MYD88 and CXCR4 Mutations.

Published in:

2023

By:

Plante, Marie M;
Kimbrough, ErinMarie O;
Agarwal, Amit K;
Jiang, Liuyan;
Bourgeois, Kirk;
Stamper, Greta C;
Stewart, Michael W;
Tun, Han W

Publication type:

Case Study

Chronic Inflammatory Demyelinating Polyradiculoneuropathy: Current Therapeutic Approaches and Future Outlooks.

Published in:

ImmunoTargets & Therapy, 2024, v. 13, p. 99, doi. 10.2147/ITT.S388151

By:

Rajabally, Yusuf A

Publication type:

Article

A novel double hemizygous BTK mutation in a boy presenting with Pseudomonas skin abscesses.

Published in:

Clinical & Experimental Dermatology, 2022, v. 47, n. 6, p. 1218, doi. 10.1111/ced.15125

By:

Guler, Tugba;
Emiroglu, Melike;
Duymus, Fahrettin;
Marzioglu Ozdemir, Ebru;
Artac, Hasibe

Publication type:

Article

Skin abscesses, X‐linked agammaglobulinaemia and spastic paraplegias in a male patient.

Published in:

Clinical & Experimental Dermatology, 2022, v. 47, n. 3, p. 617, doi. 10.1111/ced.15013

By:

Zhang, C. C.;
Chen, Z. M.;
Chen, H.

Publication type:

Article

Haemorrhagic bullae and purpura associated with the Bruton tyrosine kinase inhibitor ibrutinib.

Published in:

Clinical & Experimental Dermatology, 2022, v. 47, n. 2, p. 488, doi. 10.1111/ced.14966

By:

Steele, L.;
George, C.;
Cerio, R.;
O'Toole, E. A.

Publication type:

Article

Chronic lymphocytic leukaemia‐associated insect bite‐like reaction responding to ibrutinib, an immunomodulatory Bruton tyrosine kinase inhibitor.

Published in:

Clinical & Experimental Dermatology, 2021, v. 46, n. 8, p. 1569, doi. 10.1111/ced.14761

By:

Wimalachandra, M.;
Basu, T. N.;
Salisbury, J.;
Attard, N;
Calonje, E.;
Patten, P. E. M.

Publication type:

Article

Resisting the Resistance: Navigating BTK Mutations in Chronic Lymphocytic Leukemia (CLL).

Published in:

Genes, 2023, v. 14, n. 12, p. 2182, doi. 10.3390/genes14122182

By:

Chirino, Alexandra;
Montoya, Skye;
Safronenka, Anita;
Taylor, Justin

Publication type:

Article

Taking the Next Step in Double Refractory Disease: Current and Future Treatment Strategies for Chronic Lymphocytic Leukemia.

Published in:

OncoTargets & Therapy, 2024, v. 17, p. 181, doi. 10.2147/OTT.S443924

By:

Hayama, Manabu;
Riches, John C

Publication type:

Article

Targeted Treatment of Chronic Lymphocytic Leukemia: Clinical Utility of Acalabrutinib.

Published in:

OncoTargets & Therapy, 2021, v. 14, p. 5507, doi. 10.2147/OTT.S303060

By:

Vitale, Candida;
Gibbons, Jamie Lynn;
Ferrajoli, Alessandra

Publication type:

Article

The conundrum of below the knee (BTK) drug delivery.

Published in:

Vascular Medicine, 2023, v. 28, n. 6, p. 581, doi. 10.1177/1358863X231204626

By:

Schneider, Peter A

Publication type:

Article

Intention to treat: The management of connective tissue disease‐related immune thrombocytopenia.

Published in:

International Journal of Rheumatic Diseases, 2023, v. 26, n. 10, p. 1885, doi. 10.1111/1756-185X.14811

By:

Fu, Yakai;
Zhao, Liling;
Ye, Shuang

Publication type:

Article

Efficacy and Safety of Syk and BTK Inhibitors in Immune Thrombocytopenia: A Comprehensive Review of Emerging Evidence.

Published in:

Mediators of Inflammation, 2025, p. 1, doi. 10.1155/mi/5578929

By:

Heidari, Amirhossein;
Mazid, Amirhossein Shahbazi;
Behroozfar, Mohammad;
Ghotbi, Negar;
Fathabadi, Fatemeh;
Eghbali, Sara;
Heidari, Nazila;
Tsuji, Fumio

Publication type:

Article

Evobrutinib pathway to its major metabolite M463-2 and insights from a biotransformation and DDI perspective.

Published in:

Xenobiotica, 2023, v. 53, n. 8/9, p. 547, doi. 10.1080/00498254.2023.2272180

By:

Scheible, Holger;
Schieferstein, Hanno;
Schmidt, Ralf;
Pusecker, Klaus;
Gradhand, Ulrike;
Gopalakrishnan, Sathej;
Iqbal, Khalid;
Dong, Jennifer;
Jones, Reinaldo;
Meli, Claudia;
Bolleddula, Jayaprakasam;
Dyroff, Martin;
Georgi, Katrin

Publication type:

Article

Time matters – in vitro cellular disposition kinetics help rationalizing cellular potency disconnects.

Published in:

Xenobiotica, 2022, v. 52, n. 8, p. 878, doi. 10.1080/00498254.2022.2130837

By:

Poller, Birk;
Werner, Sophie;
Domange, Norbert;
Mettler, Lina;
Stein, Richard R.;
Loretan, Jacqueline;
Wartmann, Markus;
Faller, Bernard;
Huth, Felix

Publication type:

Article

The relation between BTK expression and iron accumulation of myeloid cells in multiple sclerosis.

Published in:

Brain Pathology, 2024, v. 34, n. 5, p. 1, doi. 10.1111/bpa.13240

By:

Steinmaurer, Anja;
Riedl, Christian;
König, Theresa;
Testa, Giulia;
Köck, Ulrike;
Bauer, Jan;
Lassmann, Hans;
Höftberger, Romana;
Berger, Thomas;
Wimmer, Isabella;
Hametner, Simon

Publication type:

Article

Honing in on magnetic resonance imaging predictors of multiple sclerosis pathology.

Published in:

Brain Pathology, 2023, v. 33, n. 6, p. 1, doi. 10.1111/bpa.13209

By:

Schmierer, Klaus

Publication type:

Article

Therapeutic potential and recent progression of BTK inhibitors against rheumatoid arthritis.

Published in:

Chemical Biology & Drug Design, 2024, v. 104, n. 1, p. 1, doi. 10.1111/cbdd.14582

By:

Paliwal, Swati;
Bawa, Sandhya;
Shalmali, Nishtha;
Tonk, Rajiv K.

Publication type:

Article

Herpes Zoster and Varicella Encephalitis Following the Recombinant Zoster Vaccine.

Published in:

2024

By:

Pane, Mallory;
Harrell, Catherine;
Pickell, Stuart C.

Publication type:

Case Study

CD38-mediated Inhibition of Bruton's Tyrosine Kinase in Macrophages Prevents Endotoxemic Lung Injury.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2022, v. 66, n. 2, p. 183, doi. 10.1165/rcmb.2021-0272OC

By:

Farahany, Joseph;
Yoshikazu Tsukasaki;
Mukhopadhyay, Amitabha;
Mittal, Manish;
Nepal, Saroj;
Tiruppathi, Chinnaswamy;
Malik, Asrar B.

Publication type:

Article

Hepatitis B virus reactivation in seronegative occult hepatitis B patient receiving ibrutinib therapy.

Published in:

Virology Journal, 2023, v. 20, n. 1, p. 1, doi. 10.1186/s12985-023-02140-w

By:

Lam, Lok-Ka;
Chan, Thomas Sau Yan;
Hwang, Yu-Yan;
Mak, Lung-Yi;
Seto, Wai-Kay;
Kwong, Yok-Lam;
Yuen, Man-Fung

Publication type:

Article

New Frontiers in Multiple Sclerosis Treatment: From Targeting Costimulatory Molecules to Bispecific Antibodies.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 8, p. 3880, doi. 10.3390/ijms26083880

By:

Reidy, Megan;
Khan, Meerah;
Mills, Elizabeth A.;
Wu, Qi;
Garton, Josh;
Draayer, Dean E.;
Zahoor, Insha;
Giri, Shailendra;
Axtell, Robert C.;
Mao-Draayer, Yang

Publication type:

Article

Double Strike in Chronic Lymphocytic Leukemia—The Combination of BTK and BCL2 Inhibitors in Actual and Future Clinical Practice.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 7, p. 3193, doi. 10.3390/ijms26073193

By:

Zygmunciak, Przemyslaw;
Dancewicz, Hanna;
Stróżna, Katarzyna;
Błażowska, Olga;
Bieliński, Krzysztof;
Robak, Tadeusz;
Puła, Bartosz

Publication type:

Article

Hematological Malignancies: Molecular Mechanisms and Therapy.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 6, p. 2438, doi. 10.3390/ijms26062438

By:

Bouziana, Stella

Publication type:

Article

Targeting Tumor Microenvironment Interactions in Chronic Lymphocytic Leukemia Using Leukotriene Inhibitors.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 5, p. 2209, doi. 10.3390/ijms26052209

By:

Sadeghi, Laia;
Merrien, Magali;
Björkholm, Magnus;
Österborg, Anders;
Sander, Birgitta;
Claesson, Hans-Erik;
Wright, Anthony P. H.

Publication type:

Article