Works matching DE "BROMODOMAINS"

Results: 28

Large-scale analysis of water stability in bromodomain binding pockets with grand canonical Monte Carlo.

Published in:

Communications Chemistry, 2018, v. 1, n. 1, p. N.PAG, doi. 10.1038/s42004-018-0019-x

By:

Aldeghi, Matteo;
Ross, Gregory A.;
Bodkin, Michael J.;
Essex, Jonathan W.;
Knapp, Stefan;
Biggin, Philip C.

Publication type:

Article

Phase 1 Study of Molibresib (GSK525762), a Bromodomain and Extra-Terminal Domain Protein Inhibitor, in NUT Carcinoma and Other Solid Tumors.

Published in:

JNCI Cancer Spectrum, 2020, v. 4, n. 2, p. 1, doi. 10.1093/jncics/pkz093

By:

Piha-Paul, Sarina A;
Hann, Christine L;
French, Christopher A;
Cousin, Sophie;
Braña, Irene;
Cassier, Phillippe A;
Moreno, Victor;
Bono, Johann S de;
Harward, Sara Duckworth;
Ferron-Brady, Geraldine;
Barbash, Olena;
Wyce, Anastasia;
Wu, Yuehui;
Horner, Thierry;
Annan, Meg;
Parr, Nigel J;
Prinjha, Rabinder K;
Carpenter, Christopher L;
Hilton, John;
Hong, David S

Publication type:

Article

How Much Can We Bet on Activity of BET Inhibitors Beyond NUT–Midline Carcinoma?

Published in:

2020

By:

Martin-Romano, Patricia;
Baldini, Capucine;
Postel-Vinay, Sophie

Publication type:

Editorial

Inducing DNA damage through R-loops to kill cancer cells.

Published in:

Molecular & Cellular Oncology, 2021, v. 8, n. 1, p. 1, doi. 10.1080/23723556.2020.1848233

By:

Lam, Fred C.;
Kong, Yi Wen;
Yaffe, Michael B.

Publication type:

Article

PBRM1 suppresses tumor growth as a novel p53 acetylation reader.

Published in:

Molecular & Cellular Oncology, 2020, v. 7, n. 3, p. 1, doi. 10.1080/23723556.2020.1729680

By:

Cai, Weijia;
Su, Liya;
Yang, Haifeng

Publication type:

Article

Mitochondrial fission promotes self-renewal and tumorigenic potential in prostate cancer.

Published in:

2019

By:

Civenni, Gianluca;
Carbone, Giuseppina M.;
Catapano, Carlo V.

Publication type:

Opinion

DREAM target reactivation by core transcriptional regulators supports neuroblastoma growth.

Published in:

Molecular & Cellular Oncology, 2019, v. 6, n. 2, p. 1, doi. 10.1080/23723556.2019.1565470

By:

Decaesteker, Bieke;
De Preter, Katleen;
Speleman, Frank

Publication type:

Article

BET inhibitor suppresses migration of human hepatocellular carcinoma by inhibiting SMARCA4.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-91284-2

By:

Choi, Hae In;
An, Ga Yeong;
Baek, Mina;
Yoo, Eunyoung;
Chai, Jin Choul;
Lee, Young Seek;
Jung, Kyoung Hwa;
Chai, Young Gyu

Publication type:

Article

Author Correction: Bromodomain protein Brd3 promotes Ifnb1 transcription via enhancing IRF3/p300 complex formation and recruitment to Ifnb1 promoter in macrophages.

Published in:

2020

By:

Ren, Wenhui;
Wang, Chunmei;
Wang, Qinlan;
Zhao, Dezhi;
Zhao, Kai;
Sun, Donghao;
Liu, Xingguang;
Han, Chaofeng;
Hou, Jin;
Li, Xia;
Zhang, Qian;
Cao, Xuetao;
Li, Nan

Publication type:

Correction Notice

USP24 stabilizes bromodomain containing proteins to promote lung cancer malignancy.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-78000-2

By:

Wang, Shao-An;
Young, Ming-Jer;
Jeng, Wen-Yih;
Liu, Chia-Yu;
Hung, Jan-Jong

Publication type:

Article

Cytotoxic activity of bromodomain inhibitor NVS-CECR2-1 on human cancer cells.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-73500-7

By:

Park, Seul Gi;
Lee, Daye;
Seo, Hye-Ran;
Lee, Shin-Ai;
Kwon, Jongbum

Publication type:

Article

Design of thienopyranone-based BET inhibitors that bind multiple synthetic lethality targets.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-68964-6

By:

Vann, Kendra R.;
Pal, Dhananjaya;
Morales, Guillermo A.;
Burgoyne, Adam M.;
Durden, Donald L.;
Kutateladze, Tatiana G.

Publication type:

Article

Reply to Chen : BET Signaling: A Novel Therapeutic Target for Pulmonary Hypertension?

Published in:

2020

By:

Provencher, Steeve;
Boucherat, Olivier;
Berger, Rolf M F;
Goumans, Marie-José;
Bonnet, Sébastien

Publication type:

Letter

BET Signaling: A Novel Therapeutic Target for Pulmonary Hypertension?

Published in:

2020

By:

Lingdan Chen;
Chunli Liu;
Wenju Lu;
Tao Wang;
Chen, Lingdan;
Liu, Chunli;
Lu, Wenju;
Wang, Tao

Publication type:

Letter

EpiHope for the Treatment of Pulmonary Arterial Hypertension: Selective versus Nonselective BET Inhibition.

Published in:

2019

By:

Pullamsetti, Soni Savai;
de Jesus Perez, Vinicio A.

Publication type:

Letter

Reply to Piquereau and Perros and to Pullamsetti and de Jesus Perez.

Published in:

2019

By:

Kurakula, Kondababu;
Boucherat, Olivier;
Van der Feen, Diederik E.;
Jan Bogaard, Harm;
Kulikowski, Ewelina;
Bartelds, Beatrijs;
Provencher, Steeve;
Berger, Rolf M. F.;
Bonnet, Sébastien;
Goumans, Marie-José;
Bogaard, Harm Jan

Publication type:

Letter

BET Bromodomain Inhibitors and Pulmonary Arterial Hypertension: Take Care of the Heart.

Published in:

2019

By:

Piquereau, Jérôme;
Perros, Frédéric

Publication type:

Letter

Water molecules in protein-ligand interfaces. Evaluation of software tools and SAR comparison.

Published in:

Journal of Computer-Aided Molecular Design, 2019, v. 33, n. 3, p. 307, doi. 10.1007/s10822-019-00187-y

By:

Nittinger, Eva;
Gibbons, Paul;
Eigenbrot, Charles;
Davies, Doug R.;
Maurer, Brigitte;
Yu, Christine L.;
Kiefer, James R.;
Kuglstatter, Andreas;
Murray, Jeremy;
Ortwine, Daniel F.;
Tang, Yong;
Tsui, Vickie

Publication type:

Article

Anti-tumor activity of BET inhibitors in androgen-receptor-expressing triple-negative breast cancer.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-49366-9

By:

Park, In Hae;
Yang, Han Na;
Jeon, Su Yeon;
Hwang, Jung-Ah;
Kim, Min Kyeong;
Kong, Sun-Young;
Shim, Sung Hoon;
Lee, Keun Seok

Publication type:

Article

SMARCA2-deficiency confers sensitivity to targeted inhibition of SMARCA4 in esophageal squamous cell carcinoma cell lines.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-48152-x

By:

Ehrenhöfer-Wölfer, Katharina;
Puchner, Teresa;
Schwarz, Cornelia;
Rippka, Janine;
Blaha-Ostermann, Silvia;
Strobl, Ursula;
Hörmann, Alexandra;
Bader, Gerd;
Kornigg, Stefan;
Zahn, Stephan;
Sommergruber, Wolfgang;
Schweifer, Norbert;
Zichner, Thomas;
Schlattl, Andreas;
Neumüller, Ralph A.;
Shi, Junwei;
Vakoc, Christopher R.;
Kögl, Manfred;
Petronczki, Mark;
Kraut, Norbert

Publication type:

Article

Expression Characteristics and Clinical Correlations of BRD1 in Colorectal Cancer Samples.

Published in:

Technology in Cancer Research & Treatment, 2021, p. 1, doi. 10.1177/15330338211039678

By:

Li, Zhou;
Wang, Junjie;
Ji, Yuzhu;
Song, Fangzhou

Publication type:

Article

BET protein inhibitor apabetalone represses Porphyromonas gingivalis LPS-induced macrophage M1 polarization via regulating miR-130a/STAT3 axis.

Published in:

Biocell, 2022, v. 46, n. 10, p. 2281, doi. 10.32604/biocell.2022.020697

By:

MEIHUA CHEN;
HUIHUI WANG;
XIAOFENG CHEN;
YAN CHEN;
TIANYING BIAN

Publication type:

Article

Co-clinical Modeling of the Activity of the BET Inhibitor Mivebresib (ABBV-075) in AML.

Published in:

In Vivo, 2022, v. 36, n. 4, p. 1615, doi. 10.21873/invivo.12872

By:

ALBERT, DANIEL H.;
GOODWIN, NEAL C.;
DAVIES, ANGELA M.;
ROWE, JENNY;
FEUER, GEROLD;
BOYIADZIS, MICHAEL;
DORRITIE, KATHLEEN A.;
MANCINI, MARIA;
GANDOUR-EDWARDS, REGINA;
JONAS, BRIAN A.;
BORTHAKUR, GAUTAM;
ALDOSS, IBRAHIM;
RIZZIERI, DAVID A.;
ODENIKE, OLATOYOSI;
PREBET, THOMAS;
SINGH, SANJANA;
POPOVIC, RELJA;
SHEN, YU;
MCDANIEL, KEITH F.;
KATI, WARREN M.

Publication type:

Article

A biomimetic assay platform for the interrogation of antigen-dependent anti-tumor T-cell function.

Published in:

Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02569-1

By:

To, Jeremy;
Quackenbush, Doug;
Rowell, Emily;
Li, Lilin;
Reed, Connor;
Lo, Frederick;
Horman, Shane R.

Publication type:

Article

Is BRD7 associated with spermatogenesis impairment and male infertility in humans? A case-control study in a Han Chinese population.

Published in:

Basic & Clinical Andrology, 2021, v. 31, n. 1, p. 1, doi. 10.1186/s12610-021-00139-3

By:

He, Tianrong;
Liu, Mohan;
Tao, Dachang;
Leng, Xiangyou;
Wang, Zhaokun;
Xie, Shengyu;
Zhang, Yangwei;
Zhang, Xinyue;
Tan, Xiaolan;
Liu, Yunqiang;
Yang, Yuan

Publication type:

Article

Bromodomain protein Brd3 promotes Ifnb1 transcription via enhancing IRF3/p300 complex formation and recruitment to Ifnb1 promoter in macrophages.

Published in:

Scientific Reports, 2017, v. 7, n. 1, p. N.PAG, doi. 10.1038/srep39986

By:

Ren, Wenhui;
Wang, Chunmei;
Wang, Qinlan;
Zhao, Dezhi;
Zhao, Kai;
Sun, Donghao;
Liu, Xingguang;
Han, Chaofeng;
Hou, Jin;
Li, Xia;
Zhang, Qian;
Cao, Xuetao;
Li, Nan

Publication type:

Article

Bromodomain-containing protein BRPF1 is a therapeutic target for liver cancer.

Published in:

Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02405-6

By:

Cheng, Carol Lai-Hung;
Tsang, Felice Hoi-Ching;
Wei, Lai;
Chen, Mengnuo;
Chin, Don Wai-Ching;
Shen, Jialing;
Law, Cheuk-Ting;
Lee, Derek;
Wong, Carmen Chak-Lui;
Ng, Irene Oi-Lin;
Wong, Chun-Ming

Publication type:

Article

BETs that cover the spread from acquired to heritable heart failure.

Published in:

Journal of Clinical Investigation, 2020, v. 130, n. 9, p. 4536, doi. 10.1172/JCI140304

By:

Alexanian, Michael;
Haldar, Saptarsi M.

Publication type:

Article