Works matching DE "BROMODOMAIN-containing proteins"
Results: 242
Alkenyl oxindole is a novel PROTAC moiety that recruits the CRL4<sup>DCAF11</sup> E3 ubiquitin ligase complex for targeted protein degradation.
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- PLoS Biology, 2024, v. 22, n. 5, p. 1, doi. 10.1371/journal.pbio.3002550
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- Article
Identification of Novel Nuclear Protein Interactions with the N-Terminal Part of Filamin A.
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- Bioscience, Biotechnology & Biochemistry, 2011, v. 75, n. 1, p. 145, doi. 10.1271/bbb.100567
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- Article
Senolysis Enabled by Senescent Cell‐Sensitive Bioorthogonal Tetrazine Ligation.
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- Angewandte Chemie, 2024, v. 136, n. 9, p. 1, doi. 10.1002/ange.202315425
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- Article
An Activity‐Based Probe Targeting Non‐Catalytic, Highly Conserved Amino Acid Residues within Bromodomains.
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- Angewandte Chemie, 2019, v. 131, n. 4, p. 1019, doi. 10.1002/ange.201807825
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- Article
The Role of BPTF in Melanoma Progression and in Response to BRAF-Targeted Therapy.
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- JNCI: Journal of the National Cancer Institute, 2015, v. 107, n. 5, p. 1, doi. 10.1093/jnci/djv034
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- Article
Epigenetic Reader Bromodomain-Containing Protein 4 in Aging-Related Vascular Pathologies and Diseases: Molecular Basis, Functional Relevance, and Clinical Potential.
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- Biomolecules (2218-273X), 2023, v. 13, n. 7, p. 1135, doi. 10.3390/biom13071135
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- Article
Dopamine Transporter Knockout Rats Display Epigenetic Alterations in Response to Cocaine Exposure.
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- Biomolecules (2218-273X), 2023, v. 13, n. 7, p. 1107, doi. 10.3390/biom13071107
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- Article
TRIM28 promotes tumor growth and metastasis in breast cancer by targeting the BRD7 protein for ubiquitination and degradation.
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- Cellular Oncology (2211-3428), 2024, v. 47, n. 5, p. 1973, doi. 10.1007/s13402-024-00981-3
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- Article
When are the BET factors the most sensitive to bromodomain inhibitors?
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- Transcription (2154-1264), 2013, v. 4, n. 2, p. 1, doi. 10.4161/trns.23191
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- Article
Two faces of BRD4.
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- Transcription (2154-1264), 2013, v. 4, n. 1, p. 13, doi. 10.4161/trns.22542
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- Article
Control of NF- kB activity in human melanoma by bromodomain and extra-terminal protein inhibitor I- BET151.
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- Pigment Cell & Melanoma Research, 2014, v. 27, n. 6, p. 1126, doi. 10.1111/pcmr.12282
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- Article
BRD9 Inhibition Attenuates Matrix Degradation and Pyroptosis in Nucleus Pulposus by Modulating the NOX1/ROS/NF-κB axis.
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- Inflammation, 2023, v. 46, n. 3, p. 1002, doi. 10.1007/s10753-023-01786-6
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- Article
BRD4 sustains p63 transcriptional program in keratinocytes.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-024-00547-1
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- Article
Comparative Metabolism of Free-living Bodo saltans and Parasitic Trypanosomatids.
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- Journal of Eukaryotic Microbiology, 2016, v. 63, n. 5, p. 657, doi. 10.1111/jeu.12315
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- Article
Epigenetic Readers of Lysine Acetylation Regulate Cocaine-Induced Plasticity.
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- Journal of Neuroscience, 2015, v. 35, n. 45, p. 15062, doi. 10.1523/JNEUROSCI.0826-15.2015
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- Article
BRD4 and Cancer: going beyond transcriptional regulation.
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- Molecular Cancer, 2018, v. 17, n. 1, p. N.PAG, doi. 10.1186/s12943-018-0915-9
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- Article
TRIM24 links a non-canonical histone signature to breast cancer.
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- Nature, 2010, v. 468, n. 7326, p. 927, doi. 10.1038/nature09542
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- Article
Cooperative binding of two acetylation marks on a histone tail by a single bromodomain.
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- Nature, 2009, v. 461, n. 7264, p. 664, doi. 10.1038/nature08397
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- Article
Bromodomain‐containing protein 4 inhibition improves the efficacy of cisplatin and radiotherapy in oral squamous cell carcinoma by suppressing programmed cell death‐ligand 1 expression.
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- Basic & Clinical Pharmacology & Toxicology, 2024, v. 134, n. 2, p. 272, doi. 10.1111/bcpt.13962
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- Article
BET Family Protein BRD4: An Emerging Actor in NFκB Signaling in Inflammation and Cancer.
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- Biomedicines, 2018, v. 6, n. 1, p. 16, doi. 10.3390/biomedicines6010016
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- Article
BET protein inhibition mitigates acute myocardial infarction damage in rats via the TLR4/TRAF6/NF-κB pathway.
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- Experimental & Therapeutic Medicine, 2015, v. 10, n. 6, p. 2319, doi. 10.3892/etm.2015.2789
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- Article
Bromodomain and extra-terminal protein mimic JQ1 decreases inflammation in human vascular endothelial cells: Implications for pulmonary arterial hypertension.
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- Respirology, 2017, v. 22, n. 1, p. 157, doi. 10.1111/resp.12872
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- Article
The Role of Bromodomain Testis-Specific Factor, BRDT, in Cancer: A Biomarker and A Possible Therapeutic Target.
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- Cell Journal (Yakhteh), 2017, v. 19, p. 1, doi. 10.22074/cellj.2017.5060
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- Article
A convenient one-pot synthesis of novel heterocyclic systems of 9-chloro-4-methyl-6,11-dihydro-5H-benzo[b]pyrimido[4,5-e][1,4]diazepine and inhibitory evaluation against bromodomain-containing protein 4 (BRD4) enzyme by molecular docking.
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- Journal of the Iranian Chemical Society, 2023, v. 20, n. 11, p. 2841, doi. 10.1007/s13738-023-02880-0
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BET Inhibitor JQ1 Blocks Inflammation and Bone Destruction.
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- 2014
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- journal article
aBETting therapeutic resistance by Wnt signaling.
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- Cell Research, 2015, v. 25, n. 11, p. 1187, doi. 10.1038/cr.2015.127
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- Article
BETs abet Tam-R in ER-positive breast cancer.
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- Cell Research, 2014, v. 24, n. 8, p. 899, doi. 10.1038/cr.2014.90
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- Article
Structural insights into selective histone H3 recognition by the human Polybromo bromodomain 2.
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- Cell Research, 2010, v. 20, n. 5, p. 529, doi. 10.1038/cr.2010.43
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- Article
Papillomavirus-Associated Tumor Formation Critically Depends on c-Fos Expression Induced by Viral Protein E2 and Bromodomain Protein Brd4.
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- PLoS Pathogens, 2016, v. 12, n. 1, p. 1, doi. 10.1371/journal.ppat.1005366
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An In-Depth Comparison of Latency-Reversing Agent Combinations in Various In Vitro and Ex Vivo HIV-1 Latency Models Identified Bryostatin-1+JQ1 and Ingenol-B+JQ1 to Potently Reactivate Viral Gene Expression.
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- PLoS Pathogens, 2015, v. 11, n. 7, p. 1, doi. 10.1371/journal.ppat.1005063
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- Article
Papillomavirus Genomes Associate with BRD4 to Replicate at Fragile Sites in the Host Genome.
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- PLoS Pathogens, 2014, v. 10, n. 5, p. 1, doi. 10.1371/journal.ppat.1004117
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- Article
Bromodomain Protein Brd4 Plays a Key Role in Merkel Cell Polyomavirus DNA Replication.
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- PLoS Pathogens, 2012, v. 8, n. 11, p. 1, doi. 10.1371/journal.ppat.1003021
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- Article
The RNA-dependent association of phosphatidylinositol 4,5-bisphosphate with intrinsically disordered proteins contribute to nuclear compartmentalization.
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- PLoS Genetics, 2024, v. 20, n. 12, p. 1, doi. 10.1371/journal.pgen.1011462
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- Article
A Comparative Study of Fluorescence Assays in Screening for BRD4.
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- Assay & Drug Development Technologies, 2018, v. 16, n. 7, p. 372, doi. 10.1089/adt.2018.850
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Literature Search and Review.
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- Assay & Drug Development Technologies, 2017, v. 15, n. 5, p. 190, doi. 10.1089/adt.2017.29060.lit
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Characterisation of different types of dispersoids present in homogenised Al-4·5Zn-1Mg alloy containing Zr, Cr and Mn.
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- Materials Science & Technology, 2011, v. 27, n. 8, p. 1294, doi. 10.1179/026708310X12635619988267
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- Article
BET inhibitor resistance emerges from leukaemia stem cells.
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- Nature, 2015, v. 525, n. 7570, p. 538, doi. 10.1038/nature14888
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- Article
Transcriptional plasticity promotes primary and acquired resistance to BET inhibition.
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- Nature, 2015, v. 525, n. 7570, p. 543, doi. 10.1038/nature14898
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- Article
Therapeutic targeting of BET bromodomain proteins in castration-resistant prostate cancer.
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- Nature, 2014, v. 510, n. 7504, p. 278, doi. 10.1038/nature13229
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- Article
The bromodomain protein Brd4 insulates chromatin from DNA damage signalling.
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- Nature, 2013, v. 498, n. 7453, p. 246, doi. 10.1038/nature12147
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- Article
Reproductive biology: Molecule blocks sperm production.
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- Nature, 2012, v. 488, n. 7412, p. 432, doi. 10.1038/488432d
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- Article
Docking‑based virtual screening of BRD4 (BD1) inhibitors: assessment of docking methods, scoring functions and in silico molecular properties.
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- BMC Chemistry, 2024, v. 18, n. 1, p. 1, doi. 10.1186/s13065-024-01362-5
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- Article
Epigenetics: Targeting chromatin regulation in PDAC.
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- 2015
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- journal article
Anticancer drugs: Selectively targeting proteins for degradation.
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- Nature Reviews Drug Discovery, 2015, v. 14, n. 7, p. 459, doi. 10.1038/nrd4670
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- Article
Cancer: Epigenetic target in Hedgehog-driven tumours.
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- Nature Reviews Drug Discovery, 2014, v. 13, n. 9, p. 654, doi. 10.1038/nrd4428
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- Article
Cardiology: Bromodomain inhibition halts heart failure.
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- Nature Reviews Drug Discovery, 2013, v. 12, n. 10, p. 740, doi. 10.1038/nrd4134
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- Article
BRD9 is an essential regulator of glycolysis that creates an epigenetic vulnerability in colon adenocarcinoma.
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- Cancer Medicine, 2023, v. 12, n. 2, p. 1572, doi. 10.1002/cam4.4954
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- Article
The Microtubule-Targeting Agent Pretubulysin Impairs the Inflammatory Response in Endothelial Cells by a JNK-Dependent Deregulation of the Histone Acetyltransferase Brd4.
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- Cells (2073-4409), 2023, v. 12, n. 16, p. 2112, doi. 10.3390/cells12162112
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Genome-wide analysis of bromodomain gene family in Arabidopsis and rice.
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- Frontiers in Plant Science, 2023, v. 14, p. 1, doi. 10.3389/fpls.2023.1120012
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- Article
Menin as a hub controlling mixed lineage leukemia.
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- BioEssays, 2012, v. 34, n. 9, p. 771, doi. 10.1002/bies.201200007
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- Article