Works matching DE "BROMODOMAIN-containing proteins"
Results: 242
Targeting BRD4 ameliorates experimental emphysema by disrupting super-enhancer in polarized alveolar macrophage.
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- Respiratory Research, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s12931-025-03120-0
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- Article
Structure of the p300 catalytic core and implications for chromatin targeting and HAT regulation.
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- Nature Structural & Molecular Biology, 2013, v. 20, n. 9, p. 1040, doi. 10.1038/nsmb.2642
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- Article
Identification of Novel Nuclear Protein Interactions with the N-Terminal Part of Filamin A.
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- Bioscience, Biotechnology & Biochemistry, 2011, v. 75, n. 1, p. 145, doi. 10.1271/bbb.100567
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- Article
BRD4 inhibitors broadly promote erastin-induced ferroptosis in different cell lines by targeting ROS and FSP1.
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- Discover Oncology, 2024, v. 15, n. 1, p. 1, doi. 10.1007/s12672-024-00928-y
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- Article
Genome-wide analysis of bromodomain gene family in Arabidopsis and rice.
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- Frontiers in Plant Science, 2023, v. 14, p. 1, doi. 10.3389/fpls.2023.1120012
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- Article
Nanovesicles loaded with a TGF-β receptor 1 inhibitor overcome immune resistance to potentiate cancer immunotherapy.
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- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-39035-x
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- Article
Menin as a hub controlling mixed lineage leukemia.
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- BioEssays, 2012, v. 34, n. 9, p. 771, doi. 10.1002/bies.201200007
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- Article
A Review of the Bromodomain and Extraterminal Domain Epigenetic Reader Proteins: Function on Virus Infection and Cancer.
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- Viruses (1999-4915), 2024, v. 16, n. 7, p. 1096, doi. 10.3390/v16071096
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- Article
Control of NF- kB activity in human melanoma by bromodomain and extra-terminal protein inhibitor I- BET151.
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- Pigment Cell & Melanoma Research, 2014, v. 27, n. 6, p. 1126, doi. 10.1111/pcmr.12282
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- Article
A convenient one-pot synthesis of novel heterocyclic systems of 9-chloro-4-methyl-6,11-dihydro-5H-benzo[b]pyrimido[4,5-e][1,4]diazepine and inhibitory evaluation against bromodomain-containing protein 4 (BRD4) enzyme by molecular docking.
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- Journal of the Iranian Chemical Society, 2023, v. 20, n. 11, p. 2841, doi. 10.1007/s13738-023-02880-0
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- Article
The Generation of a Library of Bromodomain-Containing Protein Modulators Expedited by Continuous Flow Synthesis.
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- European Journal of Organic Chemistry, 2016, v. 2016, n. 11, p. 2000, doi. 10.1002/ejoc.201600222
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- Article
Discovery of a PCAF Bromodomain Chemical Probe.
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- Angewandte Chemie International Edition, 2017, v. 56, n. 3, p. 827, doi. 10.1002/anie.201610816
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- Article
A Chemical Probe for the ATAD2 Bromodomain.
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- Angewandte Chemie International Edition, 2016, v. 55, n. 38, p. 11382, doi. 10.1002/anie.201603928
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- Article
Isoxazole-Derived Amino Acids are Bromodomain-Binding Acetyl-Lysine Mimics: Incorporation into Histone H4 Peptides and Histone H3.
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- Angewandte Chemie International Edition, 2016, v. 55, n. 29, p. 8353, doi. 10.1002/anie.201602908
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- Publication type:
- Article
Redesign of a Fluorogenic Labeling System To Improve Surface Charge, Brightness, and Binding Kinetics for Imaging the Functional Localization of Bromodomains.
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- Angewandte Chemie International Edition, 2015, v. 54, n. 48, p. 14368, doi. 10.1002/anie.201506935
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- Article
LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor.
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- Angewandte Chemie International Edition, 2015, v. 54, n. 21, p. 6217, doi. 10.1002/anie.201501394
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- Publication type:
- Article
Keap1-Independent Regulation of Nrf2 Activity by Protein Acetylation and a BET Bromodomain Protein.
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- PLoS Genetics, 2016, v. 12, n. 5, p. 1, doi. 10.1371/journal.pgen.1006072
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- Article
Stress-Induced Nuclear RNA Degradation Pathways Regulate Yeast Bromodomain Factor 2 to Promote Cell Survival.
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- PLoS Genetics, 2014, v. 10, n. 9, p. 1, doi. 10.1371/journal.pgen.1004661
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- Article
Bromodomain and extra-terminal protein mimic JQ1 decreases inflammation in human vascular endothelial cells: Implications for pulmonary arterial hypertension.
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- Respirology, 2017, v. 22, n. 1, p. 157, doi. 10.1111/resp.12872
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- Article
The Microtubule-Targeting Agent Pretubulysin Impairs the Inflammatory Response in Endothelial Cells by a JNK-Dependent Deregulation of the Histone Acetyltransferase Brd4.
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- Cells (2073-4409), 2023, v. 12, n. 16, p. 2112, doi. 10.3390/cells12162112
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- Article
Brd4 maintains constitutively active NF-κB in cancer cells by binding to acetylated RelA.
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- Oncogene, 2014, v. 33, n. 18, p. 2395, doi. 10.1038/onc.2013.179
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- Article
Novel BRD4-NUT fusion isoforms increase the pathogenic complexity in NUT midline carcinoma.
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- Oncogene, 2013, v. 32, n. 39, p. 4664, doi. 10.1038/onc.2012.487
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- Article
Identification of bromodomain-containing protein-4 as a novel marker and epigenetic target in mast cell leukemia.
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- 2015
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- Publication type:
- journal article
Synergistic antitumor activity of lenalidomide with the BET bromodomain inhibitor CPI203 in bortezomib-resistant mantle cell lymphoma.
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- Leukemia (08876924), 2014, v. 28, n. 10, p. 2049, doi. 10.1038/leu.2014.106
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- Article
Recurrent mutations, including NPM1c, activate a BRD4-dependent core transcriptional program in acute myeloid leukemia.
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- Leukemia (08876924), 2014, v. 28, n. 2, p. 311, doi. 10.1038/leu.2013.338
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- Article
Inhibition of BET bromodomain improves anemia in APCmin mice.
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- Leukemia & Lymphoma, 2017, v. 58, n. 4, p. 989, doi. 10.1080/10428194.2016.1219907
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- Article
When are the BET factors the most sensitive to bromodomain inhibitors?
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- Transcription (2154-1264), 2013, v. 4, n. 2, p. 1, doi. 10.4161/trns.23191
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- Article
Two faces of BRD4.
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- Transcription (2154-1264), 2013, v. 4, n. 1, p. 13, doi. 10.4161/trns.22542
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- Article
Fucoxanthin inhibits cardiac fibroblast transdifferentiation by alleviating oxidative stress through downregulation of BRD4.
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- PLoS ONE, 2023, v. 18, n. 9, p. 1, doi. 10.1371/journal.pone.0291469
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- Article
Regulation of inflammatory genes in decidual cells: Involvement of the bromodomain and extra-terminal family proteins.
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- PLoS ONE, 2023, v. 17, n. 3, p. 1, doi. 10.1371/journal.pone.0280645
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- Article
Emerging roles of bromodomain protein 4 in regulation of stem cell identity.
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- Stem Cells, 2021, v. 39, n. 12, p. 1615, doi. 10.1002/stem.3454
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- Article
Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma.
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- Nature Medicine, 2015, v. 21, n. 10, p. 1163, doi. 10.1038/nm.3952
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- Article
Ruxolitinib after fedratinib failure in patients with myelofibrosis: A real‐world case series.
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- British Journal of Haematology, 2024, v. 205, n. 4, p. 1605, doi. 10.1111/bjh.19654
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- Article
Preclinical evaluation of the BET bromodomain inhibitor BAY 1238097 for the treatment of lymphoma.
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- British Journal of Haematology, 2017, v. 178, n. 6, p. 936, doi. 10.1111/bjh.14803
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- Article
Synergistic induction of cell death in haematological malignancies by combined phosphoinositide-3-kinase and BET bromodomain inhibition.
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- British Journal of Haematology, 2015, v. 170, n. 2, p. 275, doi. 10.1111/bjh.13283
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- Article
Bromodomain Inhibition Reveals FGF15/19 As a Target of Epigenetic Regulation and Metabolic Control.
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- 2022
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- Publication type:
- journal article
Essential gene screening identifies the bromodomain-containing protein BRPF1 as a new actionable target for endocrine therapy-resistant breast cancers.
- Published in:
- Molecular Cancer, 2024, v. 23, n. 1, p. 1, doi. 10.1186/s12943-024-02071-2
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- Article
BRD4 and Cancer: going beyond transcriptional regulation.
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- Molecular Cancer, 2018, v. 17, n. 1, p. N.PAG, doi. 10.1186/s12943-018-0915-9
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- Article
Reiterative Enrichment and Authentication of CRISPRi Targets (REACT) identifies the proteasome as a key contributor to HIV-1 latency.
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- PLoS Pathogens, 2019, v. 15, n. 1, p. 1, doi. 10.1371/journal.ppat.1007498
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- Article
Chromatin remodeling controls Kaposi's sarcoma-associated herpesvirus reactivation from latency.
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- PLoS Pathogens, 2018, v. 14, n. 9, p. 1, doi. 10.1371/journal.ppat.1007267
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- Publication type:
- Article
Identification of BRD7 by whole-exome sequencing as a predictor for intermediate-stage hepatocellular carcinoma in patients undergoing TACE.
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- Journal of Cancer Research & Clinical Oncology, 2023, v. 149, n. 13, p. 11247, doi. 10.1007/s00432-023-04883-z
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- Publication type:
- Article
The prognostic significance of bromodomain PHD-finger transcription factor in colorectal carcinoma and association with vimentin and E-cadherin.
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- Journal of Cancer Research & Clinical Oncology, 2015, v. 141, n. 8, p. 1465, doi. 10.1007/s00432-015-1937-y
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- Publication type:
- Article
Epigenetics: Targeting chromatin regulation in PDAC.
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- 2015
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- Publication type:
- journal article
Anticancer drugs: Selectively targeting proteins for degradation.
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- Nature Reviews Drug Discovery, 2015, v. 14, n. 7, p. 459, doi. 10.1038/nrd4670
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- Publication type:
- Article
The Role of BPTF in Melanoma Progression and in Response to BRAF-Targeted Therapy.
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- JNCI: Journal of the National Cancer Institute, 2015, v. 107, n. 5, p. 1, doi. 10.1093/jnci/djv034
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- Article
Two structurally distinct domains of the nucleoporin Nup170 cooperate to tether a subset of nucleoporins to nuclear pores.
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- Journal of Cell Biology, 2009, v. 185, n. 3, p. 387, doi. 10.1083/jcb.200810016
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- Publication type:
- Article
The Cellular Bromodomain Protein Brd4 has Multiple Functions in E2-Mediated Papillomavirus Transcription Activation.
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- Viruses (1999-4915), 2014, v. 6, n. 8, p. 3228, doi. 10.3390/v6083228
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- Publication type:
- Article
Bromodomain Proteins in HIV Infection.
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- Viruses (1999-4915), 2013, v. 5, n. 6, p. 1571, doi. 10.3390/v5061571
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- Publication type:
- Article
Research Progress on Pathogenesis and Treatment of NUT Carcinoma.
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- Chinese Journal of Lung Cancer, 2024, v. 27, n. 6, p. 466, doi. 10.3779/j.issn.1009-3419.2024.101.16
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- Article
LncRNA AL139294.1 can be transported by extracellular vesicles to promote the oncogenic behaviour of recipient cells through activation of the Wnt and NF-κB2 pathways in non-small-cell lung cancer.
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- Journal of Experimental & Clinical Cancer Research (17569966), 2024, v. 43, n. 1, p. 1, doi. 10.1186/s13046-023-02939-z
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- Article