Works matching DE "BISPECIFIC antibodies"

Results: 1391

Resistance Mechanisms to BCMA Targeting Bispecific Antibodies and CAR T-Cell Therapies in Multiple Myeloma.

Published in:

Cells (2073-4409), 2025, v. 14, n. 14, p. 1077, doi. 10.3390/cells14141077

By:

Tedder, Brandon;
Bhutani, Manisha

Publication type:

Article

Multi-courses of blinatumomab combined with reduced dose chemotherapy has been successfully used in chemo-intolerant middle to high-risk pediatric B-ALL patients with invasive fungal disease.

Published in:

Annals of Hematology, 2025, v. 104, n. 6, p. 3495, doi. 10.1007/s00277-025-06432-9

By:

Zhou, En-Min;
Tang, Yongmin;
Liao, Chan;
Lin, Shupeng;
Shen, Heping;
Wang, Di;
Xu, Liyao;
Zhang, Ping;
Song, Hua;
Xu, Xiaojun;
Zhang, Jingying;
Liang, Juan;
Shen, Diying;
Zhao, Fenying;
Xu, Weiqun

Publication type:

Article

Editorial: Advancements in drug development: exploring bi-specific antibodies as promising therapeutic strategies in oncology.

Published in:

2025

By:

Weber, Urs M.;
Bailis, Julie M.;
Coxon, Angela;
Pine, Sharon R.;
Giaccone, Giuseppe

Publication type:

Editorial

Tyrosine kinase inhibitors with blinatumomab versus chemotherapy in Philadelphia‐positive acute B‐lymphoblastic leukemia.

Published in:

International Journal of Cancer, 2025, v. 157, n. 6, p. 1197, doi. 10.1002/ijc.35468

By:

Stolz, Sebastian M.;
Hofer, Kevin D.;
Rösler, Wiebke;
Deuel, Jeremy;
Schwotzer, Rahel;
Schneidawind, Corina;
Schneidawind, Dominik;
Manz, Markus G.;
Rieger, Max J.

Publication type:

Article

Are transplant strategies in relapsed myeloma relevant in the cellular treatment era?

Published in:

Cancer (0008543X), 2025, v. 131, n. 14, p. 1, doi. 10.1002/cncr.70005

By:

Fotiou, Despina;
Kastritis, Efstathios

Publication type:

Article

Talquetamab improves patient‐reported symptoms and health‐related quality of life in relapsed or refractory multiple myeloma: Results from the phase 1/2 MonumenTAL‐1 study.

Published in:

Cancer (0008543X), 2025, v. 131, n. 14, p. 1, doi. 10.1002/cncr.35927

By:

Schinke, Carolina;
Touzeau, Cyrille;
Oriol, Albert;
Mateos, María‐Victoria;
Stevens, Don;
Rasche, Leo;
Qin, Xiang;
Kato, Kelly;
Bathija, Sacheeta;
Katz, Eva G.;
Gries, Katharine S.;
Campagna, Michela;
Masterson, Tara;
Hilder, Brandi W.;
Tolbert, Jaszianne;
Renaud, Thomas;
Heuck, Christoph;
Tomlinson, Chalmer;
Moreau, Philippe;
San‐Miguel, Jesús

Publication type:

Article

Dose Selection for DuoBody®‐CD40x4‐1BB (GEN1042/BNT312) Using a mPBPK/RO Model Leveraging Preclinical and Clinical Data.

Published in:

Clinical Pharmacology & Therapeutics, 2025, v. 118, n. 2, p. 418, doi. 10.1002/cpt.3677

By:

Bajaj, Gaurav;
Shchelokov, Dmitry;
Demin, Oleg;
Adams, Homer C.;
Feng, Yan;
Gibiansky, Leonid;
van der Lee, Saskia;
Johri, Anandhi;
Belete, Merzu;
Muik, Alexander;
Panorchan, Porntula;
Türeci, Özlem;
Sahin, Uğur;
Ahmadi, Tahamtan;
Gupta, Manish;
Thalhauser, Craig

Publication type:

Article

Short-term real-world effectiveness of faricimab on macular edema due to retinal vein occlusion.

Published in:

International Journal of Retina & Vitreous, 2025, v. 11, n. 1, p. 1, doi. 10.1186/s40942-025-00703-3

By:

Hirakata, Toshiaki;
Toride, Ai;
Ashikaga, Kenta;
Nakagawa, Takanori;
Hara, Fumihiro;
Nochi, Yuta;
Yamamoto, Shutaro;
Hiratsuka, Yoshimune;
Nakao, Shintaro

Publication type:

Article

Efficacy and safety of cadonilimab (PD-1/CTLA-4 bi-specific antibody) and adjuvant anti-angiogenesis therapy in treated, recurrent, or metastatic cervical cancer.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1614434

By:

Zhou, Fang;
Liu, Shushu;
Zuo, Ying;
Naseem, Danial F.;
Li, Yinguang;
Wang, Yin;
Meng, Cuicui;
Song, Yipeng

Publication type:

Article

Teclistamab-associated cytokine release syndrome in multiple myeloma: a case-based literature review of mechanisms, management, and clinical implications.

Published in:

2025

By:

Cheema, Muhammad;
Syed, Salman;
Ghuman, Zoha;
Iftikhar, Asma

Publication type:

Case Study

Recent Advances in Antibody Therapy for Alzheimer's Disease: Focus on Bispecific Antibodies.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6271, doi. 10.3390/ijms26136271

By:

Yang, Han-Mo

Publication type:

Article

Enterocolitis associated with glofitamab—First report and clinicopathological findings in three cases.

Published in:

British Journal of Haematology, 2025, v. 206, n. 6, p. 1654, doi. 10.1111/bjh.20052

By:

McKeague, Sean;
Robertson, Molly;
van der Linde, Sam;
Khoo, Christine;
Segal, Jonathan;
Harrop, Sean;
Minson, Adrian;
Roberts, Andrew W.;
Dickinson, Michael

Publication type:

Article

Revolutions at the frontline of multiple myeloma treatment: lessons and challenges to finding a cure.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1578529

By:

Kort, Jeries;
Rivera, Andrea;
Senigarapu, Sindhuja;
Driscoll, James J.

Publication type:

Article

Antibody treatment of hepatocellular carcinoma: a review of current and emerging approaches.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1533874

By:

El-Kafrawy, Sherif A.;
Elkafrawy, Mostafa S.;
Azhar, Esam I.;
Saeed, Anwaar;
Tabll, Ashraf A.

Publication type:

Article

Designs of NKG2D-based immunotherapeutics for cancer.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1557644

By:

Han, Jianfeng;
Wang, Youwei;
Chan, Godfrey Chi-Fung;
Chan, Wing Keung

Publication type:

Article

Double hit -- bispecific antibodies in cancer therapy.

Published in:

Oncology in Clinical Practice (2450-1654), 2025, v. 21, n. 3, p. 222, doi. 10.5603/ocp.98901

By:

Bogdanowicz, Alicja;
Wojas-Krawczyk, Kamila;
Krzyżanowska, Natalia;
Krawczyk, Paweł

Publication type:

Article

Single-domain antibodies directed against hemagglutinin and neuraminidase protect against influenza B viruses.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60232-3

By:

Matthys, Arne;
Felix, Jan;
Catani, Joao Paulo Portela;
Roose, Kenny;
Nerinckx, Wim;
Van Buyten, Benthe;
Fijalkowska, Daria;
Callewaert, Nico;
Savvides, Savvas N.;
Saelens, Xavier

Publication type:

Article

Characterization and functional evaluation of JS207, a novel bispecific antibody against human PD-1 and VEGFA.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1612547

By:

Lin, Shihua;
Hong, Min;
Zhang, Jing;
Zhao, Wenting;
Li, Ke;
Wu, Chun;
Yang, Qiuyun;
Xiao, Yi;
Huang, Lanqing;
Wang, Jing;
Jia, Aijuan;
Wang, Xujia;
Yao, Sheng

Publication type:

Article

Emerging therapeutic agents in multiple myeloma: highlights from the 2024 ASH annual meeting.

Published in:

2025

By:

Zhang, Qing;
Song, Yongping;
Zhou, Keshu;
Lin, Quande

Publication type:

Letter

A Cost-Effectiveness Analysis of Diffuse Large B-Cell Lymphoma Treatment Pathways in the United States.

Published in:

MDM Policy & Practice, 2025, v. 10, n. 1, p. 1, doi. 10.1177/23814683251345780

By:

Patel, Anik R.;
Kievit, Bradley;
Hasegawa, Ken;
Ray, Markqayne;
Sharma, Rishika;
Hofmann, Sarahmaria;
Blissett, Rob;
Locke, Frederick L.

Publication type:

Article

多发性骨髓瘤的免疫治疗: 成果与挑战.

Published in:

Chinese Journal of Biochemistry & Molecular Biology, 2025, v. 41, n. 6, p. 774, doi. 10.13865/j.cnki.cjbmb.2025.05.1510

By:

王菲;
孙春艳

Publication type:

Article

An Updated Indirect Comparison of Elranatamab Versus a Real-World External Control Arm in Triple-Class Refractory Multiple Myeloma.

Published in:

Blood & Lymphatic Cancer: Targets & Therapy, 2025, v. 14, p. 11, doi. 10.2147/BLCTT.S516356

By:

Costa, Luciano J;
LeBlanc, Thomas W;
Tesch, Hans;
Sonneveld, Pieter;
Johnson, Sarasa MA;
Vekeman, Francis;
Hlavacek, Patrick;
Meche, Aster;
Kim, Chai Hyun;
Cislo, Paul;
Hughes, David M;
Nador, Guido;
DiBonaventura, Marco

Publication type:

Article

Discovery of Synergistic Broadly Neutralizing Antibodies Targeting Non-Dominant Epitopes on SARS-CoV-2 RBD and NTD.

Published in:

Vaccines, 2025, v. 13, n. 6, p. 592, doi. 10.3390/vaccines13060592

By:

Feng, Hualong;
Wang, Zuowei;
Li, Ling;
Li, Yunjian;
Lu, Maosheng;
Chen, Xixian;
Hu, Lin;
Sun, Yi;
Du, Ruiping;
Qin, Rongrong;
Chen, Xuanyi;
Jiang, Liwei;
Zuo, Teng

Publication type:

Article

Bispecific Antibodies in Solid Tumors: Advances and Challenges.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5838, doi. 10.3390/ijms26125838

By:

Shan, Khine Swe;
Musleh Ud Din, Saba;
Dalal, Shivani;
Gonzalez, Teresita;
Dalal, Misha;
Ferraro, Pablo;
Hussein, Atif;
Vulfovich, Michel

Publication type:

Article

Emerging Concepts of Targeted Protein Degrader Technologies via Lysosomal Pathways.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5582, doi. 10.3390/ijms26125582

By:

Alam, Mohammad Maqusood;
Wasim, Sobia;
Lee, Sang-Yoon

Publication type:

Article

The Evolving Landscape of Viral Infections in Immunocompromised Hosts.

Published in:

Viruses (1999-4915), 2025, v. 17, n. 6, p. 787, doi. 10.3390/v17060787

By:

Tayyar, Ralph;
Ho, Dora Y.

Publication type:

Article

Modeling of bispecific antibody elution in mixed-mode cation-exchange chromatography.

Published in:

Journal of Separation Science, 2017, v. 40, n. 18, p. 3632, doi. 10.1002/jssc.201700313

By:

Lee, Yi Feng;
Kluters, Simon;
Hillmann, Mirjam;
Hirschheydt, Thomas;
Frech, Christian

Publication type:

Article

A novel bispecific ligand-directed toxin designed to simultaneously target EGFR on human glioblastoma cells and uPAR on tumor neovasculature.

Published in:

Journal of Neuro-Oncology, 2011, v. 103, n. 2, p. 255, doi. 10.1007/s11060-010-0392-5

By:

Tsai, Alexander;
Oh, Seunguk;
Chen, Hua;
Shu, Yanqun;
Ohlfest, John;
Vallera, Daniel

Publication type:

Article

Production of a bispecific antibody targeting TNF-α and C5a in Pichia pastoris and its therapeutic potential in rheumatoid arthritis.

Published in:

Biotechnology Letters, 2020, v. 42, n. 4, p. 557, doi. 10.1007/s10529-020-02830-3

By:

Chen, Jin;
He, Zhonghui;
Fan, Yuran;
Zhou, Xiaodong;
Li, Lujun;
Liu, Mengyuan

Publication type:

Article

Visualization of the frequency effect of pulsed electric field on enzymatic browning of peel ground tissue.

Published in:

Food & Bioproducts Processing: Transactions of the Institution of Chemical Engineers Part C, 2023, v. 142, p. 82, doi. 10.1016/j.fbp.2023.09.003

By:

Ayu, Manazza;
Fincan, Mustafa

Publication type:

Article

Identification of Escherichia coli host cell for high plasmid stability and improved production of antihuman ovarian carcinoma × antihuman CD3 single-chain bispecific antibody.

Published in:

Applied Microbiology & Biotechnology, 2007, v. 76, n. 4, p. 795, doi. 10.1007/s00253-007-1050-5

By:

Zhao, Jing-Bo;
Wei, Dong-Zhi;
Tong, Wang-Yu

Publication type:

Article

Beyond BCL2 (B cell lymphoma) and BTK (Bruton tyrosine kinase) inhibitors: novel agents and resistance mechanisms for chronic lymphocytic leukemia.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02947-9

By:

Hays, Priya

Publication type:

Article

Adenine Quadruplexes Show Surprising Stability: Potential Implications for SARS-CoV-2.

Published in:

Journal of Computational Biophysics & Chemistry, 2021, v. 20, n. 7, p. 675, doi. 10.1142/S273741652150040X

By:

Chapman, Simon;
Ghesquière, Pierre;
Perry, Elliot;
Taylor, Peter Geoffrey;
Power, Nicholas P.;
Sansom, Clare E.;
Xu, Yao-Zhong

Publication type:

Article

A microfluidic bone marrow chip for the safety profiling of biologics in pre-clinical drug development.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-08137-1

By:

Koenig, Leopold;
Juglair, Laurent;
Tao, Thi Phuong;
Fischer, Susanne;
Clausen, Inga;
Imhof-Jung, Sabine;
Janssen, Niels;
Mader, Robert;
Marbach, Daniel;
Niewoehner, Jens;
Winter, Annika;
Schubert, Desirée

Publication type:

Article

Targeted immunotherapy: harnessing the immune system to battle multiple myeloma.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-01818-6

By:

Xu, Limei;
Wen, Caining;
Xia, Jiang;
Zhang, Hao;
Liang, Yujie;
Xu, Xiao

Publication type:

Article

Hematopoietic Stem Cell Transplantation: Recent Advances.

Published in:

Journal of Clinical Medicine, 2025, v. 14, n. 10, p. 3379, doi. 10.3390/jcm14103379

By:

Milone, Giuseppe;
Leotta, Salvatore;
Cupri, Alessandra

Publication type:

Article

Switching to Faricimab in Therapy-Resistant Macular Edema Due to Retinal Vein Occlusion: Initial Real-World Efficacy Outcomes.

Published in:

Journal of Clinical Medicine, 2025, v. 14, n. 7, p. 2454, doi. 10.3390/jcm14072454

By:

Hafner, Michael;
Herold, Tina R.;
Kufner, Alexander;
Asani, Ben;
Anschütz, Andreas;
Eckardt, Franziska;
Priglinger, Siegfried G.;
Schiefelbein, Johannes

Publication type:

Article

Advances in Biologic Therapies for Allergic Diseases: Current Trends, Emerging Agents, and Future Perspectives.

Published in:

Journal of Clinical Medicine, 2025, v. 14, n. 4, p. 1079, doi. 10.3390/jcm14041079

By:

Alska, Ewa;
Łaszczych, Dariusz;
Napiórkowska-Baran, Katarzyna;
Szymczak, Bartłomiej;
Rajewska, Alicja;
Rubisz, Aleksandra Ewa;
Romaniuk, Paulina;
Wrzesień, Katarzyna;
Mućka, Natalia;
Bartuzi, Zbigniew

Publication type:

Article

Characteristics of Microaneurysm Size in Residual Edema After Intravitreal Injection of Faricimab for Diabetic Macular Edema.

Published in:

Journal of Clinical Medicine, 2024, v. 13, n. 24, p. 7839, doi. 10.3390/jcm13247839

By:

Yamada, Yutaka;
Takamura, Yoshihiro;
Morioka, Masakazu;
Oshima, Hideyuki;
Gozawa, Makoto;
Matsumura, Takehiro;
Inatani, Masaru

Publication type:

Article

Emergencies in Hematology: Why, When and How I Treat?

Published in:

Journal of Clinical Medicine, 2024, v. 13, n. 24, p. 7572, doi. 10.3390/jcm13247572

By:

Duminuco, Andrea;
Del Fabro, Vittorio;
De Luca, Paola;
Leotta, Dario;
Limoli, Miriana Carmela;
Longo, Ermelinda;
Nardo, Antonella;
Santuccio, Gabriella;
Petronaci, Alessandro;
Stanzione, Gaia;
Di Raimondo, Francesco;
Palumbo, Giuseppe Alberto

Publication type:

Article

Target Therapy in Chronic Arthritis: The Unmet Needs, State-of-the-Art on Dual Biologic Treatments, and Future Perspectives.

Published in:

Journal of Clinical Medicine, 2024, v. 13, n. 23, p. 7303, doi. 10.3390/jcm13237303

By:

Rotondo, Cinzia;
Perniola, Simone;
Parisi, Simone;
Cantatore, Francesco Paolo;
Corrado, Addolorata

Publication type:

Article

Strengths and Weaknesses of Different Therapeutic Strategies for the Treatment of Patients with Multiple Myeloma Who Progress After the Frontline Use of Lenalidomide: A Narrative Review.

Published in:

Journal of Clinical Medicine, 2024, v. 13, n. 20, p. 6238, doi. 10.3390/jcm13206238

By:

Mele, Giuseppe;
Sgherza, Nicola;
Pastore, Domenico;
Musto, Pellegrino

Publication type:

Article

High-Risk Neuroblastoma Challenges and Opportunities for Antibody-Based Cellular Immunotherapy.

Published in:

Journal of Clinical Medicine, 2024, v. 13, n. 16, p. 4765, doi. 10.3390/jcm13164765

By:

Persaud, Natasha V.;
Park, Jeong A.;
Cheung, Nai Kong V.

Publication type:

Article

Beyond VEGF: Angiopoietin–Tie Signaling Pathway in Diabetic Retinopathy.

Published in:

Journal of Clinical Medicine, 2024, v. 13, n. 10, p. 2778, doi. 10.3390/jcm13102778

By:

Chen-Li, Genesis;
Martinez-Archer, Rebeca;
Coghi, Andres;
Roca, José A.;
Rodriguez, Francisco J.;
Acaba-Berrocal, Luis;
Berrocal, María H.;
Wu, Lihteh

Publication type:

Article

New Insights into First-Line Therapy in Diffuse Large B-Cell Lymphoma: Are We Improving Outcomes?

Published in:

Journal of Clinical Medicine, 2024, v. 13, n. 7, p. 1929, doi. 10.3390/jcm13071929

By:

Abrisqueta, Pau

Publication type:

Article

Primary Cutaneous CD30-Positive Lymphoproliferative Disorders—Current Therapeutic Approaches with a Focus on Brentuximab Vedotin.

Published in:

Journal of Clinical Medicine, 2024, v. 13, n. 3, p. 823, doi. 10.3390/jcm13030823

By:

Stein, Tomasz;
Robak, Tadeusz;
Biernat, Wojciech;
Robak, Ewa

Publication type:

Article

Management of Adverse Reactions for BCMA-Directed Therapy in Relapsed Multiple Myeloma: A Focused Review.

Published in:

Journal of Clinical Medicine, 2023, v. 12, n. 17, p. 5539, doi. 10.3390/jcm12175539

By:

Khanam, Razwana;
Faiman, Beth;
Batool, Saba;
Najmuddin, Mohammed Musa;
Usman, Rana;
Kuriakose, Kiran;
Ahmed, Arooj;
Rehman, Mohammad Ebad Ur;
Roksana, Zinath;
Syed, Zain;
Anwer, Faiz;
Raza, Shahzad

Publication type:

Article

Safe and Successful Surgical Outcome in Persons with Hemophilia A with and without Inhibitors Treated with Emicizumab: A Large, Single Center, Real-World Experience.

Published in:

Journal of Clinical Medicine, 2023, v. 12, n. 6, p. 2317, doi. 10.3390/jcm12062317

By:

Castaman, Giancarlo;
Linari, Silvia;
Pieri, Lisa;
Carulli, Christian;
Prosperi, Paolo;
Tonelli, Paolo;
Demartis, Francesco;
Fjerza, Rajmonda;
Attanasio, Monica;
Coppo, Mirella;
Salvianti, Francesca

Publication type:

Article

Current State of the Art and Prospects of T Cell-Redirecting Bispecific Antibodies in Multiple Myeloma.

Published in:

Journal of Clinical Medicine, 2021, v. 10, n. 19, p. 4593, doi. 10.3390/jcm10194593

By:

Hosny, Mashhour;
Verkleij, Christie P. M.;
van der Schans, Jort;
Frerichs, Kristine A.;
Mutis, Tuna;
Zweegman, Sonja;
van de Donk, Niels W. C. J.

Publication type:

Article

Bone Marrow Microenvironment Interplay and Current Clinical Practice in Multiple Myeloma: A Review of the Balkan Myeloma Study Group.

Published in:

Journal of Clinical Medicine, 2021, v. 10, n. 17, p. 3940, doi. 10.3390/jcm10173940

By:

Bila, Jelena;
Katodritou, Eirini;
Guenova, Margarita;
Basic-Kinda, Sandra;
Coriu, Daniel;
Dapcevic, Milena;
Ibricevic-Balic, Lejla;
Ivanaj, Arben;
Karanfilski, Oliver;
Zver, Samo;
Beksac, Meral;
Terpos, Evangelos;
Dimopoulos, Meletios Athanassios

Publication type:

Article