Works matching DE "BISPECIFIC antibodies"

Results: 1297

CAR-T-Zellen: Vielversprechende Therapieoption für B-Zell-Malignome.

Published in:

Trillium-Diagnostik, 2024, v. 22, n. 4, p. 292, doi. 10.47184/td.2024.04.08

By:

Friedrich, Maik;
Sack, Ulrich

Publication type:

Article

Comparative efficacy and safety of Faricimab with other intravitreal anti-vascular endothelial growth factor in the treatment of neovascular age--related macular degeneration - A systematic review and meta-analysis.

Published in:

Asian Journal of Medical Sciences, 2025, v. 16, n. 5, p. 136, doi. 10.71152/ajms.v16i5.4487

By:

Kaliaperumal, Renuga Devi;
P., Nandhini;
Mohan, Reena;
P., Nallamuthu

Publication type:

Article

Vitritis following intravitreal faricimab: a retrospective monocentric analysis.

Published in:

Graefe's Archive of Clinical & Experimental Ophthalmology, 2025, v. 263, n. 4, p. 965, doi. 10.1007/s00417-025-06736-6

By:

Bourdin, Alexandre;
Cohen, Salomon Yves;
Nghiem-Buffet, Sylvia;
Smadja, Jerome;
Paques, Michel;
Fajnkuchen, Franck;
Mrejen, Sarah

Publication type:

Article

A Reflection on the Evolution of Antibody‐Based Therapies in Oncology: Trastuzumab as an Exemplar—Commentary on Dijkers et al.

Published in:

Clinical Pharmacology & Therapeutics, 2025, v. 117, n. 6, p. 1577, doi. 10.1002/cpt.3651

By:

Holstein, Sarah A.

Publication type:

Article

A Novel Two‐Part Mixture Model for the Incidence and Time Course of Cytokine Release Syndrome After Elranatamab Dosing in Multiple Myeloma Patients.

Published in:

Clinical Pharmacology & Therapeutics, 2025, v. 117, n. 6, p. 1687, doi. 10.1002/cpt.3533

By:

Irby, Donald;
Hibma, Jennifer;
Elmeliegy, Mohamed;
Wang, Diane;
Vandendries, Erik;
Poels, Kamrine;
Shtylla, Blerta;
Williams, Jason H.

Publication type:

Article

A broad antibody with enhanced HIV-1 neutralization via bispecific antibody-mediated prepositioning.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60035-6

By:

Kim, Soohyun;
Radford, Caelan E.;
Xu, Duo;
Zhong, Jianing;
Do, Jonathan;
Pham, Dominic M.;
Travisano, Katie A.;
Filsinger Interrante, Maria V.;
Bruun, Theodora U. J.;
Rezek, Valerie;
Wilder, Bailey;
Palomares, Martina;
Seaman, Michael S.;
Kitchen, Scott G.;
Bloom, Jesse D.;
Kim, Peter S.

Publication type:

Article

Design of a prodrug bispecific antibody masked by a functional molecule for lymphocyte activation for cancer therapy.

Published in:

Journal of Biological Engineering, 2025, v. 19, n. 1, p. 1, doi. 10.1186/s13036-025-00517-9

By:

Miura, Daimei;
Kato, Yuki;
Yasunaga, Masahiro;
Kumagai, Izumi;
Asano, Ryutaro

Publication type:

Article

A microfluidic bone marrow chip for the safety profiling of biologics in pre-clinical drug development.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-08137-1

By:

Koenig, Leopold;
Juglair, Laurent;
Tao, Thi Phuong;
Fischer, Susanne;
Clausen, Inga;
Imhof-Jung, Sabine;
Janssen, Niels;
Mader, Robert;
Marbach, Daniel;
Niewoehner, Jens;
Winter, Annika;
Schubert, Desirée

Publication type:

Article

Immune response recalibration using immune therapy and biomimetic nano-therapy against high-grade gliomas and brain metastases.

Published in:

Asian Journal of Pharmaceutical Sciences, 2025, v. 20, n. 2, p. 1, doi. 10.1016/j.ajps.2025.101021

By:

Sandhbor, Puja;
John, Geofrey;
Bhat, Sakshi;
Goda, Jayant S.

Publication type:

Article

Development of an Anchor Bispecific Nanoantibody to Improve the Efficiency of Antigen Immobilization and Detection in a Well of a Polystyrene Plate.

Published in:

Doklady Biochemistry & Biophysics, 2025, v. 521, n. 1, p. 192, doi. 10.1134/S1607672924601525

By:

Tillib, S. V.;
Panasyuk, M. V.;
Goryaynova, O. S.;
Ivanova, T. I.

Publication type:

Article

Using Pharmacokinetic and Pharmacodynamic Analysis to Optimize the Dosing Regimens of Fanastomig (EMB‐02) in Patients With Advanced Solid Tumors.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 5, p. 975, doi. 10.1002/psp4.70011

By:

Jiang, Chengjun;
Ren, Fang;
Zhang, Mingfei;
Lu, Qiaoyang;
Zeng, Shuqi;
Yang, Guang;
Zhu, Yonghong

Publication type:

Article

Outcomes of elderly patients with relapsed refractory multiple myeloma (RRMM) treated with teclistamab: a multicenter study from the U.S. Multiple Myeloma Immunotherapy Consortium.

Published in:

Blood Cancer Journal, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41408-025-01297-7

By:

Pasvolsky, Oren;
Dima, Danai;
Feng, Lei;
Dong, Wenli;
Richards, Tiffany;
Davis, James A.;
Afrough, Aimaz;
Vazquez-Martinez, Mariola;
Sannareddy, Aishwarya;
Goel, Utkarsh;
Banerjee, Rahul;
Khouri, Jack;
Cervoni, Frances;
Gaballa, Mahmoud R.;
Lieberman-Cribbin, Alex;
Rana, Masooma Shifa;
Julian, Kelley;
Ferreri, Christopher J.;
Shune, Leyla;
DeJarnette, Shaun

Publication type:

Article

Bispecific antibodies combined with chemotherapy in solid tumor treatment, the path forward?

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1568724

By:

Yan, Yici;
Yuan, Jing;
Peng, Yanyang;
Zhou, Chenxi;
Liu, Xinbo;
Sun, Leitao;
Song, Qiaoling

Publication type:

Article

Effectiveness and safety of teclistamab for relapsed or refractory multiple myeloma: a systematic review and meta-analysis.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1565407

By:

Li, Wenze;
Zhao, Defeng;
Jiao, Yu;
Dong, Weilin;
Wang, Ziyi;
Yan, Xiaojing

Publication type:

Article

Population Pharmacokinetics of Tarlatamab, a Half-Life Extended DLL3-Directed Bispecific T-Cell Engager in Patients with Previously Treated Small Cell Lung Cancer.

Published in:

Clinical Pharmacokinetics, 2025, v. 64, n. 5, p. 729, doi. 10.1007/s40262-025-01499-z

By:

Kong, Stephanie;
Minocha, Mukul;
Chen, Po-Wei;
Martinez, Pablo;
Anderson, Erik S.;
Parkes, Amanda;
Houk, Brett E.;
Lin, Chih-Wei

Publication type:

Article

Research advances in FGL1 /LAG3 for cancer diagnosis and treatment: From basics to clinical practice.

Published in:

Journal of Cancer Research & Therapeutics, 2025, v. 21, n. 2, p. 344, doi. 10.4103/jcrt.jcrt_2674_23

By:

Hu, Keyao;
Zhang, Guiming;
Niu, Haitao;
Sun, Lijiang

Publication type:

Article

Application and future prospects of bispecific antibodies in the treatment of non-small cell lung cancer.

Published in:

Cancer Biology & Medicine, 2025, v. 22, n. 4, p. 348, doi. 10.20892/j.issn.2095-3941.2024.0470

By:

Junxu Wen;
Wenxing Cui;
Xiaoyan Yin;
Yu Chen;
Ailing Liu;
Qian Wang;
Xiangjiao Meng

Publication type:

Article

Recent Advances in Immune Checkpoint Inhibitors for Triple-Negative Breast Cancer.

Published in:

ImmunoTargets & Therapy, 2025, v. 14, p. 339, doi. 10.2147/ITT.S495751

By:

Corti, Chiara;
Koca, Beyza;
Rahman, Tasnim;
Mittendorf, Elizabeth A;
Tolaney, Sara M

Publication type:

Article

Perspectives of Healthcare Providers and Patients with Relapsed/Refractory Multiple Myeloma on Treatment Priorities and Novel Therapies.

Published in:

Patient Preference & Adherence, 2025, v. 18, p. 1089, doi. 10.2147/PPA.S496106

By:

Ailawadhi, Sikander;
Biru, Yelak;
Clavreul, Solène;
Miguel, Maite San;
Cormier, Nicolas;
Efebera, Yvonne;
Merz, Maximilian;
Sato, Anna;
Zeanah, Cathy;
Watkins, Jack L;
Farrell, James;
Goldman, Erinn Hoag;
Popat, Rakesh

Publication type:

Article

Contemporary management of diffuse large B-cell lymphoma in Japan.

Published in:

Expert Review of Anticancer Therapy, 2025, v. 25, n. 5, p. 551, doi. 10.1080/14737140.2025.2490283

By:

Miura, Katsuhiro;
Takahashi, Hiromichi;
Nishimaki-Watanabe, Haruna;
Hamada, Takashi;
Uchiike, Akihiro;
Tsutsumi, Daisuke;
Ohtake, Shimon;
Iizuka, Kazuhide;
Koike, Takashi;
Kurihara, Kazuya;
Endo, Toshihide;
Hayama, Tatsuya;
Nakagawa, Masaru;
Iriyama, Noriyoshi;
Hatta, Yoshihiro;
Nakamura, Hideki

Publication type:

Article

Production of a bispecific antibody targeting TNF-α and C5a in Pichia pastoris and its therapeutic potential in rheumatoid arthritis.

Published in:

Biotechnology Letters, 2020, v. 42, n. 4, p. 557, doi. 10.1007/s10529-020-02830-3

By:

Chen, Jin;
He, Zhonghui;
Fan, Yuran;
Zhou, Xiaodong;
Li, Lujun;
Liu, Mengyuan

Publication type:

Article

Epsilon-caprolactone-modified polyethylenimine as a genetic vehicle for stem cell-based bispecific antibody and exosome synergistic therapy.

Published in:

Regenerative Biomaterials, 2023, v. 10, p. 1, doi. 10.1093/rb/rbac090

By:

Tan, Yan;
Cai, Jiali;
Wang, Zhiyong

Publication type:

Article

Investigation of the therapeutic potential of recombinant bispecific bivalent anti-PD-L1/VEGF nanobody in inhibition of angiogenesis.

Published in:

Immunopharmacology & Immunotoxicology, 2023, v. 45, n. 2, p. 197, doi. 10.1080/08923973.2022.2131571

By:

Hassanzadeh Eskafi, Ayda;
Oghalaei, Akbar;
Mahboudi, Fereidoun;
Ghaderi, Hajarsadat;
Behdani, Mahdi;
Shoari, Alireza;
Kazemi-Lomedasht, Fatemeh

Publication type:

Article

Targeted immunotherapy: harnessing the immune system to battle multiple myeloma.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-01818-6

By:

Xu, Limei;
Wen, Caining;
Xia, Jiang;
Zhang, Hao;
Liang, Yujie;
Xu, Xiao

Publication type:

Article

ЛЕЧЕНИЕ НА НОВОДИАГНОСТИЦИРАНИ ПАЦИЕНТИ С МИЕЛОМНА БОЛЕСТ - МИНАЛО, НАСТОЯЩЕ, БЪДЕЩЕ

Published in:

General Medicine / Obsta Medicina, 2024, v. 26, n. 6, p. 29

By:

Геров, В.;
Герова, Д.

Publication type:

Article

МАКУЛНА ДЕГЕНЕРАЦИЯ, СВЪРЗАНА С ВЪЗРАСТТА – НОВОСТИ В ТЕРАПИЯТА.

Published in:

General Medicine / Obsta Medicina, 2024, v. 26, n. 1, p. 51

By:

Антонова, Д.;
Видинова, Х.

Publication type:

Article

Clinical experience with tebentafusp in metastatic uveal melanoma.

Published in:

Oncolog-Hematolog, 2024, n. 69, p. 23

By:

Bradea, Raul;
Burz, Claudia

Publication type:

Article

Culture media and format alter cellular composition and barrier integrity of porcine colonoid-derived monolayers.

Published in:

Tissue Barriers, 2024, v. 12, n. 2, p. 1, doi. 10.1080/21688370.2023.2222632

By:

Barnett, Alicia M.;
Mullaney, Jane A.;
McNabb, Warren C.;
Roy, Nicole C.

Publication type:

Article

Targeting EGFR Exon 20 Insertion-mutated Cancers – New Perspectives in Head and Neck Cancers – Lessons to Learn from Non-small Cell Carcinoma (NSCLC).

Published in:

Medicina Moderna, 2022, v. 29, n. 3, p. 181, doi. 10.31689/rmm.2022.29.3.181

By:

MIRESTEAN, Camil Ciprian;
IANCU, Roxana Irina;
IANCU, Dragos Teodor

Publication type:

Article

Hydrophobic Interaction Chromatography (HIC) for the Characterization of Therapeutic Monoclonal Antibodies and Related Products, Part 1: Theoretical Aspects.

Published in:

LC-GC Europe, 2021, v. 34, n. 3, p. 101

By:

Fekete, Szabolcs;
Murisier, Amarande;
Sandra, Koen;
Guillarme, Davy

Publication type:

Article

Bispecific antibodies in multiple myeloma.

Published in:

Acta Haematologica Polonica, 2025, v. 56, n. 1, p. 39, doi. 10.5603/ahp.104091

By:

Bieliński, Krzysztof;
Puła, Bartosz

Publication type:

Article

Shaping the future of multiple myeloma therapy: innovations in bispecific antibodies and emerging strategies in Poland.

Published in:

Acta Haematologica Polonica, 2025, v. 56, n. 1, p. 1, doi. 10.5603/ahp.105013

By:

Dytfeld, Dominik;
Jakubowiak, Andrzej

Publication type:

Article

Bispecific antibodies in relapsed/refractory diffuse large B-cell lymphoma.

Published in:

Acta Haematologica Polonica, 2024, v. 55, n. 4, p. 186, doi. 10.5603/ahp.100752

By:

Danecki, Michał;
Jurczak, Wojciech

Publication type:

Article

A breakthrough in lymphoma therapy.

Published in:

Acta Haematologica Polonica, 2024, v. 55, n. 4, p. 1, doi. 10.5603/ahp.102328

By:

Puła, Bartosz

Publication type:

Article

Current knowledge and management of primary mediastinal large B-cell lymphoma.

Published in:

Acta Haematologica Polonica, 2024, v. 55, n. 3, p. 137, doi. 10.5603/ahp.99320

By:

Szydłowska, Sylwia;
Gil, Lidia;
Dworacki, Grzegorz;
Balcerzak, Andrzej

Publication type:

Article

Subcutaneous Epcoritamab in Patients With Relapsed or Refractory Large B-Cell Lymphoma (EPCORE NHL-1): Pivotal Results From a Phase 2 Study.

Published in:

Acta Haematologica Polonica, 2022, v. 53, n. A, p. 44

By:

Jurczak, Wojciech;
Thieblemont, Catherine;
Phillips, Tycel;
Ghesquieres, Herve;
Cheah, Chan Y.;
Roost, Michael;
Cunningham, David;
Young Rok Do;
Feldman, Tatyana;
Gasiorowski, Robin;
Tae Min Kim;
Lewis, David John;
Van der Poel, Marjolein;
Limei Poon, Michelle;
Doerr, Thomas;
Kilavuz, Nurgul;
Menghui Chen;
Sacchi, Mariana;
Elliott, Brian;
Hutchings, Martin

Publication type:

Article

Emicizumab in severe hemophilia A.

Published in:

Acta Haematologica Polonica, 2021, v. 52, n. 4, p. 422, doi. 10.5603/AHP.2021.0079

By:

Windyga, Jerzy

Publication type:

Article

Emicizumab in severe hemophilia A.

Published in:

Acta Haematologica Polonica, 2021, v. 52, n. 4, p. 422, doi. 10.5603/AHP.2021.0079

By:

Windyga, Jerzy

Publication type:

Article

Population dynamics of immunological synapse formation induced by bispecific T cell engagers predict clinical pharmacodynamics and treatment resistance.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.83659

By:

Can Liu;
Jiawei Zhou;
Kudlacek, Stephan;
Qi, Timothy;
Dunlap, Tyler;
Yanguang Cao

Publication type:

Article

Treatment strategies for patients with HER2-positive gastric cancer.

Published in:

Cancer Biology & Medicine, 2023, v. 20, n. 12, p. 934, doi. 10.20892/j.issn.2095-3941.2023.0480

By:

Feixue Wang;
Yi Ba

Publication type:

Article

Bispecific antibodies targeting immunomodulatory checkpoints for cancer therapy.

Published in:

Cancer Biology & Medicine, 2023, v. 20, n. 3, p. 181, doi. 10.20892/j.issn.2095-3941.2023.0002

By:

Tiancheng Zhang;
Youpei Lin;
Qiang Gao

Publication type:

Article

Targeting the EGF receptor family in non-small cell lung cancer—increased complexity and future perspectives.

Published in:

Cancer Biology & Medicine, 2022, v. 19, n. 11, p. 1543, doi. 10.20892/j.issn.2095-3941.2022.0540

By:

Boch, Tobias;
Köhler, Jens;
Janning, Melanie;
Loges, Sonja

Publication type:

Article

Discovery of natural bispecific antibodies: Is psoriasis induced by a toxigenic Corynebacterium simulans and maintained by CIDAMPs as autoantigens?

Published in:

Experimental Dermatology, 2024, v. 33, n. 1, p. 1, doi. 10.1111/exd.15014

By:

Schröder, Jens‐Michael

Publication type:

Article

Translational drug discovery and development with the use of tissue‐relevant biomarkers: Towards more physiological relevance and better prediction of clinical efficacy.

Published in:

Experimental Dermatology, 2020, v. 29, n. 1, p. 4, doi. 10.1111/exd.13942

By:

Florian, Peter;
Flechsenhar, Klaus R.;
Bartnik, Eckart;
Ding‐Pfennigdorff, Danping;
Herrmann, Matthias;
Bryce, Paul J.;
Nestle, Frank O.

Publication type:

Article

A novel T cell-redirecting anti-GPRC5D × CD3 bispecific antibody with potent antitumor activity in multiple myeloma preclinical models.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-55143-0

By:

Tomita, Urara;
Ishimoto, Yoko;
Ri, Masaki;
Kawase, Yumi;
Hizukuri, Yoshiyuki;
Maru, Chikako;
Nanai, Kayoko;
Nakamura, Ryuichi;
Nakayama, Makiko;
Oguchi-Oshima, Keiko;
Sumi, Hiroyuki;
Ohtsuka, Toshiaki;
Iida, Shinsuke;
Agatsuma, Toshinori

Publication type:

Article

Effective clearance of rituximab-resistant tumor cells by breaking the mirror-symmetry of immunoglobulin G and simultaneous binding to CD55 and CD20.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-45491-8

By:

Lee, Sang Min;
Min, Sung-Won;
Kwon, Hyeong Sun;
Bae, Gong-Deuk;
Jung, Ji Hae;
Park, Hye In;
Lee, Seung Hyeon;
Lim, Chung Su;
Ko, Byoung Joon;
Lee, Ji Chul;
Jung, Sang Taek

Publication type:

Article

Construction of IgG–Fab<sup>2</sup> bispecific antibody via intein-mediated protein trans-splicing reaction.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-43110-0

By:

Yamada, Risa;
Nakahara, Ishin;
Kumagai, Izumi;
Asano, Ryutaro;
Nakanishi, Takeshi;
Makabe, Koki

Publication type:

Article

Molecular insights into recognition of GUCY2C by T-cell engaging bispecific antibody anti-GUCY2CxCD3.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-40467-0

By:

Rampuria, Pragya;
Mosyak, Lidia;
Root, Adam R.;
Svenson, Kristine;
Agostino, Michael J.;
LaVallie, Edward R.

Publication type:

Article

Developing a dual VEGF/PDL1 inhibitor based on high-affinity scFv heterodimers as an anti-cancer therapeutic strategy.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-39076-8

By:

Tzuri, Noam;
Yegodayev, Ksenia M.;
Novoplansky, Ofra;
Elkabets, Moshe;
Aharoni, Amir;
Papo, Niv

Publication type:

Article

N-glycans from serum IgG and total serum glycoproteins specific for endometriosis.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-37421-5

By:

Kovács, Zsuzsanna;
Reidy, Fiona;
Glover, Louise;
McAuliffe, Fionnuala M.;
Stockmann, Henning;
Kilbane, Mark T.;
Twomey, Patrick J.;
Peters, Maire;
Saare, Merli;
Rudd, Pauline M.;
Utt, Meeme;
Wingfield, Mary;
Salumets, Andres;
Saldova, Radka

Publication type:

Article