Works about BIOINFORMATICS

Results: 5000

Revealing the significance of tissue-resident memory T cells in lung adenocarcinoma through bioinformatic analysis and experimental validation.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1600863

By:

Li, Zhuoqi;
Tian, Mei;
Yang, Yuanhui;
Wang, Yuanyuan;
Zhang, Lu;
Huang, Fujing;
Wen, Xiao;
Yin, Xiaoshu;
Lin, Xiaoyan;
Tian, Yuan

Publication type:

Article

Integrative bioinformatics and machine learning approaches reveal oxidative stress and glucose metabolism related genes as therapeutic targets and drug candidates in Alzheimer's disease.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1572468

By:

Noor, Fatima;
Aslam, Sidra;
Piras, Ignazio S.;
Tremblay, Cecilia;
Beach, Thomas G.;
Serrano, Geidy E.

Publication type:

Article

Prognostic and Immunotherapeutic Role of TACC3 in Pancancer and Its Impact on Proliferation and Docetaxel Resistance in Lung Adenocarcinoma.

Published in:

Oncology, 2025, v. 103, n. 7, p. 628, doi. 10.1159/000542450

By:

Xu, Jianyu;
Zhu, Ying;
Liu, Qian;
Xu, Chenchang;
Wang, Wenjuan;
Sun, Jiantong;
Ding, Xinyuan;
Liu, Biao;
Chen, Lei

Publication type:

Article

Evaluation of the antibacterial efficacy of combinations of Garcinia mangostana, Curcuma comosa, and Acanthus ebracteatus for acne vulgaris treatment: in Silico and in vitro validation.

Published in:

BMC Complementary Medicine & Therapies, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12906-025-04997-6

By:

Eawsakul, Komgrit;
Bunluepuech, Kingkan;
Wisessombat, Sueptrakool

Publication type:

Article

Unveiling the anticancer potential of Curcuma amada rhizome extract against prostate cancer through computational and experimental approaches.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-10761-0

By:

Priyadarshini, Arpita;
Mohanty, Debajani;
Mohanty, Swagat;
Kerry, Rout George;
Sahoo, Ambika;
Dash, Biswabhusan;
Panda, Pratap Chandra;
Nayak, Sanghamitra;
Ray, Asit;
Jena, Sudipta

Publication type:

Article

Determining the origin of genome aberrations improves the positive predictive value of NIPT for 22q11.2 deletion syndrome.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-10446-8

By:

Xiang, Jiale;
Sun, Xiangzhong;
Peng, Jiguang;
Zhang, Hongfu;
Shen, Jiankun;
Li, Jingrou;
Li, Hongyu;
Hu, Lanping;
Zhang, Jingjing;
Zhou, Shihao;
Xu, Sihu;
Yang, Yun;
He, Jun;
Peng, Zhiyu

Publication type:

Article

Integrated bioinformatics and experimental analysis of mitochondrial-associated membrane function and mechanism in acute respiratory distress syndrome.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-10405-3

By:

Zhou, Yanqiong;
Chen, Qiuying;
Wang, Xiaoxia;
Lv, Kaimin;
Huang, Hui;
Feng, Jifeng;
Luo, Bijun

Publication type:

Article

"Cyclic nucleotides in plants: from obscure messengers to central regulators".

Published in:

Frontiers in Plant Science, 2025, p. 1, doi. 10.3389/fpls.2025.1618243

By:

Świeżawska-Boniecka, Brygida;
Szmidt-Jaworska, Adriana

Publication type:

Article

Constructing inflammatory bowel disease diagnostic models based on k-mer and machine learning.

Published in:

Frontiers in Microbiology, 2025, p. 1, doi. 10.3389/fmicb.2025.1578005

By:

Li, Liwei;
Liu, Zheng;
Qin, Jiamin;
Xiong, Guang;
Yang, Chongze;
Cai, Fuqing;
Huang, Jiean

Publication type:

Article

LncRNA HOXB-AS4 Promotes Tumor Malignant Phenotype in Head and Neck Squamous Cell Carcinoma and Serves as a Prognosis Marker.

Published in:

Journal of Cancer, 2025, v. 16, n. 9, p. 2997, doi. 10.7150/jca.111037

By:

Shanshan Lv;
Jie Guo;
Lin Du;
Yanwei Luo;
Hao Tian;
Yan Liu

Publication type:

Article

ESCO2 promotes the proliferation of hepatocellular carcinoma through the PI3K/AKT/ mTOR signaling pathway.

Published in:

Journal of Cancer, 2025, v. 16, n. 9, p. 2929, doi. 10.7150/jca.112087

By:

Dapeng Chen;
Yue Huang;
Weixin Zhang;
Youcheng Zhang;
Yi Bai;
Yamin Zhang

Publication type:

Article

Loss of LIMCH1 predicts poor prognosis in patients with surgically resected Lung Adenocarcinoma: A study based on Immunohistochemical Analysis and Bioinformatics.

Published in:

Journal of Cancer, 2021, v. 12, n. 1, p. 181, doi. 10.7150/jca.47883

By:

He Cao;
Jing Zhao;
Zhen Chen;
Wenjia Sun;
Kexin Ruan;
Jianya Zhou;
Jianying Zhou

Publication type:

Article

Transcriptomic profiling and bioinformatic insights into myocardial injury following aneurysmal subarachnoid hemorrhage.

Published in:

Frontiers in Neurology, 2025, p. 1, doi. 10.3389/fneur.2025.1492398

By:

Wu, Zuoli;
He, Wenbo;
Ye, Weihao;
Xu, Shang;
Wei, Shengwei;
Huang, Baozi;
Li, Pingping;
Tang, Yanyan;
Qin, Chao;
Liu, Ying;
Ye, Ziming

Publication type:

Article

Shared pathogenesis in polycystic ovaries and rheumatoid arthritis: an analysis of key genes and pathways.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1554139

By:

Ji, Yingying;
Xia, Pengcheng;
Wang, Yan;
Liu, Yang;
Wang, Feng;
Sun, Fenggang;
Feng, Qiang;
Ni, Qingbin;
Li, Yi

Publication type:

Article

Mapping Molecular Pathways of Multiple Sclerosis: A Gene Prioritization and Network Analysis of White Matter Pathology Transcriptomics.

Published in:

Annals of Neurology, 2025, v. 98, n. 1, p. 67, doi. 10.1002/ana.27216

By:

Abbadessa, Gianmarco;
Nagano, Ai;
Hametner, Simon;
Howell, Owain;
Owen, David;
Papadaki, Artemis;
Srivastava, Prashant;
Bonavita, Simona;
Magliozzi, Roberta;
Reynolds, Richard;
Rizig, Mie;
Nicholas, Richard

Publication type:

Article

A novel intronic variant in the ASAH1 gene enhances aberrant splicing, causing spinal muscular atrophy with progressive myoclonic epilepsy.

Published in:

Italian Journal of Pediatrics, 2025, v. 51, n. 1, p. 1, doi. 10.1186/s13052-025-02058-9

By:

Bai, Jinli;
Li, Ping;
Jiao, Hui;
Jin, Yuwei;
Wang, Hong;
Jiang, Qinglin;
Song, Fang;
Peng, Xiaoyin;
Qu, Yujin

Publication type:

Article

Early diagnosed Zaki syndrome: identification of two novel WLS variants and a literature review.

Published in:

Italian Journal of Pediatrics, 2025, v. 51, n. 1, p. 1, doi. 10.1186/s13052-025-02067-8

By:

Tian, Anran;
Li, Sujuan;
Liang, Furong;
Yao, Minglan;
Mostafavi, Niusha;
Li, Yingying;
Luo, Xiaoping;
Zhang, Cai

Publication type:

Article

Machine learning assists regulated cell death crucial biomarker selection in adenocarcinoma of the lung: biological data testing and cell assay determination.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02793-9

By:

Ning, Han;
Jiang, Ying;
Zheng, Mengli;
Yang, Gao;
Ma, Lianjun;
Zhao, Yachao

Publication type:

Article

Periodontal Ligament Reactions to Orthodontic Force: A Transcriptomic Study on Maxillary and Mandibular Human Premolars.

Published in:

Journal of Periodontal Research, 2025, v. 60, n. 5, p. 484, doi. 10.1111/jre.13352

By:

Zhao, Zuodong;
Tarce, Mihai;
Georgopoulou, Maria;
Zong, Chen;
Van Holm, Wannes;
Attanasio, Catia;
Pedano, Mariano Simón;
de Llano‐Pérula, Maria Cadenas

Publication type:

Article

Unveiling the Therapeutic Potential of Piper chaba Hunter: Computational Approaches Shed Light on Targeting Proteins in Alzheimer's Disease.

Published in:

BioMed Research International, 2025, v. 2025, p. 1, doi. 10.1155/bmri/8892801

By:

Rahi, Md. Sifat;
Rahman, Md. Shahedur;
Meem, Rima Islam;
Shimul, Md. Ebrahim Khalil;
Farnaj, Nahid;
Kabir, Md. Humaun;
Ahmed, Fee Faysal;
Parvez, Md. Anowar Khasru;
Huq, Md. Amdadul;
Kabir, Tabassum;
Harrath, Abdel Halim;
Hasan, Mahadi;
Rahman, Md. Ataur;
Siddique, Muhammad Hussnain

Publication type:

Article

LAMA3 overexpression enhances proliferation, migration and invasion in esophageal squamous cell carcinoma based on bioinformatics and experimental validation.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-08026-x

By:

Wu, Xia;
Li, Qian;
Wang, Junbin;
Li, Lei;
Zuo, Mingtang;
Cheng, Yufeng

Publication type:

Article

Bioinformatics analysis identifies BST1 as a potential therapeutic target linked to neutrophil extracellular traps in patients with acute liver failure.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-05792-6

By:

Tao, Mengyu;
Fu, Jiwei;
Wu, Xiaoping

Publication type:

Article

Integrated analysis of WGCNA and machine learning identified diagnostic biomarkers in trauma-induced coagulopathy.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-10323-4

By:

Chen, Qingsong;
Li, Tao;
Zhang, Tao;
Zhou, Yue;
Huang, Weifeng;
Li, Hui;
Shi, Li;
Li, Jianxiao;
Zhang, Qi;
Ma, Man;
Wang, Pan;
Hu, Hui;
Wei, Gongbin;
Xiang, Jiangxia;
Cheng, Yuan;
Yang, Jun;
Huang, Guangbin;
Li, Yongming;
Du, Dingyuan

Publication type:

Article

Exploring the role of inflammation, immunity, and metabolism in colorectal cancer via mendelian randomization approach.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-10318-1

By:

Zhou, Li;
Liao, Mingjing;
Zhang, Leilei;
Peng, Tingting;
Han, Chengyun;
Zeng, Qiang;
Huan, Xuanrong;
Dai, Anya;
Gao, Zhongyan;
Li, Jie;
Tang, Jia;
Chen, Jie;
Li, Yuan;
Zhang, Jiwang

Publication type:

Article

Identification and validation of endoplasmic reticulum autophagy-related potential biomarkers in periodontitis.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-08180-2

By:

Wang, Ruyue;
Hu, Jinyue;
Sun, Qing;
Guo, Shuixiang;
Zhang, Gege;
Lu, Ao;
Liu, Shuo;
Yang, Xue;
Wang, Lina

Publication type:

Article

Traditional Unani Ingredient Bombyx mori Exhibits Therapeutic Promise in IHD.

Published in:: Indian Practitioner, 2025, v. 78, n. 6, p. 51
Publication type:: Article

Cyclotron-Powered Molecular Nanotechnology in Precision Oncology, A Systematic Insight into Emerging Theranostic Frontiers for Precision-Guided Cancer Therapeutics.

Published in:

Indian Practitioner, 2025, v. 78, n. 6, p. 20

By:

Khan, Mohammad Nadeem;
Kumar, Ashok

Publication type:

Article

Integrative bioinformatics analysis of pyroptosis-related genes and immune infiltration patterns in childhood asthma.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1557709

By:

Lian, Di;
Lin, Chenye;
Xie, Meiling;
Wei, JianXing;
Huang, Xueling;
Lian, Ke;
Tang, Qiuyu

Publication type:

Article

PI3K/AKT signaling pathway plays an important role in the pathogenesis of metabolic dysfunction-associated steatotic liver disease.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-07612-3

By:

Shao, Cuiping;
Xu, Youqing

Publication type:

Article

LassoPred: a tool to predict the 3D structure of lasso peptides.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60544-4

By:

Ouyang, Xingyu;
Ran, Xinchun;
Xu, Han;
Al-Abssi, Runeem;
Zhao, Yi-Lei;
Link, A. James;
Yang, Zhongyue J.

Publication type:

Article

Drug Repurposing for Targeting ISL LIM Homeobox 2 in Treatment of Endometriosis: A Computational Study.

Published in:

International Journal of Fertility & Sterility, 2025, v. 19, n. 3, p. 277, doi. 10.22074/ijfs.2025.2009299.1516

By:

Mahdian, Soodeh;
Favaedi, Raha;
Mikaeeli, Gelareh;
Moini, Ashraf;
Shahhoseini, Maryam

Publication type:

Article

Evaluating the Effectiveness of Various Small RNA Alignment Techniques in Transcriptomic Analysis by Examining Different Sources of Variability Through a Multi-Alignment Approach.

Published in:

Methods & Protocols, 2025, v. 8, n. 3, p. 65, doi. 10.3390/mps8030065

By:

Zhao, Xinwei;
Korsching, Eberhard

Publication type:

Article

Exploring the potential anticancer targets and mechanistic pathways of Elsholtzia densa essential oil based on network pharmacology.

Published in:

Journal of Asian Natural Products Research, 2025, v. 27, n. 7, p. 1038, doi. 10.1080/10286020.2024.2446294

By:

Wang, Qian;
Wang, Xiao-Ying;
Tao, Jin;
Nie, Jin-Tao;
Zhou, Yi-Han;
Huang, Jing;
Zhao, Jia-Yuan;
Wang, Ya-Nan

Publication type:

Article

Three new terpenoid derivatives from the deep-sea-derived fungus Aspergillus sydowii DFFSCS007.

Published in:

Journal of Asian Natural Products Research, 2025, v. 27, n. 7, p. 1005, doi. 10.1080/10286020.2024.2443086

By:

Ren, Xu-Meng;
Wu, Ke-Yue;
Qi, Shu-Hua

Publication type:

Article

Applications and Prospects of Single‐Cell RNA Sequencing and Spatial Transcriptomics in Cervical Cancer.

Published in:

BioMed Research International, 2025, v. 2025, p. 1, doi. 10.1155/bmri/1532745

By:

Wang, Yifu;
Yang, Li;
Liu, Yunzhi;
Ma, Huangrong;
Cai, Miaoying;
Liang, Chunyu;
Zhang, Li;
Su, Zezhuo;
Xu, Zhiyuan;
Lopez-Camarillo, Cesar

Publication type:

Article

Validation of Biomarkers and Immunotherapy With Crohn's Disease Using WGCNA and Two‐Sample Mendelian Randomization Study.

Published in:

Gastroenterology Research & Practice, 2025, v. 2025, p. 1, doi. 10.1155/grp/8194480

By:

Hu, Cong;
Nong, Shuxiong;
Liu, Chenang;
Chen, Yongfeng;
Liao, Chilin;
Wu, Meng;
Toyokawa, Tatsuya

Publication type:

Article

Clinical Connections.

Published in:: Arthritis & Rheumatology, 2025, v. 77, n. 7, p. 1, doi. 10.1002/art.43282
Publication type:: Article

Genome‐Wide Aggregated Trans Effects Analysis Identifies Genes Encoding Immune Checkpoints as Core Genes for Rheumatoid Arthritis.

Published in:

Arthritis & Rheumatology, 2025, v. 77, n. 7, p. 817, doi. 10.1002/art.43125

By:

Spiliopoulou, Athina;
Iakovliev, Andrii;
Plant, Darren;
Sutcliffe, Megan;
Sharma, Seema;
Cubuk, Cankut;
Lewis, Myles;
Pitzalis, Costantino;
Barton, Anne;
McKeigue, Paul M.

Publication type:

Article

Unraveling the Mechanisms of Active Saponins from Rhizoma Anemarrhenae Against Ferroptosis in Alzheimer's Disease: Integrating Network Pharmacology, Cell Membrane Chromatography, and Experimental Validation.

Published in:

American Journal of Chinese Medicine, 2025, v. 53, n. 4, p. 1119, doi. 10.1142/S0192415X25500429

By:

Peng, Jing;
Lu, Zhongjiao;
Sai, Fangfang;
Min, Liang;
Zhang, Xu;
Ru, Dan;
Song, Yaying;
Wei, Xin;
Gao, Li;
Wang, Hai-Qiao

Publication type:

Article

Identifying CDCA4 as a Radiotherapy Resistance-Associated Gene in Colorectal Cancer by an Integrated Bioinformatics Analysis Approach.

Published in:

Genes, 2025, v. 16, n. 6, p. 696, doi. 10.3390/genes16060696

By:

Chen, Lin;
Gao, Yawei;
Hu, Zhiqing;
Si, Jingwen;
Zhang, Yuchao;
Cai, Qingping

Publication type:

Article

Gene Expression Profiling in Rat Tissues of Different Status of Insulin Sensitivity.

Published in:: Journal of Systems Science & Information, 2011, v. 9, n. 1, p. 79
Publication type:: Article

Potential therapeutic significance of resveratrol for autism spectrum disorders based on clinical bioinformatics.

Published in:

Chinese Nursing Research, 2024, v. 38, n. 21, p. 3768, doi. 10.12102/j.issn.1009-6493.2024.21.002

By:

LYU Yanhua;
ZHONG Xiaoyun;
WANG Kanglong;
ZHAO Hongxia;
YU Qi

Publication type:

Article

Informare! Der Weg zum WISSEN. Digital!

Published in:: ABI Technik, 2011, v. 31, n. 1, p. 1
Publication type:: Article

Genetic code flexibility in microorganisms: novel mechanisms and impact on physiology.

Published in:

Nature Reviews Microbiology, 2015, v. 13, n. 11, p. 707, doi. 10.1038/nrmicro3568

By:

Ling, Jiqiang;
O'Donoghue, Patrick;
Söll, Dieter

Publication type:

Article

The abundance and variety of carbohydrate-active enzymes in the human gut microbiota.

Published in:

Nature Reviews Microbiology, 2013, v. 11, n. 7, p. 497, doi. 10.1038/nrmicro3050

By:

Kaoutari, Abdessamad El;
Armougom, Fabrice;
Gordon, Jeffrey I.;
Raoult, Didier;
Henrissat, Bernard

Publication type:

Article

Genome architecture and global gene regulation in bacteria: making progress towards a unified model?

Published in:

Nature Reviews Microbiology, 2013, v. 11, n. 5, p. 349, doi. 10.1038/nrmicro3007

By:

Dorman, Charles J.

Publication type:

Article

Genomic sequencing of uncultured microorganisms from single cells.

Published in:

Nature Reviews Microbiology, 2012, v. 10, n. 9, p. 631, doi. 10.1038/nrmicro2857

By:

Lasken, Roger S.

Publication type:

Article

Next-generation training.

Published in:: Nature Reviews Microbiology, 2012, v. 10, n. 7, p. 439, doi. 10.1038/nrmicro2830
Publication type:: Article

Bacterial toxins: The touch of death.

Published in:

Nature Reviews Microbiology, 2011, v. 9, n. 1, p. 3, doi. 10.1038/nrmicro2495

By:

Jermy, Andrew

Publication type:

Article

Genome annotation: man versus machine.

Published in:

Nature Reviews Microbiology, 2010, v. 8, n. 11, p. 762, doi. 10.1038/nrmicro2462

By:

Petty, Nicola K.

Publication type:

Article