Works matching DE "BIOCHEMICAL mechanism of action"

Results: 3683

Advancement in tumor treating fields of mechanism, clinical applications, and future directions.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02861-0

By:

Zang, Meiqi;
Zhu, Song;
Niu, Qiang

Publication type:

Article

Staphylococcus epidermidis bacteriocin A37 kills natural competitors with a unique mechanism of action.

Published in:

ISME Journal: Multidisciplinary Journal of Microbial Ecology, 2024, v. 18, n. 1, p. 1, doi. 10.1093/ismejo/wrae044

By:

Puls, Jan-Samuel;
Winnerling, Benjamin;
Power, Jeffrey J;
Krüger, Annika M;
Brajtenbach, Dominik;
Johnson, Matthew;
Bilici, Kevser;
Camus, Laura;
Fließwasser, Thomas;
Schneider, Tanja;
Sahl, Hans-Georg;
Ghosal, Debnath;
Kubitscheck, Ulrich;
Heilbronner, Simon;
Grein, Fabian

Publication type:

Article

Promoter melting by an alternative σ, one base at a time.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 4, p. 350, doi. 10.1038/nsmb.2798

By:

Darst, Seth A;
Feklistov, Andrey;
Gross, Carol A

Publication type:

Article

Transcriptionally active chromatin recruits homologous recombination at DNA double-strand breaks.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 4, p. 366, doi. 10.1038/nsmb.2796

By:

Aymard, François;
Bugler, Beatrix;
Schmidt, Christine K;
Guillou, Emmanuelle;
Caron, Pierre;
Briois, Sébastien;
Iacovoni, Jason S;
Daburon, Virginie;
Miller, Kyle M;
Jackson, Stephen P;
Legube, Gaëlle

Publication type:

Article

New insights into ubiquitin E3 ligase mechanism.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 4, p. 301, doi. 10.1038/nsmb.2780

By:

Berndsen, Christopher E;
Wolberger, Cynthia

Publication type:

Article

Mechanism of IRSp53 inhibition and combinatorial activation by Cdc42 and downstream effectors.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 4, p. 413, doi. 10.1038/nsmb.2781

By:

Kast, David J;
Yang, Changsong;
Disanza, Andrea;
Boczkowska, Malgorzata;
Madasu, Yadaiah;
Scita, Giorgio;
Svitkina, Tatyana;
Dominguez, Roberto

Publication type:

Article

Lysine-targeting specificity in ubiquitin and ubiquitin-like modification pathways.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 4, p. 308, doi. 10.1038/nsmb.2792

By:

Mattiroli, Francesca;
Sixma, Titia K

Publication type:

Article

The mechanism of folding of Im7 reveals competition between functional and kinetic evolutionary constraints.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 3, p. 318, doi. 10.1038/nsmb.1562

By:

Friel, Claire T.;
Smith, D. Alastair;
Vendruscolo, Michele;
Gsponer, Joerg;
Radford, Sheena E.

Publication type:

Article

Precious metal.

Published in:

Nature Reviews Microbiology, 2006, v. 4, n. 6, p. 416, doi. 10.1038/nrmicro1429

By:

Tremp, Annie

Publication type:

Article

Safety evaluation of combination doxorubicin and toceranib phosphate (Palladia®) in tumour bearing dogs: a phase I dose-finding study.

Published in:

Veterinary & Comparative Oncology, 2017, v. 15, n. 3, p. 919, doi. 10.1111/vco.12232

By:

Pellin, M. A.;
Wouda, R. M.;
Robinson, K.;
Tsimbas, K.;
Kurzman, I. D.;
Biller, B. J.;
Vail, D. M.

Publication type:

Article

Moenomycin Biosynthesis: Structure and Mechanism of Action of the Prenyltransferase MoeN5.

Published in:

Angewandte Chemie, 2016, v. 128, n. 15, p. 4794, doi. 10.1002/ange.201511388

By:

Zhang, Lilan;
Chen, Chun ‐ Chi;
Ko, Tzu ‐ Ping;
Huang, Jian ‐ Wen;
Zheng, Yingying;
Liu, Weidong;
Wang, Iren;
Malwal, Satish R.;
Feng, Xinxin;
Wang, Ke;
Huang, Chun ‐ Hsiang;
Hsu, Shang ‐ Te Danny;
Wang, Andrew H. ‐ J.;
Oldfield, Eric;
Guo, Rey ‐ Ting

Publication type:

Article

Pseudiline: halogenierte, allosterische Inhibitoren des Enzyms IspD aus dem Mevalonat-unabhängigen Biosyntheseweg.

Published in:

Angewandte Chemie, 2014, v. 126, n. 8, p. 2267, doi. 10.1002/ange.201309557

By:

Kunfermann, Andrea;
Witschel, Matthias;
Illarionov, Boris;
Martin, René;
Rottmann, Matthias;
Höffken, H. Wolfgang;
Seet, Michael;
Eisenreich, Wolfgang;
Knölker, Hans ‐ Joachim;
Fischer, Markus;
Bacher, Adelbert;
Groll, Michael;
Diederich, François

Publication type:

Article

Strength Characteristics of Reef Limestone for Different Cementation Types.

Published in:

Geotechnical & Geological Engineering, 2020, v. 38, n. 1, p. 79, doi. 10.1007/s10706-019-01000-1

By:

Wang, Xing;
Shan, Huagang;
Wang, Xinzhi;
Zhu, Changqi

Publication type:

Article

Probing the function of long noncoding RNAs in the nucleus.

Published in:

Chromosome Research, 2020, v. 28, n. 1, p. 87, doi. 10.1007/s10577-019-09625-x

By:

Akkipeddi, Sajal Medha K.;
Velleca, Anthony J.;
Carone, Dawn M.

Publication type:

Article

Simulating hypoxia-induced acidic environment in cancer cells facilitates mobilization and redox-cycling of genomic copper by daidzein leading to pro-oxidant cell death: implications for the sensitization of resistant hypoxic cancer cells to therapeutic challenges

Published in:

BioMetals, 2016, v. 29, n. 2, p. 299, doi. 10.1007/s10534-016-9916-6

By:

Ullah, Mohammad;
Ahmad, Aamir;
Bhat, Showket;
Khan, Husain;
Zubair, Haseeb;
Sarkar, Fazlul;
Hadi, Sheikh

Publication type:

Article

Structural evidences for a secondary gold binding site in the hydrophobic box of lysozyme.

Published in:

BioMetals, 2015, v. 28, n. 4, p. 745, doi. 10.1007/s10534-015-9863-7

By:

Ferraro, Giarita;
Massai, Lara;
Messori, Luigi;
Cinellu, Maria;
Merlino, Antonello

Publication type:

Article

Mechanism of action of the tri-hybrid antimicrobial peptide LHP7 from lactoferricin, HP and plectasin on Staphylococcus aureus.

Published in:

BioMetals, 2014, v. 27, n. 5, p. 957, doi. 10.1007/s10534-014-9768-x

By:

Xi, Di;
Wang, Xiumin;
Teng, Da;
Mao, Ruoyu;
Zhang, Yong;
Wang, Xiaojie;
Wang, Jianhua

Publication type:

Article

Bovine and human lactoferricin peptides: chimeras and new cyclic analogs.

Published in:

BioMetals, 2014, v. 27, n. 5, p. 935, doi. 10.1007/s10534-014-9753-4

By:

Arias, Mauricio;
McDonald, Lindsey;
Haney, Evan;
Nazmi, Kamran;
Bolscher, Jan;
Vogel, Hans

Publication type:

Article

N(4)-Tolyl-2-acetylpyridine thiosemicarbazones and their platinum(II,IV) and gold(III) complexes: cytotoxicity against human glioma cells and studies on the mode of action.

Published in:

BioMetals, 2013, v. 26, n. 5, p. 677, doi. 10.1007/s10534-013-9639-x

By:

Ferraz, Karina;
Da Silva, Jeferson;
Costa, Flávia;
Mendes, Bruno;
Rodrigues, Bernardo;
Santos, Raquel;
Beraldo, Heloisa

Publication type:

Article

Comparative antimicrobial activity and mechanism of action of bovine lactoferricin-derived synthetic peptides.

Published in:

BioMetals, 2011, v. 24, n. 6, p. 1069, doi. 10.1007/s10534-011-9465-y

By:

Liu, Yifan;
Han, Feifei;
Xie, Yonggang;
Wang, Yizhen

Publication type:

Article

Synergic control of action in levodopa-naïve Parkinson's disease patients: I. Multi-finger interaction and coordination.

Published in:

Experimental Brain Research, 2020, v. 238, n. 1, p. 229, doi. 10.1007/s00221-019-05709-6

By:

de Freitas, Paulo B.;
Freitas, Sandra M. S. F.;
Reschechtko, Sasha;
Corson, Tyler;
Lewis, Mechelle M.;
Huang, Xuemei;
Latash, Mark L.

Publication type:

Article

Competition between frontal lobe functions and implicit sequence learning: evidence from the long-term effects of alcohol.

Published in:

Experimental Brain Research, 2015, v. 233, n. 7, p. 2081, doi. 10.1007/s00221-015-4279-8

By:

Virag, Marta;
Janacsek, Karolina;
Horvath, Aniko;
Bujdoso, Zoltan;
Fabo, Daniel;
Nemeth, Dezso

Publication type:

Article

Rapid eye movements to a virtual target are biased by illusory context in the Poggendorff figure.

Published in:

Experimental Brain Research, 2015, v. 233, n. 7, p. 1993, doi. 10.1007/s00221-015-4263-3

By:

Melmoth, D.;
Grant, S.;
Solomon, J.;
Morgan, M.

Publication type:

Article

Coordination of digit force variability during dominant and non-dominant sustained precision pinch.

Published in:

Experimental Brain Research, 2015, v. 233, n. 7, p. 2053, doi. 10.1007/s00221-015-4276-y

By:

Li, Ke;
Wei, Na;
Yue, Shouwei;
Thewlis, Dominic;
Fraysse, Francois;
Immink, Maarten;
Eston, Roger

Publication type:

Article

Effects of age and cognitive load on response reprogramming.

Published in:

Experimental Brain Research, 2015, v. 233, n. 3, p. 937, doi. 10.1007/s00221-014-4169-5

By:

Korotkevich, Yana;
Trewartha, Kevin;
Penhune, Virginia;
Li, Karen

Publication type:

Article

How does high-frequency sound or vibration activate vestibular receptors?

Published in:

Experimental Brain Research, 2015, v. 233, n. 3, p. 691, doi. 10.1007/s00221-014-4192-6

By:

Curthoys, I.;
Grant, J.

Publication type:

Article

Adaptation to constant-magnitude assistive forces: kinematic and neural correlates.

Published in:

Experimental Brain Research, 2011, v. 209, n. 3, p. 425, doi. 10.1007/s00221-011-2573-7

By:

Novakovic, Vladimir;
Sanguineti, Vittorio

Publication type:

Article

Exogenous hydrogen sulfide (H<sub>2</sub>S) protects against regional myocardial ischemia–reperfusion injury.

Published in:

Basic Research in Cardiology, 2006, v. 101, n. 1, p. 53, doi. 10.1007/s00395-005-0569-9

By:

Johansen, David;
Ytrehus, Kirsti;
Baxter, Gary

Publication type:

Article

Mechanisms of degradation of DNA standards for calibration function during storage.

Published in:

Applied Microbiology & Biotechnology, 2011, v. 89, n. 2, p. 407, doi. 10.1007/s00253-010-2943-2

By:

Rossmanith, Peter;
Röder, Barbara;
Frühwirth, Karin;
Vogl, Claus;
Wagner, Martin

Publication type:

Article

The mechanisms of citrate on regulating the distribution of carbon flux in the biosynthesis of uridine 5′-monophosphate by Saccharomyces cerevisiae.

Published in:

Applied Microbiology & Biotechnology, 2010, v. 86, n. 1, p. 75, doi. 10.1007/s00253-009-2287-y

By:

Yong Chen;
Shuya Li;
Jian Xiong;
Zhenjiang Li;
Jianxin Bai;
Lei Zhang;
Qi Ye;
Pingkai Ouyang;
Hanjie Ying

Publication type:

Article

Microbially induced diseases of Agaricus bisporus: biochemical mechanisms and impact on commercial mushroom production.

Published in:

Applied Microbiology & Biotechnology, 2010, v. 86, n. 1, p. 63, doi. 10.1007/s00253-010-2445-2

By:

Largeteau, Michèle;
Savoie, Jean-Michel

Publication type:

Article

Expression of BHRF1 improves survival of murine hybridoma cultures in batch and continuous modes.

Published in:

Applied Microbiology & Biotechnology, 2009, v. 83, n. 1, p. 43, doi. 10.1007/s00253-008-1820-8

By:

Juanola, Sandra;
Vives, Joaquim;
Milián, Ernest;
Prats, Eva;
Cairó, Jordi;
Gòdia, Francesc

Publication type:

Article

Purification and characterization of plantaricin LR14: a novel bacteriocin produced by Lactobacillus plantarum LR/14.

Published in:

Applied Microbiology & Biotechnology, 2008, v. 79, n. 5, p. 759, doi. 10.1007/s00253-008-1482-6

By:

Tiwari, Santosh;
Srivastava, Sheela

Publication type:

Article

Dimerization of aurein 1.2: effects in structure, antimicrobial activity and aggregation of Cândida albicans cells.

Published in:

Amino Acids, 2013, v. 44, n. 6, p. 1521, doi. 10.1007/s00726-013-1475-3

By:

Lorenzón, E.;
Sanches, P.;
Nogueira, L.;
Bauab, T.;
Cilli, E.

Publication type:

Article

Anti-inflammatory mechanism of taurine against ischemic stroke is related to down-regulation of PARP and NF-κB.

Published in:

Amino Acids, 2012, v. 42, n. 5, p. 1735, doi. 10.1007/s00726-011-0885-3

By:

Sun, Ming;
Zhao, Yumei;
Gu, Yi;
Xu, Chao

Publication type:

Article

Characterization of MRNP34, a novel methionine-rich nacre protein from the pearl oysters.

Published in:

Amino Acids, 2012, v. 42, n. 5, p. 2009, doi. 10.1007/s00726-011-0932-0

By:

Marie, Benjamin;
Joubert, Caroline;
Belliard, Corinne;
Tayale, Alexandre;
Zanella-Cléon, Isabelle;
Marin, Frédéric;
Gueguen, Yannick;
Montagnani, Caroline

Publication type:

Article

HMB supplementation: clinical and athletic performance-related effects and mechanisms of action.

Published in:

Amino Acids, 2011, v. 40, n. 4, p. 1015, doi. 10.1007/s00726-010-0678-0

By:

Zanchi, Nelo;
Gerlinger-Romero, Frederico;
Guimarães-Ferreira, Lucas;
Siqueira Filho, Mário;
Felitti, Vitor;
Lira, Fabio;
Seelaender, Marília;
Lancha, Antonio

Publication type:

Article

Design, Mechanism of Action, Bioavailability and Therapeutic Effects of Mn Porphyrin-Based Redox Modulators.

Published in:

Medical Principles & Practice, 2013, v. 22, n. 2, p. 103, doi. 10.1159/000341715

By:

Tovmasyan, Artak;
Sheng, Huaxin;
Weitner, Tin;
Arulpragasam, Amanda;
Lu, Miaomiao;
Warner, David S.;
Vujaskovic, Zeljko;
Spasojevic, Ivan;
Batinic-Haberle, Ines

Publication type:

Article

Exploring the First FDA-Approved Treatment to Delay T1D Onset: Mechanism of Action and Treatment Impact.

Published in:

Patient Care (Online), 2024, p. 1

By:

Goldman, Jennifer D.

Publication type:

Article

Survodutide, Dual Glucagon/GLP-1 Mimetic, Improves MASH in 83% of Phase 2 Trial Participants.

Published in:

Patient Care (Online), 2024, p. 1

By:

Halsey, Grace

Publication type:

Article

OncodriveROLE classifies cancer driver genes in loss of function and activating mode of action.

Published in:

Bioinformatics, 2014, v. 30, n. 17, p. i549, doi. 10.1093/bioinformatics/btu467

By:

Schroeder, Michael P.;
Rubio-Perez, Carlota;
Tamborero, David;
Gonzalez-Perez, Abel;
Lopez-Bigas, Nuria

Publication type:

Article

Mantra 2.0: an online collaborative resource for drug mode of action and repurposing by network analysis.

Published in:

Bioinformatics, 2014, v. 30, n. 12, p. 1787, doi. 10.1093/bioinformatics/btu058

By:

Carrella, Diego;
Napolitano, Francesco;
Rispoli, Rossella;
Miglietta, Mario;
Carissimo, Annamaria;
Cutillo, Luisa;
Sirci, Francesco;
Gregoretti, Francesco;
Di Bernardo, Diego

Publication type:

Article

FacPad: Bayesian sparse factor modeling for the inference of pathways responsive to drug treatment.

Published in:

Bioinformatics, 2012, v. 28, n. 20, p. 2662, doi. 10.1093/bioinformatics/bts502

By:

Ma, Haisu;
Zhao, Hongyu

Publication type:

Article

A system-level approach for deciphering the transcriptional response to prion infection.

Published in:

Bioinformatics, 2011, v. 27, n. 24, p. 3407, doi. 10.1093/bioinformatics/btr580

By:

Zampieri, Mattia;
Legname, Giuseppe;
Segrè, Daniel;
Altafini, Claudio

Publication type:

Article

Generation of a consensus protein domain dictionary.

Published in:

Bioinformatics, 2011, v. 27, n. 1, p. 46, doi. 10.1093/bioinformatics/btq625

By:

Schaeffer, R. Dustin;
Jonsson, Amanda L.;
Simms, Andrew M.;
Daggett, Valerie

Publication type:

Article

The "in's and outs" of laser hair removal: a mini review.

Published in:

Journal of Cosmetic & Laser Therapy, 2019, v. 21, n. 6, p. 316, doi. 10.1080/14764172.2019.1605449

By:

Thomas, Mandy M.;
Houreld, Nicolette N.

Publication type:

Article

Cryo-EM structures of inhibitory antibodies complexed with arginase 1 provide insight into mechanism of action.

Published in:

Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02444-z

By:

Palte, Rachel L.;
Juan, Veronica;
Gomez-Llorente, Yacob;
Bailly, Marc Andre;
Chakravarthy, Kalyan;
Chen, Xun;
Cipriano, Daniel;
Fayadat-Dilman, Laurence;
Gathiaka, Symon;
Greb, Heiko;
Hall, Brian;
Handa, Mas;
Hsieh, Mark;
Kofman, Esther;
Lin, Heping;
Miller, J. Richard;
Nguyen, Nhung;
O'Neil, Jennifer;
Shaheen, Hussam;
Sterner, Eric

Publication type:

Article

Structure-function analysis of purified proanthocyanidins reveals a role for polymer size in suppressing inflammatory responses.

Published in:

Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02408-3

By:

Andersen-Civil, Audrey Inge Schytz;
Leppä, Milla Marleena;
Thamsborg, Stig M.;
Salminen, Juha-Pekka;
Williams, Andrew R.

Publication type:

Article

Systems biology: MoA on DeMAND.

Published in:

Nature Reviews Genetics, 2015, v. 16, n. 9, p. 498, doi. 10.1038/nrg3996

By:

McCarthy, Nicola

Publication type:

Article

Transcription: Stress unleashes the DoGs.

Published in:

Nature Reviews Genetics, 2015, v. 16, n. 9, p. 497, doi. 10.1038/nrg3994

By:

Waldron, Denise

Publication type:

Article