Works about BINDING sites

Results: 5000

Stable Na+ Ion Storage via Dual Active Sites Utilization in Covalent Organic Framework‐Carbon Nanotube Composite.

Published in:

ChemSusChem, 2025, v. 18, n. 10, p. 1, doi. 10.1002/cssc.202402325

By:

Dey, Anupam;
Pramanik, Atin;
Purohit, Sougat;
Biswas, Sandip;
Chattopadhyay, Shreyasi;
Pieshkov, Tymofii S.;
Sai Gautam, Gopalakrishnan;
Ajayan, Pulickel M.;
Maji, Tapas Kumar

Publication type:

Article

Wnt signalosome assembly is governed by conformational flexibility of Axin and by the AP2 clathrin adaptor.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-59984-9

By:

Gammons, Melissa V.;
Franco-Echevarría, Elsa;
Li, Tie-Mei;
Rutherford, Trevor J.;
Renko, Miha;
Batters, Christopher;
Bienz, Mariann

Publication type:

Article

Interaction Between Allopregnanolone and Amiloride Binding Sites on the GABAA Receptor.

Published in:

Cell Biochemistry & Biophysics, 2025, v. 83, n. 2, p. 2453, doi. 10.1007/s12013-024-01654-6

By:

Bukanova, Julia V.;
Kondratenko, Rodion V.;
Solntseva, Elena I.

Publication type:

Article

Virtual Probing on the Influence of Ca2+ and Zn2+ Bound S100A8 and S100A9 Proteins Towards their Interaction Against Pattern Recognition Receptors Aggravating Rheumatoid Arthritis.

Published in:

Cell Biochemistry & Biophysics, 2025, v. 83, n. 2, p. 1919, doi. 10.1007/s12013-024-01600-6

By:

Paramasivam, Sivasakthi;
Murugesan, Janaranjani;
Vedagiri, Hemamalini;
Perumal, Senthamil Selvan;
Ekambaram, Sanmuga Priya

Publication type:

Article

Harnessing Phytochemicals to Regulate Catalytic Residues of Alpha-Amylase and Alpha-Glucosidase in Type 2 Diabetes.

Published in:

Cell Biochemistry & Biophysics, 2025, v. 83, n. 2, p. 1657, doi. 10.1007/s12013-024-01575-4

By:

Dhanasekaran, Sivaraman;
Jeyabalan, Srikanth;
Choudhury, Abbas Alam;
Rajeswari, Vijayarangan Devi;
Ramanathan, Gnanasambandan;
Thamaraikani, Tamilanban;
Sekar, Mahendran;
Subramaniyan, Vetriselvan;
Shing, Wong Ling

Publication type:

Article

The knowledge driven DBTL cycle provides mechanistic insights while optimising dopamine production in Escherichia coli.

Published in:

Microbial Cell Factories, 2025, v. 24, n. 1, p. 1, doi. 10.1186/s12934-025-02729-6

By:

Hägele, Lorena;
Trachtmann, Natalia;
Takors, Ralf

Publication type:

Article

Enhancing Shiga toxin detection using surface plasmon resonance a study of antibody immobilization strategies.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-01686-9

By:

Karbalaee, Zahra;
Rezayan, Ali Hossein;
Taheri, Ramezan Ali;
Mirhosseini, Seyed Ali;
Barshan-Tashnizi, Mohammad

Publication type:

Article

Design and Evaluation of Bivalent K‐Ras Inhibitors That Target the CAAX Binding Site and the Acidic Surface of Farnesyltransferase and Geranylgeranyltransferase I.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 27, p. 1, doi. 10.1002/chem.202500306

By:

Horiuchi, Naomi;
Omer, Rania;
Sugino, Fumitoshi;
Ogino, Nanami;
Inoue, Yoshihisa;
Aslamuzzaman, Kazi;
Suzuki, Takeyuki;
Sebti, Said M.;
Ohkanda, Junko

Publication type:

Article

Impact of nonsynonymous single nucleotide polymorphisms in PROCR gene on protein stability and thrombotic risk: a molecular dynamic approach.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1580993

By:

Abuagla, Hytham Ahmed;
Adam, Khalid Mohamed;
Elangeeb, Mohamed E.;
Ahmed, Elsadig Mohamed;
Ali, Elshazali W.;
Edris, Ali M.;
MohamedAhmed, Abubakr Ali Elamin;
Eltieb, Elmoiz Idris;
Khalid, Tarig Babikir Algak;
Elamin, Bahaeldin K.;
Osman, Hiba Mahgoub Ali;
Idris, Ebtehal Salih

Publication type:

Article

Insight into improved specificity and thermostability of Geobacillus zalihae T1 lipase by introducing novel molecular interactions via phenylalanin to cysteine substitution.

Published in:

3 Biotech, 2025, v. 15, n. 6, p. 1, doi. 10.1007/s13205-025-04330-5

By:

Albayati, Samah Hashim;
Shabeeb, Muna Hilal;
Akinola, Oluwasola Michael;
Nezhad, Nima Ghahremani;
Chor, Adam Leow Thean;
bin Mohamad Ali, Mohd Shukuri;
binti Mohd Shariff, Fairolniza;
binti Muhd Noor, Noor Dina;
Abd Rahman, Raja Noor Zaliha Raja

Publication type:

Article

Assessment of the Effects of Single-Domain Anti-Idiotypic Distribution Enhancers on the Disposition of Trastuzumab and on the Efficacy of a PE24-Trastuzumab Immunotoxin.

Published in:

Cancers, 2025, v. 17, n. 9, p. 1468, doi. 10.3390/cancers17091468

By:

Chen, Ping;
Zhang, Yu;
Bordeau, Brandon M.;
Balthasar, Joseph P.

Publication type:

Article

Mapping the Binding Sites of CA125-Specific Antibodies on a Revised Molecular Model of MUC16.

Published in:

Cancers, 2025, v. 17, n. 9, p. 1458, doi. 10.3390/cancers17091458

By:

Wang, Chien-Wei;
Srivastava, Anubhuti;
Hanson, Eliza K.;
McEntee, Caitlin R.;
Nair, Trisha;
March, Jane C.;
Whelan, Rebecca J.

Publication type:

Article

Overexpression of StTCP10 Alters Tuber Number and Size in Potato (Solanum tuberosum L.).

Published in:

Plants (2223-7747), 2025, v. 14, n. 9, p. 1403, doi. 10.3390/plants14091403

By:

Wang, Tingting;
Chen, Xinyue;
Li, Shuangshuang;
Wang, Ping;
Wang, Yongbin;
Huang, Binquan

Publication type:

Article

iProtDNA-SMOTE: Enhancing protein-DNA binding sites prediction through imbalanced graph neural networks.

Published in:

PLoS ONE, 2025, v. 20, n. 5, p. 1, doi. 10.1371/journal.pone.0320817

By:

Huang, Ruiyan;
Qiu, Wangren;
Xiao, Xuan;
Lin, Weizhong

Publication type:

Article

MiR-455-5p Mitigates Interleukin-1 β-induced Chondrocyte Damage Linked to Osteoarthritis by Targeting TNFAIP8.

Published in:

Journal of Physiological Investigation (JPI), 2025, v. 68, n. 2, p. 100, doi. 10.4103/ejpi.EJPI-D-24-00102

By:

Zhang, Tao;
Wang, Wei;
Sun, Jinlei;
Luo, Long;
Li, Yuan;
Xu, Zhixiong;
Xu, Wensheng

Publication type:

Article

Predictive biophysical neural network modeling of a compendium of in vivo transcription factor DNA binding profiles for Escherichia coli.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-58862-8

By:

Lally, Patrick;
Gómez-Romero, Laura;
Tierrafría, Víctor H.;
Aquino, Patricia;
Rioualen, Claire;
Zhang, Xiaoman;
Kim, Sunyoung;
Baniulyte, Gabriele;
Plitnick, Jonathan;
Smith, Carol;
Babu, Mohan;
Collado-Vides, Julio;
Wade, Joseph T.;
Galagan, James E.

Publication type:

Article

Blocking Plasmodium Merozoite Invasion of Red Blood Cells: Molecular Docking Analysis of Small Molecule Inhibitors of the RH5-CyRPA-RIPR Complex.

Published in:

Journal of Computational Biophysics & Chemistry, 2025, v. 24, n. 8, p. 1039, doi. 10.1142/S2737416525500097

By:

Lamptey, Eugene;
Ofosu, Belinda;
Hanson, George;
Sakyi, Patrick O.;
Partey, Frederica;
Miller III, Whelton A.;
Kwofie, Samuel K.;
Mensah-Brown, Henrietta E.

Publication type:

Article

Front Cover: Discovery of 1,3,4‐Oxadiazin‐5‐One Derivative CJ1‐34 as a Partial ATP Synthase Inhibitor for CNS Applications.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 24, p. 1, doi. 10.1002/chem.202582401

By:

Jie, Caitlin V. M. L.;
Delparente, Aro;
Reichert, Lisa;
Albrecht, Manuela;
Atz, Kenneth;
Schneider, Gisbert;
Schibli, Roger;
Mu, Linjing

Publication type:

Article

Proteome-wide determinants of co-translational chaperone binding in bacteria.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-59067-9

By:

Galmozzi, Carla Verónica;
Tippmann, Frank;
Wruck, Florian;
Auburger, Josef Johannes;
Kats, Ilia;
Guennigmann, Manuel;
Till, Katharina;
O´Brien, Edward P.;
Tans, Sander J.;
Kramer, Günter;
Bukau, Bernd

Publication type:

Article

Linkers in Action: Exploring Fusion Enzymes for Oxyfunctionlizations in Non‐Conventional Media Through Experiments and Simulations.

Published in:

ChemCatChem, 2025, v. 17, n. 9, p. 1, doi. 10.1002/cctc.202401893

By:

Ma, Yu;
Bittner, Jan Philipp;
Vernet, Guillem;
Zhang, Ningning;
Kara, Selin

Publication type:

Article

A KAN-based hybrid deep neural networks for accurate identification of transcription factor binding sites.

Published in:

PLoS ONE, 2025, v. 20, n. 5, p. 1, doi. 10.1371/journal.pone.0322978

By:

He, Guodong;
Ye, Jiahao;
Hao, Huijun;
Chen, Wei

Publication type:

Article

Effect of silencing Ras homolog family member C on proliferation, invasion, and migration of salivary adenoid cystic carcinoma.

Published in:

West China Journal of Stomatology, 2024, v. 42, n. 6, p. 723, doi. 10.7518/hxkq.2024.2024092

By:

Yu Wenyuan;
Zhao Peng;
Shao Yu;
Xu Yong;
Xu Jin;
Xie Lei;
Yu Chenghao;
He Qiuping;
Chen Zhenggang

Publication type:

Article

Genome‐Wide Association Study Identifies a Locus at 17p13 to Be Associated With Intestinal Malrotation.

Published in:

World Journal of Surgery, 2025, v. 49, n. 5, p. 1282, doi. 10.1002/wjs.12575

By:

Gaitanidis, Apostolos;
Christensen, Mathias A.;
Dorken Gallastegi, Ander;
Breen, Kerry A.;
Velmahos, George C.;
Kaafarani, Haytham M. A.;
Farhat, Maha R.

Publication type:

Article

In silico design of novel pyridazine derivatives as balanced multifunctional agents against Alzheimer's disease.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-98182-x

By:

Aloui, Mourad;
El fadili, Mohamed;
Mujwar, Somdutt;
Er-rajy, Mohammed;
Abuelizz, Hatem A.;
Er-rahmani, Sara;
Zarougui, Sara;
Menana, Elhalaoui

Publication type:

Article

Molecular Docking, Pharmacophore Modeling, 3D QSAR, Molecular Dynamics Simulation and MMPBSA Studies on Hydrazine-Linked Thiazole Analogues as MAO-B Inhibitors.

Published in:

Journal of Computational Biophysics & Chemistry, 2025, v. 24, n. 6, p. 709, doi. 10.1142/S2737416524500790

By:

Fathima, C. Zakiya;
James, Jainey P.;
Dwivedi, Prarambh S. R.;
Sindhu, T. J.

Publication type:

Article

Molecular Docking Studies of Synthesized Pyridazinone Scaffolds as Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs).

Published in:

Polycyclic Aromatic Compounds, 2025, v. 45, n. 3, p. 376, doi. 10.1080/10406638.2024.2407565

By:

Yusuf, Mohd;
Abdulaziz, Osama;
Aljuaid, Abdulelah;
Allahyani, Mamdouh;
Almehmadi, Mazen;
Alzahrani, Abdullah Yahya Abdullah;
Verma, Shivani;
Asif, Mohammad

Publication type:

Article

Progress in the study of curcumin metabolism in vivo.

Published in:

Journal of Asian Natural Products Research, 2025, v. 27, n. 5, p. 639, doi. 10.1080/10286020.2024.2420619

By:

Zhong, Shi-Jie;
Xing, Ya-Dong;
Dong, Lu-Yao;
Chen, Yi;
Liu, Nan;
Wang, Zeng-Ming;
Zhang, Hui;
Zheng, Ai-Ping

Publication type:

Article

Coordination of cell envelope biology by Escherichia coli MarA protein potentiates intrinsic antibiotic resistance.

Published in:

PLoS Genetics, 2025, v. 21, n. 5, p. 1, doi. 10.1371/journal.pgen.1011639

By:

Trigg, Alexandra E.;
Sharma, Prateek;
Grainger, David C.

Publication type:

Article

Mechanistic insights into Alpha-Synuclein binding to P2RX7: A molecular dynamic and docking study.

Published in:

PLoS ONE, 2025, v. 20, n. 5, p. 1, doi. 10.1371/journal.pone.0319098

By:

Kumar, Mukesh;
Singh, Kanchan;
Joshi, Jayant;
Sharma, Shreya;
Kumar, Amit;
Irungbam, Karuna;
Mahawar, Manish;
Saini, Mohini

Publication type:

Article

Correction: Investigating genotype-phenotype correlation of limb-girdle muscular dystrophy R8: association of clinical severity, protein biological function and protein oligomerization.

Published in:

2025

By:

Liang, Xiongda;
Si, Jiameng;
Xie, Hongting;
Guan, Yuqing;
Lin, Wanying;
Lin, Zezhang;
Zheng, Ganwei;
Wei, Xiaofeng;
Xiong, Xingbang;
Zhuang, Zhengfei;
Shang, Xuan

Publication type:

Correction Notice

DockEM: an enhanced method for atomic-scale protein–ligand docking refinement leveraging low-to-medium resolution cryo-EM density maps.

Published in:

Briefings in Bioinformatics, 2025, v. 26, n. 2, p. 1, doi. 10.1093/bib/bbaf091

By:

Zou, Jing;
Zhang, Wenyi;
Hu, Jun;
Zhou, Xiaogen;
Zhang, Biao

Publication type:

Article

Virtual screening and molecular dynamics simulation study of approved drugs as a binder to the linoleic acid binding site on spike protein of SARS-CoV-2 and double mutant (E484Q and L452R).

Published in:

Indian Journal of Pharmacology, 2022, v. 54, n. 6, p. 431, doi. 10.4103/ijp.ijp_111_22

By:

Prajapat, Manisha;
Sarma, Phulen;
Shekhar, Nishant;
Chauhan, Arushi;
Kaur, Gurjeet;
Bhattacharyya, Anusuya;
Avti, Pramod;
Choudhary, Gajendra;
Bansal, Seema;
Sharma, Saurabh;
Kaur, Hardeep;
Kumar, Subodh;
Mann, Harvinder;
Raja, Anupam;
Singh, Ashutosh;
Singh, Rahul;
Sharma, Amit;
Prakash, Ajay;
Medhi, Bikash

Publication type:

Article

Cytokeratin 5/14-positive breast cancer: true basal phenotype confined to BRCA1 tumors.

Published in:

Modern Pathology, 2005, v. 18, n. 10, p. 1321, doi. 10.1038/modpathol.3800456

By:

Laakso, Mervi;
Loman, Niklas;
Borg, Åke;
Isola, Jorma

Publication type:

Article

Natural Selection Molds Genomic Insulator Elements

Published in:

PLoS Biology, 2012, v. 10, n. 11, p. 1, doi. 10.1371/journal.pbio.1001421

By:

Robinson, Richard

Publication type:

Article

Adaptive Evolution and the Birth of CTCF Binding Sites in the Drosophila Genome

Published in:

PLoS Biology, 2012, v. 10, n. 11, p. 1, doi. 10.1371/journal.pbio.1001420

By:

Ni, Xiaochun;
Zhang, Yong E.;
Nègre, Nicolas;
Chen, Sidi;
Long, Manyuan;
White, Kevin P.

Publication type:

Article

Capzb2 Interacts with β-Tubulin to Regulate Growth Cone Morphology and Neurite Outgrowth.

Published in:

PLoS Biology, 2009, v. 7, n. 10, p. 1, doi. 10.1371/journal.pbio.1000208

By:

Davis, David A.;
Wilson, Meredith H.;
Giraud, Jodel;
Zhigang Xie;
Huang-Chun Tseng;
England, Cheryl;
Herscovitz, Haya;
Li-Huei Tsai;
Delalle, Ivana

Publication type:

Article

Transcriptional Dysregulation in NIPBL and Cohesin Mutant Human Cells.

Published in:

PLoS Biology, 2009, v. 7, n. 5, p. 1, doi. 10.1371/journal.pbio.1000119

By:

Jinglan Liu;
Zhe Zhang;
Bando, Masashige;
Itoh, Takehiko;
Deardorff, Matthew A.;
Clark, Dinah;
Kaur, Maninder;
Tandy, Stephany;
Kondoh, Tatsuro;
Rappaport, Eric;
Spinner, Nancy B.;
Vega, Hugo;
Jackson, Laird G.;
Shirahige, Katsuhiko;
Krantz, Ian D.

Publication type:

Article

The Active Site of a Carbohydrate Esterase Displays Divergent Catalytic and Noncatalytic Binding Functions.

Published in:

PLoS Biology, 2009, v. 7, n. 3, p. e1000071, doi. 10.1371/journal.pbio.1000071

By:

Montanier, Cedric;
Money, Victoria A.;
Pires, Virginia M. R.;
Flint, James E.;
Pinheiro, Benedita A.;
Goyal, Arun;
Prates, José A. M.;
Izumi, Atsushi;
Stålbrand, Henrik;
Morland, Carl;
Cartmell, Alan;
Kolenova, Katarina;
Topakas, Evangelos;
Dodson, Eleanor J.;
Bolam, David N.;
Davies, Gideon J.;
Fontes, Carlos M. G. A.;
Gilbert, Harry J.

Publication type:

Article

The Influence of Catalysis on Mad2 Activation Dynamics.

Published in:

PLoS Biology, 2009, v. 7, n. 1, p. e1000010, doi. 10.1371/journal.pbio.1000010

By:

Simonetta, Marco;
Manzoni, Romilde;
Mosca, Roberto;
Mapelli, Marina;
Massimiliano, Lucia;
Vink, Martin;
Novak, Bela;
Musacchio, Andrea;
Ciliberto, Andrea

Publication type:

Article

Bcl-XL Inhibits Membrane Permeabilization by Competing with Bax.

Published in:

PLoS Biology, 2008, v. 6, n. 6, p. e147, doi. 10.1371/journal.pbio.0060147

By:

Billen, Lieven P.;
Kokoski, Candis L.;
Lovell, Jonathan F.;
Leber, Brian;
Andrews, David W.

Publication type:

Article

The Ticket to Transport.

Published in:

PLoS Biology, 2008, v. 6, n. 6, p. e144, doi. 10.1371/journal.pbio.0060144

By:

Hoff, Mary

Publication type:

Article

Making the Connection: Polar Sites Are Key to Assembly in Many Immune Receptors.

Published in:

PLoS Biology, 2006, v. 4, n. 5, p. e168, doi. 10.1371/journal.pbio.0040168

By:

Hoff, Mary

Publication type:

Article

The Unfolding of Amyloid's True Colors.

Published in:: PLoS Biology, 2006, v. 4, n. 1, p. e8, doi. 10.1371/journal.pbio.0040008
Publication type:: Article

Finding Sigma-Controlled Promoters.

Published in:: PLoS Biology, 2006, v. 4, n. 1, p. e13, doi. 10.1371/journal.pbio.0040013
Publication type:: Article

Functional Identification of Catalytic Metal Ion Binding Sites within RNA.

Published in:

PLoS Biology, 2005, v. 3, n. 8, p. 1, doi. 10.1371/journal.pbio.0030277

By:

Hougland, James L;
Kravchuk, Alexander V;
Herschlag, Daniel;
Piccirilli, Joseph A

Publication type:

Article

Kupffer cell stimulation in the isolated perfused rat liver triggers nuclear factor-κB DNA binding activity.

Published in:

Redox Report, 2003, v. 8, n. 6, p. 341, doi. 10.1179/135100003225003375

By:

Romanque, Pamela;
Tapia, Gladys;
Videla, Luis A.

Publication type:

Article

Construction of transcript regulation mechanism prediction models based on binding motif environment of transcription factor AoXlnR in Aspergillus oryzae.

Published in:

Journal of Bioinformatics & Computational Biology, 2024, v. 22, n. 3, p. 1, doi. 10.1142/S0219720024500173

By:

Oka, Hiroya;
Kojima, Takaaki;
Kato, Ryuji;
Ihara, Kunio;
Nakano, Hideo

Publication type:

Article

Behavioral dynamics of bacteriophage gene regulatory networks.

Published in:

Journal of Bioinformatics & Computational Biology, 2022, v. 20, n. 5, p. 1, doi. 10.1142/S0219720022500214

By:

Melkus, Gatis;
Cerans, Karlis;
Freivalds, Karlis;
Lace, Lelde;
Zajakina, Darta;
Viksna, Juris

Publication type:

Article

Prediction of nucleosome dynamic interval based on long–short-term memory network (LSTM).

Published in:

Journal of Bioinformatics & Computational Biology, 2022, v. 20, n. 3, p. 1, doi. 10.1142/S0219720022500093

By:

Liu, Jianli;
Zhou, Deliang;
Jin, Wen

Publication type:

Article

Quantitative structure–activity relationship modeling reveals the minimal sequence requirement and amino acid preference of sirtuin-1's deacetylation substrates in diabetes mellitus.

Published in:

Journal of Bioinformatics & Computational Biology, 2022, v. 20, n. 3, p. 1, doi. 10.1142/S0219720022500081

By:

Shao, X.;
Kong, W.;
Li, Y.;
Zhang, S.

Publication type:

Article